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Academic literature on the topic 'ISC assembly machinery'

Author: Grafiati

Published: 10 March 2023

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Journal articles on the topic "ISC assembly machinery"

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Vilella, Felipe, Rui Alves, María Teresa Rodríguez-Manzaneque, et al. "Evolution and Cellular Function of Monothiol Glutaredoxins: Involvement in Iron-Sulphur Cluster Assembly." Comparative and Functional Genomics 5, no. 4 (2004): 328–41. http://dx.doi.org/10.1002/cfg.406.

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A number of bacterial species, mostly proteobacteria, possess monothiol glutaredoxins homologous to theSaccharomyces cerevisiaemitochondrial protein Grx5, which is involved in iron–sulphur cluster synthesis. Phylogenetic profiling is used to predict that bacterial monothiol glutaredoxins also participate in the iron–sulphur cluster (ISC) assembly machinery, because their phylogenetic profiles are similar to the profiles of the bacterial homologues of yeast ISC proteins. High evolutionary co-occurrence is observed between the Grx5 homologues and the homologues of the Yah1 ferredoxin, the scaffo

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Camponeschi, Francesca, Simone Ciofi-Baffoni, Vito Calderone, and Lucia Banci. "Molecular Basis of Rare Diseases Associated to the Maturation of Mitochondrial [4Fe-4S]-Containing Proteins." Biomolecules 12, no. 7 (2022): 1009. http://dx.doi.org/10.3390/biom12071009.

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The importance of mitochondria in mammalian cells is widely known. Several biochemical reactions and pathways take place within mitochondria: among them, there are those involving the biogenesis of the iron–sulfur (Fe-S) clusters. The latter are evolutionarily conserved, ubiquitous inorganic cofactors, performing a variety of functions, such as electron transport, enzymatic catalysis, DNA maintenance, and gene expression regulation. The synthesis and distribution of Fe-S clusters are strictly controlled cellular processes that involve several mitochondrial proteins that specifically interact e

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Wang, Jian, Carine Fillebeen, Guohua Chen, Annette Biederbick, Roland Lill, and Kostas Pantopoulos. "Iron-Dependent Degradation of Apo-IRP1 by the Ubiquitin-Proteasome Pathway." Molecular and Cellular Biology 27, no. 7 (2007): 2423–30. http://dx.doi.org/10.1128/mcb.01111-06.

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ABSTRACT Iron regulatory protein 1 (IRP1) controls the translation or stability of several mRNAs by binding to “iron-responsive elements” within their untranslated regions. In iron-replete cells, IRP1 assembles a cubane iron-sulfur cluster (ISC) that inhibits RNA-binding activity and converts the protein to cytosolic aconitase. We show that the constitutive IRP1C437S mutant, which fails to form an ISC, is destabilized by iron. Thus, exposure of H1299 cells to ferric ammonium citrate reduced the half-life of transfected IRP1C437S from ∼24 h to ∼10 h. The iron-dependent degradation of IRP1C437S

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Böttinger, Lena, Christoph U. Mårtensson, Jiyao Song, Nicole Zufall, Nils Wiedemann, and Thomas Becker. "Respiratory chain supercomplexes associate with the cysteine desulfurase complex of the iron–sulfur cluster assembly machinery." Molecular Biology of the Cell 29, no. 7 (2018): 776–85. http://dx.doi.org/10.1091/mbc.e17-09-0555.

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Mitochondria are the powerhouses of eukaryotic cells. The activity of the respiratory chain complexes generates a proton gradient across the inner membrane, which is used by the F1FO-ATP synthase to produce ATP for cellular metabolism. In baker’s yeast, Saccharomyces cerevisiae, the cytochrome bc1 complex (complex III) and cytochrome c oxidase (complex IV) associate in respiratory chain supercomplexes. Iron–sulfur clusters (ISC) form reactive centers of respiratory chain complexes. The assembly of ISC occurs in the mitochondrial matrix and is essential for cell viability. The cysteine desulfur

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Martens, Eric C., Joseph Gawronski-Salerno, Danielle L. Vokal, Molly C. Pellitteri, Megan L. Menard, and Heidi Goodrich-Blair. "Xenorhabdus nematophila Requires an Intact iscRSUA-hscBA-fdx Operon To Colonize Steinernema carpocapsae Nematodes." Journal of Bacteriology 185, no. 12 (2003): 3678–82. http://dx.doi.org/10.1128/jb.185.12.3678-3682.2003.

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ABSTRACT An insertion between iscA and hscB of the Xenorhabdus nematophila iscRSUA-hscBA-fdx locus, predicted to encode Fe-S assembly machinery, prevented colonization of Steinernema carpocapsae nematodes. The insertion disrupted cotranscription of iscA and hscB, but did not reduce hscBA expression, suggesting that X. nematophila requires coordinated expression of the isc-hsc-fdx locus for colonization.

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Sheftel, Alex D., Claudia Wilbrecht, Oliver Stehling, et al. "The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation." Molecular Biology of the Cell 23, no. 7 (2012): 1157–66. http://dx.doi.org/10.1091/mbc.e11-09-0772.

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Members of the bacterial and mitochondrial iron–sulfur cluster (ISC) assembly machinery include the so-called A-type ISC proteins, which support the assembly of a subset of Fe/S apoproteins. The human genome encodes two A-type proteins, termed ISCA1 and ISCA2, which are related to Saccharomyces cerevisiae Isa1 and Isa2, respectively. An additional protein, Iba57, physically interacts with Isa1 and Isa2 in yeast. To test the cellular role of human ISCA1, ISCA2, and IBA57, HeLa cells were depleted for any of these proteins by RNA interference technology. Depleted cells contained massively swolle

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Gomez-Casati, Diego F., Maria V. Busi, Julieta Barchiesi, Maria A. Pagani, Noelia S. Marchetti-Acosta, and Agustina Terenzi. "Fe-S Protein Synthesis in Green Algae Mitochondria." Plants 10, no. 2 (2021): 200. http://dx.doi.org/10.3390/plants10020200.

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Iron and sulfur are two essential elements for all organisms. These elements form the Fe-S clusters that are present as cofactors in numerous proteins and protein complexes related to key processes in cells, such as respiration and photosynthesis, and participate in numerous enzymatic reactions. In photosynthetic organisms, the ISC and SUF Fe-S cluster synthesis pathways are located in organelles, mitochondria, and chloroplasts, respectively. There is also a third biosynthetic machinery in the cytosol (CIA) that is dependent on the mitochondria for its function. The genes and proteins that par

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Lill, Roland, and Sven-A. Freibert. "Mechanisms of Mitochondrial Iron-Sulfur Protein Biogenesis." Annual Review of Biochemistry 89, no. 1 (2020): 471–99. http://dx.doi.org/10.1146/annurev-biochem-013118-111540.

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Mitochondria are essential in most eukaryotes and are involved in numerous biological functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and steroid metabolism. Work over the past two decades has uncovered the biogenesis of cellular iron-sulfur (Fe/S) proteins as the essential and minimal function of mitochondria. This process is catalyzed by the bacteria-derived iron-sulfur cluster assembly (ISC) machinery and has been dissected into three major steps: de novo synthesis of a [2Fe-2S] cluster on a scaffold protein; Hsp70 chaperone–mediated trafficking of the

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Bandyopadhyay, Sibali, Kala Chandramouli, and Michael K. Johnson. "Iron–sulfur cluster biosynthesis." Biochemical Society Transactions 36, no. 6 (2008): 1112–19. http://dx.doi.org/10.1042/bst0361112.

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Iron–sulfur (Fe–S) clusters are present in more than 200 different types of enzymes or proteins and constitute one of the most ancient, ubiquitous and structurally diverse classes of biological prosthetic groups. Hence the process of Fe–S cluster biosynthesis is essential to almost all forms of life and is remarkably conserved in prokaryotic and eukaryotic organisms. Three distinct types of Fe–S cluster assembly machinery have been established in bacteria, termed the NIF, ISC and SUF systems, and, in each case, the overall mechanism involves cysteine desulfurase-mediated assembly of transient

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Uzarska, Marta A., Rafal Dutkiewicz, Sven-Andreas Freibert, Roland Lill, and Ulrich Mühlenhoff. "The mitochondrial Hsp70 chaperone Ssq1 facilitates Fe/S cluster transfer from Isu1 to Grx5 by complex formation." Molecular Biology of the Cell 24, no. 12 (2013): 1830–41. http://dx.doi.org/10.1091/mbc.e12-09-0644.

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The mitochondrial Hsp70 chaperone Ssq1 plays a dedicated role in the maturation of iron–sulfur (Fe/S) proteins, an essential process of mitochondria. Similar to its bacterial orthologue HscA, Ssq1 binds to the scaffold protein Isu1, thereby facilitating dissociation of the newly synthesized Fe/S cluster on Isu1 and its transfer to target apoproteins. Here we use in vivo and in vitro approaches to show that Ssq1 also interacts with the monothiol glutaredoxin 5 (Grx5) at a binding site different from that of Isu1. Grx5 binding does not stimulate the ATPase activity of Ssq1 and is most pronounced

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Dissertations / Theses on the topic "ISC assembly machinery"

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Adams, Azeez Olawale. "Control of reconfigurable assembly system." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5368.

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Thesis (MScEng (Mechanical and Mechatronic Engineering))--University of Stellenbosch, 2010.<br>ENGLISH ABSTRACT: This work considers the control of reconfigurable assembly systems using a welding assembly system as a case study. The assembly system consists of a pallet magazine, a feeding system, an inspection and removal system, a welding system and a conveyor. The aim of the work is to compare PC and PLC as controllers, as well as to compare two different approaches to reconfigurable control. The control system of the pallet magazine was developed using a PC and a PLC. The PC control w

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Křoustek, Jakub. "Rekonfigurovatelná analýza strojového kódu." Doctoral thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2015. http://www.nusl.cz/ntk/nusl-261276.

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Analýza softwaru je metodologie, jejímž účelem je analyzovat chování daného programu. Jednotlivé metody této analýzy je možné využít i v dalších oborech, jako je zpětné inženýrství, migrace kódu apod. V této práci se zaměříme na analýzu strojového kódu, na zjištění nedostatků existujících metod a na návrh metod nových, které umožní rychlou a přesnou rekonfigurovatelnou analýzu kódu (tj. budou nezávislé na konkrétní cílové platformě). Zkoumány budou dva typy analýz - dynamická (tj. analýza za běhu aplikace) a statická (tj. analýza aplikace bez jejího spuštění). Přínos této práce v rámci dynamic

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Saudino, Giovanni. "Protein expression and characterization for systems involved in the biogenesis of iron sulfur proteins." Doctoral thesis, 2021. http://hdl.handle.net/2158/1251249.

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Iron-sulfur clusters are essential cofactors found in all kingdoms of life; they had unique functional roles throughout evolution. These clusters, which are the second major form of complex iron cofactors in biology, are ubiquitous in all organisms, playing a key role in several biological pathways. Mutations on the protein involved in the iron-sulfur clusters biosynthesis pathway are associated with a group of multiple mitochondrial dysfunction syndromes (MMDS). These severe diseases could give infantile encephalopathy, lactic acidosis, leukodystrophy and death in early childhood. In human ce

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Books on the topic "ISC assembly machinery"

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Ovtov, Vladimir. Machine parts. Course design. INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/1171976.

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The textbook discusses the methodology of course design of general-purpose drives with a single-stage gearbox (cylindrical, conical and worm) and a V-belt or chain transmission. The procedure for calculating gears and constructing assembly drawings of gearboxes is shown, the development of specifications using the COMPASS-3D computer-aided design system is described. Examples of the design of drawings of the general type of the drive, assembly drawings of gearboxes and working drawings of parts of various types of gearboxes are given. Meets the requirements of the federal state education

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Strebkov, Sergey, and Andrey Sahnov. Machine repair technology. INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/1184662.

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The tutorial discusses the technological processes of remontamashin, contains elements of the design of technological processes for the restoration of parts and assembly units, describes ways to restore the main defects of machine parts. Meets the requirements of the federal state educational standards of higher education of the latest generation. It is intended for students in the direction of training 35.03.06 "Agroengineering".

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Ivanov, Anatoliy. Flexible modular assembly lines on a single structural basis. INFRA-M Academic Publishing LLC., 2022. http://dx.doi.org/10.12737/1196558.

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The textbook discusses topical issues of automating the assembly of an extensive range of machine and instrument-making products based on highly efficient robotic reconfigurable systems of a new generation built on a single structural basis. The possibility of fast organization of automated assembly of new types of products, which is provided by the presence of a flexible basic set as part of the complex (line), is shown. A complete set of original technical means for basic and service operations of assembly and control of products is described. Analytical conditions of automatic assembly are

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Yurenkova, Lyubov', Viktor Burlay, Vladimir Fedorenko, and Aleksey Andreev. Engineering graphics: Atlas of assembly units with different types of connections of parts. INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/953403.

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The tutorial contains drawings of assembly units with a description of their design. Special attention is paid to the analysis of the connections of the parts. Examples of assembly units containing a small number of parts are used to describe the most common types of connections in the designs of machines and devices out of several dozen currently known. The atlas will allow you to introduce students to various modern types of connections of parts in a short time during classes. Meets the requirements of the federal state educational standards of higher education of the latest generation. For

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Moses, Matthew S., and Gregory S. Chirikjian. Reproduction. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0007.

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Computing pioneer and polymath John von Neumann introduced the concept of a Universal Constructor as part of his effort to develop a mathematical theory describing living organisms. A Universal Constructor is a kinematic machine able to manipulate and assemble primitive building blocks. Von Neumann showed how this hypothetical constructor, being itself composed of the same primitive blocks, could self-reproduce and evolve. Remarkably, although this model system pre-dates the discovery of the genetic code, it applies to cell molecular biology as well as man-made machines. This chapter describes

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International, IPC. IPC-HERMES-9852, Version 1.5 the Global Standard for Machine-To-Machine Communication in SMT Assembly. IPC International, 2022.

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Prescott, Tony J., Nathan Lepora, and Paul F. M. J. Verschure, eds. Living machines. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.001.0001.

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Biomimetics is the development of novel technologies through the distillation of ideas from the study of biological systems. Biohybrids are formed through the combination of at least one biological component—an existing living system—and at least one artificial, newly engineered component. These two fields are united under the theme of Living Machines—the idea that we can construct artifacts that not only mimic life but also build on the same fundamental principles. The research described in this volume seeks to understand and emulate life’s ability to self-organize, metabolize, grow, and repr

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Fukuda, Toshio, Masahiro Nakajima, Masaru Takeuchi, and Yasuhisa Hasegawa. Micro- and nanotechnology for living machines. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0052.

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The chapter Micro- and nanotechnology for living machines describes research on new biohybrid technologies, engineered at the micro- and nano-scales, that combine some of the benefits of mechanical and electronic systems with those of biological systems. The chapter begins by reviewing some of the challenges of building devices at very small physical scales and discusses how new fabrication methodologies could impact on different classes of industrial, daily life, and biomedical products. We next explain how progress is being achieved through advances in micro- and nanomechatronics, particular

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Anderson, James A. Software. Oxford University Press, 2018. http://dx.doi.org/10.1093/acprof:oso/9780199357789.003.0004.

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Digital computers are “protean” in that they can become almost anything through software. Their basic design elements came from a 19th-century British tradition in logic, exemplified by Boole and Babbage. It seemed natural to have logic realized in hardware. This tradition culminated in the work of Alan Turing who proposed a universal computing machine, now called a Turing machine, based on logic. Although hardware that computes logic functions lies at the core of digital hardware, low-level practical machine operations are grouped together in “words.” Programs are based on hardware operations

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Little, Max A. Machine Learning for Signal Processing. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198714934.001.0001.

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Digital signal processing (DSP) is one of the ‘foundational’ engineering topics of the modern world, without which technologies such the mobile phone, television, CD and MP3 players, WiFi and radar, would not be possible. A relative newcomer by comparison, statistical machine learning is the theoretical backbone of exciting technologies such as automatic techniques for car registration plate recognition, speech recognition, stock market prediction, defect detection on assembly lines, robot guidance and autonomous car navigation. Statistical machine learning exploits the analogy between intelli

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Book chapters on the topic "ISC assembly machinery"

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Gilder, Jules H. "Machine Code or Assembly Language." In Apple IIc and IIe Assembly Language. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-6424-5_1.

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Gilder, Jules H. "A Poke at Machine Code." In Apple IIc and IIe Assembly Language. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-6424-5_6.

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Conference papers on the topic "ISC assembly machinery"

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Wang, Mu-Chun, Zhen-Ying Hsieh, Kuo-Shu Huang, Shuang-Yuan Chen, and Heng-Sheng Huang. "Investigation of Dicing Saw Methods Impacting Back-End Assembly Process." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70015.

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The chip size, substrate material and package type of ICs are continuously changed due to the advanced process development. In order to satisfy these needs, it is necessary to cut wafers as discrete chip shape. Recently, the cutting technology cardinally relies on the thinner diamond blade plus some variable dicing saw parameters to obtain the separate chips. Although the cutting process is similar to that with traditional mechanical cutting, the accuracy and the quality are totally different. The previous is better than the last. Therefore, the cutting cost is not easily reduced more, except

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Malinin, Grigoriy, and S. Yankevich. "LOGIC AUTOMATIC DRIVER CONTROL IN THE SYSTEM OF CONTROL OF POWERFUL POWER CONVERTERS." In CAD/EDA/SIMULATION IN MODERN ELECTRONICS 2019. Bryansk State Technical University, 2019. http://dx.doi.org/10.30987/conferencearticle_5e02821252ea43.36490574.

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The paper presents an analysis of possible emergency conditions in a voltage converter controlled from an FPGA or a microcontroller and a method for eliminating them using a logical machine. The principle of operation of the machine is explained using a model assembled in CAD Xilinx ISE Design Suite.

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Wang, Mu-Chun, Kuo-Shu Huang, Zhen-Ying Hsieh, Shuang-Yuan Chen, and Heng-Sheng Huang. "Avoidance of Bonding Pad Contamination Affecting Back-End Assembly Process." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70016.

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While the process fabrication and the electronic applications develop quickly, the die size and the package type also confront the improvement from the customers’ request to achieve the better signal performance in IC products. In cost consideration and marketing competition, most of commercial IC products still adopt the wire-bond technology, except some high performance products with solder/gold balls adhesion process. For consumer ICs, the gold wire is the major material to connect the IC chip and the lead frame through the bondability technology. In the recent era, the bond pad size and pi

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Robeda, James, and Richard Morgan. "Evaluation of Machine-Vision Based Profile Measurements for Rolling Railcar Wheels." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-61890.

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In an effort to increase the number of wheels with measured profile parameters and reduce the number of condemnable wheels in service, machine vision-based wayside inspection systems are being developed to “virtually” gage all wheels of passing trains. In 2003, Transportation Technology Center, Inc. (TTCI), a wholly owned subsidiary of the Association of American Railroads (AAR), evaluated a pair of these wheel profile monitoring systems from two different vendors. Wheel-related expenses (inspection, maintenance, and replacement) make up about 37 percent of annual car maintenance costs. A sign

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Bourret, Quentin, Pierre-Olivier Lemieux, Julie Charland, and Rachid Aissaoui. "Grasp Planning Of Unknown Object For Digital Human Model." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001908.

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ObjectiveGrasp planning is a popular topic in the fields of robotic and Digital Human Model (DHM) (4, 6, 7, 9, 10, 11). So far, the proposed planners do not consider the final posture of the DHM has a criteria when determining potential grasps. In (4), a grasping algorithm has been developed to automatically grasp known tools. The present work introduces a grasp planner for single-hand grasp on an unknown object, further referred as “part”.MethodThe grasp planner gives has a result a grasp pose (position + orientation) for the posture solver (Smart Posturing Engine) to reach. The input necessa

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Reports on the topic "ISC assembly machinery"

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Alonso-Robisco, Andrés, José Manuel Carbó, and José Manuel Carbó. Machine Learning methods in climate finance: a systematic review. Banco de España, 2023. http://dx.doi.org/10.53479/29594.

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Preventing the materialization of climate change is one of the main challenges of our time. The involvement of the financial sector is a fundamental pillar in this task, which has led to the emergence of a new field in the literature, climate finance. In turn, the use of Machine Learning (ML) as a tool to analyze climate finance is on the rise, due to the need to use big data to collect new climate-related information and model complex non-linear relationships. Considering the proliferation of articles in this field, and the potential for the use of ML, we propose a review of the academic lite

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Wilson, Thomas E., Avraham A. Levy, and Tzvi Tzfira. Controlling Early Stages of DNA Repair for Gene-targeting Enhancement in Plants. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7697124.bard.

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Gene targeting (GT) is a much needed technology as a tool for plant research and for the precise engineering of crop species. Recent advances in this field have shown that the presence of a DNA double-strand break (DSB) in a genomic locus is critical for the integration of an exogenous DNA molecule introduced into this locus. This integration can occur via either non-homologous end joining (NHEJ) into the break or homologous recombination (HR) between the broken genomic DNA and the introduced vector. A bottleneck for DNA integration via HR is the machinery responsible for homology search and s

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Stern, David B., and Gadi Schuster. Manipulation of Gene Expression in the Chloroplast: Control of mRNA Stability and Transcription Termination. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568750.bard.

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Chloroplasts are the site of photosynthesis and of other essential biosynthetic activities in plant cells. Chloroplasts are semi-autonomous organelles, since they contain their own genomes and protein biosynthetic machinery, but depend on the coordinate expression of nuclear genes to assemble macromolecular complexes. The bioeingineering of plants requires manipulation of chloroplast gene expression, and thus a knowledge of the molecular mechanisms that modulate mRNA and protein production. In this proposal the heterotrophic green alga Chlamydomonas reinhardtii has been used as a model system

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Patel, Yusef. File to Factory: A case study of automated prefabrication house-building methods for small-to-medium enterprises. Unitec ePress, 2017. http://dx.doi.org/10.34074/ocds.0823.

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The Eco-Digital Fabrication (EDFAB) research project aimed to investigate how automated prefabrication technologies and off-the-shelf construction products can be employed to disrupt building industry norms. The aim of this research – conducted at the University of Auckland and Unitec Institute of Technology from 2014 onward – was to provide small-to-medium enterprises in the construction industry with a pathway to upskill and increase construction productivity through the use of these processes. The availability of automated machines and easy-to-use fabrication software is increasing dramatic

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Bar-Joseph, Moshe, William O. Dawson, and Munir Mawassi. Role of Defective RNAs in Citrus Tristeza Virus Diseases. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7575279.bard.

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This program focused on citrus tristeza virus (CTV), the largest and one of the most complex RNA-plant-viruses. The economic importance of this virus to the US and Israeli citrus industries, its uniqueness among RNA viruses and the possibility to tame the virus and eventually turn it into a useful tool for the protection and genetic improvement of citrus trees justify these continued efforts. Although the overall goal of this project was to study the role(s) of CTV associated defective (d)-RNAs in CTV-induced diseases, considerable research efforts had to be devoted to the engineering of the h

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