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Eden, Aimee R. "Jan Riordan: An Oral History." Journal of Human Lactation 35, no. 2 (March 22, 2019): 215–18. http://dx.doi.org/10.1177/0890334419830993.
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While conducting my dissertation research on the professionalization of breastfeeding support, I identified key “founders” of lactation consulting. I focused on the people involved in the formation of the International Board Certified Lactation Consultant, as certified by the International Board of Lactation Consultant Examiners and represented by the International Lactation Consultant Association. Jan Riordan was at the top of my list. As the editor and co-author of the first text on breastfeeding and human lactation for non-physicians, Dr. Riordan shaped the professional body of knowledge for International Board Certified Lactation Consultants and others providing clinical breastfeeding support. She was a La Leche League leader and founding member of the Kansas La Leche League International Chapter, served on the first International Board of Lactation Consultant Examiners Board of Directors, and served on the first editorial review board of the Journal of Human Lactation. She was a professor of nursing at Wichita State University for 23 years. I met her at an International Lactation Consultant Association conference in San Antonio, Texas in 2010, just after she had retired from Wichita State, and I interviewed her by phone on August 10, 2010. This is from a taped interview. (AE = Aimee Eden’s initials; JR = Jan Riordan’s initials). The University of South Florida IRB approved the full study.
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Walker, Robert V., and Jorgen Rud. "History of the international association of oral surgeons 1962–1986 and international association of oral and maxillofacial surgeons 1986–1996. Part I." International Journal of Oral and Maxillofacial Surgery 25, no. 4 (August 1996): 254–63. http://dx.doi.org/10.1016/s0901-5027(06)80051-2.
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Ritchie, Donald A. "Giving a Voice to the Oppressed: The International Oral History Association, Between Political Movements and Academic Networks." Oral History Review 47, no. 2 (June 16, 2020): 363–64. http://dx.doi.org/10.1080/00940798.2020.1771930.
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Petticrew, Ellen L. "Thirty years of sediment - water science: history, trends and future directions." Marine and Freshwater Research 60, no. 7 (2009): 611. http://dx.doi.org/10.1071/mf08119.
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In 1976, an interdisciplinary group of international researchers met in Amsterdam to share their knowledge about sediment–water interactions, and subsequently formed the International Association for Sediment Water Science (IASWS). Since then, IASWS has met tri-annually at a variety of locations throughout the world. Over the last 30 years, over 1000 oral presentations have been presented at IASWS symposia, more than half of which have been published as books or special issues of scientific journals. As such, the publications provide an excellent record of developments in the field of sediment–water interactions over the last 30 years. This paper provides an overview of the history of the Association, and a qualitative and quantitative content analysis of the IASWS publications. Changing patterns of research in some of the dominant symposia themes, including sediment-associated nutrients, contaminants and metals as well as sediment dynamics and material cycling are presented. Temporal changes in the investigative scale of published studies and an eventual increase in papers addressing management considerations were observed. Potential directions for the future of IASWS and some directives for ensuring that future research informs aquatic ecosystem health are suggested.
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Peres, K. G., W. M. Thomson, B. W. Chaffee, M. A. Peres, N. Birungi, L. G. Do, C. A. Feldens, et al. "Oral Health Birth Cohort Studies: Achievements, Challenges, and Potential." Journal of Dental Research 99, no. 12 (July 17, 2020): 1321–31. http://dx.doi.org/10.1177/0022034520942208.
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Birth cohorts are those among observational studies that provide understanding of the natural history and causality of diseases since early in life. Discussions during an International Association for Dental Research symposium in London, United Kingdom, in 2018, followed by a workshop in Bangkok, Thailand, in 2019, concluded that there are few birth cohort studies that consider oral health and that a broader discussion on similarities and differences among those studies would be valuable. This article aims to 1) bring together available long-term data of oral health birth cohort studies from the low, middle, and high-income countries worldwide and 2) describe similarities and differences among these studies. This work comprises 15 studies from all 5 continents. The most studied dental conditions and exposures are identified; findings are summarized; and methodological differences and similarities among studies are presented. Methodological strengths and weaknesses are also highlighted. Findings are summarized in 1) the negative impact of detrimental socioeconomic status on oral health changes over time, 2) the role of unfavorable patterns of dental visiting on oral health, 3) associations between general and oral health, 4) nutritional and dietary effects on oral health, and 5) intergenerational influences on oral health. Dental caries and dental visiting patterns have been recorded in all studies. Sources of fluoride exposure have been documented in most of the more recent studies. Despite some methodological differences in the way that the exposures and outcomes were measured, some findings are consistent. Predictive models have been used with caries risk tools, periodontitis occurrence, and permanent dentition orthodontic treatment need. The next steps of the group’s work are as follows: 1) establishing a consortium of oral health birth cohort studies, 2) conducting a scoping review, 3) exploring opportunities for pooled data analyses to answer pressing research questions, and 4) promoting and enabling the development of the next generation of oral health researchers.
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PANIOTTO, VOLODYMYR. "Our friend Melvin Kohn." Sociology: Theory, Methods, Marketing, Stmm. 2021 (2) (July 12, 2021): 197. http://dx.doi.org/10.15407/sociology2021.02.197.
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In the genre of oral history of sociology, the author narrates his experience of communication with the famous American sociologist, former president of the American Sociological Association (1987), honorary doctor of the Kiev-Mohyla Academy Melvin Lester Kohn (1928–2021). It is about the friendship and cooperation of Melvin Cohn with Ukrainian colleagues, his participation in the organization and holding of international research with the participation of Ukraine. The creative heritage of the American sociologist is important for the development of sociology in the world and in Ukraine, in particular for better understanding the social structure of Ukrainian society.
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Reis Pompeu de Moraes, Felipe. "Entrevista de Marieta de Moraes." Mosaico 13, no. 20 (July 18, 2021): 631–39. http://dx.doi.org/10.12660/rm.v13n20.2021.83084.
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Marieta de Moraes possui doutorado em História pela UFF (1991), pós-doutorado pela École des Hautes en Sciences Sociales (1997) e pós-doutorado pela USP (2011). Coordenadora Nacional do Mestrado Profissional em Ensino de História (2013-2017); Professora Emérita do Instituto de História da UFRJ; Coordenadora do Programa de História Oral do CPDOC (1992-1995); Editora da Revista Brasileira de História (2009-2013); Presidente da Associação brasileira de História Oral (1992-1994); Presidente da International Oral History Association(IOHA) e diretora do CPDOC (1999-2005); Pesquisadora e professora titular do CPDOC/FGV (1978/2012) e editora da Revista Estudos Históricos (1992/1998). Atualmente é coordenadora do programa FGV Ensino Médio; Diretora executiva da Editora FGV; Coordenadora do Projeto binacional e interdisciplinar "Capital cities: from nation to globalization" (2015/2016”) que contou com a participação de pesquisadores brasileiros e franceses (operação bilateral FAPERJ/Sorbonne). Tem experiência na área de História, com ênfase em História do Brasil República, atuando principalmente nas seguintes áreas: historiografia, história oral, históriapolítica, história do Rio de Janeiro.
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Woo, Ho Geol, Yoonkyung Chang, Ji Sung Lee, and Tae-Jin Song. "Tooth loss is associated with an increased risk of hypertension: A nationwide population-based cohort study." PLOS ONE 16, no. 6 (June 15, 2021): e0253257. http://dx.doi.org/10.1371/journal.pone.0253257.
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Tooth loss is closely associated with suboptimal oral care. Suboptimal oral care can facilitate local infections. These can lead to systemic inflammation and endothelial dysfunction, which are important pathological mechanisms of hypertension. The aim of this study was to investigate the link between tooth loss and the risk of hypertension. From the national health insurance system-health screening cohort in Korea, 19,680 participants who underwent three or more health examinations, including blood pressure measurements, between January 2003 and December 2008, without any history or diagnosis of hypertension were included in this study. Hypertension was defined as the diagnosis of hypertension (International Classification of Diseases-10 code “I10–11”) accompanied by the prescription of an antihypertensive agent or at least one health examination result of blood pressure of ≥140/90 mmHg. Kaplan-Meier survival curves with the log-rank test were used to evaluate the relationship between oral hygiene indicators and the incidence of hypertension. Cox proportional hazard models were applied to determine the association between oral hygiene indicators and the development of hypertension. During a median follow-up of 7.4 years, 1,853 patients developed hypertension. The estimated incidence of hypertension within seven years was 8.8%. Multivariable analysis confirmed a significant relationship between the number of lost teeth and hypertension (hazard ratio: 2.26; 95% confidence interval [1.24–4.10], p = 0.007, p for trend = 0.005). There was a positive association between the number of lost teeth and the risk of hypertension in a longitudinal research. In conclusion, the number of lost teeth may be associated with the risk of development of hypertension.
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Murray, Jeffrey C., Sandra Daack-Hirsch, Kenneth H. Buetow, Ronald Munger, Lourdes Espina, Nena Paglinawan, Edith Villanueva, John Rary, Kathy Magee, and William Magee. "Clinical and Epidemiologic Studies of Cleft up and Palate in the Philippines." Cleft Palate-Craniofacial Journal 34, no. 1 (January 1997): 7–10. http://dx.doi.org/10.1597/1545-1569_1997_034_0007_caesoc_2.3.co_2.
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Clinical and epidemiologic studies of defined geographic populations can serve as a means of establishing data important for genetic counseling and as a first step in Identifying strategies best suited for Identification of causes. Under the sponsorship of Operation Smile International, clinical, genetic, and epidemiologic studies were carried out at six sites within the Philippines between 1989 and 1996. Patients who were being evaluated for surgical repair of craniofacial anomalies (primarily clefts of the lip and palate) were briefly examined for the presence of associated anomalies, and a family history was obtained to look for the frequency of cleft lip and palate in siblings. Birth records of 47,969 newborns born over an 8-year period at one hospital in Bacolod City in the province of Negros Occidental were reviewed. Medical records of infants born with clefts of the lip and/or palate and other major anomalies were reviewed and birth prevalence rates calculated. Findings include a birth prevalence of 1.94 per 1000 live births for cleft lip with/without palate in the Philippines. Recurrence rates in siblings for nonsyndromic clefts of the lip and palate were 23 per 1000 for cleft lip with or without cleft palate, and 14 per 1000 for cleft palate only. The percentage of clefts associated with multiple anomalies was 21% at birth and 6% for individuals examined during the screening process, providing evidence for a high postnatal death rate. These data provide groundwork for additional etiologic studies including segregation analysis and molecular genetic studies involving linkage or association, as well as for studies of environmental contributions to clefting such as vitamin deficiencies. Preliminary molecular analysis using an association approach is reported in a companion paper. The findings suggest a high incidence of cleft lip and palate in native-born Filipinos.
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Hytrek-Hryciuk, Joanna. "Den Unterdrückten eine Stimme geben. Die International Oral History Association zwischen politischer Bewegung und wissenschaftlichem Netzwerk, Hgg. von Annette Leo und Franka Maubach, Göttingen 2013, ss. 378." Wrocławski Rocznik Historii Mówionej 3 (October 30, 2013): 273–76. http://dx.doi.org/10.26774/wrhm.58.
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Worthington, Leah, Rachel Donaldson, and Kieran Taylor. "Making Labor Visible in Historic Charleston." Labor 17, no. 1 (March 1, 2020): 45–73. http://dx.doi.org/10.1215/15476715-7962792.
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Charleston, South Carolina, is a city that markets itself as a center of heritage tourism. With millions of tourists visiting each year to see its historic architecture and landscaped gardens, how can public historians and public history professionals in Charleston and the Lowcountry accurately share the stories of workers, both enslaved and free, who built and fundamentally shaped the regional cultural landscape? The authors of this collaborative essay explore different avenues for ensuring that labor history and heritage—past and present—becomes integrated in the public history of the city and region. Through her work in historical interpretation at the McLeod Plantation Historic Site and the Lowcountry Digital History Initiative, Leah Worthington explores ways of publicly interpreting how enslaved people shaped the natural and structural landscapes of the Lowcountry—landscapes that are at the heart of the historical tourism industry. Rachel Donaldson examines the significance of the places of labor history and the importance of recognizing and preserving these sites as integral features of the region’s built environment. With the assistance of oral histories conducted with Leonard Riley Jr., a longshoreman and member of the International Longshoremen’s Association, her focus on the historical and contemporary significance of International Longshoremen’s halls in downtown Charleston sheds light on how sites like these have facilitated, and can continue to facilitate, labor and social activism. As Kieran Taylor argues, Charleston has a rich history of protest that fuses traditional labor demands for better wages and working conditions with demands for racial equality and black power. His project examines the efforts of African American workers in recent years to harness those traditions to build worker power at fast food restaurants, in hospitals, and in public services throughout the region.
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Noctor, Eoin, Catherine Crowe, Louise A. Carmody, Jean A. Saunders, Breda Kirwan, Angela O’Dea, Paddy Gillespie, et al. "Abnormal glucose tolerance post-gestational diabetes mellitus as defined by the International Association of Diabetes and Pregnancy Study Groups criteria." European Journal of Endocrinology 175, no. 4 (October 2016): 287–97. http://dx.doi.org/10.1530/eje-15-1260.
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Objective An increase in gestational diabetes mellitus (GDM) prevalence has been demonstrated across many countries with adoption of the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) diagnostic criteria. Here, we determine the cumulative incidence of abnormal glucose tolerance among women with previous GDM, and identify clinical risk factors predicting this. Design Two hundred and seventy women with previous IADPSG-defined GDM were prospectively followed up for 5years (mean 2.6) post-index pregnancy, and compared with 388 women with normal glucose tolerance (NGT) in pregnancy. Methods Cumulative incidence of abnormal glucose tolerance (using American Diabetes Association criteria for impaired fasting glucose, impaired glucose tolerance and diabetes) was determined using the Kaplan–Meier method of survival analysis. Cox regression models were constructed to test for factors predicting abnormal glucose tolerance. Results Twenty-six percent of women with previous GDM had abnormal glucose tolerance vs 4% with NGT, with the log-rank test demonstrating significantly different survival curves (P<0.001). Women meeting IADPSG, but not the World Health Organization (WHO) 1999 criteria, had a lower cumulative incidence than women meeting both sets of criteria, both in the early post-partum period (4.2% vs 21.7%, P<0.001) and at longer-term follow-up (13.7% vs 32.6%, P<0.001). Predictive factors were glucose levels on the pregnancy oral glucose tolerance test, family history of diabetes, gestational week at testing, and BMI at follow-up. Conclusions The proportion of women developing abnormal glucose tolerance remains high among those with IADPSG-defined GDM. This demonstrates the need for continued close follow-up, although the optimal frequency and method needs further study.
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Nouhjah, Sedigheh, Hajieh Shahbazian, Nahid Shahbazian, Alireza Jahanshahi, Shayesteh Jahanfar, and Bahman Cheraghian. "Incidence and Contributing Factors of Persistent Hyperglycemia at 6–12 Weeks Postpartum in Iranian Women with Gestational Diabetes: Results from LAGA Cohort Study." Journal of Diabetes Research 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/9786436.
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Background. A history of gestational diabetes is an important predictor of many metabolic disturbances later in life.Method. Life after gestational diabetes Ahvaz Study (LAGAs) is an ongoing population-based cohort study. Up to February 2016, 176 women with gestational diabetes underwent a 75 g oral glucose tolerance test (OGTT) at 6–12 weeks postpartum in Ahvaz (southwestern of Iran). Gestational diabetes was diagnosed according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and the American Diabetes Association (ADA) criteria applied for diagnosis of postpartum prediabetes and diabetes. Univariate and multivariate regression analysis were done.Results. Overall incidence of early postpartum glucose intolerance was 22.2% (95% CI, 16.3–29.0), 17.6% prediabetes (95% CI, 12.3–24.1) and 4.5% diabetes (95% CI, 2.0–8.8%). Independent risk factors for glucose intolerance were FPG ≥ 100 at the time of OGTT (OR 3.86; 95% CI; 1.60–9.32), earlier diagnosis of GDM (OR 0.92; 95% CI; 0.88–0.97), systolic blood pressure (OR 1.02; 95% CI; 1.002–1.04), and insulin or metformin therapy (OR 3.14; 95% CI; 1.20–8.21).Conclusion. Results determined a relatively high rate of glucose intolerance at 6–12 weeks after GDM pregnancy. Early postpartum screening of type 2 diabetes is needed particularly in women at high risk of type 2 diabetes.
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Jenum, Anne K., Kjersti Mørkrid, Line Sletner, Siri Vange, Johan L. Torper, Britt Nakstad, Nanna Voldner, et al. "Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a population-based cohort study." European Journal of Endocrinology 166, no. 2 (February 2012): 317–24. http://dx.doi.org/10.1530/eje-11-0866.
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ObjectiveThe International Association of Diabetes and Pregnancy Study Groups (IADPSG) recently proposed new criteria for diagnosing gestational diabetes mellitus (GDM). We compared prevalence rates, risk factors, and the effect of ethnicity using the World Health Organization (WHO) and modified IADPSG criteria.MethodsThis was a population-based cohort study of 823 (74% of eligible) healthy pregnant women, of whom 59% were from ethnic minorities. Universal screening was performed at 28±2 weeks of gestation with the 75 g oral glucose tolerance test (OGTT). Venous plasma glucose (PG) was measured on site. GDM was diagnosed as per the definition of WHO criteria as fasting PG (FPG) ≥7.0 or 2-h PG ≥7.8 mmol/l; and as per the modified IADPSG criteria as FPG ≥5.1 or 2-h PG ≥8.5 mmol/l.ResultsOGTT was performed in 759 women. Crude GDM prevalence was 13.0% with WHO (Western Europeans 11%, ethnic minorities 15%,P=0.14) and 31.5% with modified IADPSG criteria (Western Europeans 24%, ethnic minorities 37%,P< 0.001). Using the WHO criteria, ethnic minority origin was an independent predictor (South Asians, odds ratio (OR) 2.24 (95% confidence interval (CI) 1.26–3.97); Middle Easterners, OR 2.13 (1.12–4.08)) after adjustments for age, parity, and prepregnant body mass index (BMI). This increased OR was unapparent after further adjustments for body height (proxy for early life socioeconomic status), education and family history of diabetes. Using the modified IADPSG criteria, prepregnant BMI (1.09 (1.05–1.13)) and ethnic minority origin (South Asians, 2.54 (1.56–4.13)) were independent predictors, while education, body height and family history had little impact.ConclusionGDM prevalence was overall 2.4-times higher with the modified IADPSG criteria compared with the WHO criteria. The new criteria identified many subjects with a relatively mild increase in FPG, strongly associated with South Asian origin and prepregnant overweight.
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Franzago, Marica, Federica Fraticelli, Marta Di Nicola, Francesco Bianco, Daniela Marchetti, Claudio Celentano, Marco Liberati, Raffaele De Caterina, Liborio Stuppia, and Ester Vitacolonna. "Early Subclinical Atherosclerosis in Gestational Diabetes: The Predictive Role of Routine Biomarkers and Nutrigenetic Variants." Journal of Diabetes Research 2018 (December 24, 2018): 1–9. http://dx.doi.org/10.1155/2018/9242579.
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Gestational diabetes mellitus (GDM) can be considered a silent risk for out-of-pregnancy diabetes mellitus (DM) and cardiovascular disease (CVD) later in life. We aimed to assess the predictive role of 3rd trimester lipid profile during pregnancy for the susceptibility to markers of subclinical atherosclerosis (CVD susceptibility) at 3 years in a cohort of women with history of GDM. A secondary aim is to evaluate the usefulness of novel nutrigenetic markers, in addition to traditional parameters, for predicting early subclinical atherosclerosis in such women in order to plan adequate early prevention interventions. We assessed 28 consecutive GDM women in whom we collected socio-demographic characteristics and clinical and anthropometric parameters at the 3rd trimester of pregnancy. In a single blood sample, from each patient, we assessed 9 single nucleotide polymorphisms (SNPs) from 9 genes related to nutrients and metabolism, which were genotyped by High Resolution Melting analysis. All women then attended a 3-year-postpartum follow-up and on that occasion performed an oral glucose tolerance test (OGTT, with 75 g oral glucose), the measurement of carotid artery intima-media thickness (cIMT), and analyses of metabolic parameters. In addition, we evaluated the physical activity level and the adherence to Mediterranean diet (MedDiet) using the International Physical Activity Questionnaire (IPAQ-short version) and PREDIMED questionnaires. We found an association between 3rd trimester triglycerides and cIMT (p=0.014). We also found significant associations between the APOA5 CC genotype and cIMT after adjustments for age and body mass index (p=0.045) and between the interaction CC APOA5/CC LDLR and cIMT (p=0.010). At the follow-up, the cohort also featured a mean BMI in the overweight range and a high mean waist circumference. We found no difference in the MedDiet adherence, physical activity, and smoking but an inverse correlation between the PREDIMED and the IPAQ scores with the IMT. In conclusion, this preliminary study provides insight into the predictive role of lipid profile during pregnancy and of some genetic variants on cIMT taken as a parameter of subclinical CVD susceptibility in GDM.
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Lim, Wendy, Myra Wang, Karen Woods, Mark Crowther, and James Douketis. "The Management of Anticoagulated Patients Requiring Dental Extraction: A Cross-Sectional Survey of Oral Surgeons and Hematologists." Blood 108, no. 11 (November 16, 2006): 629. http://dx.doi.org/10.1182/blood.v108.11.629.629.
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Abstract Background: Studies in the dental literature and guidelines from the American Dental Association (ADA) and American College of Chest Physicians (ACCP) suggest that oral anticoagulants do not need to be discontinued prior to dental extraction. Despite this, anticoagulants are routinely discontinued due to perceived risks in bleeding. This practice may place patients at avoidable risk of thromboembolic complications. Objectives: To compare how oral surgeons and hematologists manage patients receiving long-term vitamin K antagonists (warfarin) who also require dental extraction. Design: Cross-sectional survey. Methods: Pre-tested surveys were mailed to 168 oral and maxillofacial surgeons and 123 hematologists/thromboembolism specialists licensed to practice in Ontario, Canada. The survey consisted of 3 parts: an assessment of bleeding and thrombotic risk factors that influence practioners’ decision to discontinue anticoagulants, individual scenarios assessing practice patterns, and clinical scenarios with varying risks of bleeding and thrombosis. For the clinical scenarios, respondents were asked to rate their risk perception on a 10-point scale, and the means and standard deviations of the responses between oral surgeons and hematologists were compared using unpaired t-tests, SPSS Version 12.0. Results: A total of 291 surveys were mailed with a response rate of 47% (136 surveys). 82 (60%) of the respondents were oral surgeons (75% community-based, 25% academic) and 54 (40%) were hematologists (28% community-based, 72% academic). Warfarin is routinely discontinued at least 50% of the time by 37% of dental surgeons, compared to 71% of hematologists; 29% of hematologists reported always discontinuing warfarin. The 3 main factors that influence oral surgeons’ and hematologists’ decision to discontinue warfarin are complicated procedures, multiple extractions and patients with a prior history of bleeding; 20% of hematologists discontinue anticoagulants because of specific referral to manage anticoagulants around the time of extraction. The maximum international normalized ratio (INR) that hematologists consider acceptable for extraction is 2.0, with no hematologists recommending extraction above this level; 86% of oral surgeons would proceed with extraction with an INR up to 3.0. In the individual scenarios, oral surgeons are more likely to continue warfarin and use local measures (sutures, gelfoam) to control bleeding. Hematologists are more likely to discontinue warfarin, use bridging anticoagulant therapy and recommend antifibrinolytic agents. In the clinical scenarios assessing thrombotic risk, oral surgeons are more likely to perceive that the risk of thrombosis is higher than hematologists (p < 0.01). In contrast, in the clinical scenarios assessing bleeding risk, the risk of bleeding was rated to be similar by both groups. Conclusions: Despite ADA and ACCP recommendations to continue anticoagulant therapy in most patients undergoing dental procedures, over 70% of hematologists, and 37% of dental surgeons in our survey frequently discontinue anticoagulants. Although the cited reasons for discontinuation are similar between the 2 groups, the frequency of discontinuation is significantly lower in oral surgeons and may be related to the perception that thromboembolic risks are high compared to hematologists’ risk assessments.
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Pintaudi, Basilio, Giacoma Di Vieste, Francesco Corrado, Giuseppe Lucisano, Fabio Pellegrini, Loretta Giunta, Antonio Nicolucci, Rosario D'Anna, and Antonino Di Benedetto. "Improvement of selective screening strategy for gestational diabetes through a more accurate definition of high-risk groups." European Journal of Endocrinology 170, no. 1 (January 2014): 87–93. http://dx.doi.org/10.1530/eje-13-0759.
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ObjectiveThis study aimed to assess the predictive value of risk factors (RFs) for gestational diabetes mellitus (GDM) established by selective screening (SS) and to identify subgroups of women at a higher risk of developing GDM.DesignA retrospective, single-center study design was employed.MethodsData of 1015 women screened for GDM at 24–28 weeks of gestation and diagnosed according to the International Association of Diabetes and Pregnancy Study Groups criteria were evaluated. Information on RFs established by SS was also collected and their association with GDM was determined. To identify distinct and homogeneous subgroups of patients at a higher risk, the RECursive Partitioning and AMalgamation (RECPAM) method was used.ResultsOverall, 113 (11.1%) women were diagnosed as having GDM. The application of the SS criteria would result in the execution of an oral glucose tolerance test (OGTT) in 58.3% of women and 26 (23.0%) cases of GDM would not be detected due to the absence of any RF. The RECPAM analysis identified high-risk subgroups characterized by fasting plasma glucose values >5.1 mmol/l (odds ratio (OR)=26.5; 95% CI 14.3–49.0) and pre-pregnancy BMI (OR=7.0; 95% CI 3.9–12.8 for overweight women). In a final logistic model including RECPAM classes, previous macrosomia (OR=3.6; 95% CI 1.1–11.6), and family history of diabetes (OR=1.8; 95% CI 1.1–2.8), but not maternal age, were also found to be associated with an increased risk of developing GDM. A screening approach based on the RECPAM model would reduce by over 50% (23.0 vs 10.6%) the number of undiagnosed GDM cases when compared with the current SS approach, at the expense of 50 additional OGTTs required.ConclusionsA screening approach based on our RECPAM model results in a significant reduction in the number of undetected GDM cases compared with the current SS procedure.
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Salehi, Maryam, Amie Hwang, Julia Simon, Thomas M. Mack, Tim Waterboer, and Wendy Cozen. "Past Infection and Risk of Adolescent/Young Adult Hodgkin Lymphoma." Blood 136, Supplement 1 (November 5, 2020): 26. http://dx.doi.org/10.1182/blood-2020-143270.
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Background: Adolescent/young adult (AYA) Hodgkin lymphoma (HL) is one of the most common cancers in this age group in developed countries. High socioeconomic status, small sibship size and lack of crowding in childhood are risk factors. We also found that among twins, the twin who had more oral exposures in early life was 80% less likely to develop AYA Hodgkin lymphoma. These risk factors are compatible with the hygiene hypothesis. We wanted to further explore additional risk factors consistent with this etiologic model. Methods: In a case-family control study, we examined past exposure to 12 infections in serum samples from 291 AYA HL cases and 194 of their unaffected family members. Cases were ascertained from the USC International Twin Registry (n=36) and the USC Cancer Surveillance Program (n=255). We measured antibodies to HSV1, HSV2, VZV, EBV, HHV7, HCMV, HHV6, KSHV, T. gondii, H. pylori, Rubella virus and Parvovirus B19 using a multiplex serology bead array (Luminex) (Waterboer Laboratory, German Cancer Research Center). A positive history of exposure to each infection was determined by a titer threshold specific for each infection. We did not examine the association between antibody levels and risk because of the possible impact of AYA HL diagnosis or treatment. We made the assumption that disease or treatment would not affect detection of a low level of antibody indicating previous exposure. A logistic regression model was used to calculate the odds ratio (OR) and 95% Confidence Interval (95% CI) adjusting for age at blood draw, sex and family. The sample was mostly non-Hispanic white, thus we did not adjust for race/ethnicity. We performed stratified analysis for histologic subtype where possible. Linear regression was used to calculate the p-for trend for 0, 1 or 2 fecal-oral or respiratory infections, with 0 infections as the reference. Results: The mean age at diagnosis in AYA HL cases was 30 years and the mean age at blood draw was 36 years. 57% of the cases were female. Out of the 186 cases with EBV tumor status, 78% were EBV-. Out of the 242 cases with histologic subtype, 72.5% were nodular sclerosis. The mean age of the 194 family controls at blood draw was 53 years and 63.4% were female. Evidence of past HHV6 infection was associated with an increased risk of AYA HL (OR= 1.80; 95% CI= 1.06-3.07; for nodular sclerosis only: OR= 1.92, 95% CI=1.05-3.42). Having antibodies to H. pylori was associated with a decreased risk (OR= 0.49; 95% CI= 0.25-0.98; for nodular sclerosis only: OR= 0.33, 95% CI= 0.14-0.77). An increasing number of fecal-oral infections (H. pylori, T. gondii) was associated with a decreasing risk of AYA HL (ptrend=0.015), while an increasing number of respiratory transmitted infections (Rubella virus, Parvovirus) was not significantly associated (ptrend=0.43). After adjusting for family, infection with Parvovirus was strongly and significantly associated with AYA HL (OR=3.8,1.06-13.6; for nodular sclerosis only: OR=10.5, 95% CI=1.71-65.25). Past infection with EBV was not associated with risk of overall HL, or with EBV- or EBV+ AYA HL separately, probably because of the high frequency of this infection in the overall population. Conclusions: We found continuing evidence for an inverse association between fecal-oral transmitted agents and risk of AYA HL, supporting the hypothesis that a deficit of early life fecal-oral transmitted microbes may be associated with susceptibility. HHV6 and Parvovirus were associated with an increased risk, possibly due to a subclinical immune deficiency or another unknown mechanism Disclosures No relevant conflicts of interest to declare.
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Vilanova, Mercedes. "International Oral History." History Workshop Journal 39, no. 1 (1995): 67–70. http://dx.doi.org/10.1093/hwj/39.1.67.
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Cho, H. J., M. S. Shin, Y. Song, S. K. Park, S. M. Park, and H. D. Kim. "Severe Periodontal Disease Increases Acute Myocardial Infarction and Stroke: A 10-Year Retrospective Follow-up Study." Journal of Dental Research 100, no. 7 (January 21, 2021): 706–13. http://dx.doi.org/10.1177/0022034520986097.
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This study aimed to evaluate the causal association of periodontal disease with acute myocardial infarction (AMI) and stroke, after controlling for various confounders among the Korean population. A retrospective cohort study using the National Health Insurance Service–National Health Screening Cohort (NHIS-HEALS) was performed during 2002 to 2015 (baseline: 2002 to 2005; follow-up: 2006 to 2015) in the Republic of Korea. A total of 298,128 participants with no history of AMI or stroke were followed up for 10 y. AMI and stroke were defined by a diagnosis using the International Classification of Diseases, 10th Revision ( ICD-10) guideline. Periodontal condition was classified into 3 groups (healthy, moderate periodontal disease, severe periodontal disease [SPD]) using the combination of ICD codes, treatment codes in the NHIS, and recommendation of periodontal treatment by the dentists in HEALS. Various confounders, such as sociodemographic, behavioral, systemic, and oral health factors, including hypercholesterolemia, were considered. Multivariable Cox regression analysis was applied to estimate adjusted incidence rate ratio (adjusted hazard ratio [aHR]) based on person-year of periodontal condition for AMI, stroke, and nonfatal major adverse cardiovascular events (MACEs) encompassing AMI or stroke controlling for various confounders. Stratified analyses according to age group, sex, and toothbrushing frequency were also performed. After controlling for various confounders, participants with SPD compared with non-SPD participants had a higher incidence by 11% for AMI (aHR, 1.11; 95% confidence interval [CI], 1.02–1.20), by 3.5% for stroke (aHR, 1.035; 95% CI, 1.01–1.07), and by 4.1% for MACEs (aHR, 1.04; 95% CI, 1.01–1.07). The association of SPD with AMI and MACE was highly modified in females and adults aged 40 to 59 y. In the total Korean population, SPD increased total AMI events by 4.3%, total stroke events by 1.4%, and the total MACEs by 1.6%. Our data confirmed that SPD was causally associated with the new events of AMI and stroke.
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Inaku, Kenneth Ogar, Boniface Uji Ago, Asuquo Bassey Ene, Eyam Sunday Eyam, Lawson Ekpeni Ekpe, Yeonun Mba Ogarekpe, Oluwakorede Ayodele Babatope, and Thomas Udagbor Agan. "Oral glucose tolerance outcomes among pregnant women receiving antenatal care in Calabar and environs – A pilot study." Calabar Journal of Health Sciences 4 (February 12, 2021): 71–78. http://dx.doi.org/10.25259/cjhs_45_2020.
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Objectives: Dysglycemia is a common metabolic alteration during pregnancy with adverse effects on both mother and fetus. This is related to the fact that pregnancy is associated with insulin resistance which is a harbinger for hyperglycemia. This study was carried out to find out the prevalence of gestational diabetes mellitus (GDM) among pregnant women in Calabar area using International Association of Diabetes and Pregnancy Study Group (IADPSG) diagnostic values. Material and Methods: This was a prospective, observational, cross-sectional study among pregnant women attending antenatal care in four health facilities in Calabar and adjoining areas conducted from September 2018 to August 2019. All consenting pregnant women were given 75 g glucose in 250–300 mL of water after 8–10 h overnight fast, without regard to the presence or absence of GDM risk factors. GDM diagnosis was made if any of the following glucose values were met or exceeded: (1) Fasting >92 mg/dl, (2) 1 h post-glucose load >180 mg/ dl, and (3) 2 h post-glucose load >153 mg/dl. Data were analyzed using IBM Statistical Package for the Social Sciences version 20.0 and results were presented using tables and a Venn diagram. Results: There were 345 pregnant women aged 18–50 (28.7 ± 6.3) years at 24–41 (29.6 ± 4.1) completed weeks of gestation. GDM was diagnosed in 48 (13.9%) women. Fasting plasma glucose cutoff diagnosed 81% while 37.5% and 50.0% met the diagnostic cutoff for 1 h and 2 h, respectively, and 15 (31.3%) women were positive for all three diagnostic cutoffs. Diabetes mellitus in a first-degree relative was the most common risk factor identified while hypertension in a first-degree relative and history of GDM was the least. Some 36.5% of women had no identifiable risk factors. Those who had positive fasting plasma glucose only (6.1%) were more than twice those diagnosed by 1 and 2 h only (2.6%) combined. The number of women with glucose values in the diabetic range was 6 (1.72%) but was classified as GDM since they were not previously known diabetics. Conclusion: This study has shown that the prevalence of GDM is 13.9% among women in Calabar and environs using the IADPSG criteria. Fasting plasma glucose can identify more than twice GDM patients than 1 and 2 h values combined. GDM still remains a major health issue among pregnant women hence there should be a national policy on routine screening for GDM with more studies being encouraged to determine the preferred glucose cutoff among Nigerians.
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Kang, Hye-Rim, Hyun Jin Song, Jin Hyun Nam, Sung-Hyun Hong, So-Young Yang, SangEun Ju, Sang Won Lee, Tae-Bum Kim, Hye-Lin Kim, and Eui-Kyung Lee. "Risk factors of asthma exacerbation based on asthma severity: a nationwide population-based observational study in South Korea." BMJ Open 8, no. 3 (March 2018): e020825. http://dx.doi.org/10.1136/bmjopen-2017-020825.
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ObjectivesAsthma exacerbation, associated with many risks factors, can reflect management failure. However, little is known about how risk factors are associated with exacerbation, according to asthma severity. We aimed to investigate differences in risk factors in patients with different asthma severity and evaluate whether risk factors differed between frequent exacerbators and patients with single exacerbation.DesignNationwide population-based observational study.SettingKorean National Sample Cohort database.ParticipantsWe included 22 130 adults with asthma diagnoses more than twice (ICD-10 (International Classification of Diseases, Tenth revision) codes J45 and J46) and one prescription for asthma medication from 2010 to 2011.Outcome measuresAsthma exacerbation was defined as having a corticosteroid (CS) burst characterised by a prescription of high-dose oral CS for ≥3 days or one systemic CS injection, hospitalisation or emergency department visit.ResultsAmong severities, history of CS bursts was significantly associated with exacerbation. In mild and moderate asthma, exacerbation was significantly associated with age ≥45 years, being female, gastro-oesophageal reflux disease and chronic rhinitis. High medication possession ratio (MPR≥50%), compared with low MPR (<20%) showed adjusted ORs of 0.828 (95% CI 0.707 to 0.971) and 0.362 (0.185 to 0.708) in moderate and severe asthma, respectively. In severe asthma, compared with mild asthma, only allergic rhinitis and history of hospitalisation were strongly associated with exacerbation. When comparing frequent exacerbators to patients with single exacerbation, age ≥45 years, atopic dermatitis, anxiety and history of CS burst were significant risk factors in mild and moderate asthma, whereas no risk factors were significant in severe asthma.ConclusionsDifferent associations between risk factors and asthma exacerbations based on asthma severity suggest that patients with mild asthma require greater attention to their age and comorbidities, whereas those with severe asthma require greater attention to hospitalisation history and drug adherence.
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Yarom, Noam, Charles L. Shapiro, Douglas E. Peterson, Catherine H. Van Poznak, Kari Bohlke, Salvatore L. Ruggiero, Cesar A. Migliorati, et al. "Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline." Journal of Clinical Oncology 37, no. 25 (September 1, 2019): 2270–90. http://dx.doi.org/10.1200/jco.19.01186.
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PURPOSE To provide guidance regarding best practices in the prevention and management of medication-related osteonecrosis of the jaw (MRONJ) in patients with cancer. METHODS Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and ASCO convened a multidisciplinary Expert Panel to evaluate the evidence and formulate recommendations. Guideline development involved a systematic review of the literature and a formal consensus process. PubMed and EMBASE were searched for studies of the prevention and management of MRONJ related to bone-modifying agents (BMAs) for oncologic indications published between January 2009 and December 2017. Results from an earlier systematic review (2003 to 2008) were also included. RESULTS The systematic review identified 132 publications, only 10 of which were randomized controlled trials. Recommendations underwent two rounds of consensus voting. RECOMMENDATIONS Currently, MRONJ is defined by (1) current or previous treatment with a BMA or angiogenic inhibitor, (2) exposed bone or bone that can be probed through an intraoral or extraoral fistula in the maxillofacial region and that has persisted for longer than 8 weeks, and (3) no history of radiation therapy to the jaws or metastatic disease to the jaws. In patients who initiate a BMA, preventive care includes comprehensive dental assessments, discussion of modifiable risk factors, and avoidance of elective dentoalveolar surgery (ie, surgery that involves the teeth or contiguous alveolar bone) during BMA treatment. It remains uncertain whether BMAs should be discontinued before dentoalveolar surgery. Staging of MRONJ should be performed by a clinician with experience in the management of MRONJ. Conservative measures comprise the initial approach to MRONJ treatment. Ongoing collaboration among the dentist, dental specialist, and oncologist is essential to optimal patient care.
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Haldar, Sumanto, Long Hui Wong, Alvin Suriya Tjahyo, Farhana Osman, Shia Lyn Tay, Priya Govindharajulu, Susanna Poh Suan Lim, et al. "Plant Based Foods to Improve Metabolic Health in Prediabetics – Protocol for a Randomized Controlled Trial." Current Developments in Nutrition 5, Supplement_2 (June 2021): 1278. http://dx.doi.org/10.1093/cdn/nzab057_008.
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Abstract Objectives The study will investigate the effectiveness of an Asian food based intervention to improve metabolic health, notably glucose homeostasis in a prediabetic population. Methods A parallel design randomized controlled trial will be conducted in Chinese prediabetics aged 45–75 years, BMI 19.5–32 kg/m2. Prediabetes defined according to the American Diabetes Association guideline: fasting blood glucose 5.6–6.9 mmol/l or hemoglobin A1c 5.7–6.4% or 2-hr oral glucose tolerance test 7.8–11.0 mmol/l. Major exclusion criteria were: smoking, food allergies or intolerances to common food ingredients, dietary restrictions, sustained hypertension (>160/95 mmHg), history of metabolic, cardiac, liver or kidney disorders, thyroid dysfunction and recent weight loss. The dietary intervention will last for 16 weeks, where volunteers will consume 2 specially formulated main meals per day, provided as pre-cooked, frozen, ready-meals (approximately 400 kcal each). The treatment group (TG) meals will be prepared with legumes, low GI rice or noodles, blended vegetable oil and added mixed herbs and spices. The control group (CG) meals, isocaloric, will consist of a portion of chicken, a portion of vegetables, medium to high GI rice or noodles and negligible herbs and spices. The male volunteers will be provided additional 100 kcal snacks containing either wholegrain cereals and nuts/seeds (TG) or refined cereal snack products (CG). The daily meals and snacks for rest of the day will be chosen freely, while a dietitian limits the total average calorie consumption to ensure around 5% weight loss in both groups. The effects of dietary interventions on metabolic health will be assessed at every 4 week intervals. The primary outcome measures will include several markers of glucose homeostasis (including HbA1c, fasting glucose, fasting insulin and a 2-hr oral glucose tolerance test [OGTT]). The secondary outcomes will include lipid profile, fructosamine, adiponectin, markers of oxidative stress and chronic inflammation. Results The recruitment for the study has been completed (n = 256 screened, n = 123 suitable). The dietary intervention will commence in March 2021 and expected to be completed in July 2021. Conclusions N/A. Funding Sources Jointly funded by the National University of Singapore, Agency of Science Technology and Research, Singapore, and Wilmar International Limited.
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Binnie, W. H., and J. H. P. Main. "International Association of Oral Pathologists VIIIth Congress." Journal of Oral Pathology and Medicine 25, no. 10 (November 1996): 565–66. http://dx.doi.org/10.1111/j.1600-0714.1996.tb01733.x.
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Rámišová, Šárka. "Zahraniční Výjezdy Československých Volejbalistů – Reflexe Zahraničí Očima Československých Sportovců v 50. a 60. Letech 20. Století." Acta Musei Nationalis Pragae – Historia 71, no. 1-2 (2017): 32–43. http://dx.doi.org/10.2478/amnh-2017-0005.
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The present paper focuses on the resumption of individual sports associations foreign relations after 1945, and how it was affected both by the resumption of international sport matches and by exit permits of Czechoslovak athletes. Travelling abroad used to be highly regulated in this period and not many citizens met the strict conditions applied. Athletes thus received a status of state representants, became to an extent, privileged and had to, therefore, meet certain requirements. They also gained access to information and insight unavailable to ordinary citizens. The study analyses the differences between the trips to the so-called “friendly”, i.e. communist, countries and to the West, from the amounts of money spent on representations abroad to the reception by the host countries. The study focuses mainly on volleyball representatives whose golden age spanned the 1950s and 1960s and who were therefore considered the sport elite promoting volleyball in the world, in this period. Athletes would commonly share their experiences from abroad and pass these on to their fellow citizens during organised discussions or personal meetings. After finishing their active career, some sports representatives were approached by foreign organisations and offered further engagement. Even such matters were, however, regulated by The Czechoslovak Union of Physical Education and Sport. The life experiences and paths of selected athletes, through documents, diaries and oral history interviews, map out their reflection on foreign countries and on the issue of otherness.
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Bakel, M. A., H. Esen-Baur, Leen Boer, Bronislaw Malinowski, A. P. Borsboom, Betty Meehan, H. J. M. Claessen, et al. "Book Reviews." Bijdragen tot de taal-, land- en volkenkunde / Journal of the Humanities and Social Sciences of Southeast Asia 141, no. 1 (1985): 149–88. http://dx.doi.org/10.1163/22134379-90003405.
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- M.A. van Bakel, H. Esen-Baur, Untersuchungen über den vogelmann-kult auf der Osterinsel, 1983, Franz Steiner Verlag GmbH, 399 pp. - Leen Boer, Bronislaw Malinowski, Malinowski in Mexico. The economics of a Mexican market system, edited and with an introduction by Susan Drucker-Brown, London: Routledge and Kegan Paul, 1982 (International Library of Anthropology)., Julio de la Fuente (eds.) - A.P. Borsboom, Betty Meehan, Shell bed to shell midden, Australian Institute of Aboriginal Studies, Canberra, 1982. - H.J.M. Claessen, Peter Geschiere, Village communities and the state. Changing relations among the Maka of Southeastern Cameroon since the colonial conquest. Monographs of the African Studies Centre, Leiden. London: Routledge and Kegan Paul Ltd. 1982. 512 pp. Appendices, index, bibliography, etc. - H.J.M. Claessen, Jukka Siikala, Cult and conflict in tropical Polynesia; A study of traditional religion, Christianity and Nativistic movements, Helsinki: Academia Scientiarum Fennica, 1982, 308 pp. Maps, figs., bibliography. - H.J.M. Claessen, Alain Testart, Les Chasseurs-Cueilleurs ou l’Origine des Inégalités, Mémoires de la Sociéte d’Ethnographie 26, Paris 1982. 254 pp., maps, bibliography and figures. - Walter Dostal, Frederik Barth, Sohar - Culture and society in an Omani town. Baltimore - London: The Johns Hopkins University Press, 1983, 264 pp., ill. - Benno Galjart, G.J. Kruyer, Bevrijdingswetenschap. Een partijdige visie op de Derde Wereld [Emancipatory Science. A partisan view of the Third World], Meppel: Boom, 1983. - Sjaak van der Geest, Christine Okali, Cocoa and kinship in Ghana: The matrilineal Akan of Ghana. London: Kegan Paul International (in association with the International African Institute), 1983. 179 pp., tables, index. - Serge Genest, Claude Tardits, Contribution de la recherche ethnologique à l’histoire des civilisations du Cameroun / The contribution of enthnological research to the history of Cameroun cultures. Paris, CNRS, 1981, two tomes, 597 pp. - Silvia W. de Groot, Sally Price, Co-wives and calabashes, Ann Arbor, The University of Michigan Press, 1984, 224 p., ill. - N.O. Kielstra, Gene R. Garthwaite, Khans and Shahs. A documentary analysis of the Bakhtiary in Iran, Cambridge University Press, Cambridge, 1983. 213 pp. - G.L. Koster, Jeff Opland, Xhosa oral poetry. Aspects of a black South African tradition, Cambridge Studies in oral and literate culture 7, Cambridge University Press, Cambridge , London, New York, New Rochelle, Melbourne, Sydney, 1983, XII + 303 pp. - Adam Kuper, Hans Medick, Interest and emotion: Essays on the study of family and kinship, Cambridge University Press, 1984., David Warren Sabean (eds.) - C.A. van Peursen, Peter Kloos, Antropologie als wetenschap. Coutinho, Muidenberg 1984 (204 p.). - Jerome Rousseau, Jeannine Koubi, Rambu solo’: “la fumée descend”. Le culte des morts chez les Toradja du Sud. Paris: Editions du CNRS, 1982. 530 pages, 3 maps, 73 pictures. - H.C.G. Schoenaker, Miklós Szalay, Ethnologie und Geschichte: zur Grundlegung einer ethnologischen geschichtsschreibung; mit beispielen aus der Geschichte der Khoi-San in Südafrika. Dietrich Reimer Verlag, Berlin 1983, 292 S. - F.J.M. Selier, Ghaus Ansari, Town-talk, the dynamics of urban anthropology, 170 pp., Leiden: E.J. Brill, 1983., Peter J.M. Nas (eds.) - A.A. Trouwborst, Serge Tcherkézoff, Le Roi Nyamwezi, la droite et la gauche. Revision comparative des classifications dualistes. Cambridge: Cambridge University Press, Paris:Éditions de la Maison des sciences de l’homme, 1983, 154 pp. - Pieter van der Velde, H. Boekraad, Te Elfder Ure 32: Verwantschap en produktiewijze, Jaargang 26 nummer 3 (maart 1983)., G. van den Brink, R. Raatgever (eds.) - E.Ch.L. van der Vliet, Sally Humphreys, The family, women and death. Comparative studies. London, Boston etc.: Routledge & Kegan Paul, 1983 (International Library of Anthropology). xiv + 210 pp. - W.F. Wertheim, T. Svensson, Indonesia and Malaysia. Scandinavian Studies in Contemporary Society. Scandinavian Institute of Asian Studies: Studies on Asian Topics no. 5. London and Malmö: Curzon Press, 1983, 282 pp., P. Sørensen (eds.) - H.O. Willems, Detlef Franke, Altägyptische verwandtschaftsbezeichnungen im Mittleren Reich, Hamburg, Verlag Born GmbH, 1983.
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Simpson, Jacqueline. "The Local Legend: A Product of Popular Culture." Rural History 2, no. 1 (April 1991): 25–35. http://dx.doi.org/10.1017/s0956793300002600.
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In the study of folktales, both in Britain and internationally, the privileged genre has always been the fairytale, the märchen or ‘Wonder Tale’. These complex, picturesque stories, such as ‘Snow White’ or ‘Cinderella’, have attracted innumerable scholarly collectors and interpreters. There is, however, another kind of oral folk narrative, equally widespread but less glamorous, which has far more to offer to the student of popular rural culture. I refer to the kind of story technically known to English-speaking folklorists as a ‘legend’ (German Sage). This centres upon some specific place, person or object which really exists or has existed within the knowledge of those telling and hearing the story. It reflects the beliefs, moral judgements and everyday preoccupations of the social group, and is in many cases, though not invariably, told ‘as true’. Its aim is to hand on accounts of significant events alleged to have occurred in a particular community or area and it has no truck with ‘once.upon a time’ and the ‘never-never land’. While the fairytale is long and is told for its entertainment value, the legend is almost always brief, for its normal context is casual conversation, where it is recounted in order to inform, explain, warn or educate. Its style is sober and realistic, for though it may contain supernatural and fantastic elements, these are given maximum plausibility by being brought into close association with the physical localisation of the tale.
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Ornstein, Moshe, Sudipto Mukherjee, Michael K. Keng, Paul Elson, Ramon V. Tiu, Yogenthiran Saunthararajah, Leslie Farhat, et al. "Vancomycin-Resistant Enterococcus (VRE) Bacteremia During Acute Myeloid Leukemia (AML) Induction Therapy Is an Independent Predictor of Poor Outcome." Blood 120, no. 21 (November 16, 2012): 1487. http://dx.doi.org/10.1182/blood.v120.21.1487.1487.
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Abstract Abstract 1487 The presence of VRE bacteremia in hematopoietic stem cell transplant recipients portends a worsening clinical course and poor overall survival (Avery et al; BMT, 2005). The impact of VRE bacteremia on outcome in AML patients (pts) receiving induction chemotherapy (IC) has not been established. We conducted an IRB-approved retrospective study of AML pts who received cytarabine-based IC at Cleveland Clinic between 2000–2008 to determine VRE rates and effect on complete remission (CR) and overall survival (OS). Data on age at AML diagnosis (dx), gender, diabetes, smoking history, history of antecedent hematological disorder, pathologic classification, hematologic parameters at dx and at VRE occurrence, metaphase cytogenetics (per CALGB/Alliance 8461), precedingnon-VRE bacteremias, invasive fungal infection (IFI), time from dx and induction to VRE and number of VRE infections, complete remission (CR) and overall survival (OS) were collected from our AML database. The association of these factors with VRE bacteremia was assessed using Fisher's exact test, the Cochran-Armitage trend test and Wilcoxon rank sum test. The impact of VRE bacteremia on OS was assessed using a 2:1 matched-pairs analysis based on gender and year of dx (+ 3 years), and factors known to influence outcome: age at dx (+ 5 years), etiology, and cytogenetic risk. The timing of VRE was also accounted for in the matching. Frailty models, which included a term for WBC at dx, were use to assess the impact of VRE bacteremia while taking into account both the impact of WBC and the paired nature of the data. Of 350 pts evaluable for analysis, the median age at dx was 57 years (range 19–88); 192 (55%) were male; 114 (33%) had secondary AML; median baseline WBC was 10.4K/mL (range, 0.48–550); cytogenetic risk distribution was favorable (14%), intermediate (54%), and unfavorable (32%); 45% were current or former smokers; 17% had a history of diabetes; and 7% had IFI. With the exception of IFI (16% in pts with VRE versus 6% in non-VRE pts, p=.04) there were no significant differences in these factors between the two groups (all p>.08). Of 37 pts (9.8%) who had documented VRE bacteremias during IC, the median interval from the start of IC to VRE infection was 17 days (range, 9–58). The majority (89%) of VRE bacteremias occurred in pts receiving IC between 2005 and 2008 (infection rate of 22%, 33/152) while only 4 infections occurred in 198 pts treated between 2000 and 2004 (infection rate of 2%). One plausible explanation for this epidemiologic shift could be the frequent use of fluoroquinolone prohylaxis to prevent neutropenic fever, which became routine in 2004. The overall CR rate for the cohort was 73%; 70% in VRE pts and 73% in non-VRE pts (p=0.7). Median follow-up was 72.2 months (range 1.1–145.4). Unadjusted median OS for the entire cohort was 12.8 months (95% C.I. 10.6–15.9); 7.1 months (95% C.I. 3.9–16.5) for VRE pts and 13.1 months (95% C.I. 11.2–16.3) for non-VRE pts (p=0.13, Figure 1A). Using the 2:1 matching to adjust for the impact of age, etiology, and cytogenetics, VRE pts had a significantly inferior OS compared to non-VRE pts even after adjusting for WBC at dx (p=0.04 and.80, respectively, Figure 1B). Mutivariableanalyses confirmed this association. In conclusion, VRE bacteremia in pts undergoing IC for AML is an independent risk factor for worse OS. The routine use of fluoroquinoloneprophylaxis is likely contributing to the increased prevalence of VRE bacteremia. Consideration should therefore be given to escalating VRE appropriate antibiotic care in these patients sooner and in the post-remission setting. Figure 1. Survival from Diagnosis A. All patients B. VRE cases and matched controls Figure 1. Survival from Diagnosis . / A. All patients . / B. VRE cases and matched controls Disclosures: Saunthararajah: Cleveland Clinic Innovation: patent application for oral THU-decitabine., patent application for oral THU-decitabine. Patents & Royalties. Advani:Genzyme: Honoraria, Research Funding; Immunomedics: Research Funding. Maciejewski:NIH: Research Funding; Aplastic Anemia&MDS International Foundation: Research Funding.
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Cronin, Mike, Mark Duncan, and Paul Rouse. "The Gaelic Athletic Association Oral History Project." International Journal of the History of Sport 36, no. 13-14 (September 22, 2019): 1311–26. http://dx.doi.org/10.1080/09523367.2019.1698548.
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Ritchie, D. A. "The Oral History Association After Twenty Years." Oral History Review 15, no. 1 (March 1, 1987): v—vi. http://dx.doi.org/10.1093/ohr/15.1.v.
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Givens, Douglas R. "Oral History Index: An International Directory of Oral History Interviews, Meckler Corporation, 1990." Bulletin of the History of Archaeology 2, no. 2 (November 2, 1992): 14. http://dx.doi.org/10.5334/bha.02205.
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Patel, Ameet, Hants Williams, Maria R. Baer, Ann Butler Zimrin, and Jennie Y. Law. "Use of Direct Oral Anticoagulants in Patients with Sickle Cell Disease and Venous Thromboembolism Is Associated with a Significant Decrease in Incidence of Bleeding Compared to Vitamin K Antagonists and Low-Molecular-Weight Heparins." Blood 130, Suppl_1 (December 7, 2017): 978. http://dx.doi.org/10.1182/blood.v130.suppl_1.978.978.
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Abstract Background: Venous thromboembolism (VTE) is a recognized complication of sickle cell disease (SCD). Several studies confirm that SCD itself is an independent risk factor for development of VTE. However, the optimal pharmacologic anticoagulant remains unknown. Methods: This retrospective single-institution cohort study was exempt by the Institutional Review Board. Data were collected via review of electronic medical records including ambulatory, emergency department, general floor, and intensive care unit encounters. Patients with SCD were identified spanning 1/2009-7/2017 using ICD 9/10 codes. Inclusion criteria were age ≥18 years at time of VTE diagnosis, imaging confirming VTE, and documented compliance based on INR values and/or provider/pharmacy documentation. VTE diagnosis included deep vein thrombosis (DVT) at any location and pulmonary embolism based on documented imaging and ICD 9/10 codes. Anticoagulants included direct oral anticoagulants (DOACs), vitamin K antagonists (VKA), and low-molecular-weight heparin (LMWH). The DOACs used in this study were rivaroxaban, apixaban and dabigatran. Exclusion criteria were known active malignancy, confirmed hypercoagulable risk factors beyond SCD, atrial fibrillation and/or history of major bleeding prior to anticoagulation. Due to low event rates, a log likelihood ratio test of independence was calculated for associations between drug type and two endpoints: bleeding rate and rate of VTE recurrence. Rate of VTE recurrence was defined as a newly diagnosed VTE within 6 months of initiation of anticoagulation. Bleeding rate was defined using International Society on Thrombosis and Hemostasis criteria: bleeding event into a critical site and/or a ≥2 point decrease in baseline hemoglobin. Results: A total of 109 patients with SCD met inclusion criteria. 66 patients (60%) were female. SCD genotypes represented included HbSS in 91 patients (83%), HbSC in 12 (11%) and HbS β+ thalassemia in 4 (4%). There were no patients with HbS-β0 thalassemia. VTEs consisted of 69 DVTs and 43 pulmonary emboli. 31 out of 109 VTEs were provoked, including 30 catheter-related incidents. After initial VTE event, 32 patients received a VKA, 34 received LMWH, and 43 received a DOAC. Within the class of DOACs, 31 patients received rivaroxaban, 5 received apixaban, and 7 received dabigatran. Sixteen of 109 patients (15%) experienced a clinically significant bleeding event, including 8 on VKA, 6 on LMWH, and 2 on a DOAC. Bleeding incidence was least with the DOAC class [0.22 CI (0.04-0.84) p < 0.05], greatest with warfarin [1.55 CI (0.57-4.33) p < 0.05] and slightly less with LMWH [0.64 CI (0.23-1.73) p < 0.05]. There was a significant decrease in incidence of bleeding events in patients receiving a DOAC for anticoagulation, compared to a VKA or LMWH (p = 0.033). At a median follow-up of 11.8 months (range, 3.4 - 60 months), 33 patients had a recurrent VTE, including 10 on VKA, 10 on LMWH and 13 taking a DOAC (p = 0.833). An association between VTE and SCD genotype could not be identified due to small numbers of patients with non-HbSS genotypes. Conclusion: In patients with SCD and VTE, there was a significant decrease in incidence of bleeding events in patients receiving a DOAC for anticoagulation, compared to a VKA or LMWH (p = 0.033). There was no difference between VTE recurrence rate and choice of initial anticoagulation. Figure Figure. Disclosures No relevant conflicts of interest to declare.
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Mantha, Simon, Ann M. Pianka, and Nicholas P. Tsapatsaris. "Determinants of Intracranial Hemorrhage Incidence in Patients on Oral Anticoagulation Followed at the Lahey Clinic." Blood 116, no. 21 (November 19, 2010): 1101. http://dx.doi.org/10.1182/blood.v116.21.1101.1101.
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Abstract Abstract 1101 Background: oral anticoagulation with warfarin is used to treat venous and arterial thromboembolic disease. Its administration is associated with a risk of intracranial hemorrhage (ICH), a devastating complication which usually results in death or severe disability. The international normalized ratio (INR) is one of the factors which can help determine the risk of ICH in a given individual (Singer DE et al, Circ Cardiovasc Qual Outcomes 2009). Materials and methods: using the DoseResponse® patient database at our institution, we carried out a retrospective nested matched case-control study to identify patient characteristics associated with the occurrence of ICH. The database was queried for the years 2007 to 2009. Each case was matched by month to 4 control patients having a routine INR determination for the monitoring of chronic anticoagulation. The following characteristics were captured: INR, age, sex, systolic and diastolic blood pressure, hemoglobin, creatinine, history of pertinent medical conditions (hypertension, diabetes, heart failure, gastrointestinal bleeding, ischemic stroke, active cancer, substance abuse, cirrhosis), indication for anticoagulation (non-valvular atrial fibrillation, valvular atrial fibrillation, venous thromboembolism or other) and intake of antiplatelet agent. Blood pressure for cases was obtained from a medical encounter occurring before the bleeding event. The relationship between those risk factors and the odds ratio of ICH was determined with conditional logistic regression, using the SAS® 9.2 software platform. The initial approach consisted of stepwise regression with forward selection and backward elimination. Results: 31 cases of ICH were retrieved; they were matched to 124 controls. In the univariate analysis, the two groups differed significantly only in terms of their hemoglobin: 12.8 versus 13.5 g/dL for cases and controls, respectively (p=0.048). As for the INR, the mean value was 3.0 for cases vs 2.5 for controls. The distribution of this parameter was normal albeit more markedly skewed to the right for cases, with 3 values of 5.0 or more, compared to only one instance of this for controls. Most cases of ICH occurred in the setting of a therapeutic INR. The odds ratio (OR) of ICH (using the interval 2.01 to 2.50 as the reference) started increasing above an INR of 3.50, reaching its highest level in individuals with an INR value greater than 4.50 (OR=5.78, 95% CI=1.10-30.48). Mean blood pressures were similar between the two groups: 92 vs 89 mmHg for cases vs controls, respectively (p=0.252). The variables retained in the final regression model on the basis of statistical significance and clinical pertinence are shown in the table. The OR of ICH was 1.50 for increments of 1.0 in INR value (p=0.021), while it was 1.56 for increments of 10 mmHg in mean blood pressure (p=0.032). The presence of cancer, anemia and heart failure appeared to contribute to the risk of an event but the associations for those factors were not statistically significant. Conclusion: the INR is an important predictor for the incidence of ICH, but a supratherapeutic measurement is found only in a minority of cases; the risk of an event increases markedly with an INR above 3.5. Mean blood pressure is another important determinant of the risk of ICH in individuals on chronic warfarin therapy. Previous studies have shown that a diagnosis of hypertension is associated with an increased risk of ICH in the anticoagulated patient population (Berwaerts J et al, QJM 2000; Atrial Fibrillation Investigators, Arch Intern Med 1994; Singer DE et al, Ann Intern Med 2009), but to the knowledge of this author there has been no report describing the variation in this risk over the spectrum of mean blood pressures. This lends support to the generally accepted practice of aggressively treating arterial hypertension in patients on chronic oral anticoagulation. Multivariable Analysis Disclosures: No relevant conflicts of interest to declare.
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Orimo, Hajime. "History of International Association of Gerontology(IAG)." Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 35, no. 3 (1998): 178–85. http://dx.doi.org/10.3143/geriatrics.35.178.
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Fowkes, Robert A. "The International Linguistic Association: A subjective history." WORD 45, no. 1 (April 1, 1994): 1–17. http://dx.doi.org/10.1080/00437956.1994.12098335.
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Morgan, Karl Z. "History of the International Radiation Protection Association." Health Physics 74, no. 6 (June 1998): 644–45. http://dx.doi.org/10.1097/00004032-199806000-00002.
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Canali, Cinzia, Anthony N. Maluccio, Tiziano Vecchiato, and Marianne Berry. "The international association: Origins, history, and development." Children and Youth Services Review 31, no. 10 (October 2009): 1069–73. http://dx.doi.org/10.1016/j.childyouth.2009.07.022.
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Whitten, Charles. "History of the International Association of Geodesy." Bulletin Géodésique 62, no. 3 (September 1988): 197–206. http://dx.doi.org/10.1007/bf02520704.
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Louis, M. "History of the International Association of Geodesy." Bulletin G�od�sique 66, no. 2 (1992): 79–81. http://dx.doi.org/10.1007/bf00989249.
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Zivadinov, R., K. Willheim, D. Sepic-Grahovac, A. Jurjevic, M. Bucuk, O. Brnabic-Razmilic, G. Relja, and M. Zorzon. "Migraine and Tension-Type Headache in Croatia: A Population-Based Survey of Precipitating Factors." Cephalalgia 23, no. 5 (June 2003): 336–43. http://dx.doi.org/10.1046/j.1468-2982.2003.00544.x.
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The careful monitoring of the trigger factors of headache could be an important step in treatment, because their avoidance may lessen the frequency and severity of attacks. Furthermore, they may provide a clue to the aetiology of headache. The aim of the present study was to estimate the prevalence of tension-type headache (TTH) and to establish the frequency of precipitating factors in subjects with migraine and TTH in the adult population of Bakar, County of the Coast and Gorski Kotar, Croatia. Another important purpose of the study was to examine the relationship of the precipitating factors with migraine and TTH, and with migraine subtypes: migraine with aura (MA) and migraine without aura (MO). We performed a population-based survey using a ‘face-to-face door-to-door’ interview method. The surveyed population consisted of 5173 residents aged between 15 and 65 years. The 3794 participants (73.3%) were screened for headache history according to the International Headache Society (IHS) criteria. Headache screen-positive responders, 2475 (65.2%), were interviewed by trained medical students with a structured detailed interview focused on the precipitating factors. The following precipitating factors in lifetime migraineurs and tension-type headachers have been assessed: stress, sleep disturbances, eating habits, menstrual cycle, oral contraceptives, food items, afferent stimulation, changes in weather conditions and temperature, frequent travelling and physical activity. A total of 720 lifetime migraineurs and 1319 tension-type headachers have been identified. The most common precipitants for both migraine and TTH were stress and frequent travelling. Stress (odds ratio (OR) 1.4, 95% confidence interval (CI) 1.17, 1.69) was associated with migraine, whereas physical activity (OR 0.72, 95% CI 0.59, 0.87) was related to TTH. Considering MA and MO, frequent travelling (OR 2.2, 95% CI 1.59, 2.99), food items (OR 2.2, 95% CI 1.35, 3.51) and changes in weather conditions and temperature (OR 1.75, 95% CI 1.27, 2.41) exhibited a significant positive association with MA. The present study demonstrated that precipitant-dependent attacks are frequent among both migraineurs and tensiontype headachers. Lifetime migraineurs experienced headache attacks preceded by triggering factors more frequently than tension-type headachers. MA was more frequently associated with precipitating factors than MO. We suggest that some triggering factors may contribute to the higher occurrence of precipitant-dependent headache attacks in susceptible individuals.
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Woo, Ho-Geol, Yoon-Kyung Chang, Ji-Sung Lee, and Tae-Jin Song. "Association of Periodontal Disease with the Occurrence of Unruptured Cerebral Aneurysm among Adults in Korea: A Nationwide Population-Based Cohort Study TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //." Medicina 57, no. 9 (August 30, 2021): 910. http://dx.doi.org/10.3390/medicina57090910.
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Background and Objectives: Cerebral aneurysms can cause disability or death during rupture, but information on the etiology of cerebral aneurysms is currently lacking. Periodontal disease causes both systemic inflammation and local inflammation of the oral cavity. Systemic inflammation is a major cause of cerebral aneurysms. The aim of our study was to determine whether the presence of periodontal disease is related to the occurrence of unruptured cerebral aneurysms in a nationwide population-based cohort. Materials and Methods: We analyzed data on demographics, previous medical history, and laboratory test results of 209,620 participants from the Korean National Health Insurance System-Health Screening Cohort. The presence of periodontal disease and oral hygiene parameters, including the number of lost teeth, tooth brushing frequency per day, dental visits for any reason, and expert teeth scaling, were investigated. The occurrences of unruptured cerebral aneurysms (I67.1) were defined according to the International Statistical Classification of Diseases Related Health Problems-10. Results: The mean age of the participants was 53.7 ± 8.7 years, and 59.4% were male. Periodontal disease was found in 20.9% of the participants. A total of 2160 (1.0%) cases of unruptured cerebral aneurysms developed after 10.3 years of median follow up. In multivariate analysis, the presence of periodontal disease was significantly associated with an increased risk of unruptured cerebral aneurysms (hazard ratio: 1.21, 95% confidence interval: 1.09–1.34, p < 0.001). Conclusion: The presence of periodontal disease could be associated with the occurrence of unruptured cerebral aneurysms. It should be noted that when periodontal diseases are present, the risk of aneurysms is increased in the future.
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GELBIER, S. "History of the International Association of Paediatric Dentistry." International Journal of Paediatric Dentistry 4, no. 4 (April 24, 2009): 281–88. http://dx.doi.org/10.1111/j.1365-263x.1994.tb00148.x.
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GELBIER, S. "History of the International Association of Paediatric Dentistry." International Journal of Paediatric Dentistry 5, no. 3 (April 24, 2009): 199–204. http://dx.doi.org/10.1111/j.1365-263x.1995.tb00308.x.
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Hitchon, Brian. "International Association of Geochemistry and Cosmochemistry: a history." Applied Geochemistry 1, no. 1 (January 1986): 7–14. http://dx.doi.org/10.1016/0883-2927(86)90033-8.
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Thomson, Alistair. "Fifty Years On: An International Perspective on Oral History." Journal of American History 85, no. 2 (September 1998): 581. http://dx.doi.org/10.2307/2567753.
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Main, J. H. P. "Proceedings of the Biennial Congress of the International Association of Oral Pathologists." Journal of Oral Pathology & Medicine 16, no. 4 (July 13, 2007): 181. http://dx.doi.org/10.1111/j.1600-0714.1987.tb02062.x.
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Zinsser, Judith P. "The World History Association: Teaching as an International Movement." History Teacher 31, no. 2 (February 1998): 259. http://dx.doi.org/10.2307/494071.
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Hewett, R. S. "The History of the International Association of Agricultural Economists." History of Political Economy 25, no. 3 (September 1, 1993): 551–52. http://dx.doi.org/10.1215/00182702-25-3-551.
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Friedman, Aaron, Jochen Ehrich, Robert Chevalier, and Sally Jones. "A history of the International Pediatric Nephrology Association (IPNA)." Pediatric Nephrology 27, no. 5 (March 6, 2012): 695. http://dx.doi.org/10.1007/s00467-012-2134-8.
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