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Journal articles on the topic 'ISC process'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Amin, Ruhul. "Handling Instance Spanning Constraints in Compliance Management." ABC Journal of Advanced Research 8, no. 2 (2019): 95–108. http://dx.doi.org/10.18034/abcjar.v8i2.522.

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Instance spanning constraints refers to instruments to establish controls during multiple instances in or several processes. Many business entities crave an established ISC support system. Take, for instance, the bundling and unbundling of cargo from various logistics processes or the dependence of various examinations in medical treatment systems. During such systems, non-compliance with the ISC would lead to immense consequences and penalties, which can be fatal if it occurs in the medical field. ISC can also occur from process execution logs. Business execution store execution information f

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2

Kuzina, D. M., Ch Yuan, D. K. Nurgaliev, et al. "Effect of in-situ combustion process on the magnetic properties and composition of rock." SOCAR Proceedings, SI2 (December 30, 2021): 57–64. http://dx.doi.org/10.5510/ogp2021si200568.

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In-situ combustion (ISC) is a proved, effective method for enhanced oil recovery (EOR). In our previous work, we studied the feasibility of ISC process for heavy oil recovery in Nurlat Oil Field (Tatneft oil company, Russia) regarding to oil recovery, in-situ oil upgrading, stability of combustion front, etc. In this work, we investigated the effect of ISC process on the rock properties and composition. We found that magnetic minerals can be in-situ formed in rock during combustion process of oils. The formation of magnetic minerals in rock depends on temperature, heating time, and oil environ

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Fadaei, H., G. Debenest, A. M. M. Kamp, M. Quintard, and G. Renard. "How the In-Situ Combustion Process Works in a Fractured System: 2D Core- and Block-Scale Simulation." SPE Reservoir Evaluation & Engineering 13, no. 01 (2010): 118–30. http://dx.doi.org/10.2118/117645-pa.

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Summary Simulation of an in-situ combustion (ISC) process was performed for a fractured system at core and matrix-block scales. The aim of this work was: (1) To predict the ISC extinction/propagation condition(s), (2) understand the mechanism of oil recovery, and (3) provide some guidelines for ISC upscaling for a fractured system. The study was based on a fine-grid, single-porosity, multiphase, and multicomponent simulation using a thermal reservoir simulator. First, the simulator was validated for 1D combustion using the corresponding analytical solutions. 2D combustion was validated using e

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4

Li, Jiani, Wei Li, Jinyang Song, Yong Chen, Lubing Wang, and Jun Xu. "Accurate Measurement of the Contact Resistance During Internal Short Circuit in Lithium-Ion Batteries." Journal of The Electrochemical Society 169, no. 2 (2022): 020505. http://dx.doi.org/10.1149/1945-7111/ac4c79.

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Accurate internal short circuit (ISC) resistance measurement is of vital importance to understanding and modeling the ISC process and consequent thermal runaway (TR) behaviors. The current measurement of ISC resistance usually cannot quantify the contact resistance of two directly-involved parties for the ISC, and the measured ISC resistance generally contains additional components (depending on the ISC modes). To this end, we propose a novel experimental methodology to accurately quantify the contact resistance during ISC. By a series of auxiliary experiments, we exclude the resistance contri

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Srinivasa Reddy, Devarapu, and Govindarajan Suresh Kumar. "A Comprehensive Analysis on Thermal and Kinetic Aspects of In Situ Combustion: Numerical Approach." Applied Mechanics and Materials 592-594 (July 2014): 1393–97. http://dx.doi.org/10.4028/www.scientific.net/amm.592-594.1393.

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In-Situ Combustion (ISC) thermal Enhanced Oil Recovery (EOR) methods are aimed at increasing the oil recoveries of heavy oil reserves that are expected to play an instrumental role in near future in meeting the world’s energy demand. The complex multiphase heat and reactive mass transport necessitate a clear understanding of thermal and kinetic models used in modeling of ISC process. A finite difference based numerical analysis is carried out on heat loss and selective productions of light oil components during ISC, which showed a significant effect on peak temperature, thermal front propagati

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Zhu, Zhouyuan, Yanni Liu, Canhua Liu, and Anthony R. Kovscek. "In-Situ Combustion Frontal Stability Analysis." SPE Journal 26, no. 04 (2021): 2271–86. http://dx.doi.org/10.2118/195318-pa.

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Summary Because of complex chemical reactions and multiphase flow physics, the displacement front stability for in-situ combustion (ISC) enhanced oil recovery (EOR) processes are not well understood. In this work, theory and numerical simulation validation are presented to establish an analytical frontal stability criterion for ISC processes. First, the four influencing factors for ISC displacement stability are analyzed: viscous force, heat conduction, matrix permeability changes caused by coke deposition, and gravity. A thorough analysis of the different zones and displacement fronts in a ty

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7

Branoiu, Gheorghe, Florinel Dinu, Maria Stoicescu, Iuliana Ghetiu, and Doru Stoianovici. "Half a century of continuous oil production by in-situ combustion in Romania – case study Suplacu de Barcau field." MATEC Web of Conferences 343 (2021): 09009. http://dx.doi.org/10.1051/matecconf/202134309009.

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Thermal oil recovery is a special technique belonging to Enhanced Oil Recovery (EOR) methods and includes steam flooding, cyclic steam stimulation, and in-situ combustion (fire flooding) applied especially in the heavy oil reservoirs. Starting 1970 in-situ combustion (ISC) process has been successfully applied continuously in the Suplacu de Barcau oil field, currently this one representing the most important reservoir operated by ISC in the world. Suplacu de Barcau field is a shallow clastic Pliocene, heavy oil reservoir, located in the North-Western Romania and geologically belonging to Easte

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Xiao, Xiao, Kaiyue Ye, Muhammad Imran, and Jianzhang Zhao. "Recent Development of Heavy Atom-Free Triplet Photosensitizers for Photodynamic Therapy." Applied Sciences 12, no. 19 (2022): 9933. http://dx.doi.org/10.3390/app12199933.

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Photodynamic therapy (PDT) is an attractive method for cancer treatment. Triplet photosensitizers (PSs) are critical for this method; upon photoexcitation, efficient intersystem crossing (ISC) occurs for triplet PSs, the triplet-excited state of the triplet PSs is populated, then via intermolecular triplet energy transfer, the O2, in triplet-spin multiplicity at ground state, is sensitized to the singlet-excited state, i.e., singlet oxygen (1O2) is produced. This strong reactive oxygen species (ROS) will oxidize the biomolecules in the tumor tissue. Thus, the design of novel triplet PSs as eff

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9

Wolff, A. C., U. Kutscha, T. Wetter, P. Knaup, and S. Garde. "CSI-ISC." Methods of Information in Medicine 45, no. 01 (2006): 10–18. http://dx.doi.org/10.1055/s-0038-1634031.

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Summary Objectives: The introduction of information system components (ISCs) usually leads to a change in existing processes, e.g. processes of patient care. These processes might become even more complex and variable than before. An early participation of end users and a better understanding of human factors during design and introduction of ISCs are key factors for a successful introduction of ISCs in health care. Nonetheless no specialized methods have been developed until now to systematically support the integration of ISCs in existing processes of patient care while taking into account t

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10

Wong, S. M., R. P. Lindeman, S. Parangi, and H. S. Chase. "Role of calcium in mediating action of carbachol in T84 cells." American Journal of Physiology-Cell Physiology 257, no. 5 (1989): C976—C985. http://dx.doi.org/10.1152/ajpcell.1989.257.5.c976.

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To examine the role of calcium in mediating carbachol's action in secretory epithelia, we simultaneously measured intracellular free [Ca] [( Ca]i) and transepithelial chloride transport in T84 cells grown on collagen-coated filters. [Ca]i was measured with fura-2 and fluorescence microscopy and expressed as a relative value [( Ca]'i) normalized to control. Chloride transport was measured as the short-circuit current (Isc) with a voltage clamp. Monolayers were pretreated with cyclic AMP to augment the response of Isc to carbachol, a procedure that did not qualitatively change the response of th

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11

Balhi, Salma, and Mohamed Khalil Mrabet. "Teaching patients clean intermittent self-catheterisation: key points." British Journal of Community Nursing 25, no. 12 (2020): 586–93. http://dx.doi.org/10.12968/bjcn.2020.25.12.586.

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Intermittent self-catheterisation (ISC) is recognised as the gold standard for the treatment of neurological bladders. ISC involves the introduction of a catheter by the patient into the bladder and its immediate removal when drainage stops. This process needs to be repeated four to six times a day. Therapeutic patient education (TPE) is commonly used nowadays to treat and care for patients with chronic disease. Community nurses can play an active role in introducing ISC to patients and teaching them to perform it. This review emphasises the important points to consider when teaching patients

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Lapene, Alexandre, Louis Castanier, Gerald Debenest, Michel Yves Quintard, Arjan Matheus Kamp, and Bernard Corre. "Effects of Steam on Heavy Oil Combustion." SPE Reservoir Evaluation & Engineering 12, no. 04 (2009): 508–17. http://dx.doi.org/10.2118/118800-pa.

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Summary In-Situ Combustion. In-situ combustion (ISC) is an enhanced oil-recovery method. Enhanced oil recovery is broadly described as a group of techniques used to extract crude oil from the subsurface by the injection of substances not originally present in the reservoir with or without the introduction of extraneous energy (Lake 1996). During ISC, a combustion front is propagated through the reservoir by injected air. The heat generated results in higher temperatures leading to a reduction in oil viscosity and an increase of oil mobility. There are two types of ISC processes, dry and wet co

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Turta, A. T., and A. K. Singhal. "Reservoir Engineering Aspects of Light-Oil Recovery by Air Injection." SPE Reservoir Evaluation & Engineering 4, no. 04 (2001): 336–44. http://dx.doi.org/10.2118/72503-pa.

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Summary This paper addresses the reservoir engineering aspects of air injection as an enhanced oil recovery technique for light-oil reservoirs. In its most successful form, the process has been applied in deep, carbonate reservoirs. The development of this process in conjunction with an application of the in-situ combustion (ISC) process to light-oil reservoirs, as well as the main mechanisms pertaining to ISC and to gas miscible flooding, are analyzed. It is seen that various air-injection processes (AIP's) can be classified, depending on their spontaneous ignition potential and gas miscibili

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14

Bogomolov, Alexandr S., Vladislav M. Rogoveshko, and Alexey V. Baklanov. "Fast intersystem crossing in the tetracene dimers as a source of “dark” state." AIP Advances 13, no. 1 (2023): 015102. http://dx.doi.org/10.1063/5.0121337.

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Tetracene (Tc) is a prototype material undergoing singlet fission (SF), the formation of a pair of triplet excitons from a singlet exciton. The tetracene dimer Tc2 is supposed to be a structural unit providing SF behavior. This work is devoted to the study of the mechanism of singlet exciton decay in van der Waals dimers of Tc2. A nanosecond pump-probe approach is used, tuning both pumping and probing wavelengths. It is shown that the photoexcitation of both the Tc monomer and dimer gives rise to a triplet Tc(T1) with very similar photoionization spectra, indicating an intersystem crossing (IS

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15

Sun, Hong Jun, Shi Qing Hu, and Pei Wu Li. "ISC Application in Heavy Oil Reservoir after CSS." Advanced Materials Research 962-965 (June 2014): 443–47. http://dx.doi.org/10.4028/www.scientific.net/amr.962-965.443.

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In order to improve the flowability of crude oil, heavy oil reservoir usually developed by steam injection. While this process produces a lot of greenhouse gases. To deep reservoir, heat loss in the wellbore tends to more severe and thermal efficiency is lower. In-situ Combustion (ISC) is featured by heavy components’ combustion, high thermal efficiency and high oil recovery. Those advantages are outstanding especially in the aspects of improving thermal efficiency and reducing greenhouse gas emissions. This paper researched on ISC EOR process in a complex fault block, including reservoir desi

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Li, Sheng Zhi, Jie Xu, Yuan De Yin, J. G. Xue, and Y. Feng. "The Study of Inner Surface Crack Formation of Seamless Modified 9Cr-1Mo Tube Rolled on Mandrel Mill and Its Application." Materials Science Forum 561-565 (October 2007): 61–64. http://dx.doi.org/10.4028/www.scientific.net/msf.561-565.61.

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The hot workability of modified 9Cr-1Mo, as a grade of heat resistant steels, is inferior to that of low-alloy steel, so the inner surface crack (ISC) easily occurs in seamless boiler tubes produced by the Mandrel Mill under improper rolling conditions. With the aid of FEM, the metal flow status during the rolling process was analyzed in 140mm 8-stand mandrel mill of Bao Steel. Both the metallographic shape and size of the ISC together with the result from the simulation show that the ISC of seamless tube forms at the elongation stage of shell. The mechanism of the ISC was discussed. With its

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Bonanno, J. A., S. D. Klyce, and E. J. Cragoe. "Mechanism of chloride uptake in rabbit corneal epithelium." American Journal of Physiology-Cell Physiology 257, no. 2 (1989): C290—C296. http://dx.doi.org/10.1152/ajpcell.1989.257.2.c290.

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The mechanism of chloride uptake at the basal membrane (stromal side) of rabbit corneal epithelium was examined by observing the effects of ion transport inhibitors and ion concentrations on the stimulated epithelial short-circuit current (Isc). Loop diuretics inhibited the theophylline-stimulated peak and sustained Isc. Treatment with 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS, 0.2 mM) and/or 5-(N,N-dimethyl)amiloride (0.1 mM) as well as the potent anion exchange inhibitor, 5c(+)[(2,3,9,9a-tetrahydro-1H-fluoren-7-yl)oxy]acetic acid (0.01 mM), had no significant effect on Isc. Thes

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18

Riabokin, Maryna, Oleksiy Blyuma, and Yevgen Kotukh. "Metodological and software support for the implementation of electronic document circulation at the level of local budgets using the “ISC Local budget” software." Fìnansi Ukraïni 2024, no. 5 (2024): 71–91. http://dx.doi.org/10.33763/finukr2024.05.071.

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Introduction. The effectiveness of local self-government bodies directly depends on the availability of an appropriate information base and the possibility of using digital tools. In conditions of armed conflict, the implementation of electronic documents into the budgetary process at the local level becomes particularly important, as there is a significant risk of document loss and restricted access to them. Problem Statement. Currently, there is a lack of methodology and practice for electronic document circulation at the level of local budgets in Ukraine using corresponding software product

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Martin, Isabel, Diego Saenz del Castillo, Antonio Fernandez, and Alfredo Güemes. "Advanced Thermoplastic Composite Manufacturing by In-Situ Consolidation: A Review." Journal of Composites Science 4, no. 4 (2020): 149. http://dx.doi.org/10.3390/jcs4040149.

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This article provides an overview of the evolution of the in-situ consolidation (ISC) process over time. This evolution is intimately linked with the advancements in each of the steps of the ISC manufacturing process, is additive in nature, and is limited by the orthotropic nature of composite materials and the physicochemical behavior of the thermoplastic matrix. This review covers four key topics: (a) Thermal models—simulation tools are critical to understand a process with such large spatial gradients and fast changes. Heating systems once marked a turning point in the development of indust

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Lill, Roland. "Mitochondriale und zytosolische Systeme der Eisen-Schwefel-Proteinbiogenese." BIOspektrum 31, no. 1 (2025): 18–22. https://doi.org/10.1007/s12268-025-2371-6.

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Abstract Iron-sulfur (FeS) clusters require a complex biosynthesis pathway, despite the simplicity of these versatile, inorganic protein cofactors. The process starts in mitochondria by action of the iron-sulfur cluster assembly (ISC) machinery and is the essential and minimal function of these organelles. The ISC system further assists the cytosolic iron-sulfur protein assembly (CIA) system in maturing FeS proteins in both cytosol and nucleus. Here, I briefly summarize our current mechanistic knowledge of this essential process of life.

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Chao, A. C., A. R. Koch, and D. F. Moffett. "Basal membrane uptake in potassium-secreting cells of midgut of tobacco hornworm (Manduca sexta)." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 258, no. 1 (1990): R112—R119. http://dx.doi.org/10.1152/ajpregu.1990.258.1.r112.

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Basal membrane voltage (Vb), intracellular K+ activity [(K+)i], and short-circuit current (Isc) were measured in isolated posterior midguts of Manduca sexta wherein Isc is a measured of active secretion of K+ from blood into lumen. When bathed in 32 mM K+ and exposed to 100% O2, average values were Isc = 244 microAmp/cm2, Vb = -33.1 mV, and (K+)i = 88.6 mM. The electrochemical gradient across the basal membrane (d mu) averaged +5.8 mV (a gradient favorable for K+ entry). Exposure to 5% O2 led to a new steady state in which Isc = 71 microAmp/cm2, Vb = -18.7 mV, and (K+)i = 99.4 mM. During hypox

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Chen, Qun, Jeremy Thompson, Ying Hu, Joseph Dean, and Edward J. Lesnefsky. "Inhibition of the ubiquitous calpains protects complex I activity and enables improved mitophagy in the heart following ischemia-reperfusion." American Journal of Physiology-Cell Physiology 317, no. 5 (2019): C910—C921. http://dx.doi.org/10.1152/ajpcell.00190.2019.

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Activation of calpain 1 (CPN1) and calpain 2 (CPN2) contributes to cardiac injury during ischemia (ISC) and reperfusion (REP). Complex I activity is decreased in heart mitochondria following ISC-REP. CPN1 and CPN2 are ubiquitous calpains that exist in both cytosol (cs)-CPN1 and 2 and mitochondria (mit)-CPN1 and 2. Recent work shows that the complex I subunit (NDUFS7) is a potential substrate of the mit-CPN1. We asked whether ISC-REP led to decreased complex I activity via proteolysis of the NDUFS7 subunit via activation of mit-CPN1 and -2. Activation of cs-CPN1 and -2 decreases mitophagy in he

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Cao, Rui, Zhengjie Zhang, Jiayuan Lin, et al. "Reliable Online Internal Short Circuit Diagnosis on Lithium-Ion Battery Packs via Voltage Anomaly Detection Based on the Mean-Difference Model and the Adaptive Prediction Algorithm." Batteries 8, no. 11 (2022): 224. http://dx.doi.org/10.3390/batteries8110224.

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The safety issue of lithium-ion batteries is a great challenge for the applications of EVs. The internal short circuit (ISC) of lithium-ion batteries is regarded as one of the main reasons for the lithium-ion batteries failure. However, the online ISC diagnosis algorithm for real vehicle data remains highly imperfect at present. Based on the onboard data from the cloud battery management system (BMS), this work proposes an ISC diagnosis algorithm for battery packs with high accuracy and high robustness via voltage anomaly detection. The mean-difference model (MDM) is applied to characterize la

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Kopecek, Radovan, Florian Buchholz, Valentin D. Mihailetchi, et al. "Interdigitated Back Contact Technology as Final Evolution for Industrial Crystalline Single-Junction Silicon Solar Cell." Solar 3, no. 1 (2022): 1–14. http://dx.doi.org/10.3390/solar3010001.

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We present our own Interdigitated Back Contact (IBC) technology, which was developed at ISC Konstanz and implemented in mass production with and at SPIC Solar in Xining, China, with production efficiencies of over 24%. To our knowledge, this is the highest efficiency achieved in the mass production of crystalline silicon solar cells without the use of charge-carrier-selective contacts. With an adapted screen-printing sequence, it is possible to achieve open-circuit voltages of over 700 mV. Advanced module technology has been developed for the IBC interconnection, which is ultimately simpler th

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Prozorov, Valery V. "An inner silen scene in autocommunication." International Journal “Speech Genres” 20, no. 2 (46) (2025): 161–70. https://doi.org/10.18500/2311-0740-2025-20-2-46-161-170.

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The present article continues and develops the topic of the article “A Silent Scene in view of the speech genre theory”. The phenomenon of an inner silent scene (ISC) remarkably enhances the autocommunicative dynamism of inner speech. The basis for an ISC can be seen in critical moments within our verbal and thinking activities – new inner and outer signals causing more or less meaningful reorientation of our attention. From the point of view of basic script components, an ISC originally presupposes a customary and relatively even thinking process able to be interrupted with an unexpected gues

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Smith, P. L., M. A. Cascairo, and S. K. Sullivan. "Sodium dependence of luminal alkalinization by rabbit ileal mucosa." American Journal of Physiology-Gastrointestinal and Liver Physiology 249, no. 3 (1985): G358—G368. http://dx.doi.org/10.1152/ajpgi.1985.249.3.g358.

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Stripped rabbit ileal mucosa was studied in vitro in Ussing chambers under short-circuit conditions using the pH-stat technique to determine basal rates of luminal alkalinization; the contribution of the shunt pathway to the alkalinization process; the effects of Na, Cl, or HCO3 removal from the bathing solutions on luminal alkalinization; and the effects of epinephrine, ouabain, 4,4'-diisothiocyanostilbene-2,2'-disulfonate (DIDS), acetazolamide, prostaglandin E1 (PGE1), A23187, sugars, or amino acids on the alkalinization process. Results from these studies reveal that, under basal conditions

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Yang, Chuanxiu, Lijing Su, Yang Wang, and Lin Liu. "UTP regulation of ion transport in alveolar epithelial cells involves distinct mechanisms." American Journal of Physiology-Lung Cellular and Molecular Physiology 297, no. 3 (2009): L439—L454. http://dx.doi.org/10.1152/ajplung.90268.2008.

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UTP is known to regulate alveolar fluid clearance. However, the relative contribution of alveolar type I cells and type II cells to this process is unknown. In this study, we investigated the effects of UTP on ion transport in type I-like cell (AEC I) and type II-like cell (AEC II) monolayers. Luminal treatment of cell monolayers with UTP increased short-circuit current ( Isc) of AEC II but decreased Isc of AEC I. The Cl− channel blockers NPPB and DIDS inhibited the UTP-induced changes in Isc (Δ Isc) in both types of cells. Amiloride, an inhibitor of epithelial Na+ channels (ENaC), abolished t

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Karo, I. M. K., M. Y. Fajari, N. U. Fadhilah, and W. Y. Wardani. "Benchmarking Naïve Bayes and ID3 Algorithm for Prediction Student Scholarship." IOP Conference Series: Materials Science and Engineering 1232, no. 1 (2022): 012002. http://dx.doi.org/10.1088/1757-899x/1232/1/012002.

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Abstract Student scholarship through Indonesian smart cards (ISC) is a cash donation scholarship for all student in range 6-21 years old as a solution of destitute child or potential dropouts. Currently the large student data stored in educational database. The data was used to determine feasible receiver ISC. Manual prediction by human take long time and potentially human error. This paper aim to predict feasible receiver ISC by using educational data mining. Source of data come from a senior high school database in Riau Province, Indonesia. In this paper we compared two algorithms (Naïve Bay

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Grabow, Jens, Jacob Klink, Ralf Benger, Ines Hauer, and Hans-Peter Beck. "Particle Contamination in Commercial Lithium-Ion Cells—Risk Assessment with Focus on Internal Short Circuits and Replication by Currently Discussed Trigger Methods." Batteries 9, no. 1 (2022): 9. http://dx.doi.org/10.3390/batteries9010009.

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A possible contamination with impurities or material weak points generated in cell production of lithium-ion batteries increases the risk of spontaneous internal short circuits (ISC). An ISC can lead to a sudden thermal runaway (TR) of the cell, thereby making these faults especially dangerous. Evaluation regarding the criticality of an ISC, the development of detection methods for timely fault warning and possible protection concepts require a realistic failure replication for general validation. Various trigger methods are currently discussed to reproduce these ISC failure cases, but without

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Wang, Rong, Kun Gong, Ruihong Liu, et al. "Spectral properties and photophysical processes of meso styryl substituent triphenylamine-porphyrin derivatives." Journal of Porphyrins and Phthalocyanines 26, no. 06n07 (2022): 469–84. http://dx.doi.org/10.1142/s1088424622500353.

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This work reports the synthesis and spectral properties of meso-styryl substituted triphenylamine-porphyrin derivatives, mP-BLP, mPPC-BLP and their metal coordinated complexes. The photophysical processes were analyzed and related to the meso-groups and centre metal ions. The meso styryl substituent in mP-BLP and its complexes are able to extend the conjugation of porphyrin macrocycle to the styryl motif, increase light harvesting ability and accelerate intersystem crossing (ISC) process. A large dihedral angle between the meso-styryl group and porphyrin macrocycle would prohibit the delocaliz

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Ballard, S. T., and A. E. Taylor. "Bioelectric properties of proximal bronchiolar epithelium." American Journal of Physiology-Lung Cellular and Molecular Physiology 267, no. 1 (1994): L79—L84. http://dx.doi.org/10.1152/ajplung.1994.267.1.l79.

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Distal airway epithelium is widely believed to secrete ions and liquid into the airspace, although this process has never been demonstrated in intact small airways. To determine the characteristics of active ion transport in distal airway epithelium, the effects of selective inhibitors of active Na+ absorption and Cl- secretion on the bioelectric properties of intact proximal bronchiolar epithelium were evaluated. Large bronchioles (450-1,200 microns outside diameter, 1.5-5.0 mm length) were excised from 4- to 8-wk-old pigs, cannulated with glass microcannulas, and perfused. Transepithelial po

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Weiler, Benjamin Dennis, Marie-Christin Brück, Isabell Kothe, Eckhard Bill, Roland Lill, and Ulrich Mühlenhoff. "Mitochondrial [4Fe-4S] protein assembly involves reductive [2Fe-2S] cluster fusion on ISCA1–ISCA2 by electron flow from ferredoxin FDX2." Proceedings of the National Academy of Sciences 117, no. 34 (2020): 20555–65. http://dx.doi.org/10.1073/pnas.2003982117.

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The essential process of iron-sulfur (Fe/S) cluster assembly (ISC) in mitochondria occurs in three major phases. First, [2Fe-2S] clusters are synthesized on the scaffold protein ISCU2; second, these clusters are transferred to the monothiol glutaredoxin GLRX5 by an Hsp70 system followed by insertion into [2Fe-2S] apoproteins; third, [4Fe-4S] clusters are formed involving the ISC proteins ISCA1–ISCA2–IBA57 followed by target-specific apoprotein insertion. The third phase is poorly characterized biochemically, because previous in vitro assembly reactions involved artificial reductants and lacked

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Takashima, Shuichiro, Masanori Kadowaki, Kazutoshi Aoyama, et al. "The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells." Journal of Experimental Medicine 208, no. 2 (2011): 285–94. http://dx.doi.org/10.1084/jem.20101559.

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Graft-versus-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation (BMT), and damage to the gastrointestinal (GI) tract plays a critical role in amplifying systemic disease. Intestinal stem cells (ISCs) play a pivotal role not only in physiological tissue renewal but also in regeneration of the intestinal epithelium after injury. In this study, we have discovered that pretransplant conditioning regimen damaged ISCs; however, the ISCs rapidly recovered and restored the normal architecture of the intestine. ISCs are targets of GVHD, and this process of ISC recover

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Fong, P., A. C. Chao, and J. H. Widdicombe. "Potassium dependence of Na-Cl cotransport in dog tracheal epithelium." American Journal of Physiology-Lung Cellular and Molecular Physiology 261, no. 4 (1991): L290—L295. http://dx.doi.org/10.1152/ajplung.1991.261.4.l290.

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In confluent primary cultures of dog tracheal epithelium, we tested whether Cl entry across the basolateral membrane is by cotransport with K. Two approaches were taken. First, we measured the inhibition of short-circuit current (Isc) by the K channel inhibitor, Ba2+. Consistent with Na-K-2Cl cotransport, maximal doses of Ba2+ inhibited five-sixths of Isc in tissues previously stimulated to secrete Cl; only two-thirds of Isc should be sensitive to Ba2+ if NaCl cotransport is the entry mechanism. Second, we measured basolateral 86Rb uptake and demonstrated inhibition by bumetanide, an inhibitor

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Ning, Ya-Ru, Xi Zhao, Xian-Tong Tang, et al. "Investigations of microscopic mechanisms in exciplex-based devices with isomers of mCBP and CBP as donors via magneto-electroluminescence." Acta Physica Sinica 71, no. 8 (2022): 087201. http://dx.doi.org/10.7498/aps.71.20212068.

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The mCBP and CBP are two kinds of isomers containing carbazole groups and often used as the device hosts for fluorescence and phosphorescence emission. However, there are little studies on the microscopic mechanisms of exciplex-type devices based on mCBP or CBP. In this paper, the isomers of mCBP and CBP are used as donors and the PO-T2T is selected as an acceptor. The two kinds of exciplex-based devices are fabricated according to a mass ratio of 1∶1, which are respectively referred to as device 1 (Dev. 1) and device 2 (Dev. 2). Their magneto-electroluminescence (MEL) curves are measured at d

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Duan, Xudong, Huacui Wang, Yikai Jia, Lubing Wang, Binghe Liu, and Jun Xu. "A Multiphysics Understanding of Internal Short Circuit Mechanisms in Lithium-Ion Batteries upon Mechanical Stress Abuse." ECS Meeting Abstracts MA2022-02, no. 5 (2022): 558. http://dx.doi.org/10.1149/ma2022-025558mtgabs.

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Lithium-ion batteries (LIBs) have played an increasingly dominant role in the current mobile society. Due to the risky safety testing procedure, ultra-rigorous demands of the testing facility, and complicated multiphysics nature of the safety issues, lack of high-fidelity models to describe the safety behaviors of lithium-ion batteries upon abusive loading has significantly deferred the further application of LIBs. Herein, firstly, mechanical behaviors of the battery component materials are characterized by both in-situ and post-mortem experiments. Then, we reveal the formation process of vari

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Fogarty, Steve. "Process safety common lead metrics: implementing and learning." APPEA Journal 56, no. 2 (2016): 544. http://dx.doi.org/10.1071/aj15050.

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No matter which major accident event investigation is looked into, some common themes concerning the requirements for process safety metrics present themselves. For example, the recent Macondo investigation by the US Chemical Safety Board (CSB) examined both API 754 and IOGP 456, and re-iterated that metrics need to be developed to capture the health of barriers and management systems. The effectiveness of barriers and management systems needs to be assessed, as does the frequency that these barriers are being called upon to make sure that the risk is being properly managed. Both API 754 and I

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O'Hara, Paul. "Spin Entanglement – A Unifying Principle for Superconductors and Molecular Bonding." Recent Progress in Materials 06, no. 02 (2024): 1–15. http://dx.doi.org/10.21926/rpm.2402012.

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The spin-statistics theorem is generalized to include quantum entanglement. Specifically, within the context of spin entanglement, we prove that isotropically spin-correlated (ISC) states must occur in pairs. This pairing process can be composed of parallel or anti-parallel states. Consequently, the article proposes using ISC states as a unifying principle to explain better Bose-Einstein condensates, the theory of superconductivity, and molecular and atomic orbitals, all of which involve a pairing process. The theoretical framework is established in sections 1 and 2. The other qualitative sect

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Skovran, Elizabeth, C. T. Lauhon, and D. M. Downs. "Lack of YggX Results in Chronic Oxidative Stress and Uncovers Subtle Defects in Fe-S Cluster Metabolism in Salmonella enterica." Journal of Bacteriology 186, no. 22 (2004): 7626–34. http://dx.doi.org/10.1128/jb.186.22.7626-7634.2004.

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ABSTRACT As components involved in Fe-S cluster metabolism are described, the challenge becomes defining the integrated process that occurs in vivo based on the individual functions characterized in vitro. Strains lacking yggX have been used here to mimic chronic oxidative stress and uncover subtle defects in Fe-S cluster metabolism. We describe the in vivo similarities and differences between isc mutants, which have a known function in cluster assembly, and mutants disrupted in four additional loci, gshA, apbC, apbE, and rseC. The latter mutants share similarities with isc mutants: (i) a sens

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Sei, Yoshitatsu, Jianying Feng, Carson C. Chow, and Stephen A. Wank. "Asymmetric cell division-dominant neutral drift model for normal intestinal stem cell homeostasis." American Journal of Physiology-Gastrointestinal and Liver Physiology 316, no. 1 (2019): G64—G74. http://dx.doi.org/10.1152/ajpgi.00242.2018.

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The normal intestinal epithelium is continuously regenerated at a rapid rate from actively cycling Lgr5-expressing intestinal stem cells (ISCs) that reside at the crypt base. Recent mathematical modeling based on several lineage-tracing studies in mice shows that the symmetric cell division-dominant neutral drift model fits well with the observed in vivo growth of ISC clones and suggests that symmetric divisions are central to ISC homeostasis. However, other studies suggest a critical role for asymmetric cell division in the maintenance of ISC homeostasis in vivo. Here, we show that the stocha

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Onitiri, M. A., and S. M. Adedayo. "Compressive behaviour of polypropylene filled with iron ore tailings." Journal of Engineering, Design and Technology 13, no. 2 (2015): 198–212. http://dx.doi.org/10.1108/jedt-12-2012-0056.

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Purpose – This paper aims to produce iron ore tailings reinforced polypropylene composites (ITR-PPCs) from conventional compo-casting (CC) and a proposed compo-indirect squeeze casting (C-ISC) processes. It intends to quantify the compressive behaviour of ITR-PPC with respect to production process, iron ore tailings volume and particle size inclusion in polypropylene (PP) through controlled material and compressive testing. The study aims to provide useful information on possibility of the use of ITR-PP for compressive applications which will culminate to judicious use of iron ore tailings tha

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Huang, Wenhuan, Xuepeng Zhang, Biao Chen, et al. "Boosting the triplet activity of heavy-atom-free difluoroboron dibenzoylmethane via sp3 oxygen-bridged electron donors." Chemical Communications 55, no. 1 (2019): 67–70. http://dx.doi.org/10.1039/c8cc08346k.

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Shan, Haiou, and Yongqiang Zhu. "Gas Pipeline Leakage Detection Method Based on IUPLCD and GS-TBSVM." Processes 11, no. 1 (2023): 278. http://dx.doi.org/10.3390/pr11010278.

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To improve the identification accuracy of gas pipeline leakage and reduce the false alarm rate, a pipeline leakage detection method based on improved uniform-phase local characteristic-scale decomposition (IUPLCD) and grid search algorithm-optimized twin-bounded support vector machine (GS-TBSVM) was proposed. First, the signal was decomposed into several intrinsic scale components (ISC) by the UPLCD algorithm. Then, the signal reconstruction process of UPLCD was optimized and improved according to the energy and standard deviation of the amplitude of each ISC, the ISC components dominated by t

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Mora, Minda. "Telaahan Literatur Tentang Program Perawatan Pesawat Udara." WARTA ARDHIA 38, no. 4 (2012): 356–72. http://dx.doi.org/10.25104/wa.v38i4.205.356-372.

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Maintenance is one of the most important thing in aviation. Maintenance is the process where a systems designed-in level of failure resistance is restored to or as close as economic viable to the most adequate level of the design. In order to conduct maintenance in the right way, each aircraft is required to have a Maintenance Program (MP). There are three main actors relating to the initial development of the MP, which are the manufacturer, the Industrial Steering Committee (ISC) and the Maintenance Review Board (MRB). In the manufacturers, PPH (Policies and Procedures Handbook) process for d

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Murray, Virginia. "The UNDRR/ISC Hazard Definition and Classification Review and Hazard Information Profiles and Links to the Sendai Framework, the SDGs, and the Paris Agreement." Prehospital and Disaster Medicine 38, S1 (2023): s70—s71. http://dx.doi.org/10.1017/s1049023x23002091.

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Introduction:The 'all hazards' approach that the Sendai Framework on Disaster Risk Reduction calls for ‘to strengthen technical and scientific capacity to capitalize on and consolidate existing knowledge and to develop and apply methodologies and models to assess disaster risks, vulnerabilities and exposure to all hazards;’ (paragraph 24 j)’ needed clarification.Method:Following extensive scientific consultation, the United Nations Office for Disaster Risk Reduction (UNDRR) and the International Science Council (ISC) published in 2020 the UNDRR/ISC Hazard definition and classification review.

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Lill, Roland, and Sven-A. Freibert. "Mechanisms of Mitochondrial Iron-Sulfur Protein Biogenesis." Annual Review of Biochemistry 89, no. 1 (2020): 471–99. http://dx.doi.org/10.1146/annurev-biochem-013118-111540.

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Mitochondria are essential in most eukaryotes and are involved in numerous biological functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and steroid metabolism. Work over the past two decades has uncovered the biogenesis of cellular iron-sulfur (Fe/S) proteins as the essential and minimal function of mitochondria. This process is catalyzed by the bacteria-derived iron-sulfur cluster assembly (ISC) machinery and has been dissected into three major steps: de novo synthesis of a [2Fe-2S] cluster on a scaffold protein; Hsp70 chaperone–mediated trafficking of the

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Keeler, R., and N. L. Wong. "Evidence that prostaglandin E2 stimulates chloride secretion in cultured A6 renal epithelial cells." American Journal of Physiology-Renal Physiology 250, no. 3 (1986): F511—F515. http://dx.doi.org/10.1152/ajprenal.1986.250.3.f511.

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The effects of prostaglandin E2 (PGE2) on the transport of sodium and chloride were studied in cultured A6 renal epithelial cells. PGE2 on the basolateral but not the apical surface increased transmonolayer short-circuit current (Isc) and conductance. These changes could not be inhibited with amiloride or furosemide in the apical medium. Flux measurements showed that although Isc and net flux of sodium were equal in unstimulated cells, after addition of PGE2 the current increased with no corresponding changes in bidirectional or net flux of sodium. Immersing the cells in sodium-free or chlorid

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Klein, Galit, and Batia Ben-Hador. "Impacting Employee Performance by Supporting Intrapreneurial Activities." Administrative Sciences 15, no. 6 (2025): 235. https://doi.org/10.3390/admsci15060235.

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Extensive empirical findings support the idea that intrapreneurial activity benefits employees, organizations, and society. Grounded in Self-Determination Theory (SDT), this paper analyzes the mediating role of intrapreneurial behaviors in the relationship between organizational support for intrapreneurship and employee performance and the moderating role of intra-organizational social capital (ISC) in the relationship between organizational support and intrapreneurial behaviors. Hypotheses were tested using regression analyses via Hayes’ PROCESS macro, allowing for the assessment of moderatio

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Zhao, Fajun, Shun Zhu, Changjiang Zhang, Zian Yang, Mingze Sun, and Hong Zhang. "Research on the Variation Laws of In Situ Combustion in Heavy Oil Reservoirs with Different Oil Saturations." Processes 13, no. 1 (2025): 147. https://doi.org/10.3390/pr13010147.

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This study investigates the behavior of heavy oil reservoirs under varying oil saturation conditions through laboratory-scale in situ combustion (ISC) physical simulation experiments. The research focuses on the propagation stability of the combustion front and key parameters influencing the in situ combustion process, with a systematic examination of crude oil composition changes and upgrading mechanisms during ISC. By employing gas chromatography (GC) and infrared spectroscopy (IR) analyses, this study evaluates the transformation of saturated hydrocarbons, aromatic hydrocarbons, resins, and

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Kotarba, Joseph A., and Kevin Wooten. "The innovation scorecard for continuous improvement applied to translational science." Journal of Clinical and Translational Science 1, no. 5 (2017): 296–300. http://dx.doi.org/10.1017/cts.2017.297.

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IntroductionThis paper reports on the baseline stage of a qualitative evaluation of the application of the Innovative Scorecard (ISC) to the Clinical and Translational Science Award (CTSA) at the University of Texas Medical Branch (UTMB) at Galveston. The ISC is adopted from the established Balanced Scorecard system for strategic planning and performance management. In formulating the evaluation, we focused on the organizational identity literature.MethodsThe initial evaluation consisted of a series of semi-structured interviews with 22 participants of the ISC Boot Camp conducted in July 2015.

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