Academic literature on the topic 'Intervertebral disc'

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Journal articles on the topic "Intervertebral disc"

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Jiang, Feng. "Nucleus Pulposus Cell Senescence in IVDD: Mechanisms and Therapeutic Perspectives." International Journal of Biology and Life Sciences 10, no. 1 (2025): 61–67. https://doi.org/10.54097/2ggt8s93.

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Intervertebral disc degeneration (IVDD) is a common spinal pathological process that leads to the degeneration of the structure and function of the intervertebral disc, causing low back pain and nerve root compression. The molecular mechanism of intervertebral disc degeneration is not fully understood, but cellular senescence is an important factor. This article summarizes the characteristics, causes, signal transduction pathways and treatment methods of cellular senescence in intervertebral disc degeneration, including inhibiting the expression or activity of genes or signal pathways related
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Chavan, Dr Vishwajeet R., and Dr Sanjay Patil. "Radioneucleoplasty Therapy in Intervertebral Disc Herniation." Indian Journal of Applied Research 4, no. 4 (2011): 441–42. http://dx.doi.org/10.15373/2249555x/apr2014/136.

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Bodnarchuk, J. A., M. V. Khyzhnjak, О. О. Potapov, and N. G. Chopik. "BIOCHEMICAL AND BIOMECHANICAL SUBSTANTIATION OF REPARATIVE REGENERATION OF INTERVERTEBRAL DISCS IN PATIENTS WITH DEGENERATIVE DISC DISEASES." Eastern Ukrainian Medical Journal 8, no. 3 (2020): 249–54. http://dx.doi.org/10.21272/eumj.2020;8(3):249-254.

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Degenerative disc diseases occupy the second place in the overall structure of morbidity with temporary disability. In 40% of patients with spinal osteochondrosis, diseases of the locomotor apparatus and connective tissue cause primary disability. Disc degeneration is a pathological process that is the main cause of low back pain and is observed in the vast majority of people at some point in their lives. The influence of mechanical stress leads to degenerative changes in the tissues of the nucleus pulposus of the intervertebral disc. Limited transport and low cellular saturation of the discs
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ANDERSSON, GUNNAR B. J., HOWARD S. AN, THEODORE R. OEGEMA, and LORI A. SETTON. "INTERVERTEBRAL DISC DEGENERATION." Journal of Bone and Joint Surgery-American Volume 88, no. 4 (2006): 895–99. http://dx.doi.org/10.2106/00004623-200604000-00028.

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KATZ, MICHAEL M., ALAN R. HARGENS, and STEVEN R. GARFIN. "Intervertebral Disc Nutrition." Clinical Orthopaedics and Related Research &NA;, no. 210 (1986): 243???245. http://dx.doi.org/10.1097/00003086-198609000-00035.

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Cassidy, J. David, Dwight Loback, Ken Yong-Hing, and Stanley Tchang. "Intervertebral Disc Derniation." Spine 17, no. 5 (1992): 570–74. http://dx.doi.org/10.1097/00007632-199205000-00016.

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Fairbank, Jeremy. "Prolapsed intervertebral disc." BMJ 336, no. 7657 (2008): 1317–18. http://dx.doi.org/10.1136/bmj.39583.438773.80.

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Bhettay, E., D. Joubert, O. L. Meyers, and B. Cremin. "Intervertebral Disc Calcification." Clinical Pediatrics 31, no. 7 (1992): 446–47. http://dx.doi.org/10.1177/000992289203100714.

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Skalli, Wafa, and Jean Dubousset. "Intervertebral disc transplantation." Lancet 369, no. 9566 (2007): 968–69. http://dx.doi.org/10.1016/s0140-6736(07)60469-3.

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Wu, Jiann-Jiu, and David R. Eyre. "Intervertebral Disc Collagen." Journal of Biological Chemistry 278, no. 27 (2003): 24521–25. http://dx.doi.org/10.1074/jbc.m302431200.

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Dissertations / Theses on the topic "Intervertebral disc"

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Stefanakis, Manos. "Biomechanics of intervertebral disc pain." Thesis, University of Bristol, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556723.

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'Background: Back pain is strongly (but variably) associated with degeneration of intervertebral discs. Mechanical loading has long been considered one of the causes of disc pathology and pain, but its precise role is poorly understood. In particular the spatial relation between load distribution inside the disc, the disc matrix changes as a result of load and their relationship with pain has not been researched. Methods: Distribution of compressive stress inside intervertebral discs from all regions of the spine was studied using stress profilometry in cadaveric motion segments. Matrix pathol
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Lemos, Felipe Fernandes [UNESP]. "Influência da desidratação no comportamento mecânico do disco intervertebral lombar." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/105330.

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Made available in DSpace on 2014-06-11T19:34:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-07-22Bitstream added on 2014-06-13T21:06:51Z : No. of bitstreams: 1 lemos_ff_dr_guara_parcial.pdf: 67760 bytes, checksum: 8abbb6c32f12d888cf49226d69fd138e (MD5) Bitstreams deleted on 2014-10-03T16:24:39Z: lemos_ff_dr_guara_parcial.pdf,Bitstream added on 2014-10-03T16:27:37Z : No. of bitstreams: 2 lemos_ff_dr_guara_parcial.pdf.txt: 11034 bytes, checksum: 59c288b2b373bbe58255effddd89bb52 (MD5) 000671151.pdf: 2407167 bytes, checksum: 0e13b6a8dfac5d68060ec4460476f509 (MD5) Bitstreams deleted
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González, Guitiérrez Ramiro Arturo. "Biomechanical study of intervertebral disc degeneration." Doctoral thesis, Universitat Politècnica de Catalunya, 2012. http://hdl.handle.net/10803/76781.

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Degeneration and age affect the biomechanics of the intervertebral disc, by reducing its stiffness, flexibility and shock absorption capacities against daily movement and spinal load. The biomechanical characterization of intervertebral discs is achieved by conducting mechanical testing to vertebra-disc-vertebra segments and applying axial, shear, bend and torsion loads, statically or dynamically, with load magnitudes corresponding to the physiological range. However, traditional testing does not give a view of the load and deformation states of the disc components: nucleus pulposus, annulus f
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Osti, Orso L. "Annular tears and intervertebral disc degeneration /." Title page, contents and abstract only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09pho85.pdf.

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Liu, Jane J. "Proteoglycans of the human intervertebral disc." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=68204.

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The composition and heterogeneity of human intervertebral disc proteoglycans from different aged individuals were investigated. (1) The glycosaminoglycan content in the nucleus pulposus was greater than that in the annulus fibrosus at all ages. Glycosaminoglycan content increased from the infant to the young adult, and then decreased from the young to the mature adult. (2) Disc contained a higher content of hyaluronate than articular cartilage at all ages. (3) Proteolytically modified LP3 was predominant in the disc. (4) Very low link protein concentrations were observed in adult disc proteogl
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Naish, Claudia Martha. "Ultrasound imaging of the intervertebral disc." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288301.

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Molinari, Michael B. "Mechanical fractionation of the intervertebral disc." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:7385c54f-a3d0-4467-aca4-c7a9b8686982.

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Chronic lower back pain is a major public health problem, with direct and indirect economic costs comparable to those of heart disease, depression and diabetes. In many cases this pain derives from degeneration of the intervertebral disc (IVD), a fibrous, avascular tissue that sits between the vertebrae in the spinal column. A novel treatment approach for this ‘discogenic’ pain is the injection of a hydrogel that hybridises in situ and restores the normal biomechanical function of the disc. While a number of promising materials are currently under development, existing approaches to removing d
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Luxmoore, Bethany Jane. "Computational simulation of the intervertebral disc." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/4685/.

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The intervertebral disc is a complex structure unlike any other in the human body. The capability to withstand high loads and deformations in six degrees of freedom is facilitated by the unique soft tissue structures. However, the mechanical behaviour of these tissues is not well understood. The aim of this project was to investigate methods of deriving structural information about the tissues of the intervertebral disc for application in computational simulation, with particular focus on the mechanical function of the annulus fibrosis and how the behaviour of this tissue is governed by its su
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Jim, Jin-to. "Genetics and molecular characterization of degenerative disc disease." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B35720189.

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Chan, Kit-ying, and 陳潔瑩. "Development of whole disc organ culture system and acellular disc scaffold for intervertebral disc engineering." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45600077.

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Books on the topic "Intervertebral disc"

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Shapiro, Irving M., and Makarand V. Risbud, eds. The Intervertebral Disc. Springer Vienna, 2014. http://dx.doi.org/10.1007/978-3-7091-1535-0.

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Thacher, Christopher. Intervertebral disc disease. Edited by Kay William J and Brown Nancy O. J.B. Lippincott, 1989.

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M, Phillips Frank, and Lauryssen Carl, eds. The lumbar intervertebral disc. Thieme Medical Publishers, 2010.

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Colville, Gordon Malcolm Herbert. Enzymes of the intervertebral disc. University of Manchester, 1995.

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W, Hardy Russell, ed. Lumbar disc disease. 2nd ed. Raven Press, 1993.

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1940-, Ghosh P., ed. The Biology of the intervertebral disc. CRC Press, 1988.

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Grad, Sibylle, Mauro Alini, David Eglin, et al. Cells and Biomaterials for Intervertebral Disc Regeneration. Springer International Publishing, 2010. http://dx.doi.org/10.1007/978-3-031-02580-8.

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Postacchini, Franco. Lumbar disc herniation. Springer, 1999.

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1915-, Brown Joseph E., Nordby Eugene J, and Smith Lyman, eds. Chemonucleolysis. Slack, 1985.

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G, Watkins Robert, and Collis John S, eds. Lumbar discectomy and laminectomy. Aspen Publishers, 1987.

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Book chapters on the topic "Intervertebral disc"

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Cortes, Daniel H., and Dawn M. Elliott. "The Intervertebral Disc: Overview of Disc Mechanics." In The Intervertebral Disc. Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1535-0_2.

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Lasanianos, Nick G., George K. Triantafyllopoulos, and Spiros G. Pneumaticos. "Intervertebral Disc Herniation." In Trauma and Orthopaedic Classifications. Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6572-9_54.

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Crock, Henry Vernon. "Intervertebral Disc Calcification." In A Short Practice of Spinal Surgery. Springer Vienna, 1993. http://dx.doi.org/10.1007/978-3-7091-6650-5_4.

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Adams, Michael A. "Intervertebral Disc Tissues." In Engineering Materials and Processes. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03970-1_2.

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Eseonu, Kelechi, and Nicolas Beresford-Cleary. "Intervertebral Disc Anatomy." In Spine Surgery Vivas for the FRCS (Tr & Orth). CRC Press, 2022. http://dx.doi.org/10.1201/9781003201304-59.

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Shah, Akansha M., Sarah Yoon Ji Kwon, Wilson C. W. Chan, and Danny Chan. "Intervertebral Disc Degeneration." In Cartilage. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-45803-8_10.

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Lavignolle, B. "The Intervertebral Disc." In Spinal Anatomy. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20925-4_14.

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Brisson, Brigitte A. "Intervertebral Disc Fenestration." In Current Techniques in Canine and Feline Neurosurgery. John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781118711545.ch22.

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Shapiro, Irving M., and Makarand V. Risbud. "Introduction to the Structure, Function, and Comparative Anatomy of the Vertebrae and the Intervertebral Disc." In The Intervertebral Disc. Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1535-0_1.

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Yee, Anita, and Danny Chan. "Genetic Basis of Intervertebral Disc Degeneration." In The Intervertebral Disc. Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1535-0_10.

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Conference papers on the topic "Intervertebral disc"

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Chouhan, Aruna, Tarun Varma, and Rajendra Mitharwal. "Computer-Aided Diagnosis of Intervertebral Disc Herniation from Lumbar MRI." In 2024 9th International Conference on Communication and Electronics Systems (ICCES). IEEE, 2024. https://doi.org/10.1109/icces63552.2024.10859333.

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Bozorgpour, Afshin, Bobby Azad, Reza Azad, Yury Velichko, Ulas Bagci, and Dorit Merhof. "HCA-NET: Hierarchical Context Attention Network for Intervertebral Disc Semantic Labeling." In 2024 IEEE International Symposium on Biomedical Imaging (ISBI). IEEE, 2024. http://dx.doi.org/10.1109/isbi56570.2024.10635688.

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Maleskian, M., S. S. Park, and C. J. Hunter. "Experimental Modal Analysis of Intervertebral Disc Joint Dynamics." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-191699.

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The intervertebral discs provide mobility and a degree of shock absorbance to the spinal column. It has been shown that the mechanical properties of the intervertebral discs play an important role in their functionality [1, 2]. While static models of the intervertebral disc have significance, dynamic models characterize more accurately the in situ nature of the tissues. Some researchers [3] have studied dynamic disc loading from the perspective of biomedical performance and fatigue failure. Other studies have reported on the viscoelastic properties of discs under high frequency vibration [4].
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Hwang, David, Miao Yu, and Adam H. Hsieh. "Dependence of Intervertebral Disc Pressure Generation on Load History." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204233.

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It has been thoroughly documented that low back pain is often associated with deregulated biological function and compromised mechanical behavior of the intervertebral disc. Therefore, intervertebral disc mechanics have long been thought of as important factors both in driving cell-mediated processes involved in degeneration and in distinguishing between healthy versus degenerate discs. The nucleus pulposus is an integral part of the mechanics of the disc, the key property being its ability to pressurize to resist and distribute compressive stress to the annulus fibrosus and the endplates. The
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Kim, Jesse G., Tae-Hong Lim, Susan M. Renner, et al. "Experimental Intervertebral Disc Degeneration: Compressive Behavior Changes Over Time." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2611.

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Abstract Changes in axial compressive behavior of the intervertebral disc resulting from annulus stab wound were investigated using rabbit discs. Results of this study clearly showed that stabbing incision could cause disc degeneration with losses in disc height, elastic modulus, and energy dissipation capacity in 8 weeks after injury. Disc specimens obtained at 12 weeks after stab incision showed no further changes in disc height and axial compressive behavior from those found in 8 week specimens.
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Wiltsey, Craig, Thomas Christiani, Jesse Williams, et al. "Tissue Engineering of the Intervertebral Disc." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80349.

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Tissue engineering is a rapidly growing field of research that aims to repair damaged tissues within the body. Among tissue engineering approaches is the use of scaffolds to help regenerate lost tissues. Scaffolds provide structural support for specific areas within the body, namely load bearing regions, and allow for cells to be seeded within the scaffold for tissue regeneration. Scaffolds that specifically replicate the properties and/or composition of native tissues are referred to as biomimetic scaffolds.
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Lee, Cynthia R., Mauro Alini, and James C. Iatridis. "Organ Culture System for Mechanobiology Studies of the Intervertebral Disc." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-61248.

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The development of in vitro models is critical for furthering understanding of the intervertebral disc and the development of disc regeneration/tissue engineering. An in vitro culture system targeted towards mechano-biology studies of the intervertebral disc (IVD) was built and validated using bovine coccygeal discs. Discs were maintained in culture for up to one week with and without vertebral endplates. Water content and glycosaminoglycan content were found to be stable and cells were metabolically active when cultured under a 5kg static load.
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Kumaresan, Srirangam, Frank A. Pintar, Narayan Yoganandan, Phaladone J. Khouphongsy, and Joseph F. Cusick. "Intervertebral Disc Morphology in Cervical Spine Biomechanics." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0464.

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Abstract Although qualitative descriptions of degenerative changes in the intervertebral disc components have been reported, methods to quantify these changes are lacking. A methodology was developed in this study to quantify the three-dimensional geometrical variations of the annulus fibrosus and nucleus pulposus. Fresh isolated intervertebral discs with adjacent vertebral bodies of skeletally mature young and old adult primates were sectioned sequentially, and different staining methods were used to distinguish the annulus and nucleus. Histological images were examined using light microscopy
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Colliou, Olivier K., Ellen Liebenberg, Neil A. Duncan, and Jeffrey C. Lotz. "Compression-Induced Intervertebral Disc Degeneration in a Mouse Model." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0279.

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Abstract While the cause of low-back pain is unknown in many patients, a significant percentage is thought to be due to degeneration of the intervertebral disc1. Because of the severe structural demands placed on the spine, and the epidemiological association between physical activity and disc degeneration, mechanical forces are thought to be a central etiologic factor. Therefore, precise knowledge of the cascade of biologic events associated with disc degeneration, and the means by which they are coupled to physical loading, would be invaluable for developing improved guidelines for maintaini
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Natarajan, Raghu N., Mohammed Qasim, Howard An, and Gunnar B. J. Andersson. "Effect of Annular Micro Tear on Lumbar Intervertebral Disc Biomechanics." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19025.

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Structural alterations of the disc are accompanied by changes in disc tissue structure and composition during degeneration processes. Human cadaver studies have shown that the probability of presence of annular tear is 0.6 in the age group 30 to 34 which increases to 0.85 in the 60 year age group. Among different phenomena that occur during disc degeneration, annular radial tears are commonly associated with disc herniations. The effect of increase in size of radial micro tear in the lumbar discs on the change in biomechanics of the disc is an area where there is very little information curren
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Reports on the topic "Intervertebral disc"

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Smith, Paul N., David R. J. Gill, Michael J. McAuliffe, et al. Demographics of Spinal Disc Arthroplasty: Supplementary Report. Australian Orthopaedic Association, 2023. http://dx.doi.org/10.25310/yjor3105.

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The 2023 Demographics of Spinal Disc Arthroplasty Supplementary Report is based on the analysis of 11,343 spinal disc procedures recorded by the Registry with a procedure date up to and including 31 December 2022. This supplementary report provides summary data and demographic information on spinal disc replacement surgery. Data are broken down into the five classes of spinal disc replacement: spinal segment, spinal ball trough, insert and endplate, cervical intervertebral disc and lumbar intervertebral disc. Revision rates are not provided for spinal disc replacement. The Spinal Disc Arthropl
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Lewis, Peter L., David RJ Gill, Michael J. McAuliffe, et al. Demographics of Spinal Disc Arthroplasty: 2024 Supplementary Report. Australian Orthopaedic Association, 2024. http://dx.doi.org/10.25310/kuzs3460.

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The 2024 Demographics of Spinal Disc Arthroplasty Supplementary Report is based on the analysis of 12,478 spinal disc procedures recorded by the Registry with a procedure date up to and including 31 December 2023. This supplementary report provides summary data and demographic information on spinal disc replacement surgery. Data are broken down into the five classes of spinal disc replacement: spinal segment, spinal ball trough, insert and endplate, cervical intervertebral disc and lumbar intervertebral disc. Revision rates are not provided for spinal disc replacement. The Spinal Disc Arthropl
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Snyder, Brian. Development of Ultrasound to Measure In-vivo Dynamic Cervical Spine Intervertebral Disc Mechanics. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada600493.

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Duan, Jiahao, Shaofeng Yang, Zhaoyong LI, Long Chen, and Ran Teng. Treatment of lumbar intervertebral disc herniation by invigorating kidney and promoting blood Circulation:A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.3.0080.

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Guo, Tianci, Huichuan Feng, Aifeng Liu, Jixin Chen, and Weijie Yu. Efficacy and safety of percutaneous endoscopic lumbar discectomy via intervertebral approach for L5/S1 lumbar disc herniation: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.7.0073.

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Li, Wenhao, He Zhao, Zhencheng Xiong, et al. Evaluation of the efficacy of stem cell therapy in animal models of intervertebral disc degeneration based on imaging indicators: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0148.

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Li, Jiaqi, PWH Kwong, MYL Chan, and M. Kawabata. Comparison of in vivo intradiscal pressure between sitting and standing in human lumbar spine: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.3.0043.

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Review question / Objective: The primary objective of this systematic review is to compare the differences in vivo IDP between sitting and standing postures. The secondary objective of this review is to compare effect size estimates between 1) dated and more recent studies and 2) healthy and degenerated intervertebral discs. Condition being studied: Healthy adults, patients with low back pain. Eligibility criteria: Studies were included in the review if they 1) involved in vivo IDP measurement in both sitting and standing postures, 2) involved measurements with intervertebral body replacement
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A GLP Chronic Study to Evaluate the Biological Effects and Systemic Toxicity of Rejuve (IDSD) Implantation in an Ovine Intervertebral Disc Model. Spinal Simplicity LLC, 2018. http://dx.doi.org/10.57212/emyn8297.

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