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1

Neuhold, Erich, and Volker Turau. "Database research at IPSI." ACM SIGMOD Record 21, no. 1 (1992): 133–38. http://dx.doi.org/10.1145/130868.130886.

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Earl, A. N., and R. P. Whittington. "Capturing the semantics of an IPSE database." Data Processing 27, no. 9 (1985): 33–43. http://dx.doi.org/10.1016/0011-684x(85)90170-4.

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Kalaki, Niloufar Sadat, Mohammad Hossein Razizadeh, Fahimeh Safarnezhad Tameshkel, et al. "The breast cancer biomarkers associated with the development of the disease; an in-silico-based study." Immunopathologia Persa 11 (September 5, 2024): e41722. http://dx.doi.org/10.34172/ipp.2025.41722.

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Introduction: Breast cancer (BC) is among the top causes of mortality among women worldwide. Identifying genes by differential expression associated with the development of the disease helps us to better understanding the molecular mechanisms of BC. Objectives: Our study used in-silico analysis to identify hub genes could trigger the development of BC. Materials and Methods: We identified GSE38959 and GSE45827 for differentially expressed genes (DEGs) in the Gene Expression Omnibus (GEO) database, with an adjusted P<0.05. In both sets, logFC ≥ 2 and logFC ≤ -2 were observed in the DEGs that
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Vo, Quan Duy, Yukihiro Saito, Toshihiro Ida, Kazufumi Nakamura, and Shinsuke Yuasa. "The use of artificial intelligence in induced pluripotent stem cell-based technology over 10-year period: A systematic scoping review." PLOS ONE 19, no. 5 (2024): e0302537. http://dx.doi.org/10.1371/journal.pone.0302537.

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Background Stem cell research, particularly in the domain of induced pluripotent stem cell (iPSC) technology, has shown significant progress. The integration of artificial intelligence (AI), especially machine learning (ML) and deep learning (DL), has played a pivotal role in refining iPSC classification, monitoring cell functionality, and conducting genetic analysis. These enhancements are broadening the applications of iPSC technology in disease modelling, drug screening, and regenerative medicine. This review aims to explore the role of AI in the advancement of iPSC research. Methods In Dec
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Voso, M., S. Fenu, R. Latagliata, et al. "P-097 The revised IPSS predicts prognosis of myelodysplastic syndromes significantly better than IPSS and WPSS: Validation by the GROM database." Leukemia Research 37 (May 2013): S65—S66. http://dx.doi.org/10.1016/s0145-2126(13)70145-0.

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Khusna, Lailya, and Sitti Rahma Soleman. "Interprofessional Collaborative Practice Di Rumah." Zaitun (Jurnal Ilmu Kesehatan) 11, no. 2 (2023): 48. http://dx.doi.org/10.31314/zijk.v11i2.2515.

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Pendahuluan : Interprofesional education (IPE) merupakan suatu pendekatan yang melibatkan 2 atau lebih interprofesi kesehatan yang secara aktif berkontribusi dan berkolaborasi dalam memahami peran dan tanggung jawab profesi didalam area universitas yang selanjutnya berkembang didalam wilayah praktik melalui interprofesional education – collaboration practice (IPCP). IPE bertujuan untuk menyiapkan mahasiswa kesehatan didalamnya untuk mampu berkolaborasi secara terarah dengan interprofesi lain sedangkan (IPCP) diarea praktik klinik bertujuan untuk meningkatkan derajat kesehatan masyarakat sehat-
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Qin, Chuan, Yun Guo, De-Gang Yang, Ming-Liang Yang, Liang-Jie Du, and Jian-Jun Li. "Induced Pluripotent Stem Cell Transplantation Improves Locomotor Recovery in Rat Models of Spinal Cord Injury: a Systematic Review and Meta-Analysis of Randomized Controlled Trials." Cellular Physiology and Biochemistry 47, no. 5 (2018): 1835–52. http://dx.doi.org/10.1159/000491064.

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Background/Aims: Spinal cord injury (SCI) has long been a subject of great interest in a wide range of scientific fields. Several attempts have been made to demonstrate motor function improvement in rats with SCI after transplantation of induced pluripotent stem cells (iPSC). This systematic review and meta-analysis was designed to summarize the effects of iPSC on locomotor recovery in rat models of SCI. Methods: We searched the publications in the PubMed, Medline, Science Citation Index, Cochrane Library, CNKI, and Wan-fang databases and the China Biology Medicine disc. Results were analyzed
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Vo, Quan Duy, Yukihiro Saito, Kazufumi Nakamura, Toshihiro Iida, and Shinsuke Yuasa. "Induced Pluripotent Stem Cell-Derived Cardiomyocytes Therapy for Ischemic Heart Disease in Animal Model: A Meta-Analysis." International Journal of Molecular Sciences 25, no. 2 (2024): 987. http://dx.doi.org/10.3390/ijms25020987.

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Ischemic heart disease (IHD) poses a significant challenge in cardiovascular health, with current treatments showing limited success. Induced pluripotent derived–cardiomyocyte (iPSC-CM) therapy within regenerative medicine offers potential for IHD patients, although its clinical impacts remain uncertain. This study utilizes meta-analysis to assess iPSC-CM outcomes in terms of efficacy and safety in IHD animal model studies. A meta-analysis encompassing PUBMED, ScienceDirect, Web of Science, and the Cochrane Library databases, from inception until October 2023, investigated iPSC therapy effects
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Park, Sung-Ik. "Analysis of Correlation between Pollution Intensity and Trade Barrier using IPPS and GTAP Database." INTERNATIONAL BUSINESS REVIEW 3, no. 1 (1999): 129. http://dx.doi.org/10.21739/ibr.1999.12.3.1.129.

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Mumtaz, Dzakiyatul Fahmi. "The THE EFFECTIVENESS OF INTERPROFESSIONAL COLLABORATION PRACTICE IN OPERATING ROOM." Jurnal Keperawatan Respati Yogyakarta 8, no. 3 (2021): 208. http://dx.doi.org/10.35842/jkry.v8i3.636.

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Background: Interprofessional Collaboration Practice (IPCP) is a process when several different health care professionals provide comprehensive health services, working together with patients, patients' families, nurses (caregivers) and the community to provide excellent quality care. IPCP is a team-based care action that focuses on improving the quality of patient and family services but is still limited to being applied in hospitals, especially in the operating room.
 Aim: The purpose of this study was to determine the application of Interprofessional Collaboration Practice (IPCP) in th
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Meskarpour Amiri, Mohammad, Mohammadkarim Bahadori, Zahra Motaghed, and Ramin Ravangard. "Factors affecting informal patient payments: a systematic literature review." International Journal of Health Governance 24, no. 2 (2019): 117–32. http://dx.doi.org/10.1108/ijhg-01-2019-0006.

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Purpose Informal payments (IPs) for healthcare are a serious obstacle to equitable access and universal health coverage in developing countries. Policy makers need to know more about the hidden nature of informal patient payments (IPPs) before any policy adoption and implementation. The purpose of this paper is to systematically review the main factors affecting IPPs. Design/methodology/approach This systematic review was conducted in 2018 using the standard guideline of PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses. All English original articles on the determinant
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Tanabe, Shihori, Sabina Quader, Ryuichi Ono, et al. "Artificial Intelligence Approach in Machine Learning-Based Modeling and Networking of the Coronavirus Pathogenesis Pathway." Current Issues in Molecular Biology 47, no. 6 (2025): 466. https://doi.org/10.3390/cimb47060466.

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The coronavirus pathogenesis pathway, which consists of severe acute respiratory syndrome (SARS) coronavirus infection and signaling pathways, including the interferon pathway, the transforming growth factor beta pathway, the mitogen-activated protein kinase pathway, the apoptosis pathway, and the inflammation pathway, is activated upon coronaviral infection. An artificial intelligence approach based on machine learning was utilized to develop models with images of the coronavirus pathogenesis pathway to predict the activation states. Data on coronaviral infection held in a database were analy
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Govind, Nilay, Mrutyunjaya Sahoo, Sankar Suresh Kumar Pillai, and Suraj Kumar Sahu. "IPSD: e-repository of Permian seeds from Indian Lower Gondwana." Acta Palaeobotanica 63, no. 2 (2023): 151–61. http://dx.doi.org/10.35535/acpa-2023-0010.

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The interest and importance of studying the reproductive strategies of Palaeozoic plants are growing. Fossil seeds play an essential role in this line of study, as they are widely described from different sedimentary formations throughout the Permian period. The Indian Permian Seed Database (IPSD) software will be an information system for ensuring the storage, safety, accessibility and recovery of the details of Indian Permian seed records in a selective manner. The current database includes 28 genera and 44 species of compressed seeds described from Lower Gondwana (Permian), with all the det
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Indrianingsih, Sofiyah Tri. "INTERPROFESSIONAL COLLABORATION PRACTICE (IPCP) DALAM PEMBERDAYAAN MASYARAKAT." Zaitun (Jurnal Ilmu Kesehatan) 11, no. 1 (2023): 30. http://dx.doi.org/10.31314/zijk.v11i1.2937.

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Latar Belakang: Dewasa ini pembelajaran Interprofessional Collaboration Practice (IPCP) mampu menjadi media pemberdayaan masyarakat dalam peningkatan kualitas kesehatan di komunitas. Melalui Interprofessional Collaboration Practice (IPCP) dalam Pemberdayaan Masyarakat, harapannya peserta didik mampu untuk saling bersinergi dan mendukung terciptanya lingkungan masyarakat sehat di komunitas. Peserta didik akan saling bahu – membahu melaksanakan program kesehatan yang memaksimalkan kemampuan masyarakat. Pengembangan pembelajaran IPCP dalam pemberdayaan masyarakat ini perlu dipersiapkan dan dikemb
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Jazieh, Abdul-Rahman, Mark Riffon, Jennifer C. King, Gabrielle Betty Rocque, Electra D. Paskett, and Danielle M. Potter. "Disruptions to U.S. medical oncology care during the COVID-19 Pandemic: CancerLinQ Discovery (CLQD) analysis." Journal of Clinical Oncology 39, no. 15_suppl (2021): 6547. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.6547.

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6547 Background: The COVID-19 pandemic disrupted all facets of healthcare delivery including cancer care. This study evaluates the disruptions to US medical oncology practice during the pandemic in terms of number and type of patients (pts) encounters to determine the impact on continuity of patient care. Methods: We conducted a retrospective cohort analysis using the CLQD electronic health record database, containing data from 2+ million pts from all 50 states. We assessed changes in the monthly proportions of visit encounter types (in-person outpatient [IPOP] and telehealth [TE]) for new and
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Tung, Ying-Tsen, Chih-Lung Chen, Annie Yi-Ting Lai, et al. "Discovery of the Unique GMP-Grade iPSC Clones That Give Rise to Functional, High Purity, Matured CD8 Alpha Beta T or Gamma Delta T with Exponential Expansion Capacity." Blood 144, Supplement 1 (2024): 7195. https://doi.org/10.1182/blood-2024-203106.

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Although autologous cell therapy has shown remarkable clinical success and brought forth a medicinal revolution, significant hurdles remain. These include, but not limited to cell supply scarcity, prohibitively high costs stemming from the source material and manufacturing variabilities, lengthened and complex patient journey before receiving treatment, and the restrictive sites of manufacturing and therapeutic administration, creating formidable accessibility and affordability challenges. Many of the aforementioned issues central to successfully democratizing cell therapy could be ameliorated
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Madu, Yunita Gabriela, and Mery Solon. "Scoping Review: The Role of Personal Resilience and Personality Traits of Health Professionals In The Implementation of Interprofessional Collaboration Practice In Hospital." Journal of Nursing Science Update (JNSU) 11, no. 1 (2023): 54–62. http://dx.doi.org/10.21776/ub.jik.2023.011.01.7.

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Health workers have a major role in increasing public satisfaction and assessing the quality of hospital health services. To answer and get this, hospitals must pass the accreditation stage through the hospital accreditation committee, namely by having criteria for the National Hospital Accreditation Standard is Interprofessional Collaboration (IPCP) but challenges between fellow professions and from themselves because there is still autonomy from each profession. Autonomy is also a coping method health professionals use to overcome challenges. The purpose is to examine the role of personal re
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Ion, Daniel, Alexandra Bolocan, Ruxandra Sinescu-Baltateanu, et al. "Anatomic-surgical study on the interparietoperitoneal space from a laparo-endoscopic perspective." Romanian Journal of Military Medicine 125, no. 2 (2022): 202–5. http://dx.doi.org/10.55453/rjmm.2022.125.2.4.

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The interparietoperitoneal (IPP) space, by a broad definition, is the space between the musculo-fascial walls of the abdomen and the parietal peritoneum. A review of the literature on this subject has been performed through a search in the databases according to the following keywords: Bogros space, Retzius space, preperitoneal approach, and urogenital fascia. We have also analyzed the video recordings of the dissections of the inguinopreperitoneal region during TAPP, conducted by a single team, evaluating the dissection planes in the two compartments (medial and lateral) of the IPPS. Based on
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19

Lopes, Thiago Jambo Alves, Milena Simic, Gregory D. Myer, Kevin R. Ford, Timothy E. Hewett, and Evangelos Pappas. "The Effects of Injury Prevention Programs on the Biomechanics of Landing Tasks: A Systematic Review With Meta-analysis." American Journal of Sports Medicine 46, no. 6 (2017): 1492–99. http://dx.doi.org/10.1177/0363546517716930.

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Background: Anterior cruciate ligament (ACL) tear is a common injury in sports and often occurs during landing from a jump. Purpose: To synthesize the evidence on the effects of injury prevention programs (IPPs) on landing biomechanics as they relate to the ligament, quadriceps, trunk, and leg dominance theories associated with ACL injury risk. Study Design: Meta-analysis. Methods: Six electronic databases were searched for studies that investigated the effect of IPPs on landing task biomechanics. Prospective studies that reported landing biomechanics at baseline and post-IPP were included. Re
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Huang, Yu-Lun, Jaehun Jung, Colin M. S. Mulligan, Jaekeun Oh, and Marc F. Norcross. "A Majority of Anterior Cruciate Ligament Injuries Can Be Prevented by Injury Prevention Programs: A Systematic Review of Randomized Controlled Trials and Cluster–Randomized Controlled Trials With Meta-analysis." American Journal of Sports Medicine 48, no. 6 (2019): 1505–15. http://dx.doi.org/10.1177/0363546519870175.

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Background: Anterior cruciate ligament (ACL) injury prevention programs (IPPs) are generally accepted as being valuable for reducing injury risk. However, significant methodological limitations of previous meta-analyses raise questions about the efficacy of these programs and the extent to which meeting current best-practice ACL IPP recommendations influences the protective effect of these programs. Purpose: To (1) estimate the protective effect of ACL IPPs while controlling for common methodological limitations of previous meta-analyses and (2) systematically categorize IPP components and fac
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Bäckström, Martin. "Higher-Order Factors in a Five-Factor Personality Inventory and its Relation to Social Desirability." European Journal of Psychological Assessment 23, no. 2 (2007): 63–70. http://dx.doi.org/10.1027/1015-5759.23.2.63.

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Abstract. This paper compared two higher-order factor models using a 100-item, five-factor personality inventory originating from the IPIP database. The sample consisted of 2,019 subjects tested on the Internet. The two models were compared using confirmatory factor analysis. The two-factor model showed a similar fit to the data. The criteria for parsimony favored a hierarchical model with one higher-order factor at the top and five personality factors beneath. The single higher-order factor was found to be related to social desirability in a subsample of 196 subjects.
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Darwish, Toqa, Azhar Al-Khulaifi, Menatalla Ali, et al. "Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A meta-analysis." PLOS ONE 17, no. 8 (2022): e0272091. http://dx.doi.org/10.1371/journal.pone.0272091.

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Introduction Cystic fibrosis (CF) is a hereditary autosomal recessive disorder caused by a range of mutations in the CF Transmembrane Conductance Regulator (CFTR) gene. This gene encodes the CFTR protein, which acts as a chloride channel activated by cyclic AMP (cAMP). This meta-analysis aimed to compare the responsiveness of induced pluripotent stem cells (iPSCs) to cAMP analogues to that of commonly used animal models. Methods Databases searched included PubMed, Scopus, and Medline from inception to January 2020. A total of 8 and 3 studies, respectively, for animal models and iPSCs, were ana
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Amanulla, Safiya, Irin Saju, Sílvia Solé, et al. "Inappropriate Patient Sexual Behavior in Physiotherapy: A Systematic Review." Sustainability 13, no. 24 (2021): 13876. http://dx.doi.org/10.3390/su132413876.

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A behavior which is increasing in prevalence is sexual harassment initiated by a client and displayed towards the healthcare professionals and students of these healthcare-related professions. This is termed inappropriate patient sexual behaviour (IPSB). The consequences of IPSB can be significant, including decreased academic and work performance, decreased attention/concentration, reductions in work satisfaction, and a loss of confidence. The primary aim is to evaluate the literature on sexual harassment in physiotherapy. The secondary aim is to report on the incidence, situational factors,
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Park, Wungki, Geetha D. Vallabhaneni, Ludmila Katherine Martin, et al. "Clinicopathologic feature and outcome of appendiceal goblet cell carcinoid and neuroendocrine tumor." Journal of Clinical Oncology 30, no. 15_suppl (2012): e14170-e14170. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e14170.

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e14170 Background: Goblet cell carcinoid (GCC) of the appendix is a rare tumor comprising 5% of primary appendiceal tumors. GCC shares histological features of both neuroendocrine tumor (NET) and adenocarcinoma. Clinically, GCC also has an intermediate behavior between them. The management of GCC is mostly based on small retrospective series. We report the clinicopathological features, treatments, and outcomes of patients with appendiceal GCCs and NETs from a merged database between Emory University and the Ohio State University. Methods: We identified patients with appendiceal GCCs and NETs t
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Teymoori, Esmaeil, Vahid Rahmani, Arezo Elmi, et al. "Does the laparoscopic adrenalectomy seem to be less complicated for pheochromocytoma as a pathologic adrenal mass in children? A systematic review study." Immunopathologia Persa 6, no. 2 (2020): e20-e20. http://dx.doi.org/10.34172/ipp.2020.20.

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Introduction: This study was aimed to review the complications of the laparoscopic adrenalectomy for pheochromocytoma. Materials and Methods: International databases including PubMed, Web of Science and Scopus were considered for search of English articles by 24 May 2019. Seventeen published articles were finally entered into the study. Keywords were adrenalectomy, laparoscopy, chromaffin, PC12 cells, pheochromocytoma and children or a combination of them in the title and abstracts. Results: There were more than 647 individuals reviewed in this systematic review of 17 published articles consis
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Ghiasi, Nasrin, Rohollah Valizadeh, Mohammad Arabsorkhi, et al. "Efficacy and side effects of Sputnik V, Sinopharm and AstraZeneca vaccines to stop COVID-19; a review and discussion." Immunopathologia Persa 7, no. 2 (2021): e31-e31. http://dx.doi.org/10.34172/ipp.2021.31.

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We believe that vaccination is just a way to eliminate or strongly stop the COVID-19. In this regard, there are several vaccines with different efficacy and side effects. It is urgently required to have some efficient vaccines for the prevention and control of SARS-CoV-2. In this review, international databases were considered for searching relevant articles from 1 January 2020 to 1 May 2021. Keywords were COVID-19, novel coronavirus, 2019- nCoV, coronavirus disease 2019, vaccine, Sputnik V, Gamaleya, Gam-COVID-Vac, Sinopharm, BBIBP-CorV, AstraZeneca, Vaxzevria, Oxford, ChAdOx1 nCoV-19 and AZD
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Darakhshandeh, Ali, and Mahnaz Momenzadeh. "Cachexia and anorexia in cancer; a systematic review." Immunopathologia Persa 7, no. 2 (2020): e20-e20. http://dx.doi.org/10.34172/ipp.2021.20.

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The treatment strategy for cancer cachexia is based on the cachexia stage of the cancer and its phenotypes, therefore interventions and expected outcomes vary. In order for the patient to get the most out of the treatment, it should be done based on the mechanism of intervention and the quality of life of patients should be addressed, including aspects of rehabilitation and reduction of the patient’s suffering using a multidisciplinary team. Given the importance of the subject, the present study aims to investigate cachexia and anorexia in cancer. From the electronic databases, PubMed, Cochran
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Aguirre López, Luis José, and Tania Escalante. "Use of distribution models in the conservation of a Mexican endemic lagomorph." Therya 12, no. 3 (2021): 571–82. http://dx.doi.org/10.12933/therya-21-1088.

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The volcano rabbit (Romerolagus diazi), endemic to the central-eastern Transmexican Volcanic Belt, is one of the most threatened lagomorphs worldwide. Several factors threaten to decrease its geographical distribution, which is already restricted to the Pelado, Tláloc, Iztaccíhuatl, and Popocatépetl volcanoes. Our study aimed to propose priority areas for the conservation of this rabbit within Iztaccíhuatl-Popocatépetl National Park (IPNP) based on species distribution models. Volcano rabbit presence data were collected through different field sampling techniques and public and private databas
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Scheid, Christof, Liesbeth de Wreede, Anja van Biezen, et al. "The Revised IPSS (IPSS-R) At Transplant Predicts Overall and Relapse-Free Survival After Allogeneic Stem Cell Transplantation In MDS/sAML: A Retrospective Analysis Of The EBMT Chronic Malignancies Working Party." Blood 122, no. 21 (2013): 922. http://dx.doi.org/10.1182/blood.v122.21.922.922.

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Abstract Myelodysplastic syndromes are a heterogenous group of diseases with a very variable prognosis. Allogeneic stem cell transplantation is the only treatment modality offering the potential of cure, however its efficacy is counterbalanced by significant treatment-related morbidity and mortality. To assess the prognosis at diagnosis multiple predictive scoring systems have been developed, most recently a model based on cytogenetic features (Schanz et al. JCO 2012 30:820-829) and subsequently a revised International Prognostic Scoring System (IPSS-R) including the newly defined cytogenetic
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Walsh, Sabrina, Richard Clayton, Li Liu, and Sue Hodges. "Divergence in Contributing Factors for Suicide among Men and Women in Kentucky: Recommendations to Raise Public Awareness." Public Health Reports 124, no. 6 (2009): 861–67. http://dx.doi.org/10.1177/003335490912400614.

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Objectives. The primary purpose of this study was to compile demographic information from 1999 to 2005 on suicides and examine specifically toxicology differences between men and women dying by suicide and differences in what type of intimate partner problems (IPPs) were cited as a precipitating circumstance. Methods. In addition to death certificate data, coroner investigation reports were available for more than three-quarters of cases in 2005 detailing precipitating factors leading up to suicide. We linked toxicology results to death certificates and coroner investigation reports in the Ken
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Tran, Anna Thi Huyen, Paula Mandall, Ric Swindell, Peter Hoskin, David Bottomley, and James Wylie. "Biochemical outcomes for patients with intermediate-risk, organ-confined prostate cancer treated with I-125 interstitial brachytherapy monotherapy." Journal of Clinical Oncology 30, no. 5_suppl (2012): 192. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.192.

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192 Background: Treatment with low dose rate brachytherapy (LDR-BT) monotherapy is well established for low risk prostate cancer. The routine use of LDR-BT in intermediate risk (IR) is more controversial and is often combined with additional external beam radiotherapy (EBXRT). We report the biochemical outcome of a large cohort of patients with IR disease treated with LDR-BT monotherapy. Methods: A multi-institutional prospective database identified 615 patients with IR prostate cancer treated with I-125 interstitial BT between 2003–2007. IR was defined using Memorial Sloan-Kettering Cancer Ce
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Hajissa, Khalid, Md Asiful Islam, Abdoulie M. Sanyang, and Zeehaida Mohamed. "Prevalence of intestinal protozoan parasites among school children in africa: A systematic review and meta-analysis." PLOS Neglected Tropical Diseases 16, no. 2 (2022): e0009971. http://dx.doi.org/10.1371/journal.pntd.0009971.

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Introduction Parasitic infections, especially intestinal protozoan parasites (IPPs) remain a significant public health issue in Africa, where many conditions favour the transmission and children are the primary victims. This systematic review and meta-analysis was carried out with the objective of assessing the prevalence of IPPs among school children in Africa. Methods Relevant studies published between January 2000 and December 2020 were identified by systematic online search on PubMed, Web of Science, Embase and Scopus databases without language restriction. Pooled prevalence was estimated
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Fragopoulos, Anastasios, John Gialelis, and Dimitrios Serpanos. "Security Framework for Pervasive Healthcare Architectures Utilizing MPEG-21 IPMP Components." International Journal of Telemedicine and Applications 2009 (2009): 1–9. http://dx.doi.org/10.1155/2009/461560.

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Nowadays in modern and ubiquitous computing environments, it is imperative more than ever the necessity for deployment of pervasive healthcare architectures into which the patient is the central point surrounded by different types of embedded and small computing devices, which measure sensitive physical indications, interacting with hospitals databases, allowing thus urgent medical response in occurrences of critical situations. Such environments must be developed satisfying the basic security requirements for real-time secure data communication, and protection of sensitive medical data and me
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Masoud, Atousa, Mojtaba Akbari, Lida Jamal Ashini, et al. "The effects of MCC950 on NLRP3 inflammasome and inflammatory biomarkers: a systematic review and meta-analysis on animal studies." Immunopathologia Persa 11 (February 25, 2025): e43847. https://doi.org/10.34172/ipp.2025.43847.

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Introduction: The NLRP3 inflammasome plays a key role in the regulation of inflammation and has been implicated in various inflammatory diseases. The present study evaluated the impact of MCC950 on NLRP3 and inflammatory biomarkers in systematic review and meta-analysis. Methods: Searches were performed across databases including Medline (PubMed), Scopus, Web of Science, and Embase. The pooled effects of MCC950 on NLRP3, TNF-alpha, interleukin (IL)-16, IL-18, and IL-1β were analyzed using a random effects model. Results: Twenty animal studies met the inclusion criteria. MCC950 did not signific
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Da Cruz Fontes, Bruna Maria, and Cleide Barbieri de Souza. "Células-Tronco Pluripotentes Induzidas (iPSC) na Modelagem do Transtorno do Espectro Autista (TEA)." Ensaios e Ciência C Biológicas Agrárias e da Saúde 25, no. 5-esp. (2022): 619–27. http://dx.doi.org/10.17921/1415-6938.2021v25n5-esp.p619-627.

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O Transtorno do Espectro Autista (TEA) se caracteriza pela manifestação de déficits persistentes na comunicação e interação social associados aos padrões restritos e repetitivos de comportamentos, interesses ou atividades. Sua prevalência demonstrou crescimento nos últimos anos, em 2000 era de 1 em 150 crianças, alcançando, em 2016, estimativas de 1 em 54 crianças diagnosticadas, estimulando a busca pela identificação de aspectos biológicos em âmbito molecular do transtorno. Com o advento das células-tronco pluripotentes induzidas (iPSC), através da reprogramação de células somáticas, tornou-s
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Niemis, Wasiri, Shenita R. Peterson, Chrisabella Javier, Amy Nguyen, Sanchi Subiah, and Rohan H. C. Palmer. "On the utilization of the induced pluripotent stem cell (iPSC) model to study substance use disorders: A scoping review protocol." PLOS ONE 18, no. 10 (2023): e0292238. http://dx.doi.org/10.1371/journal.pone.0292238.

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Introduction Induced pluripotent stem cells (iPSCs) are cells derived from somatic cells via reprogramming techniques. The iPSC approach has been increasingly used in neuropsychiatric research in the last decade. Though substance use disorders (SUDs) are a commonly occurring psychiatric disorder, the application of iPSC model in addiction research has been limited. No comprehensive review has been reported. We conducted a scoping review to collate existing evidence on the iPSC technologies applied to SUD research. We aim to identify current knowledge gaps and limitations in order to advance th
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Tsujimoto, Hiraku, Naoko Katagiri, Yoshihiro Ijiri, et al. "In vitro methods to ensure absence of residual undifferentiated human induced pluripotent stem cells intermingled in induced nephron progenitor cells." PLOS ONE 17, no. 11 (2022): e0275600. http://dx.doi.org/10.1371/journal.pone.0275600.

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Cell therapies using human induced pluripotent stem cell (hiPSC)-derived nephron progenitor cells (NPCs) are expected to ameliorate acute kidney injury (AKI). However, using hiPSC-derived NPCs clinically is a challenge because hiPSCs themselves are tumorigenic. LIN28A, ESRG, CNMD and SFRP2 transcripts have been used as a marker of residual hiPSCs for a variety of cell types undergoing clinical trials. In this study, by reanalyzing public databases, we found a baseline expression of LIN28A, ESRG, CNMD and SFRP2 in hiPSC-derived NPCs and several other cell types, suggesting LIN28A, ESRG, CNMD an
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Gara, Sudheer Kumar, Haitao Wang, Anand Singh, et al. "Abstract 5445: Unravelling the molecular mechanisms of stemness in small cell lung cancer using an iPSC-based approach." Cancer Research 84, no. 6_Supplement (2024): 5445. http://dx.doi.org/10.1158/1538-7445.am2024-5445.

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Abstract Introduction: The cancer stem cell hypothesis explains the heterogeneity, drug resistance, and metastatic potential of Small Cell Lung Cancer (SCLC). To address limited surgical tissue availability, we developed an induced pluripotent stem cell (iPSC) model for investigating SCLC stemness mechanisms and potential novel therapies. Cigarette smoke condensates (CSC) have previously been linked to stem cell activation in lung epithelial cells. We aimed to transform normal lung iPSCs (Lu-iPSC) through prolonged CSC exposure to identify candidate genes in the transition to cancer stem cells
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Voso, Maria Teresa, Susanna Fenu, Roberto Latagliata, et al. "Revised International Prognostic Scoring System (IPSS) Predicts Survival and Leukemic Evolution of Myelodysplastic Syndromes Significantly Better Than IPSS and WHO Prognostic Scoring System: Validation by the Gruppo Romano Mielodisplasie Italian Regional Database." Journal of Clinical Oncology 31, no. 21 (2013): 2671–77. http://dx.doi.org/10.1200/jco.2012.48.0764.

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Purpose The definition of disease-specific prognostic scores plays a fundamental role in the treatment decision-making process in myelodysplastic syndrome (MDS), a group of myeloid disorders characterized by a heterogeneous clinical behavior. Patients and Methods We applied the recently published Revised International Prognostic Scoring System (IPSS-R) to 380 patients with MDS, registered in an Italian regional database, recruiting patients from the city of Rome (Gruppo Romano Mielodisplasie). Patients were selected based on the availability of IPSS-R prognostic factors, including complete per
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Sorogina, D. A., E. V. Grigor’eva, A. A. Malakhova та ін. "Creation of Induced Pluripotent Stem Cells ICGi044-B and ICGi044-C Using Reprogramming of Peripheral Blood Mononuclear Cells of a Patient with Parkinson’s Disease Associated with <i>с.1492T&gt;G</i> Mutation in the <i>GLUD2</i> Gene". Онтогенез 54, № 1 (2023): 114–22. http://dx.doi.org/10.31857/s0475145023010123.

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Parkinson’s disease is a multifactorial disease; both genetic predisposition (5% of all cases), environmental factors and age-related changes in the brain and other body systems contribute to its etiology. For the diagnosis and study of the pathology of the development of the disease, it is important to search for new polymorphisms associated with hereditary forms of the disease. We analyzed the clinical exome of a 55-year-old patient with Parkinson’s disease and identified a single nucleotide polymorphism in the GLUD2 gene (c.1492TG). This genetic variant is pathogenic according to the ClinVa
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Ghorbani Doshantapeh, Anna, Mayyadah Hameed Rashid, Raed Muslim Mhaibes, et al. "Systematic review and meta-analysis of the association between gallstones and cholecystectomy with liver cancer." Immunopathologia Persa 11 (September 17, 2024): e40666. http://dx.doi.org/10.34172/ipp.2025.40666.

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Introduction: Cholelithiasis and related treatments are associated with several gastrointestinal cancers. Thus, the present systematic review and meta-analysis aimed to investigate the relationship between cholelithiasis and cholecystectomy with the risk of liver cancer. Materials and Methods: The present study is a systematic review and meta-analysis conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We performed a search on the databases of Web of Science, Cochrane, ProQuest, PubMed, and Google Scholar until January 21, 2024. Moreover, the statis
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Hussein, Kebede, Animesh D. Pardanani, Daniel van Dyke, Curtis A. Hanson, and Ayalew Tefferi. "IPSS-Independent Cytogenetic Risk Categorization in Primary Myelofibrosis." Blood 114, no. 22 (2009): 2909. http://dx.doi.org/10.1182/blood.v114.22.2909.2909.

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Abstract Abstract 2909 Poster Board II-885 Background: Previous studies have identified sole abnormalities of del(20q) and del(13q) as prognostically favorable cytogenetic markers in primary myelofibrosis (PMF) (Tefferi et al. BJH 2001;113:763). A more recent study (Tam et al. Blood 2009;113:4171) confirmed these findings and suggested additional cytogenetic markers of prognosis. In the current study with larger numbers of informative patients studied at time of diagnosis, we wanted to validate these observations and examine the prognostic interaction between cytogenetic risk categorization an
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Mollazadeh, Hanieh, and Mansour Salesi. "A systematic review and meta-analysis of the association between selenium and osteoarthritis." Immunopathologia Persa 11 (August 31, 2024): e40656. http://dx.doi.org/10.34172/ipp.2025.40656.

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Introduction: Osteoarthritis is an inflammatory disorder and the most common human joint disease. Considering the anti-inflammatory properties of selenium, we aimed to investigate the relationship between selenium and the risk of osteoarthritis in this study. Materials and Methods: The present study was a systematic review and meta-analysis based on the PRISMA guidelines, conducted in databases including Web of Science, Cochrane, ProQuest, PubMed, and Google Scholar Search Engine for articles published until December 12, 2023. Data was analyzed using STATA 14 software, and tests with p-values
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Mohammadzadeh, Elham, Razieh Bagheri Shahzadeh Aliakbari, Atieh Nouralishahi, et al. "A systematic review and meta-analysis investigating the association between constipation and colorectal cancer." Immunopathologia Persa 10, no. 2 (2024): e40617. http://dx.doi.org/10.34172/ipp.2024.40617.

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Introduction: Colorectal cancer (CRC) ranks as the third most prevalent diagnosed tumor worldwide. While the association between constipation and certain tumors has been established, our study aims to examine the relationship between constipation and colorectal tumors. Materials and Methods: This study employed a systematic review and meta-analysis following the PRISMA reporting guidelines. Searches were conducted without time restrictions until November 4, 2023, across various databases, including PubMed, Scopus, Web of Science, Cochrane, and the Google Scholar search engine. Data analysis wa
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Yazdizadeh, Vahideh, Ziba Taghizadeh, Maryam Farmahini Farahani, Mehrandokht Nekavand, and Zeinab Abbasi. "Is AIDS related to social determinants of health in Iran? A systematic review." Immunopathologia Persa 6, no. 1 (2020): e13-e13. http://dx.doi.org/10.15171/ipp.2020.13.

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Introduction: AIDS is a global challenge. By looking deeper into the nature of AIDS and its transmission, it can be concluded that AIDS is a social phenomenon rather than a completely biological disease and the results of studies show a significant relationship between the risk of HIV infection and some underlying factors such as demographic, social, economic and cultural factors. Today, these structural and social factors are known as social determinants of health (SDH). The current systematic study aimed to identify SDH related to AIDS in Iran, in order to adopt appropriate strategies to pre
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Abbasi, Sheida, Jalal Rezaei, Fariba Bazi, et al. "Association between metabolic syndrome and risk of endometrial cancer; a systematic review and meta-analysis." Immunopathologia Persa 11 (November 25, 2024): e41724. https://doi.org/10.34172/ipp.2025.41724.

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Introduction: Endometrial cancer is one of the most prevalent female malignancies, with various factors, including metabolic syndrome, contributing to its incidence. Thus, this study aims to evaluate the association between metabolic syndrome and the risk of endometrial carcinoma. Materials and Methods: In this systematic review and meta-analysis, two independent authors searched electronic databases, including Cochrane, PubMed, ProQuest, Web of Science, and the Google Scholar search engine up to May 16, 2024. Data analysis was conducted using STATA 14 software with a significance level of P &
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Kharazmi, Amir Behnam, Sajad Ataei Azimi, Atefeh Nourmohammadi, et al. "Association between rheumatoid arthritis and lung neoplasm; a systematic review and meta-analysis." Immunopathologia Persa 11 (February 6, 2025): e43792. https://doi.org/10.34172/ipp.2025.43792.

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Introduction: Lung cancer is one of the most common malignancies in patients with rheumatoid arthritis (RA). Therefore, this study aimed to determine the association between RA and lung neoplasm using a systematic review and meta-analysis. Materials and Methods: This research was conducted according to the PRISMA guidelines. The databases ProQuest, PubMed, Embase, Web of Science, Cochrane, Scopus, and the search engine Google Scholar were searched up to October 8, 2024. Data analysis was performed using STATA 14 software, and P&lt;0.05 was considered statistically significant. Results: A total
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Adnan Abdullkareem, Fatma, Sara Teihou Jorshari, Abdul Amir Kadhum, et al. "Relationship between gallstone and biliary tract neoplasm; a systematic review and meta-analysis of cohort and case-control studies." Immunopathologia Persa 11 (December 7, 2024): e40680. https://doi.org/10.34172/ipp.2025.40680.

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Introduction: As a common disease, gallstone has the potential to increase the risk of biliary tract neoplasm via inflammation, bile flow alterations, or changing the levels of metabolic hormones. Objectives: The present systematic review intended to investigate the potential relationship between gallstone and biliary tract neoplasm. Materials and Methods: The present study was conducted through a systematic review and meta-analysis, based on the guidelines provided by PRISMA. A comprehensive search was performed in the Web of Science, Cochrane, ProQuest, PubMed, and Google Scholar databases u
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Quddus, F., A. Ahmed, S. Naqvi, et al. "Validation of IPSS criteria in more than 1,600 MDS patients." Journal of Clinical Oncology 25, no. 18_suppl (2007): 7079. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7079.

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7079 Myelodysplastic syndromes (MDS) are a diverse group of clonal stem cell disorders characterized by bone marrow failure, dysmyelopoiesis and peripheral cytopenias and affecting predominantly an elderly population. The International Prognostic Scoring System (IPSS) incorporates the number of peripheral cytopenias, percentage of bone marrow blasts and chromosomal abnormalities and assigns a score to predict survival and risk of disease progression to AML. Using the extensive MDS database at the University of Massachusetts we analyzed survival time in relation to IPSS scoring and also its var
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Lovtang, Sara C. P., and Gregg M. Riegel. "Predicting the Occurrence of Downy Brome (Bromus tectorum) in Central Oregon." Invasive Plant Science and Management 5, no. 1 (2012): 83–91. http://dx.doi.org/10.1614/ipsm-d-11-00029.1.

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AbstractWhere the nonnative annual grass downy brome proliferates, it has changed ecosystem processes, such as nutrient, energy, and water cycles; successional pathways; and fire regimes. The objective of this study was to develop a model that predicts the presence of downy brome in Central Oregon and to test whether high presence correlates with greater cover. Understory data from the U.S. Department of Agriculture (USDA) Forest Service's Current Vegetation Survey (CVS) database for the Deschutes National Forest, the Ochoco National Forest, and the Crooked River National Grassland were compil
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