Relevant bibliographies by topics / Iode – Isotopes

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Iode – Isotopes'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 July 2024

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Journal articles on the topic "Iode – Isotopes"

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QUAIJTAAL, WILLEMIJN, STEVEN TESSEUR, TIMME H. DONDERS, PHILIPPE CLAEYS, and STEPHEN LOUWYE. "A revised and improved age model for the middle Miocene part of IODP Site U1318 (Porcupine Basin, offshore southwestern Ireland)." Geological Magazine 155, no. 5 (January 30, 2017): 1105–16. http://dx.doi.org/10.1017/s0016756816001278.

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AbstractIntegrated Ocean Drilling Program Leg 307 Site U1318 is one of the few relatively complete middle Miocene drillcores from the North Atlantic (Porcupine Basin, offshore southwestern Ireland). Using benthic foraminiferal stable carbon and oxygen isotopes, the existing age model for Site U1318 was improved. The stable isotope record displays globally recognized isotope events, used to revise the existing magnetostratigraphy-based age model. Two intervals contained misidentified magnetochrons which were corrected. The sampled interval now has a refined age of 12.75–16.60 Ma with a temporal resolution of c. 29 ka.
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Hodell, David A., and James E. T. Channell. "Mode transitions in Northern Hemisphere glaciation: co-evolution of millennial and orbital variability in Quaternary climate." Climate of the Past 12, no. 9 (September 7, 2016): 1805–28. http://dx.doi.org/10.5194/cp-12-1805-2016.

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Abstract. We present a 3.2 Myr record of stable isotopes and physical properties at IODP Site U1308 (reoccupation of DSDP Site 609) located within the ice-rafted detritus (IRD) belt of the North Atlantic. We compare the isotope and lithological proxies at Site U1308 with other North Atlantic records (e.g., sites 982, 607/U1313, and U1304) to reconstruct the history of orbital and millennial-scale climate variability during the Quaternary. The Site U1308 record documents a progressive increase in the intensity of Northern Hemisphere glacial–interglacial cycles during the late Pliocene and Quaternary, with mode transitions at ∼ 2.7, 1.5, 0.9, and 0.65 Ma. These transitions mark times of change in the growth and stability of Northern Hemisphere ice sheets. They also coincide with increases in vertical carbon isotope gradients between the intermediate and deep ocean, suggesting changes in deep carbon storage and atmospheric CO2. Orbital and millennial climate variability co-evolved during the Quaternary such that the trend towards larger and thicker ice sheets was accompanied by changes in the style, frequency, and intensity of millennial-scale variability. This co-evolution may be important for explaining the observed patterns of Quaternary climate change.
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Sissmann, Olivier, Roy Price, Marcus Elvert, Verena B. Heuer, Xavier Prieto, Christophe Monnin, Virgile Rouchon, et al. "Abiogenic formation of H2, light hydrocarbons and other short-chain organic compounds within the serpentinite mud volcanoes of the Marianna Trench." E3S Web of Conferences 98 (2019): 02011. http://dx.doi.org/10.1051/e3sconf/20199802011.

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Serpentinite-hosting mud volcanoes, located in the Marianna forearc subduction zone, were drilled during IODP Expedition 366. Recovered samples from Asùt Tesoru seamount provide new insights on the generation of organic matter in deep environments. Short-chain alcohols, volatile fatty acids and light hydrocarbons are produced within hyperalkaline pore fluids (pH 12.5) rich in H2. The stable isotope values of those species show heavy δ13C values, suggesting a formation process through Fischer-Tropsch-Type reactions. This close isotopic study brings new constraints on the reaction pathways leading to the formation of not only light hydrocarbons, but also of short-chain organic molecules. These compounds may serve as precursors of building blocks essential to life in deep oceanic settings.
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Pająk, Małgorzata. "Microwave enhanced synthesis of halogenated derivatives of L-tyrosine labeled with deuterium in aromatic ring." Journal of Radioanalytical and Nuclear Chemistry 326, no. 1 (August 28, 2020): 857–60. http://dx.doi.org/10.1007/s10967-020-07362-8.

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Abstract Three halogenated derivatives of L-tyrosine, selectively labeled with deuterium in aromatic ring, i.e., 3′-fluoro-[5′-2H]-, 3′-chloro-[5′-2H]-, and 3′-iodo-[2′,5′-2H2]-L-tyrosine, were synthesized using microwave assisted acid-catalyzed isotope exchange between 3′-fluoro-, 3′-chloro- and 3′-iodo-L-tyrosine and heavy water. The degree of deuterium incorporation was confirmed by 1H NMR spectroscopy. The spectroscopic data indicate that isotope exchange depends on the method of heating and the power of microwaves. The deuterium enrichment of 3′-fluoro-[5′-2H]- and 3′-chloro-[5′-2H]-L-tyrosine amounted to 70% and 60%, respectively, while for 3′-iodo-[2′,5′-2H2]-L-tyrosine this value was about 50% and 95% for the 2′- and 5′-position. The isotopomers were obtained in good chemical yields of 50–70%.
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De Vleeschouwer, David, Marion Peral, Marta Marchegiano, Angelina Füllberg, Niklas Meinicke, Heiko Pälike, Gerald Auer, et al. "Plio-Pleistocene Perth Basin water temperatures and Leeuwin Current dynamics (Indian Ocean) derived from oxygen and clumped-isotope paleothermometry." Climate of the Past 18, no. 5 (June 1, 2022): 1231–53. http://dx.doi.org/10.5194/cp-18-1231-2022.

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Abstract. The Pliocene sedimentary record provides a window into Earth's climate dynamics under warmer-than-present boundary conditions. However, the Pliocene cannot be considered a stable warm climate that constitutes a solid baseline for middle-of-the-road future climate projections. The increasing availability of time-continuous sedimentary archives (e.g., marine sediment cores) reveals complex temporal and spatial patterns of Pliocene ocean and climate variability on astronomical timescales. The Perth Basin is particularly interesting in that respect because it remains unclear if and how the Leeuwin Current sustained the comparably wet Pliocene climate in Western Australia, as well as how it influenced Southern Hemisphere paleoclimate variability. To constrain Leeuwin Current dynamics in time and space, this project obtained eight clumped-isotope Δ47 paleotemperatures and constructed a new orbitally resolved planktonic foraminifera (Trilobatus sacculifer) stable isotope record (δ18O) for the Plio-Pleistocene (4–2 Ma) interval of International Ocean Discovery Program (IODP) Site U1459. These new data complement an existing TEX86 record from the same site and similar planktonic isotope records from the Northern Carnarvon Basin (Ocean Drilling Program (ODP) Site 763 and IODP Site U1463). The comparison of TEX86 and Δ47 paleothermometers reveals that TEX86 likely reflects sea surface temperatures (SSTs) with a seasonal warm bias (23.8–28.9 ∘C), whereas T. sacculifer Δ47 calcification temperatures probably echo mixed-layer temperatures at the studied Site U1459 (18.9–23.2 ∘C). The isotopic δ18O gradient along a 19–29∘ S latitudinal transect, between 3.9 and 2.2 Ma, displays large variability, ranging between 0.5 ‰ and 2.0 ‰. We use the latitudinal δ18O gradient as a proxy for Leeuwin Current strength, with an inverse relationship between both. The new results challenge the interpretation that suggested a tectonic event in the Indonesian Throughflow as the cause for the rapid steepening of the isotopic gradient (0.9 ‰ to 1.5 ‰) around 3.7 Ma. The tectonic interpretation appears obsolete as it is now clear that the 3.7 Ma steepening of the isotopic gradient is intermittent, with flat latitudinal gradients (∼0.5 ‰) restored in the latest Pliocene (2.9–2.6 Ma). Still, the new analysis affirms that a combination of astronomical forcing of wind patterns and eustatic sea level controlled Leeuwin Current intensity. On secular timescales, a period of relatively weak Leeuwin Current is observed between 3.7 and 3.1 Ma. Notably, this interval is marked by cooler conditions throughout the Southern Hemisphere. In conclusion, the intensity of the Leeuwin Current and the latitudinal position of the subtropical front are both long-range effects of the same forcing: heat transport through the Indonesian Throughflow (ITF) valve and its propagation through Indian Ocean poleward heat transport. The common ITF forcing explains the observed coherence of Southern Hemisphere ocean and climate records.
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Matsuzaki, Kenji M., Hiroshi Nishi, Hiroki Hayashi, Noritoshi Suzuki, Babu R. Gyawali, Minoru Ikehara, Takuyuki Tanaka, and Reishi Takashima. "Radiolarian biostratigraphic scheme and stable oxygen isotope stratigraphy in southern Japan (IODP Expedition 315 Site C0001)." Newsletters on Stratigraphy 47, no. 1 (April 1, 2014): 107–30. http://dx.doi.org/10.1127/0078-0421/2014/0044.

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Derdau, Volker. "Radioaktive Isotope des Wasserstoffs, Kohlenstoffs und Iods." Chemie in unserer Zeit 53, no. 4 (April 17, 2019): 224–31. http://dx.doi.org/10.1002/ciuz.201800866.

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Wankel, S. D., C. Buchwald, W. Ziebis, C. B. Wenk, and M. F. Lehmann. "Nitrogen cycling in the subsurface biosphere: nitrate isotopes in porewaters underlying the oligotrophic North Atlantic." Biogeosciences Discussions 12, no. 16 (August 21, 2015): 13545–91. http://dx.doi.org/10.5194/bgd-12-13545-2015.

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Abstract. Nitrogen (N) is a key component of fundamental biomolecules. Hence, the cycling and availability of N is a central factor governing the extent of ecosystems across the Earth. In the organic-lean sediment porewaters underlying the oligotrophic ocean, where low levels of microbial activity persist despite limited organic matter delivery from overlying water, the extent and modes of nitrogen transformations have not been widely investigated. Here we use the N and oxygen (O) isotopic composition of porewater nitrate (NO3−) from a site in the oligotrophic North Atlantic (IODP) to determine the extent and magnitude of microbial nitrate production (via nitrification) and consumption (via denitrification). We find that NO3− accumulates far above bottom seawater concentrations (∼ 21 μM) throughout the sediment column (up to ∼ 50 μM) down to the oceanic basement as deep as 90 mbsf, reflecting the predominance of aerobic nitrification/remineralization within the deep marine sediments. Large changes in the δ15N and δ18O of nitrate, however, reveal variable influence of nitrate respiration across the three sites. We use an inverse porewater diffusion–reaction model, constrained by the N and O isotope systematics of nitrification and denitrification and the porewater NO3− isotopic composition, to estimate rates of nitrification and denitrification throughout the sediment column. Results indicate variability of reaction rates across and within the three boreholes that are generally consistent with the differential distribution of dissolved oxygen at this site, though not necessarily with the canonical view of how redox thresholds separate nitrate regeneration from dissimilative consumption spatially. That is, we provide isotope evidence for expanded zones of co-ocurring nitrification and denitrification. The isotope biogeochemical modeling also yielded estimates for the δ15N and δ18O of newly produced nitrate (δ15NNTR and δ18ONTR), as well as the isotope effect for denitrification (15ϵDNF), parameters with high relevance to global ocean models of N cycling. Estimated values of δ15NNTR were generally lower than previously reported δ15N values for sinking PON in this region. We suggest that these values can be related to sedimentary N-fixation and remineralization of the newly fixed organic N. Values of δ18ONTR generally ranged between −2.8 and 0.0 ‰, consistent with recent estimates based on lab cultures of nitrifying bacteria. Notably, some δ18ONTR values were elevated, suggesting incorporation of 18O-enriched dissolved oxygen during nitrification, and possibly indicating a tight coupling of NH4+ and NO2− oxidation in this metabolically sluggish environment. Our findings indicate that the production of organic matter by in situ autotrophy (e.g., nitrification, nitrogen fixation) supply a large fraction of the biomass and organic substrate for heterotrophy in these sediments, supplementing the small organic matter pool derived from the overlying euphotic zone. This work sheds new light on an active nitrogen cycle operating, despite exceedingly low carbon inputs, in the deep sedimentary biosphere.
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Wankel, S. D., C. Buchwald, W. Ziebis, C. B. Wenk, and M. F. Lehmann. "Nitrogen cycling in the deep sedimentary biosphere: nitrate isotopes in porewaters underlying the oligotrophic North Atlantic." Biogeosciences 12, no. 24 (December 21, 2015): 7483–502. http://dx.doi.org/10.5194/bg-12-7483-2015.

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Abstract. Nitrogen (N) is a key component of fundamental biomolecules. Hence, its cycling and availability are central factors governing the extent of ecosystems across the Earth. In the organic-lean sediment porewaters underlying the oligotrophic ocean, where low levels of microbial activity persist despite limited organic matter delivery from overlying water, the extent and modes of nitrogen transformations have not been widely investigated. Here we use the N and oxygen (O) isotopic composition of porewater nitrate (NO3−) from a site in the oligotrophic North Atlantic (Integrated Ocean Drilling Program – IODP) to determine the extent and magnitude of microbial nitrate production (via nitrification) and consumption (via denitrification). We find that NO3- accumulates far above bottom seawater concentrations (~ 21 μM) throughout the sediment column (up to ~ 50 μM) down to the oceanic basement as deep as 90 m b.s.f. (below sea floor), reflecting the predominance of aerobic nitrification/remineralization within the deep marine sediments. Large changes in the δ15N and δ18O of nitrate, however, reveal variable influence of nitrate respiration across the three sites. We use an inverse porewater diffusion–reaction model, constrained by the N and O isotope systematics of nitrification and denitrification and the porewater NO3- isotopic composition, to estimate rates of nitrification and denitrification throughout the sediment column. Results indicate variability of reaction rates across and within the three boreholes that are generally consistent with the differential distribution of dissolved oxygen at this site, though not necessarily with the canonical view of how redox thresholds separate nitrate regeneration from dissimilative consumption spatially. That is, we provide stable isotopic evidence for expanded zones of co-occurring nitrification and denitrification. The isotope biogeochemical modeling also yielded estimates for the δ15N and δ18O of newly produced nitrate (δ15NNTR (NTR, referring to nitrification) and δ18ONTR), as well as the isotope effect for denitrification (15ϵDNF) (DNF, referring to denitrification), parameters with high relevance to global ocean models of N cycling. Estimated values of δ15NNTR were generally lower than previously reported δ15N values for sinking particulate organic nitrogen in this region. We suggest that these values may be, in part, related to sedimentary N2 fixation and remineralization of the newly fixed organic N. Values of δ18ONTR generally ranged between −2.8 and 0.0 ‰, consistent with recent estimates based on lab cultures of nitrifying bacteria. Notably, some δ18ONTR values were elevated, suggesting incorporation of 18O-enriched dissolved oxygen during nitrification, and possibly indicating a tight coupling of NH4+ and NO2− oxidation in this metabolically sluggish environment. Our findings indicate that the production of organic matter by in situ autotrophy (e.g., nitrification, nitrogen fixation) supplies a large fraction of the biomass and organic substrate for heterotrophy in these sediments, supplementing the small organic-matter pool derived from the overlying euphotic zone. This work sheds new light on an active nitrogen cycle operating, despite exceedingly low carbon inputs, in the deep sedimentary biosphere.
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Bolla, Ratna Sekhar, Narasimha Murthy Gandikota, and Ivaturi Venkata Kasi Viswanath. "Synthesis of Deuterium Labeled 5, 5-Dimethyl-3-(α, α, α-trifluoro-4-nitro-m-tolyl) Hydantoin." Current Radiopharmaceuticals 12, no. 1 (March 4, 2019): 82–87. http://dx.doi.org/10.2174/1874471012666181130162731.

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Objective: Stable and non-radioactive isotope labeled compounds gained significance in recent drug discovery and other various applications such as bio-analytical studies. The modern bioanalytical techniques can study the adverse therapeutic effects of drugs by comparing isotopically labeled internal standards. A well-designed labeled compound can provide high-quality information about the identity and quantification of drug-related compounds in biological samples. This information can be very useful at key decision points in drug development. In this study, we tried to synthesize Nilutamide- d6 which can be useful to study the adverse effects of Nilutamide, and based on these can modify or widen the new drug derivatives. Nilutamide is a nonsteroidal antiandrogen which is used in the treatment of prostate cancer. The aim of this study was to develop a synthetic approach to prepare deuterium labeled [2H6]-5, 5-dimethylimidazolidine-2, 4-dione and [2H6]-nilutamide. Methods: Since nilutamide is a derivative of hydantoin, it involves the synthesis of Dimethylhydantoin via Bucherer-Bergs hydantoin synthesis, followed by oxidative N-arylation with 4-iodo-1-nitro-2- (trifluoromethyl) benzene. Conclusion: We successfully synthesized [2H6]-nilutamide and [2H6]-dimethylhydantoin with good isotopic purity, measured to be of adequate quality for use as internal standards in bio-analytical studies. A brief mechanistic study of Bucherer-Bergs hydantoin reaction was carried and the reason for possible H/D exchange was explained.
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Dissertations / Theses on the topic "Iode – Isotopes"

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Berdal, Marion. "Exploration de nouvelles voies de radiomarquage avec l’astate-211 sous forme nucléophile : application à la préparation de radioimmunoconjugués pour la thérapie alpha vectorisée des cancers." Thesis, Nantes, 2020. http://www.theses.fr/2020NANT1021.

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L’astate-211 est un radionucléide prometteur pour la thérapie alpha vectorisée des cancers. Cependant, les méthodes actuelles de radiomarquage d’anticorps avec ce radiohalogène présentent de nombreuses limites telles que des rendements non-optimaux ou l’utilisation de précurseurs toxiques, ce qui complique son transfert en clinique. Afin de proposer des alternatives plus viables, l’exploration de nouvelles classes de précurseurs permettant le radiomarquage avec l’astate-211 et l’iode-125 sous forme nucléophile a été menée. Dans un premier temps, la synthèse de composés modèles pour chacune de ces classes et leur comparaison en termes d’efficacité a été réalisée afin d’identifier les plus adaptées pour le radiomarquage avec ces deux radionucléides. Dans une deuxième partie, la faisabilité d’un radiomarquage d’anticorps à l’astate-211 et à l’iode-125 en une seule étape, utilisant les acides arylboroniques, a été investigué. Dans un premier temps, l’étude de réactivité sur un composé modèle simple a été effectuée afin d’identifier des conditions efficaces en milieu aqueux et à basse température avant de transférer cette approche à un anticorps anti- CD138 d’intérêt pour le ciblage du myélome multiple. Le nouveau procédé ainsi développé surpasse les autres méthodes rapportées dans la littérature et a été validé par des études précliniques de biodistributions. Cette nouvelle méthode de radiomarquage devrait faciliter le passage de l’astate-211 en clinique et permettre le développement d’outils théranostiques basés sur la paire astate/iode
Astatine-211 is a promising radionuclide for targeted alpha therapy of cancers. However, current approaches to bind this radiohalogen to an antibody exhibit limitations such as suboptimal radiochemical yields or the use of toxic precursors, which complicates its clinical transfer. In order to find better alternatives, we explored new classes of precursors, which allow the radiolabelling with astatine-211 and iodine-125 in their nucleophilic form. First, the synthesis of model compounds for each class and the comparison of their efficiency were performed to identify the most promising ones for the radiolabelling with both radionuclides. In a second part, the feasibility of the one-step radiolabelling of antibodies with astatine-211 and iodine-125 using arylboronic acids has been investigated. First, the study on a model compound was conducted in order to identify efficient conditions in aqueous medium and at low temperature before transfering this approach to an anti-CD138 antibody of interest for targeting multiple myeloma. The new process developped outperforms others methods reported in the litterature and has been validated in preclinical biodistribution studies. This new radiolabelling method will ease the clinical transfer of astatine-211 as well as the development of theranostic tools based on the astatine/iodine pair
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Anizan, Nadège. "Imagerie quantitative à l'iode-124 en tomographie par émission de positons du petit animal." Nantes, 2010. https://archive.bu.univ-nantes.fr/pollux/show/show?id=c64acd83-1c60-46d1-8815-0c6a3002c879.

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L'imagerie quantitative TEP à l'iode-124 nécessite l'optimisation des paramètres d'acquisition, et des corrections appropriées à la complexité du spectre d’émission de cet isotope. Une première approche expérimentale établit les performances de la caméra TEP Inveon de Siemens dédiée au petit animal et met en évidence les conséquences des propriétés physiques de l’iode-124 sur les images. Pour adapter ou développer des méthodes de corrections des divers biais démontrés expérimentalement, la caméra TEP Inveon a été modélisée avec la plateforme de simulation Monte-Carlo GATE. La validation du modèle a été réalisée par la comparaison des performances expérimentales et simulées, obtenues pour le fluor-18 et l'iode-124. La simulation d’objets tests placés dans le modèle de la camera Inveon a permis de déterminer la méthode de correction la plus adaptée aux photons simples émis par l'iode-124. L'ensemble des optimisations obtenues sur des objets tests de formes géométriques simples a ensuite été testé expérimentalement dans le cas du petit animal. Les résultats montrent que certains des paramètres optimisés sur les objets tests n'ont pas d'influence sur la quantification de l'activité dans le cas réaliste d’une souris injectée à l'iode-124. Ce travail de thèse démontre la possibilité d'une quantification par imagerie TEP de la distribution d'anticorps monoclonaux marqués à l'iode-124 injectés dans une souris
Iodine-124 PET quantitative imaging requires the optimisation of acquisition parameters and of corrections adapted to the complex nature of the emission spectrum of that isotope. A first experimental approach establishes the performance of the Inveon, Siemens PET system dedicated to small animal and highlights the consequences of iodine-124 physical properties on images. To adapt or develop correction methods for various biases demonstrated experimentally, the PET camera Inveon was modelled with the Monte-Carlo simulation platform, GATE. Model validation was conducted by comparing simulated and experimental performances obtained for fluorine-18 and iodine-124. The simulation of test object placed in the Inveon system model determined the correction method most suitable for singles photons emitted by iodine-124. All optimisations performed on test objects of simple geometric shapes were tested in the case of small animal. The results show that some parameters optimised on the test objects did not influence the quantification of activity in the realistic case of a mouse injected with iodine-124. This thesis demonstrates the possibility of quantification by PET imaging of the distribution of monoclonal antibodies labelled with iodine-124 injected into a mouse
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Marie, Pierre-Yves. "Évaluation de la viabilité myocardique par un acide gras beta-méthyle marque par l'iode-123 : étude réalisée chez l'homme et sur un modèle de cœur isolé perfusé de lapin." Nancy 1, 1996. http://www.theses.fr/1996NAN10373.

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Gaillard, Clotilde. "Étude de la migration thermique des produits de fission molybdène, technétium et iode dans les apatites." Lyon 1, 2000. http://www.theses.fr/2000LYO10253.

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Dans l'optique d'un stockage en site géologique des déchets nucléaires à vie longue, les apatites sont envisagées, d'une part comme matrice de confinement d'actinides ou de produits de fission à vie longue, et d'autre part, comme matériaux incorporés dans les barrières ouvragées. Nos travaux consistent à étudier la migration dans les apatites des produits de fission en fonction de la température. . Nous avons choisi d'étudier l'iode 129, de période 16 millions d'années et le technétium 99, de période 210000 ans. Le but est d'obtenir une modélisation du comportement de ces éléments afin d'extrapoler leur devenir sur une longue période. L'apatite étudiée est de l'hydroxyapatite de synthèse de composition chimique connue Ca10(PO4)6(OH)2. Afin de limiter les problèmes de radioprotection, nous avons étudié le comportement du technétium via le rhénium, son homologue chimique, et le molybdène, de masse proche de celle du technétium. Le couplage implantation ionique - RBS nous a permis de mettre en évidence une volatilisation de ces éléments lors de recuits sous air. Nous avons alors entrepris des études de caractérisation chimique du molybdène et du rhénium par XPS et XANES. Nous avons mis en évidence une oxydation de ces éléments, entraînant la formation d'oxydes volatils. Dans le cas de l'iode, nous avons conjointement mené des expériences avec de l'iode 131 radioactif et de l'iode stable, montrant une diffusion de cet élément dans les joints de grains du matériaux.
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Perret, Pascale. "Études biologiques de nouveaux analogues iodés du glucose et validation du 6-deoxy-6-iodo-d-glucose (6DIG) comme traceur du transport du glucose in vivo." Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE19006.

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Noguere, Gilles. "Measurements and analysis of the iodine 127 and 129 neutron total and capture cross sections from 0,5eV to 100keV." Université Louis Pasteur (Strasbourg) (1971-2008), 2003. https://publication-theses.unistra.fr/public/theses_doctorat/2003/NOGUERE_Gilles_2003.pdf.

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Agostini, Denis. "La scintigraphie cardiaque à la I-123 métaiodobenzylguanidine (MIBG) : méthode d'évaluation des réserves adrénergiques dans l'insuffisance cardiaque congestive, implications physiopathologiques et thérapeutiques." Caen, 1991. http://www.theses.fr/1991CAEN3071.

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Delpon, Grégory. "Optimisation des protocoles d'imagerie quantitative planaire pour la dosimétrie lors des études cliniques de radioimmunothérapie à l'iode 131." Toulouse 3, 2002. http://www.theses.fr/2002TOU30165.

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Escoula, Brigitte. "Conception moléculaire et associations en solution : synthèse modulaire d'amphiphilesNouvelles méthodes de marquage à l'iode et au fluor de molécules à activité dopaminergique potentielle." Toulouse, INPT, 1988. http://www.theses.fr/1988INPT016G.

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Trincal, Julien. "Modélisation du comportement de l’iode dans l’atmosphère." Thesis, Lille 1, 2015. http://www.theses.fr/2015LIL10121/document.

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Abstract:
Lors d'un accident grave survenant à une installation nucléaire, les conséquences radiologiques sont liées au transport et au dépôt des radionucléides relâchés dans l’environnement. Suite à l'accident de Fukushima, des écarts significatifs entre mesures et prévisions ont été observés pour l'iode. Ces derniers pourraient notamment s'expliquer par la non prise en compte de la chimie lors du transport dans les codes de dispersion mis en œuvre. Afin de vérifier cette hypothèse, un mécanisme réactionnel de l'iode dans l’atmosphère a été développé à partir d’une revue critique des données de la littérature et des simulations 0D et 3D, à l’aide des outils de calcul ASTEC et Polair3D, ont été réalisées. Les résultats obtenus ont mis en évidence une transformation partielle et rapide de l’iode gazeux (I2 et CH3I) émis. L'influence sur la spéciation de l’iode de paramètres tels que les conditions de pollution (O3, NOx, COV), de photolyse ainsi que la quantité d'iode relâchée est étudiée. L'iode se retrouve rapidement sous forme d'oxydes (IxOy, INOx) et d'iodocarbones. Des points d’amélioration notables concernant le mécanisme réactionnel (absence de données fondamentales qui restent à déterminer et ajout du couplage chimie-aérosol) restent à apporter pour conclure avec certitude sur les formes d’iode radioactif susceptibles d’être présentes dans l’atmosphère
During a severe accident occuring to a nuclear facility, the radiological consequences are related to the transport and deposition of radionuclides released into the environment. Following the Fukushima accident, significant differences between measurements and simulations were observed for iodine. These could notably be explained by the absence of any iodine chemistry during the transport in the dispersion codes used. To investigate this hypothesis, a reactional mechanism of iodine in the atmosphere has been developed from a critical review of the literature data and 0D and 3D simulations has been performed using the ASTEC and Polair3D simulation tools.The results obtained showed a partial and fast transformation of the released gaseous iodine (I2 and CH3I). The influence of parameters on the iodine speciation such as the pollutant conditions (O3, NOx, COV), photolysis and the amount of iodine is discussed.Iodine turns quickly into oxide forms (IxOy, INOx) and iodocarbons. Significant improvements regarding the reactional mechanism (determination of fundamental data, coupling chemistry-aerosol) remain to be done before coming up with a firm conclusion on the radioactive iodine species present in the atmosphere
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Books on the topic "Iode – Isotopes"

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Styro, B. I. Izotopy ioda i radiat͡s︡ionnai͡a︡ bezopasnostʹ. Sankt-Peterburg: Gidrometeoizdat, 1992.

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Book chapters on the topic "Iode – Isotopes"

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Wolf, H., A. Pethe, M. Schramm, K. H. Bohuslavizki, W. Brenner, M. Clausen, H. J. Otto, and E. Henze. "Experimental Studies of I-123-Labelled Iodo-Doxorubicin." In Radioactive Isotopes in Clinical Medicine and Research, 351–55. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7340-6_49.

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Angelberger, P., T. Brücke, H. Kvaternik, and T. Wanek. "Radiopharmaceutical Development of 123I-(+)-3-Iodo-MK 801 for Nmda-Receptor Scintigraphy." In Radioactive Isotopes in Clinical Medicine and Research, 321–25. Basel: Birkhäuser Basel, 1997. http://dx.doi.org/10.1007/978-3-0348-7772-5_48.

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Bohuslavizki, K. H., D. Lennert, H. Wolf, J. U. Eberhardt, W. Brenner, M. Schramm, M. Clausen, M. Dietel, and E. Henze. "Different Uptake of Iodo-Doxorubicin Labelled with I-123 in Tumour Cells of Gastric Carcinoma Being Sensitive and Resistant to Anthracyclines." In Radioactive Isotopes in Clinical Medicine and Research, 293–96. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7340-6_41.

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Bohuslavizki, K. H., K. Röhe, H. Wolf, W. Brenner, J. U. Eberhardt, M. Schramm, M. Clausen, M. Dietel, and E. Henze. "Uptake of 4-Iodo-Doxorubicin Labelled with I-123 and Tc-99m in Tumour Cells of Gastric Carcinoma and Suprarenal Gland Carcinoma." In Radioactive Isotopes in Clinical Medicine and Research, 405–8. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7340-6_58.

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Das, Supriyo Kumar, Ujan Karmakar, Arunabha Dey, Sandip Agrahari, and Alf Ekblad. "Carbon Stable Isotope Source Signature of Bulk Organic Matter in Middle Bengal Fan Sediment Collected During IODP Expedition 354." In Dynamics of the Earth System: Evolution, Processes and Interactions, 91–99. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40659-2_5.

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Smith, M. E., E. V. Glick, S. Lodestro, and H. Rashid. "Data report: oxygen isotopes and foraminifer abundance record for the last glacial–interglacial cycle and marine isotope Stage 6 at IODP Site U1313." In Proceedings of the IODP. Integrated Ocean Drilling Program, 2013. http://dx.doi.org/10.2204/iodp.proc.303306.216.2013.

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Li, Q., F. Zheng, X. Cheng, and R. Xiang. "Data report: planktonic foraminifer stable isotope results from IODP Hole U1322B." In Proceedings of the IODP. Integrated Ocean Drilling Program, 2008. http://dx.doi.org/10.2204/iodp.proc.308.201.2008.

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Takashima, C., A. Kano, and X. Li. "Data report: carbon and oxygen isotopes of bulk sediments from the off-mound site, Hole U1318B." In Proceedings of the IODP. Integrated Ocean Drilling Program, 2009. http://dx.doi.org/10.2204/iodp.proc.307.202.2009.

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Toki, T., K. Higa, and R. Shinjo. "Data report: boron isotope ratios in interstitial waters from Sites C0021 and C0022." In Proceedings of the IODP. Integrated Ocean Drilling Program, 2015. http://dx.doi.org/10.2204/iodp.proc.338.203.2015.

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Choi, J., J. H. Kim, G. Y. Kim, and S. W. Chang. "Data report: gas isotope and conversion ratio of headspace and void gas, IODP Expedition 344." In Proceedings of the IODP. Integrated Ocean Drilling Program, 2016. http://dx.doi.org/10.2204/iodp.proc.344.203.2016.

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Conference papers on the topic "Iode – Isotopes"

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Cao, Cheng, Yuanfeng Cai, Weiqiang Li, Tianyu Chen, and Jun Chen. "K isotope composition of IODP 376 drilling cores: implications for hydrothermal alteration in submarine arc volcanoes." In Goldschmidt2022. France: European Association of Geochemistry, 2022. http://dx.doi.org/10.46427/gold2022.10704.

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Shaikh Miyasaheb, Juzer Idris, and Dr Sambuddha Misra. "Constraining the Seawater Mass and Isotope Budget of Lithium: Results from IODP Leg 339 and Leg 379." In Goldschmidt2023. France: European Association of Geochemistry, 2023. http://dx.doi.org/10.7185/gold2023.14636.

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Hu, Lingzhi, Fang Huang, Yuhan Qi, and Jinting Kang. "Ca isotope composition of the altered oceanic crust from the IODP Site 1256 at the East Pacific Rise." In Goldschmidt2021. France: European Association of Geochemistry, 2021. http://dx.doi.org/10.7185/gold2021.4192.

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Galy, Albert. "Triple Oxygen and Hydrogen Isotopic Variations of Pore Waters from the Middle Bengal Fran (IODP Exp. 354)." In Goldschmidt2020. Geochemical Society, 2020. http://dx.doi.org/10.46427/gold2020.780.

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Corsello, Alexander, Adriane Lam, Catherine Beck, and Bruce Wegter. "ISOTOPE PALEOECOLOGY OF GLOBOQUADRINA DEHISCENS ACROSS THE MIOCENE CLIMATE OPTIMUM IN THE SOUTHWEST PACIFIC, IODP SITE U1510." In GSA Connects 2023 Meeting in Pittsburgh, Pennsylvania. Geological Society of America, 2023. http://dx.doi.org/10.1130/abs/2023am-390298.

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Pring, Oliver, Lucy McGee, Julie Prytulak, and Mark Reagan. "Copper isotope analysis of fore-arc basalt and boninite glasses from the Bonin fore-arc system, IODP Expedition 352." In Goldschmidt2023. France: European Association of Geochemistry, 2023. http://dx.doi.org/10.7185/gold2023.16351.

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Andronikides, Alex, Ashley Iervolino, and Stephen F. Pekar. "LATE MIOCENE (10.4-7.8 MA) PALEOCEANOGRAPHIC CHANGES ON THE CONTINENT OF ZEALANDIA USING STABLE ISOTOPE RECORDS FROM IODP SITE U1508." In 54th Annual GSA Northeastern Section Meeting - 2019. Geological Society of America, 2019. http://dx.doi.org/10.1130/abs/2019ne-328000.

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Mindrup, Quinton, Ryan Mathur, Pamela Kempton, A. Evans, Rosalind M. Coggon, Damon A. H. Teagle, Julia S. Reece, Jason Sylvan, Trevor J. Williams, and Emily Racz Estes. "IMPACT OF SEAWATER ALTERATION ON CU ISOTOPE COMPOSITION OF OCEANIC BASALTS ALONG THE SOUTH ATLANTIC TRANSECT: IODP EXP 390/393." In GSA Connects 2023 Meeting in Pittsburgh, Pennsylvania. Geological Society of America, 2023. http://dx.doi.org/10.1130/abs/2023am-392408.

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Moore, Evan, and Peter Swart. "Recrystallization within Warm-Water Drift Deposits and Cool-Water Carbonate Ramps: Clumped and Sulfur Isotopes from ODP Leg 182 and IODP Leg 359." In Goldschmidt2021. France: European Association of Geochemistry, 2021. http://dx.doi.org/10.7185/gold2021.6381.

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Böttcher, Michael E., Hans-J. Brumsack, Iris Schmiedinger, and Tracy M. Quan. "Microbial Activity, Mineral Authigenesis and Fluid Mixing in Deep Interstitial Fluids off South-Western Australia (IODP Leg 369): A Multi-Isotope Approach." In Goldschmidt2020. Geochemical Society, 2020. http://dx.doi.org/10.46427/gold2020.230.

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