Academic literature on the topic 'Invasomal Gel'

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Journal articles on the topic "Invasomal Gel"

1

Desai, Ujwala, Ujwala Desai, Mayuresh Jadhav, et al. "Formulation and evaluation of terbinafine hydrochloride invasomal gel for topical drug delivery." Journal of Research in Pharmacy 29, no. 3 (2024): 1209–26. https://doi.org/10.12991/jrespharm.1694393.

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The primary goal of the research was to develop topical invasomal gel of terbinafine hydrochloride with enhanced permeation and sustained drug release. Invasomes were formulated through a mechanical dispersion technique, employing blends of terpenes (citral and d-limonene) and soya phosphatidylcholine. The optimization process involved assessing parameters such as particle size, zeta potential, poly-dispersibility index (PDI), and entrapment efficacy. The invasomal gel, which underwent optimization, was evaluated for drug content, spreadability, viscosity, in vitro and ex vivo drug release, an
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2

Anna, Ruth Thomas* Eisha Ganju Rajni Dubey Bhaskar Kumar Gupta. "Formulation And Evaluation of Griseofulvin-Loaded Invasomal Gel for Efficient Topical Delivery to Treat Dermatophytosis." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1615–23. https://doi.org/10.5281/zenodo.15205280.

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The present study aimed to formulate and evaluate griseofulvin-loaded invasomal gel for efficient topical delivery in the treatment of dermatophytosis. Griseofulvin was encapsulated in invasomes using different formulations, and their entrapment efficiency, vesicle size, and stability were assessed. Formulation F3, with a high entrapment efficiency of 72.25% and an average vesicle size of 95.58 nm, exhibited superior characteristics. The in vitro drug release studies showed that the formulation achieved 98.12% cumulative drug release at 6 hours, indicating rapid release, while formulation F3 e
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3

S, Amareshwar, and Abbaraju Krishna Sailaja. "Development and Evaluation of Voriconazole Loaded Invasomes Gel for Enhanced Antifungal Activity." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1358–65. http://dx.doi.org/10.25258/ijpqa.15.3.42.

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Although it has limited solubility and poor permeability to the skin, voriconazole (VRC) is a viable choice for the topical treatment of fungal infections. Owing to these constraints, treating the inflection requires several injections over an extended period. The goal of this work was to produce a VRC invasome gel with improved topical antifungal activity. The Box-Behnken design (BBD) program was utilized to optimize the IVS after it was created using the thin-film hydration process. The optimized invasome formulation through BBD has 159.9 nm of vesicle size, 68.58% of entrapment efficiency,
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4

Al-Zheery, Worood Hameed, and Hanan Jalal Kassab. "Pharmacokinetic Study of Oral Disulfiram Suspension and Topical Transdermal Nano-Invasomes Gel in Wistar Rats." Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ) 7, no. 1 (2024): 159–63. http://dx.doi.org/10.54133/ajms.v7i1.1130.

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Background: Disulfiram (DSF), an FDA-approved pharmaceutical for the management of alcoholism, has demonstrated its efficacy against several kinds of cancer. DSF has limited solubility, a fast metabolism, a short duration of action, and instability in physiological environments, mostly caused by rapid degradation in the acidic gastric environment. Objective: A transdermal gel containing disulfiram, which was loaded into invasomes, was developed to improve the stability of DSF and enable its effective distribution to tumor tissues. Methods: This study included 72 Wistar rats weighing 200±35 g,
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5

Verma, Harshita, and Dr Pradeep Pal. "Formulation, Development and Evaluation of Invasomes Loaded Clotrimazole Gel for Fungal Treatment." Scholars Academic Journal of Pharmacy 11, no. 8 (2022): 113–16. http://dx.doi.org/10.36347/sajp.2022.v11i08.001.

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The transdermal route is an important pathway for localized or systemic effects. The stratum corneum, the outer layer of the skin, is an essential skin permeation barrier for many drugs. To overcome this barrier, several techniques have been developed, including the use of the vehicle and nanocarriers to improve drug penetration. Recently, different types of nanocarriers have been designed to improve the dermal and transdermal delivery of medicines like ‘INVASOME’. We made clotrimazole loaded invasome gel which is used in fungal treatment. The procedure used in formulation of invasomal gel is
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6

Jain, Shweta, Shalini Tripathi, and Pushpendra Kumar Tripathi. "Antiarthritic potential of berberine loaded invasomal gel." Phytomedicine Plus 2, no. 4 (2022): 100373. http://dx.doi.org/10.1016/j.phyplu.2022.100373.

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7

Motwani, Aakanksha, B. K. Dubey, Deepak Kumar Basedia, Mukesh Kumar Patel, Sunil Kumar Shah, and Vivek Singh Thakur. "Formulation and Characterization of Invasomes Gel of Bacitracin for Effective Treatment of Topical Disease." Saudi Journal of Medical and Pharmaceutical Sciences 10, no. 12 (2024): 895–901. https://doi.org/10.36348/sjmps.2024.v10i12.003.

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Topical drug administration is a localized drug delivery system anywhere in the body through Optimized invasomal formulation was sealed in 10ml glass vial and stored at refrigeration temperature (4 - 8°C) and room temperature for one month. Entrapment efficiency, physical appearance was determined at regular intervals ophthalmic, rectal, vaginal and skin as topical routes. Skin is one of the most readily accessible organs on human body for topical administration and is main route of topical drug delivery system. Invasomes are considered an inventive drug delivery system for the transdermal rou
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8

Chavan, Dhananjay, and Manish Kumar. "Formulation and Characterization of Isoconazole Loaded Invasomal Gel for Effective Antifungal Activity." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 02 (2024): 919–24. http://dx.doi.org/10.25258/ijddt.14.2.47.

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The characterization of isoconazole invasomal gel formulations (IG1–IG5) aimed to evaluate their physical attributes, drug content, and drug release kinetics for topical application. All formulations exhibited transparency and smooth texture, indicating uniform drug dispersion. While IG1 had an easily pourable consistency, IG4 displayed very good consistency, suggesting viscosity differences. Despite these variations, all formulations showed good homogeneity and high drug content, with IG4 leading in drug content percentage. Spreadability and viscosity varied among formulations, influencing ea
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9

Gupta, Isha, Syeda Nashvia Adin, Md Abdur Rashid, Yahya Alhamhoom, Mohd Aqil, and Mohd Mujeeb. "Linalool-Incorporated Synergistically Engineered Modified Liposomal Nanocarriers for Enhanced Transungual Delivery of Terbinafine against Onychomycosis." Materials 16, no. 12 (2023): 4424. http://dx.doi.org/10.3390/ma16124424.

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This work investigates the synthesis of linalool-containing invasomes for terbinafine (TBF-IN) in order to increase the solubility, bioavailability, and nail permeability of terbinafine (TBF) for transungual administration. TBF-IN was created utilising the thin-film hydration technique, and with the Box–Behnken design (BBD), optimisation was carried out. TBF-INopt were investigated for vesicle size, zeta potential, PDI (Polydispersity index), entrapment efficiency (EE) and in vitro TBF release. In addition, nail permeation analysis, TEM (transmission electron microscopy), and CLSM (confocal sc
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10

Bhat, Chetan T., Panchaxari M. Dandagi, Kishori P. Sutar, Pradnya G. Patted, and Shivaprasad S. Bevinakoppamath. "Enhanced Rheumatoid Arthritis Therapy: Formulation, Optimization, and In Vitro and Ex Vivo Characterization of Polyherbal-Loaded Invasomal Gel." Journal of Current Pharma Research 20, no. 9 (2024): 1–15. http://dx.doi.org/10.25166/jcpr.2024.20.9.1.

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