Academic literature on the topic 'Interbody spinal fusion device'

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Journal articles on the topic "Interbody spinal fusion device"

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Burkus, J. Kenneth, Kevin Foley, Regis Haid, and Jean-Charles LeHuec. "Surgical Interbody Research Group–radiographic assessment of interbody fusion devices: fusion criteria for anterior lumbar interbody surgery." Neurosurgical Focus 10, no. 4 (April 2001): 1–9. http://dx.doi.org/10.3171/foc.2001.10.4.12.

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The authors present their radiographic criteria for assessing fusion of the lumbar spine after anterior interbody fusion with intradiscal implants. These criteria include the assessment of plain radiographs, dynamic motion radiographs, and thin-cut computerized tomography scans. Fusion within the instrumented spinal motion segment can be determined using radiographic evaluation to assess spinal alignment on sequential examinations, angular and translational changes on dynamic motion studies, and device–host interface, and to identify new bone formation and bone remodeling. Finally, to aid the clinician in assessing fusion, the authors describe the five zones of fusion within the intervertebral disc space.
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Toth, Jeffrey M., Bradley T. Estes, Mei Wang, Howard B. Seim, Jeffrey L. Scifert, A. Simon Turner, and G. Bryan Cornwall. "Evaluation of 70/30 poly (l-lactide-co-d,l-lactide) for use as a resorbable interbody fusion cage." Journal of Neurosurgery: Spine 97, no. 4 (November 2002): 423–32. http://dx.doi.org/10.3171/spi.2002.97.4.0423.

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Object. Titanium lumbar interbody spinal fusion devices are reported to be 90% effective in cases requiring single-level lumbar interbody arthrodesis, although radiographic determination of fusion has been debated. Methods. Using blinded radiographic, biomechanical, histological, and statistical measures, researchers in the present study evaluated a radiolucent 70/30 poly(l-lactide-co-d,l-lactide) interbody fusion device packed with autograft or recombinant human bone morphogenetic protein—2 on a collagen sponge in 25 sheep at 3, 6, 12, 18, and 24 months. A trend of increased fusion stiffness, radiographic fusion, and histologically confirmed fusion was demonstrated at 3 months to 24 months postimplantation. Device degradation was associated with a mild to moderate chronic inflammatory response at all postoperative sacrifice times. Conclusions. Use of this material in interbody fusion may be a viable alternative to metals.
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Feng, Shitong, Zihan Fan, Jiashuai Ni, Yong Yang, and Qi Fei. "New combination of IntraSPINE device and posterior lumbar interbody fusion for rare skipped-level lumbar disc herniation: a case report and literature review." Journal of International Medical Research 48, no. 8 (August 2020): 030006052094976. http://dx.doi.org/10.1177/0300060520949764.

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Posterior lumbar interbody fusion is an open surgical technique that has been widely used for the treatment of degenerative lumbar disease. However, traditional lumbar spinal fusion, especially long-segment fusion surgery, is associated with several complications. The IntraSPINE (Cousin Biotech, Wervicq-Sud, France) is a new device for non-fusion lumbar spine surgery that is used as an alternative for the treatment of degenerative lumbar disease. Although the designer of the IntraSPINE proposed indications for its use, including combination of the device with lumbar spinal fusion for the treatment of degenerative lumbar disease, use of the IntraSPINE has not been reported in the clinical literature. In the present case, we boldly combined the IntraSPINE device and posterior lumbar interbody fusion for the treatment of skipped-level lumbar disc herniation to explore the indications of the IntraSPINE and report its clinical outcomes.
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Kumar Mishra, Sandeep, Kushal Haresh Gori, and Deepak C. E. "Comparison of outcome in lumbar spine instability treated surgically with pedicle screw fixation with or without interbody fusion device (cage)." International Journal of Research in Medical Sciences 6, no. 3 (February 22, 2018): 937. http://dx.doi.org/10.18203/2320-6012.ijrms20180619.

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Background: Lumbar spinal fusion was introduced approximately 70 years ago and has evolved as a treatment option for symptomatic spinal instability, spinal stenosis, spondylolisthesis, and degenerative scoliosis. Broader applications including use as a treatment of chronic low back pain and recurrent radiculopathy have resulted in a dramatic increase in the rates of lumbar fusion procedures within the last decade.Methods: A retrospective and prospective study to be carried out for 40 patients who were assigned in the following groups: Group 1 (n=20) consisted of patients who underwent lumbar interbody fusion with pedicle screw and bone graft, and Group 2 (n=20) consisted of patients treated by lumbar interbody fusion with pedicle screw and interbody cage.Results: Most of patients with lumbar spine instability were in 4th and 5th decade of life with average age of 46.75 yrs and female predominance with 26 (65%) cases.65% of Instability was found due to Spondylolisthesis. PLIF with Cage showed better scores than BG in terms of ODI, VAS, SF-36, Benzel’s modified Japanese scores at end of 1 year, which is statistically not significant.Conclusions: Lumbar spine instability is more common in 4th and 5th decade of life with female predominance, commonest level of instability being L4-L5 and commonest mode was Spondylolisthesis. PLIF with Cage is associated with greater operative time and lesser blood loss. Patients with PLIF + Cage had better neurological improvement, pain reduction, reduced disability, generalised well-being and satisfaction as evident by Modified Benzel’s Japanese scales, VAS, ODI, and SF-36 scores respectively, which is statistically not significant. Addition of an interbody fusion device (Cage) helps in greater stability, lower implant failure, higher fusion rate and better functional outcome in patient treated with PLIF for lumbar spine instability.
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Spicher, Anna, Werner Schmoelz, Rene Schmid, Hannes Stofferin, and Niall J. A. Craig. "Functional and radiographic evaluation of an interspinous device as an adjunct for lumbar interbody fusion procedures." Biomedical Engineering / Biomedizinische Technik 65, no. 2 (April 28, 2020): 183–89. http://dx.doi.org/10.1515/bmt-2018-0086.

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AbstractIn the last decades, several interspinous process devices were designed as a minimally invasive treatment option for spinal stenosis. In order to minimise surgical trauma, interspinous process devices were recently discussed as an alternative posterior fixation in vertebral interbody fusions. Therefore, the purpose of this study was to evaluate the effect of a newly designed interspinous device with polyester bands (PBs) on range of motion (RoM) and centre of rotation (CoR) of a treated motion segment in comparison with an established interspinous device with spikes (SC) as well as with pedicle screw instrumentation in lumbar fusion procedures. Flexibility tests with an applied pure moment load of 7.5 Nm were performed in six monosegmental thoracolumbar functional spinal units (FSUs) in the following states: (a) native, (b) native with PB device, (c) intervertebral cage with PB device, (d) cage with SC and (e) cage with internal fixator. The resulting RoM was normalised to the native RoM. The CoR was determined of X-ray images taken in maximal flexion and extension during testing. In flexion and extension, the PB device without and with the cage reduced the RoM of the native state to 58% [standard deviation (SD) 17.8] and 53% (SD 15.7), respectively. The SC device further reduced the RoM to 27% (SD 16.8), while the pedicle screw instrumentation had the most reducing effect to 17% (SD 17.2) (p < 0.01). In lateral bending and axial rotation, the interspinous devices had the least effect on the RoM. Compared to the native state, for all instrumentations the CoR showed a small shift towards cranial. In the anterior-posterior direction, the SC device and the pedicle screw instrumentation shifted the CoR towards the posterior wall. The interspinous devices significantly reduced the RoM in flexion/extension, while in axial rotation and lateral bending only the internal fixator had a significant effect on the RoM.
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Crawford, Brooke, Christopher Lenarz, J. Tracy Watson, and Dirk Alander. "Complication with Removal of a Lumbar Spinal Locking Plate." Case Reports in Orthopedics 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/787249.

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Introduction. The use of locking plate technology for anterior lumbar spinal fusion has increased stability of the vertebral fusion mass over traditional nonconstrained screw and plate systems. This case report outlines a complication due to the use of this construct.Case. A patient with a history of L2 corpectomy and anterior spinal fusion presented with discitis at the L4/5 level and underwent an anterior lumbar interbody fusion (ALIF) supplemented with a locking plate placed anterolaterally for stability. Fifteen months after the ALIF procedure, he returned with a hardware infection. He underwent debridement of the infection site and removal of hardware.Results. Once hardware was exposed, removal of the locking plate screws was only successful in one out of four screws using a reverse thread screw removal device. Three of the reverse thread screw removal devices broke in attempt to remove the subsequent screws. A metal cutting drill was then used to break hoop stresses associated with the locking device and the plate was removed.Conclusion. Anterior locking plates add significant stability to an anterior spinal fusion mass. However, removal of this hardware can be complicated by the inherent properties of the design with significant risk of major vascular injury.
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Kumar, Manoj, Prashanth Dhanraj, and Deepak Shivanna. "Results of Anterior Spinal Fusion in Spondylolisthesis with or without Interbody Fusion Device (CAGE)." Global Spine Journal 5, no. 1_suppl (May 2015): s—0035–1554311—s—0035–1554311. http://dx.doi.org/10.1055/s-0035-1554311.

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Cadel, Eileen, Ember Krech, Paul Arnold, and Elizabeth Friis. "Stacked PZT Discs Generate Necessary Power for Bone Healing through Electrical Stimulation in a Composite Spinal Fusion Implant." Bioengineering 5, no. 4 (October 23, 2018): 90. http://dx.doi.org/10.3390/bioengineering5040090.

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Electrical stimulation devices can be used as adjunct therapy to lumbar spinal fusion to promote bone healing, but their adoption has been hindered by the large battery packs necessary to provide power. Piezoelectric composite materials within a spinal interbody cage to produce power in response to physiological lumbar loads have recently been investigated. A piezoelectric macro-fiber composite spinal interbody generated sufficient power to stimulate bone growth in a pilot ovine study, despite fabrication challenges. The objective of the present study was to electromechanically evaluate three new piezoelectric disc composites, 15-disc insert, seven-disc insert, and seven-disc Compliant Layer Adaptive Composite Stack (CLACS) insert, within a spinal interbody, and validate their use for electrical stimulation and promoting bone growth. All implants were electromechanically assessed under cyclic loads of 1000 N at 2 Hz, representing physiological lumbar loading. All three configurations produced at least as much power as the piezoelectric macro-fiber composites, validating the use of piezoelectric discs for this application. Future work is needed to characterize the electromechanical performance of commercially manufactured piezoelectric stacks under physiological lumbar loads, and mechanically assess the composite implants according to FDA guidelines for lumbar interbody fusion devices.
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Alexander, Joseph T., Charles L. Branch, Brian R. Subach, and Regis W. Haid. "Applications of a resorbable interbody spacer in posterior lumbar interbody fusion." Journal of Neurosurgery: Spine 97, no. 4 (November 2002): 468–72. http://dx.doi.org/10.3171/spi.2002.97.4.0468.

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✓ Polyhydroxy acids are a promising class of resorbable materials with potential applications in spinal surgery. One such polymer, MacroPore (MacroPore Biosurgery, Inc.), offers a balance of strength, predictable degradation, lack of stimulus of foreign body reaction, and biocompatibility with neural tissue. MacroPore can be formed into an array of shapes and can be manufactured, sterilized, and stored using conventional techniques. Limited clinical experience has been gained with resorbable implants used as load-sharing devices in a posterior lumbar interbody fusion construct.
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Takemoto, Mitsuru, Shunsuke Fujibayashi, Masashi Neo, Kazutaka So, Norihiro Akiyama, Tomiharu Matsushita, Tadashi Kokubo, and Takashi Nakamura. "A porous bioactive titanium implant for spinal interbody fusion: an experimental study using a canine model." Journal of Neurosurgery: Spine 7, no. 4 (October 2007): 435–43. http://dx.doi.org/10.3171/spi-07/10/435.

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Object Porous biomaterials with adequate pore structure and appropriate mechanical properties are expected to provide a new generation of devices for spinal interbody fusion because of their potential to eliminate bone grafting. The purpose of this study was to evaluate the fusion characteristics of porous bioactive titanium implants using a canine anterior interbody fusion model. Methods Porous titanium implants sintered with volatile spacer particles (porosity 50%, average pore size 303 μm, compressive strength 116.3 MPa) were subjected to chemical and thermal treatments that give a bioactive microporous titania layer on the titanium surface (BT implant). Ten adult female beagle dogs underwent anterior lumbar interbody fusion at L6–7 using either BT implants or nontreated (NT) implants, followed by posterior spinous process wiring and facet screw fixation. Radiographic evaluations were performed at 1, 2, and 3 months postoperatively using X-ray fluoroscopy. Animals were killed 3 months postoperatively, and fusion status was evaluated by manual palpation and histological examination. Results Interbody fusion was confirmed in all five dogs in the BT group and three of five dogs in the NT group. Histological examination demonstrated a large amount of new bone formation with marrowlike tissue in the BT implants and primarily fibrous tissue formation in the NT implants. Conclusions Bioactive treatment effectively enhanced the fusion ability of the porous titanium implants. These findings, coupled with the appropriate mechanical properties in load-bearing conditions, indicate that these porous bioactive titanium implants represent a new generation of biomaterial for spinal interbody fusion.
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Dissertations / Theses on the topic "Interbody spinal fusion device"

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Sudershan, Sushil Prasen. "Biomechanical Evaluation of Lumbar Interbody Fusion Surgeries with Varying Interbody Device Shapes, Material Properties, and Supplemental Fixation." University of Toledo / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1513267199037192.

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Sasidhar, Vadapalli. "Stability imparted by a posterior lumbar interbody fusion cage following surgery : a biomechanical evaluation /." See Full Text at OhioLINK ETD Center (Requires Adobe Acrobat Reader for viewing), 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1092370385.

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Thesis (M.S.B.)--University of Toledo, 2004.
Typescript. "A thesis [submitted] as partial fulfillment of the requirements of the Master of Science degree in Bioengineering." Bibliography: leaves 4-11.
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Cain, Christopher Marden John. "Assessment of spinal cord blood flow and function in sheep following antero-lateral cervical interbody fusion in animals with and without spinal cord injuries /." Title page, table of contents and summary only, 1991. http://web4.library.adelaide.edu.au/theses/09MD/09mdc135.pdf.

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Heil, Gerlinde Susanne [Verfasser]. "The dose-dependent effect of bone morphogenetic protein 2 on spinal fusion status and adverse effects in right-lateral lumbar interbody fusion in the sheep model : a comparative CT-morphological evaluation / Gerlinde Susanne Heil." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2016. http://d-nb.info/1112133011/34.

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Rossouw, M. M. "An experimental and numerical evaluation of an interbody spinal fusion device." Thesis, 2013. http://hdl.handle.net/10210/8696.

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M.Ing. (Mechanical Engineering)
A stand-alone anterior lumbar interbody fusion device is used to stabilise the spine and restore the disc space height without any other instrumentation. The stand-alone anterior lumbar interbody device is fixed to the adjacent vertebrae using titanium screws. In this research an experimental and numerical investigation on the structural strength of the SASCATM stand-alone anterior lumbar interbody fusion device are presented. The outcome of the investigation will be used as part of the device validation documentation necessary for market approval. The SASCATM device is manufactured from PEEK (a high strength polymer). Tensile and compressive testing was conducted to determine the appropriate mechanical properties of PEEK. The structural integrity of the SASCA device was evaluated by conducting full scale compression testing on a limited number of different design revisions. Comparisons as regards to their loaddisplacement behaviour were made. All specimens were visually inspected. The Finite Element Analysis (FEA) method was used in the numerical investigation of the SASCATM stand-alone anterior lumbar interbody device. Three studies were conducted. The first study aimed at comparing the full scale experimental compressive testing results with the FEA simulation. Although the desired results weren’t achieved, the model gave a fair representation of the initial region of the experimental setup in the sense that it had a similar slope. It was concluded that the nominal stress (4.1 MPa) fell within the proportional limit (35 MPa) as measured during the materials testing. The second study was aimed at determining the displacement at a worst-case load determined from the literature (2.7 kN). The study showed that the maximum Von Mises stress does not exceed the yield strength of the material. The third and final (parametric) study aimed at geometric optimisation of the cages. The motivation for the changes was based on the literature and customer suggestions for improvement. The geometric optimisation intended to show whether a desired increase in graft hole size would have an effect on the structural integrity of the device. The suggestion to move the screw holes of the threehole version closer to the center of the cage was also assessed. It was shown that enlarging the two graft holes does have an effect on the compressive strength. Higher stresses were presented in all but one case. Combining the holes also had an effect on the compressive strength. Movement of the screw holes more medially did have an impact on the compressive strength of the cages. The effect was significant. The closer the holes were to the center of the cage, the higher the Von Mises stress was. This change should therefore be considered before implementation. The results showed that different shapes and sizes of the graft holes do have an impact on the stress of this particular cage. None of the models exceeded the compressive yield strength of the material. The proposed graft hole opening design changes are therefore not warranted for the current SASCATM stand-alone anterior lumbar interbody device.
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Timmer, Mark Davis. "Development of a biodegradable interbody fusion device." Thesis, 2004. http://hdl.handle.net/1911/18717.

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Novel polymer networks based on poly(propylene fumarate) (PPF) and the crosslinking agent poly(propylene fumarate)-diacrylate (PPF-DA) were investigated as a material for a biodegradable interbody fusion cage. The aim of this work was to establish the effect of the macromolecular network structure on the physical properties in order to tailor the material to demonstrate high strength, controllable degradation, and suitable biocompatibility for this implant. The PPF/PPF-DA network structure was characterized with a newly developed technique in which the networks were degraded into simpler linear constituents that provided insight to the macromolecular structure. The double bond conversion and crosslinking density of the polymer networks was controlled by the concentrations of PPF and PPF-DA in the network, as dictated by the double bond ratio of fumarate groups in the PPF backbone to acrylate groups in the PPF-DA crosslinker. Lower double bond ratios yielded higher conversions and a more densely crosslinked network. The network structure was further influenced by the free radical initiator system. The mechanical properties of the PPF/PPF-DA networks increased with decreasing double bond ratios as a result of higher crosslinking densities. Photo-crosslinking produced a stronger material and also facilitated processing of PPF/PPF-DA networks because there is greater control over the crosslinking reaction. Examination of the in vitro degradation behavior of PPF/PPF-DA networks in simulated body fluids showed that the degradation rate was faster for networks with lower crosslinking densities. The biocompatibility of the material was also controlled by the macromolecular structure as PPF/PPF-DA networks with higher double bond conversions and crosslinking densities exhibited no adverse cytotoxicity and enabled fibroblast attachment. A prototype PPF/PPF-DA interbody fusion cage was fabricated by photo-crosslinking the polymers in transparent silicone molds. The PPF/PPF-DA implant demonstrated similar mechanical properties as a clinical approved allograft spacer and suggested that the device can provide sufficient support for interbody fusion. This work demonstrated that PPF/PPF-DA networks are a suitable material for a biodegradable interbody fusion device as well as other load bearing orthopaedic implants.
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Liou, Yu-Ting, and 劉郁廷. "Establishment of Quality System Documents for Medical Device: Interbody Fusion Cage." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/85825431781784895211.

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碩士
國立臺灣科技大學
醫學工程研究所
105
With the rapid economic development and the improvement of health care quality, human demand for medical care is growing. Coupled with the problem of ageing population in Taiwan in recent years, the medical devices industry has become a star industry with great development potential. The establishment of medical devices regulations and supervision can guarantee safety and reduce risks when people using any sort of medical devices. In this thesis, it uses ISO 13485: 2003 medical devices quality management system and the standard model in Chapter Two of the third series of GMP (Good Manufacturing Practice) "medical devices manufacturing guidelines" as the main reference rules and regulations, and choose the interbody cage as the application of medical device product. The thesis researches into the establishment and maintenance of the quality system to ensure a series of complete operational specification process from research & development design, manufacturing, management, quality test validation, business side, final product launch to post market for product. There are operational specifications applicable to quality system documents for each process as references. By integrating overall requests of quality activities, we aim to reach expected quality standard and the objective of reliability within the established regulations. The thesis combines ISO 13485: 2003 and GMP regulations to develop quality system documents. The Level I Documentation:Quality Manual, Level II Documentation:Quality Procedure, Level III Documentation:Work Instruction and Level IV Documentation:Form/Record. They will be covered in detail in chapters. By actually establishing quality system of medical device company and participating in GMP audit process as the topic of this thesis, I have a better understanding of the quality system and accumulate practical experiences. Meanwhile, I am looking forward to implementing the maintenance of quality system and the spirit of supervision in the industry.
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Berry, Daniel J. "Functional imaging reveals modest strain concentrations associated with implant micromotion using modified BAK interbody cages." Thesis, 2003. http://hdl.handle.net/1957/32259.

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Interbody fusion cages are increasingly used in the treatment of spinal disease and injury in order to stabilize movement and promote arthrodesis of the vertebral bodies, but the micro-mechanics of the interaction between the cage and the adjacent host bone is not fully understood. This information has bearing on post-surgical therapy protocols, prediction of long-term bone tissue changes, and optimization of cage design. In order to gain insight into this problem, functional microCT imaging was used to directly evaluate implant micromotion and full-field vertebral body strains in an animal model implemented with various configurations of BAK interbody cages. It is believed that variations in cage design will produce variable implant success, functional fusion will be related to the extent of implant fixation, and specific strain fields will be associated with fused and unfused samples. We found that samples ranged from completely unfused (implant motion) to fully fused with organized trabecular bone (no motion). Strains concentrated at the implant interface in unfused samples, while fully fused samples exhibited uniformly distributed strains.
Graduation date: 2004
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Books on the topic "Interbody spinal fusion device"

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Goodrich, J. Allan, and Ildemaro J. Volcan. Extreme lateral interbody fusion (XLIF). 2nd ed. St. Louis, Mo: Quality Medical Pub., 2013.

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1926-, Lin Paul M., and Gill Kevin, eds. Lumbar interbody fusion. Rockville, Md: Aspen Publishers, 1989.

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Haid, Regis W. Lumbar Interbody Fusion Techniques. Edited by Regis Haid. QUALITY MEDICAL PUBLISHING, 2002.

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Allan, Goodrich J., and Volcan Ildemaro J, eds. Extreme lateral interbody fusion. St. Louis, Mo: Quality Medical Pub., 2008.

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Gala, Raj J., Lauren Szolomayer, and James Yue. Open Endoscopic Rhizotomy. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190626761.003.0015.

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The etiology of axial low back pain is multifactorial and includes pain arising from lumbar facet joints. The facet joints, capsules, and surrounding tissues are innervated by the medial branches of the dorsal rami. Rhizotomy of these nerves can provide pain relief in patients with lumbar facetogenic pain. The reported benefits of endoscopic approaches to the spine include minimal disruption of nonpathologic anatomy while simultaneously allowing for improved visualization of pathologic anatomy. Endoscopic techniques have been described for spinal stenosis, disc herniation, interbody fusion, infection, as well as dorsal medial branch rhizotomy. The goal of medial branch rhizotomy is to denervate lumbar facet joints that are contributing to axial back pain. The previous chapter focused on percutaneous techniques, while this chapter will describe endoscopic rhizotomy.
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Book chapters on the topic "Interbody spinal fusion device"

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Heary, Robert F., and John C. Quinn. "Transforaminal Lumbar Interbody Fusion." In Essentials of Spinal Stabilization, 239–49. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59713-3_20.

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Majeed, Gohar, and Farbod Asgarzadie. "Trans-sacral Lumbar Interbody Fusion." In Essentials of Spinal Stabilization, 413–27. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59713-3_31.

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Lin, Sen-Yuen, and Chun-Kwang Wu. "Anterior Interbody Fusion for Lumbar Spondylolisthesis." In Spinal Disorders in Growth and Aging, 279–86. Tokyo: Springer Japan, 1995. http://dx.doi.org/10.1007/978-4-431-66939-5_28.

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Burkus, J. K., K. T. Foley, and J. W. Haid, Jr. "Lumbar Interbody Fusion Using Bone Morphogenetic Protein: Results and Fusion Assessment." In Advances in Spinal Stabilization, 55–70. Basel: KARGER, 2003. http://dx.doi.org/10.1159/000072632.

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Kaiser, M. G., R. W. Haid, Jr., B. R. Subach, and G. E. Rodts, Jr. "Laparoscopic versus 'Mini-Open� Anterior Lumbar Interbody Fusion." In Advances in Spinal Stabilization, 277–89. Basel: KARGER, 2003. http://dx.doi.org/10.1159/000072649.

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Lewandrowski, Kai-Uwe, Joseph D. Gresser, Debra J. Trantolo, Georg Schollmeier, Frank Kandziora, and Donald L. Wise. "Development of a Bioresorbable Interbody Fusion Device." In Biomaterials Engineering and Devices: Human Applications, 215–22. Totowa, NJ: Humana Press, 2000. http://dx.doi.org/10.1007/978-1-59259-197-8_13.

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McEntee, Laurence, and Mario G. Zotti. "Lumbar Interbody Fusion Devices and Approaches: When to Use What." In Handbook of Spine Technology, 1–35. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-33037-2_85-1.

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McEntee, Laurence P., and Mario G. T. Zotti. "Lumbar Interbody Fusion Devices and Approaches: When to Use What." In Handbook of Spine Technology, 961–95. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-44424-6_85.

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Zhou, Yue, and Wenjie Zheng. "Endo-LIF: Spinal Interbody Fusion Under Endoscopic Guidance." In Endoscopic Procedures on the Spine, 291–98. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-10-3905-8_22.

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Jandhyala, Sean K., and Saad B. Chaudhary. "Open Transforaminal Lumbar Interbody Fusion with Posterior Spinal Instrumentation and Fusion." In The Resident's Guide to Spine Surgery, 135–43. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20847-9_16.

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Conference papers on the topic "Interbody spinal fusion device"

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Li, Lei, Zhaohua Chang, Xuelian Gu, and Chengli Song. "Design and Research of Interspinous Lumbar Non-Fusion Device." In ASME 2010 5th Frontiers in Biomedical Devices Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/biomed2010-32064.

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Objective: Long term clinical data showed that lumbar fusion for Lumbar spinal stenosis (LSS) and lumbar disc degeneration (LDD) therapy could change the loads of disc and articular facet and increase the motion of adjacent segments which lead to facet arthropathy and adjacent level degeneration. This study is to design and analyze an interspinous process device (IPD) that could prevent adjacent level degeneration in the LSS and LDD therapy. Method: The IPD was designed based on anatomical parameters measured from 3D CT images directly. The IPD was inserted at the validated finite element model of the mono-segmental L3/L4. The biomechanical performance of a pair of interbody fusion cages and a paired pedicel screws were studied to compare with the IPD. The model was loaded with the upper body weight and muscle forces to simulate five loading cases including standing, compression, flexion, extension, lateral bending and axial rotation. Results: The interbody fusion cage induced serious stress concentration on the surface of vertebral body, has the worst biomechanical performance among the three systems. Pedicle screws and interbody fusion cage could induce stress concentration within vertebral body which leads to vertebral compression fracture or screw loosening. Regarding to disc protection, the IPD had higher percentage to share the load of posterior lumbar structure than the pedicel screws and interbody fusion cage. Conclusion: IPD has the same loads as pedicle screw-rod which suggests it has a good function in the posterior stability. While the IPD had much less influence on vertebral body. Furthermore, IPD could share the load of intervertebral discs and facet joints to maintain the stability of lumbar spine.
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2

Bhatia, Nitin N., Kenneth H. Lee, Chris Bui, George M. Wahba, Allyson A. Estess, Mario Luna, and Thay Q. Lee. "Biomechanical Evaluation of an Expandable Cage in Single Segment Posterior Lumbar Interbody Fusion." In ASME 2009 4th Frontiers in Biomedical Devices Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/biomed2009-83047.

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One of the popular methods of treating lumbar spine pathologies involves a posterior lumbar interbody fusion (PLIF) using bilateral interbody non-expandable cages. Due to the geometry of these cages, they can require extensive bony removal and nerve root retraction. Some resultant risks of the procedure include dural lacerations and post-operative neuropraxia. Expandable interbody cages may address some of these concerns and possibly decrease the risks associated with PLIF procedures. This is the first study to our knowledge evaluating the biomechanical characteristics of an expandable lumbar interbody device in a cadaveric human spine model. The objective of this study was to evaluate the biomechanical characteristics of a new expandable interbody cage in single segment posterior lumbar interbody fusion using cadaveric lumbar spines.
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Gao, Robert X., Mathew E. Mitchell, and R. Scott Cowan. "Evaluation of Lumbar Spine Stabilization Using Anterior Interbody Fusion Cage." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33013.

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Spinal surgery uses a wide range of instrumentation devices to provide comfort to the patient, stabilize the spine, and enhance the bony healing process after surgery. In order to improve upon the effectiveness of these devices, the interaction between the spine and the implant devices needs to be studied from both medical and engineering perspectives. This paper investigates the effect of an anterior interbody fusion cage on lumbar spine stabilization, by means of numerical analysis using the finite element technique and experimental testing. Specifically, the relative displacement within an intact L4-L5 motion segment has been simulated and measured, under a range of compression, flexion, extension, torsion, and lateral bending loads. Subsequently, the effect of a single anterior lumbar fusion cage implanted into the segment was simulated and experimentally validated, under similar loading conditions. Comparison between the intact and cage-implanted segments indicated varying stabilizing ability of the fusion cage, which is highly dependent upon the cage position and the type of loading.
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4

DiAngelo, Denis J., Amanda L. Thomas, and Kevin T. Foley. "Biomechanical Comparison of Single-Level Cervical Plate Fusion and Interbody Cage Fusion." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32628.

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Anterior cervical graft fusion alone or supplemented with an anterior cervical plate instrumentation may be used to treat the diseased cervical spine. An anterior cervical plate is intended to restore the mechanical integrity of the operated spine and decrease graft complications. An alternative method to single-level graft fusion is to use an interbody fusion device. The objective of this study was to compare the biomechanical stability of a single-level graft-plated cervical construct with an interbody cage device.
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Gao, Robert X., Jonghyun Lee, Scott Cowan, and K. Francis Lee. "Comparative Study of Spine Fixation Technique." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-42195.

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Lumbar disc degeneration is an ailment that afflicts a large population. Spinal fusion techniques have been developed to alleviate pain and reestablish spine stability. It has been found that the stress levels within the vertebrae can significantly influence bone healing and resorption. To effectively apply fixation devices, analysis of the interactions between the tissue and inserted devices is needed. This paper presents a biomechanical study using the finite element (FE) method. Specifically, patient-based intact L4-L5 motion segments were constructed through an edge detection algorithm. Intervertebral disc was modeled with composite element. The effect of an anterior lumbar interbody fusion cage with unilaminar (ULFS) and translaminar facet screws (TLFS) was then evaluated. The results were analyzed in the terms of stability and stress distribution.
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DiAngelo, Denis J., Jason W. Sharp, Bobby J. McVay, Scott H. Kitchel, and Brian P. Kelly. "Comparison of Subsidence Failure Between a Cervical Cage and a Cortical Allograft in a Human Cadaveric Model." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33015.

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Interbody fusion (IBF) is an accepted procedure for the treatment of single-level cervical disc disease. The goal of interbody fusion in the cervical spine is to restore disc height and achieve solid arthrodesis; however, a concern with IBF devices is subsidence. The purpose of this study was to biomechanically test and compare subsidence between two cervical interbody fusion techniques, under axial compressive loading in a human cadaveric cervical model.
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Kiapour, A., A. M. Kiapour, H. Serhan, S. Garfin, T. Allen, and V. K. Goel. "Effect of Different Fixation Techniques on Segmental Kinematics and Load Sharing of Lumbar Spine: A FEM Study." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80882.

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Fusion has been the gold standard for treatment of various disorders associated with the spine especially at intervertebral disc level. The surgical procedure for fusion often requires fixation of the anterior column of the defected segment with interbody fixation devices such as cages. Anterior (ALIF), transforaminal (TLIF) and lateral (LIF) lumbar interbody fusion are some of the most common techniques for segmental fixation. The unacceptably low fusion rate with the interbody cages, when used as standalone, has led to the practice of combining these devices with posterior instrumentation. The segmental kinematics, the load distribution on the vertebral endplate and on the components of the posterior instrumentation are the key biomechanical parameters which can help to evaluate the performance of interbody fixation techniques with posterior instrumentation. We conducted a finite element (FE) study to compare biomechanics of these fixation methods.
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Tovar, Andre´s, Shawn E. Gano, John E. Renaud, and James J. Mason. "Topology and Shape Optimization of an Interbody Fusion Implant for Lumbar Spine Fixation." In ASME 2003 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/detc2003/dac-48851.

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The goal of this research is to obtain the optimum design of a new interbody fusion implant for use in lumbar spine fixation. A new minimally invasive surgical technique for interbody fusion is currently in development. The procedure makes use of an interbody implant that is inserted between two vertebral bodies. The implant is packed with bone graft material that fuses the motion segment. The implant must be capable of retaining bone graft and supporting spinal loads while fusion occurs. Finite element-based optimization techniques are used to drive the design. The optimization process is performed in two stages: topology optimization and then shape optimization. The different load conditions analyzed include: flexion, extension, and lateral bending.
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Khandha, Ashutosh D., Sasidhar S. Vadapalli, Scott A. Holekamp, Vijay K. Goel, Christopher M. Bono, and Steve R. Garfin. "Quantifying Motion Across a Solid Lumbar Interbody Fusion Using a Finite Element Model." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-42954.

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Clinical assessment of pseudarthrosis or solid fusion is based on the residual motion across the “fused” segment (Kowalski et al, 2001). Dynamic flexion/extension (F/E) radiographs are commonly used to determine residual motion. Despite widespread use, it is unclear what the appropriate “cut-off” criteria to declare a fusion solid should be, with recommendations ranging from 0 to 5°. These values have not been derived by scientific methods. The present study was initiated to predict the angular sagittal motion across simulated lumbar interbody fusions (IF) using a Finite Element Model (FEM) of the ligamentous lumbar spinal segment. Anterior and posterior lumbar interbody fusions were simulated at the L3–L4 level as per the clinical procedure. Varying degrees of fusion were taken into account and the fusion mass was the simulated as a cancellous core with a cortical shell. The results indicated that 0.5° to 5.14° of angular motion can occur depending on fusion location and degree of completeness. While continuous bone might be noted at surgical exploration, this amount of motion may enable persistent loading of remaining structures, such as the annulus or spinal ligaments. In our view, this may prompt a redefinition of clinically “solid fusion”.
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DiAngelo, Denis J., Geza Osztheimer, and Kevin T. Foley. "An Improved Testing Protocol for Evaluating Anterior Spinal Instrumentation Using Graft Loads in a Single-Level Cervical Discectomy or Corpectomy Model." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32629.

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Anterior cervical instrumentation used in discectomy or corpectomy graft fusion should restore the mechanical integrity of the operated spine and decrease graft complications. For fusion to occur, the spinal instrumentation must load-share with the interbody graft. Recent design changes in anterior cervical plates (ACP) aim to allow motion across the fusion site and load share with the graft [1]. However, existing American Society for Testing and Materials (ASTM) standards (F1717-96) for static and fatigue testing of spinal implant constructs in a corpectomy model do not include an interbody graft in the test method [2]. The objective of this study was to develop a non-destructive testing protocol and apparatus to rank the static and low-endurance performance of ACP instrumentation in single-level discectomy and corpectomy graft-plate models.
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