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Journal articles on the topic 'Iodine radioisotopes; Radioactive; Thyroglobulin'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

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1

ITO, Tomiyasu, Norio NOGAWA, Kunio OOHASHI, Asao NAKAMURA, and Naotake MORIKAWA. "Radioactive iodine absorbing properties of tetrathiafulvalene." RADIOISOTOPES 38, no. 5 (1989): 237–43. http://dx.doi.org/10.3769/radioisotopes.38.5_237.

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2

Matthews, T. J., E. Chua, A. Gargya, J. Clark, K. Gao, and M. Elliott. "Elevated serum thyroglobulin levels at the time of ablative radioactive iodine therapy indicate a worse prognosis in thyroid cancer: an Australian retrospective cohort study." Journal of Laryngology & Otology 130, S4 (2016): S50—S53. http://dx.doi.org/10.1017/s0022215116008331.

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AbstractBackground:Serum thyroglobulin is used as a surrogate marker for well-differentiated thyroid carcinoma recurrence. This study investigates whether thyroglobulin measured at the time of ablative radioactive iodine therapy predicts disease-free survival.Methods:A retrospective review was conducted of patients with well-differentiated thyroid carcinoma presenting from 1989 to 2010 at the Royal Prince Alfred Hospital, New South Wales, Australia. Disease-free survival of patients with a significantly elevated stimulated thyroglobulin level (27.5 µg/l or higher) at the time of ablative radio

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3

Gargya, Ash, and Elizabeth Chua. "Focal Bronchiectasis Causing Abnormal Pulmonary Radioiodine Uptake in a Patient with Well-Differentiated Papillary Thyroid Carcinoma." Case Reports in Endocrinology 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/452758.

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Background. False-positive pulmonary radioactive iodine uptake in the followup of differentiated thyroid carcinoma has been reported in patients with certain respiratory conditions.Patient Findings. We describe a case of well-differentiated papillary thyroid carcinoma treated by total thyroidectomy and radioiodine ablation therapy. Postablation radioiodine whole body scan and subsequent diagnostic radioiodine whole body scans have shown persistent uptake in the left hemithorax despite an undetectable stimulated serum thyroglobulin in the absence of interfering thyroglobulin antibodies. Contras

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4

Jiang, Yuyan, Jiahui Jin, Jingzheng Fan, et al. "Urinary iodine concentration and radioactive iodine therapeutic response in patients with differentiated thyroid cancer." Biomarkers in Medicine 15, no. 11 (2021): 879–90. http://dx.doi.org/10.2217/bmm-2020-0745.

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Aim: Urinary iodine concentration (UIC) may assess radioactive iodine ablation. Materials & methods: According the 2015 American Thyroid Association guidelines, patients were categorized into low- to intermediate-risk or high-risk groups. The iodine concentration in the morning urine specimens was measured by the ceric ion-arsenious acid method. Results: In the low- to intermediate-risk group (113 cases), nonexcellent response (non-ER) was associated with higher UIC, higher UIC subgroups (p < 0.05), higher pre-ablative stimulated thyroglobulin levels (p < 0.01). In the high-risk grou

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5

Wang, Chen, Xin Zhang, Hui Li, Xin Li, and Yansong Lin. "Quantitative thyroglobulin response to radioactive iodine treatment in predicting radioactive iodine-refractory thyroid cancer with pulmonary metastasis." PLOS ONE 12, no. 7 (2017): e0179664. http://dx.doi.org/10.1371/journal.pone.0179664.

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6

SHIBUYA, Koichi, Kiyonori YAMAOKA, Tomohiro NAGAMATSU, Katsumi HANAMOTO, Shoji KAWASAKI, and Yoshio HIRAKI. "Simple and Easy Method for Measurement of Airborne Radioactive Iodine(125I)." RADIOISOTOPES 51, no. 2 (2002): 66–70. http://dx.doi.org/10.3769/radioisotopes.51.66.

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7

Kwong, Norra, Ellen Marqusee, Michael S. Gordon, et al. "Long-term, treatment-free survival in select patients with distant metastatic papillary thyroid cancer." Endocrine Connections 3, no. 4 (2014): 207–14. http://dx.doi.org/10.1530/ec-14-0097.

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Well-differentiated thyroid carcinoma (WDTC) generally has a favorable prognosis. However, patients with distant metastatic disease experience progression of disease with a higher mortality. A subset of patients not previously described may challenge the conventional dogma regarding the progressive nature of all metastatic WDTC. Through analysis of our database, we identified patients with distant metastatic WDTC and persistent, minimally progressive disease. In all patients, persistent metastatic disease was confirmed via tissue biopsy, abnormal PET scan, and/or biochemical elevations in thyr

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8

Carhill, Aubrey A., and Rena Vassilopoulou-Sellin. "Durable Effect of Radioactive Iodine in a Patient with Metastatic Follicular Thyroid Carcinoma." Case Reports in Endocrinology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/231912.

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Objective. Thyroid cancer is the most common endocrine malignancy and fastest increasing of all cancers in both men and women in the United States. Traditionally, differentiated thyroid cancer (DTC) carries a good prognosis when diagnosed early, but increasingly patients are presenting with late-stage disease and bone metastasis which carries a poor prognosis. Treatment of DTC involves surgical resection followed by radioactive iodine (RAI), which conventionally is thought to reach maximal effectiveness between 6 and 12 months following treatment. We report a case and review the literature sur

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9

Slonimsky, Einat, and Mark Tulchinsky. "Radiotheragnostics Paradigm for Radioactive Iodine (Iodide) Management of Differentiated Thyroid Cancer." Current Pharmaceutical Design 26, no. 31 (2020): 3812–27. http://dx.doi.org/10.2174/1381612826666200605121054.

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: This review of radioactive iodide treatment (RAIT) extends from historical origins to its modern utilization in differentiated thyroid cancer (DTC). The principles embedded in the radiotheragnostics (RTGs) paradigm are detailed. : The diverse approaches in current practice are addressed, and this broad variability represents a major weakness that erodes our specialty’s trust-based relationship with patients and referring physicians. The currently developing inter-specialty collaboration should be hailed as a positive change. It promises to clarify the target-based terminology for RAIT. It de

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10

Rothenberg, Stephen M., David G. McFadden, Edwin Palmer, Gilbert H. Daniels, and Lori J. Wirth. "Re-differentiation of radioiodine-refractory BRAF V600E-mutant thyroid carcinoma with dabrafenib: A pilot study." Journal of Clinical Oncology 31, no. 15_suppl (2013): 6025. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.6025.

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6025 Background: Resistance to radioactive iodine is a leading cause of mortality in differentiated thyroid carcinoma. The MAPK pathway is a major determinant of iodine uptake into thyroid carcinoma cells. Mutations in BRAF activate this pathway, resulting in resistance to radioactive iodine. A pilot study using the MEK1/2 inhibitor, selumetinib, (Ho, ASCO 2012) increased radioiodine uptake in a subset of thyroid cancers. Methods: This is a single institution, single arm pilot study investigating the potential for the BRAF inhibitor dabrafenib to induce radioiodine uptake in metastatic, BRAF-m

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11

YASUYO, Iino. "Basic Studies of Radioactive Iodine Waste Concentration Using Paper Membrane Bearing Trimethylhydroxypropylammonium Groups." RADIOISOTOPES 60, no. 3 (2011): 99–107. http://dx.doi.org/10.3769/radioisotopes.60.99.

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12

HANAMOTO, Yukio, Katsuyoshi TATENUMA, Tomoya TAKUWA, Akihiro HIO, Junji KONISHI, and Kanji KASAGI. "Study on an Advanced Treatment System for Medical Waste Drainage. (I). Containing Radioactive Iodine." RADIOISOTOPES 51, no. 7 (2002): 261–65. http://dx.doi.org/10.3769/radioisotopes.51.261.

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13

Vrndic, Olgica B., Svetlana B. Savin, Ljiljana C. Mijatovic, Aleksandar A. Djukic, Ilija D. Jeftic, and Snezana T. Zivancevic Simonovic. "Concentration of Thyroglobulin and Thyroglobulin-Specific Autoantibodies in Patients With Differentiated Thyroid Cancer After Treatment With Radioactive Iodine 131." Laboratory Medicine 42, no. 1 (2011): 27–31. http://dx.doi.org/10.1309/lmnc7i58jnjmcpkw.

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14

Romero, Fabiola, Sandra Galeano, Francisco Cabrera, et al. "Utility of Stimulated Thyroglobulin in the Differentiate Thyroid Cancer." Journal of the Endocrine Society 5, Supplement_1 (2021): A874. http://dx.doi.org/10.1210/jendso/bvab048.1786.

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Abstract Introduction: The treatment of differentiated thyroid cancer has changed considerably, total thyroidectomy and radioactive iodine ablation represented the initial treatment for these patients, currently with a great debate around the choice of which patient should undergo ablation with radioactive iodine in the post-surgical period. Objective: To determine the values of stimulated thyroglobulin (in hypothyroidism) in patients with differentiated thyroid carcinoma who have had surgery and its relationship with the ATA 2015 recurrence risk stratification and the presence of distant or l

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15

Wilson, William A., Joseph Valentino, Thomas Gal, et al. "Excellent long-term control in locoregionally recurrent radioactive iodine-refractory papillary thyroid cancer with the addition of external beam radiation therapy to maximal surgical resection." Journal of Clinical Oncology 30, no. 15_suppl (2012): e16035-e16035. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e16035.

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e16035 Background: Locoregionally recurrent radioactive iodine (RAI) refractory papillary thyroid cancer represents a small percentage of papillary thyroid cancers but is an aggressive disease with significantly lower survival rates. This retrospective review is our experience with these cancers treated with maximal surgical resection followed by external beam radiotherapy. Methods: 26 patients treated from 2001-2011 were eligible for review. After obtaining IRB approval, medical records were reviewed for clinical outcome. All patients had histologically proven recurrences that were negative o

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16

Yéléhé-Okouma, Mélissa, Catherine Malaplate, Nadine Petitpain, et al. "IMMUNOGLOBULIN PREPARATIONS CAN MISLEAD CLINICAL DECISION-MAKING IN FOLLOW-UP OF DIFFERENTIATED THYROID CANCER." Endocrine Practice 26, no. 9 (2020): 1031–38. http://dx.doi.org/10.4158/ep-2020-0053.

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Objective: Intravenous and subcutaneous immunoglobulins are commonly used for immune substitution or as immune modulators in a variety of inflammatory and autoimmune disorders. Exogenous thyroid-specific thyroglobulin (Tg) antibodies present in the donor plasma may interfere with the interpretation of measurements of Tg autoantibodies (Tg-Abs) in the recipient’s plasma and potentially trigger an immune response in the recipient’s immune cells. Levels of antibodies causing bioassay interferences or those leading to clinically relevant changes in patient outcomes are not known. Tg is used as a b

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17

AMANO, Ryohei, Atsushi ANDO, Tatsunosuke HIRAKI, Norihisa TONAMI, and Kinichi HISADA. "Thallium-201 radioactive implant induced X-ray emission scanning of stable iodine distribution in thyroid - Phantom experiment." RADIOISOTOPES 35, no. 5 (1986): 266–69. http://dx.doi.org/10.3769/radioisotopes.35.5_266.

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18

Suksompong, Tanate, Sirikanjana Thongmee, and Wanwisa Sudprasert. "Efficacy of a Graphene Oxide/Chitosan Sponge for Removal of Radioactive Iodine-131 from Aqueous Solutions." Life 11, no. 7 (2021): 721. http://dx.doi.org/10.3390/life11070721.

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Iodine-131 is increasingly used for diagnostic and therapeutic applications. The excretion of radioactive iodine is primarily through the urine. The safe disposal of radioactive waste is an important component of overall hospital waste management. This study investigated the feasibility of using graphene oxide/chitosan (GO/CS) sponges as an adsorbent for the removal of iodine-131 from aqueous solutions. The adsorption efficiency was investigated using iodine-131 radioisotopes to confirm the results in conjunction with stable isotopes. The results revealed that the synthetic structure consists

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19

Wang, Lihua, Canhua Yun, Fengyan Huang, et al. "Preablative Stimulated Thyroglobulin and Thyroglobulin Reduction Index as Decision-Making Markers for Second Radioactive Iodine Therapy in Patients with Structural Incomplete Response." Cancer Management and Research Volume 13 (July 2021): 5351–60. http://dx.doi.org/10.2147/cmar.s314621.

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20

Deng, Yuying, Guoquan Zhu, Wei Ouyang, et al. "SIZE OF THE LARGEST METASTATIC FOCUS TO THE LYMPH NODE IS ASSOCIATED WITH INCOMPLETE RESPONSE OF PN1 PAPILLARY THYROID CARCINOMA." Endocrine Practice 25, no. 9 (2019): 887–98. http://dx.doi.org/10.4158/ep-2018-0583.

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Objective: To evaluate the influence of the size of the metastatic focus in lymph nodes (LNs) on therapeutic response among papillary thyroid cancer (PTC) and cervical pathologically proven LN metastases (pN1). Methods: Patients with pN1 PTC who underwent total or near-total thyroidectomy, LN dissection, and postoperative radioactive iodine therapy in a university hospital between 2014 and 2016 were retrospectively reviewed. Furthermore, 554 patients were assigned to three groups according to the size of the metastatic focus in the LNs (≤0.2 cm, 0.2 to 1.0 cm, ≥1.0 cm). Structural incomplete r

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21

Papaleontiou, Maria. "Early Postoperative Unstimulated Serum Thyroglobulin Predicts Utility of Radioactive Iodine in Patients with Papillary Thyroid Cancer." Clinical Thyroidology 31, no. 11 (2019): 482–85. http://dx.doi.org/10.1089/ct.2019;31.482-485.

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22

Gomez-Hernandez, Karen, and Shereen Ezzat. "Lessons learned from thyroglobulin concentrations after total thyroidectomy and radioactive iodine ablation for differentiated thyroid cancer." Clinical Biochemistry 48, no. 12 (2015): 747–48. http://dx.doi.org/10.1016/j.clinbiochem.2015.07.006.

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23

Fatourechi, Vahab, John C. Morris, and Thomas J. Sebo. "Coexistence of Radioactive Iodine-Resistant Benign Struma Ovarii with Cervical Primary Papillary Cancer of the Thyroid: An Unusual Cause of Thyroglobulin-Positive Radioactive Iodine-Negative Whole-Body Scans." Thyroid 24, no. 9 (2014): 1432–34. http://dx.doi.org/10.1089/thy.2014.0010.

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24

Barres, Bertrand, Antony Kelly, Fabrice Kwiatkowski, et al. "Stimulated Thyroglobulin and Thyroglobulin Reduction Index Predict Excellent Response in Differentiated Thyroid Cancers." Journal of Clinical Endocrinology & Metabolism 104, no. 8 (2019): 3462–72. http://dx.doi.org/10.1210/jc.2018-02680.

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Abstract Context Despite its good prognosis, differentiated thyroid cancer (DTC) is characterized by high rates of disease persistence and recurrence. Estimation of long-term remission (excellent response) thanks to specific parameters could help to individualize the active surveillance schedule. Objective Evaluation of the ability of stimulated thyroglobulin (Tg) and Tg reduction index (TRI) to predict long-term remission in patients with DTC managed by thyroidectomy and radioactive iodine (RAI) remnant ablation. Patients and Interventions Observational retrospective study of 1093 patients tr

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25

Liu, Yan-Qing, Hui Li, Jie-Rui Liu, and Yan-Song Lin. "UNFAVORABLE RESPONSES TO RADIOIODINE THERAPY IN N1B PAPILLARY THYROID CANCER: A PROPENSITY SCORE MATCHING STUDY." Endocrine Practice 25, no. 12 (2019): 1286–94. http://dx.doi.org/10.4158/ep-2019-0155.

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Objective: Regional nodal metastases carry prognostic significance in papillary thyroid cancer (PTC). However, whether different locational nodal metastases correlate with different therapeutic responses remains controversial. We innovatively applied the response to therapy restratification system to evaluate the dynamic disease status after surgery and radioactive iodine (RAI) therapy in PTC patients with different locational nodal metastases. Methods: A total of 585 nondistant-metastatic PTC patients who underwent total thyroidectomy and RAI therapy were retrospectively enrolled. Patients wi

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26

Rosario, P. W. "Anti-thyroglobulin antibodies and risk of finding iodine avid metastases on post-radioactive iodine ablation scan in low-risk thyroid cancer patients." Journal of Endocrinological Investigation 40, no. 9 (2017): 1023. http://dx.doi.org/10.1007/s40618-017-0704-0.

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27

Shin, Dong Hun, Yoon Jung Kang, Joo Seung Park, et al. "Serum Thyroglobulin Varies according to Thyrotropin Levels during Preparation for Treatment by Radioactive Iodine Ablation and Scan." Korean Journal of Endocrine Surgery 12, no. 1 (2012): 21. http://dx.doi.org/10.16956/kjes.2012.12.1.21.

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28

Rosario, Pedro Weslley, Gabriela Franco Mourão, Juan Bernard Nascimento dos Santos, and Maria Regina Calsolari. "Is Empirical Radioactive Iodine Therapy Still a Valid Approach to Patients with Thyroid Cancer and Elevated Thyroglobulin?" Thyroid 24, no. 3 (2014): 533–36. http://dx.doi.org/10.1089/thy.2013.0427.

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29

Sawka, Anna M., Steven Orlov, Jacob Gelberg, et al. "Prognostic value of postsurgical stimulated thyroglobulin levels after initial radioactive iodine therapy in well-differentiated thyroid carcinoma." Head & Neck 30, no. 6 (2008): 693–700. http://dx.doi.org/10.1002/hed.20755.

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30

Choi, Joon Ho, Ilhan Lim, Inki Lee, et al. "An enhanced treatment effect can be expected from a higher serum thyroglobulin level after radioactive iodine therapy." Annals of Nuclear Medicine 33, no. 2 (2018): 128–34. http://dx.doi.org/10.1007/s12149-018-1313-5.

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31

Park, Sohyun, Ji-In Bang, Ho-Young Lee, and Sang-Eun Kim. "Does 131I Radioactivity Interfere with Thyroglobulin Measurement in Patients Undergoing Radioactive Iodine Therapy with Recombinant Human TSH?" Nuclear Medicine and Molecular Imaging 49, no. 2 (2015): 122–26. http://dx.doi.org/10.1007/s13139-014-0317-x.

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32

Manevska, Nevena, Sinisa Stojanoski, Tanja Makazlieva, and Anamarija Jovanovska. "FALSE POSITIVE RADIOIODINE POST-ABLATION SCAN IN SCALP REGION IN A WOMAN WHO USED HAIR COLORING REVEALED BY SPECT/CT." AACE Clinical Case Reports 5, no. 5 (2019): e311-e315. http://dx.doi.org/10.4158/accr-2018-0593.

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Objective: Radioiodine ablation with iodine-131 is a standard therapeutic procedure for patients diagnosed with differentiated thyroid carcinoma (DTC). We present a contamination artifact on whole-body scan (WBS), after radioiodine ablation due to papillary thyroid carcinoma. The hybrid imaging resolved the question of metastasis versus contamination. Methods: In the case of 35-year-old female patient we used a General Electric hybrid gamma camera with a high-energy-general-purpose collimator for performing WBS, and single photon emission computed tomography combined with low dose computed tom

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33

Zayouna, Christine, Hajerah Sonnabend, and Ambika Amblee. "Radioactive Iodine Resistant Papillary Thyroid Cancer “Redifferentiated” With Dabrafenib." Journal of the Endocrine Society 5, Supplement_1 (2021): A898. http://dx.doi.org/10.1210/jendso/bvab048.1833.

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Abstract Background: Differentiated thyroid cancers (DTC) make up 95% of all thyroid cancers. Radioactive iodine therapy (RAI Rx) is an integral part of DTC management. However, 5-15% of DTC and 50% of metastatic DTC become resistant to RAI Rx and carries a 10-year survival of only 10%. One of the newer therapeutic options target “redifferentiation” of the tumor using RAI sensitizers, notably with short-term use of tyrosine kinase inhibitors (TKI). Clinical Case: A 62-year-old women with a 3-year history of Papillary TC s/p surgery (Sx) and 175 mCi RAI presented to establish care and was found

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34

Alvear Rodriguez, Carlos A., and José Rafael Tovar Cuevas. "Regression models with asymmetric data for estimating thyroglobulin levels one year after the ablation of thyroid cancer." Statistical Methods in Medical Research 28, no. 8 (2018): 2258–75. http://dx.doi.org/10.1177/0962280218764006.

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A key biomarker in the study of differentiated thyroid cancer is thyroglobulin. Measurements of the levels of this protein in the blood are determined using laboratory instruments that cannot detect very small concentrations below a threshold, generating left-censored measurements. In the presence of censoring, ordinary least-squares regression models generate biased parameter estimates; therefore, it is necessary to resort to more complex models that consider the censored observations and the behavior of the distribution of the response variable, such as censored and mixed regression models.

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35

Vorasart, Pakaworn, and Chutintorn Sriphrapradang. "Factitious thyrotoxicosis: how to find it." Diagnosis 7, no. 2 (2020): 141–45. http://dx.doi.org/10.1515/dx-2019-0015.

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AbstractBackgroundAlthough the most common cause of thyrotoxicosis is Graves’ disease, the determination of the cause of thyrotoxicosis is important for establishing appropriate management. Diagnosis of surreptitious ingestion of thyroid hormones or factitious thyrotoxicosis often presents a difficult challenge especially in a patient with previously diagnosed Graves’ disease. The objective of this report was to demonstrate various approaches to support the diagnosis of factitious thyrotoxicosis.Case presentationWe describe a patient with underlying Graves’ disease who underwent definitive the

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36

Anderson, Peter D., and Gyula Bokor. "Nuclear and Radiological Terrorism." Journal of Pharmacy Practice 26, no. 3 (2013): 171–82. http://dx.doi.org/10.1177/0897190012474238.

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Terrorism involving radioactive materials includes improvised nuclear devices, radiation exposure devices, contamination of food sources, radiation dispersal devices, or an attack on a nuclear power plant or a facility/vehicle that houses radioactive materials. Ionizing radiation removes electrons from atoms and changes the valence of the electrons enabling chemical reactions with elements that normally do not occur. Ionizing radiation includes alpha rays, beta rays, gamma rays, and neutron radiation. The effects of radiation consist of stochastic and deterministic effects. Cancer is the typic

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37

TAKUWA, Tomoya, Akihiro HIO, Katsuyoshi TATENUMA, Yukio HANAMOTO, Junji KONISHI, and Kanji KASAGI. "Study on an Advanced Treatment System for Medical Waste Drainage Containing Radioactive Iodine. II. In-place Test Using Drainage in a Medical Facility." RADIOISOTOPES 51, no. 8 (2002): 296–300. http://dx.doi.org/10.3769/radioisotopes.51.296.

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38

Zhang, Xieyi, Tetsuya Higuchi, Hiroyasu Tomonaga, et al. "Early detection of progressive disease using thyroglobulin doubling-time in metastatic differentiated thyroid carcinoma treated with radioactive iodine." Nuclear Medicine Communications 41, no. 4 (2020): 350–55. http://dx.doi.org/10.1097/mnm.0000000000001154.

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39

Shinohara, S., M. Kikuchi, A. Suehiro, et al. "Characteristics and prognosis of patients with thyroglobulin-positive and radioactive iodine whole-body scan-negative differentiated thyroid carcinoma." Japanese Journal of Clinical Oncology 45, no. 5 (2015): 427–32. http://dx.doi.org/10.1093/jjco/hyv021.

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40

Usenko, V. S., E. A. Lepekhin, I. N. Kornilovska, et al. "Immunohistochemical study of fibronectin and thyroglobulin in the thyroid gland of female rats after exposure to radioactive iodine." Anatomical Record 252, no. 4 (1998): 600–607. http://dx.doi.org/10.1002/(sici)1097-0185(199812)252:4<600::aid-ar10>3.0.co;2-e.

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41

Stati, V., A. Di Paolo, G. Campagna, A. Tofani, and A. Signore. "1748P Predictive role of serum thyroglobulin after surgery and radioactive iodine therapy in patients with differentiated thyroid carcinoma." Annals of Oncology 32 (September 2021): S1206. http://dx.doi.org/10.1016/j.annonc.2021.08.894.

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42

Malik, Nilma, Alyaksandr V. Nikitski, Elie Klam, et al. "MOLECULAR PROFILE AND CLINICAL OUTCOMES IN DIFFERENTIATED THYROID CANCER PATIENTS PRESENTING WITH BONE METASTASIS." Endocrine Practice 25, no. 12 (2019): 1255–62. http://dx.doi.org/10.4158/ep-2019-0265.

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Objective: Differentiated thyroid cancer patients uncommonly present with bone metastasis as the initial manifestation. Their molecular profile is largely unknown. The aim of this study was to evaluate the histopathology, molecular profiles, and response to radioactive iodine therapy in these patients. Methods: Eight patients presented with symptomatic bone metastasis from an unknown primary tumor. We identified these patients by performing a retrospective chart review. Pathology slides were reviewed and the molecular analysis of 112 thyroid cancer-related genes was performed on bone metastasi

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43

Al-Alawy, Iman Tarik, and Raghad Saadoon Mohammed. "Nuclear Data Relevant to the Production of Radioiodine I-123, I-125 by Indirect Route and Medical Applications." International Letters of Chemistry, Physics and Astronomy 63 (January 2016): 90–97. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.63.90.

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The use of radioactive Iodine plays an important role in the treatment of some diseases and diagnosis of others, since they have suitable half-life. The radioactivity emitted from the dissolution of radioactive I-123 and I-125, such as the emission of Auger electrons, positrons and gamma rays reduce the spread of these diseases. Therefore, in this work we discuss the Iodine production via indirect reactions. In order to calculate the cross sections of these reactions for the mentioned target elements, we recommended the cross sections for EXFOR library using the recom.m program, which is writt

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44

Bandeira, Leonardo, Rosália do Prado Padovani, Ana Luiza Ticly, et al. "Thyroglobulin levels before radioactive iodine therapy and dynamic risk stratification after 1 year in patients with differentiated thyroid cancer." Archives of Endocrinology and Metabolism 61, no. 6 (2017): 590–99. http://dx.doi.org/10.1590/2359-3997000000308.

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45

Wise-Oringer, Brittany K., Marina Goldis, Molly O. Regelmann, et al. "Thyroid Ultrasound: More Sensitive than Radioactive Iodine Imaging in Detecting Recurrence of Papillary Thyroid Cancer in Two Pediatric Patients." Hormone Research in Paediatrics 90, no. 1 (2018): 66–72. http://dx.doi.org/10.1159/000487436.

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Background: Papillary thyroid cancer (PTC) is an uncommon pediatric disease with an excellent prognosis. In follow-up surveillance, neck ultrasound (US), basal and thyroid-stimulating hormone-stimulated serum thyroglobulin (Tg) levels, and diagnostic whole-body radioactive iodine scans (DxWBS) have been traditionally used in both adults and children for the detection of recurrence or metastases of PTC. Methods: Two pediatric patients with metastatic PTC were followed after standard ablative treatment with routine neck US and serum Tg levels, as well as periodic DxWBS. Results: Neck US identifi

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46

Bates, Maria F., Kristin L. Long, and Rebecca S. Sippel. "Ensuring Quality in Thyroid Cancer Surgery." US Endocrinology 13, no. 01 (2017): 22. http://dx.doi.org/10.17925/use.2017.13.01.22.

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Thyroid cancer incidence is increasing worldwide. Though long-term survival rates are excellent, recurrence remains a significant problem, which highlights potential areas of needed improvement, including the surgical care of these patients. This review paper identifies tools and markers that can be used to improve surgical quality in thyroid cancer. Preoperative surgical planning starts with an adequate ultrasound evaluation of the cervical lymph node basins. Postoperatively, thyroglobulin and radioactive iodine uptake scans can track adequacy of resection. In addition, lymph node yield and l

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Momesso, Denise P., Fernanda Vaisman, Samantha P. Yang, et al. "Dynamic Risk Stratification in Patients with Differentiated Thyroid Cancer Treated Without Radioactive Iodine." Journal of Clinical Endocrinology & Metabolism 101, no. 7 (2016): 2692–700. http://dx.doi.org/10.1210/jc.2015-4290.

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Context: Although response to therapy assessment is a validated tool for dynamic risk stratification in patients with differentiated thyroid cancer (DTC) treated with total thyroidectomy (TT) and radioactive iodine therapy (RAI), it has not been well studied in patients treated with lobectomy or TT without RAI. Because these responses to therapy definitions are heavily dependent on serum thyroglobulin (Tg) levels, modifications of the original definitions were needed to appropriately classify patients treated without RAI. Objective: This study aimed to validate the response to therapy assessme

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Kim, Eun Young, Kee Hoon Hyun, Yong Lai Park, Chan Heun Park, and Ji-Sup Yun. "Risk factors associated with high thyroglobulin level following radioactive iodine ablation, measured 12 months after treatment for papillary thyroid carcinoma." Annals of Surgical Treatment and Research 92, no. 1 (2017): 1. http://dx.doi.org/10.4174/astr.2017.92.1.1.

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Angell, Trevor E., Carole A. Spencer, Barbara D. Rubino, John T. Nicoloff, and Jonathan S. LoPresti. "In Search of an Unstimulated Thyroglobulin Baseline Value in Low-Risk Papillary Thyroid Carcinoma Patients Not Receiving Radioactive Iodine Ablation." Thyroid 24, no. 7 (2014): 1127–33. http://dx.doi.org/10.1089/thy.2013.0691.

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Rosario, Pedro Weslley. "Postoperative Unstimulated Thyroglobulin for the Decision to Use Radioactive Iodine in Patients with Low- or Intermediate-Risk Papillary Thyroid Carcinoma." Annals of Surgical Oncology 26, S3 (2019): 867–68. http://dx.doi.org/10.1245/s10434-019-07722-z.

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