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Journal articles on the topic 'ISDF'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Zapotoczna, Marta, Simon Heilbronner, Pietro Speziale, and Timothy J. Foster. "Iron-Regulated Surface Determinant (Isd) Proteins of Staphylococcus lugdunensis." Journal of Bacteriology 194, no. 23 (2012): 6453–67. http://dx.doi.org/10.1128/jb.01195-12.

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ABSTRACTStaphylococcus lugdunensisis the only coagulase-negativeStaphylococcusspecies with a locus encoding iron-regulated surface determinant (Isd) proteins. InStaphylococcus aureus, the Isd proteins capture heme from hemoglobin and transfer it across the wall to a membrane-bound transporter, which delivers it into the cytoplasm, where heme oxygenases release iron. The Isd proteins ofS. lugdunensisare expressed under iron-restricted conditions. We propose thatS. lugdunensisIsdB and IsdC proteins perform the same functions as those ofS. aureus.S. lugdunensisIsdB is the only hemoglobin receptor

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Rios, Gloria P., and Sergio Botero. "An Integrated Indicator to Analyze Sustainability in Specialized Dairy Farms in Antioquia—Colombia." Sustainability 12, no. 22 (2020): 9595. http://dx.doi.org/10.3390/su12229595.

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An integrated sustainability indicator in specialized dairy index (IISLE) is proposed for the evaluation of these production systems in four dimensions (financial, technical, social, and environmental). This index was validated in a study carried out with information from 18 dairy farms in Antioquia, a Colombian milk production region. The analytic hierarchy process (AHP) method was applied to prioritize criteria and sub-criteria. According to the proposed dimensions, four criteria were established (financial (ISDF), technical (ISDT), social (ISDS), and environmental (ISDA)) and 30 sub-criteri

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3

DESPA, Mihai Liviu. "Formalizing the ISDF Software Development Methodology." Informatica Economica 20, no. 2/2015 (2015): 66–80. http://dx.doi.org/10.12948/issn14531305/19.2.2015.07.

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4

Torres, Victor J., Gleb Pishchany, Munir Humayun, Olaf Schneewind, and Eric P. Skaar. "Staphylococcus aureus IsdB Is a Hemoglobin Receptor Required for Heme Iron Utilization." Journal of Bacteriology 188, no. 24 (2006): 8421–29. http://dx.doi.org/10.1128/jb.01335-06.

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ABSTRACT The pathogenesis of human infections caused by the gram-positive microbe Staphylococcus aureus has been previously shown to be reliant on the acquisition of iron from host hemoproteins. The iron-regulated surface determinant system (Isd) encodes a heme transport apparatus containing three cell wall-anchored proteins (IsdA, IsdB, and IsdH) that are exposed on the staphylococcal surface and hence have the potential to interact with human hemoproteins. Here we report that S. aureus can utilize the host hemoproteins hemoglobin and myoglobin, but not hemopexin, as iron sources for bacteria

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Alkussayer, Abdulaziz, and William H. Allen. "The ISDF Framework: Towards Secure Software Development." Journal of Information Processing Systems 6, no. 1 (2010): 91–106. http://dx.doi.org/10.3745/jips.2010.6.1.091.

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6

Limpens, Maureen. "ISDF brengt internationale expertise diabetische voet samen." PodoSophia 23, no. 4 (2015): 14–17. http://dx.doi.org/10.1007/s12481-015-0070-9.

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7

Linden, Leolíbia Luana, and Marisa Bräscher. "Diagnóstico arquivístico: uma proposição metodológica a partir de instrumentos normativos de descrição arquivística." Informação & Informação 24, no. 3 (2019): 335. http://dx.doi.org/10.5433/1981-8920.2019v24n3p335.

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Introdução: Discorre sobre a importância e a necessidade de realização do diagnóstico arquivístico no que antecede qualquer intervenção arquivística no processo de gestão de documentos. Objetivo: Aborda conceitos e metodologias que a literatura da área tem utilizado na realização de diagnóstico arquivístico, a estrutura e os objetivos dos instrumentos normativos de descrição arquivística ISAD (G), ISAAR (CPF), ISDIAH e ISDF. Metodologia: Pesquisa bibliográfica que alinha as informações propostas pela literatura para desenvolvimento de diagnóstico arquivístico com a estrutura de elementos descr

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8

Miajlovic, Helen, Marta Zapotoczna, Joan A. Geoghegan, Steven W. Kerrigan, Pietro Speziale, and Timothy J. Foster. "Direct interaction of iron-regulated surface determinant IsdB of Staphylococcus aureus with the GPIIb/IIIa receptor on platelets." Microbiology 156, no. 3 (2010): 920–28. http://dx.doi.org/10.1099/mic.0.036673-0.

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The interaction of bacteria with platelets is implicated in the pathogenesis of endovascular infections, including infective endocarditis, of which Staphylococcus aureus is the leading cause. Several S. aureus surface proteins mediate aggregation of platelets by fibrinogen- or fibronectin-dependent processes, which also requires specific antibodies. In this study S. aureus was grown in iron-limited medium to mimic in vivo conditions in which iron is unavailable to pathogens. Under such conditions, a S. aureus mutant lacking the known platelet-activating surface proteins adhered directly to pla

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9

Gao, He, Jun Li, Fu Qiang Zhou, Rong Zou, and Yi Cui. "Outage Probability Analysis and Adaptive Power Allocation for ISDF MIMO Cooperation Systems." Applied Mechanics and Materials 58-60 (June 2011): 2296–302. http://dx.doi.org/10.4028/www.scientific.net/amm.58-60.2296.

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The outage probability performance is analyzed for the optimization of incremental selection decode-amplify-forward (ISDF) multi-node MIMO cooperative communication systems. Firstly, the system model for the proposed multi-node MIMO cooperative protocol. Then, the incremental selection decode-amplify-forward and optimal relay selection strategy (routing) based on the opportunistic relaying scheme is proposed. The mutual information and outage probability between source and destination nodes for the proposed scheme are formulated with the relays have the capability of maximum ratio combining (M

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10

Owen, JR, MP Campbell, MD Mott, et al. "IgG4-specific responses in patients with Staphylococcus aureus bone infections are not predictive of postoperative complications." European Cells and Materials 42 (September 22, 2021): 156–65. http://dx.doi.org/10.22203/ecm.v042a12.

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The most prevalent pathogen in bone infections is Staphylococcus aureus; its incidence and severity are partially determined by host factors. Prior studies showed that anti-glucosaminidase (Gmd) antibodies are protective in animals, and 93.3 % of patients with culture-confirmed S. aureus osteomyelitis do not have anti-Gmd levels > 10 ng/mL in serum. Infection in patients with high anti-Gmd remains unexplained. Are anti-Gmd antibodies in osteomyelitis patients of the non-opsonising, non-complement-fixing IgG4 isotype? The relative amounts of IgG4 and total IgG against Gmd and 7 other S. aure

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11

Grimoüard, Claire, and Padré Baroan-Dioumency. "Une nouvelle norme internationale pour décrire les fonctions des producteurs d'archives : ICA-ISDF." Comma 2008, no. 2 (2008): 113–23. http://dx.doi.org/10.3828/comma.2008.2.13.

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12

Mikkelsen, Jakob H., Kasper Runager, and Christian B. F. Andersen. "The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus." Journal of Biological Chemistry 295, no. 7 (2019): 1781–91. http://dx.doi.org/10.1074/jbc.ra119.011612.

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Iron is an essential nutrient for all living organisms. To acquire iron, many pathogens have developed elaborate systems to steal it from their hosts. The iron acquisition system in the opportunistic pathogen Staphylococcus aureus comprises nine proteins, called iron-regulated surface determinants (Isds). The Isd components enable S. aureus to extract heme from hemoglobin (Hb), transport it into the bacterial cytoplasm, and ultimately release iron from the porphyrin ring. IsdB and IsdH act as hemoglobin receptors and are known to actively extract heme from extracellular Hb. To limit microbial

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13

Tiedemann, Michael T., Naomi Muryoi, David E. Heinrichs, and Martin J. Stillman. "Characterization of IsdH (NEAT domain 3) and IsdB (NEAT domain 2) in Staphylococcus aureus by magnetic circular dichroism spectroscopy and electrospray ionization mass spectrometry." Journal of Porphyrins and Phthalocyanines 13, no. 10 (2009): 1006–16. http://dx.doi.org/10.1142/s1088424609001352.

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Absorption and magnetic circular dichroism (MCD) spectra, together with electrospray ionization mass spectral (ESI-MS) data are reported for the first two proteins in the Isd sequence of proteins in Staphylococcus aureus. IsdH-NEAT domain 3 (IsdH-N3) and IsdB-NEAT domain 2 (IsdB-N2) are considered to be involved in heme transport following heme scavenging from the hemoglobin of the host. The ESI-MS data show that a single heme binds to each of these NEAT domains. The charge states of the native proteins indicate that there is minimal change in conformation when heme binds to the heme-free nati

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14

Xu, Lingwei, Hao Zhang, and T. Gulliver. "Joint Transmit Antenna Selection and Power Allocation for ISDF Relaying Mobile-to-Mobile Sensor Networks." Sensors 16, no. 2 (2016): 249. http://dx.doi.org/10.3390/s16020249.

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15

Tiedemann, Michael T., Tyler B. J. Pinter, and Martin J. Stillman. "Insight into blocking heme transfer by exploiting molecular interactions in the core Isd heme transporters IsdA-NEAT, IsdC-NEAT, and IsdE of Staphylococcus aureus." Metallomics 4, no. 8 (2012): 751. http://dx.doi.org/10.1039/c2mt20067h.

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16

Farrand, Allison J., Kathryn P. Haley, Nichole M. Lareau, et al. "An Iron-Regulated Autolysin Remodels the Cell Wall To Facilitate Heme Acquisition in Staphylococcus lugdunensis." Infection and Immunity 83, no. 9 (2015): 3578–89. http://dx.doi.org/10.1128/iai.00397-15.

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Bacteria alter their cell surface in response to changing environments, including those encountered upon invasion of a host during infection. One alteration that occurs in several Gram-positive pathogens is the presentation of cell wall-anchored components of the iron-regulated surface determinant (Isd) system, which extracts heme from host hemoglobin to fulfill the bacterial requirement for iron.Staphylococcus lugdunensis, an opportunistic pathogen that causes infective endocarditis, encodes an Isd system. Unique among the known Isd systems,S. lugdunensiscontains a gene encoding a putative au

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17

Kaya, İsa, Serdal Seven, and Gökçen İlhan Ildız. "The Contributions of Temperament Characteristics to Attachment in 6-Year-Old Children." International Education Studies 13, no. 7 (2020): 156. http://dx.doi.org/10.5539/ies.v13n7p156.

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The aim of the current study is to investigate whether 6-year-old children&rsquo;s temperament predict their level of attachment. The study has a descriptive design. During the Spring term of the academic year 2017-2018, 59 children (60-72-month old) and their mothers in City of Tekirdağ (S&uuml;leymanpaşa District) volunteered to participate in the study. Demographics Form, Incomplete Stories with Doll Family and Short Temperament Scale for Children were used for the data collection. Descriptive statistics were performed to summarize the ISDF and STSC scores in the first step of the d

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18

Hurd, Alexander F., Jorge Garcia-Lara, Yvonne Rauter, Michaël Cartron, Ramlan Mohamed, and Simon J. Foster. "The iron-regulated surface proteins IsdA,IsdB, and IsdH are not required for heme iron utilization in Staphylococcus aureus." FEMS Microbiology Letters 329, no. 1 (2012): 93–100. http://dx.doi.org/10.1111/j.1574-6968.2012.02502.x.

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19

Liu, Mengyao, Wesley N. Tanaka, Hui Zhu, Gang Xie, David M. Dooley, and Benfang Lei. "Direct Hemin Transfer from IsdA to IsdC in the Iron-regulated Surface Determinant (Isd) Heme Acquisition System ofStaphylococcus aureus." Journal of Biological Chemistry 283, no. 11 (2008): 6668–76. http://dx.doi.org/10.1074/jbc.m708372200.

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20

ElFouly, Heba A., and Noha A. El Aziz. "Physical Quality of Life Benchmark for Unsafe Slums in Egypt." Sustainability in Environment 2, no. 2 (2017): 258. http://dx.doi.org/10.22158/se.v2n2p258.

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<em>Enhancing the quality of life in urban settle ments is one of the most significant challenges facing </em><em>governments. In the case of unsafe-slums, the challenge is even more problematical, as slum dwellers </em><em>not only suffer from substandard housing, devoid of basic necessities and unhealthy urban conditions, </em><em>but they are exposed to danger. This paper focuses on extracting the most significant physical </em><em>QoLindices in unsafe-slums in Egypt, taking into account the limited designated investments and the </em

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21

Pishchany, Gleb, Susan E. Dickey, and Eric P. Skaar. "Subcellular Localization of the Staphylococcus aureus Heme Iron Transport Components IsdA and IsdB." Infection and Immunity 77, no. 7 (2009): 2624–34. http://dx.doi.org/10.1128/iai.01531-08.

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ABSTRACT Staphylococcus aureus is a human pathogen that represents a tremendous threat to global public health. An important aspect of S. aureus pathogenicity is the ability to acquire iron from its host during infection. In vertebrates, iron is sequestered predominantly within heme, the majority of which is bound by hemoglobin. To acquire iron, S. aureus binds hemoglobin, removes heme, and transports it into the cytoplasm, where heme is degraded. This process is carried out by the iron-regulated surface determinant system (Isd); however, the mechanism by which hemoglobin recognition occurs is

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22

Skaar, Eric P., Andrew H. Gaspar, and Olaf Schneewind. "IsdG and IsdI, Heme-degrading Enzymes in the Cytoplasm ofStaphylococcus aureus." Journal of Biological Chemistry 279, no. 1 (2003): 436–43. http://dx.doi.org/10.1074/jbc.m307952200.

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23

Mack, John, Christie Vermeiren, David E. Heinrichs, and Martin J. Stillman. "In vivo heme scavenging by Staphylococcus aureus IsdC and IsdE proteins." Biochemical and Biophysical Research Communications 320, no. 3 (2004): 781–88. http://dx.doi.org/10.1016/j.bbrc.2004.06.025.

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24

Lee, W. C., G. Ukpabi, M. L. Reniere, E. P. Skaar, and M. E. P. Murphy. "Ruffling of metalloporphyrins bound to IsdG and IsdI, two heme-degrading enzymes." Acta Crystallographica Section A Foundations of Crystallography 64, a1 (2008): C293. http://dx.doi.org/10.1107/s0108767308090648.

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25

Pluym, Mark, Naomi Muryoi, David E. Heinrichs, and Martin J. Stillman. "Heme binding in the NEAT domains of IsdA and IsdC of Staphylococcus aureus." Journal of Inorganic Biochemistry 102, no. 3 (2008): 480–88. http://dx.doi.org/10.1016/j.jinorgbio.2007.11.011.

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26

Matsui, Toshitaka, Shusuke Nambu, Yukari Ono, Celia W. Goulding, Kouhei Tsumoto, and Masao Ikeda-Saito. "Heme Degradation by Staphylococcus aureus IsdG and IsdI Liberates Formaldehyde Rather Than Carbon Monoxide." Biochemistry 52, no. 18 (2013): 3025–27. http://dx.doi.org/10.1021/bi400382p.

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27

Kim, Hwan Keun, Andrea DeDent, Alice G. Cheng, et al. "IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge." Vaccine 28, no. 38 (2010): 6382–92. http://dx.doi.org/10.1016/j.vaccine.2010.02.097.

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28

Loutet, Slade A., Marek J. Kobylarz, Crystal H. T. Chau, and Michael E. P. Murphy. "IruO Is a Reductase for Heme Degradation by IsdI and IsdG Proteins inStaphylococcus aureus." Journal of Biological Chemistry 288, no. 36 (2013): 25749–59. http://dx.doi.org/10.1074/jbc.m113.470518.

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Lee, Woo Cheol, Michelle L. Reniere, Eric P. Skaar, and Michael E. P. Murphy. "Ruffling of Metalloporphyrins Bound to IsdG and IsdI, Two Heme-degrading Enzymes inStaphylococcus aureus." Journal of Biological Chemistry 283, no. 45 (2008): 30957–63. http://dx.doi.org/10.1074/jbc.m709486200.

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30

Moriwaki, Yoshitaka, Tohru Terada, Jose Manuel Martinez Caaveiro, et al. "2I1412 Analysis of iron and other metalloporphyrins recognition and transport mechanism among IsdH, IsdA, IsdC from Staphylococcus aureus(Heme proteins 2,The 48th Annual Meeting of the Biophysical Society of Japan)." Seibutsu Butsuri 51, supplement (2011): S89. http://dx.doi.org/10.2142/biophys.51.s89_1.

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31

Conger, Matthew A., Deepika Pokhrel, and Matthew D. Liptak. "Tight binding of heme to Staphylococcus aureus IsdG and IsdI precludes design of a competitive inhibitor." Metallomics 9, no. 5 (2017): 556–63. http://dx.doi.org/10.1039/c7mt00035a.

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32

Rauch, Sabine, Portia Gough, Hwan Keun Kim, Olaf Schneewind, and Dominique Missiakas. "Vaccine Protection of Leukopenic Mice against Staphylococcus aureus Bloodstream Infection." Infection and Immunity 82, no. 11 (2014): 4889–98. http://dx.doi.org/10.1128/iai.02328-14.

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ABSTRACTThe risk forStaphylococcus aureusbloodstream infection (BSI) is increased in immunocompromised individuals, including patients with hematologic malignancy and/or chemotherapy. Due to the emergence of antibiotic-resistant strains, designated methicillin-resistantS. aureus(MRSA), staphylococcal BSI in cancer patients is associated with high mortality; however, neither a protective vaccine nor pathogen-specific immunotherapy is currently available. Here, we modeled staphylococcal BSI in leukopenic CD-1 mice that had been treated with cyclophosphamide, a drug for leukemia and lymphoma pati

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33

De Luca, Anna, Mark Feldman, Martins Paparinskis, and Catharine Titi. "Responding to Incorrect Decision-Making in Investor-State Dispute Settlement: Policy Options." Journal of World Investment & Trade 21, no. 2-3 (2020): 374–409. http://dx.doi.org/10.1163/22119000-12340176.

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Abstract Criticism of the quality of investor-State dispute settlement (ISDS) decision-making often focuses on inconsistency (comparing ISDS decisions), and less frequently, incorrectness (evaluating individual ISDS decisions on a standalone basis). This article situates incorrect ISDS decision-making within the broader context of public international law and develops potential policy responses, guided by three considerations. First, criticism of ISDS decision-making has been significant. Second, criticism of particular ISDS decisions, even when widespread and intense, does not necessarily est

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Kipchirchir Bitok, J., and Caren Freel Meyers. "Synthesis and evaluation of stable substrate analogs as potential modulators of cyclodiphosphate synthase IspF." MedChemComm 4, no. 1 (2013): 130–34. http://dx.doi.org/10.1039/c2md20175e.

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Dallel, Radhouane, Amélie Descheemaeker, and Philippe Luccarini. "Recurrent administration of the nitric oxide donor, isosorbide dinitrate, induces a persistent cephalic cutaneous hypersensitivity: A model for migraine progression." Cephalalgia 38, no. 4 (2017): 776–85. http://dx.doi.org/10.1177/0333102417714032.

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Background A subgroup of migraineurs experience an increase in attack frequency leading to chronic migraine. Methods We assessed in rats the roles of dose and repeat administration of systemic isosorbide dinitrate (ISDN), a nitric oxide donor, on the occurrence and development of cephalic/face and extracephalic/hindpaw mechanical allodynia as a surrogate of migraine pain, and the effect of acute systemic sumatriptan and olcegepant and chronic systemic propranolol on these behavioral changes. Results A single high (H-ISDN) but not low (L-ISDN) dose of ISDN induces a reversible cephalic and extr

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36

Zaugg, Holt, and C. Jeffrey Belliston. "Assessing old and new individual study desks." Performance Measurement and Metrics 21, no. 2 (2020): 93–106. http://dx.doi.org/10.1108/pmm-12-2019-0062.

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PurposeThis paper examines student perceptions of new individual study desks (ISDs) and how they improved the students' learning experience.Design/methodology/approachThe study describes the process for developing new ISDs. When about half of the old ISDs were replaced with new ISDs, two parallel surveys were used to understand why students used the ISDs, what their experiences were and any suggested improvements.FindingsResults indicate that the new ISDs were used by students for significantly longer periods of time. They enjoyed the ambiance and amenities of the new desks, including a whiteb

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37

Bjorklund, Andrea K., Daniel Behn, Susan D. Franck, et al. "The Diversity Deficit in International Investment Arbitration." Journal of World Investment & Trade 21, no. 2-3 (2020): 410–40. http://dx.doi.org/10.1163/22119000-12340177.

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Abstract The United Nations Commission on International Trade Law (UNCITRAL) Working Group III on ISDS (Investor-State Dispute Settlement) Reform considers issues of adjudicator diversity to be an area of concern for the legitimacy of the ISDS system. Studies show that nearly all of the most prominent and repeatedly appointed arbitrators in ISDS cases are men from the Global North with significant prior experience in ISDS cases. Rather than being seen as fair, just, and devoid of bias, decisions are sometimes suspected to be the products of adjudicators who share a particular world view. This

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38

Lai, Vincent S., and Jan Guynes Clark. "Network Evolution towards ISDN Services: A Management Perspective." Journal of Information Technology 13, no. 1 (1998): 67–78. http://dx.doi.org/10.1177/026839629801300105.

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ISDN (Integrated Services Digital Network) has been recognized by technologists as a major step in the evolution of public network architecture. However, a large percentage of network users do not recognize any bottom line improvements that can result from ISDN nor do they know how to exploit the benefits of the technology. This study evaluates and summarizes the ISDN implementation experiences of nine organizations that are currently using ISDN. Along with their experiences, the study also investigated potential problems and critical success factors associated with ISDN implementation. Unders

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Waryah, Charlene Babra, Jully Gogoi-Tiwari, Kelsi Wells, et al. "Diversity of Virulence Factors Associated with West Australian Methicillin-SensitiveStaphylococcus aureusIsolates of Human Origin." BioMed Research International 2016 (2016): 1–10. http://dx.doi.org/10.1155/2016/8651918.

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An extensive array of virulence factors associated withS. aureushas contributed significantly to its success as a major nosocomial pathogen in hospitals and community causing variety of infections in affected patients. Virulence factors include immune evading capsular polysaccharides, poly-N-acetyl glucosamine, and teichoic acid in addition to damaging toxins including hemolytic toxins, enterotoxins, cytotoxins, exfoliative toxin, and microbial surface components recognizing adhesive matrix molecules (MSCRAMM). In this investigation, 31 West AustralianS. aureusisolates of human origin and 6 co

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40

Pitcher, Joe. "ISDN." Telecommunications Policy 13, no. 4 (1989): 387–88. http://dx.doi.org/10.1016/0308-5961(89)90031-1.

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41

JUNG, ACHIM, and GUO-QIANG ZHANG. "Preface." Mathematical Structures in Computer Science 27, no. 4 (2015): 459. http://dx.doi.org/10.1017/s0960129515000249.

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The International Symposium on Domain Theory (ISDT) is a conference series intended to be a forum for researchers in domain theory and its applications. Topics include topological and logical aspects of domains; categories of domains and powerdomains; continuous posets and their representations; partial orders, lattice theory and metric spaces; types, process algebra and concurrency; non-classical and partial logics; programming language semantics; applications in computer science and mathematics. This conference series was founded by Yingming Liu, Yixiang Chen, Klaus Keimel, and Guo-Qiang Zha

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Arlian, Britni M., and Juliette K. Tinker. "Mucosal Immunization with a Staphylococcus aureus IsdA-Cholera Toxin A2/B Chimera Induces Antigen-Specific Th2-Type Responses in Mice." Clinical and Vaccine Immunology 18, no. 9 (2011): 1543–51. http://dx.doi.org/10.1128/cvi.05146-11.

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ABSTRACTStaphylococcus aureusis a leading cause of opportunistic infection worldwide and a significant public health threat. The iron-regulated surface determinant A (IsdA) adhesin is essential forS. aureuscolonization on human nasal epithelial cells and plays an important role in iron acquisition and resistance to human skin defenses. Here we investigated the murine immune response to intranasal administration of a cholera toxin A2/B (CTA2/B) chimera containing IsdA. Plasmids were constructed to express the IsdA-CTA2/B chimera and control proteins inEscherichia coli. Proper construction of th

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Ythier, Mathilde, Grégory Resch, Patrice Waridel, et al. "Proteomic and Transcriptomic Profiling of Staphylococcus aureus Surface LPXTG-proteins: Correlation with agr Genotypes and Adherence Phenotypes." Molecular & Cellular Proteomics 11, no. 11 (2012): 1123–39. http://dx.doi.org/10.1074/mcp.m111.014191.

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Staphylococcus aureus infections involve numerous adhesins and toxins, which expression depends on complex regulatory networks. Adhesins include a family of surface proteins covalently attached to the peptidoglycan via a conserved LPXTG motif. Here we determined the protein and mRNA expression of LPXTG-proteins of S. aureus Newman in time-course experiments, and their relation to fibrinogen adherence in vitro. Experiments were performed with mutants in the global accessory-gene regulator (agr), surface protein A (Spa), and fibrinogen-binding protein A (ClfA), as well as during growth in iron-r

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Handel, R. "Evolution of ISDN towards broadband ISDN." IEEE Network 3, no. 1 (1989): 7–13. http://dx.doi.org/10.1109/65.20534.

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45

Tienhaara, Kyla. "Regulatory Chill in a Warming World: The Threat to Climate Policy Posed by Investor-State Dispute Settlement." Transnational Environmental Law 7, no. 2 (2017): 229–50. http://dx.doi.org/10.1017/s2047102517000309.

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AbstractThe system of investor-state dispute settlement (ISDS) found in over 3,000 bilateral investment treaties and numerous regional trade agreements has been criticized for interfering with the rights of sovereign states to regulate investment in the public interest, for example, to protect the environment and public health. This article argues that while much of the public debate around ISDS has focused on a small number of cases that have arisen over the regulation of tobacco packaging, there is a far greater threat posed by the potential use of ISDS by the fossil fuel industry to stall a

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Nasution, Nabilla Zelda. "Klausula Counter-claim dalam Bilateral Investment Treaty Indonesia." Jurist-Diction 2, no. 6 (2019): 2219. http://dx.doi.org/10.20473/jd.v2i6.15950.

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Investor-State Dispute Settlement (ISDS) merupakan suatu mekanisme penyelesaian sengketa antara investor dan negara penerima investasi (host state) karena suatu pelanggaran terhadap Hukum Investasi Internasional. Berdasarkan data UNCTAD, alasan yang sering diajukan dalam gugatan ISDS umumnya meliputi empat hal permasalahan yakni Most Favoured Nations, National Treatment, Non Exproriation, dan Fair and Equitable Treatment. Namun pengaturan penyelesaian sengketa investasi dengan mekanisme ISDS dianggap lebih berpihak kepada pihak investor dibandingkan kepada host state karena sebagian besar IIA

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Tam, G. S., G. S. Marks, J. F. Brien, and K. Nakatsu. "Sex- and species-related differences in the biotransformation of isosorbide dinitrate by various tissues of the rabbit and rat." Canadian Journal of Physiology and Pharmacology 65, no. 7 (1987): 1478–83. http://dx.doi.org/10.1139/y87-231.

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The biotransformation of isosorbide dinitrate (ISDN) by various tissues of the rabbit and rat was examined. Incubation of 2 × 10−7 M ISDN at 37 °C with tissue homogenates of liver, lung, kidney, intestine, skeletal muscle, aorta, and erythrocytes from the rabbit and rat resulted in a significant disappearance of ISDN after a 30-min incubation (also, 5-min incubation for liver). The disappearance of ISDN in each tissue homogenate was accompanied by an equimolar production of the mononitrate metabolites, isosorbide-2-mononitrate (2-ISMN) and isosorbide-5-mononitrate (5-ISMN), with the exception

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Raedler, Michael D., Samantha Heyne, Erica Wagner, et al. "Serologic Assay To Quantify Human Immunoglobulin G Antibodies to the Staphylococcus aureus Iron Surface Determinant B Antigen." Clinical and Vaccine Immunology 16, no. 5 (2009): 739–48. http://dx.doi.org/10.1128/cvi.00478-08.

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ABSTRACT A direct binding Luminex assay has been developed and validated for the detection of human immunoglobulin G (IgG) antibodies to the Staphylococcus aureus iron surface determinant B protein (IsdB) in serum following natural infection or immunization with investigational Saccharomyces cerevisiae-derived IsdB-based vaccines. To ensure that IsdB-specific IgG antibodies are measured following immunization with S. cerevisiae-derived IsdB, an Escherichia coli-produced IsdB antigen is used in the assay. The IsdB antigen is covalently conjugated to maleimide microspheres via an engineered carb

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HOVELJA, Tomaž, Olegas VASILECAS, and Damjan VAVPOTIČ. "EXPLORING THE INFLUENCES OF THE USE OF ELEMENTS COMPRISING INFORMATION SYSTEM DEVELOPMENT METHODOLOGIES ON STRATEGIC BUSINESS GOALS." Technological and Economic Development of Economy 21, no. 6 (2015): 885–98. http://dx.doi.org/10.3846/20294913.2015.1074130.

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As the competitive pressure of the global market for information systems (IS) continues to increase, IS development enterprises should start to consider if and how the use of IS development methodologies (ISDM) influences their main strategic business goals. More precisely, they should start to consider two different dimensions of the actual use of ISDM: the number of times an opportunity for ISDM use arises and the number of times the ISDM is actually used. Otherwise, they run the risk of mismanaging their ISDM-related investments. The goal of this study is to develop a model that would enabl

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Rimmer, Matthew. "The Chilling Effect: Investor-State Dispute Settlement, Graphic Health Warnings, the Plain Packaging of Tobacco Products, and the Trans-Pacific Partnership." Victoria University Law and Justice Journal 7, no. 1 (2018): 76–93. http://dx.doi.org/10.15209/vulj.v7i1.1044.

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Investor-State Dispute Settlement (ISDS) poses significant challenges in respect of tobacco control, public health, human rights, and sustainable development. Two landmark ISDS rulings provide procedural and substantive guidance on the interaction between ISDS and tobacco control. The ISDS action by Philip Morris against Uruguay in respect to graphic health warnings raised important procedural and substantive issues. The ISDS matter between Philip Morris and Australia over the plain packaging of tobacco products highlighted matters in respect of abuse of process. In the Trans-Pacific Partnersh

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