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Journal articles on the topic 'IRIS staging'

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1

Chen, Fanfan. "From the Experiences of the Mountains and the Seas to the Experiments of Alchemy." IRIS, no. 35 (June 30, 2014): 49–64. http://dx.doi.org/10.35562/iris.1736.

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This essay explores the Chinese imagination and “logic” that construct both literal and figurative ways of ascending to heaven from the mythic or imaginary facts to the pragmatic and spiritual practice. Many Taoist philosophers and alchemists draw on figurative language and allegories to demonstrate abstract notions and wisdom. This figurative mediation is reminiscent of Plato’s approach in staging Socrates as a “teller of myth”. The present study thus resorts to the theory of the imaginary to better illuminate the underlying symbolism and the universal imaginary in Chinese texts and thought.
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Perondi, Francesca, Ilaria Lippi, Veronica Marchetti, Barbara Bruno, Antonio Borrelli, and Simonetta Citi. "How Ultrasound Can Be Useful for Staging Chronic Kidney Disease in Dogs: Ultrasound Findings in 855 Cases." Veterinary Sciences 7, no. 4 (2020): 147. http://dx.doi.org/10.3390/vetsci7040147.

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In patients affected by chronic kidney disease (CKD), some ultrasonographic (US) abnormalities have been shown to correlate better than others with the progression of the disease. The aim of the study was to evaluate the prevalence of the most frequent renal US abnormalities in dogs at different stages of CKD, and to investigate their association with CKD International Renal Interest Society (IRIS) stages. Medical records and ultrasonographical report of 855 dogs were retrospectively included. The most frequent renal ultrasonographic abnormalities were: increased cortical echogenicity, abnorma
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Gardiner, Jessica. "Iris Winston. Staging a Legend: A History of Ottawa Little Theatre." Theatre Research in Canada 20, no. 2 (1999): 259–62. http://dx.doi.org/10.3138/tric.20.2.259.

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4

Roberts, Philipp K., Debra A. Goldstein, and Amani A. Fawzi. "Anterior Segment Optical Coherence Tomography Angiography for Identification of Iris Vasculature and Staging of Iris Neovascularization: A Pilot Study." Current Eye Research 42, no. 8 (2017): 1136–42. http://dx.doi.org/10.1080/02713683.2017.1293113.

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5

Groves, Ellie. "Dietary management of the cat with early chronic kidney disease." Companion Animal 25, no. 6 (2020): 168–74. http://dx.doi.org/10.12968/coan.2020.0013b.

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Chronic kidney disease (CKD) is a highly prevalent disease and common cause of morbidity and mortality in older cats. Early diagnosis and management of CKD is thought to be able to slow disease progression and impact positively on quality of life and longevity. Dietary management with a therapeutic renal diet is regarded as the mainstay of treatment for feline CKD from International Renal Interest Society (IRIS) stage 2 onwards. However, since the advent of markers such as symmetric dimethylarginine that have enabled clinicians to detect non-azotaemic CKD (IRIS stage 1 and some early stage 2 p
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Pierantozzi, Marco, Xavier Roura, Saverio Paltrinieri, Marco Poggi, and Andrea Zatelli. "Variation of Proteinuria in Dogs with Leishmaniasis Treated with Meglumine Antimoniate and Allopurinol: A Retrospective Study." Journal of the American Animal Hospital Association 49, no. 4 (2013): 231–36. http://dx.doi.org/10.5326/jaaha-ms-5840.

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A retrospective study was performed using 53 client owned dogs with leishmaniasis to determine whether the degree of proteinuria, evaluated by the urine protein/creatinine ratio (UP/C), changes following treatment with meglumine antimoniate and allopurinol. Medical records of dogs with leishmaniasis in clinical stage C (according to the Canine Leishmaniasis Working Group staging system) and either proteinuric or borderline proteinuric (according to the International Renal Interest Society [IRIS] staging system) were reviewed. All dogs were treated with meglumine antimoniate and allopurinol for
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IWAMA, Ryosuke, Tsubasa SATO, Masaaki KATAYAMA, et al. "Relationship of glomerular filtration rate based on serum iodixanol clearance to IRIS staging in cats with chronic kidney disease." Journal of Veterinary Medical Science 77, no. 8 (2015): 1033–35. http://dx.doi.org/10.1292/jvms.14-0494.

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8

Taunton, Matthew. "Chorus and Agon in the Political Novel: Staging Left-Wing Arguments in H. G. Wells, Iris Murdoch, and Doris Lessing." MFS Modern Fiction Studies 67, no. 2 (2021): 247–71. http://dx.doi.org/10.1353/mfs.2021.0011.

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9

Moraes, Reiner Silveira de, Antônio Carlos Severino Neto, Gabriel Lopes Germano, Henrique Trevizoli Ferraz, and Alana Flávia Romani. "Chronic kidney disease in a dog of the Teckel breed: case report." Acta Veterinaria Brasilica 14, no. 4 (2020): 215–19. http://dx.doi.org/10.21708/avb.2020.14.4.9322.

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Chronic kidney disease (CKD) is a disease characterized by the gradual and functional loss of renal mass, affecting its physiology leading to clinical manifestations. The CKD reaches dogs of several breeds causing important clinical alterations. Some laboratory tests are determinant for the correct diagnosis and thus for the implementation of the most appropriate treatment. The urinalysis, urinary protein-creatinine ratio (UPC) evaluation, urea, and creatinine dosage together with the symmetric dimethylarginine dosage (SDMA), urinary tract ultrasonography and blood pressure monitoring, are the
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10

Scardoel, Bruna, Simone G. R. Gomes, Cinthia Ribas Martorelli, and Rafael Garabet Agopian. "Chronic kidney disease in dogs and cats – retrospective study and literature review." Clínica Veterinária XXV, no. 145 (2020): 64–78. http://dx.doi.org/10.46958/rcv.2020.xxv.n.145.p.64-78.

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Chronic kidney disease (CKD) is defined as the structural and/or functional impairment of one or both kidneys of 3 or more months duration, and resulting in irreversible loss of renal functions. The International Renal Interest Society (IRIS) classifies CKD into 4 stages according to levels of serum creatinine and symmetric dimethylarginine (SDMA), Urinary protein/creatinine ratio and systemic arterial pressure are subcriteria used in stating the disease. We reviewed the records of 50 dogs and 67 cats diagnosed with CKD. The staging criteria was recorded in 39.5% of the dogs (n = 32), and 60.5
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11

Deininger, Michael W. "Milestones and Monitoring in Patients with CML Treated with Imatinib." Hematology 2008, no. 1 (2008): 419–26. http://dx.doi.org/10.1182/asheducation-2008.1.419.

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AbstractImatinib is the therapeutic standard for newly diagnosed patients with chronic myeloid leukemia (CML). Recent updates of the IRIS trial, a study of standard-dose imatinib in newly diagnosed chronic-phase patients treated with 400 mg imatinib daily, suggest a stabilization of progression-free survival curves at a high level, implying that the majority of patients will do well on standard therapy. However, some 20% to 30% of patients will fail on imatinib and require alternative therapies. Identification of those patients likely to fail would be desirable to allow for more intensive ther
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12

Martínez, Pedro P., and Marileda B. Carvalho. "Participação da excreção renal de cálcio, fósforo, sódio e potássio na homeostase em cães sadios e cães com doença renal crônica." Pesquisa Veterinária Brasileira 30, no. 10 (2010): 868–76. http://dx.doi.org/10.1590/s0100-736x2010001000010.

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Na doença renal crônica (DRC) a manutenção da homeostase de água e sódio é o primeiro problema a ser contornado pelo organismo e com o agravamento das lesões renais surgem outros problemas graves relacionados à homeostase de cálcio e fósforo. O presente estudo tem por escopo avaliar a excreção renal de cálcio, fósforo, sódio e potássio, e o perfil sérico destes eletrólitos em cães normais e em cães com DRC naturalmente adquirida. Foram avaliados três grupos de cães adultos, machos ou fêmeas, de raças variadas. Animais normais compuseram o grupo controle (G1) e os cães com DRC foram distribuído
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Paltrinieri, Saverio, Marco Giraldi, Amanda Prolo, et al. "Serum symmetric dimethylarginine and creatinine in Birman cats compared with cats of other breeds." Journal of Feline Medicine and Surgery 20, no. 10 (2017): 905–12. http://dx.doi.org/10.1177/1098612x17734066.

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Objectives The aim of this study was to assess whether, in contrast to serum creatinine, which is higher in Birman cats than in other breeds, the serum concentration of symmetric dimethylarginine (SDMA) is comparable in clinically healthy Birmans and in the general feline population. This could allow, in this breed, to better evaluate chronic kidney disease (CKD). Methods Serum creatinine and SDMA were measured in clinically healthy Birmans (n = 50) and in cats of other breeds (n = 46), and the results were statistically compared. A breed-specific reference interval (RI) was established for Bi
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O'Gorman, Siobhan. "Opening Matierals." Review of Irish Studies in Europe 4, no. 1 (2021): i—iii. http://dx.doi.org/10.32803/rise.v4i1.2700.

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15

Boltwood, Scott. "“THE INEFFACEABLE CURSE OF CAIN”: RACE, MISCEGENATION, AND THE VICTORIAN STAGING OF IRISHNESS." Victorian Literature and Culture 29, no. 2 (2001): 383–96. http://dx.doi.org/10.1017/s1060150301002078.

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THROUGHOUT THE NINETEENTH CENTURY both the English popular and scientific communities increasingly argued for a distinct racial difference between the Irish Celt and the English Saxon, which conceptually undermined the Victorian attempt to form a single kingdom from the two peoples. The ethnological discourse concerning Irish identity was dominated by English theorists who reflect their empire’s ideological necessity; thus, the Celt and Saxon were often described as racial siblings early in the nineteenth century when union seemed possible, while later descriptions of the Irish as members of a
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16

Ransmayr, Christoph. "The Stage by the Sea." Scenario: A Journal of Performative Teaching, Learning, Research I, no. 2 (2007): 1–6. http://dx.doi.org/10.33178/scenario.1.2.1.

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Contemporary Austrian author ChristophRansmayr takes us to a place on the South Irish coast where, amidst beautiful nature, there is music and dance under the open skies, and staging is accomplished with the simplest means. There, active participation in performing arts is experienced as a natural and integral component of everyday existence; it lightens personal loads and supports the coastal inhabitants’ courage to face life.
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Gaviña-Costero, María. "Brian Friel in Spain: An Off-Centre Love Story." Estudios Irlandeses, no. 16 (March 17, 2021): 110–24. http://dx.doi.org/10.24162/ei2021-10074.

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Spanish theatres are not prolific in the staging of Irish playwrights. However, the Northern Irish writer Brian Friel (1929-2015) has been a curious exception, his plays having been performed in different cities in Spain since William Layton produced Amantes: vencedores y vencidos (Lovers: Winners and Losers) in 1972. The origin of Friel’s popularity in this country may be attributed to what many theatre directors and audiences considered to be a parallel political situation between post-colonial Ireland and the historical peripheral communities with a language other than Spanish: Catalonia, t
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18

Pratt, Paula. "Dancing with Myriam: Creating and Staging a New Metaphor for the Process of Translation." TranscUlturAl: A Journal of Translation and Cultural Studies 7, no. 1 (2015): 71. http://dx.doi.org/10.21992/t9q62m.

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This article tells the story, and analyzes the development, of a “staged metaphor” for the translation process, from its chance inception over ten years ago, to the more recent revision and staging of the script. In 2005, I was teaching world literature at Al Akhawayn University in Ifrane, Morocco, while also researching the writing of Irish and North African women. I chose to focus on those women writing in Irish, Tachelhit, Arabic, or French, whose work had been translated into English. I was initially inspired by Nuala Ni Dhomhnaill’s poem, “The Language Issue,” which compares the "sending
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19

HILL, SHONAGH. "The Crossing of Boundaries: Transgression Enacted." Theatre Research International 36, no. 3 (2011): 278–82. http://dx.doi.org/10.1017/s0307883311000526.

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Feminist discourse has proven to be a vital component in the expanding field of Irish theatre studies owing to its exposure of elided work and the articulation of unrepresented voices. Irish women's participation in the public sphere and cultural fabric of society has been hindered in the course of the twentieth century and this is reflected in limiting representations of femininity as perpetuated by discourses of nationalism and Catholicism: the dominant imagery of the idealized mother which merges the feminized nation – Mother Ireland – and the Virgin Mary. In Hegemony and Fantasy in Irish D
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20

Sacchetti, Clara, and Batia Stolar. "Dancing Italian Culture: Venezia et al." Congress on Research in Dance Conference Proceedings 2016 (2016): 337–43. http://dx.doi.org/10.1017/cor.2016.45.

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How does Le Stelle, an ethnic dance group in the multicultural city of Thunder Bay, Ontario, Canada, represent Italian culture? Our article broaches this question by analyzing Le Stelle's 2012 “Carnivale of Venezia” dance. While the number is meant to evoke the Italian Renaissance, it creatively uses kinetic movements from ballet, Irish step dancing, and the Italian tarantella. It is staged to a 1950s Mantovani song mixed with music from Assassin's Creed II; and it utilizes Italian peasant costuming and Venetian masks. Our paper examines Le Stelle's use of these hybridities in staging Italian
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McMullan, Anna, and Trish McTighe. "Samuel Beckett and Irish Scenography." Irish University Review 45, no. 1 (2015): 141–56. http://dx.doi.org/10.3366/iur.2015.0157.

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This essay offers some glimpses of the parallel histories of Beckett and Irish scenography, and explores how they have impacted on each other. In particular, we investigate the intersections between Beckett and theatre in Dublin in the 1920s and 1930s, considering whether the staging innovations of the Dublin theatres of Beckett's formative years helped to shape his scenographic imagination. We then focus on Louis le Brocquy's designs for the Gate Theatre production of Waiting for Godot in 1988, which went on to constitute the core of their Beckett Festival, launched in 1991, with various revi
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Russell, Richard Rankin. "Deprovincializing Brian Friel's Drama in America, 2009 and 2014: Dancing at Lughnasa in Fort Myers, Florida, and Faith Healer in Houston, Texas." Irish University Review 45, no. 1 (2015): 103–16. http://dx.doi.org/10.3366/iur.2015.0154.

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While American regional theatre has flourished for decades, hardly any critics with a national profile pay attention to it, but theatre critic Terry Teachout has recently argued that criticism must catch up with this ‘deprovincialized’ drama, drawing upon his viewing of Brian Friel's Dancing at Lughnasa in a memorable 2009 production by the Florida Repertory Theatre in Fort Myers. I tentatively explore through that production of Lughnasa what implications its staging in a locale with a strong Hispanic concentration might have for American theatre and for its growing immigrant population as the
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Imamura, Toshihiro, and Allan I. Pack. "48019 Create a mouse model of chronic sleep deprivation by specific-neuron targeted ablation." Journal of Clinical and Translational Science 5, s1 (2021): 14. http://dx.doi.org/10.1017/cts.2021.439.

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ABSTRACT IMPACT: A mouse model of minimally-invasive chronic sleep deprivation is essential for elucidating the impact of sleep deprivation on various health issues, and it would lead to the possibility of sleep as a therapeutic target. OBJECTIVES/GOALS: The lack of sleep has been associated with various health conditions. In mice, sleep deprivation has been achieved mainly by physical disturbances, which raises concern about confounding effects by stresses. Without physical disturbance, targeted neuron ablation can address this methodological flaw. METHODS/STUDY POPULATION: AdultVgat-IRES-cre
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Haughton, Miriam. "Irish Theatre in the 21st Century." Cadernos de Letras da UFF 31, no. 60 (2020): 45–64. http://dx.doi.org/10.22409/cadletrasuff.2020n60a772.

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My research examines the staging contexts of these case studies, locating them among the traumatic histories they were drawn from, which centre on women saying, sometimes loudly, and sometimes quietly, #MeToo. However, they said this traditionally in isolated historical contexts, dominated by the overwhelming power of the Irish institutions of church, family, and nation, and without the immediate collective community that one can access online today. For the women depicted in these productions, there was little opportunity to challenge the normalised patterns of abuse they were subjected to as
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Crotty, Rory, Maeve P. Crowley, Mary R. Cahill, and Brian R. Healey Bird. "Irish Hospitals Meet Proposed International Guidelines For Non-Hodgkin Lymphoma Management, But Areas For Improvement Remain." Blood 122, no. 21 (2013): 5591. http://dx.doi.org/10.1182/blood.v122.21.5591.5591.

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Abstract Introduction High-grade non-Hodgkin lymphoma is an aggressive condition that requires equally aggressive management. Due to the possibility of curative treatment if the disease is effectively managed, rapid diagnosis, precise staging, and swift commencement of treatment are crucial. In Ireland there is little reliable data on how closely guidelines in non-Hodgkin lymphoma treatment are followed. In order to obtain better data, we replicated a recent study carried out in the Netherlands by Wennekes and colleagues (J Clin Oncol 2011 April 10;29(11): 1436-1444). Methods This study was ca
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Schmitt-Kilb, Christian. "The End(s) of Language in Brian Friel’s Translations and Enda Walsh’s Disco Pigs and misterman." Scenario: A Journal of Performative Teaching, Learning, Research III, no. 2 (2009): 61–70. http://dx.doi.org/10.33178/scenario.3.2.5.

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In my analysis of Brian Friel's modern classic drama Translations (1980) and Enda Walsh's plays Disco Pigs (1996) and misterman (2001), I have chosen not to consider these in order to point towards structural or plot parallels between the plays, nor to emphasise the interdependency of the two authors; I am instead concerned with their differences, particularly with differences in their approach to language as a medium of (often failed) communication. I would like to suggest that it is possible to read the plays as signs of their times within an Irish context. At the time of its first staging i
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FitzPatrick Dean, Joan. "Hilton Edwards, Brecht and the Brechtian." Review of Irish Studies in Europe 4, no. 1 (2021): 82–98. http://dx.doi.org/10.32803/rise.v4i1.2622.

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The Dublin Gate Theatre Company’s repertory of international, often experimental plays offers perhaps the clearest distinction between the Gate and the Abbey in the mid-twentieth century. A growing body of scholarship focuses on how Hilton Edwards and Micheál mac Liammóir deployed innovative, non-realistic staging techniques and brought to Ireland design elements associated with European artists. The Gate’s international remit can also be seen in its production of plays not merely authored by foreign playwrights, but focused on issues outside the conventional purview of Irish politics, includi
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Tait, Peta. "Contemporary Politics and Empathetic Emotions: Company B's Antigone." New Theatre Quarterly 26, no. 4 (2010): 351–60. http://dx.doi.org/10.1017/s0266464x10000655.

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Sydney-based Company B's 2008 season included The Burial at Thebes: Sophocles's Antigone in Irish poet Seamus Heaney's translation. This article shows how the production conveyed notions of war, social upheaval, displacement, and exile that are relevant to contemporary Australian spectators. With its ethnic and racial diversity, and one overt reference to the plight of indigenous people under colonial rule and its legacy, the production confirmed that the emotional resonances in this staging of Antigone reflect and yet transcend the contemporary Australian situation; and Peta Tait here argues
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Connell, Louise Catherine, Charlotte Stuart, Norma Daly, Brian Mehigan, and M. John Kennedy. "Locally advanced rectal cancer: The value of magnetic resonance imaging as a predictive tool." Journal of Clinical Oncology 31, no. 15_suppl (2013): e14666-e14666. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e14666.

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e14666 Background: Magnetic Resonance Imaging (MRI) of pelvis stratifies patients (pts) with rectal cancer (ca) according to locally advanced disease (dx) & risk of local recurrence. By determining the extent of lymph node (LN) positivity, it enables the appropriate selection of pts for neoadjuvant therapy (NAT) prior to curative surgical resection (Sx). We assessed our institution’s experience of NAT versus upfront Sx in stage I-III rectal ca to ascertain the utility of MRI as a predictive tool in LN status evaluation. Methods: We retrospectively reviewed a prospectively maintained databa
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Heinz, Sarah. "Unsettling Australia: Disturbing White Settler Homemaking in Peter Carey’s True History of the Kelly Gang." Humanities 9, no. 4 (2020): 115. http://dx.doi.org/10.3390/h9040115.

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Proceeding from Australia’s specific situation as a settler colony, this article discusses how the ambivalences and fissures of settler subjectivity shape processes of homemaking. Settler homemaking depends on the disturbance of Indigenous Australians’ homelands via dispossession, exclusion, and genocide, but it equally depends upon the creation of a white settler subject as innocent, entitled, and belonging to what has been called ‘white indigeneity’. The article traces this double disturbance in Peter Carey’s novel True History of the Kelly Gang (2000). Carey’s rewriting of the iconic Kelly
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da Silva Santana, Cesar Augusto, Colm Lordan, and Anne Marie Power. "Theoretical size at the onset of maturity and its density-dependent variability as an option in crustacean fisheries management." ICES Journal of Marine Science 78, no. 4 (2021): 1421–33. http://dx.doi.org/10.1093/icesjms/fsab040.

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Abstract Theoretical size at the onset of maturity (TSOM) for female Norway lobster was estimated by a new methodology based on the probability distributions of mature individuals built on physiological maturity measures. Onset of maturity using TSOM varied from 18.4- to 33.7-mm carapace length for the Irish functional management units (FUs). These estimates showed a significant negative linear relationship (R2 = 0.60) with population density and a significant positive linear relationship with average size in females (R2 = 0.84). The size class at which 50% of the females are sexually mature (
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Barry, M., and M. R. Kell. "Profile of axillary nodal disease from the Irish National Breast Cancer Screening Program in the era of sentinel node biopsy." Journal of Clinical Oncology 27, no. 15_suppl (2009): e11629-e11629. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e11629.

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e11629 Introduction: Ireland offers a socialized national breast cancer screening program (Breastcheck) to women between 50 and 65 years of age with the aim of reducing breast cancer mortality. Historical axillary staging for screen detected breast cancer has shown nodal positivity in 25% of cases. This study examines axillary nodal disease from the Irish national breast cancer screening program in the era of sentinel lymph node biopsy (SLNB). Methods: Patients with clinically and radiologically early stage screen detected breast cancer and negative axillae are offered therapeutic surgery with
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Bambury, Richard Martin, Claire Brady, Aoife McCarthy, Stewart Fleming, Nicholas J. Mayer, and Derek Gerard Power. "Translocation renal cell carcinomas: An evolving entity." Journal of Clinical Oncology 30, no. 5_suppl (2012): 472. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.472.

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472 Background: Translocation renal cell carcinomas (RCCs) are a novel, rare and distinct clinicopathological entity. The term refers to RCCs with overexpression of transcription factor E3 (TFE3) due to translocation involving the Xp11 locus or less commonly with overexpression of transcription factor EB (TFEB) due to a t(6:11) translocation. In children it is estimated that these tumours account for 40% of RCCs but in adults this proportion is estimated to be 1-4%. As these neoplasms are only recently recognised, outcome data are premature. We report 2 cases of translocation RCC in an Irish r
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Balleyguier, Corinne, Ariane Dunant, Luc Ceugnart, et al. "Preoperative Breast Magnetic Resonance Imaging in Women With Local Ductal Carcinoma in Situ to Optimize Surgical Outcomes: Results From the Randomized Phase III Trial IRCIS." Journal of Clinical Oncology 37, no. 11 (2019): 885–92. http://dx.doi.org/10.1200/jco.18.00595.

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PURPOSE We evaluated the addition of breast magnetic resonance imaging (MRI) to standard radiologic evaluation on the re-intervention rate in women with ductal carcinoma in situ (DCIS) undergoing breast-conserving surgery. PATIENTS AND METHODS Women with biopsy-proven DCIS corresponding to a unifocal microcalcification cluster or a mass less than 30 mm were randomly assigned to undergo MRI or standard evaluation. The primary end point was the re-intervention rate for positive or close margins (< 2 mm) in the 6 months after randomization ( ClinicalTrials.gov identifier: NCT01112254). RESULTS
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Doherty, Mark, Darren Cowzer, Ciara Marie Kelly, Jodie Emma Battley, Gregory D. Leonard, and Derek Gerard Power. "Combination therapy with radiation and weekly paclitaxel/carboplatin as definitive treatment for locally advanced esophageal cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): e15196-e15196. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15196.

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e15196 Background: Definitive chemoradiotherapy (CRT) is an established treatment option in localised esophageal cancer. While most patients are treated with cisplatin and fluorouracil, alternative chemotherapy regimens have been used. The combination of carboplatin and paclitaxel (CP) has been validated in a neoadjuvant CRT trial by the CROSS study. There has also been a phase II study (v. Meerten, ASCO 2010, e14508) showing efficacy and tolerability of this regimen in the definitive setting with radiation doses of 50.4Gy/28#. We report our experience using this strategy in two Irish centres.
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Doherty, Mark, Darren Cowzer, Ciara Marie Kelly, Jodie Emma Battley, Gregory Leonard, and Derek Gerard Power. "Combination therapy with radiation and weekly paclitaxel/carboplatin as definitive treatment for locally advanced esophageal cancer." Journal of Clinical Oncology 31, no. 4_suppl (2013): 133. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.133.

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133 Background: Definitive chemoradiotherapy (CRT) is an established treatment option in localised esophageal cancer. While most patients are treated with cisplatin and fluorouracil, alternative chemotherapy regimens have been used. The combination of carboplatin and paclitaxel (CP) has been validated in a neoadjuvant CRT trial by the CROSS study. There has also been a phase II study (v. Meerten, ASCO 2010, e14508) showing efficacy and tolerability of this regimen in the definitive setting with radiation doses of 50.4Gy/28#. We report our experience using this strategy in two Irish centres. Me
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Power, Derek Gerard, Jodie E. Battley, Aoife McCarthy, et al. "Translocation renal cell carcinomas: An evolving entity." Journal of Clinical Oncology 30, no. 15_suppl (2012): e15078-e15078. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e15078.

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e15078 Background: Translocation renal cell carcinomas (tRCCs) are a novel, rare and distinct clinicopathological entity. The term refers to RCCs with overexpression of transcription factor E3 (TFE3) due to translocation involving the Xp11 locus or less commonly with overexpression of transcription factor EB (TFEB) due to a t(6:11) translocation. In children it is estimated that these tumours account for 40% of RCCs but in adults this proportion is estimated to be 1-4%. These neoplasms are only recently recognised and outcome data are premature. We report 2 cases of tRCC in an Irish regional c
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Gardiner, Jessica. "Iris Winston. Staging a Legend: A History of Ottawa Little Theatre." Theatre Research in Canada 20, no. 2 (2019). http://dx.doi.org/10.7202/1062389ar.

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39

Lucena, Evandro, Daniel Cohen Goldemberg, Luiz Claudio Santos Thuler, and Andreia Cristina de Melo. "Epidemiology of uveal melanoma in Brazil." International Journal of Retina and Vitreous 6, no. 1 (2020). http://dx.doi.org/10.1186/s40942-020-00261-w.

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Abstract Purpose To report the prevalence of uveal melanoma in a Hospital database in Brazil over the period of 16 years (2000 to 2016). Design Descriptive epidemiological study evaluating the Brazilian Hospital Based Cancer Registries. Participants/methods Uveal melanomas were identified based on ICD-O-3 codes C69.3 [choroid], C69.4 [ciliary body and iris], and C69.2 [retina]) derived from the Integrator Registry database. Kolmogorov–Smirnov Test was used for evaluation of normality of data, t-test and Chi square were used for categorical and continuous variables respectively using SPSS Softw
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Sivasakthi, R., T. Satheesh Kumar, K. Padmanath, M. Chandrasekar, P. Sriram, and V. Pandiyan. "Urinary cystatin C as biomarker for identification of kidney disease in dogs." Indian Journal of Animal Research, no. 00 (April 26, 2018). http://dx.doi.org/10.18805/ijar.b-3481.

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The aim of the study was to identify urinary biomarker for early detection of renal dysfunction in dogs. Paired blood and urine samples were analysed from dogs classified on the basis of International Renal Interest Society (IRIS) staging system. Serum biochemistry revealed a highly significant increase in blood urea nitrogen and creatinine levels in dogs with kidney disease. Urinalysis also revealed a highly significant increase in the level of urinary protein and urinary protein creatinine (UPC) ratio in dogs with kidney disease. A highly significant decrease in urinary creatinine and specif
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Antunes Ribeiro, José Francisco, Tácia Tavares Aquinas Liguori, André Nanny Vieira Le Sueur, et al. "A Transversal Study of Biochemical Profile, Urinalysis, UPC, Electrolytes and Blood Pressure in Dogs with Chronic Kidney Disease." Acta Scientiae Veterinariae 48 (May 16, 2020). http://dx.doi.org/10.22456/1679-9216.102937.

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Background: Chronic kidney disease (CKD) affects both dogs and cats, mainly elderly animals, due to tubulointerstitial inflammation associated with the increase of fibrosis through the excess deposition of extracellular matrix (ECM) which leads to decrease glomerular filtration. Many different underlying renal diseases can affect the kidneys of dogs such as congenital or acquired in origin. Therefore, the main objective of this transversal study was to evaluate the epidemiology through clinical and laboratory evaluation of 225 client-owned dogs with CKD.Materials, Methods & Results: Comple
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Schaefer, Gabriela Da Cruz, Silvana Bellini Vidor, Juliana Toloi Jeremias, Cristiana Fonseca Ferreira Pontieri, Marcio Antonio Brunetto, and Fernanda Vieira Amorim Da Costa. "Clinical and Nutritional Follow-up of Cats with Chronic Kidney Disease Fed with a Renal Prescription Diet." Acta Scientiae Veterinariae 49 (April 14, 2021). http://dx.doi.org/10.22456/1679-9216.106220.

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Background: The use of prescription diets for cats with chronic kidney disease (CKD) is one of the main management approach of this disease in cats, and is considered a renoprotective strategy that may promote increased survival and/or improve quality of life, according to the stage of CKD. Besides that, nutritional assessment is important to monitor the maintenance of quality of life of the patients and their response to disease, especially those with chronic conditions. The aim of this study was to follow the clinical and nutritional status of cats with chronic kidney disease (CKD) IRIS stag
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Garg, Gaurav, Paul T. Finger, Tero T. Kivelä, et al. "Patients presenting with metastases: stage IV uveal melanoma, an international study." British Journal of Ophthalmology, January 15, 2021, bjophthalmol—2020–317949. http://dx.doi.org/10.1136/bjophthalmol-2020-317949.

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ObjectiveTo analyse ocular and systemic findings of patients presenting with systemic metastasis.Methods and analysisIt is an international, multicentre, internet-enabled, registry-based retrospective data analysis. Patients were diagnosed between 2001 and 2011. Data included: primary tumour dimensions, extrascleral extension, ciliary body involvement, American Joint Committee on Cancer (AJCC)-tumour, node, metastasis staging, characteristics of metastases.ResultsOf 3610 patients with uveal melanoma, 69 (1.9%; 95% CI 1.5 to 2.4) presented with clinical metastasis (stage IV). These melanomas or
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"Development of Canine Chronic Kidney Disease Model: A Pilot Study." International Journal of Veterinary Science 10, no. 4 (2021): 286–93. http://dx.doi.org/10.47278/journal.ijvs/2021.056.

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Chronic kidney disease (CKD) is a worldwide health problem with a poor prognosis. The exploration of possible medical intervention requires the presence of a suitable animal model. This work aims to induce a model of canine CKD with persistent uremia. Three dogs were used to develop canine CKD models with different techniques based on the remnant kidney model. Model (1) was subjected to excision of one renal pole of the right kidney. Model (2) was subjected to the excision of two renal poles of the right kidney. Model (3) underwent ligation of two renal arterial branches of the right kidney. A
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O’Connor, Maureen. "Alice’s Garden: Imagining Agency in the Natural World in Clare Boylan’s Black Baby." Estudios Irlandeses, October 31, 2020, 42–52. http://dx.doi.org/10.24162/ei2020-9752.

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The Irish writer Clare Boylan is something of a forgotten figure, despite enjoying significant literary success in her lifetime. Because of her untimely death, little critical work has been done on her fiction. Her blackly comic sensibility responds sensitively to characters situated in culturally specific environments, with particular attention paid to the vexed and contradictory position of women in their relationship to the natural world, and so this essay conducts a reading of her 1988 novel, Black Baby, using the insights of feminist new materialism and critical posthumanism, especially a
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Chai, Mengyu, Xiuchun Li, Yaxin Zhang, et al. "A Nomogram Integrating Ferroptosis- and Immune-Related Biomarkers for Prediction of Overall Survival in Lung Adenocarcinoma." Frontiers in Genetics 12 (September 1, 2021). http://dx.doi.org/10.3389/fgene.2021.706814.

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Ferroptosis plays a dual role in cancer, which is known to be affected to antitumor immune responses. However, the association between ferroptosis and antitumor immune responses is uncertain in lung adenocarcinoma (LUAD). In this work, 38 ferroptosis-related genes (FRGs) and 429 immune-related genes (IRGs) were identified as being differentially expressed between tumor and normal samples. Two risk score formulas consisting of seven FRGs and four IRGs, respectively, were developed by Lasso-penalized Cox regression and verified in the GSE13213 dataset. The CIBERSORT algorithm was used to estimat
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Zhao, Kaifei, Lin Xu, Feng Li, et al. "Identification of hepatocellular carcinoma prognostic markers based on 10-immune gene signature." Bioscience Reports 40, no. 8 (2020). http://dx.doi.org/10.1042/bsr20200894.

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Abstract Background: Due to the heterogeneity of hepatocellular carcinoma (HCC), hepatocelluarin-associated differentially expressed genes were analyzed by bioinformatics methods to screen the molecular markers for HCC prognosis and potential molecular targets for immunotherapy. Methods: RNA-seq data and clinical follow-up data of HCC were downloaded from The Cancer Genome Atlas (TCGA) database. Multivariate Cox analysis and Lasso regression were used to identify robust immunity-related genes. Finally, a risk prognosis model of immune gene pairs was established and verified by clinical feature
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Luiten, Jacky D., Ernest J. T. Luiten, Maurice J. C. van der Sangen, et al. "Patterns of treatment and outcome of ductal carcinoma in situ in the Netherlands." Breast Cancer Research and Treatment, January 1, 2021. http://dx.doi.org/10.1007/s10549-020-06055-w.

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Abstract Purpose To spare DCIS patients from overtreatment, treatment de-escalated over the years. This study evaluates the influence of these developments on the patterns of care in the treatment of DCIS with particular interest in the use of breast conserving surgery (BCS), radiotherapy following BCS and the use and type of axillary staging. Methods In this large population-based cohort study all women, aged 50–74 years diagnosed with DCIS from January 1989 until January 2019, were analyzed per two-year cohort. Results A total of 30,417 women were diagnosed with DCIS. The proportion of patie
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Yan, Qian, Wenjiang Zheng, Boqing Wang, et al. "A prognostic model based on seven immune-related genes predicts the overall survival of patients with hepatocellular carcinoma." BioData Mining 14, no. 1 (2021). http://dx.doi.org/10.1186/s13040-021-00261-y.

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Abstract Background Hepatocellular carcinoma (HCC) is a disease with a high incidence and a poor prognosis. Growing amounts of evidence have shown that the immune system plays a critical role in the biological processes of HCC such as progression, recurrence, and metastasis, and some have discussed using it as a weapon against a variety of cancers. However, the impact of immune-related genes (IRGs) on the prognosis of HCC remains unclear. Methods Based on The Cancer Gene Atlas (TCGA) and Immunology Database and Analysis Portal (ImmPort) datasets, we integrated the ribonucleic acid (RNA) sequen
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Mahon, Elaine. "Ireland on a Plate: Curating the 2011 State Banquet for Queen Elizabeth II." M/C Journal 18, no. 4 (2015). http://dx.doi.org/10.5204/mcj.1011.

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IntroductionFirmly located within the discourse of visible culture as the lofty preserve of art exhibitions and museum artefacts, the noun “curate” has gradually transformed into the verb “to curate”. Williams writes that “curate” has become a fashionable code word among the aesthetically minded to describe a creative activity. Designers no longer simply sell clothes; they “curate” merchandise. Chefs no longer only make food; they also “curate” meals. Chosen for their keen eye for a particular style or a precise shade, it is their knowledge of their craft, their reputation, and their sheer abi
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