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Journal articles on the topic 'Intoxication indices'

Author: Grafiati

Published: 28 May 2022

Last updated: 30 July 2025

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1

Radchenko, O. M., O. V. Fedyk, and R. R. Guta. "HEMATOLOGICAL INDIXES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANEMIA." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 19, no. 3 (2019): 71–74. http://dx.doi.org/10.31718/2077-1096.19.3.71.

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A retrospective analysis of 470 patients with chronic obstructive pulmonary disease and anemia was conducted in order to determine hematological indices. 17 markers of inflammation activity, endogenous intoxication, adaptation, nonspecific and immune reactivity were calculated during this analysis. It was established that the course of chronic obstructive pulmonary disease with anemia was accompanied by a more pronounced inflammation syndrome with a significant increase in stab and segmented neutrophilic granulocytes, an acceleration of the erythrocyte sedimentation rate, and significantly hig

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2

Lishnevska, Anastasiia, Mykola Chemych, Oksana Chemych, and Igor Chernetsky. "Immunoreactivity and intoxication syndrome in patients with chronic viral hepatitis c." Bangladesh Journal of Medical Science 22, no. 3 (2023): 508–14. http://dx.doi.org/10.3329/bjms.v22i3.65314.

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Method: Etiological, gender, age and laboratory characteristics of chronic viral hepatitis C (СVHC) were studied and analyzed. The distribution of patients depending on the virus genotype, the activity degree and the severity of liver fibrosis were found out. Indices of non-specific reactivity, endogenous intoxication and inflammation in the course of СVHC, their dependence on treatment were studied. Correlations between the values of non-specific reactivity, endogenous intoxication, inflammation and patients’ affiliation to the group of injecting drug users, the APRI score, the stage of liver

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3

Gutsulyuk, V., I. Savytskyi, S. Tsypoviaz, S. Znamerovskyi, and R. Zashchuk. "Study of the role of erythrocyte and leukocyte intoxication indexes in the pathogenesis of experimental peritonitis." Journal of Education, Health and Sport 12, no. 4 (2022): 341–46. http://dx.doi.org/10.12775/jehs.2022.12.04.029.

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The article presents the results of studying the role of erythrocyte and leukocyte indices of intoxication in the pathogenesis of experimental peritonitis. When studying the role of erythrocyte and leukocyte indices, a unidirectional trend of their change was revealed. An increase in the erythrocyte index of intoxication in the pathogenesis of experimental fecal peritonitis was established, most pronounced on the 10th day of the experiment (the level of EII increased by 107% compared to intact animals). The results of the study of the leukocyte intoxication index indicate a unidirectional tren

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4

Prokofieva, T. V., O. S. Polunina, E. A. Polunina, I. V. Sevostyanova, and P. N. Voronina. "Assessment of endogenous intoxication based on the study of medium and low molecular weight substances in patients with myocardial infarction against a background of chronic obstructive pulmonary disease." Meditsinskiy sovet = Medical Council, no. 17 (October 15, 2022): 106–15. http://dx.doi.org/10.21518/2079-701x-2022-16-17-106-115.

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Introduction. Frequent comorbidity of chronic obstructive pulmonary disease and myocardial infarction is due to the commonality of a number of etiopathogenetic links and the development of endogenous intoxication syndrome. The convincing markers of endogenous intoxication syndrome are medium and low molecular weight molecules including medium and low molecular weight substances and oligopeptides.Aim. To study the levels of medium and low molecular weight substances in patients with myocardial infarction against the background of chronic obstructive pulmonary disease.Materials and methods. 225

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5

Poryvaeva, A. P., N. A. Vereshchak, S. V. Malkov, A. S. Krasnoperov, and Pechura E.V. "Diagnostic value of integral indexes of intoxication to assess the risk of complications development in gastric and intestinal diseases of calves." E3S Web of Conferences 222 (2020): 02015. http://dx.doi.org/10.1051/e3sconf/202022202015.

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The assessment of the intoxication degree and the state of general organism resistance was carried by identifying “hematological indices” showing the connections between various cell classes of leukocyte formula. Comparison of integral indices of intoxication has recorded “slight degree of intoxication of the organism” in sick calves in 47.6% of cases. In the case of “moderate severity of organism intoxication”, the tension in the hemopoiesis system was recorded in 85.7% of cases, and the imbalance in the reactions of the cellular and humoral link of immunity – in 48.1% cases. For animals with

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6

Svitailo, V. S., and M. D. Chemych. "INTEGRATIVE INDICATORS OF ENDOGENOUS INTOXICATION, INFLAMMATORY ACTIVITY, AND SPECIFIC REACTIVITY IN PATIENTS WITH COVID-19." Інфекційні хвороби, no. 3 (October 11, 2024): 21–27. http://dx.doi.org/10.11603/1681-2727.2024.3.14873.

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The aim of the study is to identify changes in blood laboratory parameters, integrative indicators of endogenous intoxication, inflammation, and specific reactivity in patients with coronavirus disease. Patients and methods. The study included 77 patients with COVID-19, taking into account the inclusion and exclusion criteria. The comparison group consisted of 68 practically healthy people of the corresponding age. Laboratory blood tests were performed, on the basis of which integrative indicators of endogenous intoxication, inflammation and specific reactivity were calculated. Results. The da

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7

Kudaeva, Irina V., L. B. Masnavieva, O. V. Naumova, and O. A. Dyakovich. "A SYSTEMATIC ANALYSIS OF RELATIONSHIPS BETWEEN BIOCHEMICAL INDICES IN PERSONS EXPOSED TO MERCURY." Hygiene and sanitation 97, no. 10 (2018): 990–94. http://dx.doi.org/10.18821/0016-9900-2018-97-10-990-994.

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Introduction. Changes in biochemical indices characterizing the state of lipid peroxidation processes - antioxidant protection and lipid metabolism are observed during the occupational contact with mercury. These changes play a certain pathogenic role in the formation of disorders in the nervous system during mercury intoxication. In this regard, the aim was to study the relationship between biochemical indices at different stages of the development of mercury intoxication to justify approaches to therapeutic and preventive measures. Material and methods. A prospective cohort examination of pe

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8

Partsei, Khrystyna, Hanna Ersteniuk, Bohdana Valishkevych, and Halyna Tokaryk. "Erythrocyte indices under conditions of energy drink consumption in Ukraine." Tanzania Journal of Health Research 25, no. 3 (2024): 1150–62. https://doi.org/10.4314/thrb.v25i3.13.

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Background: The consumption of energy drinks, especially among young people, is constantly growing worldwide despite warnings about their safety. Therefore, determining the consequences of their impact on the human body and well-being is an actual issue. This work aimed to study the state of endogenous intoxication and the antioxidant system of erythrocytes in experimental animals that consumed energy drinks. Methods: The study was conducted on rats that consumed energy drinks for a month. Samples for analysis were taken on the 10th day after the end of the experiment. The biochemical methods

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9

Karlova, O. O., O. V. Kuzminska, T. I. Trunina, and V. V. Melnyk. "The endogenous intoxication in workers exposed to lead." Likarska sprava, no. 5-6 (September 30, 2017): 162–67. http://dx.doi.org/10.31640/ls-2017(5-6)29.

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The calculated indices such as leukocytic (LI), hematological (HI) and nuclear (NI) became the most commonly used in clinical practice to determine the endogenous intoxication. The aim of this study was to determine informativeness of the calculation methods for verification of the endogenous intoxication in workers depending on the content of lead in their blood. The calculated indices (nuclear, hematological and leukocyte) have been carried out in the blood of 146 workers exposure to lead, whose concentration in the air of the working area exceeded the maximum permissible concentration 1.4–1

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10

Rubtsov, R. V. "The impact of the comprehensive treatment of the pneumoconiosis combined with the chronic obstructive pulmonary disease on some intoxication indicators in ore mining and iron and steel industry workers." Environment & Health, no. 1 (98) (February 2021): 42–48. http://dx.doi.org/10.32402/dovkil2021.01.042.

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Objective:We studied the efficiency of the comprehensive treatment of ore mining and iron and steel industry workers having the pneumoconiosis combined with chronic obstructive pulmonary disease in terms of intoxication indicators as an assessment of measures aimed at treatment and prevention of this occupational pulmonary pathology. Results: It was established that conducted treatment in the patients, ore mining and iron and steel industry workers with the use of bronchodilator, mucoregulator, anti-inflammatory agent of a complex vitamin medication, as well as sessions of hyperbaric oxygenati

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11

Syrota, B. V. "Immuno-hematological indices of endogenous intoxication and cellular reactivity at acute intoxication diarrheal escherichiosis." Bukovinian Medical Herald 23, no. 1 (89) (2019): 74–80. http://dx.doi.org/10.24061/2413-0737.xxiii.1.89.2019.11.

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12

Dzhyvak, V. H., O. I. Khlibovska, and I. M. Klishch. "ROLE OF ENDOGENIC INTOXICATION IN MUSCLE INJURY IN EXPERIMENT." International Journal of Medicine and Medical Research 5, no. 2 (2020): 122–27. http://dx.doi.org/10.11603/ijmmr.2413-6077.2019.2.10310.

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Background. Endogenous intoxication is a multicomponent complex process due to the endogenous biological products or dysfunction of systemic natural detoxification.  Objective. The aim of the research was to study the dynamics of indices of endogenous intoxication in rats with traumatic muscle damage in the experiment. Methods. The experiment was performed on 45 non-linear white rats, which were modeled with traumatic muscle damage. The level of endogenous intoxication was assessed by the content of medium plasma molecules (MMM), leukocyte and erythrocytic index of intoxication (LI

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13

Korotaeva, K. S., E. G. Furman, and Olga N. Sumlivaya. "Integral leukocgram indices in children with coronavirus infection COVID-19." Perm Medical Journal 39, no. 1 (2022): 27–34. http://dx.doi.org/10.17816/pmj39127-34.

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Objective. To study the changes in hematological leukocyte indices among children with coronavirus infection COVID-19 in the dynamics of infectious process. Materials and methods. The work is based on the analysis of clinical and laboratory data from 91 pediatric patients with COVID-19. On the basis of a general blood test, the following hematological leukocyte indices were determined: the entropy degree of leukogram according to A.V. Gorelov et al.; leukocyte intoxication index according to V.K. Ostrovsky; nuclear endotoxicosis degree index according to G.D. Dashtayants; Harkavi adaptat

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14

Radsikhovskii, M., L. Goralskii, B. Borissevich, and O. Dyshkant. "Integral indexes of intoxication in caninae coronaviridae enteritis." Naukovij vìsnik veterinarnoï medicini, no. 2 (144) (December 24, 2018): 13–19. http://dx.doi.org/10.33245/2310-4902-2018-144-2-13-19.

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In this article to be spoken about indicators of action of coronaviridae on an organism of animals – qualitative and quan-titative characteristics of blood. These indicators change at many patological reactions and participate in ensuring nonspe-cific and specific resistance of an organism. With the help of the analysis of integral leukocyte indices based on the formula of blood reflecting the state of neurohumoral homeostasis and immunological reactivity of the organism, the violations were first discovered and established humoral and cellular links of the immune system, micro- and macrophage

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15

Matveeva, E. L., A. G. Gasanova, E. S. Spirkina, and A. M. Ermakov. "Analysis of leukocyte indices in patients with revision hip arhtroplasty." Genij Ortopedii 29, no. 2 (2023): 155–58. http://dx.doi.org/10.18019/1028-4427-2023-29-2-155-158.

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Introduction The widespread application of large joint arthroplasty is accompanied by an increase in the complications associated with periprosthetic infection. Currently, treating patients with infectious complications in the area of large joint arthroplasty remains a relevant issue. Purpose To determine the prognostic value of leukocyte indices in patients with revision hip arthroplasty. Materials and methods The study involved 88 patients with revision hip arthroplasty hospitalized at the Ilizarov National Medical Research Centre for Traumatology and Orthopedics. The patients were divided i

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16

Voronova, Kristina A., and Lyudmila V. Kletikova. "Dynamics of hematological parameters against the background of adsorbent drugs for dyspepsia in calves." Far Eastern Agrarian Herald 17, no. 4 (2023): 85–92. https://doi.org/10.22450/1999-6837-2023-17-4-85-92.

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The main problem of diseases of the digestive system on livestock farms is the low adaptive capacity of young animal body. Subsequently, a large percentage of dyspepsia incidence is revealed. Violations of technologies for raising young animals result in a sharp transition in feeding and provoke the appearance of nutritional dyspepsia. Changes can be observed not only in the clinical status of calves, but in the hematological profile. Specialists primarily analyze the results of a general blood test, which does not reflect an objective picture of the disease. It would be more correct to consid

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17

Fleryanovich, Maria S., and Irina O. Pohodenko-Chudakova. "Role of integral leukocyte intoxication indices in assessing the severity of maxillofacial furuncles." Bulletin of Contemporary Clinical Medicine 18, no. 3 (2025): 81–86. https://doi.org/10.20969/vskm.2025.18(3).81-86.

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Introduction. Despite the wide possibilities of integral intoxication indices, there is a deficit of evidence-based data in the specialized literature regarding their informativeness in patients with maxillofacial furuncles. Aim of the study was to conduct a comparative evaluation of integral intoxication indices based on the retrospective analysis of medical records of persons with maxillofacial furuncles and to identify the most informative of them for patients in this category. Materials and Methods. Retrospective analysis was performed on 92 medical records of inpatients (40 women and 52 m

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18

Boev, I. A., A. P. Godovalov, G. I. Shtraube, and G. I. Antakov. "Characteristic features of maxillofacial phlegmon morbidity with assessment of efficiency of detoxication therapy." Perm Medical Journal 36, no. 2 (2019): 29–35. http://dx.doi.org/10.17816/pmj36229-35.

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Aim. To study the characteristic features of long-term facial phlegmon morbidity in Perm Krai with assessment of the efficiency of infusion therapy using indices of endogenous intoxication expression. Materials and methods. Manifestations of epidemic process of facial phlegmons were studied on the basis of a detailed retrospective analysis of sickness rate among the inhabitants of Perm Krai for the period of 2011–2016. In group 1, all patients besides standard therapy, underwent infusion therapy, and in group 2 – standard therapy alone. Prior to and after the therapy, peripheral blood ce

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19

Protasova, Elena N. "The functional activity of the brain in patients with occupational chronic mercury intoxication against background of the treatment of insomnia disorders." Hygiene and sanitation 103, no. 9 (2024): 973–79. http://dx.doi.org/10.47470/0016-9900-2024-103-9-973-979.

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Introduction. In patients with chronic mercury intoxication, insomnia disorders are much more common than in the general population. Persistent emotional disorders in combination with severe sleep disturbances may contribute to the progression of cognitive dysfunction in patients in the late post-exposure period of chronic mercury intoxication. The purpose of the study was to analyze the trend in electroencephalography indices and study cognitive evoked potentials in patients with occupational chronic mercury intoxication to optimize the treatment of insomnia. Materials and methods. Two groups

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20

Egorova, V. I., and I. V. Volkova. "Dynamics of integral hematological indices of fish in chronic intoxication." Fisheries, no. 1 (February 26, 2025): 81–88. https://doi.org/10.36038/0131-6184-2024-1-81-88.

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Today, laboratory practice has a rich arsenal of methods for dynamic control over the course of pathological processes in the body of fish. Quantitative indicators of blood leukocytes and, especially, indicators of its leukocyte formula are important re-search methods in the diagnosis of a wide variety of pathological conditions. To objectively assess these results, a number of indicators have now been proposed that determine the course of pathological processes in the body, but these indicators are not used in real fisheries science and aquaculture.The purpose of our study was to study the dy

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21

Chemych, Oksana M., Mykola D. Chemych, Anna A. Olefir, and Oleh B. Berest. "CLINICAL FEATURES OF THE HIV INFECTION COURSE AND THE DEPENDENCE OF CHANGES IN LABORATORY PARAMETERS ON THE CLINICAL STAGE AND ON THE CD4 LYMPHOCYTES LEVEL." Wiadomości Lekarskie 74, no. 5 (2021): 1189–95. http://dx.doi.org/10.36740/wlek202105126.

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The aim: Is to determine the features of the HIV infection and changes in indicators of endogenous intoxication and immunoreactivity depending on the clinical stage and the level of CD4 lymphocytes. Materials and methods: 72 HIV-patients were examined. Comparison group included 40 healthy blood donors. Clinical and laboratory examination was performed. Indicators of endogenous intoxication, nonspecific reactivity and inflammatory activity were calculated. Results:Main opportunistic infections were: oropharyngeal candidiasis; tuberculosis of different localization, more often pulmonary tubercul

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22

P. S. Nazar, M. M. Levon, O. I. Osadcha, and O. O. Shevchenko. "Dynamics of changes in the indices of the level of endogenous intoxication in patients with alcoholic lesions of the liver." Bukovinian Medical Herald 17, no. 1 (65) (2013): 68–70. http://dx.doi.org/10.24061/2413-0737.xvii.1.65.2013.17.

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Changes of the indices of the level of endogenous intoxication in 122 patients with an alcoholic lesion of the liver have been studied. It has been established that a high level of endogenous intoxication is identified in these patients connected with a reduction of the concentration of endogenous albumin in the peripheral blood, due to an accumulation of molecules of medium mass, a decrease of the effective concentration of albumin and the toxin-binding ability of albumin.

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23

M. V. Dikal, I. V. Matsiopa, and O. H. Cherniuh. "The effect of melatonin on the catalase and the blood glutathione transferase activity of rats in case of intoxication with 2,4-dinitrophenol." Bukovinian Medical Herald 17, no. 2 (66) (2013): 46–47. http://dx.doi.org/10.24061/2413-0737.xvii.2.66.2013.61.

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Changes of the blood antioxidant enzymes have been inverstigated on albino nonlinear male rats with toxic poisoning by 2,4-dinitrophenol. It has been established that the catalase activity in the rat blood increased against a background of the intoxication. At the same time, the glutathione transferase activity under the conditions of 2,4-dinitrophenol intoxication decreased as compared with the control. The introduction of exogenous melatonin resulted in a correction of the blood indices under study, approximating them to the control values.

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Dychko, D. V. "Level of cellular resistance of the organism of futzal sportsmen who are in the v critical period of immune system formation." Scientific Journal of National Pedagogical Dragomanov University. Series 15. Scientific and pedagogical problems of physical culture (physical culture and sports), no. 5(192) (May 24, 2025): 78–81. https://doi.org/10.31392/udu-nc.series15.2025.05(192).16.

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The article is devoted to the study of the level of cellular resistance of the body of male futsal athletes at the age range of 13-14 years, who are in the V critical period of the formation of the immune system. Research methods: 30 boys at the age from 13 to 14 years participated in the study. Two study groups were created. The first group of the EG included 15 male futsal players who constantly train at the Futsal Academy in Uzhhorod (average age of athletes – futsal players 13.53±0.08 years), the second CG consisted of 15 practically healthy peers who do not play futsal professionally (ave

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25

Pavliak, A. Ya, and O. V. Pyptiuk. "Endotoxicosis indices as means of prognosis in surgical sepsis caused by purulent-necrotic complications of sugar diabetes." Modern medical technologies 41 part 2, no. 2 (2019): 49–52. http://dx.doi.org/10.34287/mmt.2(41).2019.25.

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Purpose of the study. to study how the consequences of surgical sepsis caused by purulent-necrotic complications of sugar diabetes depend on the dynamics of endotoxicosis indices in the course of treatment. Material and methods. The research included 30 patients with the symptoms correlating with the criteria for surgical sepsis caused by purulentnecrotic complications of sugar diabetes. The patients had their level of endotoxicosis measured and the severity of their condition evaluated according to the scale. Results. 26 patients were discharged from hospital due to their recovery, 4 patients

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Konovchuk, Viktor M., Sergiy V. Kushnir, Andriy V. Andrushchak, Iryna I. Iliuk, and Petro V. Moroz. "THE CONDITION OF VOLUMETRIC AND OSMOREGULATORY FUNCTION OF THE KIDNEYS IN TOXICEMIA OF PURULENT-SEPTIC GENESIS IN PATIENTS WITH DIABETES MELLITUS." Wiadomości Lekarskie 73, no. 4 (2020): 733–36. http://dx.doi.org/10.36740/wlek202004120.

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The aim of the study is to investigate the state of volumetric and osmoregulatory function of the kidneys in diabetes complicated by the syndrome of the endogenous intoxication of purulent-septic genesis. Materials and methods: The study group was consisted of patients with insulin-dependent diabetes mellitus with complicated syndrome of the endogenous intoxication of purulent-septic genesis (CSDI). Results: The starting indices of volumetric and osmoregulatory function of the kidneys in patients with INCs complicated by the endogenous intoxication of purulent-septic genesis (CEI GHG) syndrome

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Karpenko, L., I. Makhnin, Yu Berenev, and A. Bakhta. "Prognostic value of some leukocyte indices of intoxication and reactivity in fish under the action of physico-chemical stressors." Genetics and breeding of animals, no. 4 (January 5, 2023): 61–67. http://dx.doi.org/10.31043/2410-2733-2022-4-61-67.

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Purpose: determining the prognostic value of leukocyte indexes of intoxication and reactivity in fish under the action of some physicochemical stressors.Materials and methods. The object of the study was the lady of the roach of ordinary Rutilus Rutilus (L.). Control and experimental groups were formed taking into account the principle of analogues (n = 90). The average mass (PP) is 5.29 ± 1.0 g, length (TL) - 7.22 ± 0.39 cm, fish of the juvenile period of development (the sexual structure was not installed). The individuals were accumulated (10 days) and contained the following indices in aqu

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Minigalieva, Ilzira A., Iuliya V. Ryabova, Marina P. Sutunkova, et al. "The combined action of lead and physical load in a subchorionic experiment on rats." Hygiene and sanitation 100, no. 12 (2021): 1404–11. http://dx.doi.org/10.47470/0016-9900-2021-100-12-1404-1411.

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Introduction. Exposure to lead associated with working conditions (especially in mining and metallurgical production) is usually combined with muscular work. However, the influence of this combination on the pathological process development has not been thoroughly studied. Materials and methods. During six weeks, white outbred male rats received intraperitoneal lead acetate at a dose of 11 mg / kg, corresponding to 1/20 LD50, three times a week and/or five times a week physical exercises (forced running for 10 minutes at a speed of 25 m/min). Results. As can be seen from the results, lead caus

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Ходус, Сергей, Sergey Hodus, Константин Пустовит, Konstantin Pustovit, Сергей Аникин, and Sergey Anikin. "METHOD FOR ASSESSING OF SEVERITY OF SYMPTOMS OF THE ENDOGENOUS INTOXICATION SYNDROME AND ASSOCIATED RESPIRATORY DISORDERS IN PATIENTS WITH COLORECTAL CANCER." Bulletin physiology and pathology of respiration 1, no. 69 (2018): 82–87. http://dx.doi.org/10.12737/article_5b985459376cf6.40782134.

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The purpose of the research is to develop a method for assessing the severity of symptoms of the endogenous intoxication syndrome and associated respiratory disorders in patients with colorectal cancer. The study involved 86 patients (the main group included 51 patients with colorectal cancer, the control group 35 relatively healthy people). All patients were studied upon indicators of clinical blood test, and hematological indices of intoxication were calculated. In the patients of the main group, an assessment of the oxygen status parameters was done. The study revealed that 52.9% of patient

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PROKOFYEVA, TATIANA V., OLGA S. POLUNINA, and EKATERINA A. POLUNINA. "PROGNOSIS OF SIGNIFICANT ISCHEMIC EVENTS AND LETHAL OUTCOME IN PATIENTS WITH MYOCARDIAL INFARCTION WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE." Bulletin of Contemporary Clinical Medicine 16, no. 2 (2023): 49–55. http://dx.doi.org/10.20969/vskm.2023.16(2).49-55.

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Introduction. Myocardial infarction remains significant due to its high prevalence and disability. Of particular importance is the prediction of the risk of adverse events in myocardial infarction patients with cardiorespiratory comorbidity, in particular with chronic obstructive pulmonary disease. It can be assumed that endogenous intoxication syndrome can be considered as a predictor of life-threatening events (repeated myocardial infarction, stroke) and lethal outcome in patients with myocardial infarction against chronic obstructive pulmonary disease. Aim. The aim is to determine the proba

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31

Duzhyi, I. D., O. L. Sytnik, V. Ya Pak, and I. M. Medvedieva. "Efficacy of lymphotropic parenteral antibacterial therapy in patients with an acute pancreatitis." Ukrainian Journal of Clinical Surgery 90, no. 1 (2023): 13–16. http://dx.doi.org/10.26779/2786-832x.2023.1.13.

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Objective.To compare clinical results of application of lymphotropic antibacterial therapy (LATH) versus standard method of parenteral administration of antibiotics in patients, suffering an acute pancreatitis. Materials and methods. Clinical data, the values of the leucocyte and hematological intoxication indices, and some other indices of immunity, occurring on background of lymphotropic and standard antibacterial therapy, were studied. The patients were distributed into two groups: Group I (the main) - to whom lymphotropic antibioticotherapy was conducted, and Group II (a control one)

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Kozitsyna, A. I., L. Yu Karpenko, and A. A. Bakhta. "Leukocyte indices in dogs with acquired primary hypothyroidism." Russian Journal of Immunology 27, no. 3 (2024): 477–82. http://dx.doi.org/10.46235/1028-7221-16747-lii.

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According to global statistics, hypothyroidism in dogs is a widespread disease. However, due to certain difficulties in conducting laboratory diagnostics, as well as the cross-species specificity of such indicators as thyroid-stimulating hormone, thyroglobulin autoantibodies, prompt diagnosis and differentiation of hypothyroidism in dogs in the practice of a veterinarian is difficult. Thus, it is relevant to search for secondary auxiliary methods of diagnosis and detection of hypothyroidism in dogs based on a set of indicators and diagnostic coefficients-indices. Since hypothyroidism causes an

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33

Dei, A. A., B. I. Geltser, M. V. Antonyuk, T. A. Gvozdenko, E. P. Kalinina, and I. N. Titorenco. "Assessing the relationship of respiratory muscle strength and cytokine status in patients with community-acquired pneumonia." PULMONOLOGIYA 31, no. 3 (2021): 311–19. http://dx.doi.org/10.18093/0869-0189-2021-31-3-311-319.

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Aim. Assessment of the role of cytokine-mediated changes in the development of respiratory muscle (RM) dysfunction in patients with community-acquired pneumonia (СAP). Methods. 84 men aged 18 – 26 years with a median of age 19.5 [18.4; 22.8]. Mild to moderate CAP (MCAP) was diagnosed in 62 (73.8%) patients and severe (SCAP) in 22 (26.2%). The expiratory (MEP, MRPDout) and inspiratory (MIP, MRPDin. SNIP) strength indices of RM were recorded on a MicrоRPM apparatus (CareFusion, UK). The severity of endogenous intoxication was verified using the following indices: hematologic (HII), leukocyte (LI

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Własow, Teresa. "Selected indices of immunologic resistance in rainbow trout (Salmo gairdneri Rich.) during prolonged, subacute phenolic intoxication." Acta Ichthyologica et Piscatoria 15, no. 2 (1985): 203–11. http://dx.doi.org/10.3750/aip1985.15.2.10.

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Bakhritdinova, F., K. Narzikulova, and S. Mirrakhimova. "Effect of photodynamic doses of laser irradiation on endogenous intoxication indices." Oftalmologicheskii Zhurnal 56, no. 4 (2015): 35–37. http://dx.doi.org/10.31288/oftalmolzh201543537.

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Chemych, Oksana, Mykola Chemych, Nina Malysh, Oleh Berest, Oleksandr Suprun, and Diana Svyrydenko. "Epidemiological and laboratory features of acute enteric infections." Bangladesh Journal of Medical Science 20, no. 4 (2021): 748–55. http://dx.doi.org/10.3329/bjms.v20i4.54129.

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Background: This work describes etiological structure and statistics for causes of acute enteric infections and salmonellosis in modern conditions. Method: It was analyzed the common epidemiologic signs and indices of modern acute enteric infections (AEI), caused by opportunistic microorganisms (OMO), various viruses and salmonella. Result: The research also shows the integrative intoxication indicators of causal groups in endogenous intoxication which point to these phenomena being caused by autointoxication at the moment of one’s own cells disruption as well as induced by bacteri

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Vlasov, A. P., D. Y. Timoshkin, M. A. Spirina, I. A. Chigakova, T. I. Vlasova, and T. A. Muratova. "LASER THERAPY FOR MANAGEMENT OF CEREBRAL DYSFUNCTION IN CASES OF ACUTE SEVERE PANCREATITIS." Russian Sklifosovsky Journal "Emergency Medical Care" 7, no. 2 (2018): 117–21. http://dx.doi.org/10.23934/2223-9022-2018-7-2-117-121.

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Background.A persistently high mortality rate of patients with pancreatitis is the result of multiple organ failure which is in many aspects associated with developing endogenous intoxication. Pancreatic encephalopathy is one of particular manifestations of this syndrome.Aim of study: to determine severity of cerebral dysfunction in cases of acute destructive pancreatitis, to assess the efficacy of laser therapy for this disease.Material and methods: The research is based on the results of clinical studies, carried out at the Republican Clinical Hospital No.3. Clinical laboratory analysis of 6

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Korobko, Y. Ye, V. S. Konoplitskyi, and O. O. Olkhomiak. "The value of a comprehensive assessment of the integrated indicator of endogenous intoxication of the organism and ultrasound imaging in the diagnostic process of the acute appendicitis in childhood." Paediatric Surgery. Ukraine, no. 4(73) (December 30, 2021): 59–65. http://dx.doi.org/10.15574/ps.2021.73.59.

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Traditionally, in the diagnosis of acute appendicitis and endogenous intoxication that accompanies its course, hemogram indicators and a wide range of proposed hematological indices are widely used. However, as practice shows, the isolated study of the hemogram, even with the involvement of its integral indices, especially in the early stages of pathology, is not enough for its timely diagnosis, and even more so the differential diagnosis. An important additional method of diagnosing acute appendicitis is ultrasound. Purpose – on the basis of specific clinical observation in the dynamics of th

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Krutikova, M., B. Cholah, V. Fedoseeva, A. Khrenov, N. Naumova, and A. Katsev. "PROTEINURIA AND ENDOGENOUS INTOXICATION IN PATIENTS WITH LIVER CIRRHOSIS." Tavricheskiy Mediko-Biologicheskiy Vestnik 23, no. 3 (2022): 61–66. http://dx.doi.org/10.29039/2070-8092-2020-23-3-61-66.

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In patients with liver cirrhosis, structural changes develop in the renal parenchyma, accompanied by a violation of the total renal function. These processes lead to the aggravation of endogenous intoxication and to the progression of the underlying disease. The aim of the study was to define the relationship between proteinuria and urine albumin/creatinine ratio with indicators of endogenous intoxication in patients with liver cirrhosis. 146 patients with liver cirrhosis with various etiologies were examined. In all patients, the presence of proteinuria, middle molecules level, creatini

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Гаглоева, Э. М., В. Б. Брин, С. В. Скупневский, Н. В. Боциева, and Т. В. Молдован. "EFFECTS OF NICKEL CHLORIDE ON INDICES OF HEMOCOAGULATION AND LIPID PEROXIDATION IN RATS." ZHurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia», no. 1() (March 11, 2019): 83–90. http://dx.doi.org/10.25557/0031-2991.2019.01.83-90.

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Цель исследования - изучить состояние системы гемостаза при хронической интоксикации хлоридом никеля, исследовать взаимосвязь показателей гемокоагуляции с процессами липопероксидации у крыс в эксперименте. Методика. Опыты проводили на крысах-самцах Вистар (n=50, 230-250 г). Раствор NiCl2 (5 мг/кг) вводили внутрижелудочно ежедневно в течение 2 нед, 1 и 2 мес. По завершении эксперимента исследовали состояние тромбоцитарного и коагуляционного звеньев гемостаза, антикоагулянтную и фибринолитическую активность крови, а также определяли активность процессов перекисного окисления липидов и антиоксида

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Anoshina, M. Yu, P. V. Yuschenko, V. I. Semenyaka, et al. "METABOLIC INTOXICATION EFFECT ON INDIVIDUAL TIME PERCEPTION INDEX IN PATIENTS WITH HEMOPHILIA." Health and Ecology Issues, no. 2S (December 28, 2011): 16–18. http://dx.doi.org/10.51523/2708-6011.2011-8-2s-1.

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The research results of the interrelation between the indices of metabolic intoxication and individual time perception (individual minute) in 112 patients with hemophilia with haemorrhages of various localization have been presented. It has been ascertained, that the indices of lipid peroxidation and permeability of erythrocytic membranes are criteria that make it possible to assess the ability of an organism for adaption. The index of individual time perception may serve as a marker for metabolism changes in hemophilia patients` organism, which allow of considering it as an additional assessm

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Prokofyeva, T. V., O. S. Polunina, L. P. Voronina, E. A. Polunina, and I. V. Sevostyanova. "Prognostic value of molecules of average mass in patients with chronic obstructive pulmonary disease." Acta Biomedica Scientifica 7, no. 6 (2022): 34–44. http://dx.doi.org/10.29413/abs.2022-7.6.4.

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Background. Chronic obstructive pulmonary disease is a socially significant disease affecting patient’s quality of life. Assessment of endogenous intoxication in patients with chronic obstructive pulmonary disease will allow to understand pathogenetic features of different phenotypes of this disease, which can be taken into account when predicting its course.The aim of the study. To determine the prognostic value of levels of mediumand low-molecular-weight substances and oligopeptides in patients with chronic obstructive pulmonary disease.Materials and methods. One hundred and four patients wi

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Klinova, Svetlana V., Boris A. Katsnelson, Ilzira A. Minigalieva, et al. "Cardioinotropic Effects in Subchronic Intoxication of Rats with Lead and/or Cadmium Oxide Nanoparticles." International Journal of Molecular Sciences 22, no. 7 (2021): 3466. http://dx.doi.org/10.3390/ijms22073466.

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Subchronic intoxication was induced in outbred male rats by repeated intraperitoneal injections with lead oxide (PbO) and/or cadmium oxide (CdO) nanoparticles (NPs) 3 times a week during 6 weeks for the purpose of examining its effects on the contractile characteristics of isolated right ventricle trabeculae and papillary muscles in isometric and afterload contractions. Isolated and combined intoxication with these NPs was observed to reduce the mechanical work produced by both types of myocardial preparation. Using the in vitro motility assay, we showed that the sliding velocity of regulated

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Vialichko, I. M., S. V. Lelevich, V. V. Lelevich, E. M. Doroshenko, and V. Yu Smirnov. "Neurotransmitter changes in the rat brain under combined intoxication induced by alcohol and morphine." Biomeditsinskaya Khimiya 67, no. 4 (2021): 323–30. http://dx.doi.org/10.18097/pbmc20216704323.

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We investigated the levels of biogenic monoamines and their metabolites in the rat hypothalamus, midbrain and cerebellum in acute complex intoxication with morphine and alcohol. The distinctive features of neurotransmitter disorders in various parts of the rat brain under a single exposure to ethanol and morphine, as well as the differences between acute morphine-alcohol and alcohol-morphine intoxication were established. Complex intoxication with alcohol and morphine resulted in signs of dopamine consumption only in the hypothalamus, regardless of the order of alcohol and morphine administrat

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Todoriko, L. D., Ya I. Toderika, O. S. Shevchenko, and M. G. Gingulyak. "Clinical and immunological characteristics of vitamin D level in drug-resistant tuberculosis." Infusion & Chemotherapy, no. 1 (March 23, 2025): 7–12. https://doi.org/10.32902/2663-0338-2025-1-7-12.

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BACKGROUND. To date, there are not enough studies that prove the relationship between a decrease in the level of vitamin D and the formation of resistance of mycobacterium tuberculosis. OBJECTIVE. Determination of vitamin D level in drug-resistant pulmonary tuberculosis and evaluation of its influence on the clinical course of the disease. MATERIALS AND METHODS. The randomized case-control study included 45 patients with newly diagnosed pulmonary tuberculosis with preserved sensitivity (group 1), 41 patients with multidrug-resistant tuberculosis (group 2) and 30 practically healthy individuals

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Суржиков, Дмитрий, Dmitry Surzhikov, Вера Кислицына, et al. "ASSESSMENT OF THE ENVIRONMENTAL RISK RELATED TO EMISSIONS INTO THE ATMOSPHERE PRODUCED BY THE KUZNETSK PLANT OF LIGHTWEIGHT STRUCTURES." Bulletin of Kemerovo State University. Series: Biological, Engineering and Earth Sciences 2017, no. 2 (2017): 74–77. http://dx.doi.org/10.21603/2542-2448-2017-2-74-77.

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The article presents the results of a risk assessment for the health of the Novokuznetsk residents from air emissions produced by the Kuznetsk plant of lightweight structures. The research has revealed substances that have the largest percentage in the total emissions of the enterprise. Among non-carcinogenic substances, the main pollutants included suspended substances, as well as dimethylbenzene (xylene), iron trioxide, white spirit and kerosene. The main carcinogenic substance contained in the emissions of the enterprise is chromium hexavalent. The highest indices of non-carcinogenic hazard

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Khokhlova, N. I., N. P. Tolokonskaya, and A. B. Pupyshev. "Multifactor clinical-laboratory valuation of endogenic intoxication in chronic hepatitis B." Bulletin of Siberian Medicine 10, no. 3 (2011): 139–44. http://dx.doi.org/10.20538/1682-0363-2011-3-139-144.

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For the determining of the role of clinical data and integral laboratory indices in the valuation of endogenic intoxication (EI) in chronic hepatitis B (HHB) 100 patients and 20 healthy adults were examined. The present symptoms of the disease and the facts about the character and communication of somatic diseases were studied and the effective concentration of albumin (ECA) and the reserve of albumin binding (RAB) were defined by fluorescence method twice at 18—20 days interval. The lowering of average indices of ECA and RAB was revealed in HHB patients in comparison with control group (p &lt

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Vlasova, Natal'ya V., Elena R. Abdrakhmanova, Lyalya M. Masyagutova, Alina R. Muzafarova, and Linara A. Rafikova. "Occupational conditionality of integral hematological indices in metallurgical production workers." Russian Journal of Occupational Health and Industrial Ecology 64, no. 1 (2024): 42–49. http://dx.doi.org/10.31089/1026-9428-2024-64-1-42-49.

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The health of the working population is one of the main guarantors of the sustainable and planned development of the state's economy, while working conditions and factors of the production environment play an important role in its formation. Studies of indicators of endogenous intoxication make it possible to identify the formation of adaptive and compensatory changes in the hemogram depending on the conditions of the production environment and the labor  process. The study aims to explore the degree of professional conditionality of integral hematological indices for early diagnos

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Geltser, B. I., A. A. Dej, I. N. Titorenko, and V. N. Kotelnikov. "Comparative analysis of the strength of the respiratory muscles in community-acquired pneumonia with different severity of endogenous intoxication." Terapevticheskii arkhiv 92, no. 3 (2020): 19–24. http://dx.doi.org/10.26442/00403660.2020.03.000372.

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Aim. To assess the strength of the respiratory muscles in patients with community-acquired pneumonia (CAP) with varying severity of endogenous intoxication. Materials and methods. In the hospital, 78 men aged 1826 years with CAP were examined. СAP was diagnosed in 56 (72%) patients, severe CAP in 22 (28%). The severity of endogenous intoxication was verified using intoxication indices: hematological index of intoxication (HII), leukocyte index of intoxication (LII), nuclear index of intoxication (NII) and Krebs index. Middleweight molecules (MWM) was determined by spectrophotometry in th

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Dychko, D. V. "The influence of the complex of physical activity on the level of cellular resistance of the organism in the process of training of futsal athletes." Scientific Journal of National Pedagogical Dragomanov University Series 15 Scientific and pedagogical problems of physical culture (physical culture and sports), no. 3(189) (March 26, 2025): 84–87. https://doi.org/10.31392/udu-nc.series15.2025.03(189).13.

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The article is devoted to the study of the influence of a complex of physical activity on the level of cellular resistance of the body during the training of futsal athletes at the age from 15 to 16 years and those who do not play futsal. Research methods: the study involved young futsal athletes of the Futsal Academy in Uzhorod, of the age range between 15-16 years (15.67±0.08 years), and a group of peers who do not play futsal (15.53±0.08 years). The level of cellular resistance was determined by the cellular resistance index, and preference was also given to the leukocyte intoxication index

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