Academic literature on the topic 'Interpolated Markov model'

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Journal articles on the topic "Interpolated Markov model"

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Jones, P. G., and P. K. Thornton. "Fitting a third-order Markov rainfall model to interpolated climate surfaces." Agricultural and Forest Meteorology 97, no. 3 (November 1999): 213–31. http://dx.doi.org/10.1016/s0168-1923(99)00067-2.

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Aguilar, F. J., M. A. Aguilar, J. L. Blanco, A. Nemmaoui, and A. M. García Lorca. "ANALYSIS AND VALIDATION OF GRID DEM GENERATION BASED ON GAUSSIAN MARKOV RANDOM FIELD." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B2 (June 7, 2016): 277–84. http://dx.doi.org/10.5194/isprs-archives-xli-b2-277-2016.

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Digital Elevation Models (DEMs) are considered as one of the most relevant geospatial data to carry out land-cover and land-use classification. This work deals with the application of a mathematical framework based on a Gaussian Markov Random Field (GMRF) to interpolate grid DEMs from scattered elevation data. The performance of the GMRF interpolation model was tested on a set of LiDAR data (0.87 points/m<sup>2</sup>) provided by the Spanish Government (PNOA Programme) over a complex working area mainly covered by greenhouses in Almería, Spain. The original LiDAR data was decimated by randomly removing different fractions of the original points (from 10% to up to 99% of points removed). In every case, the remaining points (scattered observed points) were used to obtain a 1 m grid spacing GMRF-interpolated Digital Surface Model (DSM) whose accuracy was assessed by means of the set of previously extracted checkpoints. The GMRF accuracy results were compared with those provided by the widely known Triangulation with Linear Interpolation (TLI). Finally, the GMRF method was applied to a real-world case consisting of filling the LiDAR-derived DSM gaps after manually filtering out non-ground points to obtain a Digital Terrain Model (DTM). Regarding accuracy, both GMRF and TLI produced visually pleasing and similar results in terms of vertical accuracy. As an added bonus, the GMRF mathematical framework makes possible to both retrieve the estimated uncertainty for every interpolated elevation point (the DEM uncertainty) and include break lines or terrain discontinuities between adjacent cells to produce higher quality DTMs.
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Aguilar, F. J., M. A. Aguilar, J. L. Blanco, A. Nemmaoui, and A. M. García Lorca. "ANALYSIS AND VALIDATION OF GRID DEM GENERATION BASED ON GAUSSIAN MARKOV RANDOM FIELD." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B2 (June 7, 2016): 277–84. http://dx.doi.org/10.5194/isprsarchives-xli-b2-277-2016.

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Digital Elevation Models (DEMs) are considered as one of the most relevant geospatial data to carry out land-cover and land-use classification. This work deals with the application of a mathematical framework based on a Gaussian Markov Random Field (GMRF) to interpolate grid DEMs from scattered elevation data. The performance of the GMRF interpolation model was tested on a set of LiDAR data (0.87 points/m&lt;sup&gt;2&lt;/sup&gt;) provided by the Spanish Government (PNOA Programme) over a complex working area mainly covered by greenhouses in Almería, Spain. The original LiDAR data was decimated by randomly removing different fractions of the original points (from 10% to up to 99% of points removed). In every case, the remaining points (scattered observed points) were used to obtain a 1 m grid spacing GMRF-interpolated Digital Surface Model (DSM) whose accuracy was assessed by means of the set of previously extracted checkpoints. The GMRF accuracy results were compared with those provided by the widely known Triangulation with Linear Interpolation (TLI). Finally, the GMRF method was applied to a real-world case consisting of filling the LiDAR-derived DSM gaps after manually filtering out non-ground points to obtain a Digital Terrain Model (DTM). Regarding accuracy, both GMRF and TLI produced visually pleasing and similar results in terms of vertical accuracy. As an added bonus, the GMRF mathematical framework makes possible to both retrieve the estimated uncertainty for every interpolated elevation point (the DEM uncertainty) and include break lines or terrain discontinuities between adjacent cells to produce higher quality DTMs.
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Burks, David J., and Rajeev K. Azad. "Higher-order Markov models for metagenomic sequence classification." Bioinformatics 36, no. 14 (June 9, 2020): 4130–36. http://dx.doi.org/10.1093/bioinformatics/btaa562.

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Abstract Motivation Alignment-free, stochastic models derived from k-mer distributions representing reference genome sequences have a rich history in the classification of DNA sequences. In particular, the variants of Markov models have previously been used extensively. Higher-order Markov models have been used with caution, perhaps sparingly, primarily because of the lack of enough training data and computational power. Advances in sequencing technology and computation have enabled exploitation of the predictive power of higher-order models. We, therefore, revisited higher-order Markov models and assessed their performance in classifying metagenomic sequences. Results Comparative assessment of higher-order models (HOMs, 9th order or higher) with interpolated Markov model, interpolated context model and lower-order models (8th order or lower) was performed on metagenomic datasets constructed using sequenced prokaryotic genomes. Our results show that HOMs outperform other models in classifying metagenomic fragments as short as 100 nt at all taxonomic ranks, and at lower ranks when the fragment size was increased to 250 nt. HOMs were also found to be significantly more accurate than local alignment which is widely relied upon for taxonomic classification of metagenomic sequences. A novel software implementation written in C++ performs classification faster than the existing Markovian metagenomic classifiers and can therefore be used as a standalone classifier or in conjunction with existing taxonomic classifiers for more robust classification of metagenomic sequences. Availability and implementation The software has been made available at https://github.com/djburks/SMM. Contact Rajeev.Azad@unt.edu Supplementary information Supplementary data are available at Bioinformatics online.
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Cunial, Fabio, Jarno Alanko, and Djamal Belazzougui. "A framework for space-efficient variable-order Markov models." Bioinformatics 35, no. 22 (April 20, 2019): 4607–16. http://dx.doi.org/10.1093/bioinformatics/btz268.

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Abstract Motivation Markov models with contexts of variable length are widely used in bioinformatics for representing sets of sequences with similar biological properties. When models contain many long contexts, existing implementations are either unable to handle genome-scale training datasets within typical memory budgets, or they are optimized for specific model variants and are thus inflexible. Results We provide practical, versatile representations of variable-order Markov models and of interpolated Markov models, that support a large number of context-selection criteria, scoring functions, probability smoothing methods, and interpolations, and that take up to four times less space than previous implementations based on the suffix array, regardless of the number and length of contexts, and up to ten times less space than previous trie-based representations, or more, while matching the size of related, state-of-the-art data structures from Natural Language Processing. We describe how to further compress our indexes to a quantity related to the redundancy of the training data, saving up to 90% of their space on very repetitive datasets, and making them become up to 60 times smaller than previous implementations based on the suffix array. Finally, we show how to exploit constraints on the length and frequency of contexts to further shrink our compressed indexes to half of their size or more, achieving data structures that are a hundred times smaller than previous implementations based on the suffix array, or more. This allows variable-order Markov models to be used with bigger datasets and with longer contexts on the same hardware, thus possibly enabling new applications. Availability and implementation https://github.com/jnalanko/VOMM Supplementary information Supplementary data are available at Bioinformatics online.
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Ardid, Alberto, David Dempsey, Edward Bertrand, Fabian Sepulveda, Pascal Tarits, Flora Solon, and Rosalind Archer. "Bayesian magnetotelluric inversion using methylene blue structural priors for imaging shallow conductors in geothermal fields." GEOPHYSICS 86, no. 3 (April 8, 2021): E171—E183. http://dx.doi.org/10.1190/geo2020-0226.1.

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In geothermal exploration, magnetotelluric (MT) data and inversion models are commonly used to image shallow conductors typically associated with the presence of an electrically conductive clay cap that overlies the main reservoir. However, these inversion models suffer from nonuniqueness and uncertainty, and the inclusion of useful geologic information is still limited. We have developed a Bayesian inversion method that integrates the electrical resistivity distribution from MT surveys with borehole methylene blue (MeB) data, an indicator of conductive clay content. The MeB data were used to inform structural priors for the MT Bayesian inversion that focus on inferring with uncertainty the shallow conductor boundary in geothermal fields. By incorporating borehole information, our inversion reduced nonuniqueness and then explicitly represented the irreducible uncertainty as estimated depth intervals for the conductor boundary. We used the Markov chain Monte Carlo and a 1D three-layer resistivity model to accelerate the Bayesian inversion of the MT signal beneath each station. Then, inferred conductor boundary distributions were interpolated to construct pseudo-2D/3D models of the uncertain conductor geometry. We compare our approach against deterministic MT inversion software on synthetic and field examples, and our approach has good performance in estimating the depth to the bottom of the conductor, a valuable target in geothermal reservoir exploration.
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Zhu, Yuxin, Yanchen Bo, Jinzong Zhang, and Yuexiang Wang. "Fusion of Multisensor SSTs Based on the Spatiotemporal Hierarchical Bayesian Model." Journal of Atmospheric and Oceanic Technology 35, no. 1 (January 2018): 91–109. http://dx.doi.org/10.1175/jtech-d-17-0116.1.

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AbstractThis study focuses on merging MODIS-mapped SSTs with 4-km spatial resolution and AMSR-E optimally interpolated SSTs at 25-km resolution. A new data fusion method was developed—the Spatiotemporal Hierarchical Bayesian Model (STHBM). This method, which is implemented through the Markov chain Monte Carlo technique utilized to extract inferential results, is specified hierarchically by decomposing the SST spatiotemporal process into three subprocesses, that is, the spatial trend process, the seasonal cycle process, and the spatiotemporal random effect process. Spatial-scale transformation and spatiotemporal variation are introduced into the fusion model through the data model and model parameters, respectively, with suitably selected link functions. Compared with two modern spatiotemporal statistical methods—the Bayesian maximum entropy and the robust fixed rank kriging—STHBM has the following strength: it can simultaneously meet the expression of uncertainties from data and model, seamless scale transformation, and SST spatiotemporal process simulation. Utilizing multisensors’ complementation, merged data with complete spatial coverage, high resolution (4 km), and fine spatial pattern lying in MODIS SSTs can be obtained through STHBM. The merged data are assessed for local spatial structure, overall accuracy, and local accuracy. The evaluation results illustrate that STHBM can provide spatially complete SST fields with reasonably good data values and acceptable errors, and that the merged SSTs collect fine spatial patterns lying in MODIS SSTs with fine resolution. The accuracy of merged SSTs is between MODIS and AMSR-E SSTs. The contribution to the accuracy and the spatial pattern of the merged SSTs from the original MODIS SSTs is stronger than that of the original AMSR-E SSTs.
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Liang, Chia-Chun, Wei-Chung Hsu, Yao-Te Tsai, Shao-Jen Weng, Ho-Pang Yang, and Shih-Chia Liu. "Healthy Life Expectancies by the Effects of Hypertension and Diabetes for the Middle Aged and Over in Taiwan." International Journal of Environmental Research and Public Health 17, no. 12 (June 18, 2020): 4390. http://dx.doi.org/10.3390/ijerph17124390.

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(1) Introduction: This study aims to investigate the disparity in the healthy life expectancy of the elderly with hypertension and diabetes mellitus. (2) Materials and Methods: This study used survey data collected in five waves (1996, 1999, 2003, 2007, and 2011) of the “Taiwan Longitudinal Study on Aging” (TLSA) to estimate the life expectancy and healthy life expectancy of different age groups. The activities of daily living, the health condition of hypertension and diabetes and the survival statuses of these cases were analyzed by the IMaCh (Interpolated Markov Chain) and logistic regression model. (3) Results: As regards the elderly between age 50 and 60 with hypertension and diabetes, women with hypertension only exhibited the longest life expectancy, and the healthy life expectancy and the percentage of remaining life with no functional incapacity were 33.74 years and 87.11%, respectively. In contrast, men with diabetes only showed the shortest life expectancy, and the healthy life expectancy and the percentage of remaining life with no functional incapacity were 22.51 years and 93.16%, respectively. We also found that people with diabetes showed a lower percentage of remaining life with no functional incapacity. (4) Conclusions: We suggest that policymakers should pay special attention to publicizing the importance of health control behavior in order to decrease the risk of suffering diseases and to improve the elderly’s quality of life.
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Reubelt, T., G. Austen, and E. W. Grafarend. "Space Gravity Spectroscopy - determination of the Earth’s gravitational field by means of Newton interpolated LEO ephemeris Case studies on dynamic (CHAMP Rapid Science Orbit) and kinematic orbits." Advances in Geosciences 1 (July 11, 2003): 127–35. http://dx.doi.org/10.5194/adgeo-1-127-2003.

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Abstract. An algorithm for the (kinematic) orbit analysis of a Low Earth Orbiting (LEO) GPS tracked satellite to determine the spherical harmonic coefficients of the terrestrial gravitational field is presented. A contribution to existing long wavelength gravity field models is expected since the kinematic orbit of a LEO satellite can nowadays be determined with very high accuracy in the range of a few centimeters. To demonstrate the applicability of the proposed method, first results from the analysis of real CHAMP Rapid Science (dynamic) Orbits (RSO) and kinematic orbits are illustrated. In particular, we take advantage of Newton’s Law of Motion which balances the acceleration vector and the gradient of the gravitational potential with respect to an Inertial Frame of Reference (IRF). The satellite’s acceleration vector is determined by means of the second order functional of Newton’s Interpolation Formula from relative satellite ephemeris (baselines) with respect to the IRF. Therefore the satellite ephemeris, which are normally given in a Body fixed Frame of Reference (BRF) have to be transformed into the IRF. Subsequently the Newton interpolated accelerations have to be reduced for disturbing gravitational and non-gravitational accelerations in order to obtain the accelerations caused by the Earth’s gravitational field. For a first insight in real data processing these reductions have been neglected. The gradient of the gravitational potential, conventionally expressed in vector-valued spherical harmonics and given in a Body Fixed Frame of Reference, must be transformed from BRF to IRF by means of the polar motion matrix, the precession-nutation matrices and the Greenwich Siderial Time Angle (GAST). The resulting linear system of equations is solved by means of a least squares adjustment in terms of a Gauss-Markov model in order to estimate the spherical harmonics coefficients of the Earth’s gravitational field.Key words. space gravity spectroscopy, spherical harmonics series expansion, GPS tracked LEO satellites, kinematic
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Salzberg, Steven L., Mihaela Pertea, Arthur L. Delcher, Malcolm J. Gardner, and Hervé Tettelin. "Interpolated Markov Models for Eukaryotic Gene Finding." Genomics 59, no. 1 (July 1999): 24–31. http://dx.doi.org/10.1006/geno.1999.5854.

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Dissertations / Theses on the topic "Interpolated Markov model"

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Abramowicz, Konrad. "Numerical analysis for random processes and fields and related design problems." Doctoral thesis, Umeå universitet, Institutionen för matematik och matematisk statistik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-46156.

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In this thesis, we study numerical analysis for random processes and fields. We investigate the behavior of the approximation accuracy for specific linear methods based on a finite number of observations. Furthermore, we propose techniques for optimizing performance of the methods for particular classes of random functions. The thesis consists of an introductory survey of the subject and related theory and four papers (A-D). In paper A, we study a Hermite spline approximation of quadratic mean continuous and differentiable random processes with an isolated point singularity. We consider a piecewise polynomial approximation combining two different Hermite interpolation splines for the interval adjacent to the singularity point and for the remaining part. For locally stationary random processes, sequences of sampling designs eliminating asymptotically the effect of the singularity are constructed. In Paper B, we focus on approximation of quadratic mean continuous real-valued random fields by a multivariate piecewise linear interpolator based on a finite number of observations placed on a hyperrectangular grid. We extend the concept of local stationarity to random fields and for the fields from this class, we provide an exact asymptotics for the approximation accuracy. Some asymptotic optimization results are also provided. In Paper C, we investigate numerical approximation of integrals (quadrature) of random functions over the unit hypercube. We study the asymptotics of a stratified Monte Carlo quadrature based on a finite number of randomly chosen observations in strata generated by a hyperrectangular grid. For the locally stationary random fields (introduced in Paper B), we derive exact asymptotic results together with some optimization methods. Moreover, for a certain class of random functions with an isolated singularity, we construct a sequence of designs eliminating the effect of the singularity. In Paper D, we consider a Monte Carlo pricing method for arithmetic Asian options. An estimator is constructed using a piecewise constant approximation of an underlying asset price process. For a wide class of Lévy market models, we provide upper bounds for the discretization error and the variance of the estimator. We construct an algorithm for accurate simulations with controlled discretization and Monte Carlo errors, andobtain the estimates of the option price with a predetermined accuracy at a given confidence level. Additionally, for the Black-Scholes model, we optimize the performance of the estimator by using a suitable variance reduction technique.
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Hafez, Dina Mohamed. "A Semi-Supervised Predictive Model to Link Regulatory Regions to Their Target Genes." Diss., 2015. http://hdl.handle.net/10161/11314.

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Next generation sequencing technologies have provided us with a wealth of data profiling a diverse range of biological processes. In an effort to better understand the process of gene regulation, two predictive machine learning models specifically tailored for analyzing gene transcription and polyadenylation are presented.

Transcriptional enhancers are specific DNA sequences that act as ``information integration hubs" to confer regulatory requirements on a given cell. These non-coding DNA sequences can regulate genes from long distances, or across chromosomes, and their relationships with their target genes are not limited to one-to-one. With thousands of putative enhancers and less than 14,000 protein-coding genes, detecting enhancer-gene pairs becomes a very complex machine learning and data analysis challenge.

In order to predict these specific-sequences and link them to genes they regulate, we developed McEnhancer. Using DNAseI sensitivity data and annotated in-situ hybridization gene expression clusters, McEnhancer builds interpolated Markov models to learn enriched sequence content of known enhancer-gene pairs and predicts unknown interactions in a semi-supervised learning algorithm. Classification of predicted relationships were 73-98% accurate for gene sets with varying levels of initial known examples. Predicted interactions showed a great overlap when compared to Hi-C identified interactions. Enrichment of known functionally related TF binding motifs, enhancer-associated histone modification marks, along with corresponding developmental time point was highly evident.

On the other hand, pre-mRNA cleavage and polyadenylation is an essential step for 3'-end maturation and subsequent stability and degradation of mRNAs. This process is highly controlled by cis-regulatory elements surrounding the cleavage site (polyA site), which are frequently constrained by sequence content and position. More than 50\% of human transcripts have multiple functional polyA sites, and the specific use of alternative polyA sites (APA) results in isoforms with variable 3'-UTRs, thus potentially affecting gene regulation. Elucidating the regulatory mechanisms underlying differential polyA preferences in multiple cell types has been hindered by the lack of appropriate tests for determining APAs with significant differences across multiple libraries.

We specified a linear effects regression model to identify tissue-specific biases indicating regulated APA; the significance of differences between tissue types was assessed by an appropriately designed permutation test. This combination allowed us to identify highly specific subsets of APA events in the individual tissue types. Predictive kernel-based SVM models successfully classified constitutive polyA sites from a biologically relevant background (auROC = 99.6%), as well as tissue-specific regulated sets from each other. The main cis-regulatory elements described for polyadenylation were found to be a strong, and highly informative, hallmark for constitutive sites only. Tissue-specific regulated sites were found to contain other regulatory motifs, with the canonical PAS signal being nearly absent at brain-specific sites. We applied this model on SRp20 data, an RNA binding protein that might be involved in oncogene activation and obtained interesting insights.

Together, these two models contribute to the understanding of enhancers and the key role they play in regulating tissue-specific expression patterns during development, as well as provide a better understanding of the diversity of post-transcriptional gene regulation in multiple tissue types.


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Book chapters on the topic "Interpolated Markov model"

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Zhu, Hongmei, Jiaxin Wang, Zehong Yang, and Yixu Song. "Interpolated Hidden Markov Models Estimated Using Conditional ML for Eukaryotic Gene Annotation." In Computational Intelligence and Bioinformatics, 267–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11816102_29.

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Anand, Adarsh, Shakshi Singhal, and Ompal Singh. "Revisiting Dynamic Potential Adopter Diffusion Models under the Influence of Irregular Fluctuations in Adoption Rate." In Handbook of Research on Promoting Business Process Improvement Through Inventory Control Techniques, 499–519. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-3232-3.ch026.

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A pragmatic innovation diffusion model is proposed in the present chapter that interpolates stochasticity in the logistic formulation of the widely-acknowledged Bass model with dynamic market size. These irregular changes are caused due to uncertainty attached to the socioeconomic and political environment in which an innovation is positioned that affects the action of potential adopters leading to their non-uniform behavior. The aim of the current study is to find the analytical solution for the two dynamic market expansion structures, namely, linear and exponential under the influence of irregular fluctuations whose closed-form solutions were not possible in the existing literature. In addition to the changeable market size, the proposed innovation diffusion also incorporates the concept of repeat purchase. The anticipated stochastic differential equation based new product diffusion model is then expounded methodically using the Itô process and Itô's integral equation. Further, the model has been used to study the growth pattern of different consumer durable products.
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Conference papers on the topic "Interpolated Markov model"

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Jafarzadeh, Saeed, and Jane Berk. "Enhancing wind power forecasting: A bootstrap resampling interpolated Markov model." In 2016 North American Power Symposium (NAPS). IEEE, 2016. http://dx.doi.org/10.1109/naps.2016.7747910.

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Chrysos, Grigorios, Euripides Sotiriades, Ioannis Papaefstathiou, and Apostolos Dollas. "A FPGA based coprocessor for gene finding using Interpolated Markov Model (IMM)." In 2009 International Conference on Field Programmable Logic and Applications (FPL). IEEE, 2009. http://dx.doi.org/10.1109/fpl.2009.5272367.

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