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1

Cruz-Chu, Eduardo R., Aleksei Aksimentiev, and Klaus Schulten. "Ionic Current Rectification through Silica Nanopores." Journal of Physical Chemistry C 113, no. 5 (2009): 1850–62. http://dx.doi.org/10.1021/jp804724p.

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2

Wen, Chenyu, Shuangshuang Zeng, Shiyu Li, Zhen Zhang, and Shi-Li Zhang. "On Rectification of Ionic Current in Nanopores." Analytical Chemistry 91, no. 22 (2019): 14597–604. http://dx.doi.org/10.1021/acs.analchem.9b03685.

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3

Zhou, Yue, Xuewei Liao, Jing Han, Tingting Chen, and Chen Wang. "Ionic current rectification in asymmetric nanofluidic devices." Chinese Chemical Letters 31, no. 9 (2020): 2414–22. http://dx.doi.org/10.1016/j.cclet.2020.05.033.

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4

Karnik, Rohit, Chuanhua Duan, Kenneth Castelino, Hirofumi Daiguji, and Arun Majumdar. "Rectification of Ionic Current in a Nanofluidic Diode." Nano Letters 7, no. 3 (2007): 547–51. http://dx.doi.org/10.1021/nl062806o.

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5

Hou, Shengnan, Qinqin Wang, Xia Fan, Zhaoyue Liu, and Jin Zhai. "Alumina Membrane with Hour-Glass Shaped Nanochannels: Tunable Ionic Current Rectification Device Modulated by Ions Gradient." Journal of Nanomaterials 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/564694.

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A new alumina membrane with hour-glass shaped nanochannels is reported using the double-side anodization method and the subsequently in situ pore opening procedure, which is applied to develop the tunable ionic current rectification devices that were modulated by ions gradient. By regulating the pH gradient, tunable ionic current rectification properties which are mainly dependent on the asymmetric surface charge density or polarity distribution on the inner walls of the nanochannels can be obtained. The enhanced ionic current rectification properties were presented due to the synergistic effe
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6

Ma, Long, Zhongwu Li, Zhishan Yuan, Chuanzhen Huang, Zuzanna S. Siwy, and Yinghua Qiu. "Modulation of Ionic Current Rectification in Ultrashort Conical Nanopores." Analytical Chemistry 92, no. 24 (2020): 16188–96. http://dx.doi.org/10.1021/acs.analchem.0c03989.

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7

Yin, Xiaohong, Shudong Zhang, Yitong Dong, et al. "Ionic Current Rectification in Organic Solutions with Quartz Nanopipettes." Analytical Chemistry 87, no. 17 (2015): 9070–77. http://dx.doi.org/10.1021/acs.analchem.5b02337.

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8

Yan, Fei, Lina Yao, Qian Yang, Kexin Chen, and Bin Su. "Ionic Current Rectification by Laminated Bipolar Silica Isoporous Membrane." Analytical Chemistry 91, no. 2 (2018): 1227–31. http://dx.doi.org/10.1021/acs.analchem.8b04639.

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9

Ali, Mubarak, Saima Nasir, and Wolfgang Ensinger. "Bioconjugation-induced ionic current rectification in aptamer-modified single cylindrical nanopores." Chemical Communications 51, no. 16 (2015): 3454–57. http://dx.doi.org/10.1039/c5cc00257e.

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Aptamer–protein conjugation inside a confined environment generates a non-homogeneous fixed charge distribution, leading to the emergence of ionic current rectification characteristics in single cylindrical nanopores.
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10

Liu, Fei-Fei, Ye-Chang Guo, Wei Wang, Yu-Ming Chen, and Chen Wang. "In situ synthesis of a MOFs/PAA hybrid with ultrahigh ionic current rectification." Nanoscale 12, no. 22 (2020): 11899–907. http://dx.doi.org/10.1039/d0nr01054e.

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11

Chang, Fengxia, Cheng Chen, Xia Xie, Lisha Chen, Meixian Li, and Zhiwei Zhu. "A bidirection-adjustable ionic current rectification system based on a biconical micro-channel." Chemical Communications 51, no. 83 (2015): 15316–19. http://dx.doi.org/10.1039/c5cc05852j.

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We developed a simple, cheap and bidirectional ionic current rectification system based on the integration of a biconical micro-channel, working electrode and reference electrode. This system may have potential and realistic future value for studying two-way ionic transport in the cell membrane.
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12

Chander, Mukesh, Rajesh Kumar, Sushil Kumar, Narinder Kumar, and S. K. Chakarvarti. "Investigation of Ionic Transport Through Track-Etched Conical Nanopores of PET Membrane." Nano 13, no. 01 (2018): 1850011. http://dx.doi.org/10.1142/s179329201850011x.

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The control of ionic transportation inside the multi asymmetric conical nanopores in polyethylene terephthalate (PET) membrane was investigated. The conical nanopores were prepared by chemical etching in irradiated PET foil using etchant (9 M NaOH) and stopping solution (1 M NaCl [Formula: see text] 1 M HCOOH). The behavior of ionic current was recorded under stepping voltage [Formula: see text]2[Formula: see text]V to [Formula: see text]2[Formula: see text]V at different molar concentrations of potassium halides (KCl, KBr and KI) under symmetric bathing condition in electrochemical cell. It i
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13

Blundell, Emma L. C. J., Laura J. Mayne, Michael Lickorish, Steven D. R. Christie, and Mark Platt. "Protein detection using tunable pores: resistive pulses and current rectification." Faraday Discussions 193 (2016): 487–505. http://dx.doi.org/10.1039/c6fd00072j.

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We present the first comparison between assays that use resistive pulses or rectification ratios on a tunable pore platform. We compare their ability to quantify the cancer biomarker Vascular Endothelial Growth Factor (VEGF). The first assay measures the electrophoretic mobility of aptamer modified nanoparticles as they traverse the pore. By controlling the aptamer loading on the particle surface, and measuring the speed of each translocation event we are able to observe a change in velocity as low as 18 pM. A second non-particle assay exploits the current rectification properties of conical p
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14

Davis, Sebastian J., Michal Macha, Andrey Chernev, David M. Huang, Aleksandra Radenovic, and Sanjin Marion. "Pressure-Induced Enlargement and Ionic Current Rectification in Symmetric Nanopores." Nano Letters 20, no. 11 (2020): 8089–95. http://dx.doi.org/10.1021/acs.nanolett.0c03083.

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15

Liu, Shujuan, Yitong Dong, Wenbo Zhao, et al. "Studies of Ionic Current Rectification Using Polyethyleneimines Coated Glass Nanopipettes." Analytical Chemistry 84, no. 13 (2012): 5565–73. http://dx.doi.org/10.1021/ac3004852.

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16

Ai, Ye, Jing Liu, Bingkai Zhang, and Shizhi Qian. "Ionic current rectification in a conical nanofluidic field effect transistor." Sensors and Actuators B: Chemical 157, no. 2 (2011): 742–51. http://dx.doi.org/10.1016/j.snb.2011.05.036.

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17

Aaronson, Barak D. B., David Wigmore, Marcus A. Johns, Janet L. Scott, Igor Polikarpov, and Frank Marken. "Cellulose ionics: switching ionic diode responses by surface charge in reconstituted cellulose films." Analyst 142, no. 19 (2017): 3707–14. http://dx.doi.org/10.1039/c7an00918f.

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Cellulose films as well as chitosan-modified cellulose films of approximately 5 μm thickness, reconstituted from ionic liquid media onto a poly(ethylene-terephthalate) (PET, 6 μm thickness) film with a 5, 10, 20, or 40 μm diameter laser-drilled microhole, show significant current rectification in aqueous NaCl.
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18

Mádai, Eszter, Mónika Valiskó, and Dezső Boda. "Application of a bipolar nanopore as a sensor: rectification as an additional device function." Physical Chemistry Chemical Physics 21, no. 36 (2019): 19772–84. http://dx.doi.org/10.1039/c9cp03821c.

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In this nanopore sensor model selective binding of analyte ions (X) leads to the modulation of ionic current of the background electrolyte (KCl). Asymmetric charge pattern of the pore results in a dual response device (current and rectification).
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19

Poggioli, Anthony R., Alessandro Siria, and Lydéric Bocquet. "Beyond the Tradeoff: Dynamic Selectivity in Ionic Transport and Current Rectification." Journal of Physical Chemistry B 123, no. 5 (2019): 1171–85. http://dx.doi.org/10.1021/acs.jpcb.8b11202.

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20

Lin, Chih-Yuan, Jyh-Ping Hsu, and Li-Hsien Yeh. "Rectification of ionic current in nanopores functionalized with bipolar polyelectrolyte brushes." Sensors and Actuators B: Chemical 258 (April 2018): 1223–29. http://dx.doi.org/10.1016/j.snb.2017.11.172.

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21

Jung, Jaehoon, Jongyoung Kim, Kiwoon Choi, et al. "Fabrication and Ionic Current Rectification Characteristics of Biomimetic Aluminum Oxide Membrane." Membrane Journal 30, no. 3 (2020): 181–89. http://dx.doi.org/10.14579/membrane_journal.2020.30.3.181.

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22

So, Ju-Hee, Hyung-Jun Koo, Michael D. Dickey, and Orlin D. Velev. "Ionic Current Rectification in Soft-Matter Diodes with Liquid-Metal Electrodes." Advanced Functional Materials 22, no. 3 (2011): 625–31. http://dx.doi.org/10.1002/adfm.201101967.

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23

Alibakhshi, Mohammad Amin, Binqi Liu, Zhiping Xu, and Chuanhua Duan. "Geometrical control of ionic current rectification in a configurable nanofluidic diode." Biomicrofluidics 10, no. 5 (2016): 054102. http://dx.doi.org/10.1063/1.4962272.

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24

Ai, Ye, Mingkan Zhang, Sang W. Joo, Marcos A. Cheney, and Shizhi Qian. "Effects of Electroosmotic Flow on Ionic Current Rectification in Conical Nanopores." Journal of Physical Chemistry C 114, no. 9 (2010): 3883–90. http://dx.doi.org/10.1021/jp911773m.

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25

Cheng, Li-Jing, and L. Jay Guo. "Ionic Current Rectification, Breakdown, and Switching in Heterogeneous Oxide Nanofluidic Devices." ACS Nano 3, no. 3 (2009): 575–84. http://dx.doi.org/10.1021/nn8007542.

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26

Zheng, Ding-Cheng, and Li-Hsien Yeh. "Improved Rectification and Osmotic Power in Polyelectrolyte-Filled Mesopores." Micromachines 11, no. 10 (2020): 949. http://dx.doi.org/10.3390/mi11100949.

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Ample studies have shown the use of nanofluidics in the ionic diode and osmotic power generation, but similar ionic devices performed with large-sized mesopores are still poorly understood. In this study, we model and realize the mesoscale ionic diode and osmotic power generator, composed of an asymmetric cone-shaped mesopore with its narrow opening filled with a polyelectrolyte (PE) layer with high space charges. We show that, only when the space charge density of a PE layer is sufficiently large (>1×106 C/m3), the considered mesopore system is able to create an asymmetric ionic distributi
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27

Klink, R., and A. Alonso. "Ionic mechanisms for the subthreshold oscillations and differential electroresponsiveness of medial entorhinal cortex layer II neurons." Journal of Neurophysiology 70, no. 1 (1993): 144–57. http://dx.doi.org/10.1152/jn.1993.70.1.144.

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1. Layer II of the medial entorhinal cortex is composed of two electrophysiologically and morphologically distinct types of projection neurons: stellate cells (SCs), which are distinguished by rhythmic subthreshold oscillatory activity, and non-SCs. The ionic mechanisms underlying their differential electroresponsiveness, particularly in the subthreshold range of membrane potentials, were investigated in an "in vitro" slice preparation. 2. In both SCs and non-SCs, the apparent membrane input resistance was markedly voltage dependent, respectively decreasing or increasing at hyperpolarized or s
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28

Bush, Stevie N., Thomas T. Volta, and Charles R. Martin. "Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes." Nanomaterials 10, no. 3 (2020): 571. http://dx.doi.org/10.3390/nano10030571.

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Synthetic membranes containing asymmetrically shaped pores have been shown to rectify the ionic current flowing through the membrane. Ion-current rectification means that such membranes produce nonlinear current–voltage curves analogous to those observed with solid-state diode rectifiers. In order to observe this ion-current rectification phenomenon, the asymmetrically shaped pores must have pore-wall surface charge. Pore-wall surface charge also allows for electroosmotic flow (EOF) to occur through the membrane. We have shown that, because ion-current is rectified, EOF is likewise rectified i
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29

Kozak, J. Ashot, Hubert H. Kerschbaum, and Michael D. Cahalan. "Distinct Properties of CRAC and MIC Channels in RBL Cells." Journal of General Physiology 120, no. 2 (2002): 221–35. http://dx.doi.org/10.1085/jgp.20028601.

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In rat basophilic leukemia (RBL) cells and Jurkat T cells, Ca2+ release–activated Ca2+ (CRAC) channels open in response to passive Ca2+ store depletion. Inwardly rectifying CRAC channels admit monovalent cations when external divalent ions are removed. Removal of internal Mg2+ exposes an outwardly rectifying current (Mg2+-inhibited cation [MIC]) that also admits monovalent cations when external divalent ions are removed. Here we demonstrate that CRAC and MIC currents are separable by ion selectivity and rectification properties: by kinetics of activation and susceptibility to run-down and by p
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30

Ma, Tianji, Paulius Gaigalas, Mathilde Lepoitevin, et al. "Impact of Polyelectrolyte Multilayers on the Ionic Current Rectification of Conical Nanopores." Langmuir 34, no. 11 (2018): 3405–12. http://dx.doi.org/10.1021/acs.langmuir.8b00222.

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31

Zeng, Zhenping, Ye Ai, and Shizhi Qian. "pH-regulated ionic current rectification in conical nanopores functionalized with polyelectrolyte brushes." Phys. Chem. Chem. Phys. 16, no. 6 (2014): 2465–74. http://dx.doi.org/10.1039/c3cp54097a.

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32

Sun, Lei, Lin Zhou, Fei Yan, and Bin Su. "Ionic Strength Gated Redox Current Rectification by Ferrocene Grafted in Silica Nanochannels." Langmuir 35, no. 45 (2019): 14486–91. http://dx.doi.org/10.1021/acs.langmuir.9b02734.

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33

Jiang, Xikai, Ying Liu, and Rui Qiao. "Current Rectification for Transport of Room-Temperature Ionic Liquids through Conical Nanopores." Journal of Physical Chemistry C 120, no. 8 (2016): 4629–37. http://dx.doi.org/10.1021/acs.jpcc.5b11522.

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34

Hlushkou, Dzmitry, John M. Perry, Stephen C. Jacobson, and Ulrich Tallarek. "Propagating Concentration Polarization and Ionic Current Rectification in a Nanochannel–Nanofunnel Device." Analytical Chemistry 84, no. 1 (2011): 267–74. http://dx.doi.org/10.1021/ac202501v.

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35

Huang, Wei-Cheng, and Jyh-Ping Hsu. "Regulating the ionic current rectification behavior of branched nanochannels by filling polyelectrolytes." Journal of Colloid and Interface Science 557 (December 2019): 683–90. http://dx.doi.org/10.1016/j.jcis.2019.09.062.

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36

Alizadeh, Amer, Wei-Lun Hsu, Hirofumi Daiguji, and Moran Wang. "Temperature-regulated surface charge manipulates ionic current rectification in tapered nanofluidic channel." International Journal of Mechanical Sciences 210 (November 2021): 106754. http://dx.doi.org/10.1016/j.ijmecsci.2021.106754.

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37

Zhang, Shujie, Wei Chen, Laibo Song, et al. "Recent advances in ionic current rectification based nanopore sensing: a mini-review." Sensors and Actuators Reports 3 (November 2021): 100042. http://dx.doi.org/10.1016/j.snr.2021.100042.

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38

Fox, Jeffrey J., Jennifer L. McHarg, and Robert F. Gilmour. "Ionic mechanism of electrical alternans." American Journal of Physiology-Heart and Circulatory Physiology 282, no. 2 (2002): H516—H530. http://dx.doi.org/10.1152/ajpheart.00612.2001.

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Although alternans of action potential duration (APD) is a robust feature of the rapidly paced canine ventricle, currently available ionic models of cardiac myocytes do not recreate this phenomenon. To address this problem, we developed a new ionic model using formulations of currents based on previous models and recent experimental data. Compared with existing models, the inward rectifier K+ current ( I K1) was decreased at depolarized potentials, the maximum conductance and rectification of the rapid component of the delayed rectifier K+ current ( I Kr) were increased, and I Kr activation ki
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39

Kerschbaum, Hubert H., and Michael D. Cahalan. "Monovalent Permeability, Rectification, and Ionic Block of Store-operated Calcium Channels in Jurkat T Lymphocytes." Journal of General Physiology 111, no. 4 (1998): 521–37. http://dx.doi.org/10.1085/jgp.111.4.521.

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We used whole-cell recording to characterize ion permeation, rectification, and block of monovalent current through calcium release-activated calcium (CRAC) channels in Jurkat T lymphocytes. Under physiological conditions, CRAC channels exhibit a high degree of selectivity for Ca2+, but can be induced to carry a slowly declining Na+ current when external divalent ions are reduced to micromolar levels. Using a series of organic cations as probes of varying size, we measured reversal potentials and calculated permeability ratios relative to Na+, PX/PNa, in order to estimate the diameter of the c
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40

Sigg, Daniel M., Hsueh-Kai Chang, and Ru-Chi Shieh. "Linkage analysis reveals allosteric coupling in Kir2.1 channels." Journal of General Physiology 150, no. 11 (2018): 1541–53. http://dx.doi.org/10.1085/jgp.201812127.

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Potassium-selective inward rectifier (Kir) channels are a class of membrane proteins necessary for maintaining stable resting membrane potentials, controlling excitability, and shaping the final repolarization of action potentials in excitable cells. In addition to the strong inward rectification of the ionic current caused by intracellular blockers, Kir2.1 channels possess “weak” inward rectification observed in inside-out patches after prolonged washout of intracellular blockers. The mechanisms underlying strong inward rectification have been attributed to voltage-dependent block by intracel
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41

Guo, Zhijun, Jiahai Wang, Jiangtao Ren, and Erkang Wang. "pH-Reversed ionic current rectification displayed by conically shaped nanochannel without any modification." Nanoscale 3, no. 9 (2011): 3767. http://dx.doi.org/10.1039/c1nr10434a.

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42

Scruggs, Neal R., Joseph W. F. Robertson, John J. Kasianowicz, and Kalman B. Migler. "Rectification of the Ionic Current through Carbon Nanotubes by Electrostatic Assembly of Polyelectrolytes." Nano Letters 9, no. 11 (2009): 3853–59. http://dx.doi.org/10.1021/nl9020683.

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43

Miller, Scott A., Kathleen C. Kelly, and Aaron T. Timperman. "Ionic current rectification at a nanofluidic/microfluidic interface with an asymmetric microfluidic system." Lab on a Chip 8, no. 10 (2008): 1729. http://dx.doi.org/10.1039/b808179d.

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44

Alidoosti, Elaheh, and Hui Zhao. "The effects of electrostatic correlations on the ionic current rectification in conical nanopores." ELECTROPHORESIS 40, no. 20 (2019): 2655–61. http://dx.doi.org/10.1002/elps.201900127.

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45

Chein, Reiyu, and Bogan Chung. "Numerical study of ionic current rectification through non-uniformly charged micro/nanochannel systems." Journal of Applied Electrochemistry 43, no. 12 (2013): 1197–206. http://dx.doi.org/10.1007/s10800-013-0607-5.

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46

Chandler, S. H., C. F. Hsaio, T. Inoue, and L. J. Goldberg. "Electrophysiological properties of guinea pig trigeminal motoneurons recorded in vitro." Journal of Neurophysiology 71, no. 1 (1994): 129–45. http://dx.doi.org/10.1152/jn.1994.71.1.129.

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1. Intracellular recording and stimulation were made from guinea pig trigeminal motoneurons (TMNs) in brain stem slices. Electrophysiological properties were examined and the underlying currents responsible for motoneuron excitability were investigated by the use of current clamp and single electrode voltage clamp (SEVC) techniques. 2. The voltage responses to subthreshold hyperpolarizing or depolarizing current pulses showed voltage- and time-dependent inward rectification. SEVC analysis demonstrated that the hyperpolarizing inward rectification resulted from the development of a slowly occur
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47

Zhu, Xuanbo, Junran Hao, Bin Bao, et al. "Unique ion rectification in hypersaline environment: A high-performance and sustainable power generator system." Science Advances 4, no. 10 (2018): eaau1665. http://dx.doi.org/10.1126/sciadv.aau1665.

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The development of membrane science plays a fundamental role in harvesting osmotic power, which is considered a future clean and renewable energy source. However, the existing designs of the membrane cannot handle the low conversion efficiency and power density. Theory has predicted that the Janus membrane with ionic diode–type current would be the most efficient material. Therefore, rectified ionic transportation in a hypersaline environment (the salt concentration is at least 0.5 M in sea) is highly desired, but it still remains a challenge. Here, we demonstrate a versatile strategy for crea
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48

Kim, Yun Do, Seungwook Choi, Ansoon Kim, and Woo Lee. "Ionic Current Rectification of Porous Anodic Aluminum Oxide (AAO) with a Barrier Oxide Layer." ACS Nano 14, no. 10 (2020): 13727–38. http://dx.doi.org/10.1021/acsnano.0c05954.

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49

Şen, Mustafa, and Ali Demirci. "pH-Dependent ionic-current-rectification in nanopipettes modified with glutaraldehyde cross-linked protein membranes." RSC Adv. 6, no. 89 (2016): 86334–39. http://dx.doi.org/10.1039/c6ra19263g.

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50

Khatibi, Mahdi, Seyed Nezameddin Ashrafizadeh, and Arman Sadeghi. "Covering the conical nanochannels with dense polyelectrolyte layers significantly improves the ionic current rectification." Analytica Chimica Acta 1122 (July 2020): 48–60. http://dx.doi.org/10.1016/j.aca.2020.05.011.

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