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1

Tan, H. K., R. Bellomo, D. A. M'Pisi, and C. Ronco. "Phosphatemic Control during Acute Renal Failure: Intermittent Hemodialysis versus Continuous Hemodiafiltration." International Journal of Artificial Organs 24, no. 4 (2001): 186–91. http://dx.doi.org/10.1177/039139880102400403.

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Background Achieving “adequacy of dialysis” includes the maintenance of normal serum phosphate concentrations and is an important therapeutic goal in the treatment of acute renal failure (ARF). It is unknown whether this goal is best achieved with intermittent or continuous renal replacement therapy. Methods We compared the effects of continuous veno-venous hemodiafiltration (CVVHDF) and intermittent hemodialysis (IHD) on serum phosphate concentrations using daily morning blood tests in 88 consecutive intensive care patients half of which were treated with IHD and half with CRRT. Results Mean
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Clark, W. R., B. A. Mueller, K. J. Alaka, and W. L. Macias. "A comparison of metabolic control by continuous and intermittent therapies in acute renal failure." Journal of the American Society of Nephrology 4, no. 7 (1994): 1413–20. http://dx.doi.org/10.1681/asn.v471413.

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Azotemia control provided by blood pump-assisted continuous hemofiltration has not been rigorously compared with that provided by intermittent hemodialysis (IHD) for critically ill patients with acute renal failure (ARF). The metabolic control achieved by continuous venovenous hemofiltration (CVVH) and IHD was compared. In ARF patients treated with CVVH (N = 11), the normalized daily dose of therapy was 0.59 +/- 0.23 (mean +/- SD) and the normalized protein catabolic rate was 1.82 +/- 0.95 g/kg per day. The serum urea nitrogen concentration (SUN) declined with CVVH from an initial value of 114
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3

Gaiki, Meghana R., Maria V. DeVita, Jordan L. Rosenstock, Georgia Panagopoulos, and Michael F. Michelis. "96: Adequacy of Intermittent Hemodialysis (IHD) in an Inpatient Setting." American Journal of Kidney Diseases 55, no. 4 (2010): B55. http://dx.doi.org/10.1053/j.ajkd.2010.02.103.

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4

Bunz, Hanno, Otto Tschritter, Michael Haap, Reimer Riessen, Nils Heyne, and Ferruh Artunc. "Elimination of Contrast Agent Gadobutrol with Sustained Low Efficiency Daily Dialysis Compared to Intermittent Hemodialysis." Kidney and Blood Pressure Research 44, no. 6 (2019): 1363–71. http://dx.doi.org/10.1159/000502960.

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Background: In patients with renal failure, gadolinium-based contrast agents (GBCA) can be removed by intermittent hemodialysis (iHD) to prevent possible toxic effects. There is no data on the efficacy of GBCA removal via sustained low efficiency daily dialysis (SLEDD) which is mainly used in intensive care unit (ICU) patients. Methods: We compared the elimination of the GBCA gadobutrol in 6 ICU patients treated with SLEDD (6–12 h, 90 L dialysate) with 7 normal ward inpatients treated with iHD (4 h, dialysate flow 500 mL/min). Both groups received 3 dialysis sessions on 3 consecutive days star
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5

Simour, Aïcha, Tarek Dendane, Khalid Abidi, et al. "Evaluation of intermittent hemodialysis conducted off-site on patients with renal insufficiency admitted in the intensive care unit of a developing country." International Journal of Research in Medical Sciences 7, no. 2 (2019): 410. http://dx.doi.org/10.18203/2320-6012.ijrms20190344.

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Background: In most developing countries, the renal replacement therapy (RRT) in ICU is not performed locally. We designed this study to assess the intermittent hemodialysis (IHD) offsite intakes on survival in critically ill patients admitted with renal failure.Methods: We prospectively analyzed all patients admitted to medical ICU with Acute Renal Failure (AKF) or Chronic Renal Failure (CKF) from February 2011 to September 2013. Patients were divided into two groups: those that received IHD in Hemodialysis Unit (IHD+) and those who did not (IHD-). Every patient IHD+ was matched to a patient
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6

Grzegorzewska, A. E., and W. Banachowicz. "Results of improvement in adequacy of intermittent hemodialysis (IHD) in uremic patients." Hemodialysis International 9, no. 1 (2005): 96. http://dx.doi.org/10.1111/j.1492-7535.2005.1121bt.x.

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7

Manns, M., M. H. Sigler, and B. P. Teehan. "RENAL FUNCTION CHANGES DURING INTERMITTENT HEMODIALYSIS (IHD) VERSUS CONTINUOUS HEMODIALYSIS (CWHD) IN ACUTE RENAL FAILURE (ARF)." ASAIO Journal 42, no. 2 (1996): 78. http://dx.doi.org/10.1097/00002480-199603000-00292.

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8

Manns, M., M. H. Singer, and B. P. Teehan. "RENAL FUNCTION CHANGES DURING INTERMITTENT HEMODIALYSIS (IHD) VERSUS CONTINUOUS HEMODIALYSIS (CVVHD) IN ACUTE RENAL FAILURE (ARF)." ASAIO Journal 42, no. 2 (1996): 78. http://dx.doi.org/10.1097/00002480-199604000-00293.

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9

Hoff, Brian M., Jenana H. Maker, William E. Dager, and Brett H. Heintz. "Antibiotic Dosing for Critically Ill Adult Patients Receiving Intermittent Hemodialysis, Prolonged Intermittent Renal Replacement Therapy, and Continuous Renal Replacement Therapy: An Update." Annals of Pharmacotherapy 54, no. 1 (2019): 43–55. http://dx.doi.org/10.1177/1060028019865873.

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Objective: To summarize current antibiotic dosing recommendations in critically ill patients receiving intermittent hemodialysis (IHD), prolonged intermittent renal replacement therapy (PIRRT), and continuous renal replacement therapy (CRRT), including considerations for individualizing therapy. Data Sources: A literature search of PubMed from January 2008 to May 2019 was performed to identify English-language literature in which dosing recommendations were proposed for antibiotics commonly used in critically ill patients receiving IHD, PIRRT, or CRRT. Study Selection and Data Extraction: All
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10

Kwizera, Arthur, Janat Tumukunde, Lameck Ssemogerere, et al. "Clinical Characteristics and 30-Day Outcomes of Intermittent Hemodialysis for Acute Kidney Injury in an African Intensive Care Unit." BioMed Research International 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/2015251.

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Introduction. Acute kidney injury (AKI) is a common occurrence in the intensive care unit (ICU). Studies have looked at outcomes of renal replacement therapy using intermittent haemodialysis (IHD) in ICUs with varying results. Little is known about the outcomes of using IHD in resource-limited settings where continuous renal replacement therapy (CRRT) is limited. We sought to determine outcomes of IHD among critically ill patients admitted to a low-income country ICU.Methods. A retrospective review of patient records was conducted. Patients admitted to the ICU who underwent IHD for AKI were in
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11

Manns, M., M. H. Sigler, and B. P. Teehan. "Management of acute renal failure (ARF) with continuous veno-venous hemodialysis (CVVHD) or intermittent hemodialysis (IHD): A comparative analysis." Intensive Care Medicine 22, S1 (1996): S41. http://dx.doi.org/10.1007/bf01921215.

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12

Klarenbach, Scott, Braden Manns, Neesh Pannu, Fiona M. Clement, Natasha Wiebe, and Marcello Tonelli. "Economic evaluation of continuous renal replacement therapy in acute renal failure." International Journal of Technology Assessment in Health Care 25, no. 03 (2009): 331–38. http://dx.doi.org/10.1017/s0266462309990134.

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Objectives:Controversy exists regarding the optimal method of providing dialysis in critically ill patients with acute renal failure. We sought to determine the cost-effectiveness of treatment strategies.Methods:Adult subjects requiring renal replacement therapy in a critical care setting who are candidates for intermittent hemodialysis (IHD) or continuous renal replacement therapy (CRRT) were considered within a Markov model. Alternative strategies including IHD, and standard or high dose CRRT were compared. The model considered relevant clinical and economic outcomes, and incorporated data o
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13

Fedorenko, Marianna, Simon W. Lam, Lisa M. Harinstein, Elizabeth A. Neuner, Sevag Demirjian, and Seth R. Bauer. "Compliance With Institutional Antimicrobial Dosing Guidelines in Patients Receiving Continuous Venovenous Hemodialysis." Journal of Pharmacy Practice 28, no. 4 (2014): 380–86. http://dx.doi.org/10.1177/0897190013519679.

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Objective: Describe the rate of compliance with institutional antimicrobial dosing guidelines in patients on concomitant continuous venovenous hemodialysis (CVVHD). Methods: This single-center retrospective chart review evaluated adult patients receiving concomitant intravenous antimicrobials and CVVHD for at least 24 hours over a 2-month period. Results: A total of 42 patients, 76 antimicrobial courses, and 208 study days (24 hours of concomitant therapy) were evaluated. Overall, antimicrobials were dosed according to the institutional guidelines on 162 (78%) of 208 study days. All nonconcord
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14

VANHOLDER, RAYMOND, WIM VAN BIESEN, and NORBERT LAMEIRE. "What Is the Renal Replacement Method of First Choice for Intensive Care Patients?" Journal of the American Society of Nephrology 12, suppl 1 (2001): S40—S43. http://dx.doi.org/10.1681/asn.v12suppl_1s40.

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Abstract.Renal replacement therapy for the patient with acute renal failure on the intensive care unit can be offered in several different formats: intermittent hemodialysis (IHD), continuous renal replacement therapy (CRRT), and slow low-efficient daily dialysis (SLEDD). It is frequently claimed that CRRT offers several advantages over IHD, but most of these, such as correction of metabolic acidosis, better recovery of renal function, better clinical outcome due to application of biocompatible dialysis membranes, correction of malnutrition, and better removal of cytokines, are not corroborate
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15

Brucculeri, Michael, Wesley Gabbard, John Masson, and Nuruddin Jooma. "Simultaneous Double Hemodialysis for the Control of Refractory Hyperammonemia." International Journal of Artificial Organs 36, no. 2 (2013): 135–38. http://dx.doi.org/10.5301/ijao.5000177.

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Introduction In adults, hyperammonemia is generally associated with hepatic dysfunction or as a complication of urinary diversions when infected or obstructed. Hyperammonemia has also rarely been reported in association with multiple myeloma. With modest elevations, hyperammonemia often leads to encephalopathy. However, when ammonia reaches extreme levels cerebral edema and herniation may occur leading to coma, seizures, or death. Case We describe a 72-year-old Caucasian male with a history of end-stage renal disease (ESRD) and multiple myeloma who developed profound encephalopathy and eventua
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Coritsidis, George, Andrew Chao, Dharmesh Sutariya, Alan Hola, Sudhanshu Jain, and Yiannis Apergis. "70 Sustained Low Efficiency Daily Dialysis (SLEDD) in the ICU: Outcomes Compared to Intermittent Hemodialysis (IHD)." American Journal of Kidney Diseases 57, no. 4 (2011): B34. http://dx.doi.org/10.1053/j.ajkd.2011.02.073.

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17

Yee, Jason, Patricia Saunders-Hao, Leandra Miko, and Meenakshi Rana. "1702. Assessing the Safety and Efficacy of Valganciclovir Dosing for Cytomegalovirus Prophylaxis in Solid Organ Transplant Recipients on Hemodialysis." Open Forum Infectious Diseases 7, Supplement_1 (2020): S833—S834. http://dx.doi.org/10.1093/ofid/ofaa439.1880.

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Abstract Background Valganciclovir is the standard of care used for the prevention of Cytomegalovirus (CMV) infections among solid organ transplant (SOT) recipients. Currently there is minimal guidance for prophylaxis in SOT recipients undergoing intermittent hemodialysis (IHD). At Mount Sinai Hospital (MSH), the current practice for CMV prophylaxis in SOT recipients on IHD is valganciclovir 450 mg every other day (Q48H) or three-times weekly (TIW). This study aims to evaluate the safety and effectiveness of these dosing regimens in SOT recipients on IHD. Methods A single-center, retrospective
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18

Tsu, Laura V., and William E. Dager. "Bivalirudin Dosing Adjustments for Reduced Renal Function with or Without Hemodialysis in the Management of Heparin-Induced Thrombocytopenia." Annals of Pharmacotherapy 45, no. 10 (2011): 1185–92. http://dx.doi.org/10.1345/aph.1q177.

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Background: While not approved by the Food and Drug Administration for treatment of heparin-induced thrombocytopenia (HIT), except in patients undergoing percutaneous interventions, the direct thrombin inhibitor bivalirudin is a treatment option that is gaining use. An initial dose of bivalirudin 0.15–0.2 mg/kg/h, adjusted to an activated partial thromboplastin time (aPTT) of 1.5–2.5 times the baseline value, has been suggested. Initial dosing in patients with renal dysfunction, including those on hemodialysis, is unclear. Objective: To evaluate initial bivalirudin dosing requirements in patie
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19

Hermez, Klodia, and Carla Dudash-Mion. "Profound Metabolic Acidosis due to Metformin Intoxication Requiring Dialysis." Case Reports in Nephrology 2021 (May 24, 2021): 1–5. http://dx.doi.org/10.1155/2021/9914982.

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Metformin-associated lactic acidosis (MALA) is a rare but life-threatening condition with often high mortality rates. Despite this, metformin continues to be one of the most commonly prescribed antihyperglycemic agents in the market. We present a unique case of a 61-year-old female with severe acidosis of pH = 6.72 and lactic acid of 26 mmol/L who presented obtunded after ingestion of an unknown amount of metformin. She was subsequently intubated, became hypotensive, and was initiated on vasopressors. She was swiftly started on a combination of intermittent hemodialysis (IHD) and bicarbonate t
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Gašparović, Vladimir, Ina Filipović-Grčić, Marijan Merkler, and Zoran Pišl. "Continuous Renal Replacement Therapy (CRRT) or Intermittent Hemodialysis (IHD)—What Is the Procedure of Choice in Critically Ill Patients?" Renal Failure 25, no. 5 (2003): 855–62. http://dx.doi.org/10.1081/jdi-120024300.

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21

Tao, Yiying, and Wenbo Hu. "Comparative Study of Chronic Renal Failure Patients' Efficacy Between Sustained Low-efficiency Daily Dialysis (SLEDD) and Intermittent Hemodialysis (IHD)." Hong Kong Journal of Nephrology 17, no. 2 (2015): S130. http://dx.doi.org/10.1016/j.hkjn.2015.09.218.

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22

Allegretti, Andrew S., Paul Endres, Tyler Parris, et al. "Accelerated Venovenous Hemofiltration as a Transitional Renal Replacement Therapy in the Intensive Care Unit." American Journal of Nephrology 51, no. 4 (2020): 318–26. http://dx.doi.org/10.1159/000506412.

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Background: Continuous renal replacement therapy (CRRT) is commonly employed in the intensive care unit (ICU), though there are no guidelines around the transition between CRRT and intermittent hemodialysis (iHD). Accelerated venovenous hemofiltration (AVVH) is a modality utilizing higher hemofiltration rates (4–5 L/h) with shorter session durations (8–10 h) to “accelerate” the clearance and volume removal that normally is spread out over a 24-h period in CRRT. We examined AVVH as a transition therapy between CRRT and iHD, with the aim of decreasing time on CRRT and providing a more graduated
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Iqbal, S., MM Iqbal, MO Faruq, K. Fatema, and WMM Haque. "MP513OUTCOME OF PERITONEAL DIALYSIS (PD) IN CRITICALLY ILL PATIENTS AS AN ALTERNATIVE TO INTERMITTENT HEMODIALYSIS (IHD) AND SLOW LOW EFFICIENCY DIALYSIS (SLED)." Nephrology Dialysis Transplantation 31, suppl_1 (2016): i510—i511. http://dx.doi.org/10.1093/ndt/gfw195.29.

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24

Clark, W. R., B. A. Mueller, M. A. Kraus, and W. L. Macias. "Extracorporeal therapy requirements for patients with acute renal failure." Journal of the American Society of Nephrology 8, no. 5 (1997): 804–12. http://dx.doi.org/10.1681/asn.v85804.

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Renal replacement therapy (RRT) requirements for critically ill patients with acute renal failure (ARF) depend on numerous factors, including the degree of hypercatabolism, patient size, and desired level of metabolic control. However, the current practice at many institutions is to prescribe generally similar amounts of RRT to ARF patients essentially without regard for the above factors. In this study, a computer-based model designed to permit individualized RRT prescription to ARF patients was developed. The critical input parameter is the desired level of metabolic control, which is the ti
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Iqbal, Sarwar, and Mohammad Omar Faruq. "Renal Replacement Therapy in Critically Ill: Current Trend and New Direction." Bangladesh Critical Care Journal 3, no. 1 (2015): 17–21. http://dx.doi.org/10.3329/bccj.v3i1.24096.

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Critically ill patients often present with renal dysfunction. Acute kidney injury (AKI) is common in intensive care unit (ICU) patients and is often a component of multiple organ dysfunction syndrome (MODS). Renal replacement therapy (RRT) plays a significant role in management of acute and chronic renal failure in ICU. During the last decade RRT has made remarkable progress in management of renal dysfunction of critically ill. The Acute Dialysis Quality Initiative conceived in 2002 proposed RIFLE classification for AKI (risk, injury, failure, loss, end-stage kidney disease) using serum creati
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Iqbal, Sarwar, Tufayel Ahmed Chowdhury, Mohammad Omar Faruq, et al. "Emergency Continuous Peritoneal Dialysis using Flexible Tenckhoff Catheter inserted with Reinforced Purse String Suture : An efficient substitute of renal replacement therapy in Critically Ill Patients with AKI when Intermittent Hemodialysis, Sustained lo." Bangladesh Critical Care Journal 4, no. 1 (2016): 3–8. http://dx.doi.org/10.3329/bccj.v4i1.27970.

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Introduction : Renal replacement therapy (RRT) is often used to treat critically ill patients associated with acute or chronic renal failure. Peritoneal dialysis (PD) is an option when intermittent hemodialysis (IHD), sustained low efficiency dialysis (SLED) or Continuous renal replacement therapy (CRRT) are not feasible. PD customarily uses rigid catheter and cannot be used for more than 3 days as there is increased chance of infection and it can cause perforation of hollow viscera and often there is hemorrhage due to trauma to the adjacent organs. In this study we used Tenckhoff flexible PD
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Kunka, Megan E., Elizabeth A. Cady, Heejung C. Woo, and Melissa L. Thompson Bastin. "Flucytosine Pharmacokinetics in a Critically Ill Patient Receiving Continuous Renal Replacement Therapy." Case Reports in Critical Care 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/927496.

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Purpose. A case report evaluating flucytosine dosing in a critically ill patient receiving continuous renal replacement therapy.Summary. This case report outlines an 81-year-old male who was receiving continuous venovenous hemofiltration (CVVH) for acute renal failure and was being treated with flucytosine for the treatment of disseminatedCryptococcus neoformansinfection. Due to patient specific factors, flucytosine was empirically dose adjusted approximately 50% lower than intermittent hemodialysis (iHD) recommendations and approximately 33% lower than CRRT recommendations. Peak and trough le
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Jörres, A. "Extracorporeal Treatment Strategy in Acute Renal Failure." International Journal of Artificial Organs 25, no. 5 (2002): 391–96. http://dx.doi.org/10.1177/039139880202500508.

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The mortality of acute renal failure remains high (around 50–70%) despite manifold improvements in terms of techniques and equipment for renal replacement therapies as well as patient monitoring and intensive care support. At present, it is not clear if the method chosen for renal replacement therapy, i.e. intermittent hemodialysis or continuous hemofiltration, might impact on the outcome of these patients. Whilst earlier retrospective studies suggested that CVVH might result in better survival and renal recovery in acute patients, recent prospective studies indicated that this may not be the
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Kassay, Andrea Danielle, Alexander Adibfar, and Robert Cartotto. "16 Sustained Low Efficiency Dialysis (SLED) in Burn Patients with Acute Kidney Injury." Journal of Burn Care & Research 42, Supplement_1 (2021): S16—S17. http://dx.doi.org/10.1093/jbcr/irab032.021.

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Abstract Introduction Acute Kidney Injury (AKI) is common among patients with major burns and may require treatment with renal replacement therapy (RRT). Although continuous renal replacement therapy (CRRT) modalities are widely used and offer many advantages over traditional intermittent hemodialysis (IHD), CRRT is expensive, labour-intensive, and may not be available in some burn centers. Sustained Low Efficiency Dialysis (SLED) is a moderately efficient alternative to IHD, but its use in burn patients with AKI has not been described. The purpose of this study was to review our experience wi
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Kline, Ellen G., Minh Hong T. Nguyen, Erin K. McCreary, et al. "1298. Population Pharmacokinetics of Ceftazidime-avibactam among Critically-ill Patients with and without Receipt of Continuous Renal Replacement Therapy." Open Forum Infectious Diseases 7, Supplement_1 (2020): S663—S664. http://dx.doi.org/10.1093/ofid/ofaa439.1481.

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Abstract Background Ceftazidime-avibactam (CAZ-AVI) is used to treat multidrug-resistant infections. There are limited pharmacokinetic (PK) data among critically-ill patients (pts) and no dosing recommendations for those receiving continuous renal replacement therapy (CRRT). Methods We conducted a PK study of CAZ-AVI among pts with and without CRRT. Serial blood samples were collected at 0 (pre-dose), 2, 4, 6, and 8 hours after CAZ-AVI administration. All doses were infused over 2h. Samples were centrifuged and plasma stored at -80°C until analysis by a Shimadzu Nexera XD UHPLC with a Shimadzu
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Melchert, Alessandra, Silvano Salgueiro Geraldes, André Nanny Le Sueur Vieira, et al. "Intermittent hemodialysis in dogs with chronic kidney disease stage III." Ciência Rural 47, no. 10 (2017). http://dx.doi.org/10.1590/0103-8478cr20160900.

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ABSTRACT: Intermittent hemodialysis (IHD) is a form of renal replacement that is used in veterinary medicine for cases involving drug removal, electrolyte imbalance, acute kidney injury, and chronic kidney disease (CKD). The aim of the present study was to verify the efficacy of IHD in dogs with CKD staged at grade III and to evaluate the effect of IHD on quality of life. Twelve dogs with CKD at stage III met the inclusion criteria and were divided equally into two groups. The control group (n=6) received only clinical treatment and intravenous fluid therapy, and the hemodialysis group (n=6) r
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Shah, Sunish, David P. Nicolau, Dayna McManus, and Jeffrey E. Topal. "A Novel Dosing Strategy of Ceftolozane/Tazobactam in a Patient Receiving Intermittent Hemodialysis." Open Forum Infectious Diseases 8, no. 6 (2021). http://dx.doi.org/10.1093/ofid/ofab238.

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Abstract We describe the case of a 54-year-old male receiving intermittent hemodialysis (iHD) who was found to have Pseudomonas aeruginosa bacteremia secondary to osteomyelitis of the calcaneus bone. The patient was clinically cured without recurrence using a ceftolozane/tazobactam (CTZ) dosing strategy of 100/50 mg every 8 hours (standard dosing) and 1000/500 mg thrice weekly following iHD. Utilizing a susceptibility breakpoint of ≤4 µg/mL for P. aeruginosa, the T > MIC for standard dosing and the 1000/500-mg thrice-weekly following iHD regimen were calculated to be 92.7% and 94.1%, re
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Ghoshal, Shivani, Nathaniel O’Connell, Charles Tegeler, and Barry I. Freedman. "Cerebral hemodynamics in peritoneal dialysis versus intermittent hemodialysis: A transcranial Doppler pilot study." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, September 10, 2020, 089686082095371. http://dx.doi.org/10.1177/0896860820953712.

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This study evaluated intradialytic cerebral hemodynamics measured by transcranial Doppler (TCD) in intermittent hemodialysis (iHD) versus nightly peritoneal dialysis (NIPD). Intradialytic TCD was serially performed in chronic dialysis patients receiving iHD ( n = 10) and NIPD ( n = 10). A linear mixed model was used to model mean flow velocity (MFV), pulsatility index (PI), and mean arterial pressure (MAP) as functions of time and treatment group. Intradialytic cerebral volatility (IDCV) was calculated using the coefficient of variation (CV) and mean absolute value of change (AVC) of each pati
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Moranne, Olivier, Sylvain Cariou, Ziyad Messikh, et al. "MO657RANDOMIZED CONTROL TRIAL OF INTERMITTENT HEMODIALYSIS WITH REGIONAL CITRATE VS PRIMING HEPARIN WITH PREDILUTION IN PATIENTS AT RISK OF BLEEDING." Nephrology Dialysis Transplantation 36, Supplement_1 (2021). http://dx.doi.org/10.1093/ndt/gfab099.002.

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Abstract Background and Aims Standard intermittent haemodialysis (SIHD) includes anticoagulation to avoid clotting of the dialysis system. In patients at high risk for bleeding, alternativ methods have been developed to avoid systemic anticoagulation. Regional citrate anticoagulation (RCA) is usually used with continuous renal replacement therapy and low blood flow but the Promotheus® device (Freseinus Medical care-Germany) allow RCA for liver support therapy with dialysis system 4008H® and blood flow over 200ml/min. The aim of this study was to compare the IHD with RCA (IHD-RCA) to SIHD witho
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Sun, Lu Xuan (Lisa), Kang-Wei (David) Liu, Stephanie Lynch, Mielen Mistry, Heather Wise, and Eduard Iliescu. "Validation of a Weight Threshold–Based Vancomycin Dosing Protocol for Patients Undergoing Intermittent Hemodialysis." Canadian Journal of Hospital Pharmacy 72, no. 5 (2019). http://dx.doi.org/10.4212/cjhp.v72i5.2930.

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ABSTRACTBackground: Patients receiving intermittent hemodialysis (IHD) are at high risk of acquiring gram-positive infections, which are often treated with IV vancomycin. Despite frequent use of vancomycin in the IHD setting, there is variability in dosing and monitoring practices among clinicians at the study institution. There is also a paucity of evidence regarding optimal vancomycin dosing to achieve target pre-IHD serum concentration. Objectives: The primary objective was to compare the percentage of treatment courses with a serum vancomycin concentration between 15 and 20 mg/L, measured
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Leroy, Christophe, Bruno Pereira, Edouard Soum, et al. "Comparison between regional citrate anticoagulation and heparin for intermittent hemodialysis in ICU patients: a propensity score-matched cohort study." Annals of Intensive Care 11, no. 1 (2021). http://dx.doi.org/10.1186/s13613-021-00803-x.

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Abstract Background Regional citrate anticoagulation (RCA) is the gold standard of anticoagulation for continuous renal replacement therapy but is rarely used for intermittent hemodialysis (IHD) in ICU. Few studies assessed the safety and efficacy of RCA during IHD in ICU; however, no data are available comparing RCA to heparin anticoagulation, which are commonly used for IHD. The aim of this study was to assess the efficacy and safety of RCA compared to heparin anticoagulation during IHD. Methods This retrospective single-center cohort study included consecutive ICU patients treated with eith
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Parapiboon, Watanyu, Thosapol Chumsungnern, and Treechada Chamradpan. "Peritoneal dialysis with a lower dosage versus conventional intermittent hemodialysis in acute kidney injury: A propensity-matched study." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, November 28, 2020, 089686082097085. http://dx.doi.org/10.1177/0896860820970851.

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Background: Literature regarding the outcomes of lower dosage peritoneal dialysis (PD) in treating acute kidney injury (AKI) among resource-limited setting is sparse. This study aims to compare the risk of mortality in patients with AKI receiving lower PD dosage and conventional intermittent hemodialysis (IHD) in Thailand. Methods: In a tertiary center in Thailand, a matched case–control study using propensity scores in patients with AKI was conducted to compare the outcomes between lower PD dosage (18 L per day for first two sessions, weekly Kt/ V 2.2) and IHD (three times a week) from Februa
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Mina-Cuaño, Patricia Maria Gregoria, Cary Amiel G. Villanueva, John Jefferson V. Besa, et al. "Which dialysis method should be used for patients with COVID-19?" Acta Medica Philippina 54 (August 20, 2020). http://dx.doi.org/10.47895/amp.v54i0.1873.

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KEY FINDINGS• Very low-quality evidence from a single retrospective study suggests that continuous renal replacementtherapy (CRRT) may reduce mortality among COVID-19 patients on invasive mechanical ventilation. Guidelinesrecommend CRRT for critically ill patients to minimize the risk of possible transmission, if this option is available.• Although uncommon, acute kidney injury (AKI) can occur in association with coronavirus disease 2019(COVID-19) and is associated with increased in-hospital mortality.• There are currently no published or ongoing clinical trials directly comparing dialysis mod
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Melo, Erica, Marcelo Silveira, Fábio Dutra, et al. "P1076HEMODYNAMIC TOLERANCE TO INTERMITTENT DIALYSIS IN CRITICALLY ILL PATIENTS: THE CLINICAL JUDGMENT OF HIPERVOLEMIA IS ABLE TO PREDICATIT?" Nephrology Dialysis Transplantation 35, Supplement_3 (2020). http://dx.doi.org/10.1093/ndt/gfaa142.p1076.

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Abstract Background and Aims Evaluation and management of fluid balance are a key challenge in caring for the critically ill requiring renal replacement therapy. As intradialytic hypotension is a common complication and can be associated ultrafiltration rate. Usually the nephrologist and critical care physician have relied in their subjective clinical judgment and clinical data to calculate ultrafiltration. The aim of this study was to assess the prediction of clinical judgment of fluid overload and other clinical and dialysis data as predictors of hemodynamic tolerance to intermittent dialysi
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Macedo, Etienne, Bethany Karl, Euyhyun Lee, and Ravindra L. Mehta. "A randomized trial of albumin infusion to prevent intradialytic hypotension in hospitalized hypoalbuminemic patients." Critical Care 25, no. 1 (2021). http://dx.doi.org/10.1186/s13054-020-03441-0.

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Abstract Background Intradialytic hypotension (IDH) is a frequent complication of intermittent hemodialysis (IHD), occurring from 15 to 50% of ambulatory sessions, and is more frequent among hospitalized patients with hypoalbuminemia. IDH limits adequate fluid removal and increases the risk for vascular access thrombosis, early hemodialysis (HD) termination, and mortality. Albumin infusion before and during therapy has been used for treating IDH with the varying results. We evaluated the efficacy of albumin infusion in preventing IDH during IHD in hypoalbuminemic inpatients. Methods A randomiz
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"17 Hemodynamic Effects of Intermittent Hemodialysis (iHD) on a Patient with Left Ventricular Assist Device (LVAD): A Case Report." American Journal of Kidney Diseases 73, no. 5 (2019): 646. http://dx.doi.org/10.1053/j.ajkd.2019.03.019.

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"Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD)." Case Medical Research, September 18, 2019. http://dx.doi.org/10.31525/ct1-nct04094064.

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Kohn, Orly F., Miguel Plascencia, Yolanda Taylor, and Jay L. Koyner. "Novel use of premixed dialysate bags during water supply interruption in acute hospital setting." Kidney360, December 9, 2020, 10.34067/KID.0004762020. http://dx.doi.org/10.34067/kid.0004762020.

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Dialysis patients are exposed to large amounts of water during conventional intermittent hemodialysis (IHD) hence strict regulations exist for the quality of water used to prepare dialysate. Occasionally water systems fail due to natural disasters or structural supply issues such as water main breaks or unplanned changes in municipal or facility water quality. It is critical to regularly monitor and immediately recognize such a failure and take steps to avoid exposing the patients to contaminants. In addition to the recognition of the problem, the ability to pivot and continue to provide safe
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Naorungroj, Thummaporn, Fumitaka Yanase, Glenn M. Eastwood, Ian Baldwin, and Rinaldo Bellomo. "Extracorporeal Ammonia Clearance for Hyperammonemia in Critically Ill Patients: A Scoping Review." Blood Purification, December 4, 2020, 1–9. http://dx.doi.org/10.1159/000512100.

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<b><i>Introduction:</i></b> Hyperammonemia is a life-threatening condition. However, clearance of ammonia via extracorporeal treatment has not been systematically evaluated. <b><i>Methods:</i></b> We searched EMBASE and MEDLINE databases. We included all publications reporting ammonia clearance by extracorporeal treatment in adult and pediatric patients with clearance estimated by direct dialysate ammonia measurement or calculated by formula. Two reviewers screened and extracted data independently. <b><i>Results:</i></b> W
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