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Journal articles on the topic 'IOP stabilization'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Sokolovskaya, T. V., A. A. Postolnik, and E. O. Krasnova. "Combination of nonpenetrating deep sclerectomy (NDPS) with vasoreconstructive surgery (VRS) in the treatment of glaucoma neuroopticopathy. Clinical observations. To the anniversary of Professor V.I. Kozlov (1930–1996)." Clinical cases in ophthalmology 9, no. 2 (2025): 43–49. https://doi.org/10.25276/2949-4494-2025-2-43-49.

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Relevance. Glaucoma remains a widespread pathology, occupying leading positions among the causes of blindness. To achieve stabilization of glaucoma process it is necessary to apply pathogenetically directed technologies. Purpose. To present the results of clinical observations confirming the effectiveness of the combination of non penetrating deep sclerectomy (NPSE) with vasoreconstructive surgery (VRS) in the treatment of glaucoma neurooptycopathy. Methods. This paper presents two clinical observations on the use of NGSE with VRO in the complex treatment of glaucoma neurooptycopathy in patien

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Amashova, U. L., A. V. Seleznev, and A. V. Kuroyedov. "Main morphofunctional correlations between indicators of intraocular pressure fluctuations and glaucomatous optic neuropathy progression." National Journal glaucoma 23, no. 4 (2024): 60–68. https://doi.org/10.53432/2078-4104-2024-23-4-60-68.

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According to established data, intraocular pressure (IOP) level is a substantiated risk factor for the development and progression of primary open-angle glaucoma. However, the progression of glaucoma despite achieving the 'controlled' IOP, as measured by traditional one- or two-time tonometry, has confirmed the possibility of other IOP characteristics that prevent the stabilization of the glaucomatous process.The review summarizes commonly used and describes newly emerging techniques for IOP monitoring, and analyzes studies that refute and confirm the presence of correlations between IOP fluct

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Vlasova, A. S., S. A. Petrov, E. V. Renzyak, and T. N. Malishevskaya. "Neuroprotective therapy of glaucoma." Russian Annals of Ophthalmology 141, no. 1 (2025): 83. https://doi.org/10.17116/oftalma202514101183.

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Glaucoma is a chronic multifactorial neurodegenerative disease; the most studied local risk factors for glaucoma progression are elevated intraocular pressure (IOP) and its diurnal fluctuations. However, normalization of IOP does not always guarantee stabilization of the glaucomatous process. This article reviews data from international and Russian studies on the pathophysiological mechanisms underlying the development and progression of glaucomatous optic neuropathy, and discusses current approaches to its therapeutic management.

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Voronin, G. V., M. K. Bersunkaev, and A. V. Volzhanin. "Influence of Phacoemulsification on Intraocular Pressure in Patients with Glaucoma." Ophthalmology in Russia 20, no. 4 (2023): 610–16. http://dx.doi.org/10.18008/1816-5095-2023-4-610-616.

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Phacoemulsification (PE) is a current ‘gold standard’ of the surgical treatment of the cataract. Apart from lens extraction and intraocular lens implantation, PE is accompanied by IOP changes in most cases. In cases of ophthalmic hypertension or primary open-angle glaucoma, IOP is most often decreased; however, the mechanism of this phenomenon is currently completely unknown. In closed-angle glaucoma, PE provides opening of the anterior chamber angle, which restores physiological outflow of intraocular fluid and leads to IOP stabilization. In some cases, however, PE may be accompanied by a sho

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Vera, Jesús, María Dolores Morenas-Aguilar, and Amador García-Ramos. "Evidence-Based Exercise Recommendations for the Reduction and Stabilization of Intraocular Pressure: A Practical Guide for Eye Care and Sport Specialists." Applied Sciences 15, no. 3 (2025): 1396. https://doi.org/10.3390/app15031396.

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The only proven method to manage glaucoma is the reduction and stabilization of intraocular pressure (IOP). A wide range of daily activities has been demonstrated to affect the IOP behavior, and eye care specialists should be aware of their effects for the prevention and treatment of glaucoma. Indeed, the impact of physical activity on IOP has gained attention in recent years, considering exercise prescription as a promising adjuvant strategy for controlling IOP in glaucoma patients. To integrate all the available information in this regard, we have conducted a clinical review based on a patie

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Kats, M. D., and A. V. Kuroyedov. "On the optimal values of «target» intraocular pressure." National Journal glaucoma 21, no. 3 (2022): 72–84. http://dx.doi.org/10.53432/2078-4104-2022-21-3-72-84.

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Current statistics show that glaucoma is the main cause of irreversible blindness worldwide. This fact generates continued interest in the search for new methods of rapid and accurate diagnosis of the disease. Presently, reducing the level of intra-ocular pressure (IOP) is the only proven strategy for slowing the progression of glaucomatous optic neuropathy. As such, achieving the so-called «target» pressure is the aim of any effective anti-glaucoma therapy. However, as practice shows, compensation of IOP does not always lead to stabilization of glaucoma progression. The concept of determining

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Gndoyan, Irina, Natalya Kuznetsova, and Alexander Derevyanchenko. "Progressive spectacle correction in patients with ametropia and primary open-angle glaucoma." Eye 125, no. 2019-1 (2019): 6–12. http://dx.doi.org/10.33791/2222-4408-2019-1-6-12.

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Purpose: To determine the role that progressive spectacle lenses play in intraocular pressure compensation and stabilization of the glaucomatous process in patients with primary open-angle glaucoma (POAG) combined with presbyopia and refractive errors. Material and methods. 29 patients (53 eyes) aged 43 to 67 years with I-II stage POAG and a certain type of refractive error were enrolled into study. All patients had intraocular pressure (IOP) compensated to the target level on medication. Patients of the main group (17 people, 32 eyes) used universal progressive spectacle lenses with optimized

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Jackson, Colette M., Michelle Nguyen, and Ronald Mancini. "Use of Cyanoacrylate Glue Casting for Stabilization of Periocular Skin Grafts and Flaps." Ophthalmic Plastic and Reconstructive Surgery 33, no. 3 (2017): 218–20. http://dx.doi.org/10.1097/iop.0000000000000827.

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Mahatma, Gina, Ama Sadaka, Shauna Berry, Amina Malik, and Andrew G. Lee. "Stabilization of Visual Function After Optic Nerve Sheath Fenestration for Optic Nerve Meningocele." Ophthalmic Plastic and Reconstructive Surgery 33, no. 6 (2017): e160-e161. http://dx.doi.org/10.1097/iop.0000000000000932.

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Voznyuk, A. P., S. I. Anisimov, S. Y. Anisimova, L. L. Arutyunyan, and N. S. Anisimova. "Application of femtolaser-assisted phacoemulsification in combined pathology of cataract and glaucoma." Modern technologies in ophtalmology, no. 2 (June 15, 2021): 18–21. http://dx.doi.org/10.25276/2312-4911-2021-2-18-21.

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Purpose. To evaluate the efficacy and safety of femtolaser-assisted phacoemulsification in glaucomatous eyes in the long-term follow-up. Materials and methods. A retrospective analysis of the results of the surgical treatment of patients with combined cataract and glaucoma pathology was analyzed. The patients were divided into groups depending on the method of surgical intervention: 1) phacoemulsification with femtolaser support (26 eyes, 23 patients); 2) phacoemulsification (36 eyes, 30 patients); Results. Before surgery, there were no statistically significant differences in IOP and corneal

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Kazantseva, А. Y., and O. A. Rumyantseva. "Surgical resection of the sclera is a non-penetrating operation for the treatment of patients with primary open-angle and secondary glaucoma." GlaucomaNews, no. 1 (January 20, 2020): 59–61. http://dx.doi.org/10.25276/2227-8281-1-59-61.

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Purpose. To evaluate the effectiveness of surgical resection of the sclera in patients with primary open-angle and secondary glaucoma. Materials and methods. The study included 84 patients with POAG and SG stages III-IV and decompensated IOP level (not higher than 32 mm Hg). In order to normalize the increased ophthalmotonus, a non - penetrating operation was performed-surgical resection of the sclera (SRS). The patients underwent complex ophthalmological examination and dynamic observation. Result. In the studied groups of patients after surgical treatment there was a decrease in elevated IOP

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Kazantseva, А. Y., and O. A. Rumyantseva. "Surgical resection of the sclera is a non-penetrating operation for the treatment of patients with primary open-angle and secondary glaucoma." GlaucomaNews, no. 1 (January 20, 2020): 62–65. http://dx.doi.org/10.25276/2227-8281-1-62-65.

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Purpose. To evaluate the effectiveness of surgical resection of the sclera in patients with primary open-angle and secondary glaucoma. Materials and methods. The study included 84 patients with POAG and SG stages III-IV and decompensated IOP level (not higher than 32 mm Hg). In order to normalize the increased ophthalmotonus, a non - penetrating operation was performed-surgical resection of the sclera (SRS). The patients underwent complex ophthalmological examination and dynamic observation. Result. In the studied groups of patients after surgical treatment there was a decrease in elevated IOP

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Cantarini, Mattia, Dario Rusciano, Rosario Amato, et al. "Structural Basis for Agonistic Activity and Selectivity toward Melatonin Receptors hMT1 and hMT2." International Journal of Molecular Sciences 24, no. 3 (2023): 2863. http://dx.doi.org/10.3390/ijms24032863.

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Glaucoma, a major ocular neuropathy originating from a progressive degeneration of retinal ganglion cells, is often associated with increased intraocular pressure (IOP). Daily IOP fluctuations are physiologically influenced by the antioxidant and signaling activities of melatonin. This endogenous modulator has limited employment in treating altered IOP disorders due to its low stability and bioavailability. The search for low-toxic compounds as potential melatonin agonists with higher stability and bioavailability than melatonin itself could start only from knowing the molecular basis of melat

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Tse, Brian C., Craig A. McKeown, and David T. Tse. "Titanium T-Plate as a Platform for Globe Stabilization in Acquired Nystagmus and Oscillopsia Without a Null Zone." Ophthalmic Plastic and Reconstructive Surgery 33, no. 3 (2017): e61-e63. http://dx.doi.org/10.1097/iop.0000000000000750.

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Myakonkaya, O. S., A. S. Sarkisyan, A. V. Seleznev, A. V. Kuroyedov, and I. R. Gazizova. "State-of-the-art of loading and unloading tests for glaucoma: potentialities and informative value." Russian Journal of Clinical Ophthalmology 21, no. 3 (2021): 153–58. http://dx.doi.org/10.32364/2311-7729-2021-21-3-153-158.

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Prevention of blindness and low vision resulting from the progression of glaucomatous optic neuropathy (GON) depends mainly on the early diagnosis of glaucoma. Loading and unloading tests which create conditions for intraocular pressure (IOP) fluctuations are important for the early diagnosis of glaucoma. Stress tests for glaucoma lead to a short-term IOP rise and help identify symptoms that are questionable under normal conditions. Stress tests include water-drinking test, position test, dark room test, dentation test, pharmacological mydriasis, corticosteroid provocative test, etc. Unloading

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Kholmatov, S. K. "About application of micropulse laser cyclocoagulation in glaucoma." Russian ophthalmology of children 51, no. 1 (2025): 44–50. https://doi.org/10.25276/2307-6658-2025-1-44-50.

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This review represents data on the mechanism of action and effectiveness of a promising and relatively new technique of transcleral laser cyclocoagulation in micropulse mode. Based on a detailed analysis of the effect of this intervention on the stabilization of the glaucoma process, visual acuity, as well as the frequency of complications, the author concludes that micropulse laser cyclocoagulation can be used in patients with refractory and angle-closure glaucoma with high visual functions. Author emphasizes that stabilization of IOP after micropulse laser cycloagulation is achieved more eas

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Kuleshova, N. A., O. V. Kolenko, and E. L. Sorokin. "Technical difficulties of adequate assessment of intraocular pressure in a patient with glaucoma in the long term after corneal refractive surgery (clinical case)." National Journal glaucoma 22, no. 1 (2023): 76–84. http://dx.doi.org/10.53432/2078-4104-2023-22-1-76-84.

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PURPOSE. To demonstrate a clinical case involving difficulties in adequate assessment of intraocular pressure (IOP) in a patient with glaucoma in the long term after LASIK.METHODS. The study describes the case of patient M. of 58 years old with complaints about decreased distance vision in the right eye during the last year. In 2004 the patient underwent LASIK for moderate myopia. In 2018, asymmetry in the parameters of optic nerve head (size of the optic cup to the optic disc ratio (C/D ratio) was revealed: in the right eye — up to 0.7, narrowing of the visual field from nasal to fixation poi

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18

Laroche, Daniel, Jessinta Oseni, Gideon Nkrumah, and Chester Ng. "Clear Lensectomy with Hydrus Stent in Black and Afro-Latino Patients: A 1-Year Retrospective Study." Journal of Ophthalmology 2022 (August 31, 2022): 1–7. http://dx.doi.org/10.1155/2022/8011745.

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Purpose. To determine the efficacy and safety of phacoemulsification, clear lensectomy, and the Hydrus microstent (Ivantis, Inc.) in Black and Afro-Latino glaucoma patients. Method. This is a retrospective nonrandomized study of 134 Black and Afro-Latino patients who underwent clear lensectomy with Hydrus stent implant for the treatment of glaucoma. For comprehensive analysis, patients were divided into mild, moderate, and advanced glaucoma. The evaluated parameters were reductions in the number of medications, intraocular pressure (IOP), mean deviation on visual field test, and visual acuity.

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Rasyda, Risnanda Putri, Nurwasis Nurwasis, and Dewi Rosarina. "Eye Emergency: A Case Report On Acute Primary Angle Closure." International Journal of Social Health 3, no. 5 (2024): 310–15. http://dx.doi.org/10.58860/ijsh.v3i5.189.

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Acute Primary Angle Closure (APAC) or Acute Glaucoma is a condition where intraocular pressure rapidly increases due to the occlusion of the trabecular meshwork by the iris. This case report aims to present the clinical manifestations of APAC and evaluate the initial treatment strategies to immediately reduce intraocular pressure (IOP) and prevent visual loss. A 63-year-old woman presented with a sudden onset of pain in her left eye, accompanied by redness, headache, blurred vision, and nausea. Her visual acuity in the left eye was 1/300, with an IOP of 69.3 mmHg. Slit-lamp examination reveale

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Semenov, E. D., A. A. Antonov, Kh Hadiri, and T. M. Aghajanyan. "Efficacy and safety of 0.1 % brimonidine as a starting monotherapy and when added to combination therapy of glaucoma." Russian Ophthalmological Journal 17, no. 4 (2024): 34–40. https://doi.org/10.21516/2072-0076-2024-17-4-34-40.

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Purpose: to analyze the efficacy and safety of Santabrim® as a starting monotherapy and when added to combination therapy for glaucoma.Material and methods. The study was conducted on 60 patients (60 eyes), including 21 (35 %) men and 39 (65 %) women, with initial or advanced primary open-angle glaucoma with moderately elevated IOP. The average age of patients was 63.4 years. The first group (30 eyes) consisted of patients who were prescribed Santabrim® 2 times a day as a starting monotherapy. The second group consisted of patients (30 eyes) who had an enhanced regimen using Santabrim® 2 times

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Fokin, V. P., S. V. Balalin, and A. S. Balalin. "Efficiency of brinzolamide and its combinations with timolol maleate in the treatment of primary open-angle glaucoma." National Journal glaucoma 20, no. 3 (2021): 78–85. http://dx.doi.org/10.53432/2078-4104-2021-20-3-78-85.

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PURPOSE. To evaluate the effectiveness of 1% brinzolamide solution (Brineks-M) and its combination with 0.5% timolol maleate solution (Brinarga) in the treatment of patients with primary open-angle glaucoma (POAG).METHODS. The study involved 56 patients (56 eyes) with initial or moderate POAG and normal or moderately increased intraocular pressure. Individually tolerated IOP, hydrodynamic parameters, hemodynamic parameters of the eye (by computer ophthalmoplethysmography), microcirculation (by OCT angiography of the optic nerve head) were determined during the study.RESULTS. The hypotensive ef

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Malishevskaya, T. N., T. N. Kiseleva, A. S. Vlasova, and E. K. Eliseeva. "Impact of combination of local carbonic anhydrase inhibitors and beta-blockers on intraocular pressure, visual functions and eye hemodynamics in primary open-angle glaucoma." Russian Ophthalmological Journal 14, no. 2 (2021): 96–102. http://dx.doi.org/10.21516/2072-0076-2021-14-2-96-102.

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Drug treatment optimization in primary open-angle glaucoma (POAG) is a topical issue of ophthalmology in recent decades. The review focuses on the choice of local hypotensive therapy and the effectiveness of a fixed combination (FC) of dorzolamide / timolol in glaucoma treatment. Since decreased perfusion eye pressure and disturbed regulation of local hemodynamics affect the development and progression of glaucomatous optical neuropathy, the use of anti-glaucomatous drugs or other hypotensive agents requires taking account of their effect on intraocular pressure (IOP), visual functions, and oc

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Petrov, Sergej Yu, Dzhamilya N. Lovpache, Igor' A. Loskutov, and Daria M. Safonova. "The influence of local IOP-lowering therapy on the anterior segment tissues and outcome of glaucoma filtering surgery." Ophthalmology journal 10, no. 4 (2017): 41–47. http://dx.doi.org/10.17816/ov10441-47.

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Nowadays, a wide choice of local IOP-lowering medications allows ensuring a successful intraocular pressure compensation and primary open angle glaucoma stabilization. However, taking into consideration a long term action of drugs on the ocular surface, even without clinical manifestations there is a direct inflammatory cells’ activation with mixed toxic and allergic changes, which is confirmed by histology, immune-histology, and impression cytology methods. Such chronic sub-clinical inflammation represent a potential risk of excessive fibroblast proliferation with subsequent rapid postoperati

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Rascheskov, A. Yu, I. A. Loskutov, A. V. Korneeva, A. F. Yafyasova, and S. S. Strakhova. "Antihypertensive therapy following glaucoma valve implantation: analysis of the effectiveness of carbonic anhydrase inhibitors and prostaglandin analogues." Meditsinskiy sovet = Medical Council, no. 13 (August 20, 2023): 229–37. http://dx.doi.org/10.21518/ms2023-255.

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Introduction. The Ahmed glaucoma valve (GV) type drainage implantation is characterized by high efficiency and low complication rate, and is finding an increasing application in clinical practice. Although GV provides better intraocular pressure (IOP) control and higher surgical success rates compared to trabeculectomy, the so-called hypertensive phase (HP), typically defined as an IOP elevation more than 21 mmHg, can occur at the period from one to three months postoperatively, related to the fibrous capsule reservoir formation, which does not have the character of persistent hypertension.Aim

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Laroche, Daniel, Gideon Nkrumah, and Chester Ng. "Real-world efficacy of the Hydrus microstent in Black and Afro-Latinx patients with glaucoma: a retrospective study." Therapeutic Advances in Ophthalmology 12 (January 2020): 251584142096431. http://dx.doi.org/10.1177/2515841420964311.

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Purpose: The purpose was to determine the real-world efficacy of phacoemulsification cataract surgery and Hydrus microstent in Black and Afro-Latinx patients with glaucoma. Methods: A retrospective noncomparative single-center study of 76 Black and Afro-Latinx patients with glaucoma who underwent phacoemulsification cataract surgery and Hydrus microstent placement for treatment of glaucoma at single practice. Investigated parameters were intraocular pressure (IOP), number of medications, mean deviation on visual field test, and visual acuity. Patients were also subgrouped into mild, moderate,

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Yozgat, Zübeyir. "Outcomes of 25-gauge pars plana vitrectomy using silicone oil versus C3F8 gas tamponades in rhegmatogenous retinal detachment." Kastamonu Medical Journal 5, no. 1 (2025): 70–75. https://doi.org/10.51271/kmj-0187.

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Aims: To compare the visual and anatomical outcomes, intraocular pressure (IOP) changes, and complications of 25-gauge pars plana vitrectomy (PPV) using silicone oil (SO) versus perfluoropropane (C3F8) gas tamponade in the management of rhegmatogenous retinal detachment (RRD). Methods: This retrospective study analyzed 43 eyes of 43 patients treated with 25-gauge PPV for RRD. Patients were divided into two groups: Group 1 (SO, n=25) and Group 2 (C3F8 gas, n=18). Visual acuity, IOP, and postoperative complications were evaluated over a 52-week follow-up period. Statistical comparisons were cond

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Tykhonchuk, N. A., N. K. Greben, I. D. Skrypnychenko, A. I. Zadorozhna, and I. V. Gavrylyak. "Efficiency of surgical treatment for complicated cataract: clinical and functional analysis." Archive of Ukrainian Ophthalmology 12, no. 3 (2025): 170–75. https://doi.org/10.22141/2309-8147.12.3.2024.392.

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Background. Despite the successes of ophthalmic surgery, the treatment of complicated cataract remains challenging due to concomitant conditions such as lens subluxation and glaucoma. The purpose of the study was to assess the clinical and functional state of the eye in patients with complicated cataract after lens extraction. Materials and methods. The study involved 54 patients: 36 with uncomplicated cataract (controls) and 18 (main group) with cataract complicated by primary open-angle glaucoma (POAG). They underwent an ophthalmic examination, including visometry, tonometry, echobiometry, a

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Sidorova, A. V., A. V. Starostina, M. A. Pecherskaia, and K. A. Stefankova. "Advantages of Micropulse Technology as a Method of Choice for the Treatment of Secondary Glaucoma in Patients with Corneal Diseases." Ophthalmology in Russia 19, no. 3 (2022): 515–23. http://dx.doi.org/10.18008/1816-5095-2022-3-515-523.

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Postkeratoplasty glaucoma develops after cornea transplantation in 10–53 % cases. For ophthalmotonus stabilization in patients, it was proposed to use micropulse laser surgery.Purpose. To evaluate the effectiveness of micropulse laser surgery in patients with secondary refractory glaucoma after keratoplasty.Patients and methods. The study included 27 eyes after different types of keratoplasty. The average level of intraocular pressure was 33.2 ± 3.7 mmHg, the average number of hypotensive drops was 2.9 ± 0.7. Visual acuity varied from incorrect light perception to 0.3 with correction. Micropul

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Anisimova, S. Yu, L. L. Arutyunyan, S. I. Anisimov, A. A. Bratchuk, and L. Pen. "Evaluation of the effectiveness of drainage surgery in young people with glaucoma." National Journal glaucoma 23, no. 2 (2024): 41–48. http://dx.doi.org/10.53432/2078-4104-2024-23-2-41-48.

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PURPOSE. To evaluate the efficacy of drainage surgery in primary juvenile open-angle glaucoma.METHODS. The study included 16 patients with glaucoma, they were examined at the East Sight Recovery eye care center. The mean age was 40.2±13.5 years. All patients underwent a standard ophthalmological examination, including additional methods in dynamics. All patients underwent non-penetrating deep sclerectomy (NPDS) with Xenoplast drainage. In two cases, a combined procedure was performed: NPDS and phacoemulsification with intraocular lens implantation (Phaco+IOL). Within a year after surgery, all

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Akioud, Wafae, Abderrahmane Hamzi, Mehdi Khmaily, Yassine Mozarie, and Abdelbare Oubaaz. "GlaucoMag Study: Does Magnesium Improve Patients with Primary Open Angle Glaucoma (POAG)?" European Journal of Medical and Health Sciences 4, no. 4 (2022): 50–53. http://dx.doi.org/10.24018/ejmed.2022.4.4.1373.

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Introduction: Primary open angle glaucoma (POAG) is a multi-factorial progressive optic neuropathy that results in gradual vision loss. Alongside an elevated intra ocular pressure (IOP), other factors influence the progression of retinal ganglion cells loss in POAG. Blood flow dysregulation and oxidative stress are believed to be important risk factors in the evolution of glaucomatous degenerative lesions. Magnesium is an essential cation for many reactions and enzyme activities in the human body. One of its crucial roles is vascular regulation and blood flow improvement by modifying endotheli

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Kuleshova, N. A., O. V. Kolenko, and E. L. Sorokin. "Features of diagnosing glaucoma in myopic eyes in the long term after keratorefractive surgery (clinical case)." Modern technologies in ophtalmology, no. 4 (September 29, 2023): 60–65. http://dx.doi.org/10.25276/2312-4911-2023-4-60-65.

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Purpose. Demonstration of a clinical case of diagnosis and dynamic observation of glaucoma in a patient after LASIK. Material and methods. Patient A., 58 years old. Complaints about decreasing in vision of the right eye into the distance during the last year. In 2004, LASIK was performed for moderate myopia with astigmatism. In 2018, for the first time, asymmetry of the parameters of the optic nerve head (the ratio of the maximum excavation size to the diameter of the disk (E/D)) was revealed for the first time: up to 0.7 in the right eye; on the left eye – up to 0.5. At the same time, the lev

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A.S., Sarkisyan, Balalin A.S., and Balalin S.V. "Complex technology of laser surgery for pigmentary glaucoma." Modern technologies in ophtalmology, no. 2 (June 15, 2021): 81–84. http://dx.doi.org/10.25276/2312-4911-2021-2-81-84.

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Purpose. To analyze the complex method effectiveness of pigmentary glaucoma laser surgery (YAG-laser iridectomy and a multistep SLT). Materials and methods. Laser iridectomy was performed in 14 patients (28 eyes) aged 13 to 54 years old with pigmentary glaucoma after achieving the values of the individual IOP level against the background of drug therapy. Then after 4 weeks SLT was carried out. If an exogenous pigmentation was ≥2 st., SLT repeated several times every 4-6 months. Observation period: from 4 to 15 years. Results. The glaucoma process stabilization was achieved in all cases. The le

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Kats, M. D., A. V. Kuroyedov, and M. A. Arkharov. "Changes in target IOP values in glaucoma patients depending on the number of surgical interventions they underwent." National Journal glaucoma 22, no. 1 (2023): 55–65. http://dx.doi.org/10.53432/2078-4104-2023-22-1-55-65.

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PURPOSE. To determine the optimal intraocular pressure (IOP) values that contribute to stabilization of the course of the disease in patients with different stages of primary open-angle glaucoma (POAG) before and after surgery, depending on the current state of ocular biomechanical parameters.METHODS. This analytical descriptive scientific-clinical study analyzes the results of diagnostic studies conducted in the period from 2019 to 2022. The final protocol included 137 patients (209 eyes) with different stages of POAG. Two groups of patients were identified: the main group (105 patients, 156

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Mędrzycka, Justyna, Paulina Szabelska, Magdalena Rerych, Radosław Różycki, and Joanna Gołębiewska. "Multimodal Imaging Techniques in Monitoring a Patient with Ocular Decompression Retinopathy." Diagnostics 13, no. 12 (2023): 1992. http://dx.doi.org/10.3390/diagnostics13121992.

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Ocular decompression retinopathy (ODR) is characterized by multiple retinal hemorrhages. It is a rare complication associated with rapid decrease of intraocular pressure (IOP). The course of ODR is usually asymptomatic and self-limiting, which was confirmed by the observation of our patient. In this study, we present a 5-month follow up of a 77-year-old woman with acute right eye (RE) filtration angle closure who developed symptoms of ODR. Clinical examination and multimodal imaging modalities, including color fundus photography, optical coherence tomography (OCT), OCT angiography (OCTA) and f

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Dang, Yalong, Susannah Waxman, Chao Wang, et al. "Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model." PeerJ 5 (August 14, 2017): e3629. http://dx.doi.org/10.7717/peerj.3629.

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Objective The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced by ablating cells with suicide gene therapy or saponin, which risks incomplete cell removal or dissolution of the extracellular matrix, respectively. We hypothesized that improved trabecular meshwork cell ablation would result from freeze-thaw cycles compared to chemical treatment. Materials and Methods We obtained 24 porcine eyes from

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Korchuganova, E. A., and A. Yu Kazantzeva. "Surgical stimulation of uveoscleral outflow is an alternative to cyclodestructive procedures." Russian Journal of Clinical Ophthalmology 21, no. 1 (2021): 9–13. http://dx.doi.org/10.32364/2311-7729-2021-21-1-9-13.

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Aim: to assess clinical efficacy and safety of surgical scleral rejection (SSR) vs. transscleral diode laser cyclophotocoagulation (TSCPC) in primary open-angle glaucoma (POAG) and secondary glaucoma (SG). Patients and Methods: study (prospective) group included 84 patients with POAG and SG after SSR. Control (retrospective) group included 80 patients after TSCPC. In addition, the patients were distributed by age and the stage and type of glaucoma, i.e., 128 patients were diagnosed with POAG and 36 patients were diagnosed with secondary thrombotic glaucoma. Follow-up was 24 to 36 months. IOP m

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Apostolova, Anastasiya Sergeevna. "A comparative study of Xalatan and Xalacom (Pfizer, USA) efficacy in the treatment of pseudoexfoliative glaucoma." Ophthalmology journal 6, no. 3 (2013): 71–74. http://dx.doi.org/10.17816/ov2013371-74.

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The purpose of this study was to compare the efficacy of Xalatan (Pfizer, USA) and Xalacom (Pfizer, USA) in pseudoexfoliative glaucoma therapy. We observed 41 patients (53 eyes) with PEG, 16 of them were men and 25 women. Treatment period was 24 months. The main group (20 patients, 28 eyes) instilled Xalatan, the comparison group (21 patients, 25 eyes) instillated Xalacom once before bedtime (8 p. m.). In the Xalatan group, IOP decreased from 23.75 ± 0.576 mm Hg at baseline to 18.93 ± 0.337 mm Hg at 6 Month visit, and increased again up to 22.00 ± 0,542 mm Hg by the end of 24 months period. In

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Erichev, V. P., V. S. Zinina, and A. V. Volzhanin. "Comparative study of the efficacy and safety of 0.005 % Glaumax and 0.005 % Xalatan." National Journal glaucoma 21, no. 3 (2022): 42–48. http://dx.doi.org/10.53432/2078-4104-2022-21-3-42-48.

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PURPOSE. To compare hypotensive efficiency and safety of generic latanoprost 0.005 % (Glaumax, “KEVELT AS”, Estonia) and original latanoprost 0.005 % (Xalatan, “Pfizer Inc”, USA) in glaucoma patients. METHODS. The study included patients with newly diagnosed primary open-angle glaucoma or patients with primary open-angle glaucoma on carbonic anhydrase inhibitor monotherapy 4 days after cease of treatment (the “wash-out” period). Study patients were divided into 2 groups. Group 1 consisted of 25 patients (30 eyes) with initial and advanced stages of newly diagnosed POAG and initial corneal-comp

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Sorrentino, Francesco Saverio, Claudio Bonifazzi, and Francesco Parmeggiani. "Diabetic macular edema: Safe and effective treatment with intravitreal triamcinolone acetonide (Taioftal)." PLOS ONE 16, no. 10 (2021): e0257695. http://dx.doi.org/10.1371/journal.pone.0257695.

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Purpose To suggest the safety and efficacy of preservative-free triamcinolone acetonide intravitreal injectable suspension (Taioftal) for the treatment of diabetic macular edema. Methods A prospective clinical study involved 49 patients (49 eyes), that were treated with Taioftal and followed-up for six months. Complete ophthalmic examination, including spectral domain optical coherence tomography, was performed at baseline, and at month 1, 3, 6 after the intravitreal injection. Accurate collection and analysis of best-corrected visual acuity (BCVA), central foveal thickness (CFT), intraocular

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Sokolovskaya, T. V., V. N. Gutnik, and Е. О. Krasnova. "Acute glaucoma attack in a patient recovered from coronavirus infection (case report)." National Journal glaucoma 22, no. 4 (2023): 52–59. http://dx.doi.org/10.53432/2078-4104-2023-22-4-52-59.

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The prevalence of ophthalmic manifestations in COVID-19 ranges from 2 to 32%. The most common ophthalmic disease associated with COVID-19 is viral conjunctivitis, but there are also reports of cases with episcleritis, uveitis, occlusions of the central retinal artery and vein, retinopathy, glaucoma, dry eye syndrome, as well as rare neuroophthalmological manifestations such as diplopia, ophthalmoplegia and nystagmus. This study reports a case of bilateral acute angle-closure glaucoma attack in a patient recovered from severe COVID-19 pneumonia.PURPOSE. To determine the causes of bilateral acut

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Абулкасимова, Х. Х., and М. Х. Каримова. "Improving Compliance in Patients with Open-Angle Glaucoma Using the Method of Self-Dependent Tonometry." Офтальмология. Восточная Европа, no. 2 (May 30, 2022): 251–59. http://dx.doi.org/10.34883/pi.2022.12.2.032.

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Цель. Повышение комплаенса у пациентов с открытоугольной глаукомой при помощи метода самостоятельной тонометрии с тонометром Icare HOME.Материалы и методы. В исследование были включены 36 пациентов с ПОУГ. В дальнейшем пациенты были разделены на 2 группы: основная группа включала 18 пациентов, у которых в процессе лечения проводилась интервенция с целью повышения комплаенса путем внедрения метода самостоятельного контроля ВГД с помощью тонометра Icare HOME; контрольная группа включала 18 пациентов, у которых в процессе наблюдения интервенции не проводилось. В работе для самостоятельной тономет

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Staff, Editorial. "TREX1 Mutations in Aicardi–Goutières Syndrome with Congenital Glaucoma." Precision Medicine Communications 3, no. 2 (2023): 83–86. http://dx.doi.org/10.55627/pmc.003.02.0482.

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Aicardi–Goutières syndrome (AGS) is a rare genetic disorder that primarily affects the brain, the skin, and the immune system. It is characterized by a group of symptoms that mimic the effects of a viral infection, leading to inflammation in various tissues. Świerczyńska and colleagues presented a case of a neonate with hypotrophy, microcephaly, frostbite-like skin lesions, thrombocytopenia, elevated liver enzymes, and hepatosplenomegaly and showed that she had ‘three prime repair exonuclease 1’ (TREX1) gene mutations. The genetic investigation found pathogenic mutations, c.490C>T and c.222

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Mogilevskyy, S. Yu, and A. V. Romaniuk. "Efficacy of new two-stage methods of surgical and laser treatment for primary open-angle glaucoma combined with cataract." Archive of Ukrainian Ophthalmology 12, no. 2 (2024): 121–27. http://dx.doi.org/10.22141/2309-8147.12.2.2024.381.

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Background. Lowering the intraocular pressure (IOP) is the only proven method to slow the progression of glaucomatous optic neuropathy. Successful conservative treatment or surgery do not guarantee the preservation of visual fields throughout life. Despite the current advances in conservative treatment of primary open-angle glaucoma, about 5.3 % of patients still require surgical or combined treatment. There is no consensus yet on approaches to the treatment of patients with glaucoma and cataract. The objective was to evaluate the effectiveness of new two-stage methods for surgical and laser t

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Muñoz-Pérez, Sócrates Pedro, Yoshida Mirella Gonzales-Pérez, and Tabita Elizabeth Pardo-Muñoz. "The use of Nanomaterials in the construction sector: A literary review." DYNA 89, no. 221 (2022): 101–9. http://dx.doi.org/10.15446/dyna.v89n221.100210.

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Currently, one of the methods to improve the properties of materials in construction is the use of nanomaterials. The objective of this paper is to review the technological advances in the application of nanomaterials, which improve mechanical properties when used in concrete, soils, pavements, among others. A total of 86 articles corresponding to the Scopus, Ebsco, Science Direc and IOP Science databases were reviewed. The studies show that with the application of nanomaterials, positive results are obtained in the improvement of the compressive and flexural strength of concrete, improvement

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Shvailikova, I. E., E. I. Belikova, and A. V. Korneeva. "The Results of Transscleral Diode Laser Cyclophotocoagulation in Micropulse Mode Treatment in Patients with Primary Subcompensated Open-Angle Glaucoma and Toxic-Allergic Syndrome of the Ocular Surface." Ophthalmology in Russia 18, no. 1 (2021): 77–82. http://dx.doi.org/10.18008/1816-5095-2021-1-77-82.

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Purpose: to analysis the results of microimpulse transscleral diode laser cyclophotocoagulation (DCPC) technique as a method of choice in patients with open-angle subcompensated glaucoma (OAG) with toxic allergic syndrome of the ocular surface (TASOS).Methods. The retrospective analysis of patients’ case reports with subcompensated open-angle glaucoma and TASOS was performed. Transscleral diode laser cyclophotocoagulation (DCPC) in a microimpulse mode was used in their treatment. A total of 19 patients’ case reports were analyzed.Results. In the postoperative period, its course, patient’s comp

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Eskina, E. N., A. V. Belogurova, and V. S. Zinina. "Effectiveness and tolerability of the fixed combination of preservative-free drugs timolol and travoprost in glaucoma patients after cataract surgery." National Journal glaucoma 22, no. 3 (2023): 45–51. http://dx.doi.org/10.53432/2078-4104-2023-22-3-45-51.

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PURPOSE. The aim of the study was to evaluate the tolerability and effectiveness of the preservative-free combination eye drops timolol 0,5%/travoprost (Travapress Duo, ROMPHARM Company) when changing therapy in patients with initial and moderate stages of glaucoma after phacoemulsification of age-related cataract.METHODS. The study included 38 patients with disorders of the ocular surface with specific complaints, initial and moderate stages of glaucoma compensated for therapy with β-blockers and prostaglandin F2-α analogues. The patients were using monodrugs of these groups, or their fixed c

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Das, Subrata Narayan, Susanta K. Biswal, and Ranjan K. Mohapatra. "Analysing the role of a bio-surfactant extracted from Colocasia esculenta (L.) Schott on the stabilization of high concentrated iron ore slurry for transportation." Bulletin of the Chemical Society of Ethiopia 37, no. 6 (2023): 1459–70. http://dx.doi.org/10.4314/bcse.v37i6.13.

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ABSTRACT. The transportation of minerals/ores in form of slurry through pipelines is an alternative, effective and also eco-friendly mode of transportation. Surfactants extracted from the plant sources are gaining high interest for the formulation and stabilization of high concentrated solid-water slurries. In this work, the role of a novel bio-surfactant extracted from Colocasia esculenta (L.) Schott on the stabilisation of iron ore slurry (IOS) was studied and reported first time. The collected iron ore powder (IOP) and dried IOS samples were analysed with the help of XRF, XRD, SEM and EDS a

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Dmitrieva, A. L., V. V. Myasnikova, R. A. Avakimyan, T. R. Hutim, and T. G. Zakaraiya. "Impact of angiogenesis inhibitors on the postoperative course of Ahmed valve implantation in patients with neovascular glaucoma." National Journal glaucoma 21, no. 4 (2022): 37–47. http://dx.doi.org/10.53432/2078-4104-2022-21-4-37-47.

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PURPOSE. To compare the course of the early postoperative period after Ahmed valve implantation in patients with neovascular glaucoma of diabetic and post-thrombotic genesis with and without anti-VEGF therapy.METHODS. This study included patients with refractory neovascular glaucoma of diabetic and post-thrombotic genesis who were indicated for Ahmed valve implantation. Some patients underwent intravitreal administration of ranibizumab 4–14 days prior to implantation. A total of 39 eyes from 39 patients were included in the study and divided into 2 groups: group 1 (n=20) — patients with refrac

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Ioshin, I. E., A. I. Tolchinskaya, I. V. Maksimov, et al. "Evaluation of repeated micropulse cyclophotocoagulation in patients with refractory glaucoma." National Journal glaucoma 20, no. 3 (2021): 30–39. http://dx.doi.org/10.53432/2078-4104-2021-20-3-30-39.

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PURPOSE. To evaluate the efficacy and safety of repeated micropulse transscleral cyclophotocoagulation (MP-TSCPC) in patients with previously operated refractory glaucoma.MATERIALS AND METHODS. We examined 89 patients aged 74.2±7.3 years with moderate (16), advanced (58) and terminal (15) stages of uncompensated primary openangle glaucoma (POAG) before and within 12 months after the first MP-TSCPC (SUPRA 810, “Quantel Medical”, France) using standard laser parameters — 100 J. Indications for repeated MP-TSCPC were determined for 23 patients in 3 (1 patient), 6 (14 patients), 9 (8 patients) mon

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Toptan, Muslum, and Omer Faruk Yilmaz. "Anterior segment parameters after trabeculectomy in pseudoexfoliation glaucoma versus primary open-angle glaucoma." Medical hypothesis discovery and innovation in ophthalmology 13, no. 2 (2024): 76–81. http://dx.doi.org/10.51329/mehdiophthal1497.

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Background: The effects of trabeculectomy on anterior segment parameters have been widely investigated. However, the stabilization time for various glaucoma types after trabeculectomy remains debatable. We investigated the effect of mitomycin C-augmented trabeculectomy on ocular anterior segment parameters in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG) during short-term follow-up using the Pentacam HR. Methods: In this retrospective observational study, consecutive patients diagnosed with medically uncontrolled POAG or PXG who underwent MMC-augmented trabeculectomy

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