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1

Phoenix, Vernon R., Kurt O. Konhauser, and F. Grant Ferris. "Experimental study of iron and silica immobilization by bacteria in mixed Fe-Si systems: implications for microbial silicification in hot springs." Canadian Journal of Earth Sciences 40, no. 11 (November 1, 2003): 1669–78. http://dx.doi.org/10.1139/e03-044.

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The immobilization of silica and iron by the bacteria Bacillus subtilis was monitored in controlled microcosms to elucidate the role iron may play in aiding bacterial silicification in hot springs. Silica and iron immobilization was monitored as a function of bacterial concentration, iron concentration, and silica concentration (both undersaturated and oversaturated with respect to amorphous silica). Results demonstrate that bacterial cells do immobilize more Fe than bacteria-free systems in solutions with iron concentrations [Formula: see text]50 ppm Fe. However, as iron concentrations increa
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2

Kupka, Daniel, Michal Lovás, and Vladimir Šepelák. "Deferrization of Kaolinic Sand by Iron Oxidizing and Iron Reducing Bacteria." Advanced Materials Research 20-21 (July 2007): 130–33. http://dx.doi.org/10.4028/www.scientific.net/amr.20-21.130.

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Iron oxidizing bacteria Acidithiobacillus ferrooxidans, iron reducing bacteria Acidiphilium spp. and their mixture were applied for leaching of iron impurities from quartz sand. The bacterial leaching was carried out in order to decrease the amount of colouring iron oxides and to improve the technological properties of the raw material. Mineralogical analysis confirmed the presence of siderite, iron-bearing muscovite and various amorphous and crystalline forms of iron oxides occurring both free and coating siderite and quartz particles. Mössbauer spectroscopy revealed various oxidation and mag
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3

Tang, Kam W., and Hans-Peter Grossart. "Iron effects on colonization behavior, motility, and enzymatic activity of marine bacteria." Canadian Journal of Microbiology 53, no. 8 (August 2007): 968–74. http://dx.doi.org/10.1139/w07-059.

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Iron availability in the ocean has been shown to affect the growth and production of phytoplankton and free-living bacteria. A large fraction of marine bacteria are specialized in colonizing and living on particles and aggregates, but the effects of iron limitation on these bacteria are not fully known. We conducted laboratory experiments to study the effects of iron availability on particle colonization behavior, motility, and enzymatic activities of 4 strains of marine bacteria. Iron depletion reduced the bacterial particle colonization rate by 1.7%–43.1%, which could be attributed to reduce
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4

Page, Malcom G. P. "The Role of Iron and Siderophores in Infection, and the Development of Siderophore Antibiotics." Clinical Infectious Diseases 69, Supplement_7 (November 13, 2019): S529—S537. http://dx.doi.org/10.1093/cid/ciz825.

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Abstract Iron is an essential nutrient for bacterial growth, replication, and metabolism. Humans store iron bound to various proteins such as hemoglobin, haptoglobin, transferrin, ferritin, and lactoferrin, limiting the availability of free iron for pathogenic bacteria. However, bacteria have developed various mechanisms to sequester or scavenge iron from the host environment. Iron can be taken up by means of active transport systems that consist of bacterial small molecule siderophores, outer membrane siderophore receptors, the TonB-ExbBD energy-transducing proteins coupling the outer and the
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5

Tang, Yu Lan, Wei Bin Wu, Ya Ting He, Jin Xiang Fu, and Xiao Lan Wang. "Low-Temperature Domestication of an Iron and Manganese Oxidizing Bacteria." Advanced Materials Research 374-377 (October 2011): 826–30. http://dx.doi.org/10.4028/www.scientific.net/amr.374-377.826.

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Abstract.One superior iron and manganese bacteria were separated from the stable operation of porcelain granular BAF filters of removing iron, manganese and ammonia. The bacteria was domesticated at low temperature. By analyzing the sample water containing iron and manganese in the role of iron and manganese bacteria which was not domesticated and domesticated at different temperature, observing the Iron and manganese concentration with time going on, studying the bacteria’s removal of iron and manganese property and the domesticated effect. Studies show that: the selected bacteria with 1% bac
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6

Xing, Weijia, Yue Zhan, Lei Yang, and Lei Yan. "Iron Biomineralization Performed by Iron-Cycling Bacteria and Magnetotactic Bacteria." ACTA SCIENTIFIC MICROBIOLOGY 1, no. 3 (March 1, 2018): 28–29. http://dx.doi.org/10.31080/asmi.2018.01.0024.

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7

Kuznetsova, D. A., V. A. Rykova, and O. N. Podladchikova. "Bacterial Siderophores: Structure, Functions, and Role in the Pathogenesis of Infections." Problems of Particularly Dangerous Infections, no. 3 (October 29, 2022): 14–22. http://dx.doi.org/10.21055/0370-1069-2022-3-14-22.

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This review systematizes and analyzes the data published over the past decade, devoted to the study of low-molecular-weight high affinity iron chelators – siderophores. Siderophores, which are found in bacteria, fungi and mammals, are able to extract iron from insoluble inorganic compounds, and in the host organism – from complexes with proteins that perform the function of nonspecific protection of mammals from infections. The extracted iron is delivered to cells through surface protein receptors specific for each siderophore, as well as various protein transport systems that make up membrane
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8

Ebrahiminezhad, Alireza, Zahra Manafi, Aydin Berenjian, Sedigheh Kianpour, and Younes Ghasemi. "Iron-Reducing Bacteria and Iron Nanostructures." Journal of Advanced Medical Sciences and Applied Technologies 3, no. 1 (May 22, 2017): 9. http://dx.doi.org/10.18869/nrip.jamsat.3.1.9.

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9

Liu, Zhuoming, Scott Reba, Wei-Dong Chen, Suheel Kumar Porwal, W. Henry Boom, Robert B. Petersen, Roxana Rojas, Rajesh Viswanathan, and L. Devireddy. "Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection." Journal of Experimental Medicine 211, no. 6 (May 26, 2014): 1197–213. http://dx.doi.org/10.1084/jem.20132629.

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Competition for iron influences host–pathogen interactions. Pathogens secrete small iron-binding moieties, siderophores, to acquire host iron. In response, the host secretes siderophore-binding proteins, such as lipocalin 24p3, which limit siderophore-mediated iron import into bacteria. Mammals produce 2,5-dihydroxy benzoic acid, a compound that resembles a bacterial siderophore. Our data suggest that bacteria use both mammalian and bacterial siderophores. In support of this idea, supplementation with mammalian siderophore enhances bacterial growth in vitro. In addition, mice lacking the mamma
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10

Akinbosede, Daniel, Robert Chizea, and Stephen A. Hare. "Pirates of the haemoglobin." Microbial Cell 9, no. 4 (April 4, 2022): 84–102. http://dx.doi.org/10.15698/mic2022.04.775.

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Not all treasure is silver and gold; for pathogenic bacteria, iron is the most precious and the most pillaged of metallic elements. Iron is essential for the survival and growth of all life; however free iron is scarce for bacteria inside human hosts. As a mechanism of defence, humans have evolved ways to store iron so as to render it inaccessible for invading pathogens, such as keeping the metal bound to iron-carrying proteins. For bacteria to survive within humans, they must therefore evolve counters to this defence to compete with these proteins for iron binding, or directly steal iron from
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11

Timofeeva, Anna M., Maria R. Galyamova, and Sergey E. Sedykh. "Bacterial Siderophores: Classification, Biosynthesis, Perspectives of Use in Agriculture." Plants 11, no. 22 (November 12, 2022): 3065. http://dx.doi.org/10.3390/plants11223065.

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Siderophores are synthesized and secreted by many bacteria, yeasts, fungi, and plants for Fe (III) chelation. A variety of plant-growth-promoting bacteria (PGPB) colonize the rhizosphere and contribute to iron assimilation by plants. These microorganisms possess mechanisms to produce Fe ions under iron-deficient conditions. Under appropriate conditions, they synthesize and release siderophores, thereby increasing and regulating iron bioavailability. This review focuses on various bacterial strains that positively affect plant growth and development through synthesizing siderophores. Here we di
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12

RAWLS, REBECCA. "Pumping Iron, Bacteria-style." Chemical & Engineering News Archive 80, no. 9 (March 4, 2002): 13. http://dx.doi.org/10.1021/cen-v080n009.p013a.

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13

Budzikiewicz, Herbert. "Iron Acquisition and Iron Transport by Bacteria." Frontiers in Natural Product Chemistry 1, no. 1 (January 1, 2005): 89–98. http://dx.doi.org/10.2174/1574089054583786.

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14

Mathews, Salima, Ranjeet Kumar, and Marc Solioz. "Copper Reduction and Contact Killing of Bacteria by Iron Surfaces." Applied and Environmental Microbiology 81, no. 18 (July 6, 2015): 6399–403. http://dx.doi.org/10.1128/aem.01725-15.

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ABSTRACTThe well-established killing of bacteria by copper surfaces, also called contact killing, is currently believed to be a combined effect of bacterial contact with the copper surface and the dissolution of copper, resulting in lethal bacterial damage. Iron can similarly be released in ionic form from iron surfaces and would thus be expected to also exhibit contact killing, although essentially no contact killing is observed by iron surfaces. However, we show here that the exposure of bacteria to iron surfaces in the presence of copper ions results in efficient contact killing. The proces
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15

Zhu, Mingang, Marianne Valdebenito, Günther Winkelmann, and Klaus Hantke. "Functions of the siderophore esterases IroD and IroE in iron-salmochelin utilization." Microbiology 151, no. 7 (July 1, 2005): 2363–72. http://dx.doi.org/10.1099/mic.0.27888-0.

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The siderophore salmochelin is produced under iron-poor conditions by Salmonella and many uropathogenic Escherichia coli strains. The production of salmochelin, a C-glucosylated enterobactin, is dependent on the synthesis of enterobactin and the iroBCDEN gene cluster. An E. coli IroD protein with an N-terminal His-tag cleaved cyclic salmochelin S4 to the linear trimer salmochelin S2, the dimer salmochelin S1, and the monomers dihydroxybenzoylserine and C-glucosylated dihydroxybenzoylserine (salmochelin SX, pacifarinic acid). The periplasmic IroE protein was purified as a MalE–IroE fusion prote
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16

Osadebe, Anwuli U., Dorcas C. Olorondu, and Gideon C. Okpokwasili. "Environmental and Microbial Influences on Corrosion of Selected Types of Petroleum Industry Steel." Environment and Natural Resources Journal 19, no. 4 (June 1, 2021): 310–19. http://dx.doi.org/10.32526/ennrj/19/2021004.

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This study explored the influence of brackish water sediment, mangrove swamp sediment, clayey/lateritic soil, and river water (freshwater) sediment on the corrosion rates of carbon, mild, and stainless steels and the species of sulphate reducing bacteria (SRB) and iron bacteria associated with the process. The material loss following burial of the steel samples for a 9-month period was assessed. Standard and specialised microbiological techniques were employed in the characterisation of the bacterial species. Qualitative assessment for corrosion was done via optical microscopy and macroscopy.
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17

Finlayson-Trick, Emma CL, Jordie AJ Fischer, David M. Goldfarb, and Crystal D. Karakochuk. "The Effects of Iron Supplementation and Fortification on the Gut Microbiota: A Review." Gastrointestinal Disorders 2, no. 4 (September 26, 2020): 327–40. http://dx.doi.org/10.3390/gidisord2040030.

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Iron supplementation and fortification are used to treat iron deficiency, which is often associated with gastrointestinal conditions, such as inflammatory bowel disease and colorectal cancer. Within the gut, commensal bacteria contribute to maintaining systemic iron homeostasis. Disturbances that lead to excess iron promote the replication and virulence of enteric pathogens. Consequently, research has been interested in better understanding the effects of iron supplementation and fortification on gut bacterial composition and overall gut health. While animal and human trials have shown seeming
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18

Golonka, Rachel, Beng San Yeoh, and Matam Vijay-Kumar. "The Iron Tug-of-War between Bacterial Siderophores and Innate Immunity." Journal of Innate Immunity 11, no. 3 (2019): 249–62. http://dx.doi.org/10.1159/000494627.

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Iron is necessary for the survival of almost all aerobic organisms. In the mammalian host, iron is a required cofactor for the assembly of functional iron-sulfur (Fe-S) cluster proteins, heme-binding proteins and ribonucleotide reductases that regulate various functions, including heme synthesis, oxygen transport and DNA synthesis. However, the bioavailability of iron is low due to its insolubility under aerobic conditions. Moreover, the host coordinates a nutritional immune response to restrict the accessibility of iron against potential pathogens. To counter nutritional immunity, most commen
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19

Appenzeller, Brice M. R., Carolina Yañez, Frederic Jorand, and Jean-Claude Block. "Advantage Provided by Iron for Escherichia coli Growth and Cultivability in Drinking Water." Applied and Environmental Microbiology 71, no. 9 (September 2005): 5621–23. http://dx.doi.org/10.1128/aem.71.9.5621-5623.2005.

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ABSTRACT The presence of iron, used both as a nutrient and as an electron acceptor, was demonstrated to give an advantage to Escherichia coli bacteria in drinking water. Slight additions of ferrous sulfate to water with initial low iron concentrations led to a significant increase in the number of E. coli bacteria. The presence of ferric oxide in water under anaerobic conditions increased bacterial cultivability.
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20

Ong, Cheryl-Lynn Y., Adam J. Potter, Claudia Trappetti, Mark J. Walker, Michael P. Jennings, James C. Paton, and Alastair G. McEwan. "Interplay between Manganese and Iron in Pneumococcal Pathogenesis: Role of the Orphan Response Regulator RitR." Infection and Immunity 81, no. 2 (November 26, 2012): 421–29. http://dx.doi.org/10.1128/iai.00805-12.

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ABSTRACTStreptococcus pneumoniae(the pneumococcus) is a major human pathogen that is carried asymptomatically in the nasopharynx by up to 70% of the human population. Translocation of the bacteria into internal sites can cause a range of diseases, such as pneumonia, otitis media, meningitis, and bacteremia. This transition from nasopharynx to growth at systemic sites means that the pneumococcus needs to adjust to a variety of environmental conditions, including transition metal ion availability. Although it is an important nutrient, iron potentiates oxidative stress, and it is established that
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21

Luptakova, Alena, and E. Macingova. "Sorption of Copper Ions by Biogenic Iron Sulphides." Advanced Materials Research 20-21 (July 2007): 631–34. http://dx.doi.org/10.4028/www.scientific.net/amr.20-21.631.

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Biogenic iron sulphides are excellent adsorbents for various heavy metals ions. Consequently, they have practical application for the elimination of heavy metals from waste waters. One of the principles for the iron sulphides preparation is the application of sulphatereducing bacteria. This biological-chemical method is based on the ability of these bacteria to reduce sulphates to hydrogen sulphide, which binds with the ferrous cations to form insoluble precipitates – iron sulphides. Under certain bacterial growth conditions biogenic iron sulphides can be magnetic. The aim of this work is to s
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22

Ahmed, Ayaz, and Shahana Kazmi. "Siderophore Production and its Role as Therapeutic Agent." Microbiological & Immunological Communications 1, no. 01 (December 31, 2022): 21–33. http://dx.doi.org/10.55627/mic.001.01.0181.

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Siderophores are iron chelators, which are produced by bacteria under iron-deficient conditions required for their growth. Therefore, siderophores can be used as a carrier to direct drugs into the bacteria and kill them. The present study was designed to screen siderophore production using different bacteria using an iron-deficient medium and its synergistic capability to kill drug-resistant bacteria. Siderophore under iron-deprived condition was evaluated by chrome azurol S (CAS) assay. Whereas, broth micro-dilution method and checkerboard assay were used to determine the antimicrobial proper
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23

Liu, Xing Yu, Ming Jiang Zhang, Yi Bin Li, Zi Ning Wang, and Jian Kang Wen. "In Situ Bioremediation of Tailings by Sulfate Reducing Bacteria and Iron Reducing Bacteria: Lab- and Field-Scale Remediation of Sulfidic Mine Tailings." Solid State Phenomena 262 (August 2017): 651–55. http://dx.doi.org/10.4028/www.scientific.net/ssp.262.651.

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To research the remediation efficiency of sulfate reducing bacteria and iron reducing bacteria on heavy metals, the remediation experiments of laboratory-scale and field-scale were conducted respectively with chalcopyrite tailings and 3 hectares lead-zinc sulfides mine tailings. The ion concentration of exudate was determined using inductively coupled plasma atomic emission spectroscopy, and key bacterial strains were investigated by real-time PCR. The laboratory-scale experiment of chalcopyrite tailings indicated pH of exudate rose to neutral, penetration time of exudate significantly increas
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Suzuki, Tomoko, Hideki Hashimoto, Nobuyuki Matsumoto, Mitsuaki Furutani, Hitoshi Kunoh, and Jun Takada. "Nanometer-Scale Visualization and Structural Analysis of the Inorganic/Organic Hybrid Structure of Gallionella ferruginea Twisted Stalks." Applied and Environmental Microbiology 77, no. 9 (March 4, 2011): 2877–81. http://dx.doi.org/10.1128/aem.02867-10.

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ABSTRACTThe so-called Fe/Mn-oxidizing bacteria have long been recognized for their potential to form extracellular iron hydroxide or manganese oxide structures in aquatic environments. Bacterial species belonging to the genusGallionella, one type of such bacteria, oxidize iron and produce uniquely twisted extracellular stalks consisting of iron oxide-encrusted inorganic/organic fibers. This paper describes the ultrastructure ofGallionellacells and stalks and the visualized structural and spatial localization of constitutive elements within the stalks. Electron microscopy with energy-dispersive
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25

Gehrer, Clemens M., Alexander Hoffmann, Richard Hilbe, Philipp Grubwieser, Anna-Maria Mitterstiller, Heribert Talasz, Ferric C. Fang, et al. "Availability of Ferritin-Bound Iron to Enterobacteriaceae." International Journal of Molecular Sciences 23, no. 21 (October 28, 2022): 13087. http://dx.doi.org/10.3390/ijms232113087.

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The sequestration of iron in case of infection, termed nutritional immunity, is an established strategy of host defense. However, the interaction between pathogens and the mammalian iron storage protein ferritin is hitherto not completely understood. To better characterize the function of ferritin in Gram-negative infections, we incubated iron-starved cultures of Salmonella Typhimurium and knockout mutant strains defective for major iron uptake pathways or Escherichia coli with horse spleen ferritin or ionic iron as the sole iron source. Additionally, we added bovine superoxide dismutase and p
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26

Chathoth, Kanchana, Louis Fostier, Bénédicte Martin, Christine Baysse, and Fabrice Mahé. "A Multi-Skilled Mathematical Model of Bacterial Attachment in Initiation of Biofilms." Microorganisms 10, no. 4 (March 23, 2022): 686. http://dx.doi.org/10.3390/microorganisms10040686.

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The initial step of biofilm formation is bacteria attachment to biotic or abiotic surfaces and other bacteria through intra or interspecies interactions. Adhesion can be influenced by physicochemical conditions of the environment, such as iron. There is no available mathematical model of bacterial attachment giving realistic initiation rather than random adhesion. We describe a simple stochastic attachment model, from the simplest case in two dimensions with one bacterial species attaching on a homogeneous flat surface to more complex situations, with either several bacterial species, inhomoge
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27

Miot, Jennyfer, Karim Benzerara, Martin Obst, Andreas Kappler, Florian Hegler, Sebastian Sch�dler, Camille Bouchez, Fran�ois Guyot, and Guillaume Morin. "Extracellular Iron Biomineralization by Photoautotrophic Iron-Oxidizing Bacteria." Applied and Environmental Microbiology 75, no. 17 (July 10, 2009): 5586–91. http://dx.doi.org/10.1128/aem.00490-09.

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ABSTRACT Iron oxidation at neutral pH by the phototrophic anaerobic iron-oxidizing bacterium Rhodobacter sp. strain SW2 leads to the formation of iron-rich minerals. These minerals consist mainly of nano-goethite (α-FeOOH), which precipitates exclusively outside cells, mostly on polymer fibers emerging from the cells. Scanning transmission X-ray microscopy analyses performed at the C K-edge suggest that these fibers are composed of a mixture of lipids and polysaccharides or of lipopolysaccharides. The iron and the organic carbon contents of these fibers are linearly correlated at the 25-nm sca
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Miot, Jennyfer, Karim Benzerara, Guillaume Morin, Andreas Kappler, Sylvain Bernard, Martin Obst, Céline Férard, et al. "Iron biomineralization by anaerobic neutrophilic iron-oxidizing bacteria." Geochimica et Cosmochimica Acta 73, no. 3 (February 2009): 696–711. http://dx.doi.org/10.1016/j.gca.2008.10.033.

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29

Saavedra, Albert, and Eduardo Cortón. "Leaching of Pyrite by Acidithiobacillus ferrooxidans Monitored by Electrochemical Methods." Solid State Phenomena 262 (August 2017): 541–44. http://dx.doi.org/10.4028/www.scientific.net/ssp.262.541.

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The aim of this work was to use electrochemical methods, capable to follow the corrosion of minerals, in order to monitor the progressive attack of the bacteria on the mineral. The assay was performed in a three electrode cell, with pyrite as the working electrode. The tests were performed in the absence and presence of iron; when present it was in low concentration. In order to compare the bacterial attack with other conditions, the study was conducted in three systems: live bacteria in culture media, dead bacteria in culture media, and sterile culture media, used as a control. The initial ba
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30

Guan, Le Luo, Kaneo Kanoh, and Kei Kamino. "Effect of Exogenous Siderophores on Iron Uptake Activity of Marine Bacteria under Iron-Limited Conditions." Applied and Environmental Microbiology 67, no. 4 (April 1, 2001): 1710–17. http://dx.doi.org/10.1128/aem.67.4.1710-1717.2001.

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ABSTRACT More than 60% of species examined from a total of 421 strains of heterotrophic marine bacteria which were isolated from marine sponges and seawater were observed to have no detectable siderophore production even when Fe(III) was present in the culture medium at a concentration of 1.0 pM. The growth of one such non-siderophore-producing strain, alpha proteobacterium V0210, was stimulated under iron-limited conditions with the addition of an isolated exogenous siderophore,N,N′-bis (2,3-dihydroxybenzoyl)-O-serylserine from aVibrio sp. Growth was also stimulated by the addition of three e
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Norton, Cheryl D., and Mark W. LeChevallier. "A Pilot Study of Bacteriological Population Changes through Potable Water Treatment and Distribution." Applied and Environmental Microbiology 66, no. 1 (January 1, 2000): 268–76. http://dx.doi.org/10.1128/aem.66.1.268-276.2000.

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ABSTRACT This pilot study compares the compositions of bacterial biofilms in pipe networks supplied with water containing either high levels of biodegradable organic matter (BOM) or low levels of BOM (conventionally or biologically treated, respectively). The Microbial Identification System for fatty acid analysis was utilized in this study to identify a large number of organisms (>1,400) to determine population changes in both conventionally and biologically treated water and biofilms. Data generated during this study indicated that suspended bacteria have little impact on biofilms, and de
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32

Schryvers, Anthony B., and Guido C. Gonzalez. "Receptors for transferrin in pathogenic bacteria are specific for the host's protein." Canadian Journal of Microbiology 36, no. 2 (February 1, 1990): 145–47. http://dx.doi.org/10.1139/m90-026.

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Transferrin receptors detected by a solid-phase binding assay were shown to be specific for the host's transferrin in the representative bacterial pathogens Neisseria meningitidis (human), Pasteurella haemolytica (bovine), and Actinobacillus pleuropneumoniae (porcine). Consistent with the receptor specificity, iron-deficient bacteria were only capable of utilizing transferrin from the host as a source of iron for growth. Key words: iron, transferrin, receptor.
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Arcos Arango, Yamilet, Judith Betancur Urhan, Gustavo Peñuela, and Néstor Jaime Aguirre. "Relationship between soluble forms of iron and manganese and the presence of oxidizing bacteria of both elements in the dam Riogrande II-Don Matías (Antioquia, Colombia)." Revista Facultad de Ingeniería Universidad de Antioquia, no. 55 (March 1, 2013): 45–54. http://dx.doi.org/10.17533/udea.redin.14713.

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From August 2006 to March 2008 presence of bacteria associated with the oxidation of iron and manganese was determined in the euphotic zone limit (LZF) and in the bottom of the hipolimnio (HF) in seven seasons of Riogrande II Dam reservoir depending on the availability of these metals. A water temperature, dissolved oxygen, pH, redox potential and electrical conductivity were measured in situ. At the bottom of hipolimnio with levels of dissolved oxygen ≤ 4 mgL-1 only were found iron oxidizing bacteria compatible with Gallionella sp, and Sphaerotilus sp, Beggiatoa sp . Final estimates for the b
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34

Arezes, João, Grace Jung, Victoria Gabayan, Erika Valore, Tomas Ganz, Yonca Bulut, and Elizabeta Nemeth. "Hepcidin-Induced Hypoferremia Is a Host-Defense Mechanism Against Siderophilic Bacteria." Blood 122, no. 21 (November 15, 2013): 176. http://dx.doi.org/10.1182/blood.v122.21.176.176.

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Abstract Introduction The iron-regulatory hormone hepcidin, a 25 amino acid peptide secreted by hepatocytes, is greatly increased during infection or inflammation, causing hypoferremia. Hypoferremia during infections has been proposed as a host defense mechanism that evolved to restrict iron availability for pathogen growth but specific support for this hypothesis has been lacking. Hereditary hemochromatosis, an iron overload disease caused by hepcidin deficiency, is associated with greatly increased risk of infections with siderophilic pathogens such as Vibrio vulnificus and Yersinia enteroco
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35

Poiata, Antoniea, Alexandru Vlahovici, Dorina-Emilia Creanga, and Petronela Tupu. "Fluorescent bacteria detecting iron loading." International Journal of Environmental Analytical Chemistry 85, no. 12-13 (October 15, 2005): 993–1000. http://dx.doi.org/10.1080/03067310500151235.

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36

Ratledge, Colin, and Lynn G. Dover. "Iron Metabolism in Pathogenic Bacteria." Annual Review of Microbiology 54, no. 1 (October 2000): 881–941. http://dx.doi.org/10.1146/annurev.micro.54.1.881.

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37

Pakulski, J. Dean, Richard B. Coffin, Cheryl A. Kelley, Sonya L. Holder, Roswell Downer, Peter Aas, M. Maille Lyons, and Wade H. Jeffrey. "Iron stimulation of Antarctic bacteria." Nature 383, no. 6596 (September 1996): 133–34. http://dx.doi.org/10.1038/383133b0.

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38

Yarlott, Nelson. "Iron Bacteria Still Bugging Operators." Opflow 26, no. 12 (December 2000): 3–11. http://dx.doi.org/10.1002/j.1551-8701.2000.tb02287.x.

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39

Prabhakar, Pranav Kumar. "Bacterial Siderophores and Their Potential Applications: A Review." Current Molecular Pharmacology 13, no. 4 (November 2, 2020): 295–305. http://dx.doi.org/10.2174/1874467213666200518094445.

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The bacterial infection is one of the major health issues throughout the world. To protect humans from the infection and infectious agents, it is important to understand the mechanism of interaction of pathogens along with their susceptible hosts. This will help us to develop a novel strategy for designing effective new drugs or vaccines. As iron is an essential metal ion required for all the living systems for their growth, as well, it is needed by pathogenic bacterial cells for their growth and development inside host tissues. To get iron from the host tissues, microbes developed an iron-che
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Sandrini, Sara M., Raminder Shergill, Jonathan Woodward, Remya Muralikuttan, Richard D. Haigh, Mark Lyte, and Primrose P. Freestone. "Elucidation of the Mechanism by Which Catecholamine Stress Hormones Liberate Iron from the Innate Immune Defense Proteins Transferrin and Lactoferrin." Journal of Bacteriology 192, no. 2 (October 9, 2009): 587–94. http://dx.doi.org/10.1128/jb.01028-09.

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ABSTRACT The ability of catecholamine stress hormones and inotropes to stimulate the growth of infectious bacteria is now well established. A major element of the growth induction process has been shown to involve the catecholamines binding to the high-affinity ferric-iron-binding proteins transferrin (Tf) and lactoferrin, which then enables bacterial acquisition of normally inaccessible sequestered host iron. The nature of the mechanism(s) by which the stress hormones perturb iron binding of these key innate immune defense proteins has not been fully elucidated. The present study employed ele
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Patel, Priyanka, Shreyas Bhatt, Hardik Patel, and Meenu Saraf. "Iron chelating bacteria: a carrier for biofortification and plant growth promotion." Journal of Biological Studies 3, no. 3 (December 1, 2020): 111–20. http://dx.doi.org/10.62400/jbs.v3i3.5309.

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Biofortification is the process by which the nutritional quality of food crops is improved through agronomic practices, conventional plant breeding, or modern biotechnology to focus on malnourishment in developing countries. Under iron restricted environment certain bacteria (iron chelating bacteria) produced iron chelating molecules called as siderophore. This review gives an overview of Need for biofortification, Plant growth promoting rhizobacteria, Plant growth promoting consortia, importance of iron for human health, uptake of iron in plants, iron chelating (siderophore producing) bacteri
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Corbari, L., M. A. Cambon-Bonavita, G. J. Long, F. Grandjean, M. Zbinden, F. Gaill, and P. Compère. "Iron oxide deposits associated with the ectosymbiotic bacteria in the hydrothermal vent shrimp Rimicaris exoculata." Biogeosciences Discussions 5, no. 2 (April 24, 2008): 1825–65. http://dx.doi.org/10.5194/bgd-5-1825-2008.

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Abstract. The Rimicaris exoculata shrimp is considered a primary consumer that dominates the fauna of most Mid-Atlantic Ridge (MAR) hydrothermal ecosystems. These shrimps harbour in their gill chambers an important ectosymbiotic community of chemoautotrophic bacteria associated with iron oxide deposits. The structure and elemental composition of the minerals associated with these bacteria have been investigated by using X-ray microanalyses, light microscopy, and transmission, environmental scanning and scanning transmission electron microscopy. The nature of the iron oxides in shrimps obtained
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Heinrichs, Jon H., LaVette E. Gatlin, Charles Kunsch, Gil H. Choi, and Mark S. Hanson. "Identification and Characterization of SirA, an Iron-Regulated Protein from Staphylococcus aureus." Journal of Bacteriology 181, no. 5 (March 1, 1999): 1436–43. http://dx.doi.org/10.1128/jb.181.5.1436-1443.1999.

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ABSTRACT The acquisition of iron by pathogenic bacteria is often a crucial step in establishing infection. To accomplish this, many bacteria, including Staphylococcus aureus, produce low-molecular-weight iron-chelating siderophores. However, the secretion and transport of these molecules in gram-positive organisms are poorly understood. The sequence, organization, and regulation of genes involved in siderophore transport are conserved among gram-negative bacteria. We used this information to identify a putative siderophore transport locus from an S. aureus genomic sequence database. This locus
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Goss, Christopher H., Yukihiro Kaneko, Lisa Khuu, Gail D. Anderson, Sumedha Ravishankar, Moira L. Aitken, Noah Lechtzin, et al. "Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections." Science Translational Medicine 10, no. 460 (September 26, 2018): eaat7520. http://dx.doi.org/10.1126/scitranslmed.aat7520.

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The lack of new antibiotics is among the most critical challenges facing medicine. The problem is particularly acute for Gram-negative bacteria. An unconventional antibiotic strategy is to target bacterial nutrition and metabolism. The metal gallium can disrupt bacterial iron metabolism because it substitutes for iron when taken up by bacteria. We investigated the antibiotic activity of gallium ex vivo, in a mouse model of airway infection, and in a phase 1 clinical trial in individuals with cystic fibrosis (CF) and chronicPseudomonas aeruginosaairway infections. Our results show that micromol
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Anzaldi, Laura L., and Eric P. Skaar. "Overcoming the Heme Paradox: Heme Toxicity and Tolerance in Bacterial Pathogens." Infection and Immunity 78, no. 12 (August 2, 2010): 4977–89. http://dx.doi.org/10.1128/iai.00613-10.

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ABSTRACT Virtually all bacterial pathogens require iron to infect vertebrates. The most abundant source of iron within vertebrates is in the form of heme as a cofactor of hemoproteins. Many bacterial pathogens have elegant systems dedicated to the acquisition of heme from host hemoproteins. Once internalized, heme is either degraded to release free iron or used intact as a cofactor in catalases, cytochromes, and other bacterial hemoproteins. Paradoxically, the high redox potential of heme makes it a liability, as heme is toxic at high concentrations. Although a variety of mechanisms have been
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Li, Yongchao, Xiaoxian Hu, and Bozhi Ren. "Treatment of antimony mine drainage: challenges and opportunities with special emphasis on mineral adsorption and sulfate reducing bacteria." Water Science and Technology 73, no. 9 (February 1, 2016): 2039–51. http://dx.doi.org/10.2166/wst.2016.044.

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The present article summarizes antimony mine distribution, antimony mine drainage generation and environmental impacts, and critically analyses the remediation approach with special emphasis on iron oxidizing bacteria and sulfate reducing bacteria. Most recent research focuses on readily available low-cost adsorbents, such as minerals, wastes, and biosorbents. It is found that iron oxides prepared by chemical methods present superior adsorption ability for Sb(III) and Sb(V). However, this process is more costly and iron oxide activity can be inhibited by plenty of sulfate in antimony mine drai
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Al-Rawi, Marwa amin, Nada H. A. L. Al-Mudallal, and Ali A. Taha. "Iron Oxide Nanoparticles as Anti-Virulence Factors of Gram-positive and Gram-negative Bacteria." SAR Journal of Pathology and Microbiology 4, no. 04 (August 11, 2023): 48–57. http://dx.doi.org/10.36346/sarjpm.2023.v04i04.003.

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Background: Due to their extensive use in medical therapy, iron oxide nanoparticles have recently attracted the attention of researchers in the field of increasing multi-resistance properties in bacterial pathogens. Because iron oxide nanoparticles have a high specific surface area, they can interact with bacterial surface structures and exhibit significant antibacterial activity. Objective: The current work, determined the effect of a novel anti-virulence factor agent which was created from iron oxide nanoparticles against selected gram-positive and gram-negative variant bacterial strains tha
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Seppänen, Harri. "Biological Treatment of Groundwater in Basins with Floating Filters–II. The Role of Microorganisms in Floating Filters." Water Science and Technology 20, no. 3 (March 1, 1988): 185–87. http://dx.doi.org/10.2166/wst.1988.0097.

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The role of certain types of bacteria is quite decisive in the formation of iron and manganese precipitates. Bacteria and other organisms participate in the precipitation of soluble iron and manganese in many different ways. The production of hydrogen peroxide seems to be an important phase in the formation of the precipitates. Bacteria produce hydrogen peroxide as an intermediate or an end product of metabolic processes (Gorlenko etal., 1983). Iron and manganese bacteria are typical gradient organisms, growing in a sharp gradient between oxidized and reduced environments. Iron precipitating t
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Pi, Hualiang, and John D. Helmann. "Ferrous iron efflux systems in bacteria." Metallomics 9, no. 7 (2017): 840–51. http://dx.doi.org/10.1039/c7mt00112f.

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Terwilliger, Austen, Michelle C. Swick, Kathryn J. Pflughoeft, Andrei Pomerantsev, C. Rick Lyons, Theresa M. Koehler, and Anthony Maresso. "Bacillus anthracis Overcomes an Amino Acid Auxotrophy by Cleaving Host Serum Proteins." Journal of Bacteriology 197, no. 14 (May 11, 2015): 2400–2411. http://dx.doi.org/10.1128/jb.00073-15.

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ABSTRACTBacteria sustain an infection by acquiring nutrients from the host to support replication. The host sequesters these nutrients as a growth-restricting strategy, a concept termed “nutritional immunity.” Historically, the study of nutritional immunity has centered on iron uptake because many bacteria target hemoglobin, an abundant circulating protein, as an iron source. Left unresolved are the mechanisms that bacteria use to attain other nutrients from host sources, including amino acids. We employed a novel medium designed to mimic the chemical composition of human serum, and we show he
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