To see the other types of publications on this topic, follow the link: Intestinal Perforation.
Journal articles on the topic 'Intestinal Perforation'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Intestinal Perforation.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Donahue, Laura. "Spontaneous Intestinal Perforation." Neonatal Network 26, no. 5 (2007): 335–51. http://dx.doi.org/10.1891/0730-0832.26.5.335.
Full textAbstract:
SPONTANEOUS INTESTINAL perforations (SIPs) have been documented to occur in as many as 8.4 percent of very low birth weight (VLBW) newborns.1Gastrointestinal (GI) perforations first appeared in the literature in 1825 when Siebold described a gastric perforation in an estimated 34-week-gestational-age infant.2Thelander in 1939 described the first cases of spontaneous perforation in three stillborn infants as perforations proximal to the ileocecal valve.3
2
Hafsi, Montacer, Marwa Moussi, Asma Zouaghi, et al. "Intestinal incarceration following aspiration evacuation: A case report." Edorium Journal of Gynecology and Obstetrics 9, no. 1 (2024): 5–8. http://dx.doi.org/10.5348/100035g06mh2024cr.
Full textAbstract:
Uterine perforation is a frequently overlooked complication of operative procedures. The incidence of perforation is estimated to range from 1 to 4 per 1000 during curettages for pregnancy termination. Reported complications include uterine, digestive, and vesical perforations, hemorrhage, endometritis, and secondary infertility. However, intestinal incarceration after uterine perforation remains extremely rare. We present a case of uterine perforation occurring after an aspiration curettage, complicated by digestive incarceration.
3
Li, Zhi-Wang, Tao-Feng Jiang, Cheng-Kun Yang, Zhi-Jie Xu, Wen-Biao Zhu, and En Li. "Recurrent small intestinal perforation from gastric mucosal heterotopia: A case report." World Journal of Gastrointestinal Surgery 16, no. 12 (2024): 3857–61. http://dx.doi.org/10.4240/wjgs.v16.i12.3857.
Full textAbstract:
BACKGROUND Gastric mucosal heterotopia (GMH) is a rare, typically asymptomatic condition characterized by ectopic gastric mucosa in tissues outside the stomach. However, it can lead to severe complications, including small intestinal perforation. This case report highlights the unique clinical presentation of GMH-induced recurrent small intestinal perforations, which has been rarely documented. These findings emphasize the importance of considering GMH in patients with unexplained recurrent gastrointestinal perforations. CASE SUMMARY A 13-year-old female presented with acute abdominal pain. Her medical history included four prior surgeries for small intestinal perforations. Enhanced computed tomography revealed localized bowel thickening and perforation, prompting emergency surgery. A 20 cm segment of the ileum was resected and anastomosed. Pathological analysis confirmed extensive GMH with ulceration and perforation, identifying GMH as the cause of the recurrent perforations. Postoperatively, the patient recovered well with no recurrence by the 10-month follow-up. CONCLUSION GMH should be considered in cases of recurrent unexplained intestinal perforations.
4
Masood, Irfan, Zain Majid, Ali Rafiq, Waqas Rind, Aisha Zia, and Sajjad Raza. "Multiple, Pan-Enteric Perforation Secondary to Intestinal Tuberculosis." Case Reports in Surgery 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/318678.
Full textAbstract:
Free perforation is one of the most feared complications of the intestinal tuberculosis. The terminal ileum is the most common site of perforation, while the majority of (90%) perforations are solitary. Herein, we describe a case of a 25-year-old male who presented with generalized peritonitis requiring an emergency exploratory laparotomy, which revealed pan-enteric perforation characterized by multiple perforations of the small bowel extending 10–15 cm from the DJ flexure up to the terminal ileum. The perforations were primarily closed, while 6–8 cm of the diseased terminal ileum was resected and the two ends were brought out as double-barreled ostomy. To the best of our knowledge, such an extensive tuberculous perforation of the small bowel has not been previously reported in the literature before.
5
Olgemoeller, Franziska, Jonathan J. Waluza, Dalitso Zeka, et al. "Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi." Clinical Infectious Diseases 71, Supplement_2 (2020): S96—S101. http://dx.doi.org/10.1093/cid/ciaa405.
Full textAbstract:
Abstract Background Typhoid fever remains a major source of morbidity and mortality in low-income settings. Its most feared complication is intestinal perforation. However, due to the paucity of diagnostic facilities in typhoid-endemic settings, including microbiology, histopathology, and radiology, the etiology of intestinal perforation is frequently assumed but rarely confirmed. This poses a challenge for accurately estimating burden of disease. Methods We recruited a prospective cohort of patients with confirmed intestinal perforation in 2016 and performed enhanced microbiological investigations (blood and tissue culture, plus tissue polymerase chain reaction [PCR] for Salmonella Typhi). In addition, we used a Poisson generalized linear model to estimate excess perforations attributed to the typhoid epidemic, using temporal trends in S. Typhi bloodstream infection and perforated abdominal viscus at Queen Elizabeth Central Hospital from 2008–2017. Results We recruited 23 patients with intraoperative findings consistent with intestinal perforation. 50% (11/22) of patients recruited were culture or PCR positive for S. Typhi. Case fatality rate from typhoid-associated intestinal perforation was substantial at 18% (2/11). Our statistical model estimates that culture-confirmed cases of typhoid fever lead to an excess of 0.046 perforations per clinical typhoid fever case (95% CI, .03–.06). We therefore estimate that typhoid fever accounts for 43% of all bowel perforation during the period of enhanced surveillance. Conclusions The morbidity and mortality associated with typhoid abdominal perforations are high. By placing clinical outcome data from a cohort in the context of longitudinal surgical registers and bacteremia data, we describe a valuable approach to adjusting estimates of the burden of typhoid fever.
6
Torosian, M. H., and A. D. Turnbull. "Emergency laparotomy for spontaneous intestinal and colonic perforations in cancer patients receiving corticosteroids and chemotherapy." Journal of Clinical Oncology 6, no. 2 (1988): 291–96. http://dx.doi.org/10.1200/jco.1988.6.2.291.
Full textAbstract:
Thirty patients with lymphoma (12), leukemia (two), myeloma (one), or metastatic solid tumors (15) were explored for 31 episodes of spontaneous intestinal perforation during an 11-year period at Memorial Sloan-Kettering Cancer Center. Twenty-three patients (76.6%) were receiving corticosteroids alone or in combination with chemotherapy and seven patients (23.4%) were receiving chemotherapy alone at the time of perforation. Fourteen perforations (45%) occurred in the small intestine and 17 perforations (55%) occurred in the colon. Malignancy was histologically demonstrated at the site of perforation in 16 patients (52%). Twenty major postoperative complications occurred in 15 patients (50%) and the operative mortality rate was 53%. Factors such as age, sex, duration or type of symptoms, site of perforation, malignancy at the site of perforation, peripheral leukocyte count, and serum albumin and total protein levels were not significantly related to patient survival. Early diagnosis and aggressive surgical intervention is essential to improve survival following intestinal perforation in this high-risk population.
7
H. B., Shashikumar, Madhu B. S., and Shyama S. "Gastro intestinal perforations: an audit from a tertiary care teaching hospital, Mysore, India." International Surgery Journal 5, no. 11 (2018): 3484. http://dx.doi.org/10.18203/2349-2902.isj20184613.
Full textAbstract:
Background: Peritonitis secondary to hollow viscus perforation is one of the most frequently encountered surgical emergencies in India. The objective of this study was to study the demographic and clinical profile of gastro intestinal perforations and surgical procedures done for the same in a tertiary care teaching hospital.Methods: This study was performed on 46 cases of hollow viscus perforation admitted in K. R. Hospital from January to June 2018. The presenting symptoms, age and sex profile, risk factors, site of perforation, the surgical procedure they underwent, post-operative complications were assessed and analyzed.Results: The most common age group affected was 21-30 years out of which 89.1 % were males. Gastric perforations were the most common type (56.5%) and jejunal perforations were the least common (6.5%). Abdominal pain was the main presenting symptom in all the cases. Fever was found to be a significant history in cases of ileal perforation (p=0.001) as was history of trauma in cases of jejunal perforation (p=0.001). Guarding, rigidity and air under the diaphragm were seen consistently in most cases. Graham’s patch repair was the most common surgical procedure performed. Ileostomy was the most common surgery done for ileal perforations. Wound infections were the most common post-operative complication observed and death occurred in 13% of cases mostly due to sepsis and cardio pulmonary complications.Conclusions: This study showed an increased incidence of perforation in younger age group which is alarming. The rise in the frequency of gastric perforations points towards an unhealthy lifestyle and dietary habits.
8
Nicolodi, Gabriel Cleve, Cesar Rodrigo Trippia, Maria Fernanda F. S. Caboclo, et al. "Intestinal perforation by an ingested foreign body." Radiologia Brasileira 49, no. 5 (2016): 295–99. http://dx.doi.org/10.1590/0100-3984.2015.0127.
Full textAbstract:
Abstract Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation.
9
Lipatov, V. A., V. P. Gavrilyuk, D. A. Severinov, and O. V. Padalkina. "Simulation of intestinal perforation in experiment." Experimental and Clinical Gastroenterology, no. 6 (October 22, 2024): 139–44. http://dx.doi.org/10.31146/1682-8658-ecg-226-6-139-144.
Full textAbstract:
The current problem of neonatal and pediatric surgery remains the tactics of surgical treatment and postoperative management of patients with perforated peritonitis. Mortality with perforation of the stomach and intestines in children in the newborn period reaches about 40-80 %. The combination of the syndrome of increased intra-abdominal pressure and multiple organ failure causes the extremely serious condition of patients. In this connection, new approaches to the surgical treatment of such patients are currently being actively developed. For this, new medical devices are tested in experimental practice, but the problem of such studies, first of all, lies in the lack of an adequate model of the pathological process. The aim of the work is to analyze the methods of experimental modeling of intestinal perforations described in the public domain. For this, a study was conducted of the most significant scientific publications of such databases as Google Scholar, PubMed, Scopus, eLIBRARY. The present work provides a detailed description of existing options for modeling perforations of various parts of the gastrointestinal tract (stomach, small intestine and colon), depending on the goals of the experiment. Several rather rare techniques based on the introduction of microorganisms are also presented. In addition, the article describes the method proposed by the authors for modeling perforation using laparoscopic access.
10
Abhishek, Jain, Jain Trilok, Kumar Badaya Dinesh, and Jain Vinita. "Assessment of the Surgical Profile among Patients of Gastro-Intestinal Tract Perforation." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 786–89. https://doi.org/10.5281/zenodo.11221453.
Full textAbstract:
Background: Gastrointestinal tract perforation occurs when pathology of any specific disease involves the entire depth of the gastrointestinal tract. Gastrointestinal tract perforation leads to the contamination of peritoneal cavity with intestinal contents. According to previous researches it was reported that perforations can be occurred anywhere in full length of gastrointestinal tract. Material & Methods: Patients who were diagnosed as perforation and peritonitis on the basis of laboratory diagnosis and clinical examination were enrolled by simple random sampling. Clearance from Institutional Ethics Committee was taken before start of study. Written informed consent was taken from each study participant. Results: In the present study, out of total study participants abdominal pain was the most common presenting symptom present in patients which was followed by fever, abdominal distension and vomiting. On the basis of time of perforation, 10% cases presented within12 hour, between 12 and 24 hour was reported among in 50% cases, in the rage of 24 and 48 hour seen in 20% patients, in the range of 48 and 72 hour reported in 10% cases, in range of 72 and 96 hour reported in10% cases. Near about all patients were operated in the range of 12 hours of hospitalization. We found that majority of cases had circular perforation of typhoid at antimesenteric border which was followed by tubercular elliptical perforation on the antimesenteric border and traumatic type perforation. Conclusion: The most common presenting symptoms present among patients were abdominal pain, abdominal distension, vomiting, fever and obstipation. We found that majority of cases had circular perforation of typhoid at an times enteric border which was followed by tubercular elliptical perforation on the antimesenteric border and traumatic type perforation. Keywords: Gastro-intestinal tract perforation, signs and symptoms, presentation.
11
Pijpers, Adinda G. H., Ramon R. Gorter, Laurens D. Eeftinck Schattenkerk, et al. "Identifying Preoperative Clinical Characteristics of Unexpected Gastrointestinal Perforation in Infants—A Retrospective Cohort Study." Children 11, no. 5 (2024): 505. http://dx.doi.org/10.3390/children11050505.
Full textAbstract:
Infants presenting with unexpected pneumoperitoneum upon abdominal X-ray, indicating a gastrointestinal perforation (GIP), have a surgical emergency with potential morbidity and mortality. Preoperative determination of the location of perforation is challenging but will aid the surgeon in optimizing the surgical strategy, as colon perforations are more challenging than small bowel perforations. Therefore, the aim of this study is to provide an overview of preoperative patient characteristics, determine the differences between the small bowel and colon, and determine underlying causes in a cohort of infants with unexpected GIP. Methods: All infants (age ≤ 6 months) who presented at our center with unexpected pneumoperitoneum (no signs of pneumatosis before) undergoing surgery between 1996 and 2024 were retrospectively included. The differences between the location of perforation were analyzed using chi-squared and t-tests. Bonferroni correction was used to adjust for multiple tests. Results: In total, 51 infants presented with unexpected pneumoperitoneum at our center, predominantly male (N = 36/51) and premature (N = 40/51). Among them, twenty-six had small bowel, twenty-two colon, and three stomach perforations. Prematurity (p = 0.001), birthweight < 1000 g (p = 0.001), respiratory support (p = 0.001), and lower median arterial pH levels (p = 0.001) were more present in patients with small bowel perforation compared with colon perforations. Pneumatosis intestinalis was more present in patients with colon perforation (p = 0.004). All patients with Hirschsprung disease and cystic fibrosis had colon perforation. The final diagnoses were mainly focal intestinal perforations (N = 27/51) and necrotizing enterocolitis (N = 9/51). Conclusion: Infants with unexpected GIP, birthweight <1000 g, and prematurity have more risk for small bowel perforation. In case of colon perforation, additional screening (for Hirschsprung and cystic fibrosis) should be considered.
12
Sharma, AK, RK Sharma, SK Sharma, A. Sharma, and D. Soni. "Typhoid intestinal perforation: 24 Perforations in one patient." Annals of Medical and Health Sciences Research 3, no. 5 (2013): 41. http://dx.doi.org/10.4103/2141-9248.121220.
Full text
13
The', T. G., M. Young, and S. Rosser. "Localized Intestinal Perforation." Pediatrics 94, no. 5 (1994): 776. http://dx.doi.org/10.1542/peds.94.5.776.
Full textAbstract:
We read with pleasure Buchheit's1 article comparing the clinical findings in 21 preterm infants with localized intestinal perforation (LP) versus those of 21 preterm infants with intestinal perforation secondary to necrotizing enterocolitis (NEC). However, we would be grateful if the authors would clarify two points: 1. How are their 21 cases of LP different from the &gt;500 cases of idiopathic gastrointestinal perforation reviewed by Lloyd in 1979?2 2. The authors hypothesized that the placement of midthoracic umbilical artery catheters (UACs) would be a significant factor in the etiology of LP.
14
Yadav, Bhanwar L., Somendra Bansal, Shalu Gupta, and Pradeep K. Verma. "Incidence and management of intestinal perforation in typhoid: a prospective, observational study." International Surgery Journal 7, no. 5 (2020): 1570. http://dx.doi.org/10.18203/2349-2902.isj20201871.
Full textAbstract:
Background: Intestinal perforation is a common surgical problem, which need proper attention. Typhoid is the most common cause of bowel perforation. With the concept of a correct diagnosis of perforation in reference to its etiology and further study of etiological factor (typhoid) in relation to epidemiology, surgical treatment and outcome, the present study has been undertaken.Methods: It is a prospective, observational study in which 50 cases of enteric perforation admitting in SMS Hospital at JAIPUR were observed. All patients of enteric perforation peritonitis were evaluated by detailed history, clinical examination and radiological as well as laboratory investigations. After initial resuscitation patient were treated by operative procedures. Postoperatively progress report, morbidity and mortality data were observed.Results: Mean age of patients was 26.38 years. Male to female ratio was 4:1. Enteric perforation is more common in patients with poor nutritional status and rural area. Primary repair of perforation was done in patient with small perforation with relatively healthy bowel, while ileostomy was done in patients with large perforation of longer duration, multiple perforations and edematous bowel with necrotic patches. Mortality was highest in patients who underwent primary repair and proximal loop ileostomy (33.3%) and lowest in patients in which exteriorization of the perforation as loop ileostomy was done (10.3%).Conclusions: The time interval between occurrence of perforation and starting of specific therapy is the most important factor in deciding the ultimate outcome of the typhoid perforation patient and operative procedure is another important factor in deciding the outcome.
15
Buchheit, John Q., and Dan L. Stewart. "Clinical Comparison of Localized Intestinal Perforation and Necrotizing Enterocolitis in Neonates." Pediatrics 93, no. 1 (1994): 32–36. http://dx.doi.org/10.1542/peds.93.1.32.
Full textAbstract:
Objective. To better define the prognosis of neonates with gastrointestinal perforation and improve their management. Methods. We reviewed the results of physical examinations, laboratory results, and radiographic tests of 42 patients in whom gastrointestinal perforation was diagnosed in our neonatal intensive care unit. Results. Twenty-one patients had necrotizing enterocolitis and 21 had localized intestinal perforation. Perinatal history, gender, race, birth weight, and estimated gestational age were similar for both groups. Patients with localized perforation were more likely to have had an umbilical artery catheter in place within 48 hours of perforation, to have received higher doses of indomethacin, to have undergone primary surgical repair, and to have survived until discharge from the hospital. Patients with necrotizing enterocolitis were more likely to have received enteral feedings and to have had a metabolic acidosis and leukopenia at the time the perforation was diagnosed. Conclusions. We conclude that localized intestinal perforation and necrotizing enterocolitis, although similax in the organ system they affect, are distinctly different in clinical correlates and outcome. The increased awareness of localized perforations may help those taking care of neonates to diagnose this condition more accurately and to discuss its implications with family members.
16
Shamsi, Saeedeh, Reza Shah Hosseini, Seyyedabbas Pakmehr, Sadaf Mottaghian, and Sepideh Karkon Shayan. "Retroperitoneal Rectal Perforation Due to Pomegranate Seed Bezoar: A Rare Case." Cognizance Journal of Multidisciplinary Studies 4, no. 4 (2024): 151–56. http://dx.doi.org/10.47760/cognizance.2024.v04i04.007.
Full textAbstract:
Various causes are involved in rectal perforation aetiology, including: Iatrogenic perforations, traumatic perforations, malignant or diverticular disease perforations, stercoral perforations, and idiopathic perforations. Rectosigmoid perforations are life-threatening and require immediate diagnosis and surgical treatment. Bezoars are accumulations of indigestible foreign matter that accumulate in the gastrointestinal tract. Seed vesicles are a subset of phytobizzars produced by plant seeds or undigested fruit kernels. Most Intestinal bezoura occur in the rectum, causing constipation or nonspecific abdominal or rectal pain. The following is a report of a case of pomegranate seeds in the rectum that resulted in retroperitoneal rectal perforation.
17
Saeedeh, Shamsi, Shah Hosseini Reza, Pakmehr Seyyedabbas, Mottaghian Sadaf, and Karkon Shayan Sepideh. "Retroperitoneal Rectal Perforation Due to Pomegranate Seed Bezoar: A Rare Case." Cognizance Journal of Multidisciplinary Studies (CJMS) 4, no. 4 (2024): 151–56. https://doi.org/10.47760/cognizance.2024.v04i04.007.
Full textAbstract:
Various causes are involved in rectal perforation aetiology, including: Iatrogenic perforations, traumatic perforations, malignant or diverticular disease perforations, stercoral perforations, and idiopathic perforations. Rectosigmoid perforations are life-threatening and require immediate diagnosis and surgical treatment. Bezoars are accumulations of indigestible foreign matter that accumulate in the gastrointestinal tract. Seed vesicles are a subset of phytobizzars produced by plant seeds or undigested fruit kernels. Most Intestinal bezoura occur in the rectum, causing constipation or nonspecific abdominal or rectal pain. The following is a report of a case of pomegranate seeds in the rectum that resulted in retroperitoneal rectal perforation.
18
Chhoun, Christopher, Lucy Joo, Brian Blair, Yaser Khalid, Neethi Dasu, and Rahul Patel. "INTESTINAL PERFORATIONS IN PATIENTS WITH IBD: AN ANALYSIS OF THE NATIONAL INPATIENT SAMPLE 2015-2019." Inflammatory Bowel Diseases 29, Supplement_1 (2023): S73. http://dx.doi.org/10.1093/ibd/izac247.141.
Full textAbstract:
Abstract BACKGROUND Inflammatory Bowel Disease results in numerous complications due to inflammatory damage to the intestinal mucosa. One complication of IBD is perforation of the intestines. The aim of our study was to study the impact of IBD on clinical outcomes in patients with intestinal perforation. METHODS The Nationwide Inpatient Sample (NIS) database encompasses approximately 7 million inpatient hospitalizations annually in the United States. Data were extracted from the National Inpatient Sample (NIS) Database for the years 2015-2019. Patients aged 18 years and above with diagnoses of IBD and intestinal perforation were identified using ICD codes. Multivariate regression analysis was used to estimate the odds ratios of in-hospital mortality, the average length of hospital stay (LOS), and hospital charges using STATA 17. Multivariate logistic and linear regression analysis was used accordingly to adjust for confounders. RESULTS We identified 221,820 patients with IBD of which 43,509 patients were matched to those with intestinal perforations. Average age was 56.61 years. There was a significant increase in inpatient mortality (OR 3.10, CI 2.06-4.67, p&lt;0.0001), total cost of hospitalization ($140,391, CI 108,576.3 - 172,205.9, p&lt;0.0001), and hospital length of stay (9.42 days, CI 7.67 - 11.2, p&lt;0.0001) in patients with IBD with a concurrent diagnosis of intestinal perforation when compared to IBD patients without intestinal perforations. On multivariate analysis, positive predictors of mortality were Acute Kidney Injury (AKI) (OR: 3.734811 p-value: &lt;0.001; 95% CI: 3.159078 - 4.41547) and sepsis (OR: 5.616263 p-value: &lt;0.001; 95% CI: 4.777288- 6.602577). LOS was increased in patients with hospitalizations complicated by AKI (OR 2.577361; p-value: &lt;0.001; 95% CI: 2.327294-2.827427) and sepsis (OR 3.096738; p-value: &lt;0.001; CI: 2.754462- 3.439013). Total hospital charges were increased in patients with hospitalizations complicated by sepsis ($41,685.55; p-value: &lt;0.001; 95% CI: 35,262.58-48,108.52) and AKI ($34,990.15; p-value: &lt;0.001; CI: $30,215.96-39,764.34). CONCLUSIONS Our study demonstrates the presence of intestinal perforations in hospitalized patients with IBD is associated with poor outcomes in terms of mortality, length of stay, and total hospital charges. Furthermore it was found that the presence of both sepsis and AKI are also associated with worsened outcomes. Our study is novel because there are minimal data that investigate the clinical outcomes associated with IBD patients with intestinal perforations. Our study demonstrates that the presence of intestinal perforations poses a significant mortality risk in these patients, along with concurrent sepsis and AKI.Further studies would be beneficial to identify further risk factors contributing to worsening outcomes.
19
Natarajan, Saravanan, Shankar Mohan, Sulthana Dhilras, Jameel Ahmed, and Selvakumar Mariappan. "Perforations of Gastro Intestinal Tract in Neonates: A Retrospective Study of Aetiological Factors Excluding Necrotising Enterocolitis." Journal of Neonatal Surgery 8, no. 2 (2019): 11. http://dx.doi.org/10.47338/jns.v8.345.
Full textAbstract:
Background: Perforations of the Gastro Intestinal Tract (PGIT) in neonates, postnatally, apart from Necrotising Enterocolitis (NEC) as aetiological factor, though less common, are well known.Materials and Methods: Neonates presenting with PGIT, excluding NEC, were analyzed in this retrospective study, over a period of three years in a tertiary care centre.Results: Of 20 neonates presented with PGIT, during study tenure, 8 were due to non-NEC related causes. The site of perforation was stomach, ileum, cecum, colon, and rectum. The usual causes of PGIT in the neonates were spontaneous perforations and perforations secondary to mechanical obstruction. Patients underwent surgery with good outcome.Conclusions: PGIT in neonates due to aetiological factors apart from NEC, have better outcome, than those with NEC. The other causes of PGIT are spontaneous perforation, intestinal atresia, Hirschsprung’s disease, anorectal malformations etc.
20
Abdurrazzaaq, Abdussemee Idowu, Vechu Grimah, and Ahmed Ashuku Yakubu. "Outcome of Typhoid Intestinal Perforation Management in a Tertiary Hospital, North-Central Nigeria." European Journal of Medical and Health Sciences 5, no. 3 (2023): 30–34. http://dx.doi.org/10.24018/ejmed.2023.5.3.1634.
Full textAbstract:
Background: Typhoid intestinal perforation is the most common surgical complication and a significant cause of morbidity and mortality in typhoid fever.
 Aim: To determine the treatment outcome of patients with typhoid intestinal perforation.
 Methods: A single-centre retrospective study involving retrieving case notes of all consecutive patients who had surgeries for peritonitis secondary to typhoid intestinal perforation from October 2016 to September 2017. Data were collected with a designed case report form and analysed.
 Results: Sixty-nine patients had surgeries for typhoid intestinal perforation, of which forty-five (65.2%) were males. The median (range) age of the participants was 10(4-44) years. The commonest complications were surgical site infections 49 (71%) and wound dehiscence 17 (24.6%). The median (range) post-operative hospital stay among the survivors was 13 (7 – 50) days. Enterocutaneous fistula and wound dehiscence were responsible for prolonged hospital stay (x2= 30.126, p value< 0.001 and x2= 45.777, p value< 0.001 respectively). The overall mortality rate was 19 (27.5%). Under-five children had the highest mortality rate 5/15 (33.3%). Mortality was found to be more common among females though the association was not statistically significant (p value = 0.052). Mortality was significantly associated with extended surgical procedures (p value= 0.027). 
 Conclusion: The reported cases of typhoid intestinal perforations at the study centre were high but the mortality rate was comparable to other similar studies in Nigeria. Mortality from typhoid perforation remains high, and the pathology is best prevented
21
Kidwai, Roman, Ravi Kumar Baral, and Anup Sharma. "Analysis of Intra-Abdominal Pressure in Obstructive and Perforative Lesions of Gastro-Intestinal Tract." Journal of Nepalgunj Medical College 16, no. 2 (2018): 31–34. http://dx.doi.org/10.3126/jngmc.v16i2.24871.
Full textAbstract:
Introduction: Abdominal Compartment syndrome is an emerging problem in surgical patients with significant mortality reaching up to 100% in untreated patients. Intra abdominal hypertension (IAH) and abdominal compartment syndrome is common finding in traumatic and critically ill surgical patients. There are sporadic case reports in literature of intra abdominal hypertension & abdominal compartment syndrome in general surgical patients, particularly in obstructive and perforative diseases of gastrointestinal tract (GIT). This study was done to know the pattern of intraabdominal pressure (IAP) and effect of intra abdominal hypertension (IAH) in obstructive and perforative lesions of gastrointestinal tract.
 Materials and Method: A total number of 145 cases were included between November 2016 to October 2017. These patients were from the department of Suregery, Nepalgunj Medical College, who underwent Surgery due to the Intestinal Obstruction or perforation.
 Result: There were total 145cases. The incidence of IAH in patients with intestinal obstruction and perforation peritonitis at presentation was 68.27%. 65 (66.32%) out of 98patients with perforation peritonitis had IAH and 34 (72.34%) with intestinal obstruction among 47 had IAH before surgery. There were 2.12% patients with abdominal compartment syndrome (ACS) in obstruction and 3.06% in perforation; ACS was highest amongst traumatic perforation population accounting for 13.33% of traumatic cases. There was statistically significant derangement (p-value<0.05) of organ function with raised IAP which showed marked improvement following surgery. Four patients died, all these patients had ACS at the time of presentation.
 Conclusion: IAH is a significant entity in obstructive and perforative lesions of GIT. ACS can occur in obstructive and perforative lesions of GIT with significant mortality.
22
Shrimanker, Nikhita, Nathan P. Heller, Fabiola Souza, and Daniel E. Kim. "Late anastomotic perforation of the ileum 3 years after intestinal resection." BMJ Case Reports 17, no. 8 (2024): e260668. http://dx.doi.org/10.1136/bcr-2024-260668.
Full textAbstract:
Late perforation of the ileum is a rare and potentially life-threatening complication following intestinal resection. We present a unique case of a woman in her 60s with a history of appendiceal carcinoid tumour, who underwent a right hemicolectomy. Positron emission tomography and surveillance CTs showed normal surgical changes and no recurrent malignancy. Three years postoperatively, she presented with severe abdominal pain. CT revealed a perforation along the ileal wall of the ileocolonic anastomosis. She underwent emergent resection and repeat ileocolonic anastomosis. We conclude that the patient had subclinical ischaemia of the anastomosis, which eventually progressed to perforation 3 years later. We discuss a literature review on late small intestinal anastomotic perforations and their associated risk factors. Our case and literature review emphasise the importance of considering delayed anastomotic leak in postoperative patients with a history of intestinal cancer, inflammatory bowel disease, Roux-en-Y enteroenterostomy or side-to-side anastomosis.
23
Poornima, Rangappa, K. L. Venkatesh, Goutham M. V., Nirmala, and Noorulla Hassan. "Clinicopathological study of Ileal perforation: study in tertiary center." International Surgery Journal 4, no. 2 (2017): 543. http://dx.doi.org/10.18203/2349-2902.isj20164796.
Full textAbstract:
Background: The objective of this study was to evaluate the clinicopathological characteristics in Ileal perforations because of confusion and controversy over the diagnosis and optimal surgical treatment of terminal Ileal perforation -a cause of obscure peritonitis. Perforation of terminal ileum is a cause for obscure peritonitis with severe toxic state, there may be obscured clinical features with resultant delays in diagnosis and adequate surgical intervention.Methods: A prospective study was conducted in Victoria Hospital and Bowring and Lady Curzon Hospital attached to Bangalore Medical College and Research Institute over a period of 5 years from June 2011 to May 2015. A total of 136 patients presented in this period with hollow viscus perforation and out of these 64 patients had Ileal perforation alone on exploratory laparotomy. Ileal perforations account for about 20 percent of all cases of hollow viscus perforation. Emergency exploratory laparotomy was done and perforation was identified, edge biopsy was taken in all cases and the perforation was closed in two layers and resection anastomosis was done in stricture with perforation. Histopathological report was reviewed following surgery.Results: A total of 64 patients with Ileal perforation were included in the study of which 52 were males and 12 were females accounting for 81.25 percent and 18.75 percent respectively. The causes for perforation were enteric fever (82.81%), nonspecific inflammation (9.38%), and tuberculosis (7.81%). Simple closure of the perforation (74.58%) and the remaining primary resection and anastomosis were the mainstay of the surgical management.Conclusions: The common pathology of Ileal perforation is Typhoid or Enteric fever, Non-specific ulcer, Tuberculosis and others. Intestinal complications of typhoid fever are quite common in developing countries. Nonspecific inflammation of the terminal ileum was other predominant cause operative findings were similar to that of typhoid fever but no laboratory evidence of the disease was found. Intestinal tuberculosis can mimic many conditions.
24
Ali Almoamin, Haithem H. "Review of 31 cases of neonatal gastrointestinal perforations." Journal of the Faculty of Medicine Baghdad 58, no. 2 (2016): 121–25. http://dx.doi.org/10.32007/jfacmedbagdad.582221.
Full textAbstract:
Background: Despite the recently improved neonatal intensive management, gastrointestinal perforation during the neonatal period is still a major challenge for pediatric surgeons.Objective: To review the effects of different clinical and operative parameters on the mortality of neonatal intestinal perforations.Patients and Methods: A retrospective study was done to 31 cases of neonatal intestinal perforation at the neonatal intensive care unit of Basrah children speciality hospital during the past four and half years (July 2011 to December 2015). Information regarding the age, sex, gestational age, birth weight, clinical examination, x-rays value in diagnosis, causes and sites of perforations, types of operative procedures, and their effects on prognosis are all studied.Results: Males were affected more than females (a ratio of 3.4: 1); birth weight has a significant association with the prognosis (P-value of 0.045). Hirschsprung`s disease was the commonest cause for perforation (29%), followed by necrotizing enterocolitis and jejunoileal atresia (16.1%, each). Idiopathic perforations constituted only 12.9%. Ileum was the commonest site of perforation (58.1%), followed by cecum (16.1%). Stoma creation was the commonest operative procedure performed. Other procedures like, primary anastomosis, and primary peritoneal drainage followed by laparotomy were also used. This study revealed high mortality rate (45.2%). Complications like sepsis, anastomotic leaks, or burst abdomen carried a high risk of death.Conclusions: High mortality rate is encountered, especially for necrotizing enterocolitis. In contrast to other study, Hirschsprung`s disease is the commonest cause of perforation rather than necrotizing enterocolitis. Radiology has a relatively good accuracy in the diagnosis of intestinal perforations, although some cases were discovered intra-operatively. In this series, prompt accurate treatment with stoma creation harbored the best prognostic results; furthermore no benefits obtained from primary peritoneal drainage.
25
Devi, Parimala S., Ganesh Manikantan, and Meer M. Chisthi. "Gastrointestinal perforations: a tertiary care center experience." International Surgery Journal 4, no. 2 (2017): 709. http://dx.doi.org/10.18203/2349-2902.isj20170218.
Full textAbstract:
Background: In spite of the advances in surgical techniques and antimicrobial molecules, gastrointestinal perforations still remain highly fatal. Delay in diagnosis as well as referral is often attributed to be the cause behind the high mortality caused by this condition. The aim of the study was to elucidate the etiological factors of gastro intestinal perforation as well as postoperative outcome among patients undergoing treatment at a tertiary care centre.Methods: This was a Descriptive study of patients admitted with gastro intestinal perforation in the General Surgical wards of Government Medical College, Trivandrum from March 2014 to February 2015. The demographic, clinical, operative and post-operative findings were entered into a structured performa and analyzed statistically.Results: Atraumatic perforation was found to predominate over traumatic perforations. Most of the atraumatic perforations belong to the age groups between 21 and 30. Also, there is a high male predominance among these patients. Proximal gastrointestinal tract injuries predominate much more than distal ones. Increased morbidity is seen if there are associated co morbidities and risk factors including smoking and alcohol abuse. Mortality rate is highest in traumatic injuries involving colon and rectums.Conclusions: Mortality due to perforation peritonitis is still a challenge to the surgeon and burden to the society. Early diagnosis and treatment will positively alter the outcome of a gastrointestinal perforation and can be ensured only by timely arrival of the patients to hospital and subsequently by early intervention. This in turn depends mostly on strengthening the primary care and referral services.
26
Bakhshi, Girish D., Samprathi D., Akshat Mishra, and Mahesh Chanap. "Trans-duodenal migration of pancreatic duct stent into liver." International Surgery Journal 8, no. 5 (2021): 1640. http://dx.doi.org/10.18203/2349-2902.isj20211848.
Full textAbstract:
Endoscopic retrograde Cholangio-pancreatography (ERCP) is the one of the modalities for treating symptomatic pancreatic duct obstruction with dilation. A plastic stent placement is the standard technique followed. Complications after a plastic stent placement commonly found in the biliary tract in the form of migration into the duodenum with or without perforation have been widely described. Although complications of pancreatic duct stents are relatively rare, duodenal perforation secondary to pancreatic plastic stent migration into liver has not been described. Duodenal perforation results in perforative peritonitis when the intestinal contents leak into peritoneal cavity. However, stent migration resulting in duodenal perforation is a slow process where the inflammation results in adherence of surrounding organs, thereby preventing leak of intestinal contents into free peritoneal cavity. We present a case of contained duodenal perforation due to migration of pancreatic stent into liver. It is important to note that the chronic inflammatory process around the migrated pancreatic duct stent led to the asymptomatic nature patient in present case.
27
Kim, Soung Hee. "Entero-colonic Fistula Secondary to Necrotizing Enterocolitis in Premature Infant: A Case Report." Neonatal Medicine 30, no. 3 (2023): 83–87. http://dx.doi.org/10.5385/nm.2023.30.3.83.
Full textAbstract:
Necrotizing enterocolitis is a severe inflammatory disease of the intestine and is the main cause of death in infants, mostly occurring in premature infants. Intestinal obstruction may occur during the medical treatment of necrotizing enterocolitis. A common cause of intestinal obstruction is intestinal stricture, and entero-enteric fistulas may form in the proximal portion of the intestinal stricture. Several mechanisms may be suggested for the development of entero-enteric fistula. Intestinal ischemia and subsequent necrosis do not become intestinal perforation over time, causing an inflammatory reaction, and are attached to the adjacent intestine, forming a fistula. Alternatively, a subacute perforation may be sealed off by the adjacent intestine, resulting in fistula formation. Entero-enteric fistulas are closely related to distal stricture and occurs when there is a localized perforation rather than a generalized perforation. Fistulas can be diagnosed via contrast enema examination or distal loopogram, and surgical resection is required. Here, I report a case of a preterm infant with an entero-colonic fistula secondary to necrotizing enterocolitis. The patient had abdominal distention and bloody stool and was confirmed to have rotavius enteritis. Plain abdominal radiographs showed pneumatosis intestinalis. The patient received medical treatment for necrotizing enterocolitis. While the symptoms were improving, he vomited again, and intestinal obstruction was suspected. Gastrografin enema was performed due to intestinal obstruction, and an enterocolonic fistula was found.
28
Chanania, Rakesh Kumar, Lakshay Goyal, Sanjeev Gupta, Gagandeep Chanania, and Sahil Heer. "An Audit on Gastrointestinal Perforation in a Tertiary Care Teaching Hospital Based in Northern Part of India: A Study of 100 Cases." Annals of International Medical and Dental Research 8, no. 1 (2022): 106–16. http://dx.doi.org/10.53339/aimdr.2022.8.1.15.
Full textAbstract:
Background: A prospective study was conducted on 100 patients of perforation peritonitis: To find out the incidence of gastro intestinal perforation in various age groups, sex, riral or urban, socio economic status, To find out the various causes and sites of gastra intestinal perforartions, To determine various types of procedures being done to treat gastro intestinal perforations.Methods:The study population consisted of 100 patients of perforation peritonitis admitted at surgical wards of Rajindra Hospital, Patiala. Patients underwent necessary investigations such as Blood counts, biochemical analysis and urine analysis. X-ray Abdomen and chest / USG Abdomen/Pelvis CT-Abdomen (as and when required). All diagnosed patients were subjected to surgery. In all cases, operative findings and postoperative course were followed up for three months. Final outcome was evaluated on the basis of clinical, operative and radiological findings. In pre-pyloric and duodenal perforation, GRAHAM’S PATCH REPAIR carried out. In Ileal and Jejunal perforations, primary closure or exteriorization done depending upon the condition of the gut and duration of the symptoms. The patient outcome was assessed by duration of hospital stay, wound infection, wound dehiscence, leakage/entero-cutaneous fistula, intra-abdominal collection/abscess, ileostomy related complications and reoperation. Wound infection was graded as per SSI grading.Results:Most common age group for perforation was 21-40 years (50%) followed by 41-60 (33%) years in present study. Mean age of the patients is 37.91 + 13.15 years with male predominance (78%) in our study. 4% of the patients were of upper socio-economic status while 32% of the patients were of middle and 64% of the patients were of lower socio-economic status.Abdominal pain was seen in 100% of the patients while abdominal distension was present in 69% of the patients. Nausea/Vomiting was seen in 61% of the patients while Fever and Constipation was seen in 53% and 86% of the patients respectively. Diarrhoea was seen in 3% of the patients. Tenderness, guarding & rigidity, distension, obliteration of liver dullness and evidence of free fluid were present in 100% of the patients. Bowel sounds were not detected in all the patients. Most common perforations were Duodena(37%), Ileal (25%), Gastric (25%) followed by Appendicular (9%), Jejunal (4%) and Colonic perforation (2%). The most common etiology of gastrointestinal perforations was Peptic ulcer followed by Typhoid, Appendicitis, Tuberculosis, Trauma, Malignancy and non-specific infection.In Gastric perforations, Peptic ulcer was the most common cause of perforation followed by Trauma. In Ileal perforations, Typhoid was the most common cause of perforation followed by Tuberculosis and non-specific infection. In Appendicular perforations, most common cause was Appendicitis. In Jejunal perforations, most common cause was Trauma. In Colonic perforations, most common cause was Malignancy.Conclusions:The incidence of gastrointestinal perforations was common in 21-40 years age group followed by 41-60 years age group with male preponderance in our study. The most common site of perforations was Gastro-duodenal followed by Ileal perforations and the most common cause for these perforations was peptic ulcer followed by typhoid. The most common procedure done to treat gastrointestinal perforations was primary closure, resection and anastomosis, appendectomy and stoma formation. However, small sample size and short follow up period were the limitations of the present study.
29
CHEEMA, K. M., M. T. ASGHAR, and M. S. CHOUDHARY. "Role of Proximal Tube Enterostomy in the Management of Typhoid Enteric Perforation." Annals of King Edward Medical University 13, no. 1 (2021): 27–28. https://doi.org/10.21649/akemu.v13i1.4617.
Full textAbstract:
Typhoid perforation continues to have significant morbidity and mortality. A variety of surgical procedures like primary repair, wedge resection, intestinal resection, ileostomy and hemicolectomy reflect lack of consensus among surgeons. Complications like wound dehiscence, burst abdomen intra-abdominal abscesses and fecal fistula continue to be unacceptably high. Currently for solitary perforation primary repair is the most acceptable technique whereas for multiple perforations ileostomy is used. Tube enterostomy as an adjunct to primary repair in both solitary and multiple perforations is presented in an attempt to reduce above mentioned postop complications.
30
Patel, Azad, Paul Kelly, and Mulewa Mulenga. "Surgical Management of Typhoid Ileum Perforations: A Systematic Review." Medical Journal of Zambia 46, no. 4 (2019): 349–56. http://dx.doi.org/10.55320/mjz.46.4.610.
Full textAbstract:
Background: Typhoid is a disease caused by a gram negative bacterium Salmonella typhi. Prolonged infection leads to necrosis in the Peyer's patches of the antimesenteric border of bowel leading to intestinal perforation. Various surgical procedures have been described for the treatment of these perforations. Typhoid intestinal perforations are still associated with high case fatality rates averaging 15.4%.
 Objective: To identify current surgical management options for typhoid ileal perforations and to describe the best surgical management in relation to mortality and complications.
 Methods: A systematic review was done using PRISMA guidelines. Common search terms used were typhoid perforation/typhoid ileal perforation management. A narrative synthesis of the findings from the included studies structured around the type of intervention, target population characteristics, types of outcome and intervention content was done.
 Results: Primary closure of ileal perforations was the most commonly performed procedure.Ileostomy is the choice of surgery for severe abdominal contamination and when the patient has poor general health. Most studies found mortalities and complications to be unrelated to surgical procedure done. Mortality was significantlyassociated with the number of perforations and abdominal contamination.
 Conclusions: Individual studies support particular surgical interventions but the review showed that complications and mortality are not related to the type of surgical intervention alone but to a number of other non-surgical factors. There is need for further level 1 studies on this topic.
31
Patel, Azad, Paul Kelly, and Mulewa Mulenga. "Surgical Management of Typhoid Ileum Perforations: A Systematic Review." Medical Journal of Zambia 46, no. 4 (2020): 349–56. http://dx.doi.org/10.55320/mjz.46.4.245.
Full textAbstract:
Background: Typhoid is a disease caused by a gram negative bacterium Salmonella typhi. Prolonged infection leads to necrosis in the Peyer's patches of the antimesenteric border of bowel leading to intestinal perforation. Various surgical procedures have been described for the treatment of these perforations. Typhoid intestinal perforations are still associated with high case fatality rates averaging 15.4%.
 Objective: To identify current surgical management options for typhoid ileal perforations and to describe the best surgical management in relation to mortality and complications.
 Methods: A systematic review was done using PRISMA guidelines. Common search terms used were typhoid perforation/typhoid ileal perforation management. A narrative synthesis of the findings from the included studies structured around the type of intervention, target population characteristics, types of outcome and intervention content was done.
 Results: Primary closure of ileal perforations was the most commonly performed procedure.Ileostomy is the choice of surgery for severe abdominal contamination and when the patient has poor general health. Most studies found mortalities and complications to be unrelated to surgical procedure done. Mortality was significantlyassociated with the number of perforations and abdominal contamination.
 Conclusions: Individual studies support particular surgical interventions but the review showed that complications and mortality are not related to the type of surgical intervention alone but to a number of other non-surgical factors. There is need for further level 1 studies on this topic.
32
Misra, Tarun, Eoin Lalor, and Richard N. Fedorak. "Endoscopic Perforation Rates at a Canadian University Teaching Hospital." Canadian Journal of Gastroenterology 18, no. 4 (2004): 221–26. http://dx.doi.org/10.1155/2004/505970.
Full textAbstract:
BACKGROUND:Despite advances in training, operative techniques and endoscopic technology, upper and lower endoscopic procedures continue to have potential for intestinal perforation. Perforation rates provided to patients at the time of consent have frequently been derived from historical cohorts and survey datasets.OBJECTIVE:This study examined the perforation rates of upper and lower endoscopic procedures at a major Canadian tertiary care centre.METHODS:Inpatient and outpatient gastroscopies and colonoscopies performed during a three year period were evaluated. Endoscopies with perforations occurring within 14 days of procedure were retrospectively isolated using the International Classification of Diseases -- 9th Revision code descriptions, then retrieved and hand searched to confirm a procedure-related perforation. Data were extracted to identify risk factors and patient outcomes.RESULTS:A total of 21,217 endoscopies (13,792 gastroscopies and 7425 colonoscopies) were reviewed. Of these, 359 were identified, isolated and hand searched for confirmation of a perforation event. Eighteen were found to have an endoscopy-associated perforation. Ten perforations occurred with colonoscopy (0.13%) (incidence, 1.3/1000 procedures), resulting in one death (0.013%) (incidence, 0.13/1000 procedures). Eight perforations occurred with gastroscopy (0.06%) (incidence, 0.6/1000 procedures), resulting in zero mortality. Of colonoscopy procedures the rate of perforation with diagnostic colonoscopy was 0.13% (incidence, 1.3/1000 procedures) and with therapeutic colonoscopy was 0.14% (incidence, 1.4/1000 procedures). Of gastroscopy procedures the rate with therapeutic gastroscopy was 0.15% (incidence, 1.5/1000 procedures). No perforations occurred with diagnostic gastroscopy.CONCLUSION:Gastroscopy and colonoscopy procedures, especially those with therapeutic maneuvers, continue to carry morbidity and mortality risks associated with perforation.
33
WARDHAN, H., A. N. GANGOPADHAYAY, and G. D. SINGHAL. "Intestinal perforation in children." Journal of Paediatrics and Child Health 25, no. 2 (1989): 99–100. http://dx.doi.org/10.1111/j.1440-1754.1989.tb01426.x.
Full text
34
Marques Álvarez, Lara, Raquel Rodríguez-García, Carmen Palomo Antequera, Dolores Escudero Augusto, and Ignacio González-Pinto. "Intestinal Perforation After Liposuction." Cirugía Española (English Edition) 97, no. 9 (2019): 536–38. http://dx.doi.org/10.1016/j.cireng.2019.10.001.
Full text
35
Lawal, Abdulwahab Oluwatomisin, JULIUS DARE, HAFSOH OLABINJO, ADEDIRE ADENUGA, BALOGUN OLAYINKA, and ISHAQ AREMU. "Postpartum Typhoid Intestinal Perforation." Medical Journal of Zambia 49, no. 2 (2022): 198–201. http://dx.doi.org/10.55320/mjz.49.2.1135.
Full textAbstract:
Background: Typhoid fever remains a highly contagious and multi-systemic infection caused by salmonellae typhi, and like other gastro-enteric infection, it poses a higher risk of morbidity and mortality during pregnancy as a result of the physiological changes associated with pregnancy as well as concerns of antibiotic safety in pregnancy. The occurrence of typhoid perforation in pregnancy may be easily confused for other causes of acute abdomen in pregnancy.
 We report the presentation, management and outcome of a 25 year old postpartum woman who presented with typhoid intestinal perforation in a resource limited environment. She had an emergency exploratory laparotomy and was managed post operatively in the ICU but clinically deteriorated and subsequently died on the third post-operative day secondary to multiple organ failure from severe sepsis.
 Typhoid perforation in pregnancy is a rare presentation, a high index of suspicion, and early intervention, would reduce the incidence of morbidity and mortality associated with this disease condition.
36
Julius, Dare, Abdulwahab Oluwatomisin Lawal, Olabinjo Hafeezoh, Balogun Olayinka, Aremu Ishaq, and Adenuga Adedire. "Postpartum Typhoid Intestinal Perforation." Medical Journal of Zambia 49, no. 2 (2022): 198–201. http://dx.doi.org/10.55320/mjz.49.2.14.
Full textAbstract:
Background: Typhoid fever remains a highly contagious and multi-systemic infection caused by salmonellae typhi, and like other gastro-enteric infection, it poses a higher risk of morbidity and mortality during pregnancy as a result of the physiological changes associated with pregnancy as well as concerns of antibiotic safety in pregnancy. The occurrence of typhoid perforation in pregnancy may be easily confused for other causes of acute abdomen in pregnancy.
 We report the presentation, management and outcome of a 25 year old postpartum woman who presented with typhoid intestinal perforation in a resource limited environment. She had an emergency exploratory laparotomy and was managed post operatively in the ICU but clinically deteriorated and subsequently died on the third post-operative day secondary to multiple organ failure from severe sepsis.
 Typhoid perforation in pregnancy is a rare presentation, a high index of suspicion, and early intervention, would reduce the incidence of morbidity and mortality associated with this disease condition.
37
Gavrilyuk, Vasiliy P., Dmitriy A. Severinov, and Anatoliy M. Ovcharenko. "Surgical Tactics in Perforations of Stomach and Small Intestine in Children (Literature Review)." I.P. Pavlov Russian Medical Biological Herald 31, no. 3 (2023): 489–500. http://dx.doi.org/10.17816/pavlovj111829.
Full textAbstract:
INTRODUCTION: Currently, the number of pediatric patients urgently hospitalized with different variants of gastrointestinal perforations complicated with peritonitis, remains high. In the given work, the variants of the surgical treatment depending on the location of the perforation defect (stomach, duodenum, small intestine) are presented, and the most common causes of such conditions encountered in clinical practice, are described (perforation of Meckels diverticulum, spontaneous perforation of small intestine and stomach in children with extremely low body mass, patients with EhlersDanlos syndrome).
 AIM: To determine the most relevant variants of surgical tactics in children with perforations of different parts of the gastrointestinal tract (in particular, stomach, small intestine) in conditions of peritonitis.
 MATERIALS AND METHODS: In the process of studying the literature, 142 scientific publications were analyzed on Google Academy, PubMed, eLIBRARY information resources, published from 2002 to 2022. With this, works describing intestinal perforation with the underlying necrotic enterocolitis, were excluded from the study, since this category of patients requires a separate discussion and description of approaches to treatment.
 CONCLUSION: According to the results of the analysis of scientific literature, variants of surgical tactics used in perforations of the gastric wall include (in the order from the most commonly used to the least common): laparotomy and suturing with excision of the edges of the defect; suturing in conditions of laparoscopy; atypical resection with the formation of a gastric tube on the probe; resection of stomach. In duodenal perforations, the following methods are used: rhomboid duodeno-duodenoanastomosis according to Kimura, intracorporeal suture with endovideosurgical access; laparotomy and suturing of the defect in extensive necrosis. In spontaneous perforation in the small intestine, resection of the part of the intestine is advisable anastomosis according to Santulli in combination with terminal ileostomy, simultaneous end-to-end anastomosis or application of intestinal stomas.
38
Pinzón-Molina, María Camila, Ivette Jimenez-Lafaurie, and Rafael Roberto Peña-Fernandez. "INTESTINAL DUPLICATION ASSOCIATED TO PERFORATION IN A PEDIATRIC PATIENT: CASE REPORT." Annals of Mediterranean Surgery 7, no. 1 (2024): 12–16. https://doi.org/10.22307/2603.8706.2024.01.003.
Full textAbstract:
Abstract Introduction: Intestinal duplication associated with perforation is rare in children. This malformation can present with non-specific symptoms or even asymptomatically, until it is found as an incidental finding on diagnostic images. Perforation of the duplicated segment occurs mainly in adults and requires emergency surgical intervention. Case presentation: A 10-year-old patient was referred for suspected acute appendicitis due to generalized abdominal pain, emetic episodes, and fever, with imaging findings of a thickened tubular loop with signs of perforation associated with intra-abdominal collection, for which she was taken to laparoscopic appendectomy. A communicating loop with contained perforation was evident in the distal ileum, which required resection and end-to-end anastomosis. The pathology report confirms the diagnosis of perforated intestinal duplication. Conclusion: Intestinal duplication is a rare pathology. In patients who present gastrointestinal symptoms with signs of an inflammatory response, it should be considered as a differential diagnosis since it may be associated with intestinal obstruction or perforation. Keywords: Gastrointestinal tract, intestinal perforation, congenital anomalies, cyst, surgical anastomosis
39
U. D., Manoranjan, Nikhil S., and Chandrashekar M. S. "Evaluation of intestinal injuries from blunt abdominal trauma." International Surgery Journal 4, no. 12 (2017): 3971. http://dx.doi.org/10.18203/2349-2902.isj20175394.
Full textAbstract:
Background: To Evaluate the cause, presentation, anatomical extent, diagnostic method, management and outcome of intestinal injuries from blunt abdominal injuries.Methods: The study included 40 patients who underwent laparotomy for intestinal injuries from blunt abdominal trauma over a period of 1 year. A retrospective study was conducted, and the patients were evaluated with respect to the cause, presentation, anatomical distribution, diagnostic methods, associated injuries, treatment and mortality.Results: 40 patients with 58 major injuries to the bowel and mesentery due to blunt abdominal trauma were reviewed. The male to female ratio was 9: 1 and the average age was 32.51 years. There were 38 injuries to the small intestine including 1 duodenal injury, 13 colonic injuries and 6 isolated injuries to the mesentery. Out of 29 patients with intestinal perforation, free peritoneal air was present on plain abdominal and chest radiography in 23 patients. The commonest injury was a perforation at the antimesenteric border of the small bowel. Treatment consisted of laparotomy followed by simple closure of the perforation, resection and anastomosis and repair followed by protective colostomy for colonic perforations. 3 (7.56%) deaths were recorded, while 6 (15%) patients developed major complications.Conclusions: Bowel and mesenteric injuries may be significant and require immediate surgery or may be nonsignificant and permit nonsurgical treatment. Although early recognition of intestinal injuries from blunt abdominal trauma is difficult only by clinical assessment, nevertheless important to establish the right diagnosis due to its high infective potential. Intestinal perforations are often found accompanying other severe intra-peritoneal injuries which probably, are the determining factors in morbidity and mortality hence the main emphasis lying on early detection of the injuries and reducing the time from admission to the surgery thus playing a role in the reduction of mortality and morbidity associated with intestinal injuries following blunt trauma abdomen.
40
Kevin Emeka, Chukwubuike. "Resolution of Free Air in the Peritoneal cavity after Laparotomy for Bowel Perforation in Children: How Long Does It Take?" Journal of Surgery and Postoperative Care 2, no. 1 (2023): 01–04. http://dx.doi.org/10.58489/2836-8657/006.
Full textAbstract:
Background: Preoperatively, the presence of free air in the peritoneal cavity (pneumoperitoneum) is indicative of a gastrointestinal perforation and laparotomy exposes the peritoneal cavity and bowel to atmospheric air. The aim of this study was to evaluate how long (in days) it takes for free air in the peritoneal cavity to disappear following laparotomy in children. Materials and Methods: This was a prospective study of children aged 15 years and younger who had laparotomy for bowel perforation at the pediatric surgery unit of a teaching hospital in Enugu, Nigeria. This study covered a 5-year period. The patients were followed up postoperatively to evaluate which day post op the free air in the peritoneal cavity resolves. Results: A total of 112 cases of perforated bowel had laparotomy during the study period. Amongst this number, 37 (33%) patients showed pneumoperitoneum on their preoperative radiographs and form the basis of this report. There was male predominance. Abdominal pain is a consistent symptom in all the patients. Majority of the patients had typhoid intestinal perforation with single ileal perforation and primary intestinal repair was the most performed procedure. Wound infection was the most common post-operative complication and the general outcome was fair. Overall, the mean time for the pneumoperitoneum to disappear was 5.5 days postoperatively. Conclusion: Bowel perforation results mostly from infective/inflammatory processes such as typhoid intestinal perforation. Laparotomy is required for the repair of these perforations and its takes an average of 5.5 days for the free peritoneal air to resolve.
41
Ma, Zhenhua, Wujie Chen, Ye Yang, et al. "Successful colonoscopic removal of a foreign body that caused sigmoid colon perforation: a case report." Journal of International Medical Research 49, no. 2 (2021): 030006052098282. http://dx.doi.org/10.1177/0300060520982828.
Full textAbstract:
Large bowel perforation is an acute abdominal emergency requiring rapid diagnosis for proper treatment. The high mortality rate associated with large bowel perforation underlines the importance of an accurate and timely diagnosis. Computed tomography is useful for diagnosis of ingested foreign bodies, and endoscopic repair using clips can be an effective treatment of colon perforations. We herein describe a 78-year-old man with sigmoid colon perforation caused by accidental swallowing of a jujube pit. The jujube pit had become stuck in the wall of the sigmoid colon and was successfully removed by colonoscopy, avoiding an aggressive surgery. As a result of developments in endoscopic techniques, endoscopic closure has become a feasible option for the management of intestinal perforation.
42
Saharan, Sandeep, Anju Poonia, Amit Kumar, Dinesh, Sachin, and Deepak Kumar Tiwari. "Surgical Management of Ileocaecocolic Intussusception and Intestinal Perforation in a Kitten." Archives of Current Research International 24, no. 9 (2024): 57–60. http://dx.doi.org/10.9734/acri/2024/v24i9869.
Full textAbstract:
Objectives: Intussusception is defined as prolapse or invagination of one portion of the intestinal tract into the lumen of an adjoining segment. Most common sites of intussusception are enterocolic, and ileocolic. Intussusception is more common in kittens less than one year of age, while rare in adults. Vomition, melena, dyschezia, dehydration, abdominal pain and emaciation are common clinical signs. Intussusception along with intestinal perforations is rarely planned to be repaired surgically. We aim to describe a surgical procedure designed specifically to correct ileocaecocolic intussusception and intestinal perforation in a kitten surgically.
43
Ronald Gomes, Richmond. "A Rare Case of Pneumoperitoneum in Pregnancy: Perforation of Tubercular ileal Ulcer." Obstetrics Gynecology and Reproductive Sciences 5, no. 8 (2021): 01–04. http://dx.doi.org/10.31579/2578-8965/086.
Full textAbstract:
The incidence of tuberculosis (TB) is rising worldwide, despite the efficacy of the BCG vaccination. Populations at greatest risk of contracting TB are migrant communities, as well as immunocompromised individuals. The diagnosis of intestinal tuberculosis can often present as a diagnostic conundrum, due to its nonspecific and varied presentation, often mimicking inflammatory bowel disease or malignancy. Free perforation is one of the most feared complications of the intestinal tuberculosis. The terminal ileum is the most common site of perforation, while the majority of (90%) perforations are solitary. We present a 25 year old 17 weeks primi presented with peritonitis with solitary perforation of terminal ileum with miscarriage of fetus and subsequent surgical wedge resection of ileum and ileo-ileal anastomosis. Histology revealed presence of Langerhan’s cell with caseating granulomatous inflammation. There was no radiological evidence of pulmonary tuberculosis. Patient was started on anti-tubercular therapy and responded well. This present case underscores the importance of biopsy specimens taken from the margins of patients with ileal perforation to avoid the misdiagnosis of such condition.
44
D., Dharamdev, Rupa Merlyn Mascarenhas, and Arun Kumar. "A clinical study of the spectrum of gastro intestinal perforation peritonitis in a tertiary care centre." International Surgery Journal 8, no. 5 (2021): 1486. http://dx.doi.org/10.18203/2349-2902.isj20211813.
Full textAbstract:
Background: Acute abdomen is one of the most common causes of emergencies which present to surgeon. Gastrointestinal perforation is third most common cause for emergency explorative laparotomy. Most of the time when patient presents to the tertiary centre, it is by clinical examination and investigation a diagnosis of perforation is established. The objective of the study was to evaluate causes, signs and symptoms, various modalities of management and possible complications which develop in gastrointestinal perforations.Methods: 50 patients with features of perforation were chosen using purposive sampling technique. Descriptive statistics was used for analysis. Detailed history was taken, physical examination and relevant investigations were done and correlated with intra operative and histopathology report wherever possible and followed up for complications.Results: Duodenal perforation was the most common cause of perforation accounting for 32 out of 50 cases. Surgical site infection was common complication accounting for 14 out of 50 cases.Conclusions: Surgery remains mainstay in all perforations.
45
Takayama, Yuji, Masaaki Saito, Kosuke Ichida, Yuta Muto, Akira Tanaka, and Toshiki Rikiyama. "Intestinal perforation secondary to intestinal Burkitt lymphoma." International Journal of Surgery Case Reports 79 (February 2021): 417–20. http://dx.doi.org/10.1016/j.ijscr.2021.01.085.
Full text
46
Prasai, Parikshit, Anjali Joshi, Santosh Poudel, Sarjan K.C., and Rabin Pahari. "Cecal Perforation Following Intraperitoneal Abscess after Anti-tubercular Therapy: A Case Report." Journal of Nepal Medical Association 61, no. 258 (2023): 175–78. http://dx.doi.org/10.31729/jnma.8042.
Full textAbstract:
Abdominal tuberculosis is defined as infection of gastrointestinal tract, peritoneum, abdominal solid organs, and/or abdominal lymphatics constituting approximately 12% of extra-pulmonary tuberculosis cases. Intestinal perforation is an acute presentation of abdominal tuberculosis. Intestinal perforation can occur before or at the beginning of anti-tubercular therapy. It is considered to be a paradoxical reaction if it occurs during or after treatment. Intestinal perforation is uncommon but serious and life-threatening as complication-mortality rate secondary to perforation are estimated to be >30%. We present a case of an 18-year-old female who developed cecal perforation following an intraperitoneal abscess after completion of anti-tubercular therapy for intestinal tuberculosis. She was a known case of intestinal tuberculosis. She had undergone pigtail catheterisation for an intraperitoneal abscess and completed 18 months of anti-tubercular therapy after which she developed cecal perforation. A paradoxical response was observed following the completion of anti-tubercular therapy. Early diagnosis and treatment reduce the complications and mortality rates of cecal perforation due to abdominal tuberculosis.
47
Grassi, R., A. Pinto, G. Rossi, and A. Rotondo. "Conventional plain-film radiology, ultrasonography and CT in jejuno-ileal perforation." Acta Radiologica 39, no. 1 (1998): 52–56. http://dx.doi.org/10.1080/02841859809172149.
Full textAbstract:
Purpose: to evaluate conventional radiography, US and CT in identifying jejuno-ileal perforation Material and Methods: We retrospectively reviewed the findings of conventional radiography, US and CT in 13 consecutive patients with surgically proven jejuno-ileal perforation Results: the site of perforation was the ileum in 10 cases and the jejunum in 3 cases. Free gas was identified in 6 cases (46%) while indirect findings of perforation were found in 7 (54%). the jejunal perforations were diagnosed by indirect findings in all 3 cases. the ileal perforations were diagnosed by direct findings in 6 cases and indirect findings in 4 cases Conclusion: Conventional radiology did not detect free gas in 7 (54%) of the 13 patients examined. in the absence of free gas, radiology showed indirect signs in all 7 patients, the most common being intraperitoneal free fluid in 5 (71%) of them. Jejunal perforations were more rare than ileal perforations and more difficult to identify by radiology. US was not useful for detecting free gas but it was useful for identifying intraperitoneal free fluid and intestinal paresis. Abdominal CT was useful when performed 6 h after the symptoms began
48
Freeman, Hugh J. "Spontaneous Free Perforation of the Small Intestine in Crohn’s Disease." Canadian Journal of Gastroenterology 16, no. 1 (2002): 23–27. http://dx.doi.org/10.1155/2002/284958.
Full textAbstract:
Spontaneous free perforation of the small intestine is a rare but often dramatic event in the clinical course of Crohn’s disease. Fifteen new cases of spontaneous free perforation of the small intestine - nine female patients and six male patients – were discovered in a series of 1000 consecutively evaluated patients with Crohn’s disease seen during a period spanning 20 years, for an estimated frequency of 1.5%. Spontaneous free perforation was the presenting clinical feature of Crohn’s disease in nine (60%) of the newly discovered cases. Most perforations were located in the ileum rather than in the jejunum, and there were no duodenal free perforations. One patient with extensive intestinal disease presented with concomitant free perforations of the jejunum and ileum, while a second patient had two free ileal perforations that developed independently, separated by about six years. No perforations were the result of a superimposed malignant process, ie, adenocarcinoma or lymphoma. There have been no mortalities, and the subsequent clinical course of these patients has been limited to a minority requiring corticosteroid or immunosuppressive medications, or further surgical resections.
49
Naresh Kumar Jatin, Purohit. "A Case of Sealed Off Gastro-Intestinal Perforation." International Journal of Science and Research (IJSR) 12, no. 3 (2023): 390–91. http://dx.doi.org/10.21275/sr23225220453.
Full text
50
Amatya, Bhawana, Paleswan Joshi Lakhey, and Prativa Pandey. "Perforation Peritonitis at High Altitude." Journal of Nepal Medical Association 56, no. 210 (2018): 625–28. http://dx.doi.org/10.31729/jnma.3488.
Full textAbstract:
Trekkers going to high altitude can suffer from several ailments both during and after their treks. Gastro-intestinal symptoms including nausea, vomiting, and abdominal pain are common in high altitude areas of Nepal due to acute mountain sickness or due to a gastro-intestinal illness. Occasionally, complications of common conditions manifest at high altitude and delay in diagnosis could be catastrophic for the patient presenting with these symptoms. We present two rare cases of duodenal and gastric perforations in trekkers who were evacuated from the Everest trekking region. Both of them had to undergo emergency laparotomy and repair of the perforation using modified Graham’s patch in the first case and distal gastrectomy that included the perforated site, followed by two-layer end-to-side gastrojejunostomy and two-layer side-to-side jejunostomy in the second case. Perforation peritonitis at high-altitude, though rare, can be life threatening. Timely evacuation from high altitude, proper diagnosis and prompt treatment are essential