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Journal articles on the topic 'IRMmp'

Author: Grafiati

Published: 14 September 2024

Last updated: 31 July 2025

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1

Roumeguere, T., A. Noël, F. Aoun, et al. "Apport des biopsies ciblées par fusion d’image (us/irmmp) en complément à des biopsies systématisées chez des patients maintenant une suspicion de cancer prostatique après une ou plusieurs séries de biopsies systématisées négatives." Progrès en Urologie 26, no. 13 (2016): 811–12. http://dx.doi.org/10.1016/j.purol.2016.07.281.

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Richter, S., A. Alonso, W. De Bolle, et al. "Re-certification of a series of uranium isotope reference materials: IRMM-183, IRMM-184, IRMM-185, IRMM-186 and IRMM-187." International Journal of Mass Spectrometry 247, no. 1-3 (2005): 37–39. http://dx.doi.org/10.1016/j.ijms.2005.07.008.

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Mossialos, Dimitris, Jean-Marie Meyer, Herbert Budzikiewicz, et al. "Quinolobactin, a New Siderophore ofPseudomonas fluorescens ATCC 17400, the Production of Which Is Repressed by the Cognate Pyoverdine." Applied and Environmental Microbiology 66, no. 2 (2000): 487–92. http://dx.doi.org/10.1128/aem.66.2.487-492.2000.

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ABSTRACT Transposon mutant strain 3G6 of Pseudomonas fluorescensATCC 17400 which was deficient in pyoverdine production, was found to produce another iron-chelating molecule; this molecule was identified as 8-hydroxy-4-methoxy-quinaldic acid (designated quinolobactin). The pyoverdine-deficient mutant produced a supplementary 75-kDa iron-repressed outer membrane protein (IROMP) in addition to the 85-kDa IROMP present in the wild type. The mutant was also characterized by substantially increased uptake of 59Fe-quinolobactin. The 75-kDa IROMP was produced by the wild type after induction by quino

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Lapitajs, G., F. Hendrickx, A. Verbruggen, and A. Lamberty. "An IRMM 87Rb isotopic reference material IRMM-618." International Journal of Mass Spectrometry and Ion Processes 152, no. 1 (1996): 69–77. http://dx.doi.org/10.1016/0168-1176(95)04328-4.

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Chibber, Sanjay, and Sonia B. Bhardwaj. "Protection in a mouse peritonitis model mediated by iron-regulated outer-membrane protein of Salmonella typhi coupled to its Vi antigen." Journal of Medical Microbiology 53, no. 7 (2004): 705–9. http://dx.doi.org/10.1099/jmm.0.05378-0.

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Vi polysaccharide and iron-regulated outer-membrane proteins (IROMPs) were extracted and purified from the standard strain of Salmonella typhi, Ty2. These were then conjugated by chemical coupling using the carbodimide method. Vi–IROMP conjugate was tested for its ability to protect against colonization by S. typhi in different organs. Mice immunized with 2.5 μg Vi–IROMP conjugate showed the most protection, as the least bacterial colonization of spleen, liver and Peyer's patches was observed. Peritoneal macrophages obtained from conjugate-treated mice phagocytosed bacteria efficiently. Circul

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Duta, Steluta, Michael Berglund, and Philip Taylor. "Updated certified values of the lithium isotopic reference materials IRMM-016, IRMM-015 and IRMM-615." Rapid Communications in Mass Spectrometry 23, no. 6 (2009): 937–38. http://dx.doi.org/10.1002/rcm.3930.

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Cocchieri, Riccardo, Bertus van de Wetering, Sjoerd van Tuijl, Iman Mousavi, Robert Riezebos, and Bastian de Mol. "At the Crossroads of Minimally Invasive Mitral Valve Surgery—Benching Single Hospital Experience to a National Registry: A Plea for Risk Management Technology." Journal of Cardiovascular Development and Disease 9, no. 8 (2022): 261. http://dx.doi.org/10.3390/jcdd9080261.

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Almost 30 years after the first endoscopic mitral valve repair, Minimally Invasive Mitral Valve Surgery (MIMVS) has become the standard at many institutions due to optimal clinical results and fast recovery. The question that arises is can already good results be further improved by an Institutional Risk Management Performance (IRMP) system in decreasing risks in minimally invasive mitral valve surgery (MIMVS)? As of yet, there are no reports on IRMP and learning systems in the literature. (2) Methods: We described and appraised our five-year single institutional experience with MIMVS in isola

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Reggiani, Henrique, Kevin C. Schlaufman, and Andrew R. Casey. "Iron-rich Metal-poor Stars and the Astrophysics of Thermonuclear Events Observationally Classified as Type Ia Supernovae. I. Establishing the Connection." Astronomical Journal 166, no. 3 (2023): 128. http://dx.doi.org/10.3847/1538-3881/ace68c.

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Abstract The progenitor systems and explosion mechanisms responsible for the thermonuclear events observationally classified as Type Ia supernovae are uncertain and difficult to uniquely constrain using traditional observations of Type Ia supernova host galaxies, progenitors, light curves, and remnants. For the subset of thermonuclear events that are prolific producers of iron, we use published theoretical nucleosynthetic yields to identify a set of elemental abundance ratios infrequently observed in metal-poor stars but shared across a range of progenitor systems and explosion mechanisms: [Na

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Reeves, Zachary, Kevin C. Schlaufman, and Henrique Reggiani. "The Dependence of Iron-rich Metal-poor Star Occurrence on Galactic Environment Supports an Origin in Thermonuclear Supernova Nucleosynthesis." Astronomical Journal 166, no. 3 (2023): 127. http://dx.doi.org/10.3847/1538-3881/ace68d.

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Abstract It has been suggested that a class of chemically peculiar metal-poor stars called iron-rich metal-poor (IRMP) stars formed from molecular cores with metal contents dominated by thermonuclear supernova nucleosynthesis. If this interpretation is accurate, then IRMP stars should be more common in environments where thermonuclear supernovae were important contributors to chemical evolution. Conversely, IRMP stars should be less common in environments where thermonuclear supernovae were not important contributors to chemical evolution. At constant [Fe/H] ≲ −1, the Milky Way’s satellite cla

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Hambsch, F. J., S. Oberstedt, S. Zeynalov, et al. "Fission Research at IRMM." EPJ Web of Conferences 2 (2010): 07002. http://dx.doi.org/10.1051/epjconf/20100207002.

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11

Stollings, Lindsay, Binfeng Lu, and Yan Xu. "Immunomodulation of volatile anesthetics (IRM9P.726)." Journal of Immunology 192, no. 1_Supplement (2014): 128.9. http://dx.doi.org/10.4049/jimmunol.192.supp.128.9.

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Abstract Introduction: The impact of anesthetic exposure on the immune system is relatively unknown at both mechanistic and clinical levels. In this in vitro study, we employ immunological assays and understanding of immune cell function to evaluate the effect of volatile anesthetic (VA) exposure on bone marrow dendritic cells (BMDCs). BMDCc play a critical role in antigen presentation and link the innate and adaptive arms of the immune response. Hypothesis: We believe that VA exposure may modulate immune responses, specifically BMDC function. Methods: Bone marrow cells were harvested from C57

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Hult, Mikael, Timotheos Altzitzoglou, Bruno Denecke, Leif Persson, Goedele Sibbens, and Dietmar F. G. Reher. "Standardisation of 204Tl at IRMM." Applied Radiation and Isotopes 52, no. 3 (2000): 493–98. http://dx.doi.org/10.1016/s0969-8043(99)00200-6.

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Ostermann, Markus, Michael Berglund, P. Taylor, and M. Máriássy. "Certification of the chlorine content of the isotopic reference materials IRMM-641 and IRMM-642." Fresenius’ Journal of Analytical Chemistry 371, no. 6 (2001): 721–25. http://dx.doi.org/10.1007/s002160101015.

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Lamberty, A., and H. Emons. "Reference materials: from CBNM to IRMM." Accreditation and Quality Assurance 16, no. 8-9 (2011): 393–98. http://dx.doi.org/10.1007/s00769-011-0781-2.

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15

Richter, S., S. Konegger-Kappel, S. F. Boulyga, G. Stadelmann, A. Koepf, and H. Siegmund. "Linearity testing and dead-time determination for MC-ICP-MS ion counters using the IRMM-072 series of uranium isotope reference materials." Journal of Analytical Atomic Spectrometry 31, no. 8 (2016): 1647–57. http://dx.doi.org/10.1039/c6ja00203j.

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Hawse, WIlliam, Natasa Miskov-Zivanov, James Faeder, and Penelope Morel. "PTEN regulates CD4+ T cell differentiation (IRM6P.716)." Journal of Immunology 192, no. 1_Supplement (2014): 63.8. http://dx.doi.org/10.4049/jimmunol.192.supp.63.8.

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Abstract Naïve CD4+ T cells differentiate into either helper (Th) or regulatory (Treg) cells following encounter with antigen. T cell fate is in part determined by signaling strength where lower TCR and AKT/mTOR signaling favors Treg differentiation and higher TCR and AKT/mTOR signaling drives Th differentiation. AKT/mTOR signaling is regulated by PTEN, a phosphatase that is highly expressed in Tregs. We recently published a computational model that suggested a critical role for PTEN in T cell differentiation. Our current work focuses on validating the model predictions and explaining how PTEN

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Simon, Bolton, Lusted Caitlin, Taylor Bethany, and Tod Angela. "75 Improving Research Access for Mesothelioma Patients (IRAMP)." Lung Cancer 200 (February 2025): 108185. https://doi.org/10.1016/j.lungcan.2025.108185.

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18

König, Jan C. L. "https://econjournals.com/index.php/irmm/article/view/10187." International Review of Management and Marketing 10, no. 5 (2020): 127–37. http://dx.doi.org/10.32479/irmm.10187.

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Hambsch, F. J., S. Oberstedt, A. Al-Adil, et al. "Investigation of the Fission Process at IRMM." Journal of the Korean Physical Society 59, no. 2(3) (2011): 1654–59. http://dx.doi.org/10.3938/jkps.59.1654.

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20

Lamberty, A., G. Lapitajs, L. Van Nevel, et al. "The IRMM—International Measurement Evaluation Program (IMEP)." Biological Trace Element Research 43-45, no. 1 (1994): 571–83. http://dx.doi.org/10.1007/bf02917360.

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21

Lamberty, A., L. Van Nevel, J. R. Moody, and P. De Bièvre. "The IRMM - International Measurement Evaluation Programme, IMEP." Accreditation and Quality Assurance 1, no. 2 (1996): 71–82. http://dx.doi.org/10.1007/s007690050038.

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Pauwels, Jean. "Latest news on BCR/IRMM reference materials." Accreditation and Quality Assurance 6, no. 7 (2001): 328–29. http://dx.doi.org/10.1007/s007690100355.

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23

Dragomir, Florin, Paul Ciprian Patic, and Otilia Elena Dragomir. "Intelligent Robot with Microcontroller for Obstacles Avoiding." Solid State Phenomena 166-167 (September 2010): 179–84. http://dx.doi.org/10.4028/www.scientific.net/ssp.166-167.179.

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The paper describes a intelligent robot with two stepper motor and microcontroller PIC16F84A for obstacles avoiding (IRSMP). An experimental prototype, based on a stepper motor, microcontroller PIC16F84A and infrared sensors, has been realized using conventional digital circuits. The proposed control scheme can be usefully applied to any intelligent robot. The infrared sensors has using for obstacles avoiding. The program for microcontroller is making in assembler language.

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Hutchinson, John, and Vicky Dunn. "Development of the community based individual risk mitigation profile (IRMP) for people who have intellectual disability and are at risk of offending." Journal of Intellectual Disabilities and Offending Behaviour 7, no. 2 (2016): 66–74. http://dx.doi.org/10.1108/jidob-09-2015-0033.

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Purpose – The purpose of this paper is to discuss the development of the community-based individual risk mitigation profile (IRMP) and to examine its effectiveness for people who have an intellectual disability, and are at risk of offending, through the use of a case study. Design/methodology/approach – Case study and literature review. Findings – The tool has been found to be useful and accessible by clinicians. It has a particular focus on joint sharing of opinion on risk and decision making in a structured and contained multi-disciplinary forum, that is evidence-based and defensible. This m

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Hurtado-Bermúdez, Santiago, та José Luis Mas. "Determination of 210Po in low-level wild bilberries reference material for quality control assurance in environmental analysis using extraction chromatography and α-particle spectroscopy". Radiochimica Acta 108, № 2 (2020): 99–103. http://dx.doi.org/10.1515/ract-2019-3141.

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AbstractCertified reference materials (CRM) are being widely used for quality control assurance in environmental analysis. For certain CRM, the analytes and/or the range of concentrations are not be available or certified at all. The Joint Research Centre – Institute for Reference Materials and Measurements (JRC-IRMM) of the European Commission has issued a CRM of Wild Berries (IRMM-426) in order to validate radionuclide measurement methods for activity concentrations of the natural radionuclide 40K and the anthropogenic nuclides 90Sr and 137Cs, but not for 210Po. The aim of the work was to de

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Gupta, Neetu, Debasis Pore, Neetha Parameswaran, et al. "Ezrin tunes the magnitude of humoral immunity. (IRM8P.709)." Journal of Immunology 192, no. 1_Supplement (2014): 127.10. http://dx.doi.org/10.4049/jimmunol.192.supp.127.10.

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Abstract Ezrin is a member of the Ezrin-Radixin-Moesin (ERM) family of membrane-actin cytoskeleton crosslinkers that participate in a variety of cellular processes. In B cells, phosphorylation of ezrin at different sites regulates multiple processes such as lipid raft coalescence, BCR diffusion, microclustering, and endosomal JNK activation. In this study, we generated mice with conditional deletion of ezrin in the B cell lineage to investigate the physiological significance of ezrin’s function in antigen receptor-mediated B cell activation and humoral immunity. B cell development, as well as

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Poltorak, Alexander, Bridget Larkin, Guy Surpris, and Vladimir Ilyuha. "The role of STING in T lymphocytes (IRM5P.643)." Journal of Immunology 194, no. 1_Supplement (2015): 59.8. http://dx.doi.org/10.4049/jimmunol.194.supp.59.8.

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Abstract The cytoplasmic protein Stimulator of Interferon Genes (STING) plays an essential role in sensing intracellular pathogens and initiating type I IFN responses in myeloid cells. STING detects the presence of cytoplasmic DNA presented by various DNA-binding proteins (e.g. IFI16, DDX41, DAI, RNA Pol III); it also directly binds cyclic dinucleotides produced by intracellular bacteria or by the DNA-binding cyclic GAMP synthase (c-GAS). Once activated, STING phosphorylates TBK1 and IRF3 to trigger type I IFN production. To date STING has only been studied in macrophages and dendritic cells,

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Shu, Qiang, Chi Chen, Dongyan Zhao, Xiwang Liu, QiXing Chen, and XiangMing Fang. "TRIM22 enhances staurosporine-induced apoptosis in monocytes (IRM7P.492)." Journal of Immunology 192, no. 1_Supplement (2014): 126.17. http://dx.doi.org/10.4049/jimmunol.192.supp.126.17.

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Abstract Background TRIM22 was first identified as an interferon-induced gene, and constitutively expressed in peripheral blood leukocytes and lymphoid tissues, especially expressed at high levels in monocytes. Researches suggest that TRIM22 may have an impact on monocyte fate in immune response. However, the direct evidence of TRIM22 on monocyte apoptosis remains absent. Methods TRIM22 was constructed and transfected into a monocytic cell line THP-1 cell. Apoptosis of transfected cells was induced by STS and tested by flow cytometry. The caspase pathways involved in TRIM22-related apoptosis w

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Wang, Jinghua, Brian Manick, Guoping Wu, and Ruyi Hao. "Biofunctions of three new B7 family members (IRM7P.486)." Journal of Immunology 192, no. 1_Supplement (2014): 126.11. http://dx.doi.org/10.4049/jimmunol.192.supp.126.11.

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Abstract Recently, three new B7 family members, B7-H5 (VISTA, Gi24, or Dies1), B7-H6, and B7-H7 (HHLA2) were identified. However, the functions of the three new B7 family members remain uncertain. We expressed the human B7-H5, B7-H6, and B7-H7 extracellular domain human IgG1 Fc Chimera in mammalian cell line and investigated the functions of the purified recombinant B7-H5/Fc, B7-H6/Fc, and B7-H7/Fc in vitro. To determine the functions of B7-H5 and B7-H7, human T cells were treated with plate-bound anti-CD3 and either B7-H5/Fc, B7-H7/Fc or control IgG1 Fc. The cytokine levels of supernatant wer

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Kuhns, Michael, Mark Lee, Caleb Glassman, Neha Deshpande, and Heather Parrish. "Evidence for a pivot upon TCR engagement (IRM7P.700)." Journal of Immunology 194, no. 1_Supplement (2015): 61.1. http://dx.doi.org/10.4049/jimmunol.194.supp.61.1.

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Abstract The T cell receptor (TCR)-CD3 complex is the chief determinant for T cell development, activation, differentiation and the execution of effector functions. The TCR module (TCRα+TCRβ) relays highly specific information about antigenic peptides embedded within major histocompatibility complex molecules (pMHC) to the intracellular signaling domains of the associated CD3γε, CD3δε, and CD3ζζ signaling modules to initiate intracellular signaling. It is unclear how mechanical information is transferred from the TCR-pMHC interface, across the plasma membrane, and on to the intracellular signa

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Chernenko, Yuri, Olena Bielova, and Oleksandr Bielov. "Dynamic infrastructure risk management: real-world implementation and validation of the IRMM at Mastergaz." Економіка і регіон/ Economics and region, no. 2(97) (June 24, 2025): 130–38. https://doi.org/10.26906/eir.2025.2(97).3797.

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This study introduces and evaluates the Infrastructure Risk Management Method (IRMM), with particular emphasis on the Infrastructure Risk Index (IRI) as a quantitative measure to identify and mitigate risks in infrastructure projects. A two-year case study was conducted at Mastergaz, a leading infrastructure firm, involving fifty projects. Data were collected through structured interviews and surveys administered to project managers and field technicians. The IRI was calculated by integrating criticality, vulnerability, and external influences, and then analyzed in conjunction with historical

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Stolarz, Anna, Roger Eykens, Andre Moens, and Yetunde Aregbe. "Actinide target preparation at IRMM—then and now." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 613, no. 3 (2010): 351–56. http://dx.doi.org/10.1016/j.nima.2009.09.074.

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Kramer, G. N., J. Pauwels, L. Le Guern, H. Schimmel, and S. Trapmann. "Recent production of candidate reference materials at IRMM." Fresenius' Journal of Analytical Chemistry 370, no. 2-3 (2001): 142–46. http://dx.doi.org/10.1007/s002160100730.

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Varga, Zsolt, Célia Venchiarutti, Adrian Nicholl, et al. "IRMM-1000a and IRMM-1000b uranium reference materials certified for the production date. Part I: methodology, preparation and target characteristics." Journal of Radioanalytical and Nuclear Chemistry 307, no. 2 (2015): 1077–85. http://dx.doi.org/10.1007/s10967-015-4227-x.

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Richter, S., C. Venchiarutti, C. Hennessy, et al. "Preparation and certification of the uranium nitrate solution reference materials series IRMM-2019 to IRMM-2029 for the isotopic composition." Journal of Radioanalytical and Nuclear Chemistry 318, no. 2 (2018): 1359–68. http://dx.doi.org/10.1007/s10967-018-6166-9.

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Zhang, Jinyu, Zihai Li, and Beichu Guo. "ER stress-induced inflammasome activation promotes liver steatosis (IRM9P.723)." Journal of Immunology 192, no. 1_Supplement (2014): 128.6. http://dx.doi.org/10.4049/jimmunol.192.supp.128.6.

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Abstract Recent evidences suggest that obese animal exhibits increased endoplasmic reticulum (ER) stress and inflammation in the liver tissue. However, it is largely unknown how ER stress contributes to hepatic steatosis. In this study, we demonstrated that ER stress induced inflammasome activation and IL-1 beta production, leading to hepatic inflammation and steatosis. Our results show that tunicamycin (TM), an ER stress inducer, caused NLRP3 inflammasome activation, leading to increased IL-1 beta processing and production in macrophages and hepatocytes. We found that caspase-1 knockout (KO)

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Kumar, Satyendra, and Amy Kenter. "Immunoglobulin isotype switching during early B cell development (IRM8P.702)." Journal of Immunology 192, no. 1_Supplement (2014): 127.3. http://dx.doi.org/10.4049/jimmunol.192.supp.127.3.

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Abstract During B cell lymphopoiesis in the bone marrow (BM), V(D)J joining assembles immunoglobulin (Ig) VH and VL genes mediated by RAG recombinase. Mature splenic B cells undergo class switch recombination (CSR) and somatic hypermutation initiated by activation induced deaminase (AID). However, the strict ontological separation of these processes may breakdown under some circumstances. Several immunodeficiencies including Omenn syndrome display increased serum IgE despite undetectable numbers of B cells. We hypothesized that CSR occurs in BM pro- or pre-B cells. Earlier, we showed that Rag1

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Peron, Jean Pierre, Wesley Nogueira Brandão, Cristiano Rossato, and Niels Olsen Camara. "Glutamate ionotropic receptor (NMDAR) modulates T cell survival (IRM7P.712)." Journal of Immunology 194, no. 1_Supplement (2015): 61.13. http://dx.doi.org/10.4049/jimmunol.194.supp.61.13.

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Abstract Introduction: T cells play a crucial role in adaptive immune responses and neuroinflammatory diseases such as multiple sclerosis. Glutamate is one of the most abundant neurotransmitter in the central nervous system; it can acts through two different receptor families: metabotropic and ionotropic. It has been demonstrated that T cells can be the target of glutamate during antigen presentation and immunological synapses, however, little is known about its role on T cell survival. Methods and Results: To evaluate whether NMDAr ligands exert a role in T cell survival, we harvested spleen

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LEE, TAEYUN, Sungwook Lee, and Boyoun Park. "The nucleolus contains immune-related RNAs during infection. (IRM5P.644)." Journal of Immunology 194, no. 1_Supplement (2015): 59.9. http://dx.doi.org/10.4049/jimmunol.194.supp.59.9.

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Abstract The nucleolus is a subnuclear structure that is involved in ribosomal RNA (rRNA) synthesis and ribosome assembly, and it is also the location of viral replication or cellular stress sensing. However, the function of the nucleolus in the immune response is still unclear. Here, we report that the nucleoli are fused in both macrophages and dendritic cells during lipopolysaccharide (LPS) or CpG-DNA stimulation, which activates the Toll-like receptor 4 (TLR4) or Toll-like receptor 9 (TLR9) signaling pathway. Our results from RNA-sequencing analysis reveal that the nucleolus contains divers

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Tat, Connie, Ken Hayama, Hong Zan, and Paolo Casali. "Rad52 deficiency Increases immunoglobulin class switch DNA recombination (IRM8P.714)." Journal of Immunology 192, no. 1_Supplement (2014): 127.15. http://dx.doi.org/10.4049/jimmunol.192.supp.127.15.

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Abstract Class switch DNA recombination (CSR) plays a central role in the maturation of the antibody response. CSR entails the generation of double-strand DNA breaks (DSBs) mediated by activation-induced cytidine deaminase (AID). Resolution of these DSBs can occur through Ku70/Ku86 dependent classical non-homologous end-joining (C-NHEJ), or through an undefined alternative-end joining (A-EJ) that introduces microhomologies in the S-S junctions. Here we investigate the role of Rad52, an important DSB repair factor in CSR. We found that Rad52 deficiency elicits an increase in NP-specific IgG1 an

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Ponzevera, Emmanuel, Christophe R. Quétel, Michael Berglund, et al. "Mass discrimination during MC-ICPMS isotopic ratio measurements: Investigation by means of synthetic isotopic mixtures (IRMM-007 series) and application to the calibration of natural-like zinc materials (including IRMM-3702 and IRMM-651)." Journal of the American Society for Mass Spectrometry 17, no. 10 (2006): 1413–27. http://dx.doi.org/10.1016/j.jasms.2006.06.001.

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Pauwels, J., and M. Grasserbauer. "The view of IRMM on accreditation of CRM producers." Accreditation and Quality Assurance 7, no. 12 (2002): 516–19. http://dx.doi.org/10.1007/s00769-002-0515-6.

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Valkiers, S., T. Ding, K. Ruße, P. De Bièvre, and P. D. P. Taylor. "Absolute sulfur isotope amount ratios in two batches of high purity SO2 gas: sulfur isotope reference materials IRMM-2012 and IRMM-2013." International Journal of Mass Spectrometry 242, no. 2-3 (2005): 303–8. http://dx.doi.org/10.1016/j.ijms.2004.11.021.

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Venchiarutti, C., Z. Varga, S. Richter, et al. "IRMM-1000a and IRMM-1000b: uranium reference materials certified for the production date based on the 230Th/234U radiochronometer. Part II: certification." Journal of Radioanalytical and Nuclear Chemistry 308, no. 1 (2015): 105–11. http://dx.doi.org/10.1007/s10967-015-4368-y.

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Oliveira, Adriano Teixeira de, Paloma de Almeida Rodrigues, Alexandre Mendes Ramos Filho, et al. "Levels of Total Mercury and Health Risk Assessment of Consuming Freshwater Stingrays (Chondrichthyes: Potamotrygoninae) of the Brazilian Amazon." International Journal of Environmental Research and Public Health 20, no. 21 (2023): 6990. http://dx.doi.org/10.3390/ijerph20216990.

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Mercury is an element with potential risk to fish and those who consume it. Thus, this study aimed to determine the levels of total mercury (THg), carry out a health risk assessment related to the consumption of the freshwater stingrays Potamotrygon motoro, and determine the physical and chemical properties of the water where stingrays occur. Stingrays of the species P. motoro were obtained from the Amazon River, and samples of the animals’ musculature were collected to determine THg levels. Risk assessment was conducted using pre-established formulas of estimated monthly intake (EMI), maximum

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Leong, Jeff, Stephanie Schneider, Ryan Sullivan, and Todd Fehniger. "PTEN regulates natural killer cell trafficking and effector functions (IRM7P.484)." Journal of Immunology 192, no. 1_Supplement (2014): 126.9. http://dx.doi.org/10.4049/jimmunol.192.supp.126.9.

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Abstract Phosphatase and tensin homolog (PTEN) is a critical negative regulator of the PI3 kinase pathway, members of which are essential for regulating natural killer (NK) cell signaling and activation. To evaluate whether PTEN was required for normal NK cell functions, we utilized a mouse model of NK specific PTEN deficiency (Ncr1iCre knockin x PTENflox). PTEN deletion resulted in significant loss of NK cells in the bone marrow and other lymphoid tissues, but markedly increased numbers within the peripheral blood and lung. Surprisingly, we observed near equivalent NK cell maturation within p

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Mohamed, Eslam, Henrique Lemos, Lei Huang, et al. "DNA sensing via STING regulates autoimmunity and tumor immunity. (IRM5P.648)." Journal of Immunology 194, no. 1_Supplement (2015): 59.13. http://dx.doi.org/10.4049/jimmunol.194.supp.59.13.

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Abstract The Stimulator of Interferon Genes (STING) is activated by cytosolic DNA sensors such as cyclic GMP-AMP Synthase (cGAS) to induce interferon type I (IFN-I). Dendritic cells (DCs) that engulf dying tumor cells incite anti-tumor T cell immunity by sensing tumor cell DNA to activate STING/IFN-I signaling. Paradoxically, we find that DNA sensing to activate STING/IFN-I signaling induces DCs to express indoleamine 2, 3 dioxygenase (IDO), which activates regulatory T cells (Tregs). Thus treatment with DNA nanoparticles (DNPs) or cyclic dinucleotides (CDNs) to activate STING attenuated Exper

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Schwerk, Johannes, Kerri Thomas, Lauren Aarreberg, Abigail Jarret, MeeAe Hong, and Ram Savan. "Post-transcriptional regulation of interferon lambda during viral infection (IRM5P.640)." Journal of Immunology 194, no. 1_Supplement (2015): 59.5. http://dx.doi.org/10.4049/jimmunol.194.supp.59.5.

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Abstract Interferon lambda (IFN-λ) has gained increasing attention recently as an important mediator of antiviral protection in hepatitis C virus (HCV) infection. Similar to many cytokines, we have shown that expression of IFNL is regulated on a post-transcriptional level. Interestingly, single nucleotide polymorphisms (SNPs) within the IFNL genes dictate the outcome of acute HCV infection and serve as a prognostic marker for therapy of chronic HCV infection. Previously, we demonstrated that a functional SNP (rs4803217) within the 3'-untranslated region (UTR) of IFNL3 affects transcript stabil

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Tang, Daolin, Rui Kang, Michael Lotze, and Herbert Zeh. "Endogenous HMGB1 prevents nuclear catastrophe and proinflammatory nucleosomal release (IRM9P.719)." Journal of Immunology 192, no. 1_Supplement (2014): 128.2. http://dx.doi.org/10.4049/jimmunol.192.supp.128.2.

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Abstract The mechanisms by which tissue injury alerts the immune system and drives a systemic inflammatory response syndrome remain unknown. Here we identify a high mobility group box 1 (HMGB1)-mediated nuclear regulatory mechanism for the control of the inflammatory response during tissue injury. We show that conditional knockout of HMGB1 within the pancreas, while benign without provocation, rendered mice dramatically more susceptible to experimental acute severe pancreatitis, as manifested by accelerated tissue injury and animal lethality. Deficiency of endogenous pancreatic HMGB1 led to ex

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Du, Xinwang, Chao Wu, Quan Liang, et al. "A Global-Scale Overlapping Pixels Calculation Method for Whisk-Broom Payloads with Multi-Module-Staggered Longlinear-Array Detectors." Remote Sensing 17, no. 3 (2025): 433. https://doi.org/10.3390/rs17030433.

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A multi-module staggered (MMS) long-linear-array (LLA) detector is presently recognized as an effective and widely adopted means of improving the field of view (FOV) of in-orbit optical line-array cameras. In particular, in terms of low-orbit whisk-broom payloads, the MMS LLA detector combined with the one-dimensional scanning mirror is capable of achieving both large-swath and high-resolution imaging. However, because of the complexity of the instantaneous relative motion model (IRMM) of the whisk-broom imaging mechanism, it is really difficult to determine and verify the actual numbers of ov

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