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1

Haffaf, Idriss, Frédéric Clarençon, Eimad Shotar, et al. "Medina embolization device for the treatment of intracranial aneurysms: 18 months’ angiographic results." Journal of NeuroInterventional Surgery 11, no. 5 (2018): 516–22. http://dx.doi.org/10.1136/neurintsurg-2018-014110.

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Background and purposeThe Medina embolization device (MED) is a new flow disruption device combining the design of a detachable coil with an intrasaccular flow disrupter. Safety and short-term angiographic effectiveness of this device have recently been reported. However, long-term angiographic results are lacking. We report herein the 18 months’ angiographic outcome in patients treated for a wide-neck intracranial aneurysm with the MED.Materials and methodsNineteen patients (17 female, mean age 50 years) with 20 wide-neck intracranial aneurysms (six ruptured; 14 unruptured) were treated by th
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Behme, D., A. Berlis, and W. Weber. "Woven EndoBridge Intrasaccular Flow Disrupter for the Treatment of Ruptured and Unruptured Wide-Neck Cerebral Aneurysms: Report of 55 Cases." American Journal of Neuroradiology 36, no. 8 (2015): 1501–6. http://dx.doi.org/10.3174/ajnr.a4323.

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Pabón, Boris, Juan Andrés Mejía, Manuel Patiño, et al. "Abstract #7 WEB™ Aneurysm Embolization System Colombian Multicenter Experience (WEB.COM): Clinical and Angiographic Results in the Treatment of Intracranial Aneurysms Using an Intrasaccular Flow Disrupter." World Neurosurgery 158 (February 2022): 349. http://dx.doi.org/10.1016/j.wneu.2021.10.039.

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4

van Rooij, SBT, WJ van Rooij, M. Sluzewski, and JP Peluso. "The Woven EndoBridge (WEB) for recurrent aneurysms: Clinical and imaging results." Interventional Neuroradiology 25, no. 1 (2018): 21–26. http://dx.doi.org/10.1177/1591019918798806.

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Introduction The Woven EndoBridge (WEB) device is a novel intrasaccular flow disrupter designed for wide-necked aneurysms. We present our results of WEB treatment in previously treated and reopened aneurysms. Materials and methods Between February 2015 and December 2017, 17 patients with reopening of previously treated aneurysms were treated using the WEB device. Initial treatment was clipping in one, WEB in five and coiling in 11 aneurysms. Six aneurysms had two or three previous treatments. Mechanism of aneurysm reopening was clip remnant in one, compaction without regrowth in three, focal r
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5

Shao, Miriam M., Timothy G. White, Jared B. Bassett, et al. "Intrasaccular Treatment of Intracranial Aneurysms: A Comprehensive Review." Journal of Clinical Medicine 13, no. 20 (2024): 6162. http://dx.doi.org/10.3390/jcm13206162.

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Background: The endovascular treatment of complex intracranial aneurysms, such as wide-neck aneurysms (WNAs), remains a challenge. More established endovascular techniques, which include balloon-assisted coiling, stent-assisted coiling, and flow diversion, all have their drawbacks. Intrasaccular flow disruptor devices have emerged as a useful tool for the neurointerventionalist. Methods: Here, we discuss landmark studies and provide a comprehensive, narrative review of the Woven EndoBridge (WEB; Microvention, Alisa Viejo, CA, USA), Artisse (Medtronic, Irvine, CA, USA), Contour (Stryker, Kalama
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Papagiannaki, C., L. Spelle, A. C. Januel, et al. "WEB Intrasaccular Flow Disruptor—Prospective, Multicenter Experience in 83 Patients with 85 Aneurysms." American Journal of Neuroradiology 35, no. 11 (2014): 2106–11. http://dx.doi.org/10.3174/ajnr.a4028.

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7

Da Ros, Valerio, Alessio Bozzi, Chiara Comelli, et al. "Ruptured Intracranial Aneurysms Treated with Woven Endobridge Intrasaccular Flow Disruptor: A Multicenter Experience." World Neurosurgery 122 (February 2019): e498-e505. http://dx.doi.org/10.1016/j.wneu.2018.10.088.

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8

Caroff, J., C. Mihalea, J. Klisch, et al. "Single-Layer WEBs: Intrasaccular Flow Disrupters for Aneurysm Treatment—Feasibility Results from a European Study." American Journal of Neuroradiology 36, no. 10 (2015): 1942–46. http://dx.doi.org/10.3174/ajnr.a4369.

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9

Diana, Francesco, Marta de Dios de Dios Lascuevas, Simone Peschillo, et al. "Intrasaccular Flow Disruptor-Assisted Coiling of Intracranial Aneurysms Using the Novel Contour Neurovascular Systems and NEQSTENT: A Single-Center Safety and Feasibility Study." Brain Sciences 12, no. 8 (2022): 991. http://dx.doi.org/10.3390/brainsci12080991.

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Background: Intrasaccular flow disruptors (IFD) have been introduced in the treatment of intracranial aneurysms (IAs) to overcome the low aneurysm occlusion rate and the high recanalization rate of the coiling technique. Among them, the Contour Neurovascular System (CNS) and the Neqstent (NQS) were designed to reconstruct the aneurysmal neck and both can be used as assisting coiling devices. We aimed to report our preliminary experience with the flow disruptor-assisted coiling (IFD-AC) technique. Methods: We performed a retrospective analysis of prospectively collected data of all patients wit
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10

Gajera, Jay, Julian Maingard, Michelle Foo, et al. "The Woven EndoBridge Device for the Treatment of Intracranial Aneurysms: Initial Clinical Experience within an Australian Population." Neurointervention 17, no. 1 (2022): 28–36. http://dx.doi.org/10.5469/neuroint.2021.00430.

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Purpose: Advances in endovascular technology have expanded the treatment options for intracranial aneurysms. Intrasaccular flow diversion is a relatively new technique that aims to disrupt blood inflow at the neck of the aneurysm, hence promoting intrasaccular thrombosis. The Woven EndoBridge device (WEB; MicroVention, Aliso Viejo, CA, USA) is an US Food and Drug Administration approved intrasaccular flow diverter for wide-necked aneurysms. We report the early interim clinical and radiological outcomes of patients with both ruptured and unruptured intracranial aneurysms (IAs) treated using the
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11

Marotta, Thomas R., Howard A. Riina, Ian McDougall, Donald R. Ricci, and Monika Killer-Oberpfalzer. "Physiological remodeling of bifurcation aneurysms: preclinical results of the eCLIPs device." Journal of Neurosurgery 128, no. 2 (2018): 475–81. http://dx.doi.org/10.3171/2016.10.jns162024.

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OBJECTIVEIntracranial bifurcation aneurysms are complex lesions for which current therapy, including simple coiling, balloon- or stent-assisted coiling, coil retention, or intrasaccular devices, is inadequate. Thromboembolic complications due to a large burden of intraluminal metal, impedance of access to side branches, and a high recurrence rate, due largely to the unmitigated high-pressure flow into the aneurysm (water hammer effect), are among the limitations imposed by current therapy. The authors describe herein a novel device, eCLIPs, and its use in a preclinical laboratory study that su
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12

Heiferman, Daniel M., Jeremy C. Peterson, Kendrick D. Johnson, et al. "Woven EndoBridge Embolized Aneurysm Clippings: 2-Dimensional Operative Video." Operative Neurosurgery 21, no. 4 (2021): E365. http://dx.doi.org/10.1093/ons/opab218.

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Abstract The Woven EndoBridge (WEB) device (MicroVention, Aliso Viejo, California) is an intrasaccular flow disruptor used for the treatment of both unruptured and ruptured intracranial aneurysms. WEB has been shown to have 54% complete and 85% adequate aneurysm occlusion rates at 1-yr follow-up.1 Residual and recurrent ruptured aneurysms have been shown to have a higher risk of re-rupture than completely occluded aneurysms.2 With increased utilization of WEB in the United States, optimizing treatment strategies of residual aneurysms previously treated with the WEB device is essential, includi
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13

van Rooij, Sanne BT, Willem Jan van Rooij, Jo P. Peluso, and Menno Sluzewski. "The Woven EndoBridge (WEB) as primary treatment for unruptured intracranial aneurysms." Interventional Neuroradiology 24, no. 5 (2018): 475–81. http://dx.doi.org/10.1177/1591019918772174.

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Purpose The intrasaccular flow disruptor Woven EndoBridge (WEB) device is developed for the treatment of wide-necked aneurysms without supportive devices. We used the WEB as primary treatment for unruptured aneurysms suitable for the device, regardless of neck size. Methods Between February 2015 and June 2017, 59 aneurysms in 51 patients were selectively treated with the WEB. There were 15 men and 36 women with a mean age of 59 years. Mean aneurysm size was 7.0 mm (range 3–22 mm). Of 59 aneurysms, 45 (76%) had a wide neck defined as ≥4 mm or dome-neck ratio ≤1.5. No stents or supporting balloo
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14

Khattar, Nicolas K., Ahmad Alhourani, Sean Himel, et al. "122 Measured Aneurysm Entry Angle is an Independent Predictor of Aneurysm Occlusion with the Woven Endobridge Device." Neurosurgery 71, Supplement_1 (2025): 23–24. https://doi.org/10.1227/neu.0000000000003360_122.

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INTRODUCTION: Woven Endobridge (WEB) is a safe and effective intrasaccular flow disruptor with over 80% adequate occlusion rates. However, complete occlusion rates remain around 50-60%. Recent studies showed that sizing modifications and lateral compression correlate with occlusion rates. METHODS: This is a single center retrospective study of all cerebral aneurysms treated with WEB devices from August 2015 to December 2023 with follow-up data. We collected basic demographic, as well as follow-up data. The aneurysm entry angle was calculated by measuring the angle between the parent artery and
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15

Gutierrez‐Aguirre, Salvador F., Otavio F. De Toledo, Eduarda M. Freitas, et al. "Mediastinal Hematoma as a Potential Complication of Endovascular Intracranial Intervention." Stroke: Vascular and Interventional Neurology, October 6, 2024. http://dx.doi.org/10.1161/svin.124.001437.

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OBJECTIVE To highlight the rare incidence of mediastinal hematoma as a complication associated with transradial access, as reported in both cardiovascular and neurovascular fields. Interventionists must be aware of this potential risk and the strategies to manage it. CASE PRESENTATION A 66‐year‐old woman presented to an outside hospital's emergency department with 2 months of dizziness and vertigo. A right posterior communication artery aneurysm was discovered incidentally on workup images. On discussing potential options, including observation, the patient opted for endovascular intervention.
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Calienes, Aaron Rodriguez, Juan Vivanco‐Suarez, Milagros Galecio‐Castillo, et al. "Abstract 039: Angiographic Outcomes of Woven EndoBridge and Balloon‐Assisted Coiling for the Treatment of Ruptured Wide‐Necked Aneurysms." Stroke: Vascular and Interventional Neurology 3, S2 (2023). http://dx.doi.org/10.1161/svin.03.suppl_2.039.

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Introduction The optimal endovascular approach for wide‐neck intracranial aneurysms (IAs) during the acute phase of bleeding remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks (1, 2). Various techniques have been developed to address these challenges, including balloon‐assisted coiling (BAC) and intrasaccular flow‐disruption. The Woven EndoBridge (WEB) is a flow disrupter that has gained popularity in treating ruptured IAs due to its effectiveness in occluding aneurysms with minimal rebleeding
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17

Algin, Oktay. "Intrasaccular Flow Disruptor (Woven EndoBridge) Assisted Embolization of Vertebral Arteriovenous Fistulas." Neurointervention, February 16, 2024. http://dx.doi.org/10.5469/neuroint.2023.00514.

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18

Lane, Conor M., Waleed Brinjikji, Jason H. Anderson, and Rajiv Gulati. "Novel Treatment of Left Main Bifurcation Aneurysm With Intrasaccular Flow Disruptor." JACC: Cardiovascular Interventions, July 2025. https://doi.org/10.1016/j.jcin.2025.05.040.

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19

Bañez, Ramon Martin Francisco, and Winston Chong. "Retrieval of Displaced Woven EndoBridge Intrasaccular Flow Disruptor Using Solitaire Platinum Revascularization Device." Neurointervention, April 7, 2022. http://dx.doi.org/10.5469/neuroint.2022.00059.

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The Woven EndoBridge (WEB; MicroVention, Aliso Viejo, CA, USA) intrasaccular flow disruptor is a therapeutic option for wide neck bifurcation intracranial aneurysms that does not require the use of adjunctive techniques such as stents or balloon remodeling. As with other endovascular devices, displacement of the WEB is a recognized complication. Few reports have been published regarding the management of this type of complication. We describe a case of retrieval of a displaced WEB using a Solitaire Platinum revascularization device (Medtronic, Minneapolis, MN, USA). Interventionists should be
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Diestro, Jose Danilo Bengzon, Mahmoud Dibas, Nimer Adeeb, et al. "Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study." Journal of NeuroInterventional Surgery, July 22, 2022, neurintsurg—2022–019153. http://dx.doi.org/10.1136/jnis-2022-019153.

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BackgroundThe Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor tailored for bifurcation aneurysms. We aim to describe the degree of aneurysm occlusion at the latest follow-up, and the rate of complications of aneurysms treated with the WEB device stratified according to rupture status.MethodsOur data were taken from the WorldWideWeb Consortium, an international multicenter cohort including patients treated with the WEB device. Aneurysms were classified into two groups: ruptured and unruptured. We compared clinical and radiologic outcomes of both groups. Propensity score ma
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Zhou, Zibo, Wenjing Lan, and Jinlu Yu. "Endovascular treatment of middle cerebral artery aneurysms: current status and future prospects." Frontiers in Neurology 14 (November 15, 2023). http://dx.doi.org/10.3389/fneur.2023.1239199.

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Middle cerebral artery (MCA) aneurysms are complex and widely distributed throughout the course of the MCA. Various types of aneurysms can occur in the MCA. Ruptured as well as unruptured MCA aneurysms may require treatment to avoid bleeding or rebleeding. Currently, clipping is regarded as the first-line choice for the treatment of MCA aneurysms. However, endovascular treatment (EVT) is emerging as an alternative treatment in selected cases. EVT techniques vary. Therefore, it is necessary to review EVT for MCA aneurysms. In this review, the following issues were discussed: MCA anatomy and ano
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DeMessie, Bluyé, Dhrumil Vaishnav, Alireza Karandish, Muhammed Amir Essibayi, Nathan Farkas, and David J. Altschul. "Review of Endosaccular Flow Disrupters for Wide-Neck Aneurysm Treatment." Cardiology in Review, January 30, 2025. https://doi.org/10.1097/crd.0000000000000869.

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Endosaccular flow disruption has emerged as a transformative approach for treating wide-neck intracranial aneurysms, which are characterized by neck diameters exceeding 4 millimeters or dome-to-neck ratios below 2. This review examines the technical specifications and clinical outcomes of major endosaccular devices, including the Woven EndoBridge (WEB) device, the Artisse embolization device, the Medina embolization device, the neck bridging device for bifurcation aneurysms, the polycarbonate urethane membrane-assisted device, the Galaxy saccular endovascular aneurysm lattice, and the Contour
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Radomi, Alexandra, Lukas Goertz, Robert Forbrig, Muriel Pflaeging, Christoph Kabbasch, and Thomas Liebig. "Safety and efficacy of the Contour Neurovascular System for intracranial aneurysm treatment: a retrospective analysis of 76 patients." Journal of Neurosurgery, August 1, 2024, 1–9. http://dx.doi.org/10.3171/2024.5.jns232852.

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OBJECTIVE The Contour Neurovascular System (CNS) is a novel intrasaccular flow-disrupting device for the treatment of intracranial aneurysms. This study presents the authors’ institutional experience and midterm follow-up results with this device. METHODS Seventy-six consecutive patients (mean ± SD age 58.9 ± 12.4 years) were treated with the CNS for 76 aneurysms (63 unruptured, 10 recurrent, and 3 ruptured). Aneurysm characteristics, procedural details, and clinical/angiographic outcomes were retrospectively evaluated. RESULTS The most common aneurysm locations were the basilar tip in 25 (32.
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Saiegh, Fadi Al, David M. Hasan, Nikolaos Mouchtouris, et al. "Treatment of Acutely Ruptured Cerebral Aneurysms With the Woven EndoBridge (WEB) Flow Disruptor: A Multicenter Experience." Neurosurgery 66, Supplement_1 (2019). http://dx.doi.org/10.1093/neuros/nyz310_110.

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Abstract INTRODUCTION Coiling has become the first-line treatment option for acutely ruptured aneurysms 1 to 3. However, coiling of wide-necked bifurcation aneurysms is challenging and stent-assisted coiling requires dual anti-platelet therapy. The Woven EndoBridge (WEB) flow disruptor has been recently Food and Drug Administration (FDA)-approved for bifurcation aneurysms and is designed to achieve intrasaccular flow diversion without the need for antiplatelet therapy. However, its use has been mostly reserved for unruptured aneurysms. Here, we present our series of ruptured aneurysms that wer
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Yu, Jinlu. "Current research status and future of endovascular treatment for basilar artery aneurysms." Neuroradiology Journal, April 1, 2024. http://dx.doi.org/10.1177/19714009241242584.

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Aneurysms occurring along the basilar artery (BA) account for <1% of all intracranial aneurysms. Endovascular treatment (EVT) in particular is recommended for large unruptured BA aneurysms and ruptured BA aneurysms. Given that EVT techniques vary, a detailed review of EVT for BA aneurysms is necessary. In this review, the following issues were discussed: the anatomy and anomalies of the BA, the classification of BA aneurysms, the natural history of BA aneurysms, the status of open surgery, the use of EVT for various types of BA aneurysms and the deployment of new devices. According to the f
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Mihalea, Cristian, Felicia Otilia Humulescu, Hazem Abdelkhalek, Sorin Pescariu, Bogdan Valeriu Popa, and Horia Ples. "Initial single centre experience with Barrel VRD stent in large neck aneurisms." Romanian Neurosurgery, June 15, 2019, 127–34. http://dx.doi.org/10.33962/roneuro-2019-025.

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Introduction. Despite the use of new techniques, such as Y-stenting, the waffle-cone technique and intrasaccular flow disrupters the treatment of wide-neck bifurcation aneurysms is still challenging, especially for those where adjacent branches are arising at the neck level. Moreover, the use of flow diverter stents in bifurcation aneurysms has been proposed by several teams, although the results remain controversial.This study is reflecting initial experience in our department with a relatively new device available on the market: Barrel VRD stent. The unique design feature of the device is th
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Carraro do Nascimento, Vinicius, Laetitia de Villiers, Permesh Singh Dhillon, et al. "The Aristotle 18 and 24 microwires in neuroIntervention: Early experience at a single centre." Interventional Neuroradiology, October 5, 2023. http://dx.doi.org/10.1177/15910199231204923.

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Background Current neurointerventional procedures are expanding the use of large bore microcatheters, of up to 0.033” inner diameters, to accommodate intrasaccular flow disruptors or neck-bridging devices, including flow diverters. The use of large bore microwires may mitigate the ledge gap between wire and catheter, facilitate navigation and offer support in distal tortuous anatomy. We aim to report our early experience using the novel Aristotle (Scientia Vascular, West Valley City, UT) 18 and 24 microwires in neurovascular interventions. Methods We analysed neurointerventional procedures in
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Khatri, Deepak, Kainaat Javed, Mohamad Jalloh, Rose Fluss, Neil Haranhalli, and David Altschul. "Transcarotid access for the treatment of recurrent, previously ruptured wide necked bifurcation aneurysm with the WEB device: A technical video." Interventional Neuroradiology, September 16, 2022, 159101992211270. http://dx.doi.org/10.1177/15910199221127060.

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The Woven Endobridge (WEB) device is an FDA-approved intrasaccular flow disruptor to treat most intracranial wide-necked bifurcation aneurysms. 1 Based on the rising experience with safe and effective results, it has been increasingly utilized for the treatment of residual and recurrent aneurysms. 2 , 3 Additionally, the device has been reported as an off-label treatment option for Posterior communicating (Pcom) artery aneurysms with optimal morphology. 4 A transfemoral or transradial artery access is conventionally utilized for WEB embolization. 1 – 3 In this technical video, we share our exp
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Diestro, Jose Danilo Bengzon, Mahmoud Dibas, Nimer Adeeb, et al. "Stent-assisted Woven EndoBridge device for the treatment of intracranial aneurysms: an international multicenter study." Journal of Neurosurgery, October 1, 2023, 1–9. http://dx.doi.org/10.3171/2023.8.jns235.

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OBJECTIVE The Woven EndoBridge (WEB) device is an intrasaccular flow disruptor designed for wide-necked bifurcation aneurysms. These aneurysms may require the use of a concomitant stent. The objective of this study was to determine the clinical and radiological outcomes of patients undergoing stent-assisted WEB treatment. In addition, the authors also sought to determine the predictors of a concomitant stent in aneurysms treated with the WEB device. METHODS The data for this study were taken from the WorldWideWEB Consortium, an international multicenter cohort including patients treated with t
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Gaudino, Chiara, Stefania Elena Navone, Valerio Da Ros, et al. "Incidence of intra-procedural complications according to the timing of endovascular treatment in ruptured intracranial aneurysms." Frontiers in Neurology 13 (January 11, 2023). http://dx.doi.org/10.3389/fneur.2022.1096651.

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BackgroundAlthough endovascular treatment of ruptured intracranial aneurysms is well-established, some critical issues have not yet been clarified, such as the effects of timing on safety and effectiveness of the procedure. The aim of our study was to analyze the incidence of intra-procedural complications according to the timing of treatment, as they can affect morbidity and mortality.Materials and methodsWe retrospectively analyzed all patients who underwent endovascular treatment for ruptured intracranial aneurysms at three high flow center. For all patients, imaging and clinical data, aneu
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Adeeb, Nimer, Basel Musmar, Hamza Adel Salim, et al. "Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization." Journal of Neurosurgery, October 1, 2024, 1–11. http://dx.doi.org/10.3171/2024.5.jns232204.

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OBJECTIVE The Woven EndoBridge (WEB) device was approved to treat wide-necked bifurcation aneurysms. The device is designed as an intrasaccular flow disruptor covering aneurysm widths up to 10 mm. Although prior studies combined all aneurysm sizes, it is known that aneurysms behave differently in response to endovascular treatment based on their size. Therefore, the authors’ objective was to identify ideal middle cerebral artery (MCA) aneurysm width and neck sizes most suitable for WEB treatment. METHODS The WorldWideWEB consortium is a large multicenter retrospective database that analyzes in
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Kashkoush, Ahmed, Mohamed E. El-Abtah, Shaarada Srivatsa, et al. "Comparative effectiveness of stent-assisted coiling and Woven EndoBridge embolization for the treatment of unruptured wide-neck bifurcation intracranial aneurysms." Journal of Neurosurgery, November 1, 2022, 1–7. http://dx.doi.org/10.3171/2022.10.jns221138.

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OBJECTIVE Woven EndoBridge (WEB) intrasaccular flow disruptors and stent-assisted coiling (SAC) are viable endovascular treatment options for wide-neck bifurcation intracranial aneurysms (WNBAs). Data directly comparing these two treatment options are limited. The authors aimed to compare radiographic occlusion rates and complication profiles between patients who received WEB and those who received SAC for WNBAs. METHODS Retrospective review of a prospectively maintained cerebrovascular procedural database was performed at a single academic medical center between 2017 and 2021. Patients were i
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Padmanaban, Varun, Junjia Zhu, Shouhao Zhou, et al. "Safety and efficacy of endovascular versus microsurgical treatment of unruptured wide-necked middle cerebral artery aneurysms: a propensity score–matched analysis of the NeuroVascular Quality Initiative Quality Outcomes Database Cerebral Aneurysm Registry." Journal of Neurosurgery, December 1, 2023, 1–9. http://dx.doi.org/10.3171/2023.10.jns231659.

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OBJECTIVE Unruptured, wide-necked middle cerebral artery (WN-MCA) aneurysms have traditionally been considered ideal candidates for microsurgery (MS), although endovascular treatment (EVT) has dramatically increased in popularity with the advent of novel devices such as intrasaccular flow disruptors. The purpose of this study was to evaluate the safety and efficacy of MS versus EVT for unruptured WN-MCA aneurysms. METHODS The NeuroVascular Quality Initiative Quality Outcomes Database (NVQI-QOD) Cerebral Aneurysm Registry, a multiinstitutional, prospectively collected procedural database, was q
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