Academic literature on the topic 'Ion channels and transporters for potassium'

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Journal articles on the topic "Ion channels and transporters for potassium"

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Demirbilek, Huseyin, Sonya Galcheva, Dogus Vuralli, Sara Al-Khawaga, and Khalid Hussain. "Ion Transporters, Channelopathies, and Glucose Disorders." International Journal of Molecular Sciences 20, no. 10 (2019): 2590. http://dx.doi.org/10.3390/ijms20102590.

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Ion channels and transporters play essential roles in excitable cells including cardiac, skeletal and smooth muscle cells, neurons, and endocrine cells. In pancreatic beta-cells, for example, potassium KATP channels link the metabolic signals generated inside the cell to changes in the beta-cell membrane potential, and ultimately regulate insulin secretion. Mutations in the genes encoding some ion transporter and channel proteins lead to disorders of glucose homeostasis (hyperinsulinaemic hypoglycaemia and different forms of diabetes mellitus). Pancreatic KATP, Non-KATP, and some calcium chann
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Yuan, Dumin, Zhiyuan Ma, Biguang Tuo, Taolang Li, and Xuemei Liu. "Physiological Significance of Ion Transporters and Channels in the Stomach and Pathophysiological Relevance in Gastric Cancer." Evidence-Based Complementary and Alternative Medicine 2020 (February 13, 2020): 1–10. http://dx.doi.org/10.1155/2020/2869138.

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Gastric cancer (GC) is a highly invasive and fatal malignant disease that accounts for 5.7% of new global cancer cases and is the third leading cause of cancer-related death. Acid/base homeostasis is critical for organisms because protein and enzyme function, cellular structure, and plasma membrane permeability change with pH. Various ion transporters are expressed in normal gastric mucosal epithelial cells and regulate gastric acid secretion, ion transport, and fluid absorption, thereby stabilizing the differentiation and homeostasis of gastric mucosal epithelial cells. Ion transporter dysfun
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Nakamura, Kazuyoshi, Hikaru Hayashi, and Manabu Kubokawa. "Proinflammatory Cytokines and Potassium Channels in the Kidney." Mediators of Inflammation 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/362768.

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Proinflammatory cytokines affect several cell functions via receptor-mediated processes. In the kidney, functions of transporters and ion channels along the nephron are also affected by some cytokines. Among these, alteration of activity of potassium ion (K+) channels induces changes in transepithelial transport of solutes and water in the kidney, since K+channels in tubule cells are indispensable for formation of membrane potential which serves as a driving force for the transepithelial transport. Altered K+channel activity may be involved in renal cell dysfunction during inflammation. Althou
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Akyuz, Enes, Zuleyha Doganyigit, Yam Nath Paudel, et al. "Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy." Life 11, no. 4 (2021): 276. http://dx.doi.org/10.3390/life11040276.

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Epilepsy is characterized by an imbalance in neurotransmitter activity; an increased excitatory to an inhibitory activity. Acetylcholine (ACh), serotonin, and norepinephrine (NE) may modulate neural activity via several mechanisms, mainly through its receptors/transporter activity and alterations in the extracellular potassium (K+) concentration via K+ ion channels. Seizures may disrupt the regulation of inwardly rectifying K+ (Kir) channels and alter the receptor/transporter activity. However, there are limited data present on the immunoreactivity pattern of these neurotransmitter receptors/t
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Sopjani, Mentor, Lulzim Millaku, Dashnor Nebija, Merita Emini, Arleta Rifati-Nixha, and Miribane Dërmaku-Sopjani. "The Glycogen Synthase Kinase-3 in the Regulation of Ion Channels and Cellular Carriers." Current Medicinal Chemistry 26, no. 37 (2019): 6817–29. http://dx.doi.org/10.2174/0929867325666181009122452.

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Glycogen synthase kinase-3 (GSK-3) is a highly evolutionarily conserved and ubiquitously expressed serine/threonine kinase, an enzyme protein profoundly specific for glycogen synthase (GS). GSK-3 is involved in various cellular functions and physiological processes, including cell proliferation, differentiation, motility, and survival as well as glycogen metabolism, protein synthesis, and apoptosis. There are two isoforms of human GSK-3 (named GSK-3α and GSK-3β) encoded by two distinct genes. Recently, GSK-3β has been reported to function as a powerful regulator of various transport processes
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Feng, Xinghua, Zhuangzhuang Zhao, Qian Li, and Zhiyong Tan. "Lysosomal Potassium Channels: Potential Roles in Lysosomal Function and Neurodegenerative Diseases." CNS & Neurological Disorders - Drug Targets 17, no. 4 (2018): 261–66. http://dx.doi.org/10.2174/1871527317666180202110717.

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Background & Objective: The lysosome is a membrane-enclosed organelle widely found in every eukaryotic cell. It has been deemed as the stomach of the cells. Recent studies revealed that it also functions as an intracellular calcium store and is a platform for nutrient-dependent signal transduction. Similar with the plasma membrane, the lysosome membrane is furnished with various proteins, including pumps, ion channels and transporters. So far, two types of lysosomal potassium channels have been identified: large-conductance and Ca2+-activated potassium channel (BK) and TMEM175. TMEM175 has
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Quraishi, Imran H., and Robert M. Raphael. "Computational model of vectorial potassium transport by cochlear marginal cells and vestibular dark cells." American Journal of Physiology-Cell Physiology 292, no. 1 (2007): C591—C602. http://dx.doi.org/10.1152/ajpcell.00560.2005.

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Cochlear marginal cells and vestibular dark cells transport potassium into the inner ear endolymph, a potassium-rich fluid, the homeostasis of which is essential for hearing and balance. We have formulated an integrated mathematical model of ion transport across these epithelia that incorporates the biophysical properties of the major ion transporters and channels located in the apical and basolateral membranes of the constituent cells. The model is constructed for both open- and short-circuit situations to test the extremes of functional capacity of the epithelium and predicts the steady-stat
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Kolb, Alexander R., Teresa M. Buck, and Jeffrey L. Brodsky. "Saccharomyces cerivisiae as a model system for kidney disease: what can yeast tell us about renal function?" American Journal of Physiology-Renal Physiology 301, no. 1 (2011): F1—F11. http://dx.doi.org/10.1152/ajprenal.00141.2011.

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Ion channels, solute transporters, aquaporins, and factors required for signal transduction are vital for kidney function. Because mutations in these proteins or in associated regulatory factors can lead to disease, an investigation into their biogenesis, activities, and interplay with other proteins is essential. To this end, the yeast, Saccharomyces cerevisiae , represents a powerful experimental system. Proteins expressed in yeast include the following: 1) ion channels, including the epithelial sodium channel, members of the inward rectifying potassium channel family, and cystic fibrosis tr
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Kang, Tong Mook, Vladislav S. Markin, and Donald W. Hilgemann. "Ion Fluxes in Giant Excised Cardiac Membrane Patches Detected and Quantified with Ion-selective Microelectrodes." Journal of General Physiology 121, no. 4 (2003): 325–48. http://dx.doi.org/10.1085/jgp.200208777.

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We have used ion-selective electrodes (ISEs) to quantify ion fluxes across giant membrane patches by measuring and simulating ion gradients on both membrane sides. Experimental conditions are selected with low concentrations of the ions detected on the membrane side being monitored. For detection from the cytoplasmic (bath) side, the patch pipette is oscillated laterally in front of an ISE. For detection on the extracellular (pipette) side, ISEs are fabricated from flexible quartz capillary tubing (tip diameters, 2–3 microns), and an ISE is positioned carefully within the patch pipette with th
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Agarkova, Irina, David Dunigan, James Gurnon, et al. "Chlorovirus-Mediated Membrane Depolarization of Chlorella Alters Secondary Active Transport of Solutes." Journal of Virology 82, no. 24 (2008): 12181–90. http://dx.doi.org/10.1128/jvi.01687-08.

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ABSTRACT Paramecium bursaria chlorella virus 1 (PBCV-1) is the prototype of a family of large, double-stranded DNA, plaque-forming viruses that infect certain eukaryotic chlorella-like green algae from the genus Chlorovirus. PBCV-1 infection results in rapid host membrane depolarization and potassium ion release. One interesting feature of certain chloroviruses is that they code for functional potassium ion-selective channel proteins (Kcv) that are considered responsible for the host membrane depolarization and, as a consequence, the efflux of potassium ions. This report examines the relations
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Dissertations / Theses on the topic "Ion channels and transporters for potassium"

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Houdinet, Gabriella. "Impact de la symbiose racinaire dans l’adaptation des plantes à la carence potassique : caractérisation et rôle de systèmes de transport membranaires chez le champignon ectomycorhizien Hebeloma cylindrosporum." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTG067.

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L’un des rôles majeurs concernant les interactions bénéfiques entre les plantes et les champignons est l’amélioration de la nutrition des plantes en échangeant des nutriments, grâce à une meilleure exploration du sol et une meilleure absorption de l’eau et des ions. Par conséquent, la symbiose ectomycorhizienne, établie entre des espèces de plantes ligneuses et des champignons du sol, est cruciale pour que la plante puisse absorber efficacement les minéraux peu disponibles dans les écosystèmes forestiers. Des études physiologiques, des projets de séquençage de génomes récents et des analyses t
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Guerrero, Galan Maria del Carmen. "Impact of the ectomycorrhizal symbiosis for plant adaptation to nutritional and salt stress : characterization and role of potassium channels in the model fungus Hebeloma cylindrosporum." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT142.

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La symbiose ectomycorhizienne, répandue dans les forêts tempérées et boréales, se base sur des échanges nutritionnels entre la plante hôte et des champignons du sol. Ce mutualisme améliore la nutrition minérale et en eau de plantes ligneuses à travers des mécanismes encore méconnus. Ce manuscrit de thèse présente l’ensemble des systèmes de transport membranaire du champignon ectomycorhizien Hebeloma cylindrosporum identifié à partir du génome séquencé, avec un accent sur les gènes dont l’expression est induite en symbiose avec son hôte naturel, le pin maritime (Pinus pinaster). Ces données aid
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Zha, Huiyan, and 查慧艳. "Design, synthesis and characterization of synthetic ion transporters." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/206532.

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In recent decades, small molecules have been widely applied to the generation of functional ion transporters. Major discoveries disclosed in this thesis include a self-assembled chloride-dependent potassium channel candidate, a physiological chloride and bicarbonate dual-transporter, and a series of efficient synthetic ion transporters. In nature, K+ channels play an important role in Ca2+ signaling, volume regulation, secretion, proliferation, and migration. The extracellular K+ concentration (4 mM) is about 40 times lower than the intracellular K+ concentration (160 mM). The opening of K+ c
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Liu, Pengyun, and 劉鵬云. "Design, synthesis, characterization and biological study of ion transporters." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206419.

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Su, Hua. "Cloning and characterization of potassium channels and transporters in Mesembryanthemum crystallinum." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/279912.

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K⁺ contributes most to the osmotic pressure in plant cells. Under saline conditions, accumulation of Na⁺ disturbs the ion homeostasis and causes toxicity to the cell. Potassium channels and transporters may mediate Na⁺ entry, yet K⁺ contents must be maintained at a certain level. Regulation of potassium transport under salt stress is important for ion homeostasis and stress tolerance in plants. This dissertation presents analyses of the potassium channels and transporters in the halophyte Mesembryanthemum crystallinum (common ice plant) emphasizing their regulation in the context of ion homeos
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Chapman, Joanna Claire. "Potassium ion channels and disorders of glucose regulation." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322879.

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Robertson, Janice L. "Modeling of ion behavior in inward rectifier potassium channels /." Access full-text from WCMC, 2009. http://proquest.umi.com/pqdweb?did=1692359571&sid=2&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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McNiven, Alistair Iain. "Electrophysiology of potassium channels in the hamster egg." Thesis, University of Edinburgh, 1989. http://hdl.handle.net/1842/29885.

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FERREIRA, ANDREA DE LIMA. "STUDY OF SODIUM AND POTASSIUM ION CHANNELS VIA STOCHASTIC DYNAMIC." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2011. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=18111@1.

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COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO<br>O presente trabalho apresenta uma revisão sobre os Canais Iônicos de Sódio e de Potássio fazendo uma relacão com os aspectos biofísicos, computacionais e matemáticos. Estudamos os canais iônicos, sob o ponto de vista da Mecânica Estatìstica, mais precisamente, considerando os canais iônicos como um processo markoviano. O objetivo principal deste trabalho é representar a dinâmica dos canais iônicos utilizando a caminhada aleatória e elaborar programas computacionais que sim
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Garg, Vivek. "Regulation of ATP-Sensitive Potassium Channels in the Heart." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1238179085.

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Books on the topic "Ion channels and transporters for potassium"

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E, Clapham David, and Ehrlich Barbara E, eds. Organellar ion channels and transporters. Rockefeller University Press, 1996.

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Sepúlveda, Francisco V., and Francisco Bezanilla, eds. Pumps, Transporters, and Ion Channels. Kluwer Academic Publishers-Plenum Publishers, 2005. http://dx.doi.org/10.1007/b139057.

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Hamilton, Kirk L., and Daniel C. Devor, eds. Studies of Epithelial Transporters and Ion Channels. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55454-5.

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Pumps, channels, and transporters: Methods of functional analysis. John Wiley & Sons, Inc., 2015.

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Hamilton, Kirk L., and Daniel C. Devor, eds. Ion Channels and Transporters of Epithelia in Health and Disease. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3366-2.

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Morad, Martin, Setsuro Ebashi, Wolfgang Trautwein, and Yoshihisa Kurachi, eds. Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-011-3990-8.

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Yuan, Jason X.-J., 1963- and Ward Jeremy P. T, eds. Membrane receptors, channels, and transporters in pulmonary circulation. Springer, 2010.

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Epithelial anion transport in health and disease: The role of the SLC26 transporters family. John Wiley & Sons, 2006.

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Yasunobu, Suketa, and Excerpta Medica (Firm), eds. Control and diseases of sodium dependent transport proteins and ion channels: Proceedings of the First International Conference held in Shizuoka, Japan, 24-28th August 1999. Elsevier, 2000.

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Steinhäuser, Christian, Gerald Seifert, and Joachim W. Deitmer. Physiology of Astrocytes: Ion Channels and Ion Transporters. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199794591.003.0016.

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This is a digitally enhanced text. Readers can also see the coverage of this topic area in the second edition of Neuroglia. The second edition of Neuroglia was first published digitally in Oxford Scholarship Online and the bibliographic details provided, if cited, will direct people to that version of the text. Readers can also see the coverage of this topic area in the ...
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Book chapters on the topic "Ion channels and transporters for potassium"

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Kharade, Sujay V., and Jerod S. Denton. "Small-Molecule Pharmacology of Epithelial Inward Rectifier Potassium Channels." In Studies of Epithelial Transporters and Ion Channels. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-55454-5_21.

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Kharade, Sujay V., and Jerod S. Denton. "Small-Molecule Pharmacology of Epithelial Inward Rectifier Potassium Channels." In Ion Channels and Transporters of Epithelia in Health and Disease. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-3366-2_27.

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Pandey, Girdhar K., and Swati Mahiwal. "Sequence, Structure and Domain Analysis of Potassium Channels and Transporters." In Role of Potassium in Plants. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45953-6_4.

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Becchetti, Andrea, and Patrizia Aracri. "Ion Channels and Transporters." In Molecular Life Sciences. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_190.

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Becchetti, Andrea, and Patrizia Aracri. "Ion Channels and Transporters." In Molecular Life Sciences. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_190-2.

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De Weille, Jan R., and Michel Lazdunski. "Regulation of the ATP-Sensitive Potassium Channel." In Ion Channels. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4615-7305-0_6.

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Kjeldsen, Keld. "Nonrenal Potassium Homeostasis: Hypokalemia and Potassium Depletion—Role of Skeletal Muscle Potassium-Pump (Na+,K+- ATPase)." In Ion Channels and Ion Pumps. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2596-6_16.

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Weik, Ralf. "Potassium Channels in Skeletal Muscle." In Ion Channels and Ion Pumps. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2596-6_14.

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Lingle, Christopher J., Christopher R. Solaro, Murali Prakriya, and Jiu Ping Ding. "Calcium-Activated Potassium Channels in Adrenal Chromaffin Cells." In Ion Channels. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-1775-1_7.

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Robinson, John M., Andrey Kosolapov, and Carol Deutsch. "Tertiary and Quaternary Structure Formation of Voltage-Gated Potassium Channels." In Ion Channels. Humana Press, 2006. http://dx.doi.org/10.1385/1-59745-095-2:41.

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Conference papers on the topic "Ion channels and transporters for potassium"

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Fedorova, E. E., and N. A. Trifonova. "Ion transporters in the root nodule of Medicago truncatula: potassium transporters." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.071.

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The transporter proteins were mistargeted and partly depleted from plasma membrane of mature infected cells, this phenomenon may contribute to the potassium loss by symbiosomes during their development and senescence.
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Stafford, Lewis J., Ross Chambers, Sharon H. Willis, et al. "Abstract 74: Discovery of new therapeutic monoclonal antibodies to challenging GPCRs, ion channels and transporters." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-74.

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Kim, Dong-Kwon, Chuanhua Duan, Yu-Feng Chen, and Arun Majumdar. "Power Generation From Concentration Gradient by Reverse Electrodialysis in Ion Selective Nanochannel." In ASME 2009 7th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2009. http://dx.doi.org/10.1115/icnmm2009-82208.

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In this article, ion selective nanochannels are studied to generate electric power from concentration gradient by reverse electrodialysis. When nanochannels bring into contact with aqueous solution, the surface of nanochannels acquires charges from ionization, ion adsorption, and ion dissolution. These surface charges draw counter-ions toward the surface and repel co-ions away. Therefore, when an electrolyte concentration gradient is applied to nanochannels, counter-ions are transported through nanochannels much more easily than co-ions, which results in a net charge migration of ions. Gibbs f
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Chang, Chen-Ling, John Guofeng Bai, Kyong-Hoon Lee, Jae-Hyun Chung, Yaling Liu, and Wing Kam Liu. "Ion Diffusion Upon Concentrations in Open Nanofluidic Channels." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-42362.

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The ion flow in nanochannels is investigated by using nanochannels in an open configuration that allows the direct observation of fluid diffusion through an optical microscope. An “open nanochannel” is a channel with the top open to air such that fluidics can be introduced from both the entrance and the top of the channels. The experimental results showed that the diffusion length of the potassium chloride and phosphate buffer decreased with their concentration. The observed behaviors were analyzed by the contact angle variation due to the electrowetting phenomena involving the interaction bet
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Li, Zhilin. "Characterization of physiological role of potassium ion channels in the arthropod salivary gland." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.112983.

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Willis, Sharon H., Kimberly Mattia, Riley Payne, et al. "Abstract 656: Discovery of MAbs against difficult GPCRs, ion channels, and transporters using the MPS Discovery Engine®." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-656.

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Cuppoletti, John. "Composite Synthetic Membranes Containing Native and Engineered Transport Proteins." In ASME 2008 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2008. http://dx.doi.org/10.1115/smasis2008-449.

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Our membrane transport protein laboratory has worked with material scientists, computational chemists and electrical and mechanical engineers to design bioactuators and sensing devices. The group has demonstrated that it is possible to produce materials composed native and engineered biological transport proteins in a variety of synthetic porous and solid materials. Biological transport proteins found in nature include pumps, which use energy to produce gradients of solutes, ion channels, which dissipate ion gradients, and a variety of carriers which can either transport substances down gradie
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