Academic literature on the topic 'Ion-RNA Interactions'

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Journal articles on the topic "Ion-RNA Interactions"

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Yu, Tao, Yuhong Zhu, Zhaojian He, and Shi-Jie Chen. "Predicting Molecular Crowding Effects in Ion–RNA Interactions." Journal of Physical Chemistry B 120, no. 34 (2016): 8837–44. http://dx.doi.org/10.1021/acs.jpcb.6b05625.

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Edwards, Thomas E., and Snorri Th Sigurdsson. "EPR spectroscopic analysis of TAR RNA–metal ion interactions." Biochemical and Biophysical Research Communications 303, no. 2 (2003): 721–25. http://dx.doi.org/10.1016/s0006-291x(03)00411-x.

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Fingerhut, Benjamin P., Eva M. Bruening, Jakob Schauss, Torsten Siebert, and Thomas Elsaesser. "Interactions of RNA and Water probed by 2D-IR Spectroscopy." EPJ Web of Conferences 205 (2019): 10003. http://dx.doi.org/10.1051/epjconf/201920510003.

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Combined experimental-theoretical investigation of ultrafast hydration dynamics of an A-form RNA double helix in water reveals an ordered arrangement of water molecules and provides boundary conditions for the ion atmosphere around the polyanionic RNA.
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Edwards, Thomas E., Tamara M. Okonogi, and Snorri Th Sigurdsson. "Investigation of RNA-Protein and RNA-Metal Ion Interactions by Electron Paramagnetic Resonance Spectroscopy." Chemistry & Biology 9, no. 6 (2002): 699–706. http://dx.doi.org/10.1016/s1074-5521(02)00150-3.

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Nguyen, Hung T., Naoto Hori, and D. Thirumalai. "Theory and simulations for RNA folding in mixtures of monovalent and divalent cations." Proceedings of the National Academy of Sciences 116, no. 42 (2019): 21022–30. http://dx.doi.org/10.1073/pnas.1911632116.

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RNA molecules cannot fold in the absence of counterions. Experiments are typically performed in the presence of monovalent and divalent cations. How to treat the impact of a solution containing a mixture of both ion types on RNA folding has remained a challenging problem for decades. By exploiting the large concentration difference between divalent and monovalent ions used in experiments, we develop a theory based on the reference interaction site model (RISM), which allows us to treat divalent cations explicitly while keeping the implicit screening effect due to monovalent ions. Our theory ca
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Le, Shu-Yun, Jih-H. Chen, N. Pattabiraman, and Jacob V. Maizel. "Ion-RNA Interactions in the RNA Pseudoknot of a Ribosomal Frameshifting Site: Molecular Modeling Studies." Journal of Biomolecular Structure and Dynamics 16, no. 1 (1998): 1–11. http://dx.doi.org/10.1080/07391102.1998.10508221.

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Wu, Yuan-Yan, Zhong-Liang Zhang, Jin-Si Zhang, Xiao-Long Zhu, and Zhi-Jie Tan. "Multivalent ion-mediated nucleic acid helix-helix interactions: RNA versus DNA." Nucleic Acids Research 43, no. 12 (2015): 6156–65. http://dx.doi.org/10.1093/nar/gkv570.

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Khan, Mateen A. "Analysis of Ion and pH Effects on Iron Response Element (IRE) and mRNA-Iron Regulatory Protein (IRP1) Interactions." Current Chemical Biology 14, no. 2 (2020): 88–99. http://dx.doi.org/10.2174/2212796814999200604121937.

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Background: Cellular iron uptake, utilization, and storage are tightly controlled through the action of iron regulatory proteins (IRPs). IRPs achieve this control by binding to IREs-mRNA in the 5'- or 3'-end of mRNAs that encode proteins involved in iron metabolism. The interaction of iron regulatory proteins with mRNAs containing an iron responsive element plays a central role in this regulation. The IRE RNA family of mRNA regulatory structures combines absolutely conserved protein binding sites with phylogenetically conserved base pairs that are specific to each IREs and influence RNA/protei
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Lemkul, Justin A. "Same fold, different properties: polarizable molecular dynamics simulations of telomeric and TERRA G-quadruplexes." Nucleic Acids Research 48, no. 2 (2019): 561–75. http://dx.doi.org/10.1093/nar/gkz1154.

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Abstract DNA and RNA sequences rich in guanine can fold into noncanonical structures called G-quadruplexes (GQs), which exhibit a common stem structure of Hoogsteen hydrogen-bonded guanine tetrads and diverse loop structures. GQ sequence motifs are overrepresented in promoters, origins of replication, telomeres, and untranslated regions in mRNA, suggesting roles in modulating gene expression and preserving genomic integrity. Given these roles and unique aspects of different structures, GQs are attractive targets for drug design, but greater insight into GQ folding pathways and the interactions
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Kleiman, Diego E., Nawavi Naleem, and Serdal Kirmizialtin. "Exploring the Ion-Mediated RNA Interactions of a Helix-Junction-Helix RNA Model through Well-Tempered Metadynamics Simulations." Biophysical Journal 118, no. 3 (2020): 68a—69a. http://dx.doi.org/10.1016/j.bpj.2019.11.549.

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Dissertations / Theses on the topic "Ion-RNA Interactions"

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Okafor, Chiamaka Denise. "Metallobiochemistry of RNA: Mg(II) and Fe(II) in divalent binding sites." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53904.

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Cations are essential for ribonucleic acids (RNA), as they neutralize the negatively charged phosphate backbone. Divalent metals play important roles in the folding and function of RNA. The relationship between RNA and divalent cations magnesium (Mg(II)) and iron (Fe(II)) has been investigated. Mg(II) is involved in tertiary interactions of many large RNAs, and necessary for ribozyme activity. The influence of Mg(II) on RNA secondary and tertiary structure is investigated experimentally. Mg(II) binding to A-form RNA is accompanied by changes in CD spectra, indicating that Mg-RNA interactions
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Piccolo, Stefano. "Biophysical characterization of aptamer-ligand interactions by native mass spectrometry." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0276.

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Les aptamères sont des acides nucléiques capables de se lier sélectivement à un ligand ou à une famille de molécules. Les aptamères sont la partie sensible des riboswitches, qui sont des segments régulateurs de l'ARN messager impliqués dans l'expression génétique. Les aptamères ont aussi des applications prometteuses comme sondes artificielles et capteurs Pour ces technologies, il est crucial de comprendre comment la liaison se produit, de la quantifier, et de comprendre comment les changements conformationnels sont induits par les ligands. Les objectifs de cette thèse sont d'explorer l'applic
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Downey, Christopher Dale. "Metal ion dependence, thermodynamics, and kinetics of the GAAA tetraloop-receptor RNA tertiary interaction." Diss., Connect to online resource, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3239459.

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Brännvall, Mathias. "Metal ion cooperativity in Escherichia coli RNase P RNA." Doctoral thesis, Uppsala universitet, Institutionen för cell- och molekylärbiologi, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2056.

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RNase P is an essential ribonuclease responsible for removal of the 5’ leader of tRNA precursors. Bacterial RNase P consists of an RNA subunit and a small basic protein. The catalytic activity is associated with the RNA subunit, i.e. bacterial RNase P RNA is a ribozyme. The protein subunit is, however, essential for activity in vivo. RNase P RNA, as well as the holoenzyme, requires the presence of divalent metal ions for activity. The aim of this thesis was to increase our understanding of the catalytic mechanism of RNase P RNA mediated cleavage. The importance of the nucleotides close to the
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Yuan, Faqing. "RNA-metal ion interactions and metal ion- induced conformational change in the spliceosomal U2-U6 snRNA complex studied by lanthanide ion luminescence and resonance energy transfer techniques." 2008. http://etd.lib.fsu.edu/theses/available/etd-04122008-213549.

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Thesis (Ph. D.)--Florida State University, 2008.<br>Advisors: Nancy L. Greenbaum [and] Geoffrey F. Strouse, Florida State University, College of Arts and Sciences, Dept. of Chemistry & Biochemistry. Title and description from dissertation home page (viewed June 20, 2008). Document formatted into pages; contains xv, 120 pages. Includes bibliographical references.
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Mathews, Ryan. "Cleavage of an RNA analog by mononuclear zinc(II) macrocyclic complexes and metal ion and metallodrug interactions with deoxyribonucleic acids." 2008. http://proquest.umi.com/pqdweb?did=1594480911&sid=1&Fmt=2&clientId=39334&RQT=309&VName=PQD.

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Thesis (Ph.D.)--State University of New York at Buffalo, 2008.<br>Title from PDF title page (viewed on Jan. 22, 2009) Available through UMI ProQuest Digital Dissertations. Thesis adviser: Morrow, Janet R. Includes bibliographical references.
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Kumar, Sunil. "Metal Ion Mediated Riboswitch Folding and Cognate Ligand Sensing." Thesis, 2022. https://etd.iisc.ac.in/handle/2005/6007.

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Riboswitches are noncoding RNA molecules that can control gene expression upon cognate ligand binding. Riboswitches are primarily present in bacteria and are crucial for bacteria's survival, which makes riboswitches attractive targets for discovering new antimicrobials. Designing drugs that target a riboswitch function can be accelerated by understanding the effect of physicochemical factors (like ions, temperature, pressure, cosolvents, and pH) on the riboswitch folding and cognate ligand binding. The magnesium (Mg2+) ions possess the unique capability to exhibit site-specific binding along t
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Chiu, Wen-Chieh, та 邱玟潔. "Effect of Side Chain Length on Ion Pairing Interaction in β-Hairpin and Arginine Di-Methylation on RNA Recognition and Cellular Uptake". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/06565281535238628465.

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碩士<br>國立臺灣大學<br>化學研究所<br>101<br>Ion pairing interactions play important roles in protein stability and RNA recognition. Ion pairs are formed between a pair of oppositely charged amino acids. Interestingly, natural charged amino acids have different number of hydrophobic methylenes on their side chains. For negatively charged residues, Asp has one methylene and Glu has two methylenes. The analogous non-encoded negatively charged amino acid, Aad, contains three methylenes. To study the effect of negatively charged amino acid side chain length on cross strand ion pairs in β-sheets stability, a ba
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Cieplak-Rotowska, Maja. "Biophysical and molecular biology studies of proteins involved in gene silencing." Doctoral thesis, 2017. https://depotuw.ceon.pl/handle/item/2368.

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This thesis provides biophysical bases of the interactions between two proteins involved in microRNA (miRNA)-mediated silencing: CNOT1 and the silencing domain of GW182. The regulation of gene expression at the post-transcriptional level involves the crucial CCR4-NOT deadenylase complex, which deadenylates mRNA, and can also inhibit translation in an independent fashion. In miRNA-mediated silencing, the CCR4-NOT complex is brought into the vicinity of the target mRNA by the successive actions of the miRNA, the Argonaute protein and finally, the GW182 protein, which interacts directly with CCR4
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Books on the topic "Ion-RNA Interactions"

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Benarroch, Eduardo E. Neuroscience for Clinicians. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190948894.001.0001.

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The aim of this book is to provide the clinician with a comprehensive and clinical relevant survey of emerging concepts on the organization and function of the nervous system and neurologic disease mechanisms, at the molecular, cellular, and system levels. The content of is based on the review of information obtained from recent advances in genetic, molecular, and cell biology techniques; electrophysiological recordings; brain mapping; and mouse models, emphasizing the clinical and possible therapeutic implications. Many chapters of this book contain information that will be relevant not only
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Book chapters on the topic "Ion-RNA Interactions"

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Donghi, Daniela, and Roland K. O. Sigel. "Metal Ion–RNA Interactions Studied via Multinuclear NMR." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-545-9_16.

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Harris, Michael E. "Identification and Characterization of Metal Ion Coordination Interactions with RNA by Quantitative Analysis of Thiophilic Metal Ion Rescue of Site-Specific Phosphorothioate Modifications." In Handbook of RNA Biochemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2014. http://dx.doi.org/10.1002/9783527647064.ch14.

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Leipply, Desirae, Dominic Lambert, and David E. Draper. "Ion–RNA Interactions." In Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B. Elsevier, 2009. http://dx.doi.org/10.1016/s0076-6879(09)69021-2.

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DeRose, Victoria J., and Matthew V. Yglesias. "Metal Ion Interactions With DNA, RNA, and Nucleic Acid Enzymes." In Comprehensive Coordination Chemistry III. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-08-102688-5.00112-4.

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Goodenough, Ursula. "How Life Works." In The Sacred Depths of Nature, 2nd ed. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/oso/9780197662069.003.0005.

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Abstract The chapter’s Narrative outlines the core molecular dynamics of present-day organisms, with a consideration of DNA and RNA, protein structure and protein-protein interactions in three dimensions, enzymes as catalysts, the biophysics of membrane channels and ion gradients, biochemical cascades and signal transduction cascades, and cellular homeostasis. The chapter’s Reflections include a consideration of reductionism vs. holism. The “grunge theory of matter” is replaced by a paean to matter for all the incredible things it has achieved, followed by a consideration of the distress we may feel in considering our materiality and an invitation to invoke the spiritual practice of assent.
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Greenfeld, Max, and Daniel Herschlag. "Probing Nucleic Acid–Ion Interactions with Buffer Exchange-Atomic Emission Spectroscopy." In Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B. Elsevier, 2009. http://dx.doi.org/10.1016/s0076-6879(09)69018-2.

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Pabit, Suzette A., Kenneth D. Finkelstein, and Lois Pollack. "Using Anomalous Small Angle X-Ray Scattering to Probe the Ion Atmosphere Around Nucleic Acids." In Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B. Elsevier, 2009. http://dx.doi.org/10.1016/s0076-6879(09)69019-4.

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