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1

Sjöstrand, Fredrik. "Volume kinetics of glucose solutions given by intravenous infusion /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-235-7/.

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2

Peña, Kristen Helen. "Characterization of an oxygen suspension used for intravenous infusion." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/75714.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2012.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 45).<br>Oxygenated fluid mixture can be used to treat critically ill patients suffering from asphyxia, lung injury, and cardiac arrest. This oxygenated fluid delivered intravenously re-oxygenates the bloodstream, allowing for more time to resuscitate a patient before they suffer brain and/or organ damage. The concentration of the mixture is crucial for treatment as it affects the viscosity of the fluid, which in turn af
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3

Ohmes, Cameon. "The disposition of lidocaine during a 6-hour intravenous infusion to young foals." Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/18832.

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Master of Science<br>Department of Clinical Sciences<br>Elizabeth Davis<br>Differences in pharmacokinetics and drug disposition exist between young and adult animals which become especially important for drugs with a narrow therapeutic index. While the pharmacokinetics and plasma concentrations of intravenous lidocaine have been studied in adult horses, determination of the disposition in foals is necessary before appropriate clinical use can be determined. This study examined the disposition of intravenous lidocaine in healthy (phase I) and hospitalized (phase II) foals. Phase I consisted of
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4

Zacchini, Federico <1986&gt. "Histological Study on Double Line of Intravenous Tacrolimus Infusion in Sla Defined Pig Model." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amsdottorato.unibo.it/7336/1/Zacchini_Federico_tesi.pdf.

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The immunosuppressive therapy still remains the only therapeutic strategy to control excessive immune activation following renal transplantation, but remain the problems related to excessive immunosuppression and in particular the toxicity due to high doses of immunosuppressive drugs such as calcineurin inhibitors. The present study has the aim of documenting, in a porcine animal model, the histological damage from calcineurin inhibitors using incremental doses of Tacrolimus, achieved in a limited amount of time, until it reaches toxic blood concentrations. We perform the study under different
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5

Zacchini, Federico <1986&gt. "Histological Study on Double Line of Intravenous Tacrolimus Infusion in Sla Defined Pig Model." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amsdottorato.unibo.it/7336/.

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The immunosuppressive therapy still remains the only therapeutic strategy to control excessive immune activation following renal transplantation, but remain the problems related to excessive immunosuppression and in particular the toxicity due to high doses of immunosuppressive drugs such as calcineurin inhibitors. The present study has the aim of documenting, in a porcine animal model, the histological damage from calcineurin inhibitors using incremental doses of Tacrolimus, achieved in a limited amount of time, until it reaches toxic blood concentrations. We perform the study under different
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6

Beths, Thierry. "Total intravenous anaesthesia in dogs : development of a target controlled infusion (TCI) scheme for propofol." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/354/.

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The aim of this work was to develop a propofol (PPF) based Total Intravenous Anaesthesia (TIVA) technique to be used in dogs by veterinary surgeons in practice. As PPF is a poor analgesic agent, this work also looked into the development of a co-infusion scheme for the potent alpha2-adrenoceptor agonist medetomidine (MED) and its active enantiomer dexmedetomidine (DEX). The study was divided into 4 phases. In phase one, canine PPF pharmacokinetic (PK) parameters, derived from previous studies reported in the literature, were incorporated to a Target Controlled Infusion (TCI) system. This appro
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7

Craig, R. P. "The modification of the metabolic response to injury by the infusion of different intravenous substrates." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375582.

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8

Debertolis, Letizia [Verfasser]. "Effects of an intravenous infusion of Escherichia coli lipopolysaccharide in early pregnant dairy cattle / Letizia Debertolis." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2015. http://d-nb.info/1073847209/34.

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9

Lawrence, Louann W. Delclos George L. "The effectiveness of a needleless intravenous system in prevention of percutaneous injury in two hospitals /." See options below, 1994. http://proquest.umi.com/pqdweb?did=741832391&sid=1&Fmt=2&clientId=68716&RQT=309&VName=PQD.

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10

Gerlach, Christina Anna [Verfasser]. "Continuous intravenous infusion anaesthesia following two different protocols for immobilisation in impala (Aepyceros melampus) / Christina Anna Gerlach." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2016. http://d-nb.info/1124853855/34.

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11

Tajik, Bashir. "DOES INTRAVENOUS GLUTAMATE INFUSION INFLUENCE THE USE OF INOTROPIC DRUGS IN PATIENTS OPERATED FOR ACUTE CORONARY SYNDROME?" Thesis, Linköpings universitet, Hälsouniversitetets läkarutbildning, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-129973.

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Introduction: In a double-blind randomized clinical trial (GLUTAMICS-ClinicalTrials.gov Identifier: NCT00489827), intravenous glutamate was associated with a risk reduction exceeding 50% for developing severe circulatory failure after isolated coronary artery bypass graft (CABG) for acute coronary syndrome (ACS). Here our aim was to investigate if glutamate also influenced the need or use of inotropes. Methods: Post hoc analysis of 824 patients in the GLUTAMICS-trial operated with isolated CABG for ACS. ICU-records were retrospectively scrutinized including hourly registration of inotropic dru
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12

Oe, Shoshiro. "Continuous intravenous infusion of deleted form of hepatocyte growth factor attenuates hepatic ischemia-reperfusion injury in rats." Kyoto University, 2002. http://hdl.handle.net/2433/149336.

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13

Rickard, Claire. "Prolonged use of intravenous administration sets: a randomised controlled trial." Thesis, Queensland University of Technology, 2004. https://eprints.qut.edu.au/15974/1/Claire_Rickard_Thesis.pdf.

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The purpose of this research study was to improve the nursing care of intravenous catheters by providing evidence on the effects of prolonged duration of intravenous administration set use. Intravenous therapy is a vital part of modern health care. However, its invasive nature can result in infection, with high associated morbidity and mortality. The highest infection rates are displayed in intensive care patients with central venous catheters. The duration of intravenous administration set use may have an impact on infection rates,however the current practice usage and the optimum durat
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14

Rickard, Claire. "Prolonged use of intravenous administration sets: a randomised controlled trial." Queensland University of Technology, 2004. http://eprints.qut.edu.au/15974/.

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The purpose of this research study was to improve the nursing care of intravenous catheters by providing evidence on the effects of prolonged duration of intravenous administration set use. Intravenous therapy is a vital part of modern health care. However, its invasive nature can result in infection, with high associated morbidity and mortality. The highest infection rates are displayed in intensive care patients with central venous catheters. The duration of intravenous administration set use may have an impact on infection rates,however the current practice usage and the optimum durat
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15

Dahlan, Winai. "Intravenous infusion of triacylglycerol-phospholipid complexes in man: effects on fatty acid pattern of plasma and on erythrocyte membrane lipid composition." Doctoral thesis, Universite Libre de Bruxelles, 1989. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213206.

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16

Arshad, Ali. "Phase II trial of the effect of gemcitabine with intravenous omega-3 fish oil infusion in patients with unresectable pancreatic adenocarcinoma." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/28133.

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Introduction Advanced Pancreatic Cancer (APC) has an appalling prognosis characterised by rapidly declining quality of life mediated by circulating pro-inflammatory cytokines and growth factors (CAF). Omega-3 fatty acids (n-3FAs) are proven to have antineoplastic and anti-inflammatory effects. Oral trials of n-3FAs in patients with advanced cancer have shown mixed results due in part to poor bioavailability and compliance with these preparations. Methods A phase II single arm trial was carried out using gemcitabine and intravenous n-3Fas in patients with APC. Primary outcome measure was overal
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17

Menegheti, Thais Mayara [UNESP]. "Diferentes taxas de infusão de tramadol na analgesia trans e pós-operatória imediata em cães submetidos a procedimentos ortopédicos: Thais Mayara Menegheti.-." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/88180.

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Made available in DSpace on 2014-06-11T19:23:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-05-27Bitstream added on 2014-06-13T19:49:54Z : No. of bitstreams: 1 000721479.pdf: 1511062 bytes, checksum: b30577204312e567fe62e47106cdefce (MD5)<br>Multimodal analgesia is being increasingly used in veterinary medicine and in that context, tramadol has demonstrated effectiveness in controlling moderate to severe pain. The present study aimed to investigate the influence of three rates of tramadol at continuous infusion for trans and post- operative analgesia of dogs undergoing orthopedi
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18

Castro, Vanessa Bastos [UNESP]. "Efeitos hemodinâmicos do cloridrato de dexmedetomidina administrado por infusão intravenosa contínua em cães anestesiados com propofol." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/105629.

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Made available in DSpace on 2014-06-11T19:35:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-29Bitstream added on 2014-06-13T21:07:06Z : No. of bitstreams: 1 castro_vb_dr_botfm.pdf: 811446 bytes, checksum: c21c255ab07d1f8809f7e545477272d8 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O emprego de procedimentos de anestesia intravenosa total em cães tem sido mais freqüente, devido ao melhor conhecimento do perfil farmacocinético dos fármacos empregados. Como ainda não existe um único fármaco que produza todas as características desejáveis em uma
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19

Castro, Vanessa Bastos. "Efeitos hemodinâmicos do cloridrato de dexmedetomidina administrado por infusão intravenosa contínua em cães anestesiados com propofol /." Botucatu : [s.n.], 2008. http://hdl.handle.net/11449/105629.

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Orientador: Antônio José de Araújo Aguiar<br>Banca: Stélio Pacca L. Luna<br>Banca: Silvia Gaido Cortopassi<br>Banca: Denise Tabacchi Fantoni<br>Banca: Reinaldo C. Braz<br>Resumo: O emprego de procedimentos de anestesia intravenosa total em cães tem sido mais freqüente, devido ao melhor conhecimento do perfil farmacocinético dos fármacos empregados. Como ainda não existe um único fármaco que produza todas as características desejáveis em uma anestesia geral, há a necessidade de se associar ao hipnótico, agentes com propriedades analgésicas. O objetivo desse estudo foi avaliar os efeitos hemodin
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20

Menegheti, Thais Mayara. "Diferentes taxas de infusão de tramadol na analgesia trans e pós-operatória imediata em cães submetidos a procedimentos ortopédicos / Thais Mayara Menegheti.-." Araçatuba [s.n.], 2013. http://hdl.handle.net/11449/88180.

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Resumo:A analgesia multimodal é cada vez mais empregada em medicina veterinária e, o tramadol, um analgésico opioide de ação central, tem demonstrado efetividade no controle da dor moderada. Com este trabalho, objetivou-se verificar a eficácia analgésica transoperatória promovida pelo tramadol, quando administrado por infusão contínua, em cães submetidos a cirurgias ortopédicas; observar as possíveis alterações cardiorrespiratórias e efeitos adversos; avaliar as concentrações plasmáticas de tramadol e do metabólito M1 e verificar o período de analgesia pós-operatória residual. Para isso, foram
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21

BahaaAldeen, Al-Trad. "Effects of Increasing Intravenous Glucose Infusions on Lactation Performance, Metabolic Profiles, and Metabolic Gene Expression in Dairy Cows." Doctoral thesis, Universitätsbibliothek Leipzig, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-38233.

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Knowledge on the precise effects of surplus glucose supply in dairy cows is limited by the lack of information on how intermediary metabolism adapts at different levels of glucose availability. Therefore, a gradual increase of glucose supply via intravenous glucose infusion was used in the present study to test the dose effect of surplus provision of glucose on the metabolic status and milk production of dairy cows. Furthermore, the effects of increasing levels of surplus glucose on mRNA expressions and activities of rate-limiting enzymes involved in hepatic gluconeogenesis were investigated.
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22

Lannoy, Damien. "Optimisation de la qualité et de l’efficacité des dispositifs médicaux de perfusion simple et complexe." Thesis, Lille 2, 2010. http://www.theses.fr/2010LIL2S033/document.

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La perfusion intraveineuse, continue ou intermittente, est un acte courant dans les services de soins bien que non dénué de risque. Différents dispositifs médicaux peuvent être employés pour permettre l’administration parfois simultanée de plusieurs substances actives. Ces dispositifs peuvent, de par leurs caractéristiques propres, générer des fluctuations plus ou moins importantes du débit massique de principe actif, c’est-à-dire la quantité de médicament administrée au patient par unité de temps. Le premier axe de travail concernant ces dispositifs médicaux est l’étude des prescriptions des
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23

Neville, Mariana Fontes Lima. "Uso perioperatório de solução cristaloide balanceada comparado ao de cloreto de sódio 0,9% em crianças submetidas à ressecção de tumor cerebral: ensaio clínico randomizado." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-21032019-094559/.

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Objetivo: O objetivo deste estudo foi avaliar se o uso de uma solução cristaloide balanceada induz menos alterações metabólicas do que o cloreto de sódio 0,9% em crianças submetidas à ressecção de tumor cerebral. Desenho: Estudo fase II, unicêntrico, de superioridade, randomizado e controlado, realizado no Instituto de Oncologia Pediátrica da Universidade Federal de São Paulo, Brasil. População: crianças com idade entre 6 meses e 12 anos submetidas à ressecção de tumor cerebral. Intervenção: O uso de uma solução cristaloide balanceada durante e após (por 24 horas) ressecção de tumor cerebral f
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24

Ferraz, Karina Coutinho 1986. "Efeitos da infusão intravenosa de metaloproteinase-2 da matriz recombinante humana (rhMMP-2) em respostas ß-adrenérgicas = Effects of intravenous infusion of recombinant human matrix metalloproteinase-2 (rhMMP-2) in ß-adrenergic responses." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310017.

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Orientador: José Eduardo Tanus dos Santos<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T15:51:02Z (GMT). No. of bitstreams: 1 Ferraz_KarinaCoutinho_D.pdf: 4092717 bytes, checksum: 304af959216055cd75432ac292abc300 (MD5) Previous issue date: 2012<br>Resumo: Evidências clínicas e experimentais indicam o envolvimento de metaloproteinases da matriz extracelular (MMPs) na patogênese de diversas doenças, incluindo as doenças cardiovasculares. Particularmente, alterações na atividade da MMP-2 parecem desempenhar um im
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25

Venter, J. C. "The safety and efficacy of the propofol/ Alfentanil/ Ketamine-bolus technique in midazolam pre-medicated patients undergoing office based plastic or reconstructive surgery." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8596_1255685962.

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<p>The purpose of this research project was to assess the safety and efficacy of a combination of drugs for conscious sedation in patients undergoing office-based plastic and reconstructive surgery. A pilot study was done to determine the safety of the co-administration of the drugs used in the sedation technique.</p>
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26

Perez, Maxime. "Evaluation de différentes stratégies de prévention des incompatibilités médicamenteuses dans le contexte de la perfusion continue." Thesis, Lille 2, 2015. http://www.theses.fr/2015LIL2S020/document.

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La perfusion intraveineuse occupe une large place dans les services de soins cliniques. Les patients reçoivent de nombreux médicaments simultanément dans la même voie centrale, où des problèmes de compatibilité entre les médicaments peuvent survenir. La maitrise de ces incompatibilités médicamenteuses, génératrices de particules, représente donc un enjeu majeur dans la prise en charge des patients polymédiqués.La première partie de ce travail est une analyse de la littérature portant sur les incompatibilités médicamenteuses et leurs principales conséquences sur le plan clinique. A ce titre, un
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27

Benlabed, Abdelmalik. "Évaluation de l’exposition du patient adulte aux particules issues des incompatibilités entre médicaments injectables utilisés en anesthésie et réanimation." Thesis, Lille 2, 2018. http://www.theses.fr/2018LIL2S028/document.

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Ce travail de doctorat s’inscrit dans un projet de recherche destiné à évaluer la charge particulaire issue des incompatibilités physico-chimiques d’origine médicamenteuse de patients admis en réanimation pour un état de choc septique ou un syndrome de détresse respiratoire aigüe. Le corollaire est de faire le lien avec la survenue de certaines complications (syndrome inflammatoire et dysfonction d’organe) susceptibles de menacer le pronostic vital. En effet, la dysfonction microcirculatoire caractéristique de ces patients pourrait être majorée par la contamination particulaire aboutissant ain
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28

Genay, Stéphanie. "Optimisation des montages de perfusion en anesthésie-réanimation : au travers d'expériences cliniques." Thesis, Lille 2, 2014. http://www.theses.fr/2014LIL2S060/document.

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Au cours de l’administration simultanée de plusieurs médicaments injectables, sont utilisées une ligne principale de perfusion et une ou plusieurs ligne(s) en dérivation. La ligne principale est directement reliée au cathéter et permet l’administration des solutions utilisées pour l’apport hydro-électrolytique ou de maintenir une voie d’abord veineuse perméable. Les autres thérapeutiques vont être perfusées en dérivation de cette ligne principale. La prise en charge des patients relevant de soins intensifs et de réanimation nécessite une polymédication. Les traitements d’urgence impliquent maj
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29

LIAO, YU-SIANG, and 廖育祥. "Build Optimal Assignment Model for Nursing Operation of Intravenous Infusion Applying Internet of Things – an Application of Smart Intravenous Infusion Controller." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/73727497039589464272.

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碩士<br>國立雲林科技大學<br>工業工程與管理系<br>104<br>A survey of the status of nursing staff showed that the most important reason influencing their job dissatisfaction is heavy workload. It causes nurses don't want to remain in office. On the other hand, according to factor analysis of hospital call bell, the most frequent problem is intravenous infusion injection. It not only interferes with nursing job but also produces care environmental noise which may affect the nurses’ working performance or patients’ psychological sentiment. Analysis current intravenous infusion operations, we found that nurses have n
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Chang, Chun-Hsiung, and 張俊雄. "A User Interface Design Investigation on Intravenous Infusion Monitoring System." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/n89z8m.

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碩士<br>國立臺灣科技大學<br>設計系<br>105<br>The intractable process of intravenous infusion therapy (IV infusion) has been a common problem that increasing the workload for nursing staff. Along with the development of eHealth promoted by Internet of things (IOTs) technology, remote monitoring IV infusion process is considered to be a novel solution to this long-standing problem. Also, at the time of building an intravenous infusion monitoring, it’s necessary to ensure not only the stable operation of the system but also the effective information transmission of the user interface (UI). After all, The user
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Huang, Yu-Chun, and 黃郁淳. "Influence of Intravenous Infusion Procedure on the Amikacin Serum Levels in Neonates." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/81075788992137864844.

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碩士<br>國立成功大學<br>臨床藥學研究所<br>92<br>Background: In the NICU of National Cheng Kung University Hospital (NCKUH), amikacin combined with ampicillin/sulbactam is the drug of choice in newborns of suspected nosocomial infection. The pharmacokinetic studies of amikacin in neonates had demonstrated significant inter-individual variability in drug distribution and elimination, especially in the low birth weight premature infants. The therapeutic drug monitoring (TDM) of amikacin in neonates has been recommended to ensure effectiveness and avoid toxic side effect, but a standard procedure has never been
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Chuan-Shin, Chen, and 陳傳炘. "Glucuronidation and Sulfation of Caffeic acid in Rabbits after Intravenous Infusion Administration." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/79705327031888072703.

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碩士<br>台北醫學院<br>藥學研究所<br>86<br>Caffeic acid (CA) is a natural phenolic compound. Its pharmacokinetic behaviors have been studied in rabbits with intravenous bolus and oral administration. However, literatures about the pharmacokinetic behaviors of CA in rabbits with intravenous infusion are scarce. The purpose of this study is the pharmacokinetic behaviors of CA in rabbit's urine after intravenous infusion administration. During the study, the concentration of CA in rabbits' plasma are maintained at the stea
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Ilan, Roy. "Time-to-alarm for intravenous infusion pumps: Implications and safety for critically ill patients." 2008. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=772100&T=F.

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34

Yue, Ying Kwan. "A Healthcare Failure Mode and Effect Analysis on the Safety of Secondary Infusions." Thesis, 2012. http://hdl.handle.net/1807/33603.

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Secondary infusions are a common and convenient method to administer intermittent infusions unattended through a single IV access using infusion pump technology. Previous studies have indicated that clinicians have a high frequency of committing operation errors while administering secondary infusions, which can cause patient harm. The purpose of this study was to evaluate the safety of secondary infusion practice by identifying and analyzing potential failure modes when delivering secondary infusions on five different smart infusion pumps. Healthcare Failure Mode and Effect Analysis (HFMEA) w
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Gabriel, Joseph. "Effect of Intravenous Saline Infusion and Venous Compression Stockings on Upper Airway Size and Obstruction." Thesis, 2011. http://hdl.handle.net/1807/30600.

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Obstructive sleep apnea (OSA) severity is strongly associated with the degree of overnight peripharyngeal fluid accumulation. We hypothesized that intravenous fluid loading would cause upper airway (UA) narrowing or increase the frequency of apneas and hypopneas per hour of sleep (apnea-hypopnea index; AHI). We employed a controlled, randomized double-crossover experiment in 9 healthy men aged 23-46 years. In the control, subjects were administered approximately 80 ml of normal saline intravenously during sleep. In the intervention, subjects were administered approximately 1850 ml of saline du
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Cheng, Yi-Ling, and 鄭怡齡. "Studies of the Comparison between Intravenous Infusion Set and Silicone T-drainage Tube in the Application of Peritoneal Dialysis in dogs." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/50685591683678099960.

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碩士<br>國立臺灣大學<br>獸醫學系<br>84<br>Peritoneal dialysis is an effetive way to treat the animals with renal failure. The aim of this study is to compare two cheap commercial products: intravenous infusion set and silicone T-drainage tube. By comparing the outflow rate, complications and the influence of the tubes to the organs in the peritoneal cavi- ty, we evaluate the effect of these types of materials and the possibility of their application . IV infusion set was implanted in six dogs and sili
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Tsai, Hung-Wen, and 蔡鴻文. "A model for assessing feasibility, safety, efficacy and cost-effectiveness of intensive continuous intravenous insulin infusion for blood glucose concentration control." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/81566113459613218552.

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碩士<br>國立陽明大學<br>醫務管理研究所<br>96<br>Background:Diabetes mellitus (DM) is a well-established risk factor for death and complication after cardiac surgery. Furthermore, hyperglycemia is very common in diabetic patients after surgery. Recent studies suggest that strict postoperative glycemic control improves clinical outcome after cardiac surgery. Intensive continuous intravenous insulin infusion is effective in lowing blood glucose (BG) concentration, in addition, reduces the postoperative mortality and morbidity rates in diabetic patients after cardiac surgery. Among several algorithms, protocols
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Li, Mengqing. "Stability studies of intravenous cyclosporine preparations stored in non-PVC containers." Thèse, 2012. http://hdl.handle.net/1866/9073.

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Dans cette étude, la stabilité de préparations intraveineuses de cyclosporine (0.2 et 2.5 mg/mL dans NaCl 0.9% ou dextrose 5%) entreposées dans des seringues de polypropylène, des sacs de polypropylène-polyoléfine et des sacs de vinyle acétate d’éthylène a été évaluée. Une méthode HPLC indicatrice de la stabilité à base de méthanol a été développée et validée suite a des études de dégradation forcée. Les solutions évaluées ont été préparées de façon aseptique, puis entreposées à 25°C. La stabilité chimique a été évaluée par HPLC et la stabilité physique a été évaluée par inspection visuelle et
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39

Fan, Mark. "Measuring the Impact of Human Factors and Education Informed Training on the Safety and Efficiency of Smart Infusion Technology." Thesis, 2009. http://hdl.handle.net/1807/18262.

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This thesis evaluated the effects of two types of training on nurses’ ability to safely and efficiently administer IV medications using a smart infusion pump. A high fidelity simulated nursing unit was created in which nurses recruited from the University Health Network programmed a series of infusions after receiving training. A training script modeled after the pump vendor’s training sessions was created and tested first on 24 nurses. The results were analyzed for deficiencies in safety and efficiency from a human factors and education perspective and a new training script was created and te
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Chan, Katherine Yin-Yee. "Mitigating Risks Associated with Secondary Intravenous Infusions: An Empirical Evaluation of a Technology-based, Training-based, and Practice-based Intervention." Thesis, 2013. http://hdl.handle.net/1807/42708.

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Secondary infusions is a common method to deliver short infusions of intravenous (IV) drugs and fluids. Errors associated with this infusion method have led to patient safety concerns. This study's objective was to empirically evaluate interventions to mitigate secondary infusion risks. Three interventions, including a technology-based intervention (clamp detector on a smart pump), a training-based intervention (educational module), and a practice-based intervention (use of a separate pump for short infusions), were tested in a simulated inpatient unit. The technology-based intervention signif
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BahaaAldeen, Al-Trad. "Effects of Increasing Intravenous Glucose Infusions on Lactation Performance, Metabolic Profiles, and Metabolic Gene Expression in Dairy Cows." Doctoral thesis, 2009. https://ul.qucosa.de/id/qucosa%3A11016.

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Knowledge on the precise effects of surplus glucose supply in dairy cows is limited by the lack of information on how intermediary metabolism adapts at different levels of glucose availability. Therefore, a gradual increase of glucose supply via intravenous glucose infusion was used in the present study to test the dose effect of surplus provision of glucose on the metabolic status and milk production of dairy cows. Furthermore, the effects of increasing levels of surplus glucose on mRNA expressions and activities of rate-limiting enzymes involved in hepatic gluconeogenesis were investigated.
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42

Howard, Elaina Charlotte. "Dopamine concentrations in nucleus accumbens subregions are differentially affected by ethanol administration." 2009. http://hdl.handle.net/2152/6539.

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Dopamine increases in the nucleus accumbens after contingent and noncontingent ethanol administration in rats, but the contributions of the core, coreshell border, and shell subregions to this response are unclear. Also, it is not fully understood if increases in dopamine under these circumstances are due to the pharmacological effects of ethanol, stimuli associated with administration, or both. The studies presented in this dissertation were conducted to investigate dopamine’s role in each of these accumbal regions during ethanol administration and presentation of associated stimuli. Using mi
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