Academic literature on the topic 'Iodine radioisotopes; Radioactive; Thyroglobulin'
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Journal articles on the topic "Iodine radioisotopes; Radioactive; Thyroglobulin"
ITO, Tomiyasu, Norio NOGAWA, Kunio OOHASHI, Asao NAKAMURA, and Naotake MORIKAWA. "Radioactive iodine absorbing properties of tetrathiafulvalene." RADIOISOTOPES 38, no. 5 (1989): 237–43. http://dx.doi.org/10.3769/radioisotopes.38.5_237.
Full textMatthews, T. J., E. Chua, A. Gargya, J. Clark, K. Gao, and M. Elliott. "Elevated serum thyroglobulin levels at the time of ablative radioactive iodine therapy indicate a worse prognosis in thyroid cancer: an Australian retrospective cohort study." Journal of Laryngology & Otology 130, S4 (July 2016): S50—S53. http://dx.doi.org/10.1017/s0022215116008331.
Full textGargya, Ash, and Elizabeth Chua. "Focal Bronchiectasis Causing Abnormal Pulmonary Radioiodine Uptake in a Patient with Well-Differentiated Papillary Thyroid Carcinoma." Case Reports in Endocrinology 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/452758.
Full textJiang, Yuyan, Jiahui Jin, Jingzheng Fan, Chao Huang, Qiang Jia, Jian Tan, Xianghui He, et al. "Urinary iodine concentration and radioactive iodine therapeutic response in patients with differentiated thyroid cancer." Biomarkers in Medicine 15, no. 11 (August 2021): 879–90. http://dx.doi.org/10.2217/bmm-2020-0745.
Full textWang, Chen, Xin Zhang, Hui Li, Xin Li, and Yansong Lin. "Quantitative thyroglobulin response to radioactive iodine treatment in predicting radioactive iodine-refractory thyroid cancer with pulmonary metastasis." PLOS ONE 12, no. 7 (July 13, 2017): e0179664. http://dx.doi.org/10.1371/journal.pone.0179664.
Full textSHIBUYA, Koichi, Kiyonori YAMAOKA, Tomohiro NAGAMATSU, Katsumi HANAMOTO, Shoji KAWASAKI, and Yoshio HIRAKI. "Simple and Easy Method for Measurement of Airborne Radioactive Iodine(125I)." RADIOISOTOPES 51, no. 2 (2002): 66–70. http://dx.doi.org/10.3769/radioisotopes.51.66.
Full textKwong, Norra, Ellen Marqusee, Michael S. Gordon, P. Reed Larsen, Jeffrey R. Garber, Matthew I. Kim, and Erik K. Alexander. "Long-term, treatment-free survival in select patients with distant metastatic papillary thyroid cancer." Endocrine Connections 3, no. 4 (December 2014): 207–14. http://dx.doi.org/10.1530/ec-14-0097.
Full textCarhill, Aubrey A., and Rena Vassilopoulou-Sellin. "Durable Effect of Radioactive Iodine in a Patient with Metastatic Follicular Thyroid Carcinoma." Case Reports in Endocrinology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/231912.
Full textSlonimsky, Einat, and Mark Tulchinsky. "Radiotheragnostics Paradigm for Radioactive Iodine (Iodide) Management of Differentiated Thyroid Cancer." Current Pharmaceutical Design 26, no. 31 (September 17, 2020): 3812–27. http://dx.doi.org/10.2174/1381612826666200605121054.
Full textRothenberg, Stephen M., David G. McFadden, Edwin Palmer, Gilbert H. Daniels, and Lori J. Wirth. "Re-differentiation of radioiodine-refractory BRAF V600E-mutant thyroid carcinoma with dabrafenib: A pilot study." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 6025. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.6025.
Full textDissertations / Theses on the topic "Iodine radioisotopes; Radioactive; Thyroglobulin"
Adil-Smith, Iran. "Structural analysis of thyroid hormones by EXAFS and molecular simulation : biological effects of '1'2'5I." Thesis, Brunel University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362488.
Full textGUIMARÃES, Giulliana Nóbrega. "Fatores associados à persistência do carcinoma diferenciado de tireoide um ano após radioiodoterapia." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/16677.
Full textMade available in DSpace on 2016-04-19T11:21:33Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) DISSERTAÇAO-GIULLIANA_NOBREGA.pdf: 1803238 bytes, checksum: 3e84c45ed9de31b5cd10607f9f195dca (MD5) Previous issue date: 2015-06-15
CNPq
INTRODUÇÃO: O carcinoma diferenciado de tireoide (CDT) é avaliado e tratado de acordo com fatores prognósticos. Embora tenha um bom prognóstico, 14% dos pacientes considerados como de baixo risco de recorrência podem apresentar doença persistente mesmo com tratamento adequado. Por isso, estudos têm sido realizados no intuito de encontrar outros possíveis preditores de persistência do CDT. OBJETIVO: Avaliar que fatores clínicos, laboratoriais e anatomopatológicos estão associados à persistência do CDT um ano após radioiodoterapia (RIT). METODOLOGIA: Foi realizada uma revisão de prontuários, na qual foram incluídos 375 pacientes portadores de CDT. Foram coletados dos registros os dados clínicos (gênero e idade), resultados de dosagens de hormônio tireoestimulante (TSH), tireoglobulina (Tg) e anticorpo anti-tireoglobulina (AATg) antes e um ano após RIT, resultados de varredura de corpo inteiro (PCI) após dose ablativa de radioiodo (131I) e um ano após tratamento inicial, além de laudos dos exames histopatológicos. A partir dos dados obtidos, foi realizada análise bivariada e as variáveis que apresentaram significância inferior a 20,0% (p < 0,20) foram submetidas à análise multivariada através do modelo de regressão de Poisson. Para se chegar a um valor de Tg estimulada (TgE) capaz de predizer os pacientes que teriam maior chance de persistência de doença, foi realizada uma curva ROC. RESULTADOS: Observou-se associação significativa entre persistência de doença e idade inferior a 45 anos (p=0,001), multifocalidade (p=0.008) e tamanho tumoral entre 2 a 4 cm (p=0,002). Além disso, verificou-se associação significativa entre da TgE e persistência do CDT (p<0,001). O ponto de corte de TgE pré-dose com maior sensibilidade e especificidade para prever persistência de doença foi de 7,4 ng/mL. Utilizando este valor encontramos um valor preditivo negativo (VPN) de 87,5%. CONCLUSÃO: Neste estudo encontramos uma forte associação entre persistência do CDT e faixa etária, tamanho tumoral, multifocalidade e Tg estimulada pré-ablação. A Tg estimulada pré-ablação mostrou-se um valioso preditor de persistência de CDT um ano após RIT. Valores de 7,4 ng/mL ou mais mostraram maior sensibilidade e especificidade para prever este desfecho.
BACKGROUND: Differentiated thyroid carcinoma (CDT) is evaluated and treated according to prognostic factors. Although it has a good prognosis, 14% of the patients which are considered at low risk of recurrence, might have persistent disease despite suitable treatment. Hence, studies have been realized in order to find other possible prognostic predictors for CDT persistence. OBJECTIVE: Assess which clinical, laboratory and pathological factors are associated with persistence of CDT one year after radioiodine therapy (RIT). METHODS: It was performed a chart review, in which was included 375 patients with CDT. Were collected clinical data (age and sex), results of thyroid-stimulating hormone (TSH), thyroglobulin (Tg) and antithyroglobulin antibody (AATg) before and one year after RIT, whole body scan (PCI) results after ablative dose of 131I and one year later and, also histopathological exam reports. From these data, was performed a bivariate analysis and the variables that were significant lower than 20.0% (p <0.20) were submitted to multivariate analysis using Poisson regression model. To achieve a stimulated Tg (TgE) value able to predict which patients would have a greater chance of persistent disease, a ROC curve was performed. RESULTS: A significant association was found between persistence of disease and age less than 45 years (p = 0.001), multifocality (p = 0.008) and tumor size between 2-4 cm (p = 0.002). In addition, there was a significant association between TgE and persistence of CDT (p <0.001). The pre-ablation TgE cutoff with greater sensitivity and specificity in predicting persistence of disease was 7.4 ng / mL. Using this value, we found a negative predictive value (VPN) of 87.5%. CONCLUSION: We found a significant association between persistent CDT and age, tumor size, multifocality and pre-ablation TgE in this study. TgE pre-ablation was shown to be a valuable predictor of persistence CDT one year after RIT. Values of 7.4 ng / ml or more showed greater sensitivity and specificity to predict this outcome.
Fernandes, Roberta Possato. "Quantificação do RNAm de tireoglobulina em sangue periférico de pacientes com câncer diferenciado de tireóide: acompanhamento a longo prazo." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-15042009-154717/.
Full textThe differentiated thyroid carcinoma (DTC) encloses 95% of all thyroid malignant disease. In USA, it increased 2,4 times in recent years (1973- 2002). The treatment includes total thyroidectomy, ablation with radioiodine (RAI) followed by TSH suppression with L-Thyroxine. The cancer recurrence occurs in 20% of the cases. Periodic evaluation through imaging examinations and serum thyroglobulin (TG) measurements by imunoassays method is recommended for careful follow-up of these patients. The anti-TG antibodies prevalence is 15-25% and would impair, partially, the serum TG use as a tumor marker. An alternative method to identify the recurrence of the tumor is the thyroid cells detection in peripheral blood, through the TG messenger RNA quantification (mRNA-TG) by real time RT-PCR. This new methodology increases the sensitivity detection for this molecule. The objective of this study was to verify the mRNA-TG peripheral blood quantification significance, as a complementary diagnostic method in the long term follow up of patients with DTC. Fourty five blood samples from patients with DTC have been collected before and 24, 48, 72 hours, 7 days, 1, 3, 6, 9 months, 1, 2, 4, 5, 6 and 7 years after the ablation therapy. Extensive technique standardization for mRNA-TG measurements was carried out to exclude methodological interventions and two housekeeping genes (GAPDH and HPRT1) were used to calculate the mRNA-TG concentrations. Concomitantly, serum TG measurements, hormonal profile and antibodies anti-TG assays were performed. The whole body scan was performed 7 days after RAI ablation to determine the stage of the disease. It was not possible to establish a cut-point value for mRNA-TG. The mRNA-TG did not differentiated the clinical stage of the disease in the long term follow-up and neither in the presence of anti-TG antibodies and TSH30ng/mL. Serum TG was able to differentiate the clinical stage of the patients during the follow-up. In conclusion mRNA-TG is not a good marker for the DCT recurrence, even when technical standardization, long term evaluation and the presence of antibodies anti-TG were considered. Thus it could not be used as a complementary diagnostic method in the DTC patients follow-up. This study confirmed the high sensivity of the real time RT-PCR whereas with very low specificity, consequently is unviable to be used in the DTC patients follow-up
Harvey, Richard Paul. "Uncertainty of inhalation dose coefficients for representative physical and chemical forms of ¹³¹I." 2002. http://books.google.com/books?id=MldYAAAAMAAJ.
Full textHay, Tristan Ryan. "Medical radionuclides and their impurities in wastewater." Thesis, 2012. http://hdl.handle.net/1957/29342.
Full textGraduation date: 2012
Access restricted to the OSU Community at author's request from May 24, 2012 - May 24, 2014
Books on the topic "Iodine radioisotopes; Radioactive; Thyroglobulin"
Sheppard, S. C. Importance of chemical speciation of iodine in relation to dose estimates from 129I. Pinawa, Man: Whiteshell Laboratories, Environmental Science Branch, 1996.
Find full textStyro, B. I. Izotopy ioda i radiat͡s︡ionnai͡a︡ bezopasnostʹ. Sankt-Peterburg: Gidrometeoizdat, 1992.
Find full textInstitute of Medicine (U.S.). Committee on Thyroid Screening Related to I-131 Exposure. and National Research Council (U.S.). Committee on Exposure of the American People to I-131 from the Nevada Atomic Bomb Tests., eds. Exposure of the American people to Iodine-131 from Nevada nuclear-bomb tests: Review of the National Cancer Institute report and public health implications. Washington, D.C: National Academy Press, 1999.
Find full text(US), National Research Council. Exposure of the American People to Iodine-131 from Nevada Nuclear-Bomb Tests: Review of the National Cancer Institute Report and Public Health Implications. National Academies Press, 1999.
Find full textBook chapters on the topic "Iodine radioisotopes; Radioactive; Thyroglobulin"
Alzahrani, Ali S., Omalkhaire Alshaikh, Sameerah Al-Shehri, and Rafif Farhat. "Radioactive Iodine (I-131) Therapy for Thyroglobulin Positive, Scan Negative Differentiated Thyroid Cancer." In The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego, P1–564—P1–564. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part1.p12.p1-564.
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