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Journal articles on the topic 'Invasome'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Dehio, C., M. Meyer, J. Berger, H. Schwarz, and C. Lanz. "Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome." Journal of Cell Science 110, no. 18 (1997): 2141–54. http://dx.doi.org/10.1242/jcs.110.18.2141.

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Vascular colonisation by Bartonella henselae may cause vaso-proliferative tumour growth with clumps of bacteria found in close association with proliferating endothelial cells. By using B. henselae-infected human umbilical vein endothelial cells as an in vitro model for endothelial colonisation, we report here on a novel mechanism of cellular invasion by bacteria. First, the leading lamella of endothelial cells establishes cellular contact to sedimented bacteria and mediates bacterial aggregation by rearward transport on the cell surface. Subsequently, the formed bacterial aggregate is engulfe

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Verma, Harshita, and Dr Pradeep Pal. "Formulation, Development and Evaluation of Invasomes Loaded Clotrimazole Gel for Fungal Treatment." Scholars Academic Journal of Pharmacy 11, no. 8 (2022): 113–16. http://dx.doi.org/10.36347/sajp.2022.v11i08.001.

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The transdermal route is an important pathway for localized or systemic effects. The stratum corneum, the outer layer of the skin, is an essential skin permeation barrier for many drugs. To overcome this barrier, several techniques have been developed, including the use of the vehicle and nanocarriers to improve drug penetration. Recently, different types of nanocarriers have been designed to improve the dermal and transdermal delivery of medicines like ‘INVASOME’. We made clotrimazole loaded invasome gel which is used in fungal treatment. The procedure used in formulation of invasomal gel is

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S, Amareshwar, and Abbaraju Krishna Sailaja. "Development and Evaluation of Voriconazole Loaded Invasomes Gel for Enhanced Antifungal Activity." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1358–65. http://dx.doi.org/10.25258/ijpqa.15.3.42.

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Although it has limited solubility and poor permeability to the skin, voriconazole (VRC) is a viable choice for the topical treatment of fungal infections. Owing to these constraints, treating the inflection requires several injections over an extended period. The goal of this work was to produce a VRC invasome gel with improved topical antifungal activity. The Box-Behnken design (BBD) program was utilized to optimize the IVS after it was created using the thin-film hydration process. The optimized invasome formulation through BBD has 159.9 nm of vesicle size, 68.58% of entrapment efficiency,

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Farouk, Hanan O., Marwa M. Nagib, Amr Gamal Fouad, et al. "Fabrication of an In Situ pH-Responsive Raloxifene-Loaded Invasome Hydrogel for Breast Cancer Management: In Vitro and In Vivo Evaluation." Pharmaceuticals 17, no. 11 (2024): 1518. http://dx.doi.org/10.3390/ph17111518.

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Background/Objectives: Raloxifene (RLF) is a therapeutic option for invasive breast cancer because it blocks estrogen receptors selectively. Low solubility, limited targeting, first-pass action, and poor absorption are some of the challenges that make RLF in oral form less effective. This study aimed to create an intra-tumoral in situ pH-responsive formulation of RLF–invasome (IPHRLI) for breast cancer treatment, with the goals of sustaining RLF release, minimizing adverse effects, and enhancing solubility, bioavailability, targeting, and effectiveness. Methods: Numerous RLF–invasome formulati

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Gamal, Amr, Shawky M. Aboelhadid, Fatma I. Abo El-Ela, et al. "Synthesis of Carvacrol-Loaded Invasomes Nanoparticles Improved Acaricide Efficacy, Cuticle Invasion and Inhibition of Acetylcholinestrase against Hard Ticks." Microorganisms 11, no. 3 (2023): 733. http://dx.doi.org/10.3390/microorganisms11030733.

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Carvacrol is a monoterpenoid phenol found in many essential oils that has antibacterial, antifungal and antiparasitic activities. Drug loaded-invasome systems are used to deliver drugs utilizing nanoparticles to improve bioavailability, efficacy, and drug release duration. As a result, the present study developed carvacrol-loaded invasomes and evaluated their acaricidal effect against Rhipicephalus annulatus (cattle tick) and Rhipicephalus sanguineus (dog tick). Carvacrol loaded-invasome (CLI) was prepared and characterized using UV/Vis spectrophotometer, zeta potential measurements, Scanning

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Babaie, Soraya, Azizeh Rahmani Del Bakhshayesh, Ji Won Ha, Hamed Hamishehkar, and Ki Hyun Kim. "Invasome: A Novel Nanocarrier for Transdermal Drug Delivery." Nanomaterials 10, no. 2 (2020): 341. http://dx.doi.org/10.3390/nano10020341.

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Invasomes are novel vesicular systems that exhibit improved transdermal penetration compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and terpene in their structures; these components confer suitable transdermal penetration properties to the soft vesicles. The main advantages of these nanovesicles lie in their ability to increase the permeability of the drug into the skin and decrease absorption into the systemic circulation, thus, limiting the activity of various drugs within the skin layer. In this paper, several features of invasomes, including their structu

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Patil, Shivaji, and Sushil Bhargav. "Invasomes: A Novel Transdermal Approach for Antifungal Drug Delivery." International Journal of Drug Delivery Technology 15, no. 02 (2025): 01–08. https://doi.org/10.25258/ijddt.15.2.63.

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Management of fungal infections, for those affecting skin, has faced challenges in poor penetration and efficacy. Traditional topical antifungal therapies often show limited results due to the skin’s barrier properties. Invasomes, has emerged as a greater tactic to improve drug penetration through skin, improving penetration and effectiveness of antifungal drugs. This review comprehensively analyzes invasomes as a transdermal drug delivery system specifically for antifungal therapies. It covers structure, composition, and mechanism of action of invasomes, Focusing on their advantages over conf

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Vieira Nunes Cunha, Izi, Angela Machado Campos, Adriana Passarella Gerola, and Thiago Caon. "Effect of invasome composition on membrane fluidity, vesicle stability and skin interactions." International Journal of Pharmaceutics 646 (November 2023): 123472. http://dx.doi.org/10.1016/j.ijpharm.2023.123472.

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9

Mohite, Chakradhar Hucche Bhimashankar Kazi Wasim Kolsure Shripal. "Invasomes: Potential Nanocarrier System for Transdermal Delivery of Drug Molecule." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2652–64. https://doi.org/10.5281/zenodo.15440759.

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Transdermal drug delivery refers to the drug administration route through the skin that achieves the local or systemic treatment approved for clinical use. Invasomes are novel vesicular systems that exhibit improved transdermal penetration compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and terpene in their structures; these components confer suitable transdermal penetration properties to the soft vesicles. Ethanol, terpenes and phospholipids are the key structural composition, systematize physicochemical properties of invasomes. Nanovesicles can enhance the

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Salem, Heba F., Amr Gamal, Haitham Saeed, Marwa Kamal, and Alaa S. Tulbah. "Enhancing the Bioavailability and Efficacy of Vismodegib for the Control of Skin Cancer: In Vitro and In Vivo Studies." Pharmaceuticals 15, no. 2 (2022): 126. http://dx.doi.org/10.3390/ph15020126.

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Skin cancer is the most frequent cancer throughout the world. Vismodegib (VSD) is a hedgehog blocker approved for the prevention and treatment of skin cancer. VSD, however, is poorly bioavailable and has been linked to side effects. This work focused on designing a nano-invasome gel as a vehicle for enhancing the permeation, bioavailability, and efficacy of VSD. Additionally, the combined effect of terpenes and ethanol was studied on the permeation of VSD compared with liposomes. The prepared VSD-loaded invasomes (VLI) formulation included cineole (1%v/v), cholesterol (0.15%w/w), phospholipid

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Ghalwash, Maha M., Amr Gamal Fouad, Nada H. Mohammed, et al. "Fabrication and In Vivo Evaluation of In Situ pH-Sensitive Hydrogel of Sonidegib–Invasomes via Intratumoral Delivery for Basal Cell Skin Cancer Management." Pharmaceuticals 18, no. 1 (2024): 31. https://doi.org/10.3390/ph18010031.

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Background/Objectives: Basal cell skin cancer (BCSC) develops when skin cells proliferate uncontrollably. Sonidegib (SDB) is a therapeutic option for the treatment of BCSC by inhibiting hedgehog signaling. The problems with SDB’s low solubility, poor bioavailability, resistance, poor targeting, and first-pass action make it less effective when taken orally. This investigation set out to design an intratumoral in situ pH-sensitive hydrogel of SDB-invasomes (IPHS-INV) that can effectively treat BCSC by improving SDB’s bioavailability, sustainability, targeting, and efficacy while also reducing i

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Truttmann, M. C., B. Misselwitz, S. Huser, W. D. Hardt, D. R. Critchley, and C. Dehio. "Bartonella henselae engages inside-out and outside-in signaling by integrin 1 and talin1 during invasome-mediated bacterial uptake." Journal of Cell Science 124, no. 21 (2011): 3591–602. http://dx.doi.org/10.1242/jcs.084459.

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Truttmann, Matthias C., Patrick Guye, and Christoph Dehio. "BID-F1 and BID-F2 Domains of Bartonella henselae Effector Protein BepF Trigger Together with BepC the Formation of Invasome Structures." PLoS ONE 6, no. 10 (2011): e25106. http://dx.doi.org/10.1371/journal.pone.0025106.

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Rhomberg, Thomas A., Matthias C. Truttmann, Patrick Guye, Yvonne Ellner, and Christoph Dehio. "A translocated protein ofBartonella henselaeinterferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome." Cellular Microbiology 11, no. 6 (2009): 927–45. http://dx.doi.org/10.1111/j.1462-5822.2009.01302.x.

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15

Truttmann, Matthias C., Thomas A. Rhomberg, and Christoph Dehio. "Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells." Cellular Microbiology 13, no. 2 (2010): 284–99. http://dx.doi.org/10.1111/j.1462-5822.2010.01535.x.

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Marlaire, Simon, and Christoph Dehio. "Bartonella effector protein C mediates actin stress fiber formation via recruitment of GEF-H1 to the plasma membrane." PLOS Pathogens 17, no. 1 (2021): e1008548. http://dx.doi.org/10.1371/journal.ppat.1008548.

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Bartonellae are Gram-negative facultative-intracellular pathogens that use a type-IV-secretion system (T4SS) to translocate a cocktail of Bartonella effector proteins (Beps) into host cells to modulate diverse cellular functions. BepC was initially reported to act in concert with BepF in triggering major actin cytoskeletal rearrangements that result in the internalization of a large bacterial aggregate by the so-called ‘invasome’. Later, infection studies with bepC deletion mutants and ectopic expression of BepC have implicated this effector in triggering an actin-dependent cell contractility

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Desai, Ujwala, Ujwala Desai, Mayuresh Jadhav, et al. "Formulation and evaluation of terbinafine hydrochloride invasomal gel for topical drug delivery." Journal of Research in Pharmacy 29, no. 3 (2024): 1209–26. https://doi.org/10.12991/jrespharm.1694393.

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The primary goal of the research was to develop topical invasomal gel of terbinafine hydrochloride with enhanced permeation and sustained drug release. Invasomes were formulated through a mechanical dispersion technique, employing blends of terpenes (citral and d-limonene) and soya phosphatidylcholine. The optimization process involved assessing parameters such as particle size, zeta potential, poly-dispersibility index (PDI), and entrapment efficacy. The invasomal gel, which underwent optimization, was evaluated for drug content, spreadability, viscosity, in vitro and ex vivo drug release, an

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18

Trigo, María del Mar, and José García-Sánchez. "Ambrosia artemisiifolia L., nueva especie para la flora alóctona invasora de Andalucía (España)." Acta Botanica Malacitana 31 (December 1, 2006): 203–5. http://dx.doi.org/10.24310/abm.v31i31.7161.

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Ambrosia artemisiifolia, a new species for the aloctonous invasive flora of Andalusia (Spain)Palabras clave. Ambrosia artemisiifolia, planta invasora, Andalucía, España.Key words. Ambrosia artemisiifolia, invasive plant, Andalusia flora, Spain.

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Shobana, K. "A Versatile Platform of Novel Approaches in Transdermal Delivery." International Journal for Research in Applied Science and Engineering Technology 12, no. 8 (2024): 1190–95. http://dx.doi.org/10.22214/ijraset.2024.64063.

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Abstract: Comprising of phospholipids, ethanol, and terpene, invasomes exhibit suitable transdermal penetration properties for soft vesicles. In comparison to liposomes and ethosomes, invasomes penetrate deeper into the skin. The ability to access the skin subcaste enhances the effectiveness of invasomes, which exert their effects by fluidizing the bilayer structure of stratum corneum (SC) lipids and disrupting lipid and intracellular protein interactions. They offer various advantages, including enhancing medication efficacy, improving patient compliance, and enhancing comfort. Over all the e

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Juan, Pedro Ruiz-Allais, Benayahu Yehuda, and Miguel Lasso-Alcalá Oscar. "The invasive octocoral Unomia stolonifera (Alcyonacea, Xeniidae) is dominating the benthos in the Southeastern Caribbean Sea." Memoria de la Fundación La Salle de Ciencias Naturales 79, no. 187 (2021): 63–80. https://doi.org/10.5281/zenodo.4784709.

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<strong>Abstract.</strong> The Indo-Pacific octocoral <em>Xenia</em> sp. has been reported as a successful invasive species of the Venezuelan coral reefs (Southeastern Caribbean Sea), and the first xeniid octocoral with such invasive properties. This taxon has been recently identified, and assigned to a new genus and combination as <em>Unomia stolonifera</em>. Since its first appearance there, it has dispersed along the shallow reefs, overgrowing any hard substrate, including corals and seagrass. Quantitative surveys revealed that <em>U. stolonifera</em> dominated all studied sites, featuring

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Cerovac, Anis, and Dubravko Habek. "Viable invasive cervical pregnancy treated with minimally invasive procedures." Česká gynekologie 88, no. 5 (2023): 380–82. http://dx.doi.org/10.48095/cccg2023380.

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Summary: With an incidence of 1% of all ectopic pregnancies, cervical ectopic pregnancy (CEP) is due to possible early misdiagnosis or bleeding and rupture can become a life-threatening condition with the need for urgent hysterectomy, which has been seen in clinical practice recently. We present a case of early diagnosed invasive CEP treated with combined minimally invasive procedure (MIP) due to acute pelvic pain and bleeding. In our case, we applied several of these methods to a primigravida with early invasive CEP with fertility preservation. By combining the self-described local medication

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Altamirano, María, Antonio Román Muñoz, Julio De la Rosa, et al. "The invasive species Asparagopsis taxiformis (Bonnemaisoniales, Rhodophyta) on Andalusian coast (Southern Spain): Reproductive stages, new records and invaded communities." Acta Botanica Malacitana 33 (December 1, 2008): 5–15. http://dx.doi.org/10.24310/abm.v33i0.6963.

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ABSTRACT. The invasive species Asparagopsis taxiformis (Bonnemaisoniales, Rhodophyta) on Andalusian coasts (Southern Spain): reproductive stages, new records and invaded communities. The present study provides new records from Andalusian coasts of the exotic invasive seaweed Asparagopsis taxiformis (Delile) Trevisan. These records demonstrate that A. taxiformis has rapidly and widely expanded its distribution range in this region, from Almería to Cádiz (Strait of Gibraltar). The latter locality may represent the western geographical limit of the species in the Mediterranean Sea. Spermatangial

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Casimiro-Soriguer, Federico, and Andrés V. Pérez Latorre. "Aproximación al conocimiento de la flora alóctona de la provincia de Málaga (España): catálogo de metáfitos." Acta Botanica Malacitana 33 (December 1, 2008): 373–82. http://dx.doi.org/10.24310/abm.v33i0.7009.

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SMITH, GIDEON F. "Refinements to the infra-sectional classification of Kalanchoe [subg. Bryophyllum] sect. Invasores (Crassulaceae subfam. Cotyledonoideae) at the rank of series: description of K. [subg. Bryophyllum sect. Invasores] ser. Invasores, K. [subg. Bryophyllum sect. Invasores] ser. Fruticosa, and K. [subg. Bryophyllum sect. Invasores] ser. Herbacea." Phytotaxa 698, no. 4 (2025): 196–208. https://doi.org/10.11646/phytotaxa.698.4.1.

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Three new series, Kalanchoe [subg. Bryophyllum sect. Invasores] ser. Invasores, K. [subg. Bryophyllum sect. Invasores] ser. Fruticosa, and K. [subg. Bryophyllum sect. Invasores] ser. Herbacea (Crassulaceae subfam. Cotyledonoideae), are described to accommodate, respectively, [1] a biennial, weak-stemmed species; [2] a mostly perennial, shrubby group of species with brittle-woody stems; and [3] a mostly herbaceous, soft-stemmed group of species, all of which are included in K. [subg. Bryophyllum]. The type, K. delagoensis, of K. [subg. Bryophyllum] sect. Invasores is also the type of K. ser. In

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Jesús, Antonio Bello-Pulido, Marval Ugas Francisco, Avendaño Neida, et al. "Presencia en el estado Sucre (Venezuela) de la especie invasora Crotalaria lanceolata E. Mey. (Leguminosae-Faboideae)." Memoria de la Fundación La Salle de Ciencias Naturales 80, no. 189 (2022): 5–9. https://doi.org/10.5281/zenodo.6387519.

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<strong>Resumen</strong>. Se presenta el primer registro de la especie invasora <em>Crotalaria lanceolata</em> para el estado Sucre. Las muestras objeto de este estudio fueron encontradas creciendo en dos áreas de vegetación secundaria correspondientes a los linderos del Parque Nacional Mochima en el estado Sucre. La primera ubicada en la localidad de Barbacoas y la segunda en Nurucual, ambas poblaciones fueron localizadas en diferentes períodos del año 2020. La presencia de individuos en estado reproductivo (flores y frutos) y sus típicas hojas lineares-lanc

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Del Egido Mazuelas, Fermín, Emilio Puente García, and Mª José López Pacheco. "Notas sobre flora alóctona leonesa." Acta Botanica Malacitana 32 (December 1, 2007): 215–20. http://dx.doi.org/10.24310/abm.v32i0.7038.

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Pulgar Sañudo, Íñigo, Patricia Ortega Olmo, and José Manuel Herrera Rodríguez. "Oenothera speciosa Nutt. (Onagraceae) en la provincia de Sevilla (España)." Acta Botanica Malacitana 43 (November 9, 2018): 149–50. http://dx.doi.org/10.24310/abm.v43i0.4867.

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Oenothera speciosa Nutt. (Onagraceae) in the province of Seville (Spain). Palabras clave: Planta adventicia, invasora, nueva cita, Sevilla. Key Words: Adventitious plant, invasive plant, new record, Seville.

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Ruiz de Gopegui, Antonio, and Yolanda Ruiz. "Aportaciones a la flora de la montaña palentina y su área de influencia. Contributions to the Palencia’s mountain flora and its influence area." Acta Botanica Malacitana 37 (November 6, 2019): 188–96. http://dx.doi.org/10.24310/abm.v37i0.2691.

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Contributions to the Palencia’s Mountain flora and its influence area. Palabras clave. Corología, flora amenazada, flora invasora, Palencia, España. Key words. Chorology, Endangered plants, Invasive plants, Palencia, Spain.

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Patil, Shivaji, and Sushil Bhargav. "Advanced invasomal delivery system for enhanced topical application of bifonazole in fungal infections." Prospects in Pharmaceutical Sciences 23, no. 1 (2025): 102–10. https://doi.org/10.56782/pps.317.

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The design and development of invasomes containing bifonazole for effective topical fungal treatment was investigated to improve the bioavailability and therapeutic efficacy of this antifungal agent. Invasomes, novel lipid-based vesicular systems, were formulated to enhance skin penetration and provide sustained drug release, thereby increasing the local concentration of bifonazole at the site of infection. The formulation was optimized using response surface methodology (RSM), where various factors such as phosphatidylcholine, terpenes, and ethanol were varied to evaluate their effects on ent

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Aluán, Adid, Diego Aguayo, and Domingo Pérez Bejarano. "Aspergilosis invasiva de vías aéreas." Revista del Nacional (Itauguá) 15, no. 2 (2023): 93–96. http://dx.doi.org/10.18004/rdn2023.dic.02.093.096.

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Es poco común encontrar en la literatura casos de traqueobronquitis invasiva por aspergillus que se manifiesten como tumores endobronquiales que produzcan atelectasia pulmonar total. Aunque relatada en inmunocomprometidos, la morbimortalidad es considerable aun en pacientes sin enfermedad de base.

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Mr. Ajay Kumar, Mr Ajay Kumar, Dr Shailesh Jain Dr. Shailesh Jain, Dr Dhanraj Patidar Dr. Dhanraj Patidar, Mr Ritesh Raj Mr. Ritesh Raj, Miss Pooja Yadav Miss Pooja Yadav, and Mr Prince Mishra Mr. Prince Mishra. "Topical Use of Celecoxib-Loaded Invasom: Development, Speciality, and In Vitro Skin Penetration Research." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1516–35. https://doi.org/10.35629/4494-100215161535.

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A potential approach to targeted therapy, particularly for inflammatory diseases like arthritis, is the topical administration of medications. The usefulness of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in treating pain and inflammation is hampered by its low skin penetration when given topically. In order to improve the therapeutic efficacy of celecoxib while reducing systemic adverse effects, this thesis investigates the creation, characterisation, and invitro skin penetration of celecoxib-loaded invasomes as a cutting-edge drug delivery method.Human skin served as the model

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Pooja, Rathore* Mukesh kumar Mohini Ghodke Mukesh kumar Jayaswal Niraj Kushwaha Neelesh Jhade Nikhil Shukla. "Topical Application of Celecoxib Loaded Invasom Development, Characteristics and in- Vitro Skin Penetration Studies." International Journal of Scientific Research and Technology 2, no. 5 (2025): 634–43. https://doi.org/10.5281/zenodo.15534477.

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The topical delivery of drugs presents a promising strategy for localized treatment, especially for inflammatory conditions like arthritis. Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is commonly used to treat pain and inflammation; however, its limited skin penetration when applied topically limits its effectiveness. This thesis explores the development, characterization, and in-vitro skin penetration of celecoxib-loaded invasomes as an advanced drug delivery system aimed at enhancing the therapeutic efficacy of celecoxib while minimizing systemic side effects. The formulation

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Nieves Arellano, A., HC Gutiérrez Vargas, JS Rodríguez González, et al. "From Non-Invasive to Invasive Diagnosis in Pleural Tuberculosis: Case Series and Literature Review." Series of Clinical and Medical Case Reports and Reviews 2, no. 2 (2024): 1–6. http://dx.doi.org/10.54178/2993-3579.v2i2a2028.

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Introduction: Tuberculosis (TB) in Mexico is considered an endemic public health problem. Infection in adults is caused 95% of the time by Mycobacterium tuberculosis (Mtb). Although non-invasive diagnostic techniques are the first choice, the diagnostic yield of these techniques does not always allow definitive diagnosis, so sometimes, surgical biopsy is necessary. Objective: To describe two cases of pleural TB with a difficult diagnosis in which non-invasive diagnostic tests were inconclusive. Conclusion: In the presence of pleural or pulmonary nodules or tumors, we should consider TB as a di

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Syahrir, Syakri, Muhammad Palinrungi, Prihantono Prihantono, and Muhammad Faruk. "Synchronous invasive urothelial cell carcinoma of the bladder with chronic myeloid leukemia." International Journal of Surgery and Medicine 5, no. 3 (2019): 1. http://dx.doi.org/10.5455/ijsm.synchronous-invasive-urothelial-cell-carcinoma.

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Swapnil, K. Shelke1 &. Dr. Deepak S. Dhote2. "ENUMERATEBLOOD HEMOGLOBIN BY NON-INVASIVE TECHNIQUES: A REVIEW." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES [NC-Rase 18] (November 15, 2018): 152–61. https://doi.org/10.5281/zenodo.1488753.

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Blood consists of many parameters such as hemoglobin, oxygen, white blood cell, red blood cell, platelets and plasma.  Hemoglobin is the main parameter of human blood, which carries oxygen from the lungs to the other parts of the body and carries carbon di-oxide back to the lungs from other parts of the body.   Measurement of hemoglobin helps a medical practitioner to diagnose several diseases as the health condition of patient.  Nowadays, Invasive methods are used to measure the hemoglobin concentration, where blood is taken from the patient and subsequently analyzed. Apar

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Gürpınar, Öznur, Alper Ergin, Pınar Zarakolu, and Özgen Köseoğlu Eser. "İnvaziv ve İnvaziv Olmayan Acinetobacter baumannii İzolatlarında Biyofilm Yapımı ve Virülans Genlerinin Varlığı." Flora the Journal of Infectious Diseases and Clinical Microbiology 26, no. 4 (2021): 720–26. http://dx.doi.org/10.5578/flora.20219618.

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Nascimento, Ladivania Medeiros do, Willams Ramos da Silva, and Uilian Do Nascimento Barbosa. "Espécies exóticas no fragmento de mata atlântica do Jardim Botânico do Recife: levantamento e classificação." Revista Arrudea - A revista do Jardim Botânico do Recife 7, no. 1 (2021): 18. http://dx.doi.org/10.55513/arrudea0043.

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Diante do papel dos jardins botânicos na criação de coleções de plantas, a introdução de espécies exóticas muitas vezes ocorre, podendo algumas delas apresentar potencial invasor da flora nativa e provocar prejuízo à vegetação. Assim, este trabalho teve como objetivo identificar e classificar as espécies exóticas do fragmento de Mata Atlântica onde está inserido o Jardim Botânico do Recife (JBR) e investigar, com base na literatura, suas interferências. Para tanto, foram feitas incursões no fragmento para registro de localização e classificação no status de invasora (I), não invasora (NI) e co

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Salih, Omar Saeb, and Entidhar J. Al-Akkam. "Preparation, In-vitro, and Ex-vivo Evaluation of Ondansetron Loaded Invasomes for Transdermal Delivery." Iraqi Journal of Pharmaceutical Sciences( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 32, no. 3 (2023): 71–84. http://dx.doi.org/10.31351/vol32iss3pp71-84.

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Invasomes are newly developed types of nanovesicles. A vesicular drug delivery system is considered one of the approaches for transdermal delivery to enhance permeation and improve drug bioavailability. Ondansetron is a serotonin receptor antagonist used for treating vomiting associated with different clinical cases. The study aimed to prepare invasomal dispersions for improving permeation of ondansetron across the skin with a controlled release pattern. Twenty-seven formulas of ondansetron-loaded invasomes were prepared by a modified mechanical dispersion method. These formulas were optimized

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Eisha, Ganju Rajni Dubey Anna Ruth Thomas Bhaskar Kumar Gupta. "Invasomes A Novel Drug Delivery for Transdermal Drug Delivery System." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1607–14. https://doi.org/10.5281/zenodo.15205214.

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Invasomes are a novel class of elastic phospholipid vesicles designed to enhance the percutaneous penetration of drugs, offering an improved alternative to conventional liposomes. These vesicles are composed of phosphatidylcholine, ethanol, and a variety of terpenes, which are known to significantly enhance skin penetration. Terpenes, such as citral, limonene, and cineole, disrupt the stratum corneum lipids, interact with intracellular proteins, and improve the partitioning of drugs into the skin, facilitating better drug absorption. Ethanol further enhances the vesicle's ability to penetrate

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Bello-Lemus, Víctor Hugo, Zapiain Fernando Torres, and Blanca Olivia Murillo-Ortiz. "Patrón de crecimiento invasor en adenomas hipofisarios con inmunohistoquímica hormonal positiva." Revista Médica del Instituto Mexicano del Seguro Social 63, no. 2 (2025): e6409. https://doi.org/10.5281/zenodo.14617045.

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<strong>Resumen</strong> <strong>Introducción: </strong>el adenoma hipofisario es el tumor más frecuente de la región selar, generalmente es benigno, sin embargo, el crecimiento invasor paraselar y/o supraselar puede afectar estructuras importantes causando alta morbimortalidad. <strong>Objetivo: </strong>Determinar el patrón de crecimiento invasor de los adenomas hipofisarios y su relación con el marcaje hormonal positivo por inmunohistoquímica. <strong>Material y métodos: </strong>en el periodo de marzo 2020 a marzo 2022 se incl

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De Medeiros, Jailma Dos Santos, Francisco De Oliveira Mesquita, Leonaldo Alves De Andrade, Cleiton José De Oliveira, Edlânia Maria De Souza, and Jânio Kleiber Camelo De Souza. "Invasão biológica por Cryptostegia madagascariensis: uma abordagem voltada para estresses abióticos." Pesquisa e Ensino em Ciências Exatas e da Natureza 2, no. 1 (2018): 36. http://dx.doi.org/10.29215/pecen.v2i1.579.

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<p style="text-align: justify;">A introdução, acidental ou deliberada, de espécies exóticas por diferentes vetores é atualmente uma das principais mudanças globais, resultando em uma série de problemas. Embora nem todas as introduções de espécies não nativas possuam efeitos negativos, muitos desses táxons podem desencadear efeitos indesejáveis sobre a biodiversidade, desde o nível genético até o nível de paisagens. Este trabalho visou apresentar o conhecimento atual sobre as invasões biológicas por espécies vegetais, particularmente, sobre a invasora <em>Cryptostegia madagascariens

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Bukowska, D., B. Kempisty, H. Piotrowska, et al. "The invasive and new non-invasive methods of mammalian oocyte and embryo quality assessment: a review." Veterinární Medicína 57, No. 4 (2012): 169–76. http://dx.doi.org/10.17221/5913-vetmed.

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&nbsp;The quality of oocytes-embryos can be determined by several techniques, including morphological, molecular, cellular and biochemical ones. The morphological methods of female gamete or embryo quality assessment often use thе following in vitro manipulation procedures such as: in vitro maturation (IVM), in vitro fertilization (IVF) and in vitro embryo production (IVP). However, these methods are highly subjective and the morphological classification of oocytes or embryos is not always compatible with their ability to grow and develop. Additionally, molecular biology methods are object

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Bachir Bouiadjra, Benabdellah, Nourredine Belbachir, Mokhtar Youcef Benkada, Abderrezak Maarouf, and Hassane Riadi. "Sur la presence de l’algue marine Caulerpa racemosa (Forsskal) J. Agardh (Caulerpales, Chlorophyta) devant la côte Mostaganemoise (ouest Algerie). Sobre la presencia de Caulerpa racemosa (Forsskal) J. Agardh (Caulerpales, Chlorophyta) en la costa de Mostaganemoise (O de Argelia)." Acta Botanica Malacitana 35 (December 1, 2010): 168–71. http://dx.doi.org/10.24310/abm.v35i0.2862.

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Sobre la presencia de Sobre la presencia de S Caulerpa racemosa Caulerpa racemosa C (Forsskal) J. Agardh (C (Forsskal) J. Agardh (C (Forsskal) J. Agardh ( aulerpales Caulerpales C , Chlorophyta Chlorophyta C ) en la costa de hlorophyta) en la costa de hlorophyta Mostaganemoise (O de Argelia) Mots clés. Algérie, Biomasse, Caulerpa racemosa, espèce invasive, Méditerranée occidentale. Palabras clave. Argelia, Biomasa, Caulerpa racemosa, especie invasora; Mediterráneo occidental.

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Anna, Ruth Thomas* Eisha Ganju Rajni Dubey Bhaskar Kumar Gupta. "Formulation And Evaluation of Griseofulvin-Loaded Invasomal Gel for Efficient Topical Delivery to Treat Dermatophytosis." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1615–23. https://doi.org/10.5281/zenodo.15205280.

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The present study aimed to formulate and evaluate griseofulvin-loaded invasomal gel for efficient topical delivery in the treatment of dermatophytosis. Griseofulvin was encapsulated in invasomes using different formulations, and their entrapment efficiency, vesicle size, and stability were assessed. Formulation F3, with a high entrapment efficiency of 72.25% and an average vesicle size of 95.58 nm, exhibited superior characteristics. The in vitro drug release studies showed that the formulation achieved 98.12% cumulative drug release at 6 hours, indicating rapid release, while formulation F3 e

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Mazurkiewicz, Kacper, and Katarzyna Masternak. "Owady inwazyjne w Polsce: Analiza zainteresowania naukowego w latach 2000-2023." Journal of Life and Medical Sciences 2 (38) 2024 (March 4, 2025): 30–40. https://doi.org/10.5281/zenodo.15526186.

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The aim of the study was to present changes in scientific interest in selected species of in-vasive insects in Poland: ladybird, western conifer seed bug, box tree moth, true bug and horsechestnut leaf miner. In our country these species do not occur naturally. Due to the lack of natu-ral factors limiting the growth of their populations, they are becoming a threat to native speciesof fauna and flora.Based on the Google Scholar database, an analysis of scientific interest in selected invasiveinsects was performed according to the concept of a narrative review. Articles, books and mono-graphs on

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Daniel, Vettori. "A Summary of the Advances in Ophthalmic Drug Delivery via Iontophoresis and Microneedles." British Journal of Pharmaceutical Research 14, no. 4 (2017): 1–7. https://doi.org/10.9734/BJPR/2016/30601.

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Drug delivery to the posterior segment of the eye is a significantly challenging task due to the underlying physiological, anatomical and metabolic constraints. Delivery of drugs through ophthalmic route is significantly hindered by multiple physiological processes including potential static and dynamic barriers. Moreover, efflux pumps expressed on ocular tissues severely restrict the intra-ocular penetration of drugs, especially into the posterior ocular tissues. However, severe ocular complications which may be sight threatening, pose an urgency for the intervention/ treatment. Currently, in

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Monowar, Alam Khalid. "A review on temperature dependent sex determination (TSD) in freshwater turtles." Journal of Biodiversity and Environmental Sciences (JBES) 24, no. 5 (2024): 159–67. https://doi.org/10.5281/zenodo.14992679.

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Temperature plays a very crucial role in turtle’s life starting from egg incubation to sex determination to day-to-day metabolism. Turtles exhibit two types of sex determination mechanism i.e. genetic sex determination (GSD) and environmental sex determination (ESD). ESD are the major mechanism observed in the turtle’s species. TSD is the most observed ESD patterns in Turtles. Three different types of TSD patterns (TSD Ia, TSD Ib and TSD II) were observed in the turtles. Most freshwater turtles exhibit TSD Ia type of TSD in which females are developed at higher temperature and male

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Trigueiro, Thiago G., Pedro N. S. Costa, Hiromi M. K. Fujishima, et al. "Invasive and Non-Invasive Ways of Measuring Intracranial Pressure and Its Importance in an Intensive Care Unit." International Journal of Research Publication and Reviews 4, no. 9 (2023): 3372–77. http://dx.doi.org/10.55248/gengpi.4.923.92523.

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Çiftçi, Ergin, Gizem Güvener, and Adem Karbuz. "Suçiçeği Seyrinde Gelişen İnvaziv Streptococcus pyogenes Enfeksiyonu." Journal of Pediatric Infection 13, no. 2 (2019): 120. http://dx.doi.org/10.5578/ced.201932.

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Kumar M Patel, Priyank, Mansiben M Patel, Chainesh N Shah, and Umesh M Upadhyay. "Optimizing Amphotericin B Invasomes: Critical Quality Attributes using Plackett Burman Design." International Journal of Science and Research (IJSR) 13, no. 8 (2024): 1323–28. http://dx.doi.org/10.21275/sr24819145533.

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