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1

Desai, Ujwala, Ujwala Desai, Mayuresh Jadhav, et al. "Formulation and evaluation of terbinafine hydrochloride invasomal gel for topical drug delivery." Journal of Research in Pharmacy 29, no. 3 (2024): 1209–26. https://doi.org/10.12991/jrespharm.1694393.

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The primary goal of the research was to develop topical invasomal gel of terbinafine hydrochloride with enhanced permeation and sustained drug release. Invasomes were formulated through a mechanical dispersion technique, employing blends of terpenes (citral and d-limonene) and soya phosphatidylcholine. The optimization process involved assessing parameters such as particle size, zeta potential, poly-dispersibility index (PDI), and entrapment efficacy. The invasomal gel, which underwent optimization, was evaluated for drug content, spreadability, viscosity, in vitro and ex vivo drug release, an
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2

Anna, Ruth Thomas* Eisha Ganju Rajni Dubey Bhaskar Kumar Gupta. "Formulation And Evaluation of Griseofulvin-Loaded Invasomal Gel for Efficient Topical Delivery to Treat Dermatophytosis." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1615–23. https://doi.org/10.5281/zenodo.15205280.

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The present study aimed to formulate and evaluate griseofulvin-loaded invasomal gel for efficient topical delivery in the treatment of dermatophytosis. Griseofulvin was encapsulated in invasomes using different formulations, and their entrapment efficiency, vesicle size, and stability were assessed. Formulation F3, with a high entrapment efficiency of 72.25% and an average vesicle size of 95.58 nm, exhibited superior characteristics. The in vitro drug release studies showed that the formulation achieved 98.12% cumulative drug release at 6 hours, indicating rapid release, while formulation F3 e
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3

S, Amareshwar, and Abbaraju Krishna Sailaja. "Development and Evaluation of Voriconazole Loaded Invasomes Gel for Enhanced Antifungal Activity." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1358–65. http://dx.doi.org/10.25258/ijpqa.15.3.42.

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Although it has limited solubility and poor permeability to the skin, voriconazole (VRC) is a viable choice for the topical treatment of fungal infections. Owing to these constraints, treating the inflection requires several injections over an extended period. The goal of this work was to produce a VRC invasome gel with improved topical antifungal activity. The Box-Behnken design (BBD) program was utilized to optimize the IVS after it was created using the thin-film hydration process. The optimized invasome formulation through BBD has 159.9 nm of vesicle size, 68.58% of entrapment efficiency,
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Al-Zheery, Worood Hameed, and Hanan Jalal Kassab. "Pharmacokinetic Study of Oral Disulfiram Suspension and Topical Transdermal Nano-Invasomes Gel in Wistar Rats." Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ) 7, no. 1 (2024): 159–63. http://dx.doi.org/10.54133/ajms.v7i1.1130.

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Background: Disulfiram (DSF), an FDA-approved pharmaceutical for the management of alcoholism, has demonstrated its efficacy against several kinds of cancer. DSF has limited solubility, a fast metabolism, a short duration of action, and instability in physiological environments, mostly caused by rapid degradation in the acidic gastric environment. Objective: A transdermal gel containing disulfiram, which was loaded into invasomes, was developed to improve the stability of DSF and enable its effective distribution to tumor tissues. Methods: This study included 72 Wistar rats weighing 200±35 g,
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Verma, Harshita, and Dr Pradeep Pal. "Formulation, Development and Evaluation of Invasomes Loaded Clotrimazole Gel for Fungal Treatment." Scholars Academic Journal of Pharmacy 11, no. 8 (2022): 113–16. http://dx.doi.org/10.36347/sajp.2022.v11i08.001.

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The transdermal route is an important pathway for localized or systemic effects. The stratum corneum, the outer layer of the skin, is an essential skin permeation barrier for many drugs. To overcome this barrier, several techniques have been developed, including the use of the vehicle and nanocarriers to improve drug penetration. Recently, different types of nanocarriers have been designed to improve the dermal and transdermal delivery of medicines like ‘INVASOME’. We made clotrimazole loaded invasome gel which is used in fungal treatment. The procedure used in formulation of invasomal gel is
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Jain, Shweta, Shalini Tripathi, and Pushpendra Kumar Tripathi. "Antiarthritic potential of berberine loaded invasomal gel." Phytomedicine Plus 2, no. 4 (2022): 100373. http://dx.doi.org/10.1016/j.phyplu.2022.100373.

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7

Motwani, Aakanksha, B. K. Dubey, Deepak Kumar Basedia, Mukesh Kumar Patel, Sunil Kumar Shah, and Vivek Singh Thakur. "Formulation and Characterization of Invasomes Gel of Bacitracin for Effective Treatment of Topical Disease." Saudi Journal of Medical and Pharmaceutical Sciences 10, no. 12 (2024): 895–901. https://doi.org/10.36348/sjmps.2024.v10i12.003.

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Topical drug administration is a localized drug delivery system anywhere in the body through Optimized invasomal formulation was sealed in 10ml glass vial and stored at refrigeration temperature (4 - 8°C) and room temperature for one month. Entrapment efficiency, physical appearance was determined at regular intervals ophthalmic, rectal, vaginal and skin as topical routes. Skin is one of the most readily accessible organs on human body for topical administration and is main route of topical drug delivery system. Invasomes are considered an inventive drug delivery system for the transdermal rou
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8

Chavan, Dhananjay, and Manish Kumar. "Formulation and Characterization of Isoconazole Loaded Invasomal Gel for Effective Antifungal Activity." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 02 (2024): 919–24. http://dx.doi.org/10.25258/ijddt.14.2.47.

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The characterization of isoconazole invasomal gel formulations (IG1–IG5) aimed to evaluate their physical attributes, drug content, and drug release kinetics for topical application. All formulations exhibited transparency and smooth texture, indicating uniform drug dispersion. While IG1 had an easily pourable consistency, IG4 displayed very good consistency, suggesting viscosity differences. Despite these variations, all formulations showed good homogeneity and high drug content, with IG4 leading in drug content percentage. Spreadability and viscosity varied among formulations, influencing ea
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Gupta, Isha, Syeda Nashvia Adin, Md Abdur Rashid, Yahya Alhamhoom, Mohd Aqil, and Mohd Mujeeb. "Linalool-Incorporated Synergistically Engineered Modified Liposomal Nanocarriers for Enhanced Transungual Delivery of Terbinafine against Onychomycosis." Materials 16, no. 12 (2023): 4424. http://dx.doi.org/10.3390/ma16124424.

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This work investigates the synthesis of linalool-containing invasomes for terbinafine (TBF-IN) in order to increase the solubility, bioavailability, and nail permeability of terbinafine (TBF) for transungual administration. TBF-IN was created utilising the thin-film hydration technique, and with the Box–Behnken design (BBD), optimisation was carried out. TBF-INopt were investigated for vesicle size, zeta potential, PDI (Polydispersity index), entrapment efficiency (EE) and in vitro TBF release. In addition, nail permeation analysis, TEM (transmission electron microscopy), and CLSM (confocal sc
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Bhat, Chetan T., Panchaxari M. Dandagi, Kishori P. Sutar, Pradnya G. Patted, and Shivaprasad S. Bevinakoppamath. "Enhanced Rheumatoid Arthritis Therapy: Formulation, Optimization, and In Vitro and Ex Vivo Characterization of Polyherbal-Loaded Invasomal Gel." Journal of Current Pharma Research 20, no. 9 (2024): 1–15. http://dx.doi.org/10.25166/jcpr.2024.20.9.1.

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Ibrahim, Tarek M., Nourhan A. Abdulla, and Mai A. Mohamed. "Investigating the efficacy of mirtazapine-embedded invasomal gel nanocarriers via I-optimal design for management of atopic dermatitis." Journal of Drug Delivery Science and Technology 92 (February 2024): 105395. http://dx.doi.org/10.1016/j.jddst.2024.105395.

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Dwivedi, Mohit, Vijay Sharma, and Kamla Pathak. "Pilosebaceous targeting by isotretenoin-loaded invasomal gel for the treatment of eosinophilic pustular folliculitis: optimization, efficacy and cellular analysis." Drug Development and Industrial Pharmacy 43, no. 2 (2016): 293–304. http://dx.doi.org/10.1080/03639045.2016.1239628.

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13

Salem, Heba F., Amr Gamal, Haitham Saeed, Marwa Kamal, and Alaa S. Tulbah. "Enhancing the Bioavailability and Efficacy of Vismodegib for the Control of Skin Cancer: In Vitro and In Vivo Studies." Pharmaceuticals 15, no. 2 (2022): 126. http://dx.doi.org/10.3390/ph15020126.

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Skin cancer is the most frequent cancer throughout the world. Vismodegib (VSD) is a hedgehog blocker approved for the prevention and treatment of skin cancer. VSD, however, is poorly bioavailable and has been linked to side effects. This work focused on designing a nano-invasome gel as a vehicle for enhancing the permeation, bioavailability, and efficacy of VSD. Additionally, the combined effect of terpenes and ethanol was studied on the permeation of VSD compared with liposomes. The prepared VSD-loaded invasomes (VLI) formulation included cineole (1%v/v), cholesterol (0.15%w/w), phospholipid
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Singh, Pawan, Gaurav Jain, Priyanka Namdev, and Akhlesh Singhai. "FORMULATION AND EVALUATION OF LULICONAZOLE LOADED INVASOMES GEL." Asian Journal of Pharmaceutical Education and Research 10, no. 4 (2021): 79. http://dx.doi.org/10.38164/ajper/10.4.2021.79-88.

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15

SALIH, Omar, and Entidhar MUHAMMED. "Preparation, Evaluation, and Histopathological Studies of Ondansetron-Loaded Invasomes Transdermal Gel." Journal of Research in Pharmacy 28(1), no. 28(1) (2024): 289–303. http://dx.doi.org/10.29228/jrp.696.

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16

Kumari, Sunitha, Omar Awad Alsaidan, Dibyalochan Mohanty, et al. "Development of Soft Luliconazole Invasomes Gel for Effective Transdermal Delivery: Optimization to In-Vivo Antifungal Activity." Gels 9, no. 8 (2023): 626. http://dx.doi.org/10.3390/gels9080626.

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Luliconazole (LZ) is a good candidate for the treatment of fungal infection topically but has limitations, i.e., poor solubility and poor permeability to skin. Due to these limitations, multiple administrations for a long time are required to treat the inflection. The aim of the present study was to develop the invasomes (IVS) gel of LZ to improve the topical antifungal activity. The IVS was prepared by the thin-film hydration method and optimized by Box-Bhekhen design software. The optimized LZIVS (LZIVSopt) has 139.1 ± 4.32 nm of vesicle size, 88.21 ± 0.82% of entrapment efficiency, 0.301 ±
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17

Eissa, Essam M., Amani M. El Sisi, Marina A. Bekhet, et al. "pH-Sensitive In Situ Gel of Mirtazapine Invasomes for Rectal Drug Delivery: Protruded Bioavailability and Anti-Depressant Efficacy." Pharmaceuticals 17, no. 8 (2024): 978. http://dx.doi.org/10.3390/ph17080978.

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The present research emphasizes fabrication alongside the assessment of an innovative nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine for rectal administration. This system could circumvent the confines of orally administered counterparts regarding dose schedules and bioavailability. Mirtazapine invasomes were tailored by amalgamating phospholipid, cineole, and ethanol through a thin-film hydration approach rooted in the Box–Behnken layout. Optimization of composition parameters used to fabricate desired NVMs’ physicochemical attributes was undertaken using th
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18

Salih, Omar Saeb, and Entidhar Jasim Al-Akkam. "Pharmacokinetic parameters of ondansetron in rats after oral solution and transdermal invasomes gel: A comparison study." Journal of Advanced Pharmacy Education and Research 13, no. 1 (2023): 116–21. http://dx.doi.org/10.51847/hs5a27ei6o.

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19

Singh, Yogesh, and Anjana Bhardwaj. "NEW RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF ANTIFUNGAL DRUG ITRACONAZOLE IN ITRACONAZOLE LOADED INVASOMES GEL." Journal of Advanced Scientific Research 12, no. 04 (2021): 263–67. http://dx.doi.org/10.55218/jasr.202112435.

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A new simple, accurate, rapid, selective and robust high pressure liquid chromatography (HPLC) method was developed and validated for estimation of itraconazole (ITZ) in bulk and prepared in house invasomes gel formulation. Acetonitrile and Methanol was used as a mobile phase for chromatographic separation in the ratio of 20mM KH2PO4: Acetonitrile (pH adjusted to 4.0 with OPA) at flow rate of 1.0 ml/min and estimation on Thermo C18 (250 × 4.6 mm) in the ratio of 50:50 v/v at flow rate of 1.0 ml/min. The detection was carried out with UV detector set at 262nm. The retention time for itraconazol
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Zafar, Ameeduzzafar, Mohd Yasir, Lubhan Singh, Mohammed Jafar, Musarrat Husain Warsi, and Dibya Sundar Panda. "Luteolin-loaded Invasomes Gel for Transdermal Delivery: Development, Optimization, <i>in-vitro</i>, and Preclinical Evaluation." Journal of Oleo Science 73, no. 9 (2024): 1221–40. http://dx.doi.org/10.5650/jos.ess24041.

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21

Bervald, Clauber Mateus Priebe, Cristina Rodrigues Mendes, Fabiana Carret Timm, Dario Munt de Moraes, Antônio Carlos Souza Albuquerque Barros, and Silmar Teichert Peske. "Desempenho fisiológico de sementes de soja de cultivares convencional e transgênica submetidas ao glifosato." Revista Brasileira de Sementes 32, no. 2 (2010): 09–18. http://dx.doi.org/10.1590/s0101-31222010000200001.

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O objetivo do trabalho foi avaliar a qualidade fisiológica de sementes de soja convencional e transgênica, das cultivares CD 216 e CD 212RR, submetidas ao glifosato. As sementes foram embebidas nas doses de zero; 1,8; 3,6; 5,4 e 7,2 g.L-1 de equivalente ácido de glifosato durante meia hora. Foram realizados os testes de primeira contagem da germinação, germinação, condutividade elétrica, índice de velocidade de emergência, emergência de plântula, comprimento de raízes e parte aérea, massa de matéria seca total. Concluiu-se que a qualidade fisiológica das sementes das cultivar CD 212RR é reduzi
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Marlaire, Simon, and Christoph Dehio. "Bartonella effector protein C mediates actin stress fiber formation via recruitment of GEF-H1 to the plasma membrane." PLOS Pathogens 17, no. 1 (2021): e1008548. http://dx.doi.org/10.1371/journal.ppat.1008548.

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Bartonellae are Gram-negative facultative-intracellular pathogens that use a type-IV-secretion system (T4SS) to translocate a cocktail of Bartonella effector proteins (Beps) into host cells to modulate diverse cellular functions. BepC was initially reported to act in concert with BepF in triggering major actin cytoskeletal rearrangements that result in the internalization of a large bacterial aggregate by the so-called ‘invasome’. Later, infection studies with bepC deletion mutants and ectopic expression of BepC have implicated this effector in triggering an actin-dependent cell contractility
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Zequeria Álvarez, María Elena, Rebeca González López del Castillo, Happy Salas Fuentes, and Yudirka Matos Sánchez. "Evaluación económica ambiental para el uso consuntivo del pino de Australia (casuarina equisetifolia) en el sector Amigos del Mar de la playa Santa Lucía de Camagüey, Cuba." REVISTA CIENTÍFICA ECOCIENCIA 7, no. 1 (2020): 1–19. http://dx.doi.org/10.21855/ecociencia.71.302.

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La playa “Santa Lucía”, Camagüey, Cuba cuenta con valores naturales importantes los que actualmente se comercializan con un destino turístico de sol y playa. El objetivo principal de este trabajo es realizar la valoración económica ambiental para el uso consuntivo del pino de Australia (Casuarina equisetifolia L.) en el sector de playa conocido Amigos del Mar. El área de intervención tiene 9,01 hectáreas comprendidas en los límites del sector Amigos del Mar. Las acciones, que incluyen su tala y destoconado, fueron contratadas a la Cooperativa de Construcción “Pirámide”. El procedimiento metodo
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Valdez N, Arianna, Iván Choez, Sofie Van Der Hende, Omar Ruìz, and Patricia Manzano. "Condiciones óptimas de extracción de compuestos antioxidante del alga roja Acanthophora spicifera." Bionatura 8, no. 1 (2023): 1–8. http://dx.doi.org/10.21931/rb/2023.08.01.11.

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La Acanthophora spicifera un alga roja de fácil adaptación a diferentes condiciones ambientales, por su capacidad de regenerarse por fragmentación, convirtiéndola en una especie invasora en áreas tropicales y subtropicales. Además, es conocida por sus componentes bioactivos (antioxidantes, fitohormonas, fitopigmentos). En este estudio se plantea determinar las condiciones óptimas de extracción de compuestos antioxidantes de la macroalga que crece en la zona intermareal de la playa de San Pedro de la provincia de Santa Elena, en dos procesos de secado (horno y liofilización) y extracción etanól
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Langoni, Hélio. "Os avanços em ciências agrárias." Veterinária e Zootecnia 25, no. 1 (2018): 9. http://dx.doi.org/10.35172/rvz.2018.v25.45.

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Nos últimos anos a inovação possibilitou ganhos para a ciência e tecnologia, resultando em práticas modernas tanto na produção de alimentos quanto nos diagnósticos de enfermidades em plantas e nos animais. No que diz respeito à Medicina Veterinária, atualmente é possível a utilização de equipamentos de última geração para o diagnóstico por imagem à semelhança da medicina humana, como tomografia e ressonância magnética. Hoje há centros especializados para dar suporte aos clínicos veterinários, incluindo-se centros especializados em endoscopia veterinária, com possibilidade de intervenção para p
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Sahu, Alakh N., Debadatta Mohapatra, and Pratap Chandra Acharya. "Nanovesicular ultraflexible invasomes and invasomal gel for transdermal delivery of phytopharmaceuticals." Nanomedicine, February 29, 2024. http://dx.doi.org/10.2217/nnm-2024-0029.

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Tweetable abstract Invasomes and invasomal gel are ultraflexible, soft vesicular, phospholipid based nanocarriers with deeper skin penetration ability for transdermal applications of drugs and phytopharmaceuticals.
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Samir, Bassant, Amal El-Kamel, Noha Zahran, and Lamia Heikal. "Resveratrol-loaded invasome gel: A promising nanoformulation for treatment of skin cancer." Drug Delivery and Translational Research, February 15, 2024. http://dx.doi.org/10.1007/s13346-024-01534-9.

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AbstractSkin cancer is a widespread type of cancer representing 30% of all cancer types worldwide. Resveratrol (RSV) is an anticancer drug used for skin cancer treatment. Several limitations of RSV such as poor aqueous solubility, first-pass metabolism, and instability limit their topical use. The study aimed to develop and optimize RSV-loaded invasomes for topical administration as well as assess their efficacy in vivo. The optimized RSV-loaded invasomes showed small particle size (208.7 ± 74 nm), PDI (0.3 ± 0.03), high % entrapment efficiency (77.7 ± 6%), and negative zeta potential (−70.4 ±
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Shankar, Ravi, Manish Kumar, and Prabhat Kumar Upadhyay. "Comparative Study on Enhanced Skin Permeation Efficiency of Phenylephrine via Novel Lipid Vesicles: A Promising Approach in Preventing Chemotherapy-Induced Alopecia Management." Current Pharmaceutical Biotechnology 26 (October 18, 2024). http://dx.doi.org/10.2174/0113892010336809240815050316.

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Background: Chemotherapy-induced alopecia (CIA) significantly impacts patients' emotional and psychological well-being and treatment regimen. Phenylephrine, a topical vasoconstrictor, can potentially reduce hair loss by limiting chemotherapy drug delivery to hair follicles. However, effective delivery of Phenylephrine through the skin remains challenging. This study investigates lipid vesicles as delivery vehicles to enhance Phenylephrine's skin permeation and sustained release due to their biocompatibility and encapsulation capabilities. Objective: This study aimed to formulate and compare di
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Dash, Deepak Kumar, Dibya Sundar Panda, Satyanarayan Pattnaik, Riya Vaiswade, and Gayatri Gupta. "Enhancing transdermal drug delivery: formulation and evaluation of simvastatin-loaded invasomes in carbopol gel for improved permeability and prolonged release." Brazilian Journal of Pharmaceutical Sciences 61 (2025). https://doi.org/10.1590/s2175-97902025e23976.

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Abstract The transdermal pathway serves as a significant route for achieving localized or systemic effects. Within this context, the stratum corneum is a crucial barrier limiting the permeation of many drugs. To surmount this barrier, carriers, and nanocarriers have been utilised, notably ‘invasome’ being one such example. In our study, we formulated invasomes loaded with simvastatin using the conventional thin-layer evaporation technique. This formulation involved the use of soy phosphatidylcholine, terpene (Limonene), chloroform, and ethanol. Simvastatin-loadedinvasomes were incorporated int
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Krishna sailaja, Abbaraju, and Thoudaboina Meghana. "FORMULATION AND EVALUATION OF INVASOMAL AND ETHOSOMAL GEL FOR CURCUMIN AND DETERMINATION OF ANTI- FUNGAL ACTIVITY." Current Nanomaterials 08 (March 29, 2023). http://dx.doi.org/10.2174/2405461508666230329122937.

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Background:-: Despite exhibiting anti-inflammatory, antiseptic, and anti-cancer properties, curcumin is not exhibiting the same efficacy as that other non-steroidal anti-inflammatory agents and anti-cancer drugs. The main reason is its poor solubility and poor permeability. To improve the solubility the particle size has to be reduced to the nano level and to improve the permeability vesicular drug delivery approaches have to be adapted. By developing invasomal and ethosomal gels the bioavailability of curcumin can be enhanced Aim and Objective:-: The main aim of the study is to develop Invaso
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Anitha, P., and S. V. Satyanarayana. "Design and optimization of nano invasomal gel of Glibenclamide and Atenolol combination: in vitro and in vivo evaluation." Future Journal of Pharmaceutical Sciences 7, no. 1 (2021). http://dx.doi.org/10.1186/s43094-021-00240-4.

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Abstract Background There are many circumstances where chronic disease is associated with other disorders, especially in diseases such as diabetes with noncommunicable disease risk factors, such as hypertension. The current therapies for treating such chronic comorbid diseases are limited and challenging due to the difficulties in overcoming the side effects from complex therapeutic treatment regimen. The present study is aimed to develop and optimize the combinational nano invasomal gel of Glibenclamide (GLB) and Atenolol (ATN) as a novel combination therapy for comorbid treatment of diabetic
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"Cytotoxic effect of transdermal invasomal anastrozole gel on MCF-7 breast cancer cell line." Journal of Applied Pharmaceutical Science 9, no. 3 (2019): 50–58. http://dx.doi.org/10.7324/japs.2019.90308.

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Kandekar, Ujjwala, Shriyash Lotake, Ashlesha Pandit, Atul Sayare, and Prashant Ghode. "Optimization of invasomal gel of miconazole nitrate for the treatment of topical fungal infections." Journal of Drug Delivery Science and Technology, November 2024, 106450. http://dx.doi.org/10.1016/j.jddst.2024.106450.

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Kumar, Bhumika, Pravat Kumar Sahoo, and Satish Manchanda. "Formulation, characterization and ex vivo study of curcumin nano-invasomal gel for enhanced transdermal delivery." OpenNano, July 2022, 100058. http://dx.doi.org/10.1016/j.onano.2022.100058.

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Ibrahim Al-Samadi, Inas Essam, Kareem Omar Rashwan, Rehab Abdelmonem, et al. "Topical loratadine-loaded invasomal gel repurposed for vulvovaginal candidiasis; in vitro, in silico, ex vivo, and in vivo studies." International Journal of Pharmaceutics, April 2025, 125639. https://doi.org/10.1016/j.ijpharm.2025.125639.

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Baiomy, Asmaa M., Mona K. Younis, Rasha M. Kharshoum, et al. "Optimized Delivery of Enalapril Maleate via Polymeric Invasomal In-Situ Gel for Glaucoma Treatment: In vitro, In vivo, and Histological studies." Journal of Drug Delivery Science and Technology, February 2025, 106685. https://doi.org/10.1016/j.jddst.2025.106685.

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Ahad, Abdul, Mohammad Raish, Yousef A. BinJardan, Abdullah M. Al-Mohizea, and Fahad I. Al-Jenoobi. "Development of eugenol fortified fisetin loaded nano-invasomes gel." Xenobiotica, March 13, 2025, 1–13. https://doi.org/10.1080/00498254.2025.2478928.

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Patil, Jayesh, Shraddha Gundawar, Pankaj Jain, and Shailesh Chalikwar. "Strategic Formulation of Losartan Potassium Nano-invasome Gel: A Comprehensive Multiscale Pharmacokinetic Study." BioNanoScience 15, no. 1 (2024). https://doi.org/10.1007/s12668-024-01610-x.

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Singh, Yogesh, and Anjana Bhardwaj. "Formulation Development and Evaluation of Itraconazole Loaded Invasomes Hydrogel." Journal of Pharmaceutical Research International, December 18, 2021, 657–65. http://dx.doi.org/10.9734/jpri/2021/v33i59b34430.

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Topical drug administration is a localized drug delivery system anywhere in the body through ophthalmic, rectal, vaginal and skin as topical routes. Skin is one of the most readily accessible organs on human body for topical administration and is main route of topical drug delivery system. There are various skin infections caused by fungus. An antifungal medication is a pharmaceutical fungicide used to treat mycoses such as athlete’s foot ringworm, candidiasis. Antifungal works by exploiting differences between mammalian and fungal cells to kill the fungal organism without dangerous effect on
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Verma, Shivani, and Puneet Utreja. "Exploring Therapeutic Potential Of Invasomes, Transfersomes, Transethosomes, Oleic Acid Vesicles, And Cubosomes Adopting Topical/Transdermal Route." Micro and Nanosystems 13 (April 6, 2021). http://dx.doi.org/10.2174/1876402913666210406163452.

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Abstract:
Background: Transdermal drug delivery is considered as a better alternative to oral administration of drugs like proteins or peptides that are susceptible to extensive degradation via first pass metabolism. This delivery route also shows high patient compliance due to no use of painful injections. Conventional delivery systems like creams and gel show poor skin permeation and high dosing frequency. Objective: The objective of this work was to investigate the role of highly advanced micro and nanocarrier systems like invasomes, transfersomes, transethosomes, oleic acid vesicles, and cubosomes f
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"ESTUDIO PRELIMINAR DE LA VARIABILIDAD INTRAESPECÍFICA DE PROTEÍNAS SEMINALES EN Araujia hortorum FOURN (Apocynaceae)." Revista ECIPeru, January 16, 2019, 28–31. http://dx.doi.org/10.33017/reveciperu2006.0016/.

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ESTUDIO PRELIMINAR DE LA VARIABILIDAD INTRAESPECÍFICA DE PROTEÍNAS SEMINALES EN Araujia hortorum FOURN (Apocynaceae). PRELIMINAR STUDY OF THE INTRASPECIFIC VARIABILITY OF SEED PROTEINS IN Araujia hortorum FOURN (Apocynaceae) Gonzales Medrano, M.F, Galvez, M.J , González, S.R y Villamil, C.B DOI: https://doi.org/10.33017/RevECIPeru2006.0016/ RESUMEN Araujia hortorum Fourn es una enredadera perenne sudamericana que se comporta como invasora en cultivos y en áreas de reserva natural. Han habido controversias sobre la conveniencia de considerarla como especie independiente o como entidad infraespe
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