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Journal articles on the topic 'Invasive fungal infection'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 July 2025

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1

Lee, Changhee, Yong Gi Jung, Hyo-Yeol Kim, and Sang Duk Hong. "Two Cases of Herpes Virus Infection of Nose Mimicking Acute Invasive Fungal Infection in Immunocompromised Hosts." Journal of Rhinology 29, no. 2 (2022): 106–11. http://dx.doi.org/10.18787/jr.2021.00387.

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Various invasive fungal infections can occur in immunocompromised hosts, and an acute invasive fungal infection (AIFI) can be fatal. Because of its high mortality rate, AIFI must be quickly diagnosed and treated, such as anti-fungal agents or surgical debridement. In an immunocompromised host, nasal herpes simplex infection, usually caused by herpes simplex virus (HSV) type-1, can have various clinical manifestations, some of which can mimic AIFI. However, the management of acute viral infection differs significantly from invasive fungal infections of the nose. A fast and accurate differential

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Cumbo, Thomas A., and Brahm H. Segal. "Prevention, Diagnosis, and Treatment of Invasive Fungal Infections in Patients with Cancer and Neutropenia." Journal of the National Comprehensive Cancer Network 2, no. 5 (2004): 455–69. http://dx.doi.org/10.6004/jnccn.2004.0036.

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Invasive fungal infections are a major cause of morbidity and mortality in patients with prolonged neutropenia and in allogeneic hematopoietic stem cell transplant recipients. The degree and duration of neutropenia influence the risk of opportunistic fungal infections. Because Candida and Aspergillus species are the major causes of invasive fungal infections in neutropenic patients, the fungal section of the NCCN guidelines focus on these two pathogens. Effective prevention and therapy of invasive fungal pathogens is a priority in highly immunocompromised patients with cancer. Three strategies

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Santamaría-Alza, Y., J. Sánchez-Bautista, J. F. Fajardo-Rivero, and C. L. Figueroa. "Invasive fungal infections in Colombian patients with systemic lupus erythematosus." Lupus 27, no. 7 (2018): 1116–22. http://dx.doi.org/10.1177/0961203318763743.

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Introduction Systemic lupus erythematosus is an autoimmune disease with multi-organ involvement. Complications, such as invasive fungal infections usually occur in patients with a greater severity of the disease. Objective The objective of this study was to determine the prevalence and risk variables associated with invasive fungal infections in a Colombian systemic lupus erythematosus population. Materials and methods A cross-sectional, retrospective study that evaluated patients with systemic lupus erythematosus for six years. The primary outcome was invasive fungal infection. Descriptive, g

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Narang, Himanshi, and Amit Patil. "Autopsy dissection techniques and investigations in deaths due to COVID-19 triggered fungal infections - A diagnostic review." Indian Journal of Forensic and Community Medicine 8, no. 4 (2021): 207–13. http://dx.doi.org/10.18231/j.ijfcm.2021.043.

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The COVID-19 pandemic, which originated from Wuhan, China, has rapidly spread worldwide, including India. As India grappled with the second wave, COVID-triggered fungal infection has suddenly risen tremendously, raising a sense of panic in the country. The fungal infection in COVID-19 includes Mucormycosis and Aspergillosis, as common fungal infections primarily affecting rhino-orbital structures. Many research papers have published postmortem findings in autopsies conducted on COVID-19 decedents, thereby helping to understand this contagious disease's pathogenesis. But, with the arrival of CO

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Nicolle, LE, C. Rotstein, AM Bourgault, G. St-Germain, and G. Garber. "Invasive Fungal Infections in Canada from 1992 to 1994." Canadian Journal of Infectious Diseases 9, no. 6 (1998): 347–52. http://dx.doi.org/10.1155/1998/473219.

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PURPOSE: To describe the frequency, characteristics and impact of invasive fungal infection in Canada.METHODS: Nominal case reporting with standardized data collection from selected sites across Canada. Cases were found primarily through laboratory review with supplementation by record review and clinical surveillance at some sites.RESULTS: The frequency of invasive fungal infection varied from 3.54 to 6.64/100,000 population per year.Candidaspecies were responsible for 66% of all reports; 80% of candidal infections were bloodstream isolates.Crytococcus neoformans,Aspergillusspecies andHistopl

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Buckley, H. R., M. D. Richardson, E. G. V. Evans, and L. J. Wheat. "Immunodiagnosis of invasive fungal infection." Medical Mycology 30, s1 (1992): 249–60. http://dx.doi.org/10.1080/02681219280000941.

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Castón-Osorio, J. J., A. Rivero, and J. Torre-Cisneros. "Epidemiology of invasive fungal infection." International Journal of Antimicrobial Agents 32 (November 2008): S103—S109. http://dx.doi.org/10.1016/s0924-8579(08)70009-8.

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LNU, Rijuneeta, and Bhumika Gupta. "Invasive Fungal Sinusitis." An International Journal Clinical Rhinology 5, no. 2 (2012): 63–71. http://dx.doi.org/10.5005/jp-journals-10013-1123.

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ABSTRACT Invasive sinus Aspergillus infection has been reported in the last decade with increased frequency, most commonly in the setting of hematologic malignancy, neutropenia, HIV infection and other states of immunosuppression. Fungal rhinosinusitis can be broadly classified into two varieties-invasive and noninvasive on the basis of tissue invasion. Invasive fungal sinusitis are acute invasive, chronic invasive (both granulomatous and nongranulomatous forms), whereas noninvasive are fungus balls and allergic fungal sinusitis. Invasive fungal sinusitis is one of the most challenging forms o

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Ahasan, HAM Nazmul, and Nawsabah Noor. "Common Invasive Fungal Infection in Bangladesh and Available Management." Journal of Bangladesh College of Physicians and Surgeons 41, no. 2 (2023): 164–69. http://dx.doi.org/10.3329/jbcps.v41i2.65105.

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Invasive fungal diseases are an important cause of mortality in immunocompromised patients and in patients with chronic illnesses. Multiple studies in Bangladesh have documented the frequency of fungal infections in our country and results varied. However, better understanding of the invasive fungal infection includes learning about the epidemiology, clinical features, and diagnostic method which is integral part of improving outcomes. In this review, we discuss the common invasive fungal infection that are prevalent in our country along with the clinical pictures, diagnosis, and treatment. It

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Van Dem, Pham, Dinh Thi Phuong Mai, Nguyen Thuy Giang, et al. "Clinical Characteristics Risk Factors Associated With Fungal Infections Among Preterm Infants." Journal of Neonatology 37, no. 1 (2023): 59–65. http://dx.doi.org/10.1177/09732179231157199.

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Objectives To examine clinical characteristics and factors associated with fungal blood infection among preterm neonates in a tertiary hospital in Vietnam. Methods A case-control study of 32 preterm neonates with fungal infection (cases) and 303 preterm infants without fungal infection (controls) were treated at the Neonatal Intensive Care Unit of the Pediatrics Department, Bach Mai Hospital, in 2019. Clinical and laboratory characteristics were collected. Multivariate logistic regression was used to identify factors associated with fungal infection. Results The rate of fungal infection was hi

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Swain, Satish, Kunal Sharma, Animesh Ray, et al. "Post-COVID-19-Invasive Pulmonary Mycosis." Libyan International Medical University Journal 07, no. 01 (2022): 007–11. http://dx.doi.org/10.1055/s-0042-1750711.

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COVID-19 has been associated with myriad manifestations as well as adverse outcomes. One of the less commonly reported consequences of COVID-19 is the occurrence of secondary infections in patients suffering acutely from COVID-19 or in those recuperating. Secondary invasive fungal infections (IFIs) have also been observed earlier in other viral infections such as influenza, parainfluenza, and respiratory syncytial virus infections. Severe lung damage and immunologic derangement resulting from SARS-CoV-2 infection predispose to superinfections. Risk factors for secondary IFI includes immunologi

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Dua, Kapil, H. Chopra, Neha Chopra, Sanjeev Puri, and Vikrant Mittal. "Invasive Fungal Rhinosinusitis: Our Experience." An International Journal Clinical Rhinology 2, no. 3 (2009): 21–26. http://dx.doi.org/10.5005/jp-journals-10013-1005.

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Abstract Opportunistic fungal infections in immunocompromised patients are associated with a high mortality rate. Endemic mycoses are often asymptomatic, but in appropriate hosts, fungi can cause severe and even fatal infection. Facial pain in an immunocompromised patient may signify invasive fungal sinusitis. Treatment with antifungal agents needs to be individualized according to factors such as the type of fungus, presence of renal failure, or pregnancy. Combining antifungal agents or addition of other approaches, such as surgical debridement or steps to control intracranial pressure, may b

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Cachera, Laurène, Antoine Adenis, Basma Guarmit, et al. "Invasive Fungal Infections in Persons Living with HIV in an Amazonian Context: French Guiana, 2009–2019." Journal of Fungi 7, no. 6 (2021): 421. http://dx.doi.org/10.3390/jof7060421.

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Although the burden of histoplasmosis in patients with advanced HIV has been the focus of detailed estimations, knowledge about invasive fungal infections in patients living with HIV in an Amazonian context is somewhat scattered. Our goal was thus to adopt a broader view integrating all invasive fungal infections diagnosed over a decade in French Guiana. All patients hospitalized at Cayenne hospital from 1 January 2009 to 31 December 2018 with a proven diagnosis of invasive fungal infection were included (N = 227). Histoplasmosis was the most common (48.2%), followed by Cryptococcus infection

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Pournezhad, Sam, Elaina Etter, and Rohit Mittal. "705 Evaluation of Invasive Fungal Infections in the Burn ICU." Journal of Burn Care & Research 44, Supplement_2 (2023): S129. http://dx.doi.org/10.1093/jbcr/irad045.180.

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Abstract Introduction Fungal infections are increasingly associated with critical illness, especially in major burn injury. The risk factors of invasive fungal infections include central venous catheter (CVC) placement, mechanical ventilation, broad-spectrum antibiotics, renal replacement therapy (RRT), and total parental nutrition. Critically ill burn patients have additional risk factors including extensive wounds, impaired immune system, and repeated surgical intervention. Despite significant morbidity and mortality caused by invasive fungal infections, efforts to prevent them with antifung

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Darfaoui, Loubna, Jihane Oussaga, Ayoub Belhaj, et al. "INVASIVE FUNGAL INFECTIONS IN COVID-19 PATIENTS IN THE INTENSIVE CARE UNIT: ABOUT 5 CASES." International Journal of Advanced Research 9, no. 10 (2021): 1132–36. http://dx.doi.org/10.21474/ijar01/13660.

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Covid-19 is a serious pathology it is associated with a deep immunodepression which favors invasive fungal infections especially in patients in intensive care unit. We report in our work a series of five covid-19 patients with fungal co-infection. We conducted a retrospective study including all COVID-19 patients hospitalized in intensive care unit for acute respiratory distress syndrome. Patients who presented a clinical worsening during their hospitalization were sampled with mycological study (bronchoalveolar lavage, serum and fungal blood culture). The diagnosis of fungal superinfection wa

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Scolarici, Michael, Margaret Jorgenson, Christopher Saddler, and Jeannina Smith. "Fungal Infections in Liver Transplant Recipients." Journal of Fungi 7, no. 7 (2021): 524. http://dx.doi.org/10.3390/jof7070524.

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Invasive fungal infections (IFIs) are one of the most feared complications associated with liver transplantation, with high rates of morbidity and mortality. We discuss the most common invasive fungal infections in the setting of liver transplant, including Candida, Aspergillus, and Cryptococcal infections, and some less frequent but devastating mold infections. Further, we evaluate the use of prophylaxis to prevent invasive fungal infection in this population as a promising mechanism to reduce risks to patients after liver transplant.

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Barbui, Anna Maria, Corrado Girmenia, and Giorgio Limerutti. "Diagnosis of invasive fungal infections." Reviews in Health Care 3, no. 1S (2012): 15. http://dx.doi.org/10.7175/rhc.42931s15-25.

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A proper diagnostic strategy of invasive fungal infections (IFI) is a very important component in the management of infectious complications in hematological patients. A good diagnostic approach should be adapted to the patient in relation to the underlying disease, stage of disease, localization of infection and immune status. None of the diagnostic markers can be entirely adopted for medical decision making, and sometimes it’s useful to use the combination of several microbiological tests.The diagnosis of IFI must therefore have a multidisciplinary approach that includes clinical suspicion,

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Barbui, Anna Maria, Corrado Girmenia, and Giorgio Limerutti. "Diagnosis of invasive fungal infections." Reviews in Health Care 3, no. 1S (2012): 15–25. http://dx.doi.org/10.7175/rhc.v3i1s.429.

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A proper diagnostic strategy of invasive fungal infections (IFI) is a very important component in the management of infectious complications in hematological patients. A good diagnostic approach should be adapted to the patient in relation to the underlying disease, stage of disease, localization of infection and immune status. None of the diagnostic markers can be entirely adopted for medical decision making, and sometimes it’s useful to use the combination of several microbiological tests.The diagnosis of IFI must therefore have a multidisciplinary approach that includes clinical suspicion,

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Shaheen, Shagufta, Shivanck Upadhyay, Creticus Petrov Marak, Gagan Kumar, and Achuta Kumar Guddati. "Outcomes of invasive fungal infections in hematopoietic stem cell transplant patients." Journal of Clinical Oncology 31, no. 15_suppl (2013): e18008-e18008. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e18008.

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e18008 Background: Invasive fungal infections are associated with higher mortality in hematopoietic stem cell transplant (HSCT) recipients despite the use of broad spectrum antifungal agents. With the increase in the number of patients undergoing HSCT and a newer array of immunosuppressants, it is necessary to examine the incidence and outcomes of fungal infection in this population. Methods: We used Nationwide Inpatient Sample from years 2000 to 2008 to examine the trends and outcomes of fungal infections in patients admitted for HSCT. We used ICD-9-CM codes to identify those with HSCT. Simil

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Debela, Negeri, and Solome Nekahiwot. "Invasive Fungal Disease Associated with COVID-19 Infection." European Journal of Preventive Medicine 12, no. 4 (2024): 103–10. http://dx.doi.org/10.11648/j.ejpm.20241204.13.

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While COVID-19 primarily attacks the lungs, its reach can extend to various organs. Patients battling severe cases, especially those in intensive care, face a heightened risk of secondary infections caused by fungi, bacteria, and even other viruses. This vulnerability stems from a weakened immune system due to the initial infection, extended hospital stays, and the use of medications that suppress the immune response. Fungal infections pose a significant threat, with aspergillosis, candidiasis, mucormycosis, Cryptococcus, pneumocystis, and even regional fungal strains being identified in COVID

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Ellis, Michael, Basel al-Ramadi, Ulla Hedström, Hussain Alizadeh, Victor Shammas, and Jörgen Kristensen. "Invasive fungal infections are associated with severe depletion of circulating RANTES." Journal of Medical Microbiology 54, no. 11 (2005): 1017–22. http://dx.doi.org/10.1099/jmm.0.46121-0.

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Serum RANTES (regulated on activation, normal T-cell expressed and secreted) concentrations were measured in 14 patients who had haematological malignancies and developed invasive fungal infections (three of them definite, eight probable and three possible). RANTES levels fell substantially from pre-chemotherapy values at the start of and throughout the fungal infection, and recovered in patients who survived the fungal infection. However, in patients who died from the invasive fungal infection, RANTES levels did not recover. For survivors the mean ± sd levels for RANTES were 7656 ± 877 pg ml−

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Nucci, Marcio, and Kieren A. Marr. "Emerging fungal diseases." Clinical Infectious Diseases 41, no. 4 (2005): 521–6. https://doi.org/10.5281/zenodo.13527828.

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(Uploaded by Plazi for the Bat Literature Project) The epidemiology of invasive fungal infection is evolving. Yeasts other than Candida albicans and molds other than Aspergillus fumigatus have emerged as significant causes of invasive mycoses in severely immunocompromised patients. Although, in some instances, these changes may be related to medical interventions, such as the use of antifungal agents in prophylaxis, in the majority of cases, they seem to be a consequence of changes in the host, such as more-severe immunosuppression or different types of immunosuppression impacting both risk pe

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Nucci, Marcio, and Kieren A. Marr. "Emerging fungal diseases." Clinical Infectious Diseases 41, no. 4 (2005): 521–6. https://doi.org/10.5281/zenodo.13527828.

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(Uploaded by Plazi for the Bat Literature Project) The epidemiology of invasive fungal infection is evolving. Yeasts other than Candida albicans and molds other than Aspergillus fumigatus have emerged as significant causes of invasive mycoses in severely immunocompromised patients. Although, in some instances, these changes may be related to medical interventions, such as the use of antifungal agents in prophylaxis, in the majority of cases, they seem to be a consequence of changes in the host, such as more-severe immunosuppression or different types of immunosuppression impacting both risk pe

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Nucci, Marcio, and Kieren A. Marr. "Emerging fungal diseases." Clinical Infectious Diseases 41, no. 4 (2005): 521–6. https://doi.org/10.5281/zenodo.13527828.

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(Uploaded by Plazi for the Bat Literature Project) The epidemiology of invasive fungal infection is evolving. Yeasts other than Candida albicans and molds other than Aspergillus fumigatus have emerged as significant causes of invasive mycoses in severely immunocompromised patients. Although, in some instances, these changes may be related to medical interventions, such as the use of antifungal agents in prophylaxis, in the majority of cases, they seem to be a consequence of changes in the host, such as more-severe immunosuppression or different types of immunosuppression impacting both risk pe

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Nucci, Marcio, and Kieren A. Marr. "Emerging fungal diseases." Clinical Infectious Diseases 41, no. 4 (2005): 521–6. https://doi.org/10.5281/zenodo.13527828.

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(Uploaded by Plazi for the Bat Literature Project) The epidemiology of invasive fungal infection is evolving. Yeasts other than Candida albicans and molds other than Aspergillus fumigatus have emerged as significant causes of invasive mycoses in severely immunocompromised patients. Although, in some instances, these changes may be related to medical interventions, such as the use of antifungal agents in prophylaxis, in the majority of cases, they seem to be a consequence of changes in the host, such as more-severe immunosuppression or different types of immunosuppression impacting both risk pe

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Blot, Stijn, Koenraad Vandewoude, and Dirk Vogelaers. "Discriminating invasive fungal infection from colonization." Critical Care 12, no. 2 (2008): 412. http://dx.doi.org/10.1186/cc6835.

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de Pauw, B. E., and F. Meunier. "The Challenge of Invasive Fungal Infection." Chemotherapy 45, Suppl. 1 (1999): 1–14. http://dx.doi.org/10.1159/000048465.

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Yong, Michelle K., Monica A. Slavin, and Dimitrios P. Kontoyiannis. "Invasive fungal disease and cytomegalovirus infection." Current Opinion in Infectious Diseases 31, no. 6 (2018): 481–89. http://dx.doi.org/10.1097/qco.0000000000000502.

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Lionakis, Michail S. "Primary immunodeficiencies and invasive fungal infection." Current Opinion in Infectious Diseases 32, no. 6 (2019): 531–37. http://dx.doi.org/10.1097/qco.0000000000000593.

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Al Salmi, I., A. M. Metry, F. Al Ismaili, et al. "Transplant tourism and invasive fungal infection." International Journal of Infectious Diseases 69 (April 2018): 120–29. http://dx.doi.org/10.1016/j.ijid.2018.01.029.

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Rianthavorn, P., and P. Prurapark. "Risk factors of infection-associated mortality in children with lupus nephritis in under-resourced areas." Lupus 28, no. 14 (2019): 1727–34. http://dx.doi.org/10.1177/0961203319882498.

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Introduction Treatment of lupus nephritis class III, IV and V with immunosuppressive therapy increases patient survival but poses a risk of infection-related mortality. This study was conducted to evaluate risk factors for fatal infection in children with lupus nephritis in under-resourced areas. Methods Medical records of patients, who were admitted to a tertiary-care university-based hospital from January 2002 to July 2018 with the diagnosis of systemic lupus erythematosus, were reviewed. Only patients aged less than 18 years with lupus nephritis and documented infection were included in the

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Phillips, Kynlon, Frank Cirrone, Tania Ahuja, Justin Siegfried, and John Papadopoulos. "Posaconazole versus voriconazole as antifungal prophylaxis during induction therapy for acute myelogenous leukemia or myelodysplastic syndrome." Journal of Oncology Pharmacy Practice 25, no. 2 (2018): 398–403. http://dx.doi.org/10.1177/1078155218806975.

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Objective Patients with acute myelogenous leukemia or myelodysplastic syndrome undergoing induction chemotherapy are at increased risk of invasive fungal infection due to prolonged, severe neutropenia. Due to this risk, national guidelines recommend invasive fungal infection prophylaxis in this population until the resolution of neutropenia. Although posaconazole has demonstrated superiority over fluconazole and itraconazole, there is limited evidence for voriconazole for invasive fungal infection prophylaxis in this population. Even less data are available comparing posaconazole and voriconaz

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Senoner, Thomas, Robert Breitkopf, Benedikt Treml, and Sasa Rajsic. "Invasive Fungal Infections after Liver Transplantation." Journal of Clinical Medicine 12, no. 9 (2023): 3238. http://dx.doi.org/10.3390/jcm12093238.

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Invasive fungal infections represent a major challenge in patients who underwent organ transplantation. Overall, the most common fungal infections in these patients are candidiasis, followed by aspergillosis and cryptococcosis, except in lung transplant recipients, where aspergillosis is most common. Several risk factors have been identified, which increase the likelihood of an invasive fungal infection developing after transplantation. Liver transplant recipients constitute a high-risk category for invasive candidiasis and aspergillosis, and therefore targeted prophylaxis is favored in this p

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Gur, Ivan, Anton Zilbert, Kochava Toledano, Michael Roimi, and Anat Stern. "Clinical impact of fungal colonization of burn wounds in patients hospitalized in the intensive care unit: a retrospective cohort study." Trauma Surgery & Acute Care Open 9, no. 1 (2024): e001325. http://dx.doi.org/10.1136/tsaco-2023-001325.

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BackgroundInvasive fungal infections in burn victims significantly increase mortality and hospitalization. The effect of fungal burn wound colonization has not been established.MethodsAll adult patients hospitalized in the intensive care unit (ICU) with burns ≥10% of total body surface area (TBSA) between 2005 and 2021 were included. Superficial swabs were collected whenever clinical suspicion of wound colonization was raised, and deep tissue samples were sent at any wound excision. The primary outcome was the incidence of invasive fungal infections defined as any deep tissue fungal infection

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Morris, Shaun K., Upton D. Allen, Sumit Gupta, and Susan E. Richardson. "Breakthrough Filamentous Fungal Infections in Pediatric Hematopoetic Stem Cell Transplant and Oncology Patients Receiving Caspofungin." Canadian Journal of Infectious Diseases and Medical Microbiology 23, no. 4 (2012): 179–82. http://dx.doi.org/10.1155/2012/957973.

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BACKGROUND: Caspofungin is an echinocandin class antifungal medication that is commonly used empirically in immunocompromised patients at high risk for invasive fungal disease.OBJECTIVE: To describe the clinical characteristics of breakthrough fungal infections in pediatric hematopoetic stem cell transplant recipients, and oncology and hematology patients receiving caspofungin.METHODS: A five-year retrospective review, from 2004 through 2008, of all cases of proven invasive filamentous fungal infection of children admitted to The Hospital for Sick Children (Toronto, Ontario) was conducted. A b

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Matsuhashi, Yoshiko, Shinsuke Takagi, Hisashi Yamamoto, et al. "Prophylactic and Preemptive Anti-Fungal Therapy after Cord Blood Transplantation: A Retrospective Analyses of 188 Adult Patients." Blood 108, no. 11 (2006): 5320. http://dx.doi.org/10.1182/blood.v108.11.5320.5320.

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Abstract Background: Therapeutic outcomes for hematological diseases have recently been markedly improved due to the introduction of hematopoietic stem cell transplantation (HSCT), improvement of therapeutic regimens, and advancement of support therapy. Although invasive fungal infections have been one of the major causes of morbidity and mortality after cord blood transplantation(CBT), proper prophylactic and therapeutic approach to them has not been clearly established yet. To address this, we performed retrospective analysis to assess the effectiveness and safety of various antifungal agent

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Sant, Kailashnath. "Invasive Fungal Sinusitis: An Overview." An International Journal of Otorhinolaryngology Clinics 1, no. 1 (2009): 45–48. http://dx.doi.org/10.5005/jp-journals-10003-1006.

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Abstract Currently two main categories of fungal sinusitis are described; invasive and noninvasive. The invasive type can be; 1. Acute, fulminant, 2. Chronic, indolent, and 3. Granulomatous type. The noninvasive types are more common of which Allergic fungal sinusitis is commonly present in almost all extensive polyposis cases in India. The other noninvasive type is mycetoma or fungal ball, which carries the best prognosis if treated surgically well. The acute invasive fugal infection of sinuses by mucormycosis is an aggressive opportunistic infection caused by phycomycetes, first described in

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Lehrnbecher, Thomas, Markus Kalkum, Jackson Champer, Lars Tramsen, Stanislaw Schmidt, and Thomas Klingebiel. "Immunotherapy in Invasive Fungal Infection - Focus on Invasive Aspergillosis." Current Pharmaceutical Design 19, no. 20 (2013): 3689–712. http://dx.doi.org/10.2174/1381612811319200010.

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Saba Zeb, Fakhra, Uzma Qayyum, Shazia Nisar, Syed Waqar Abbas, Faud Ahmad Siddiqi, and Sobia Mehreen. "Factors Associated with Outcome in Patients Managed for Invasive Fungal Infections at the Infectious Diseases Department of a Tertiary Care Hospital." Pakistan Armed Forces Medical Journal 73, no. 2 (2023): 427–30. http://dx.doi.org/10.51253/pafmj.v73i2.9308.

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Objective: To look for the factors associated with outcomes in patients managed for invasive fungal infections at the Infectious Diseases Department of a Tertiary Care Hospital Study Design: Comparative cross-sectional study Place and Duration of Study: Department of Infectious Diseases, Pak Emirates Military Hospital, Rawalpindi Pakistan,from Apr 2021 to Sep 2022. Methodology: A total of 90 patients with a different types of invasive fungal infections diagnosed by consultant infectious diseases were recruited. First, they were given standard treatment for fungal infection; t

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Postma, Maarten J., Robin de Vries, Harriet Christopherson, et al. "Cost-Effectiveness of Itraconazole for the Prophylaxis of Invasive Fungal Infections for Neutropenic Patients; a Study for 3 European Countries." Blood 106, no. 11 (2005): 3133. http://dx.doi.org/10.1182/blood.v106.11.3133.3133.

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Abstract Background: Invasive fungal infections present a leading cause of mortality and morbidity in neutropenic patients treated for hematologic malignancies. As the diagnosis and management of invasive fungal infections is difficult, effective antifungal prophylaxis is desirable. Itraconazole is a broad spectrum antifungal agent with activity against Candida species as well as Aspergillus species, whereas fluconazole primarily targets Candida. There is no published data comparing cost-effectiveness of both antifungal agents. Objective: To asses the cost-effectiveness of itraconazole compare

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Martin, Craig A. "Invasive Fungal Infections in the Critically Ill Patient." Journal of Pharmacy Practice 18, no. 1 (2005): 9–17. http://dx.doi.org/10.1177/0897190004273471.

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Invasive fungal infections have become an increasingly prevalent and disturbing problem in critically ill patients. The advent of broad-spectrum antibacterial therapy and immunosuppressant therapy, among other factors such as mechanical ventilation, places the intensive care patient at significant risk for infection with pathogenic fungi. Most patients who become infected with invasive fungi, especially Candida species, have been previously colonized with the offending organism, lending to the notion that colonization precedes infection inmany cases. Despite an ever-increasing array of antifun

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Yeo, Siew Fah, and Brian Wong. "Current Status of Nonculture Methods for Diagnosis of Invasive Fungal Infections." Clinical Microbiology Reviews 15, no. 3 (2002): 465–84. http://dx.doi.org/10.1128/cmr.15.3.465-484.2002.

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SUMMARY The incidence of invasive fungal infections has increased dramatically in recent decades, especially among immunocompromised patients. However, the diagnosis of these infections in a timely fashion is often very difficult. Conventional microbiologic and histopathologic approaches generally are neither sensitive nor specific, and they often do not detect invasive fungal infection until late in the course of disease. Since early diagnosis may guide appropriate treatment and prevent mortality, there has been considerable interest in developing nonculture approaches to diagnosing fungal in

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Baysal, Mehmet, Elif Umit, İbrahim Bekir Boz, Onur Kırkızlar, and Muzaffer Demir. "Fusarium Endophthalmitis, Unusual and Challenging Infection in an Acute Leukemia Patient." Case Reports in Hematology 2018 (2018): 1–3. http://dx.doi.org/10.1155/2018/9531484.

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Invasive fungal infections bring serious mortality and morbidity during the treatment of acute myeloid leukemia. Especially, mold infections are challenging, and each case is unique in feature. These cases are usually fatal, and there is no consensus regarding optimal treatment. AML patients receive antifungal prophylaxis and may further require IFI (invasive fungal infection) treatments, but fusarium mold infections are often unrecognized and could be overlooked. In this case report, we try to emphasize the importance of this infection with a high-risk AML patient.

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Taneja, Nitin Sagar, Toyaja M. Jadhav, Debasheesh Das, and Alok D. Sen. "Dual Invasive Pulmonary Mycosis in a Post Covid-19 Patient: An Autopsy Diagnosis." Annals of Pathology and Laboratory Medicine 11, no. 4 (2024): C41–52. http://dx.doi.org/10.21276/apalm.3294.

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Patients suffering from Covid19 associated lower respiratory tract infection are most often in an immunocompromised state and are indeed vulnerable to a host of bacterial and fungal infections. Among the fungi, common invaders include candidiasis, aspergillosis and mucormycosis. Aspergillosis is a relatively common fungal infection which has been widely reported to occur in patients suffering from or recently recovered Covid19 infection. The invasive form of this fungus, is, however, less commonly reported in literature. Invasive pulmonary mucormycosis is a relatively uncommon pulmonary fungal

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Rajesh, Asija, khanijau Rashmi, and Chopra Santosh. "TREATMENT APPROACHES FOR MANAGEMENT OF INVASIVE FUNGAL INFECTION: A REVIEW." International Journal of Current Pharmaceutical Review and Research 13, no. 3 (2021): 01–12. https://doi.org/10.5281/zenodo.12667050.

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Over the past few years the invasive fungal infections (IFIs) incidences has increased as thepopulations of patients at risk have continued to rise due to current situation in covid. Earlierdiagnosis and the subsequent usage of appropriate antifungal therapy become difficult, theseleads to a high mortality rate in patients with IFI management. Along with the widespread useof antifungal prophylaxis, the epidemiology of invasive fungal pathogens has also changed.Non-albicans fungus, Non-fumigatus fungus genus, and molds aside from fungus genusbecame additional common pathogens inflicting invasiv

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Rajesh, Chilaka, Utkarash Mishra, Elenjickal Elias John, et al. "Fearsome four- Fungal infections in renal transplant recipients." Indian Journal of Microbiology Research 11, no. 4 (2024): 283–90. https://doi.org/10.18231/j.ijmr.2024.049.

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To study the clinical presentation, diagnostic methods, treatment and outcomes of Invasive Aspergillosis Cryptococcal infection, Mucormycosis and Histoplasmosis in renal transplant recipients. : We performed a retrospective analysis of renal transplant recipients with four major fungal infections from January 2000 until December 2022 at a tertiary care centre in Southern India. This study was approved by the institutional ethical committee. We have identified these cases from the electronic records of the microbiology department and renal transplant outpatient clinic. A total of 1970 patients

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Kennedy, Cassie C., Kelly M. Pennington, Elena Beam, and Raymund R. Razonable. "Fungal Infection in Lung Transplantation." Seminars in Respiratory and Critical Care Medicine 42, no. 03 (2021): 471–82. http://dx.doi.org/10.1055/s-0041-1729173.

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AbstractInvasive fungal infections threaten lung transplant outcomes with high associated morbidity and mortality. Pharmacologic prophylaxis may be key to prevent posttransplant invasive fungal infections, but cost, adverse effects, and absorption issues are barriers to effective prophylaxis. Trends in fungal infection diagnostic strategies utilize molecular diagnostic methodologies to complement traditional histopathology and culture techniques. While lung transplant recipients are susceptible to a variety of fungal pathogens, Candida spp. and Aspergillus spp. infections remain the most commo

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Enoch, D. A., H. A. Ludlam, and N. M. Brown. "Invasive fungal infections: a review of epidemiology and management options." Journal of Medical Microbiology 55, no. 7 (2006): 809–18. http://dx.doi.org/10.1099/jmm.0.46548-0.

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Fungi are increasingly recognised as major pathogens in critically ill patients. Candida spp. and Cryptococcus spp. are the yeasts most frequently isolated in clinical practice. The most frequent filamentous fungi (moulds) isolated are Aspergillus spp., but Fusarium spp., Scedosporium spp., Penicillium spp., and Zygomycetes are increasingly seen. Several reasons have been proposed for the increase in invasive fungal infections, including the use of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics, and prosthetic devices and grafts, and more aggressive surgery. Patients w

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Hajek, Ann E., Thomas A. Everest, and Eric H. Clifton. "Accumulation of Fungal Pathogens Infecting the Invasive Spotted Lanternfly, Lycorma delicatula." Insects 14, no. 12 (2023): 912. http://dx.doi.org/10.3390/insects14120912.

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In the eastern United States, populations of the invasive spotted lanternfly, Lycorma delicatula, are abundant and spreading. Four species of naturally occurring entomopathogenic fungi have previously been reported as infecting these planthoppers, with two of these causing epizootics. Nymphal- and adult-stage lanternflies in Pennsylvania and New York were surveyed for entomopathogenic fungal infections from October 2021 to November 2023, and assays were conducted to confirm the pathogenicity of species that were potentially pathogenic. Beauveria bassiana was the most abundant pathogen, but we

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Wolf, Joshua, Joshua Wolf, Gabriela Maron, et al. "78. Non-Invasive Prediction of Invasive Fungal Infection by Plasma-Based Microbial Cell-Free DNA Next-Generation Sequencing (mcfDNA NGS) in Pediatric Patients with Relapsed or Refractory Leukemia." Open Forum Infectious Diseases 8, Supplement_1 (2021): S51. http://dx.doi.org/10.1093/ofid/ofab466.078.

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Abstract Background Diagnosis of invasive fungal infections (IFIs), a life-threatening complication of cancer therapy or hematopoietic cell transplantation (HCT) can be challenging, and IFI has poor outcomes. Prediction or early non-invasive diagnosis of IFI in high-risk hosts before onset of symptoms could reduce morbidity and mortality. Because non-invasive plasma mcfDNA NGS can detect invasive fungal infections, and may predict bloodstream infections in immunocompromised patients, we hypothesized that mcfDNA NGS might also predict invasive fungal infection before clinical presentation. Meth

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