Academic literature on the topic 'Interleukin-4'

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Journal articles on the topic "Interleukin-4"

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Wu, Albert Y., Sanjiv Sur, J. Andrew Grant, and Julia W. Tripple. "Interleukin-4/interleukin-13 versus interleukin-5." Current Opinion in Allergy and Clinical Immunology 19, no. 1 (2019): 30–37. http://dx.doi.org/10.1097/aci.0000000000000490.

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&NA;. "Interleukin-4." Reactions Weekly &NA;, no. 606 (1996): 9. http://dx.doi.org/10.2165/00128415-199606060-00029.

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&NA;. "Interleukin-4." Reactions Weekly &NA;, no. 468 (1993): 8. http://dx.doi.org/10.2165/00128415-199304680-00038.

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&NA;. "Interleukin 4." Reactions Weekly &NA;, no. 399 (1992): 8. http://dx.doi.org/10.2165/00128415-199203990-00030.

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&NA;. "Interleukin 4." Reactions Weekly &NA;, no. 492 (1994): 8. http://dx.doi.org/10.2165/00128415-199404920-00033.

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Isakson, Peter. "Interleukin 4." Advances in Neuroimmunology 2, no. 1 (1992): 55–65. http://dx.doi.org/10.1016/s0960-5428(06)80005-7.

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Arreaza, Guillermo A., Mark J. Cameron, and Terry L. Delovitch. "Interleukin-4." Clinical Immunotherapeutics 6, no. 4 (1996): 251–60. http://dx.doi.org/10.1007/bf03259087.

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Jansen, J. H., W. E. Fibbe, R. Willemze, and J. C. Kluin-Nelemans. "Interleukin-4." Blut 60, no. 5 (1990): 269–74. http://dx.doi.org/10.1007/bf01736226.

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Banchereau, Jacques. "Interleukin 4." International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology 17, no. 7 (1990): 619–23. http://dx.doi.org/10.1016/0883-2897(90)90074-b.

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BRINCKMANN, Roland, Max S. TOPP, Ildikó ZALÁN, et al. "Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4." Biochemical Journal 318, no. 1 (1996): 305–12. http://dx.doi.org/10.1042/bj3180305.

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We have studied the expression of the 15-lipoxygenase gene in various permanent mammalian cell lines in response to interleukins-4 and -13, and found that none of the cell lines tested expressed 5-, 12- or 15-lipoxygenase when cultured under standard conditions. However, when the lung carcinoma cell line A549 was maintained in the presence of either interleukin for 24 h or more, we observed a major induction of 15-lipoxygenase, as indicated by quantification of 15-lipoxygenase mRNA, by immunohistochemistry, by immunoblot analysis and by enzyme activity assays. This effect was 15-lipoxygenase-s
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Dissertations / Theses on the topic "Interleukin-4"

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Silfverswärd, Carl-Johan. "Effects of Interleukin-4 and Interleukin-13 on Bone." Doctoral thesis, Uppsala University, Department of Surgical Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8414.

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<p>Cytokines play important roles in bone metabolism, participating in the complex interplay necessary for normal bone formation and turnover. The aim of the present thesis was to investigate the effects of two anti-inflammatory cytokines, interleukin-4 (IL-4) and interleukin-13 (IL-13) on bone. </p><p>Influence of pro- and anti-inflammatory cytokines on interleukin-6 (IL-6) formation in cultured human osteoblasts (hOBs) was investigated. IL-4 and IL-13 as well as interleukin-1 (IL-1) and tumour necrosis factor alpha and beta (TNF-α/β) stimulated IL-6 secretion in hOBs. Also, IL-4 and IL-13 sy
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Silfverswärd, Carl-Johan. "Effects of Interleukin-4 and Interleukin-13 on Bone /." Uppsala : Acta Universitatis Upsaliensis, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8414.

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Parker, Ruth E. "The rat interleukin-4 receptor." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318893.

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Traub, Benno [Verfasser]. "Einfluss der Interleukin-4-Interleukin-4-Rezeptor-Kaskade auf den malignen Phänotyp kultivierter Pankreaskarzinomzellen / Benno Traub." Ulm : Universität Ulm, 2017. http://d-nb.info/1140118161/34.

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Piehler, Daniel. "The inflammatory response against Cryptococcus neoformans is regulated by eosinophilic granulocytes and the interleukin-4/interleukin-4 receptor axis." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-78248.

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Cytokines play an important regulatory role during immune responses against pathogens. The outcome of an induced cytokine pattern is determined by many factors. It strongly depends on the nature of the pathogen and the host’s ability to control the quality and strength of cytokine signals. In pulmonary infection with Cryptococcus neoformans T helper (Th) 1 and Th17 cell subsets and their associated cytokines confer protection, whereas a Th2-biased response with production of interleukin (IL) -4 confers susceptibility. Since inappropriate Th responses often lead to death in immunosuppressed hum
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McKenzie, Grahame James. "Analysis of interleukin-13 and interleukin-4 function using gene targeting." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624953.

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Moga, Simona. "Bestimmung der Zytokine Interleukin-1α, Interleukin-1β, Interleukin-2, Interleukin-3 und Interleukin-4 im Vaginalsekret bei Frauen mit Bakterieller Dysbiose". Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-75888.

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Clarke, Christopher Jeremy Paul. "Molecular mechanisms of the anti-inflammatory cytokines interleukin-4 and interleukin-10." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285172.

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Alvi, Azra Johanna. "Heterogeneity of lymphokine-activated killer cells: Role of interleukin-2 and interleukin-4." Thesis, University of Ottawa (Canada), 1990. http://hdl.handle.net/10393/5579.

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Our main objective was to determine if the Lymphokine Activated Killer cells (LAK) activity is restricted to Natural Killer (NK) cells or if it is also detectable in T cell subsets, especially in CD3+ T cells that are also negative for CD4 and CD8 cell surface markers. We were able to obtain highly purified subsets of NK cells, helper/inducer (CD3+4+8$-$), suppressor/cytotoxic (CD3+4$-$8+) and double negative (CD3+4$-$8$-$) T cells. The double negative T cells are now known to be a subset of $\gamma\delta$-T cells. Highly purified subsets were obtained using antibody (sheep anti-mouse IgG) coa
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Schardt, Victor. "Vergleichende Untersuchungen zur Hefepilzbesiedelung von Mundhöhle und Vagina und Bestimmung von Interleukin-4, Interleukin-10 und Interleukin-12." Diss., lmu, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-155152.

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Books on the topic "Interleukin-4"

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1948-, Spits Hergen, ed. IL-4: Structure and function. CRC Press, 1992.

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Dohmann, Karen Brigitte. Expression, biochemische Charakterisierung und biologische Wirksamkeit der equinen Zytokine Interleukin 2 und Interleukin 4. [s.n.], 2000.

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Cuffe, Leonie M. Effect of moderate exercise induced stress on the Th1 (Interferon-gamma) and Th2 (Interleukin-4) cytokine subset response. University of Surrey Roehampton, 2001.

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1946-, Kluger Matthew J., Oppenheim Joost J. 1934-, and Powanda M. C, eds. The Physiologic, metabolic, and immunologic actions of interleukin-1: Proceedings of a symposium held in Ann Arbor, Michigan, June 4-6, 1985. Liss, 1985.

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Jankowski, Marek, and Tomasz Wandtke. Interleukin-27: Biological Properties and Clinical Application. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39664-4.

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Baggiolini, M. Interleukin-8 (Cytokines, Vol 4). S. Karger Publishers (USA), 1991.

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Ringshausen, Ingo. Induktion der common- [gamma] chain in nichthämatopoetischen Zellen durch Interleukin-4 und Interleukin-1. 2000.

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Köln, Universität zu, ed. Untersuchungen zur Funktion von Interleukin-4 und Interleukin-10: Herstellung und Analyse IL-4 und IL-10 defizienter Mäuse. 1993.

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Li, Weiqun. Analysen zur Beziehung zwischen der nicht-malignen Eigenschaft Interleukin 4-autokrin wachsender Zellen und der Antitumoraktivität von Interleukin 4. 1992.

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Feng, Ningping. Expression, charaterization and biological functions of interleukin-4 interleukin-13 receptor complexes in different cell types. 1997.

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Book chapters on the topic "Interleukin-4"

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Yokota, T., N. Arai, K. I. Arai, and A. Zlotnik. "Interleukin-4." In Peptide Growth Factors and Their Receptors I. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-49295-2_12.

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Farrar, William L. "Interleukin-4." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_3098-2.

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Yokota, T., N. Arai, K. I. Arai, and A. Zlotnik. "Interleukin-4." In Peptide Growth Factors and Their Receptors I. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-3210-0_12.

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Farrar, William L. "Interleukin-4." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_3098.

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Farrar, William L. "Interleukin-4." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_3098.

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Izuhara, Kenji, Shoichiro Ohta, Hiroshi Shiraishi, and Shoichi Suzuki. "Interleukin 4, Interleukin 13, and Interleukin 9." In Inflammation and Allergy Drug Design. Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444346688.ch13.

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Borish, Larry, and Jan M. Agosti. "Interleukin-4 Antagonism." In New Drugs for Asthma, Allergy and COPD. KARGER, 2001. http://dx.doi.org/10.1159/000062183.

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Sears, Alison, and Andrew Pink. "Interleukin-4/13 Inhibitors." In Handbook of Systemic Drug Treatment in Dermatology, 3rd ed. CRC Press, 2022. http://dx.doi.org/10.1201/9781003016786-19.

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Skevaki, Chrysanthi, Christoph Hudemann, and Harald Renz. "Interleukin 4 and the Related Cytokines (Interleukin 5 and Interleukin 13)." In Compendium of Inflammatory Diseases. Springer Basel, 2016. http://dx.doi.org/10.1007/978-3-7643-8550-7_158.

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Skevaki, Chrysanthi, Christoph Hudemann, and Harald Renz. "Interleukin 4 and the Related Cytokines (Interleukin 5 and Interleukin 13)." In Encyclopedia of Inflammatory Diseases. Springer Basel, 2014. http://dx.doi.org/10.1007/978-3-0348-0620-6_158-1.

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Conference papers on the topic "Interleukin-4"

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Tadjibayeva, K., and T. R. Romanovskaya. "REGULATORY ROLE OF INTERLEUKINS-4, 5 AND 6 IN THE DEVELOPMENT OF GLOMERULONEPHRITIS OF VARIOUS ETIOLOGIES." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-2-24-27.

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The relationship between the concentration of interleukin-4, 5, and 6 with the content of eosinophils and the level of C-reactive protein in patients with chronic glomerulonephritis was established. An increase in eosinophils was found in patients with chronic glomerulonephritis with a predominance of interleukin-4 compared with patients with a predominance of interleukin-5 and 6, which may be an important diagnostic marker of glomerulonephritis.
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Chaker, Adam, Iannis Hara, Kumar Mithilesh Jha, et al. "Interleukin-4 (IL-4) Rezeptor alpha Blockade schützt vor IL-4-bedingtem Geruchsverlust bei Mäusen." In 94. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1766938.

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Keenan, Christine R., Trudi Harris, and Alastair G. Stewart. "Tumour Necrosis Factor-±, Interleukin-4 And Interleukin-13 Impair Glucocorticoid Transactivation In Human Bronchial Epithelial Cells." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6678.

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Basyar, Masrul, and Sabrina Ermayanti. "Analysis on the Relationship Between Chronic Asthma Based on Spirometry, and Interleukin 4 and Interleukin 13." In Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia. EAI, 2019. http://dx.doi.org/10.4108/eai.13-11-2018.2283644.

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Chaker, Adam, Iannis Hara, Kumar Mithilesh Jha, et al. "Interleukin-4 (IL-4) receptor alpha blockade protects from IL-4 driven loss of smell in mice." In 94th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1767594.

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Atamas, Sergei P., Virginia Lockatell, Sachin Lavania, et al. "Expression And Functional Effects Of Alternatively Spliced Interleukin-4 In Asthma." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3934.

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DiTullio, A. E., S. Park, P. A. Torzilli, and C. T. Chen. "Cyclic Compression of Chondrocytes Counteracts Pro-Inflammatory Tissue Remodeling Induced by Interleukin-1." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193027.

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Chondrocytes in tissue engineered constructs face challenging environments when first transplanted into a synovial joint, including high levels of compression/shear and pro-inflammatory cytokines. The joint level of interleukin 1 (IL-1) after trauma injury and in a repaired joint is acutely elevated. Matrix remodeling in tissue engineered constructs can be easily affected by the elevation and activation of aggrecanases (ADAMTS-4 and ADAMTS-5) and matrix metalloproteinases (MMPs) [2–4, 7–9, 11]. Several recent studies suggest that tensile loading and unconfined compression of chondrocytes has s
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Venmar, Katherine T., Daniel G. Hwang, Ashley Dozier, Kathy J. Carter, Sareena Gillani, and Barbara Fingleton. "Abstract 5328: Interleukin-4 receptor regulates metastasis of mammary epithelial cancer cells." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5328.

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Hwang, Daniel G., Ashley Dozier, Kathy J. Carter, and Barbara Fingleton. "Abstract 2422: Epithelial interleukin-4 receptor promotes metastasis of mammary tumor cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-2422.

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Daulay, Milahayati, and Mutiara Indah Sari. "Interleukin-4 Gene Polymorphisms in Type 2 Diabetes Mellitus in Medan, Indonesia." In International Conference of Science, Technology, Engineering, Environmental and Ramification Researches. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0010078905750577.

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Reports on the topic "Interleukin-4"

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Fingleton, Barbara. Inhibition of Interleukin-4, a Survival Factor for Breast Cancer Cells, as an Antimetastatic Approach. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada542731.

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Fingleton, Barbara. Inhibition of Interleukin-4, a Survival Factor for Breast Cancer Cells, as an Antimetastatic Approach. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada555225.

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Chen, Yuhang, Jie Wang, Liqun Wu, Hong Chen, and Ziwei Zhang. Efficacy and safety of Chinese herbal medicines in the treatment of allergic rhinitis in children: a systematic review and meta-analysis based on randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0076.

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Review question / Objective: Population: Children (< 18 years) who were definitively diagnosed with allergic rhinitis were included, without concomitant other diseases. No limitation on location or gender. This study will only consider randomized controlled trials (RCTs) of Chinese herbal medicine for treating patients with allergic rhinitis. Other studies, such as animal studies, reviews, case reports, non-controlled studies, and quasi-RCTs, were not included. Comparison: The control intervention is based on allergic rhinitis treatment guidelines or placebo. Outcome: Primary outcomes: Nasal i
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นุชประยูร, สุรางค์. แผนการวิจัยเรื่อง การศึกษาภูมิคุ้มกันวิทยาเชิงลึกของโรคเท้าช้าง : มุ่งสู่การป้องกันภาวะเท้าช้างและการกำจัดโรคอย่างถาวร : รายงานการวิจัยฉบับสมบูรณ์. จุฬาลงกรณ์มหาวิทยาลัย, 2007. https://doi.org/10.58837/chula.res.2007.23.

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โรคเท้าช้าง (Lymphatic filariasis) เกิดจากหนอนพยาธิ 2 ชนิดหลักคือ Wuchereria bancrofti และ Brugia malayi ทางองค์การอนามัยโลกได้กำหนดให้โรคเท้าช้างเป็นโรคทางปรสิตที่ควรกำจัดให้หมดไปภายในปี พ.ศ. 2563 โดยมีแนวทางหลักในการควบคุมและป้องกันโรคเท้าช้างคือการจัดให้มีโปรแกรมการรักษาแบบหมู่ โดยให้ยา diethylcarbamazine (DEC) ร่วมกับยา albendazole แก่ประชากรในพื้นที่ที่มีความชุกของโรคสูง และการควบคุมพยาธิภาวะ ปัญหาที่สำคัญของการรักษาโรคเท้าช้างคือ การใช้ยา DEC ที่ก่อให้เกิดปฏิกิริยาหลังการรักษา กลไกของการเกิดพยาธิสภาพของโรคและการเกิดปฏิกิริยาหลังการรักษายังไม่เป็นที่ทราบแน่ชัดได้ จึงเป็นอุปสรรคที่สำคัญอย่
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ปาลกะ, ธนาภัทร. สารกดการกระตุ้นอินฟลามาโซมเพื่อบำบัดโรคอักเสบด้วยตนเอง : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2015. https://doi.org/10.58837/chula.res.2015.47.

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กลุ่มโรคที่เกิดจากการอักเสบด้วยตนเอง (autoinflammatory diseases) เป็นโรคที่เกิดจาการอักเสบที่ไม่เกิดร่วมกับการติดเชื้อมีหลากหลายรูปแบบ โดยเป็นกลุ่มโรคที่มีสาเหตุมาจากปัจจัยทางพันธุกรรมและ/หรือจากความผิดปกติของระบบเมแทบอลิสม โรคเก๊าท์ (gout) จัดเป็นโรคหนึ่งในกลุ่มโรคนี้ ซึ่งมีการตกตะกอนเป็นผลึกของเกลือยูเรต (monosodium urate) ที่เป็นผลมาจากการมีปริมาณกรดยูริกในเลือดสูงเกินปกติ สาเหตุหลักของอาการอักเสบเกิดจากการหลั่งไซโตไคน์ที่เกี่ยวข้องกับการอักเสบ โดยเฉพาะอินเตอร์ลิวคิน 1 บีต้า (interleukin 1 β; IL-1β) และอินเตอร์ลิวคิน 18 (IL-18) ผ่านการกระตุ้นอินฟลามาโซม (Inflammasome) อินฟลามาโซมเป็นสารประก
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Cao, Xianling, Xuanyou Zhou, Naixin Xu, Songchang Chang, and Chenming Xu. Association of IL-4 and IL-10 Polymorphisms with Preterm Birth Susceptibility: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0044.

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Review question / Objective: The aim of our systematic review and meta-analysis was to summarize the effects of IL-4 and IL-10 gene polymorphism and clarify their possible association with PTB. Condition being studied: World Health Organization (WHO) defines preterm birth (PTB) as babies born alive before 37 weeks of pregnancy are completed. The new estimates show that the prevalence of PTB during 2014 ranged from 8.7% to13.4% of all live births, about 15 million preterm babies born each year. Besides, PTB is the leading cause of death worldwide for children below 5 years of age. Babies born p
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Yu, Mei, Pengyu Wang, Binbin Li, et al. NRSF Negatively Regulates Microglial Pro-Inflammatory Activation. Progress in Neurobiology, 2024. http://dx.doi.org/10.60124/j.pneuro.2024.20.02.

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Microglial activation contributes to neurological disorders like Parkinson’s disease (PD), and modulating this activation is a potential therapeutic approach. The neuron-restrictive silencer factor (NRSF) functions as a negative regulator of gene transcription through epigenetic modifications. While previous research has primarily examined the role of NRSF in neuronal differentiation and injury, emerging evidence indicates that NRSF also plays a significant role in maintaining the phenotype of glial cells. In this study, we explored the role and underlying mechanisms of NRSF in lipopolysacchar
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Tumwasorn, Somying, and Versalovic, James. Identification of probiotic lactobacillus with anti-inflammatory activity in the gastrointestinal tract. Chulalongkorn University, 2009. https://doi.org/10.58837/chula.res.2009.15.

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In order to identify probiotic Lactobacillus for potential use as immunoprobiotics for the amelioration or treatment of inflammatory diseases in the gastrointestinal tract such as Helicobacter pylori-induced gastro-duodenal diseases and Clostridium difficile-associated disease (CDAD), we chose to test for the ability of human-derived Lactobacillus to modulate interleukin-8 (IL8) production in gastrointestinal epithelial cells. Eighty-seven gastric biopsy-derived Lactobacillus isolates were tested for their ability to modulate IL-8 production in H.pylori-stimulated AGS cells and 37 feces-derive
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Suksom, Daroonwan, Jettanong Klaewsongkram, Wannaporn Tongtako, and Nutdanai Jaronsukwimal. Effect of acute exercises, chronic exercise training and vitamin C supplementation on physiological change and symptoms in allegic rhinitis patients. Chulalongkorn University, 2013. https://doi.org/10.58837/chula.res.2013.72.

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The aim of this present study was to investigate an effect of acute exhaustive and moderate intensities exercises, exercise training and vitamin C supplementation on physiological change and rhinitis symptoms in allergic rhinitis patients. There were two studies: Study I : The subjects, aged18-45 years old, were divided into 2 groups: 14 healthy individuals and 13 allergic rhinitis (AR) patients. They were assigned to perform the strenuous exercise on treadmill by using Bruce protocol until they were exhausted. Two weeks later, they were assigned to perform a moderate exercise by walking on tr
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