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1

Hu, Xiao, Sai Rui Ma, Yan Yan Wu, et al. "Antioxidant Activities of Tilapia (Oreochromis niloticus) Protein Hydrolysates-Iron Chelate Based on Properties of Biological Materials." Advanced Materials Research 700 (May 2013): 263–67. http://dx.doi.org/10.4028/www.scientific.net/amr.700.263.

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Tilapia (Oreochromis niloticus) protein was hydrolysed by papain, and then the tilapia (Oreochromis niloticus) protein hydrolysates (TPH) chelated with ferrous ions at various mass ratios of TPH to FeCl2 (5:1, 10:1 and 20:1) to obtain the biological materials of chelate I, chelate II and chelate III, respectively. The ferrous-binding rate and antioxidant activities of the chelates were investigated. It was found that the ferrous-binding rate increased with the increase of mass ratios (TPH/FeCl2) from 5:1 to 20:1. The DPPH radical scavenging activity and reducing power activity of chelate III w
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2

Nechiporenko, Ivan, Svetlana Akimova, Pavel Kazakov, Elena Nikulina, and Nina Tsirulnikova. "Screening of different Fe(III) and Fe(II) chelate complexes in clonal micropropagation technology of highbush blueberry (Vaccinium corymbosum L.)." BIO Web of Conferences 66 (2023): 02002. http://dx.doi.org/10.1051/bioconf/20236602002.

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The element iron plays a key role in plant physiology. For plant nutrition, chelated forms of iron are preferred. Therefore, in clonal micropropagation media, FeSO4 x 7H2O is usually introduced together with Na2EDTA. At the same time, other effective iron chelates with both carboxyl and phosphorus chelates are known. So far, there are few scientific studies on the effect of iron chelates complexes on blueberry plants under in vitro conditions. Therefore, studies were conducted with different iron chelate complexes in 4 concentrations on highbush blueberry (Vaccinium corymbosum L.) cv. Brigitta
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3

Martell, Arthur E., Ramunas J. Motekaitis, Dian Chen, Robert D. Hancock, and Derek McManus. "Selection of new Fe(III)/Fe(II) chelating agents as catalysts for the oxidation of hydrogen sulfide to sulfur by air." Canadian Journal of Chemistry 74, no. 10 (1996): 1872–79. http://dx.doi.org/10.1139/v96-210.

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The removal and oxidation to sulfur of H2S, contained in a broad range of sour gas streams including natural gas, by a Fe(III)/Fe(II) chelate system imposes several requirements on the iron chelate that is employed as the redox catalyst. The solution of the catalyst must be neutral or mildly alkaline to efficiently absorb H2S from the gas passed through the solution. The stability of the iron(III) chelate must be high enough that solid Fe(OH)3 not precipitate at the pH employed. Also the stability of the iron(II) chelate must be high enough to prevent the precipitation of FeS from the reaction
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4

Asil, Hasan. "Effects of Chelated Iron (Eddha-Fe) Treatments on Corm And Stigma Quality in Saffron (Crocus Sativus L.)." Bangladesh Journal of Botany 52, no. 1 (2023): 97–103. http://dx.doi.org/10.3329/bjb.v52i1.65239.

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Effects of different doses of chelated iron (EDDHA-Fe) on the yield and quality of saffron leaf, corm and stigma were investivated. The highest weight of harvested corms was obtained when treated with 2 g of iron chelate per corm, 366.57 g, and the highest number of corm was obtained when treated with 4 g of iron chelate per corm, 73.00 g. When the effects of the iron chelate treatments on the quality of the stigma studied, it was found that the treatment with 2 g of iron chelate per corm gave a yield of dry stigma 754.00 mg and the highest average amount of safranal of 1386.50 mg/kg. The trea
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5

Fan, Chaozhong, Xintong Wang, Xiwang Song, et al. "Identification of a Novel Walnut Iron Chelating Peptide with Potential High Antioxidant Activity and Analysis of Its Possible Binding Sites." Foods 12, no. 1 (2023): 226. http://dx.doi.org/10.3390/foods12010226.

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Peptide iron chelate is widely regarded as one of the best iron supplements for relieving iron deficiency. In this study, a new type of walnut peptide iron (WP-Fe) chelate was prepared using low molecular weight walnut peptides (WP) as raw materials. Under the conditions of this study, the chelation rate and iron content of the WP-Fe chelate were 71.87 ± 1.60% and 113.11 ± 2.52 mg/g, respectively. Fourier transform infrared spectroscopy (FTIR), zeta potential, amino acid composition, and other structural analysis showed that WP-Fe is formed by the combination of carboxyl, amino and carbonyl wi
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6

Subramani, Murali, Jawahar Durairaj, Chitdeshwari Thiyagarajan, and Jagadesh Muthumani. "Synthesis of iron chelates for remediation of iron deficiency in an alkaline and calcareous soil." Journal of Applied and Natural Science 13, SI (2021): 149–55. http://dx.doi.org/10.31018/jans.v13isi.2818.

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The present study was aimed to investigate the using iron chelates viz., ferrous glycinate and ferrous citrate for the remediation of iron deficiency in alkaline and calcareous soil. The lab experiment was carried out to study the synthesis of Fe chelates by using organic and amino acid based chelating agents. The Fe chelates were synthesized based on 2:1 molar ratio of chelating agents and metal ions. The synthesized iron chelate was characterized by using Fourier transform infrared spectrophotometer (FT-IR). Finally, the synthesized amino acid and organic acid chelated iron were used to reme
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7

Hertrampf and Olivares. "Iron Amino Acid Chelates." International Journal for Vitamin and Nutrition Research 74, no. 6 (2004): 435–43. http://dx.doi.org/10.1024/0300-9831.74.6.435.

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Iron amino acid chelates, such as iron glycinate chelates, have been developed to be used as food fortificants and therapeutic agents in the prevention and treatment of iron deficiency anemia. Ferrous bis-glycine chelate (FeBC), ferric tris-glycine chelate, ferric glycinate, and ferrous bis-glycinate hydrochloride are available commercially. FeBC is the most studied and used form. Iron absorption from FeBC is affected by enhancers and inhibitors of iron absorption, but to a lesser extent than ferrous sulfate. Its absorption is regulated by iron stores. FeBC is better absorbed from milk, wheat,
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8

I., Beshkenadze, Klarjeishvili N., M.Gogaladze, M.Tchikaidze, and Ts.Gabelia. "Synthesis and study of Arginin-containing iron and cobalt chelates." World Journal of Advanced Research and Reviews 21, no. 1 (2024): 2576–83. https://doi.org/10.5281/zenodo.13377664.

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Synthesis conditions have been established and arginin-containing iron and cobalt chelate compounds with general formula: Me(Arg)n(CH<sub>3</sub>COO)<sub>2</sub>&middot;mH<sub>2</sub>O, where Me = Fe, Co;&nbsp; Arg &ndash; neutral arginin molecule, n = 1&divide;3; m = 1&divide;4 have been synthesized. Synthesized chelates have been studied using a number of physical and chemical methods. In particular, the content has been established via trace element analysis, while individuality has been identified using melting temperature measurement and diffractographic method. According to study of qual
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9

Glinushkin, Alexey, Svetlana Akimova, Elena Nikulina, et al. "Preliminary Study: Micropropagation Using Five Types of Chelated Iron and the Subsequent Acclimation of Blue Honeysuckle (Lonicera caerulea var. kamtschatica Sevast.)." Forests 14, no. 4 (2023): 821. http://dx.doi.org/10.3390/f14040821.

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Blue honeysuckle (Lonicera caerulea var. kamtschatica Sevast.) is a valuable berry crop with a unique biochemical composition. It is rich in vitamins, minerals, and biologically active substances. Different species and cultivars of honeysuckle require different cultivation conditions in the field of accelerated reproduction in vitro. Taking into account the high clonal replication potential of the plant, we conducted research on the chelated-iron form’s influence on the micropropagation productivity of the blue honeysuckle “Lulia” cultivar at the multiplication, rooting, and subsequent acclima
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10

Volgin, Victor Vladimirovich, Vladimir Dmitrievich Bochkarev, Alexander Sergeevich Pyresev, Alexander Vasilievich Ivoilov, and Natalia Viktorovna Nikolaichenko. "The influence of chelated forms of micronutrients (Fe, Zn, Cu) on the productivity of amaranth." Agrarian Scientific Journal, no. 5 (May 3, 2025): 12–19. https://doi.org/10.28983/asj.y2025i5pp12-19.

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The article is devoted to studying the impact of chelate microfertilizers (iron, zinc, copper) on the productivity of Amaranth variety Voronezhskii 36 under the conditions of the southern Non-Chernozem region. Various methods of fertilizer application are considered, including foliar treatment and pre-sowing seed treatment. Field experiments were conducted during 2023-2024, taking into account the climatic characteristics of the region. The obtained data show that the use of chelate fertilizers contributes to an increase in amaranth yields when applying foliar feeding and a comprehensive appro
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11

Berg, Lisa C., and Henry R. Owen. "A Comparison between Synthetic and Organic Iron Chelators on in Vitro Growth of Nicotiana tabacum Callus Cultures." HortScience 31, no. 4 (1996): 630g—631. http://dx.doi.org/10.21273/hortsci.31.4.630g.

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Nicotiana tabacum callus growth (fresh weight) was measured after culture in the light (16-hour photoperiod) or in darkness for four different culture media, differing in iron chelate type or concentration. All media contained MS basal medium supplemented with 30 g·L–1 sucrose, 2 mg·L–1 IAA, 0.2 mg·L–1 KIN, and 7 g·L–1 agar, pH 5.8. Three of the media contained iron-metalosate (Albion Laboratories), an organic iron chelate, at 100, 200, and 400 micromolar concentrations, and the fourth medium contained 100 μm Fe-EDTA. Twenty-five culture tubes were prepared for each of the 4 different media co
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12

Thakulla, Dharti, and Paul R. Fisher. "Effects of Cold Plasma and Ozone Water Treatment on Micronutrient Solubility." Horticulturae 9, no. 5 (2023): 568. http://dx.doi.org/10.3390/horticulturae9050568.

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Cold plasma and ozone sanitation of irrigation solutions can oxidize both microbes and non-target micronutrients because their high oxidation-reduction potential (ORP) is a non-selective mode of action. The objective of this study was to evaluate the effects of cold plasma and ozone treatment on oxidation of iron and manganese in nutrient solutions containing one of four iron chelates (iron-ethylenediaminetetraacetic acid (Fe-EDTA), iron-diethylenetriaminepentaacetic acid (Fe-DTPA), iron-ethylenediamine-N,N′-bis(2-hydroxyphenylacetic acid) (Fe-EDDHA), and hydroxybenzyl ethylenediamine (Fe-HBED
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13

Blinov, A. V., A. V. Samovolov, A. S. Askerova, A. A. Nagdalyan, A. M. Serov, and M. B. Rebezov. "The influence of chelated iron-containing complex on the quality of fermented milk products." Agrarian science 1, no. 4 (2025): 159–66. https://doi.org/10.32634/0869-8155-2025-393-04-159-166.

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The aim of the work is to study the effect of an iron-containing chelate complex (iron ascorbate) on the physico-chemical, organoleptic and microbiological parameters of a fermented milk product. Iron ascorbate tonicotinate was synthesized by a mechanochemical method. The following reagents were used to obtain the complex: ascorbic acid, nicotinic acid, iron (II) sulfate, barium hydroxide 8-aqueous. As a result of studying the physicochemical characteristics, it was found that the introduction of iron ascorbate tonicotinate with different concentrations into the fermented milk product does not
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14

Albano, Joseph P., and William B. Miller. "Iron Chelate Photodegradation in Fertilizer and Nutrient Solutions Affect Iron Acquisition." HortScience 30, no. 4 (1995): 845F—845. http://dx.doi.org/10.21273/hortsci.30.4.845f.

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Iron chelate photodegradation is a problem in tissue culture where limited soluble Fe in agar reduces callus tissue growth. Our objectives were to determine if Fe chelate photodegradation occurs in commercial fertilizers used in greenhouse plant production and, if so, the effects on plant Fe acquisition. Commercial 20N–10P–20K soluble fertilizers containing Fe-EDTA were prepared as 100x stocks based on a 100 mg N/liter (1x) concentration. A modified Hoagland's solution with Fe-DTPA was prepared as a 10x stock based on a 200 mg N/liter (1x) concentration. Samples then were kept in darkness or w
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15

Olakanmi, Oyebode, Larry S. Schlesinger, Ambar Ahmed, and Bradley E. Britigan. "The Nature of Extracellular Iron Influences Iron Acquisition by Mycobacterium tuberculosis Residing within Human Macrophages." Infection and Immunity 72, no. 4 (2004): 2022–28. http://dx.doi.org/10.1128/iai.72.4.2022-2028.2004.

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ABSTRACT We have reported that Mycobacterium tuberculosis residing within the phagosomes of human monocyte-derived macrophages (MDM) can acquire Fe from extracellular transferrin (TF) and sources within the MDM. In the lung, Fe is also bound to lactoferrin (LF) and low-molecular-weight chelates. We therefore investigated the ability of intraphagosomal M. tuberculosis to acquire Fe from these sources. M. tuberculosis acquired 30-fold and 3-fold more Fe from LF and citrate, respectively, compared to TF, in spite of similar MDM-associated Fe. M. tuberculosis infection decreased MDM-associated Fe
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16

Azeez, Kharman S., and Shlier M. Taha. "Response Two Strawberry Cultivars (Fragaria × ananassa Duch.) for foliar Application of Algae and Iron chelate Fertilizers." Kirkuk University Journal For Agricultural Sciences 14, no. 3 (2023): 98–112. http://dx.doi.org/10.58928/ku23.14311.

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The beginning of this study in the seasons of 2021-2022 from the orchard at agricultural training center in Erbil /Ministry of Agriculture / Kurdistan Region/ Iraq, The experiment examines the impact of Algae and Iron Chelate at three doses on growth, blooming, and yield as a foliar spray and their interactions on growth, chemical composition, production, and quality of strawberry at two strawberry cultivars (Fragaria x ananassa Duch.). Festival and Sabrina, using the six spraying while doing the experiment in the morning start in November 10 2021 to January 1 2022. The results showed The effe
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17

Nishida, Yuzo, Yuuta Ito, and Takahiro Satoh. "Origin of Renal Proximal Tubular Injuries by Fe(III)-nta Chelate." Zeitschrift für Naturforschung C 62, no. 7-8 (2007): 608–12. http://dx.doi.org/10.1515/znc-2007-7-825.

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Interaction between apo-transferrin and several iron(III) chelates has been investigated in terms of the capillary electrophoresis method. Based on the results, it has been clarified that (i) a binuclear iron(III) unit with an oxo-bridge is necessary for the facile transfer of an iron atom from the iron(III) chelate to apo-transferrin, and (ii) the renal proximal tubular injuries by Fe(III)-nitrilotriacetate (Fe-nta) should be due to the unique binuclear structure of this complex, which gives a peroxide adduct of the binuclear Fe-nta in the presence of glutathione cycle and oxygen
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18

Razanova, O. P., G. M. Ohorodnichuk, T. L. Holubenko, et al. "Meat productivity and quality of meat and liver of broiler chickens after consuming diet with mineral supplements containing chelates of cuprum, iron, zinc, and manganese." Regulatory Mechanisms in Biosystems 15, no. 1 (2024): 159–65. http://dx.doi.org/10.15421/022423.

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Poultry farming plays an important role as a producer of high-quality animal protein, which can solve issues of protein deficit among the population. Genetic growth potential of broiler chickens can be maximized through regular supply of microelements, especially chelate aminoacids. Those compounds improve metabolic processes in the body and increase increments in live mass and slaughter-yield of meat. The main objective of the study was identifying effects of mineral supplements with chelate microminerals on meat productivity of broiler chickens, quality of breast and thigh muscles, and conte
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19

VIKASH KUMAR, DINESH KUMAR, Y.V. SINGH, and RISHI RAJ. "Effect of iron fertilization on dry-matter production, yield and economics of aerobic rice (Oryza sativa)." Indian Journal of Agronomy 60, no. 4 (2001): 547–53. http://dx.doi.org/10.59797/ija.v60i4.4491.

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A field experiment was conducted during the rainy (kharif) seasons of 2011 and 2012 at the research farm of the Indian Agricultural Research Institute, New Delhi, to study the effect of iron fertilization on dry-matter produc- tion, yield and economics of aerobic rice (Oryza sativa L.) varieties. The experiment was laid out in a randomized block design with 3 replications. Treatments comprised 2 rice varieties (PRH 10 and PS 5) and 8 sources and modes of iron fertilizationcontrol (no iron), iron sulphate @ 50 kg/ha + 1 foliar spray of 2.0% iron sulphate, iron sulphate @ 50 kg/ha + 1 foliar spr
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20

H. Mahdi, Hasan, Lamiaa A. Mutlag, and Raghad S. Mouhamad. "Study the effect of khazra iron nano chelate fertilizer foliar application on two rapeseed varieties." Bionatura 4, no. 2 (2019): 841–45. http://dx.doi.org/10.21931/rb/2019.04.02.4.

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An experiment was conducted in Al-zafraniya station / Baghdad – Iraq, during the winter season 2017 - 2018 in order to study the effect of khazra iron nano chelate fertilizer foliar application on two rapeseed varieties for increasing yield and yield components. The experiment designed by randomized complete blocks design (RCBD) for three replicates. The first factor included two rapeseed varieties (Brassica napus var. oleifera and Brassica napus L. var. pactol) and second factor included khazra iron nano chelated in three levels 0, 5 (kg.ha-1) (0.5 kg nano iron fertilizers per 1000-liter wate
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21

Heidari, M., I. Salmanpour, H. Ghorbani, and H. R. Asghari. "Iron Chelate and Rhizobactria Changed Growth, Grain Yield, and Physiological Characteristics in Maize." Scientia Agriculturae Bohemica 49, no. 4 (2018): 245–54. http://dx.doi.org/10.2478/sab-2018-0031.

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Abstract In order to investigate the effect of iron chelate and plant growth promoting rhizobacteria (PGPR) on maize, an experiment was conducted as completely randomized block factorial design with three replicates. The first factor included of bacterial strain: S1= Control (without use of bacteria), S2=Azotobacter chroococcum and S3= Azospirillum brasilens and the second factor included of iron chelate: F1= Control, F2= soil application of Fe chelate, F3= foliar application of Fe chelate, F4= soil application of nano Fe chelate and F5= foliar application of nano Fe chelate. The results showe
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22

GROSS, MAURICE, AGUS NURHADI, and ERNEST GRAF. "NEW IRON(II) CHELATE." Analytical Sciences 7, Supple (1991): 1421–26. http://dx.doi.org/10.2116/analsci.7.supple_1421.

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23

Ohorodnichuk, H., V. Zagamula, Y. Zagamula, and Y. Trembitskyi. "Killing indicators and quality of muscle tissue of pigs after administration of the drug “Kronocid-L” into the diet." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 26, no. 100 (2024): 70–74. http://dx.doi.org/10.32718/nvlvet-a10010.

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The effect of feeding the drug “Kronocid-L” with the content of chelated compounds of microelements on slaughter performance and the quality of muscle tissue of pigs was investigated. Chelate compounds, or chelates (from the English chelate – claw), belong to complex compounds that are formed as a result of the connection of a cation (metal ion) with two or more atoms of a complexon (ligand) molecule. Chelates are significantly different from non-chelated compounds both in terms of chemical and physical properties and in their effects on living organisms. A scientific and economic experiment w
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24

Koshchaev, A. G., N. E. Gorkovenko, A. V. Kosykh, and D. V. Antipova. "Chelate compounds and their use for correction of trace element deficiencies in livestock (review)." Veterinary Science Today 13, no. 2 (2024): 136–42. http://dx.doi.org/10.29326/2304-196x-2024-13-2-136-142.

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Livestock and poultry diseases occurring due to mineral or vitamin deficiencies are widely reported and belong to the factors restraining the development of livestock industry. Almost until the 90s of the last century, the conditions associated with trace element deficiency were prevented and treated using inorganic compounds. In recent decades, scientists have synthesized chelate metal compounds using organic carriers, determining the high bioavailability of these compounds and the efficiency that repeatedly exceeds the efficiency of inorganic compounds. Amino acids are preferably used as org
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25

D'Haese, P. C., L. V. Lamberts, and M. E. De Broe. "Indirect measurement of desferrioxamine and its chelated compounds aluminoxamine and ferrioxamine by Zeeman atomic absorption spectrometry." Clinical Chemistry 35, no. 5 (1989): 884–87. http://dx.doi.org/10.1093/clinchem/35.5.884.

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Abstract This indirect method for determination of desferrioxamine (DFO, deferoxamine, Desferal) and its chelated compounds ferrioxamine (FO) and aluminoxamine (AIO) in biological fluids involves metal chelate formation and solvent extraction, the metal being determined by Zeeman atomic absorption spectrometry (Zeeman-AAS). Special attention was paid to the pH and recovery of extraction, iron-aluminum interactions, extraction times and volumes, centrifugation rates, and instrument settings. Precautions were taken to avoid contamination with aluminum and iron and to prevent co-extraction of iro
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26

Puglisi, Ivana, Sergio Brida, Vasile Stoleru, Valentina Torino, Vincenzo Michele Sellitto, and Andrea Baglieri. "Application of Novel Microorganism-Based Formulations as Alternative to the Use of Iron Chelates in Strawberry Cultivation." Agriculture 11, no. 3 (2021): 217. http://dx.doi.org/10.3390/agriculture11030217.

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The strawberry is a low-growing, herbaceous perennial plant, sensitive to iron deficiency. The iron deficiency represents a nutritional disorder, leading to a decreased content of photosynthetic pigments, which determines the yellow color characteristic of chlorotic leaves. Therefore, in calcareous soils, the use of synthetic iron chelate is often mandatory in strawberry cultivation. The employment of novel microorganism-based formulations as alternatives to the use of iron chelates, was evaluated during strawberry cultivation by monitoring the morpho-biometric parameters, chlorophylls, the ir
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27

Mandecka, Anna, Anna Dąbrowska, Łukasz Bobak, and Marek Szołtysik. "Casein Hydrolysate and Casein–Iron Chelate as Natural Bioactive Compounds for Yoghurt Fortification." Applied Sciences 12, no. 24 (2022): 12903. http://dx.doi.org/10.3390/app122412903.

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The aim of the study was to apply the bioactive components casein hydrolysate and casein–iron chelate to yoghurt and to analyze their influence on product parameters. Casein was hydrolyzed with the non-commercial protease obtained from Yarrowia lipolytica yeast and subjected to chelating process with Fe2+ ions. Both preparations were introduced to yoghurt production as additives for elevation of dry matter by 2%. The control yoghurt was produced with the addition of skim milk powder. In the prepared experimental yoghurts, the content of dry matter [DM], protein, fat, as well as iron contents w
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28

BM, Brena, Ryden LG, and J. Porath. "Immobilization of beta‐galactosidase on metal‐chelate‐substituted gels." Biotechnology and Applied Biochemistry 19, no. 2 (1994): 217–31. http://dx.doi.org/10.1111/j.1470-8744.1994.tb00295.x.

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The use of copper, zinc, iron, nickel and calcium in three different chelating gels was investigated for preparing immobilized beta‐galactosidase. The chelated ligands [Cu(2+)‐iminodiacetate (IDA), Cu(2+)‐Tris(carboxymethyl)ethylenediamine (TED), Ni(2+)‐IDA and Fe(3+)‐IDA] absorbed the protein so strongly that it can be considered a true immobilization. The obtained enzyme derivatives were investigated with regard to activity and stability. Enzymic activity was highly preserved in general for the TED derivates (90% when compared with that for Cu(2+)‐TED). The immobilized Ni2+ derivatives were
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29

Garbowski, Maciej W., Amna Abdel-Gadir, James Moon, and John B. Porter. "Myocardial Hemosiderosis Correlates with Plasma NTBI Species That Represent Chelated Iron in Transfusion-Dependent Thalassemia." Blood 128, no. 22 (2016): 203. http://dx.doi.org/10.1182/blood.v128.22.203.203.

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Abstract Introduction In transfusion dependent thalassemias (TDT), plasma risk factors predicting myocardial hemosiderosis (MH) are needed. High labile plasma iron (LPI) and non-transferrin bound iron (NTBI, in its various species) may increase MH risk, so could be blood biomarkers, but the clinical utility seems unclear (Garbowski et al. 2015 Blood). This is partly due to the characteristics of the LPI assay and the two NTBI assays: the NTA-assay and the bead assay. Firstly, the former two assays are inhibited in the presence of iron free ligands (Aydinok et al. 2012 Haematologica; Walter et
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30

González-Vallejo, Elena B., Anunciación Abadía, Jose Antonio González-Reyes, et al. "Reduction of ferric chelates by leaf plasma membrane preparations from Fe-deficient and Fe-sufficient sugar beet." Functional Plant Biology 26, no. 6 (1999): 601. http://dx.doi.org/10.1071/pp99002.

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The ferric chelate reductase activities of leaf plasma membranes isolated from the leaves of Fe-deficient and Fe-sufficient sugar beet have been characterized. Substrates used were the complexes of ferric iron with ethylene diamine tetraacetic acid, citric acid and malic acid. Iron deficiency was associated with 1.5- to 2-fold increases in leaf plasma membrane ferric chelate reductase activity when rates were calculated on a protein basis. The natural complexes of ferric iron with citrate and especially with malate were good substrates for the ferric chelate reductase enzyme present in leaf pl
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31

Mohammadnia, Saber, Maryam Haghighi, Maryam Mozafarian, and András Geösel. "Impact of Mycorrhiza Inoculations and Iron Amino Chelate on Growth and Physiological Changes of Cucumber Seedlings Across Different pH Levels." Plants 14, no. 3 (2025): 341. https://doi.org/10.3390/plants14030341.

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Cucumber, a vital greenhouse crop, thrives in soils with a pH range of 5.5–6.5, yet the combined effects of arbuscular mycorrhizal fungi (AMF) and iron amino chelates on its growth and physiological responses across varying pH levels remain underexplored. This study used a factorial design in a completely randomized setup with three replications and was conducted at the Horticulture Department of Isfahan University of Technology. The aim of this study was to investigate the effects of AMF inoculation (Glomus mosseae) and iron amino chelates on the growth and physiological responses of cucumber
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32

Lomozová, Zuzana, Václav Tvrdý, Marcel Hrubša, et al. "Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo." Antioxidants 10, no. 5 (2021): 679. http://dx.doi.org/10.3390/antiox10050679.

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2,3-Dehydrosilybin (DHS) was previously shown to chelate and reduce both copper and iron ions. In this study, similar experiments with 2,3-dehydrosilychristin (DHSCH) showed that this congener of DHS also chelates and reduces both metals. Statistical analysis pointed to some differences between both compounds: in general, DHS appeared to be a more potent iron and copper chelator, and a copper reducing agent under acidic conditions, while DHSCH was a more potent copper reducing agent under neutral conditions. In the next step, both DHS and DHSCH were tested for metal-based Fenton chemistry in v
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33

Albano, Joseph P., and William B. Miller. "Iron Chelate Photodegradation in Fertilizer Solution Affects Foliar Iron and Manganese." HortScience 32, no. 3 (1997): 445A—445. http://dx.doi.org/10.21273/hortsci.32.3.445a.

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We have shown previously that Fe-chelates incorporated into soluble fertilizers are vulnerable to photodegradation, and that such solutions can cause modifications in root reductase activity. The objective of this research was to determine the effects of Fe-chelate photodegradation under commercial production conditions. Marigolds were grown in a greenhouse and transplanted stepwise from #200 plug trays to 804 packs to 11.4-cm (4.5-inch) pots. Plants were harvested at the end of each stage, and treatments consisted of either irradiated (complete loss of soluble Fe) or non-irradiated fertilizer
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34

Hershkowitz, Julie A., Mackenzie G. Dey, Royal Heins, and Bruce Bugbee. "Fertigation with Fe-EDTA, Fe-DTPA, and Fe-EDDHA Chelates to Prevent Iron Chlorosis of Sensitive Species in High-pH Soilless Media." HortScience 60, no. 3 (2025): 404–10. https://doi.org/10.21273/hortsci17892-24.

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Multiple studies have examined the use of chelates to correct pH-induced Fe chlorosis. Here we report the effects of three common chelates on prevention of Fe chlorosis in two sensitive species at high pH. Calibrachoa and soybean were grown in three media pH ranges (6.0 to 6.5, 7.0 to 7.2, and 7.6 to 7.8) and supplied with 1 mg·L−1 Fe as Fe-EDTA, Fe-DTPA, or Fe-EDDHA through fertigation. Chelate effectiveness was quantified by chlorosis rating and dry mass. In Calibrachoa, all three chelates prevented chlorosis at media pH up to 6.5, but above pH 7.2 only Fe-EDDHA was effective. Dry mass decre
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35

Ogura, Jiro, Toshihiro Sato, Kei Higuchi, et al. "Binding of Citrate-Fe3+ to Plastic Culture Dishes, an Artefact Useful as a Simple Technique to Screen for New Iron Chelators." International Journal of Molecular Sciences 23, no. 12 (2022): 6657. http://dx.doi.org/10.3390/ijms23126657.

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NaCT mediates citrate uptake in the liver cell line HepG2. When these cells were exposed to iron (Fe3+), citrate uptake/binding as monitored by the association of [14C]-citrate with cells increased. However, there was no change in NaCT expression and function, indicating that NaCT was not responsible for this Fe3+-induced citrate uptake/binding. Interestingly however, the process exhibited substrate selectivity and saturability as if the process was mediated by a transporter. Notwithstanding these features, subsequent studies demonstrated that the iron-induced citrate uptake/binding did not in
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36

Oses-Pedraza, Rómulo, Estefanía Bonnail, Paris Lavin, et al. "Fenton-Mediated Chlorophenol Degradation by Iron-Reducing Compounds Isolated from Endophytic Fungi in Atacama Puna Plateau Lecanicillium ATA01." Fermentation 8, no. 4 (2022): 147. http://dx.doi.org/10.3390/fermentation8040147.

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Low-molecular-mass iron-reducing compounds (IRCs) were produced by entomopathogenic endophytic fungi Lecanicillium sp. ATA01 in liquid cultures. The extracellular hydrophilic extract contained three IRCs formed by peptides, iron and phenolate structures with molecular masses of 1207, 567 and 550 Da. These compounds were able to chelate and mediate the reduction of Fe+3 to Fe+2 and oxidized recalcitrant lignin-model substrates such as veratryl alcohol (VA), 2,6-dimethoxyphenol (DMP), and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) with or without hydrogen peroxide. Besides, I
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37

Arvid, Jensen, Smith Marianne, Saadani Ali, and Hassan Hagagy Rahma. "The Efficacy of Duosomic® Iron over Standard Iron Formulations in IDA Management: A Randomized Controlled Comparative Clinical Study." Sarcouncil Journal of Applied Sciences 4, no. 10 (2024): 1–9. https://doi.org/10.5281/zenodo.13921419.

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<strong>Background:</strong> Iron deficiency anemia (IDA) is a common condition worldwide, and oral iron therapies have varied efficacy and safety profiles. This study aims to evaluate the comparative efficacy and safety of DUOSOMIC<sup>&reg;</sup> Iron, Iron Sucrose Ester, and Ferrous Bisglycinate Chelate in correcting anemia, replenishing iron stores, and enhancing erythropoiesis. <strong>Methods:</strong> This paper shows results from three clinical studies: a randomized controlled trial study on DUOSOMIC<sup>&reg;</sup> Iron, an Iron Sucrose Ester, and a Ferrous Bisglycinate Chelate. A tot
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38

Klem-Marciniak, Ewelina, Marta Huculak-Mączka, Kinga Marecka, Krystyna Hoffmann, and Józef Hoffmann. "Chemical Stability of the Fertilizer Chelates Fe-EDDHA and Fe-EDDHSA over Time." Molecules 26, no. 7 (2021): 1933. http://dx.doi.org/10.3390/molecules26071933.

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In application conditions, the influence of environmental parameters on used fertilizer chelates and their distribution over time is important. For this purpose, the changes in the content of micronutrient ions and Fe-EDDHA and Fe-EDDHSA chelates in an aqueous medium at different pH values were studied. In the assumed time, changes in the ions content were analyzed using the voltammetry method at pH 3, 5 and 7. The content of isomers and chelate forms was analyzed by ion pair chromatography at pH 3, 5 and 7. These studies allowed us to determine the effect of pH on the stability of iron chelat
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39

Kaman, Singh. "Studies on iron-sucrose chelate formation and development of brown colour." Journal of Indian Chemical Society Vol. 76, Apr 1999 (1999): 231–32. https://doi.org/10.5281/zenodo.5848593.

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Department of Chemistry, Government P. G. College, Tikamgarh-472 001, India <em>Manuscript received 19 March 1997, revised 8 October 1998, accepted 7 December 1998</em> Formation and isolation of iron-sucrose chelate with respect to caramelization has been investigated together with the reappraisal of spectral and analytical evidences for chelate formation. The chelate was found to have salty taste but with no metallic taste. Its dark brown aqueous solution has salty, slight caramel taste but again with no metallic taste. The study suggests that the deterioration of sucrose crystal does not se
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40

Manulis, Shulamit, David Netzer, and Isaac Barash. "Acquisition of iron by Stemphylium botryosum under iron-replete conditions." Canadian Journal of Microbiology 33, no. 8 (1987): 652–57. http://dx.doi.org/10.1139/m87-114.

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The assimilation of iron by Stemphylium botryosum under iron-replete conditions involved mainly three steps: (i) binding of iron to the cell surface, (ii) reduction of Fe3+ into Fe2+, and (iii) transport of the ferrous iron across the cell membrane. However, the possibility that the fungus is capable of transporting ferric iron also has not been excluded. Adsorption was responsible for up to 75% of the iron accumulated by the cells. Mycelial cells exhibited a high capacity for Fe3+ reduction. Approximately 70% of the reductive activity was assigned to cell surface bound reducing compounds whic
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41

Soumya, B., K. P. Vani, and K. Surekha. "Effect of Iron Nutrition on Growth and Productivity of Aerobic Rice (Oryza sativa)." International Journal of Bio-resource and Stress Management 13, Dec, 12 (2022): 1403–10. http://dx.doi.org/10.23910/1.2022.3276.

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A field experiment was conducted during kharif seasons (June–October) of 2012 and 2013 at College Farm, College of Agriculture, Professor Jayashankar Telangana State Agricultural University, Hyderabad, Telengana, India to evaluate the response of rice cultivars and iron nutrition on growth and yield of aerobic rice. Experiment comprising of three rice cultivars (Tellahamsa, MTU 1010 and KRH 2) and twelve sources and modes of iron nutrition i.e. control (no iron), basal application of iron sulphate @ 25 kg ha-1, basal application of Iron chelate @ 25 kg ha-1, 3 foliar sprays of 2% iron sulphate
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42

Evcan, Ezgi, and Sukru Gulec. "The development of lentil derived protein–iron complexes and their effects on iron deficiency anemia in vitro." Food & Function 11, no. 5 (2020): 4185–92. http://dx.doi.org/10.1039/d0fo00384k.

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Lentil derived proteins have the capacity to chelate iron minerals and hydrolysed protein–iron complexes have functional properties on iron deficiency anemia in in vitro by influencing mRNA levels of iron regulating genes.
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43

Sato, Hideaki, Masakazu Sugishima, Hiroshi Sakamoto, et al. "Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem: presence of a hydrogen-bond network on the distal side." Biochemical Journal 419, no. 2 (2009): 339–45. http://dx.doi.org/10.1042/bj20082279.

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HO (haem oxygenase) catalyses the degradation of haem to biliverdin, CO and ferrous iron via three successive oxygenation reactions, i.e. haem to α-hydroxyhaem, α-hydroxyhaem to α-verdohaem and α-verdohaem to ferric biliverdin–iron chelate. In the present study, we determined the crystal structure of ferrous α-verdohaem–rat HO-1 complex at 2.2 Å (1 Å=0.1 nm) resolution. The overall structure of the verdohaem complex was similar to that of the haem complex. Water or OH− was co-ordinated to the verdohaem iron as a distal ligand. A hydrogen-bond network consisting of water molecules and several a
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44

Sabir, Ali. "Pre-grafting treatments of plant fatty acid extract, seaweed (Ascophylum nodosum L.) and micronized calcite increase the grafting success in grapevine propagation." Agriculture and Food Sciences Research 11, no. 2 (2024): 222–27. https://doi.org/10.20448/aesr.v11i2.6254.

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Globally increasing interest in environmentally sound viticulture in precision agriculture promoted the viticulturists to find eco-friendly treatments in both vineyards and nurseries. The present study was conducted to evaluate the possible effects of plant oil extract (as plant activator), seaweed (Ascophylum nodosum L.) extract, calcium oxide and iron chelate on callusing degree on graft union point and final take of ‘Trakya Ilkeren’ table grape cultivar grafted on 110 Richter (Berlandieri x Rupestris) rootstock. Bud break and shoot emergence commenced earlier in grafts subjected to pre-graf
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45

Soumya, B., K. Surekha, and Kada Siddappa. "Evaluating the Impact of Genetic Diversity and Iron Fertilization Methods on Iron Bioavailability in Aerobic Rice Cultivation System." Agriculture Association of Textile Chemical and Critical Reviews 13, no. 1 (2025): 518–22. https://doi.org/10.21276/aatccreview.2025.13.01.517.

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Iron deficiency is a significant constraint to rice production, particularly in aerobic systems. A two-year field experiment was conducted at Professor Jayashankar Telangana State Agricultural University, Hyderabad, India to evaluate the iron uptake of three aerobic rice cultivars (M1, M2, and M3) under twelve different iron fertilization strategies in sandy clay loam soil. The experiment laid out in a split-plot design, examined the efficacy of iron sulphate and iron chelate applied through foliar and soil applications, as well as their combinations. Iron content and uptake were measured at v
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46

Olakanmi, O., J. B. Stokes, and B. E. Britigan. "Acquisition of iron bound to low molecular weight chelates by human monocyte-derived macrophages." Journal of Immunology 153, no. 6 (1994): 2691–703. http://dx.doi.org/10.4049/jimmunol.153.6.2691.

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Abstract The iron content of tissue macrophages increases under conditions of elevated extracellular iron. Studies of macrophage iron acquisition have generally focused on iron uptake from transferrin via receptor-mediated endocytosis. However, in vivo macrophages are also exposed to extracellular low m.w. iron chelates, particularly under conditions of iron overload. Therefore, we examined the mechanism of iron acquisition from low m.w. chelates by human monocyte-derived macrophages. Iron acquisition was influenced by the nature of the iron chelate: Fe-ascorbate &amp;gt; Fe-citrate &amp;gt; F
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47

Selyutina, Olga Yu, Polina A. Kononova, Vladimir E. Koshman, Lidiya G. Fedenok, and Nikolay E. Polyakov. "The Interplay of Ascorbic Acid with Quinones-Chelators—Influence on Lipid Peroxidation: Insight into Anticancer Activity." Antioxidants 11, no. 2 (2022): 376. http://dx.doi.org/10.3390/antiox11020376.

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Ascorbic acid is a multifaceted compound that can perform both antioxidant and pro-oxidant activities in the redox reactions induced by transition metal ions, so its role in nature and especially in the human body is still the subject of debate. In the present study, we have examined the influence of ascorbic acid on lipid peroxidation in a model system that mimics the cell membrane, namely micelles of linoleic acid (LA), induced by chelate complexes of iron and copper ions with quinone-chelator 2-phenyl-4-(butylamino)-naphtholquinoline-7,12-dione (Q1). This quinone effectively generates react
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48

Bachman, G. R., and W. B. Miller. "Iron chelate inducible iron/manganese toxicity in zonal geranium." Journal of Plant Nutrition 18, no. 9 (1995): 1917–29. http://dx.doi.org/10.1080/01904169509365033.

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49

Crichton, Robert R., Roberta J. Ward, and Robert C. Hider. "The Efficacy of Iron Chelators for Removing Iron from Specific Brain Regions and the Pituitary—Ironing out the Brain." Pharmaceuticals 12, no. 3 (2019): 138. http://dx.doi.org/10.3390/ph12030138.

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Iron chelation therapy, either subcutaneous or orally administered, has been used successfully in various clinical conditions. The removal of excess iron from various tissues, e.g., the liver spleen, heart, and the pituitary, in beta thalassemia patients, has become an essential therapy to prolong life. More recently, the use of deferiprone to chelate iron from various brain regions in Parkinson’s Disease and Friederich’s Ataxia has yielded encouraging results, although the side effects, in &lt;2% of Parkinson’s Disease(PD) patients, have limited its long-term use. A new class of hydroxpyridin
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50

Timoshnikov, Viktor A., Tatyana V. Kobzeva, Nikolay E. Polyakov, and George J. Kontoghiorghes. "Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone." International Journal of Molecular Sciences 21, no. 11 (2020): 3967. http://dx.doi.org/10.3390/ijms21113967.

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Ascorbic acid (AscH2) is one of the most important vitamins found in the human diet, with many biological functions including antioxidant, chelating, and coenzyme activities. Ascorbic acid is also widely used in medical practice especially for increasing iron absorption and as an adjuvant therapeutic in iron chelation therapy, but its mode of action and implications in iron metabolism and toxicity are not yet clear. In this study, we used UV–Vis spectrophotometry, NMR spectroscopy, and EPR spin trapping spectroscopy to investigate the antioxidant/pro-oxidant effects of ascorbic acid in reactio
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