Academic literature on the topic 'Intrathecal Pressure'

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Journal articles on the topic "Intrathecal Pressure"

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Riphagen, Colleen L., and Quentin J. Pittman. "Mechanisms underlying the cardiovascular responses to intrathecal vasopressin administration in rats." Canadian Journal of Physiology and Pharmacology 67, no. 4 (1989): 269–75. http://dx.doi.org/10.1139/y89-044.

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Vasopressinergic pathways within the spinal cord have been implicated in the control of cardiovascular function. This study was undertaken to determine the mechanisms whereby intrathecally administered arginine vasopressin (AVP) increases blood pressure and heart rate in anesthetized rats. The cardiovascular responses to intrathecal AVP administration were significantly attenuated after intravenous administration of the ganglionic blocking agent, chlorisondamine chloride, as were the pressor responses following α-adrenergic receptor blockade with phentolamine and the heart rate responses follo
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Sia, A. T. H., M. Y. H. Chow, C. K. Koay, and J. L. Chong. "Intrathecal Pethidine: An Alternative Anaesthetic for Transurethral Resection of Prostate?" Anaesthesia and Intensive Care 25, no. 6 (1997): 650–54. http://dx.doi.org/10.1177/0310057x9702500610.

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We aimed to determine the usefulness of intrathecal pethidine as the sole anaesthetic for transurethral resection of prostate (TURP) while comparing the incidence of hypotension with intrathecal bupivacaine. A double-binded randomized prospective trial was conducted involving 40 patients for TURP. The patients were divided equally into two groups; group A received 2 ml 0.5% bupivacaine intrathecally and group B received 40 mg pethidine intrathecally. Changes in blood pressure and heart rate were measured over the first 30 minutes. The highest sensory block and the time to reach it were documen
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Zada, Gabriel, and Thomas C. Chen. "A Novel Method for Administering Intrathecal Chemotherapy in Patients With Leptomeningeal Metastases and Shunted Hydrocephalus: Case Report." Operative Neurosurgery 67, no. 3 (2010): ons. http://dx.doi.org/10.1227/01.neu.0000383138.78632.ba.

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Abstract BACKGROUND AND IMPORTANCE: Leptomeningeal metastatic disease occurs in a minority of patients with systemic neoplastic disease. Before the initiation of intrathecal chemotherapy, hydrocephalus must be addressed with a cerebrospinal fluid (CSF)-diverting shunt. CSF diversion can theoretically prematurely divert chemotherapeutic drugs that are administered intrathecally, thereby potentially reducing the efficacy of such treatments. CLINICAL PRESENTATION: We report on a patient with leptomeningeal disease and hydrocephalus secondary to metastatic bladder carcinoma requiring insertion of
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Lohana, Abhi Chand, Sejal Neel, Vishal Deepak, and Mark Schauer. "Intrathecal iodinated contrast-induced transient spinal shock." BMJ Case Reports 13, no. 12 (2020): e237610. http://dx.doi.org/10.1136/bcr-2020-237610.

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Transient spinal shock is a previously unreported complication of intrathecal contrast. A 63-year-old man presented with the chief complaint of worsening back pain. Computed topography of lumbar spine without contrast showed a lytic lesion. After international normalized ratio (INR) correction, patient was sent for CT myelogram. After intrathecal contrast injection, the patient dropped his blood pressure profoundly and developed clinical manifestations of spinal shock. Emergent intravenous bolus fluids were initiated resulting in improvement in blood pressure. Patient’s spinal shock resolved w
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Sansur, Charles A., John D. Heiss, Hetty L. DeVroom, Eric Eskioglu, Robert Ennis, and Edward H. Oldfield. "Pathophysiology of headache associated with cough in patients with Chiari I malformation." Journal of Neurosurgery 98, no. 3 (2003): 453–58. http://dx.doi.org/10.3171/jns.2003.98.3.0453.

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Object. The aim of this study was to evaluate the pathophysiology underlying headache associated with cough in patients with Chiari I tonsillar abnormality. The authors hypothesized that peak intrathecal pressure during coughing is higher in patients with headache aggravated by cough than in patients without or in healthy volunteers. In addition, the authors evaluated the use of intrathecal pressure during cough as a means of assessing obstruction to the free flow of cerebrospinal fluid (CSF) at the craniocervical junction. Methods. Twenty-six adult patients with Chiari I malformation and syri
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Hayashida, Ken-ichiro, Renée Parker, and James C. Eisenach. "Oral Gabapentin Activates Spinal Cholinergic Circuits to Reduce Hypersensitivity after Peripheral Nerve Injury and Interacts Synergistically with Oral Donepezil." Anesthesiology 106, no. 6 (2007): 1213–19. http://dx.doi.org/10.1097/01.anes.0000267605.40258.98.

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Background Gabapentin administration into the brain of mice reduces nerve injury-induced hypersensitivity and is blocked by intrathecal atropine and enhanced by intrathecal neostigmine. The authors tested the relevance of these findings to oral therapy by examining the efficacy of oral gabapentin to reduce hypersensitivity after nerve injury in rats and its interaction with the clinically used cholinesterase inhibitor, donepezil. Methods Male rats with hypersensitivity after spinal nerve ligation received gabapentin orally, intrathecally, and intracerebroventricularly with or without intrathec
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Vaidyanathan, Subramanian, Tun Oo, Bakul M. Soni, Peter L. Hughes, and Gurpreet Singh. "Severe, Protracted Spasm of Urinary Bladder and Autonomic Dysreflexia Caused by Changing the Suprapubic Catheter in a Cervical Spinal Cord Injury Patient: Treatment by a Bolus Dose and Increased Total Daily Dose of Intrathecal Baclofen." Clinical Medicine Insights: Case Reports 9 (January 2016): CCRep.S39117. http://dx.doi.org/10.4137/ccrep.s39117.

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Background Intrathecal administration of baclofen by implanted pump reduces rigidity and muscle spasms. Its use specifically to control bladder spasms has not been reported. Case Report A tetraplegic patient developed severe, protracted, bladder spasms, abdominal muscles spasms, and high blood pressure after change of suprapubic catheter; nifedipine, diazepam, and paracetamol did not control spasms; bolus dose of baclofen intrathecally produced prompt relief via baclofen pump. Conclusion Severe, protracted bladder spasms, abdominal muscles spasms, and autonomic dysreflexia, induced by change o
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Eisenach, James C., Patricia Lavand'homme, Chuanyao Tong та ін. "Antinociceptive and Hemodynamic Effects of a Novel α2-Adrenergic Agonist, MPV-2426, in Sheep". Anesthesiology 91, № 5 (1999): 1425. http://dx.doi.org/10.1097/00000542-199911000-00036.

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Background alpha2-Adrenergic agonists produce analgesia primarily by a spinal action and hypotension and bradycardia by actions at several sites. Clonidine is approved for epidural use in the treatment of neuropathic pain, but its wider application is limited by hemodynamic side effects. This study determined the antinociceptive and hemodynamic effects of a novel alpha2-adrenergic agonist, MPV-2426, in sheep. Methods Forty sheep of mixed Western breeds with indwelling catheters were studied. In separate studies, antinociception to a mechanical stimulus, hemodynamic effects, arterial blood gas
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Porter, J. P., and M. J. Brody. "Spinal vasopressin mechanisms of cardiovascular regulation." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 251, no. 3 (1986): R510—R517. http://dx.doi.org/10.1152/ajpregu.1986.251.3.r510.

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Extrahypothalamic vasopressin-containing neurons have been implicated in the central neural control of the cardiovascular system. In the present study we investigated the possibility that vasopressinergic neurons arising from the paraventricular nucleus (PVN) and terminating in the spinal cord are involved in the regulation of vasomotor functions. Vasopressin (1-17 pmol) was injected into the spinal subarachnoid space of conscious rats instrumented with Doppler flow probes and indwelling intrathecal catheters. The peptide produced a dose-related increase in arterial pressure accompanied by vas
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Omote, Keiichi, Mikito Kawamata, Osamu Satoh, Hiroshi Iwasaki, and Akiyoshi Namiki. "Spinal Antinociceptive Action of an N-Type Voltage-dependent Calcium Channel Blocker and the Synergistic Interaction with Morphine." Anesthesiology 84, no. 3 (1996): 636–43. http://dx.doi.org/10.1097/00000542-199603000-00019.

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Background Four different voltage-dependent calcium channels (L-, N-, T-, and P-types) are distinguished in the central nervous system. Both L- and N-type calcium channels have been implicated in the release of neurotransmitters from sensory neurons in the spinal cord. It has been demonstrated that intrathecal L-type calcium channel blockers, which alone do not exhibit any antinociceptive effects, potentiate the antinociceptive effect of intrathecal morphine. The current study was designed to investigate the antinociceptive effects of the intrathecally administered N-type calcium channel block
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Books on the topic "Intrathecal Pressure"

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Candido, Kenneth D., Teresa M. Kusper, Bora Dinc, and Nebojsa Nick Knezevic. Epidural Blood Patch. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0036.

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Post-dural-puncture headache (PDPH) is a consequence of neuraxial anesthesia, diagnostic lumbar puncture, intrathecal drug delivery systems, or any other technique involving dural trespass. The spinal headache results from a dural puncture that leads to cerebrospinal fluid (CSF) leakage from the subarachnoid space to the epidural space, culminating in intracranial hypotension and development of a low-pressure headache. A key element of PDPH is an increase in pain severity upon a change in position from supine to upright, which corresponds to a gravity-induced influence on CSF pressure dynamics
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Flower, Oliver, and Raymond Raper. Ongoing management of the tetraplegic patient in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0345.

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This chapter focuses on the intensive care management of patients who have suffered cervical spinal cord injury (CSCI). This includes new CSCI, following initial resuscitation and stabilization, and the common issues faced when managing longstanding tetraplegic patients who require critical care. For patients with a new diagnosis of CSCI, a comprehensive systems-based approach is suggested covering topics including terminology, the standardized neurological examination, muscle spasticity, neuropathic pain, venous thromboembolism prophylaxis, as well as renal, gastrointestinal, and pressure car
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Paech, Michael J., and Patchareya Nivatpumin. Postdural puncture headache. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0027.

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Postdural puncture headache (PDPH) may follow either deliberate or unintentional (accidental) penetration of the interdigitating meninges, the dura and arachnoid mater. It is one of the most common and clinically important complications of regional anaesthesia and analgesia in the obstetric population. The headache develops as a consequence of cerebrospinal fluid loss, low intracranial pressure and cerebrovascular changes in the upright position and can prove debilitating. The diagnosis is clinical, making thorough assessment and regular review all the more important, to revise treatment plans
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Book chapters on the topic "Intrathecal Pressure"

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Kuklane, M., J. Eelmäe, M. Roose, and A. E. Kaasik. "Correction of CSF Acidosis and Craniospinal System Viscoelastic Parameters with Intrathecal THAM." In Intracranial Pressure VIII. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77789-9_135.

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Dhasmana, K. Mohan, Ajay K. Banerjee, and Pramod R. Saxena. "The effects of intrathecal ketanserin and phentolamine on heart rate and arterial blood pressure in the rat." In Cardiovascular Pharmacology of 5-Hydroxytryptamine. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0479-8_30.

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Tomlinson, Amanda D., and William D. Freeman. "Intracranial Pressure Monitoring and External Ventricular Drainage." In Mayo Clinic Critical and Neurocritical Care Board Review, 2nd ed., edited by Eelco F. M. Wijdicks, Rodrigo Cartin-Ceba, William D. Freeman, Alice Gallo de Moraes, and Richard A. Oeckler. Oxford University Press, 2025. https://doi.org/10.1093/med/9780197628638.003.0124.

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Abstract Intracranial pressure (ICP) can increase with added volume (eg, from a hemorrhage, tumor, or edema) in the fixed intracranial vault of an adult. ICP monitoring should be considered for all patients who are expected to recover after a severe traumatic brain injury, are comatose (with a nonlocalizing motor response) after resuscitation, and have acute abnormal findings with head computed tomography. External ventricular drain (EVD) placement often is performed to alleviate hemorrhagic hydrocephalus (eg, from intraventricular or subarachnoid hemorrhage), to monitor ICP, and to divert or drain trapped cerebrospinal fluid. EVD catheters may be used to instill intraventricular or intrathecal medications. ICP waveforms are a valuable tool for the bedside clinician because they enable assessment of trends in elastance or compliance that could identify the need for urgent interventions.
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Barker, Roger A., Wendy Phillips, and R. Rhys Davies. "Lumbar puncture." In Oxford Textbook of Medicine. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199204854.003.24301.

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Lumbar puncture provides the means to sample cerebrospinal fluid for diagnostic purposes and to remove it for some therapeutic purposes. The procedure allows measurement of the pressure of cerebrospinal fluid, its cytological composition, biochemical content, and microbial as well as serological characteristics. Indications—the commonest diagnostic indications are clinical suspicion of central nervous system infection (meningitis, encephalitis), subarachnoid haemorrhage, and demyelinating diseases (central and peripheral); the commonest therapeutic indications are idiopathic intracranial hypertension and for intrathecal administration of drugs....
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Holle, Dagny, and Julio Pascual. "Headache and Chiari malformation." In Oxford Textbook of Headache Syndromes, edited by Michel Ferrari, Joost Haan, Andrew Charles, David W. Dodick, Fumihiko Sakai, and Christopher Kennard. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198724322.003.0048.

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Chiari malformation is a rare medical condition that is characterized by downward displacement of the cerebellar tonsils through the foramen magnum. The clinical presentation of Chiari malformation is diverse, but headache is the most often reported symptom. The typical Chiari malformation headache is localized in the occipital part of the head and aggravated by coughing, other Valsalva manoeuvres, or physical exertion. The prevalence of other episodic primary headache disorders such as tension-type headache and migraine is not increased in patients with Chiari malformation. The underlying pathophysiology of headache in Chiari malformation is still enigmatic, but alteration of intrathecal pressure was suggested to be involved. Controlled treatment trials for CM-related headaches are not available and treatment recommendations are mainly based on case reports, small case series and clinical experience. Therefore, no firm recommendation regarding surgical treatment can be made.
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Conference papers on the topic "Intrathecal Pressure"

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Bal, Gabriella H., Katarina Stephen, Franco Bochicchio, Joel Kaye, Oleksandr Komarov, and Jonathan Forbes. "Quantitative Assessment of a Perfusion Pump Model Representing Intrathecal Pressure in a Cadaveric Model." In 33rd Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1780067.

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Supraptomo, Rth. "A Case Report on Regional Anaesthesia in Pregnant Women with Severe Pre-Eclampsia, Partial Hellp Syndrome, Fetal Distress, and Type II Diabetes Mellitus." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.05.29.

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ABSTRACT Background: Maternal mortality in Indonesia is caused by multifactors that are both direct and indirect factors. Complications during pregnancy and after delivery, including preeclampsia is the direct cause of 90% of maternal deaths. This case report aimed to describe the anaesthesia management on the incidence of severe preeclampsia to prevent the complications. Subjects and Method: We reported a 33-year-old G3P2A0 woman with 33 weeks of gestational age, diagnosed with severe pre-eclampsia partial HELLP syndrome, fetal dis-tress, type II diabetes mellitus pro SCTP emergency with phys
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