Log in

Relevant bibliographies by topics / ISDP / Journal articles

To see the other types of publications on this topic, follow the link: ISDP.

Journal articles on the topic 'ISDP'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'ISDP.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Zapotoczna, Marta, Simon Heilbronner, Pietro Speziale, and Timothy J. Foster. "Iron-Regulated Surface Determinant (Isd) Proteins of Staphylococcus lugdunensis." Journal of Bacteriology 194, no. 23 (2012): 6453–67. http://dx.doi.org/10.1128/jb.01195-12.

Full text

Abstract:

ABSTRACTStaphylococcus lugdunensisis the only coagulase-negativeStaphylococcusspecies with a locus encoding iron-regulated surface determinant (Isd) proteins. InStaphylococcus aureus, the Isd proteins capture heme from hemoglobin and transfer it across the wall to a membrane-bound transporter, which delivers it into the cytoplasm, where heme oxygenases release iron. The Isd proteins ofS. lugdunensisare expressed under iron-restricted conditions. We propose thatS. lugdunensisIsdB and IsdC proteins perform the same functions as those ofS. aureus.S. lugdunensisIsdB is the only hemoglobin receptor within theisdlocus. It specifically binds human hemoglobin with a dissociation constant (Kd) of 23 nM and transfers heme on IsdC. IsdB expression promotes bacterial growth in an iron-limited medium containing human hemoglobin but not mouse hemoglobin. This correlates with weak binding of IsdB to mouse hemoglobinin vitro. Unlike IsdB and IsdC, the proteins IsdJ and IsdK are not sorted to the cell wall inS. lugdunensis. In contrast, IsdJ expressed inS. aureusandLactococcus lactisis anchored to peptidoglycan, suggesting thatS. lugdunensissortases may differ in signal recognition or could be defective. IsdJ and IsdK are present in the culture supernatant, suggesting that they could acquire heme from the external milieu. The IsdA protein ofS. aureusprotects bacteria from bactericidal lipids due to its hydrophilic C-terminal domain. IsdJ has a similar region and protectedS. aureusandL. lactisas efficiently as IsdA but, possibly due to its location, was less effective in its natural host.

APA, Harvard, Vancouver, ISO, and other styles

2

Farrand, Allison J., Kathryn P. Haley, Nichole M. Lareau, et al. "An Iron-Regulated Autolysin Remodels the Cell Wall To Facilitate Heme Acquisition in Staphylococcus lugdunensis." Infection and Immunity 83, no. 9 (2015): 3578–89. http://dx.doi.org/10.1128/iai.00397-15.

Full text

Abstract:

Bacteria alter their cell surface in response to changing environments, including those encountered upon invasion of a host during infection. One alteration that occurs in several Gram-positive pathogens is the presentation of cell wall-anchored components of the iron-regulated surface determinant (Isd) system, which extracts heme from host hemoglobin to fulfill the bacterial requirement for iron.Staphylococcus lugdunensis, an opportunistic pathogen that causes infective endocarditis, encodes an Isd system. Unique among the known Isd systems,S. lugdunensiscontains a gene encoding a putative autolysin located adjacent to the Isd operon. To elucidate the function of this putative autolysin, here named IsdP, we investigated its contribution to Isd protein localization and hemoglobin-dependent iron acquisition.S. lugdunensisIsdP was found to be iron regulated and cotranscribed with the Isd operon. IsdP is a specialized peptidoglycan hydrolase that cleaves the stem peptide and pentaglycine crossbridge of the cell wall and alters processing and anchoring of a major Isd system component, IsdC. Perturbation of IsdC localization due toisdPinactivation results in a hemoglobin utilization growth defect. These studies establish IsdP as an autolysin that functions in heme acquisition and describe a role for IsdP in cell wall reorganization to accommodate nutrient uptake systems during infection.

APA, Harvard, Vancouver, ISO, and other styles

3

Buo-Oga, Samih, and Mohamed Nour. "A Proposed Quality Measurements for Information Systems Development Projects." International Journal of Computers and Informatics 3, no. 4 (2024): 40–52. http://dx.doi.org/10.59992/ijci.2024.v3n4p2.

Full text

Abstract:

The objective of this paper is to propose quality measurements for ISDP to achieve higher quality levels for information systems development projects (ISDP). The complexity of assessing information system quality stems from its many important dimensions. This paper presents important quality concepts and fundamentals related to ISDP. In addition, it presents the life cycle, phases, and activities of ISDP. Depending on the proposed steps and a combination of statistical techniques, this paper introduces a proposed quality assurance model for ISDP activities. This proposed model can be used for building a software tool for the quality assurance of ISDP.

APA, Harvard, Vancouver, ISO, and other styles

4

Li, Shupin, Noona Kiuru, Tuire Palonen, Katariina Salmela-Aro, and Kai Hakkarainen. "Peer selection and influence: Students’ interest-driven socio-digital participation and friendship networks." Frontline Learning Research 8, no. 4 (2020): 1–17. http://dx.doi.org/10.14786/flr.v8i4.457.

Full text

Abstract:

Digital technologies have been increasingly embedded in students’ everyday lives. Interest-driven socio-digital participation (ISDP) involves students’ pursuit of interests mediated by computers, social media, the internet, and mobile devices’ integrated systems. ISDP is likely to intertwine closely with young people’s social networks that has been scarcely studied quantitatively. To close this gap, the present paper investigated students’ peer selection and influence effects of the intensity of their ISDP and friendship networks. We collected two-wave data by administering a peer nomination to trace students’ friendship networks with peers and a self-reported questionnaire to examine students’ ISDP. Participants were 100 students in Finland (female: 53%; mean age = 13.48, in grade 7 in the first wave). Through stochastic actor-oriented modelling, the results showed that the students’ friendship ties with peers influenced the intensity of their ISDP practices to become more similar. Yet, students did not select peers as friends based on similar intensity levels of ISDP. Utilizing influence effect found in students’ ISDP and their peer networks, we suggest that connected learning (Ito et al., 2013) should be promoted to integrate students’ informal and formal learning in order to bridge the gap between students’ informal interest-related digital practices and formal educational practices.

APA, Harvard, Vancouver, ISO, and other styles

5

Rusydina, Rizka Mazaya, and Ahim Abdurahim. "Exploration of Success Factors for MSME Business Assistance (Study of Yogyakarta MSMEs Participating in the ISDP Program by BSI)." SHS Web of Conferences 201 (2024): 02004. http://dx.doi.org/10.1051/shsconf/202420102004.

Full text

Abstract:

This research aims to explore the factors that support the success of the 2022 ISDP MSME mentoring program, as well as efforts by the management of the 2022 ISDP MSME mentoring program to maintain the performance of MSMEs during and after the mentoring ends. The research method used is qualitative descriptive research to explore the factors that influencethe success of mentoring MSMEs. Data was obtained using interviews, observation, and documentation methods. Data analysis was carried out in four stages: relevance analysis, content analysis, correlation analysis, and triangulation. Informants were selected using purposive sampling and snowballing methods. Informants consisted of ISDP program managers and MSME mentoring participants. The research results show that the factors supporting the success of the “ISDP” MSME mentoring program consist of 4 factors: mentoring material that suits the needs of MSMEs, availability of mentoring funds or capital, routine monthly business assistance, and sustainability of MSME businesses. Apart from that, it was also found that efforts were made by the ISDP program to maintain the performance of MSMEs, namely by carrying out time management, building ukhuwah, and mapping participants.

APA, Harvard, Vancouver, ISO, and other styles

6

Bhattarai, Hem Lata. "Health Activities Under the Integrated Security and Development Programme (ISDP)." Medical Journal of Shree Birendra Hospital 5 (December 1, 2002): 56. http://dx.doi.org/10.3126/mjsbh.v5i0.21394.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Schmitt, David P. "Measuring sociosexuality across people and nations: Revisiting the strengths and weaknesses of cross-cultural sex research." Behavioral and Brain Sciences 28, no. 2 (2005): 297–304. http://dx.doi.org/10.1017/s0140525x05440054.

Full text

Abstract:

My response to the commentaries highlights three main points. First, the Sociosexual Orientation Inventory (SOI) has demonstrated adequate reliability and validity across dozens of studies, and it deserves its reputation as a useful measure of basic human mating strategies. Second, the sampling limitations of the International Sexuality Description Project (ISDP) do not negate the conclusion that sex differences in sociosexuality are likely universal across cultures. Third, the ISDP results support several theories of human sexuality, although some are based on faulty assumptions that render them less viable than others.

APA, Harvard, Vancouver, ISO, and other styles

8

Anisa, Muzaqi Dhiftania Luthfiya Azra Fajar Hidayatullah Nisa Azzahra Zariah Sakinah Siregar. "Implementasi Mudharabah Pada Pengembangan UMKM Wirausahaan Muda oleh BSI Maslahat Dalam Program Islamic Sociopreneur Development Program (ISDP)." Madani: Jurnal Ilmiah Multidisiplin 1, no. 6 (2023): 1031–38. https://doi.org/10.5281/zenodo.8175445.

Full text

Abstract:

<em>One of the main engines behind Indonesia's economic development is the growth of micro, small, and medium-sized businesses. However, there are still MSME actors who struggle with finding capital that occasionally is not sufficient to develop their businesses. This program may be one of the answers to their problems in doing so, as it offers mentors to help them in addition to financial assistance. This journal uses a qualitative research methodology. ISDP members are interviewed using qualitative research methodologies, and literature reviews examine reputable publications and materials. One of the sustainability initiatives developed by BSI and BSI Maslahat to serve as a venue for the distribution of community monies is the ISDP.</em>

APA, Harvard, Vancouver, ISO, and other styles

9

Chatard, Armand, Leila Selimbegović, and Paul N'Dri Konan. "Self‐esteem and suicide rates in 55 Nations." European Journal of Personality 23, no. 1 (2009): 19–32. http://dx.doi.org/10.1002/per.701.

Full text

Abstract:

Using recent data from the International Sexuality Description Project (ISDP), we examined whether national differences in self‐esteem across 55 nations are reflected in suicide rates. Results indicate that suicide is especially common in nations with relatively low levels of self‐esteem. This relation is consistent across sex lines, age of suicide and independent from several other relevant factors such as economic affluence, transition, individualism, subjective well‐being, and neuroticism. These findings provide support for the predictive validity of self‐esteem scores as assessed in the ISDP survey. They also contribute to a growing body of research documenting negative consequences associated with low self‐esteem. Possible implications for suicide prevention strategies are discussed. Copyright © 2008 John Wiley & Sons, Ltd.

APA, Harvard, Vancouver, ISO, and other styles

10

Torres, Victor J., Gleb Pishchany, Munir Humayun, Olaf Schneewind, and Eric P. Skaar. "Staphylococcus aureus IsdB Is a Hemoglobin Receptor Required for Heme Iron Utilization." Journal of Bacteriology 188, no. 24 (2006): 8421–29. http://dx.doi.org/10.1128/jb.01335-06.

Full text

Abstract:

ABSTRACT The pathogenesis of human infections caused by the gram-positive microbe Staphylococcus aureus has been previously shown to be reliant on the acquisition of iron from host hemoproteins. The iron-regulated surface determinant system (Isd) encodes a heme transport apparatus containing three cell wall-anchored proteins (IsdA, IsdB, and IsdH) that are exposed on the staphylococcal surface and hence have the potential to interact with human hemoproteins. Here we report that S. aureus can utilize the host hemoproteins hemoglobin and myoglobin, but not hemopexin, as iron sources for bacterial growth. We demonstrate that staphylococci capture hemoglobin on the bacterial surface via IsdB and that inactivation of isdB, but not isdA or isdH, significantly decreases hemoglobin binding to the staphylococcal cell wall and impairs the ability of S. aureus to utilize hemoglobin as an iron source. Stable-isotope-tracking experiments revealed removal of heme iron from hemoglobin and transport of this compound into staphylococci. Importantly, mutants lacking isdB, but not isdH, display a reduction in virulence in a murine model of abscess formation. Thus, IsdB-mediated scavenging of iron from hemoglobin represents an important virulence strategy for S. aureus replication in host tissues and for the establishment of persistent staphylococcal infections.

APA, Harvard, Vancouver, ISO, and other styles

11

Rios, Gloria P., and Sergio Botero. "An Integrated Indicator to Analyze Sustainability in Specialized Dairy Farms in Antioquia—Colombia." Sustainability 12, no. 22 (2020): 9595. http://dx.doi.org/10.3390/su12229595.

Full text

Abstract:

An integrated sustainability indicator in specialized dairy index (IISLE) is proposed for the evaluation of these production systems in four dimensions (financial, technical, social, and environmental). This index was validated in a study carried out with information from 18 dairy farms in Antioquia, a Colombian milk production region. The analytic hierarchy process (AHP) method was applied to prioritize criteria and sub-criteria. According to the proposed dimensions, four criteria were established (financial (ISDF), technical (ISDT), social (ISDS), and environmental (ISDA)) and 30 sub-criteria were analyzed. A multiple correlation analysis was performed to determine the intensity of the relationship among these four criteria and the overall index. The methodology includes a cluster analysis for the calculated IISLE. R software was used in the analysis. The proposed indicator is a powerful and useful planning and control tool for the evaluation of sustainability levels in dairy farms and is highly influenced by financial and technical criteria.

APA, Harvard, Vancouver, ISO, and other styles

12

Newson, Lesley, and Tom Postmes. "Less restricted mating, low contact with kin, and the role of culture." Behavioral and Brain Sciences 28, no. 2 (2005): 291–92. http://dx.doi.org/10.1017/s0140525x05380058.

Full text

Abstract:

On the basis of a reinterpretation of the International Sexuality Description Project (ISDP) data, we suggest that findings are consistent with the view that human reproductive behaviour is largely under social control. Behaviours associated with a high Sociosexual Orientation Index (SOI) may be part of a progressive change in reproductive behaviour initiated by the dispersal of kin that occurs as societies modernize.

APA, Harvard, Vancouver, ISO, and other styles

13

Stone, William C., and Andrew W. Taylor. "ISDP: Integrated Approach to Seismic Design of Reinforced Concrete Structures." Journal of Structural Engineering 120, no. 12 (1994): 3548–66. http://dx.doi.org/10.1061/(asce)0733-9445(1994)120:12(3548).

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Zhongwen Guo, Pengpeng Chen, Yuan Feng, Yongguo Jiang, and Feng Hong. "ISDP: Interactive Software Development Platform for Household Appliance Testing Industry." IEEE Transactions on Instrumentation and Measurement 59, no. 5 (2010): 1439–52. http://dx.doi.org/10.1109/tim.2010.2040931.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

&NA;. "XXIX Symposium of the ISDP - Graz, October 2-4, 2008." American Journal of Dermatopathology 30, no. 5 (2008): 514–33. http://dx.doi.org/10.1097/dad.0b013e31818c190a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Kiran, Shashi. "The trees are not the forest, and monogamy is certainly not a kind of wood." Behavioral and Brain Sciences 28, no. 2 (2005): 287–88. http://dx.doi.org/10.1017/s0140525x05340052.

Full text

Abstract:

The target article, which is part of a larger study, the International Sexuality Description Project (ISDP), seeks to explore cross-culturally aspects of human mating behavior on a global scale. However the nonrepresentation of large cultures restricts the depth of this study. The inferences drawn from such a sample must therefore remain limited despite the impressive sample sizes. In a larger context it raises thoughts on how partial disclosures may misrepresent the design of the larger study.

APA, Harvard, Vancouver, ISO, and other styles

17

Schmitt, David P. "Sociosexuality from Argentina to Zimbabwe: A 48-nation study of sex, culture, and strategies of human mating." Behavioral and Brain Sciences 28, no. 2 (2005): 247–75. http://dx.doi.org/10.1017/s0140525x05000051.

Full text

Abstract:

The Sociosexual Orientation Inventory (SOI; Simpson & Gangestad 1991) is a self-report measure of individual differences in human mating strategies. Low SOI scores signify that a person is sociosexually restricted, or follows a more monogamous mating strategy. High SOI scores indicate that an individual is unrestricted, or has a more promiscuous mating strategy. As part of the International Sexuality Description Project (ISDP), the SOI was translated from English into 25 additional languages and administered to a total sample of 14,059 people across 48 nations. Responses to the SOI were used to address four main issues. First, the psychometric properties of the SOI were examined in cross-cultural perspective. The SOI possessed adequate reliability and validity both within and across a diverse range of modern cultures. Second, theories concerning the systematic distribution of sociosexuality across cultures were evaluated. Both operational sex ratios and reproductively demanding environments related in evolutionary-predicted ways to national levels of sociosexuality. Third, sex differences in sociosexuality were generally large and demonstrated cross-cultural universality across the 48 nations of the ISDP, confirming several evolutionary theories of human mating. Fourth, sex differences in sociosexuality were significantly larger when reproductive environments were demanding but were reduced to more moderate levels in cultures with more political and economic gender equality. Implications for evolutionary and social role theories of human sexuality are discussed.

APA, Harvard, Vancouver, ISO, and other styles

18

Miajlovic, Helen, Marta Zapotoczna, Joan A. Geoghegan, Steven W. Kerrigan, Pietro Speziale, and Timothy J. Foster. "Direct interaction of iron-regulated surface determinant IsdB of Staphylococcus aureus with the GPIIb/IIIa receptor on platelets." Microbiology 156, no. 3 (2010): 920–28. http://dx.doi.org/10.1099/mic.0.036673-0.

Full text

Abstract:

The interaction of bacteria with platelets is implicated in the pathogenesis of endovascular infections, including infective endocarditis, of which Staphylococcus aureus is the leading cause. Several S. aureus surface proteins mediate aggregation of platelets by fibrinogen- or fibronectin-dependent processes, which also requires specific antibodies. In this study S. aureus was grown in iron-limited medium to mimic in vivo conditions in which iron is unavailable to pathogens. Under such conditions, a S. aureus mutant lacking the known platelet-activating surface proteins adhered directly to platelets in the absence of plasma proteins and triggered aggregation. Platelet adhesion and aggregation was prevented by inhibiting expression of iron-regulated surface determinant (Isd) proteins. Mutants defective in IsdB, but not IsdA or IsdH, were unable to adhere to or aggregate platelets. Antibodies to the platelet integrin GPIIb/IIIa inhibited platelet adhesion by IsdB-expressing strains, as did antagonists of GPIIb/IIIa. Surface plasmon resonance demonstrated that recombinant IsdB interacts directly with GPIIb/IIIa.

APA, Harvard, Vancouver, ISO, and other styles

19

Stricher, Romain, Paul Gond-Charton, Amrid Amnache, et al. "In Situ Doped Polysilicon (ISDP) Hydrophilic Direct Wafer Bonding for MEMS Applications." ECS Journal of Solid State Science and Technology 10, no. 6 (2021): 064010. http://dx.doi.org/10.1149/2162-8777/ac0b8f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Owen, JR, MP Campbell, MD Mott, et al. "IgG4-specific responses in patients with Staphylococcus aureus bone infections are not predictive of postoperative complications." European Cells and Materials 42 (September 22, 2021): 156–65. http://dx.doi.org/10.22203/ecm.v042a12.

Full text

Abstract:

The most prevalent pathogen in bone infections is Staphylococcus aureus; its incidence and severity are partially determined by host factors. Prior studies showed that anti-glucosaminidase (Gmd) antibodies are protective in animals, and 93.3 % of patients with culture-confirmed S. aureus osteomyelitis do not have anti-Gmd levels > 10 ng/mL in serum. Infection in patients with high anti-Gmd remains unexplained. Are anti-Gmd antibodies in osteomyelitis patients of the non-opsonising, non-complement-fixing IgG4 isotype? The relative amounts of IgG4 and total IgG against Gmd and 7 other S. aureus antigens: iron-surface determinants (Isd) IsdA, IsdB, and IsdH, amidase (Amd), α-haemolysin (Hla), chemotaxis inhibitory protein from S. aureus (CHIPS), and staphylococcal-complement inhibitor (SCIN) were determined in sera from healthy controls (Ctrl, n = 92), osteomyelitis patients whose surgical treatment resulted in infection control (IC, n = 95) or an adverse outcome (AD, n = 40), and post-mortem (PM, n = 7) blood samples from S. aureus septic-death patients. Anti-Gmd IgG4 levels were generally lower in infected patients compared to controls; however, levels among the infected were higher in AD than IC patients. Anti-IsdA, IsdB and IsdH IgG4 levels were increased in infected patients versus controls, and Jonckheere-Terpstra tests of levels revealed an increasing order of infection (Ctrl < IC < AD < PM) for anti-Isd IgG4 antibodies and a decreasing order of infection (Ctrl > IC > AD > PM) for anti-autolysin (Atl) IgG4 antibodies. Collectively, this does not support an immunosuppressive role of IgG4 in S. aureus osteomyelitis but is consistent with a paradigm of high anti-Isd and low anti-Atl responses in these patients.

APA, Harvard, Vancouver, ISO, and other styles

21

Peters, T. B., M. R. Poirier, and S. D. Fink. "Processing Macrobatch 2 at the Savannah River Site Integrated Salt Disposition Process (ISDP)." Separation Science and Technology 45, no. 12-13 (2010): 1801–6. http://dx.doi.org/10.1080/01496395.2010.494710.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Mikkelsen, Jakob H., Kasper Runager, and Christian B. F. Andersen. "The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus." Journal of Biological Chemistry 295, no. 7 (2019): 1781–91. http://dx.doi.org/10.1074/jbc.ra119.011612.

Full text

Abstract:

Iron is an essential nutrient for all living organisms. To acquire iron, many pathogens have developed elaborate systems to steal it from their hosts. The iron acquisition system in the opportunistic pathogen Staphylococcus aureus comprises nine proteins, called iron-regulated surface determinants (Isds). The Isd components enable S. aureus to extract heme from hemoglobin (Hb), transport it into the bacterial cytoplasm, and ultimately release iron from the porphyrin ring. IsdB and IsdH act as hemoglobin receptors and are known to actively extract heme from extracellular Hb. To limit microbial pathogenicity during infection, host organisms attempt to restrict the availability of nutrient metals at the host–pathogen interface. The human acute phase protein haptoglobin (Hp) protects the host from oxidative damage by clearing hemoglobin that has leaked from red blood cells and also restricts the availability of extracellular Hb-bound iron to invading pathogens. To investigate whether Hp serves an additional role in nutritional immunity through a direct inhibition of IsdH-mediated iron acquisition, here we measured heme extraction from the Hp–Hb complex by UV-visible spectroscopy and determined the crystal structure of the Hp–Hb–IsdH complex at 2.9 Å resolution. We found that Hp strongly inhibits IsdH-mediated heme extraction and that Hp binding prevents local unfolding of the Hb heme pocket, leaving IsdH unable to wrest the heme from Hb. Furthermore, we noted that the Hp–Hb binding appears to trap IsdH in an initial state before heme transfer. Our findings provide insights into Hp-mediated IsdH inhibition and the dynamics of IsdH-mediated heme extraction.

APA, Harvard, Vancouver, ISO, and other styles

23

Tiedemann, Michael T., Naomi Muryoi, David E. Heinrichs, and Martin J. Stillman. "Characterization of IsdH (NEAT domain 3) and IsdB (NEAT domain 2) in Staphylococcus aureus by magnetic circular dichroism spectroscopy and electrospray ionization mass spectrometry." Journal of Porphyrins and Phthalocyanines 13, no. 10 (2009): 1006–16. http://dx.doi.org/10.1142/s1088424609001352.

Full text

Abstract:

Absorption and magnetic circular dichroism (MCD) spectra, together with electrospray ionization mass spectral (ESI-MS) data are reported for the first two proteins in the Isd sequence of proteins in Staphylococcus aureus. IsdH-NEAT domain 3 (IsdH-N3) and IsdB-NEAT domain 2 (IsdB-N2) are considered to be involved in heme transport following heme scavenging from the hemoglobin of the host. The ESI-MS data show that a single heme binds to each of these NEAT domains. The charge states of the native proteins indicate that there is minimal change in conformation when heme binds to the heme-free native protein. Acid denaturation releases the bound heme and results in protein that exhibits significantly higher charge states, which we associate with unfolding of the protein structure. MCD spectra of the heme-bound native proteins show that the heme-iron is in a high-spin state, which is similar to that in IsdC-N. Addition of cyanide results in a spectral envelope characteristic of low-spin ferric hemes. The lack of complete binding for IsdH-N3 suggests that there is considerable congestion in the heme-binding site region. Unusually, reduction to the ferrous heme results in spectral characteristics of six coordination of the ferrous heme. CO is shown to bind strongly to both heme bound proteins, resulting in six-coordinate bound hemes. The spectra following reduction most closely resemble spectra recorded for heme with histidine in the fifth position and methionine in the sixth position. We report a theoretical model calculated from the X-ray structure coordinates of IsdH-N3, in which the heme is coordinated to nearby histidine and methionine. We propose that this structure accounts for the spectroscopic properties of the protein with the ferrous heme.

APA, Harvard, Vancouver, ISO, and other styles

24

Nakhaei, Mohammadreza, Azizollah Moraditalab, Atefe Mottaghianfar, and Davood Nodehi. "Comparison of the Passivity between CAD/CAM Implant Frameworks and Three Different Conventional Techniques Before and After Applying Veneering Porcelain." Avicenna Journal of Dental Research 15, no. 3 (2023): 103–8. http://dx.doi.org/10.34172/ajdr.1644.

Full text

Abstract:

Background: The passivity of the fit may be at risk during the casting as well as the firing of the veneering ceramic. In this study, the comparison of the passivity between computer-aided design/computer-assisted manufacturing (CAD/CAM) implant frameworks and three different conventional techniques before and after applying veneering porcelain was investigated. Methods: In this laboratory cross-sectional study, four groups (n=6) of 3-unit screw-retained implant-supported denture prostheses (ISDPs) were fabricated on a master model with 2 implants. The study groups were as follows: conventional casting with Ni-Cr alloy (group 1), casting with Ni-Cr alloy followed by sectioning and soldering the samples (group 2), double casting with Ni-Cr framework (group 3), and using CAD/CAM-fabricated framework (group 4). All frameworks received porcelain veneer. The one-screw test was performed before and after veneering to measure the vertical misfit at the abutment-framework interface using a stereomicroscope. The mean vertical misfit values were determined at the buccal, lingual, and proximal aspects. The data were analyzed using the Kruskal-Wallis and post hoc tests (α=0.05). Results: The accuracy of the fit varied significantly before and after veneering among the study groups (P<0.001). Frameworks prepared with CAD/CAM showed lower mean marginal misfit values compared to the other fabrication methods (P<0.001). Conclusions: Firing the veneering porcelain attached to a screw-retained ISDP may have an adverse effect on the accuracy of the fit. Soft non-pre-sintered CAD/CAM frameworks had better passivity compared to other three conventional methods applied.

APA, Harvard, Vancouver, ISO, and other styles

25

Liu, Zhenfang, Yang Zhou, Gordon Huang, and Bin Luo. "Risk Aversion Based Inexact Stochastic Dynamic Programming Approach for Water Resources Management Planning under Uncertainty." Sustainability 11, no. 24 (2019): 6926. http://dx.doi.org/10.3390/su11246926.

Full text

Abstract:

In this study, a dual interval robust stochastic dynamic programming (DIRSDP) method is developed for planning water resources management systems under uncertainty. As an extension of the existing interval stochastic dynamic programming (ISDP) method, DIRSDP can deal with two-stage stochastic programming (TSP)-based planning problems associated with dynamic features, input uncertainties, and multistage concerns. Compared with other optimization methods dealing with uncertainties, the developed DIRSDP method has advantages in addressing uncertainties with complex presentations and reflecting decision makers’ risk-aversion attitudes within its optimization process. Parameters in the DIRSDP model can be represented as probability distributions as well as single and/or dual intervals. Decision makers’ risk-aversion attitudes can be reflected through restricting the deviation of the recourse costs to a tolerance level. Water-allocation plans can then be developed based on the analysis of tradeoffs between the system benefit and solution robustness. The developed method is applied to a case of water resources management planning. The solutions are reasonable, indicating applicability of the developed methodology.

APA, Harvard, Vancouver, ISO, and other styles

26

Latifah, Eny, Fajriyatul Abadiyah, Rifatul Muawanah, and Diniyah Sukma. "Bank Syariah Indonesia dalam Menguatkan Ekonomi Sektor UMKM pada Masa Pandemi." Indonesian Journal of Islamic Economics and Finance 1, no. 2 (2022): 139–52. http://dx.doi.org/10.37680/ijief.v1i2.1151.

Full text

Abstract:

This study aims to find out the role of the Indonesian Islamic Bank merger in strengthening the economy in the MSME sector during the pandemic. The research method used is descriptive qualitative research with the type of library research, searching and recording data from various sources that are still related to the topic of the problem so that it becomes a unified whole to conclude. The results showed that the merger of Indonesian Sharia Banks had an important role in strengthening the economy in the MSME sector during the pandemic, namely BSI collaborated with LAZ Bangun Sejahtera Mitra Ummah to create an ISDP Program for entrepreneurial students in the form of providing UKT scholarships, coaching, mentoring, intensive and programmed training. In addition, BSI also collaborates with the well-known e-commerce platform Shopee in the Go Digital MSME program, which is expected by millennial entrepreneurs not only to make varied products at low prices but also to create the best quality brands and be able to take advantage of the development of digital technology for transformation business to the global market (go digital go international).

APA, Harvard, Vancouver, ISO, and other styles

27

Hurd, Alexander F., Jorge Garcia-Lara, Yvonne Rauter, Michaël Cartron, Ramlan Mohamed, and Simon J. Foster. "The iron-regulated surface proteins IsdA,IsdB, and IsdH are not required for heme iron utilization in Staphylococcus aureus." FEMS Microbiology Letters 329, no. 1 (2012): 93–100. http://dx.doi.org/10.1111/j.1574-6968.2012.02502.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Muromo, Francis, and Terence M. Mashingaidze. "Development-Induced Displacements and Livelihood Options — A Case of the Chingwizi Community in Mwenezi Rural District." Journal of Research in Social Science and Humanities 3, no. 6 (2024): 1–9. http://dx.doi.org/10.56397/jrssh.2024.06.01.

Full text

Abstract:

Using primary data of 100 households and literature review, this study examined the socio-economic opportunities or lack of them as well as vulnerabilities encountered by the Chingwizi Community in Mwenezi Rural District in Masvingo Province. The study argues that the Chingwizi people are rational, resourceful and strategic actors. It further contents that the relocated households were plunged into deeper socio-economic problems as the climatic and infrastructural conditions in the new area are harsher than where they were coming from. Primary data was collected from key informants through interviews, informal conversations and observation. Key informants included government officials from the ministries of local government, agriculture and land resettlement, community leadership (both traditional and elected), development workers from non-governmental organizations (NGOs) and the resettled farmers of Chingwizi in general. Literature review involved discussing empirical findings by other scholars on development-induced displacements (DIDs) in other parts of the world and Zimbabwe in particular. Findings from the study indicate that the state failed to fulfill its promises to the relocated households and that the principles of free, prior and informed consent (FPIC), fair and comprehensive compensation (FCC) as well as inclusive socio-economic development and profit-sharing (ISDP) were ignored by the state in the process of relocating households from Chivi and Masvingo rural areas. In light of the foregoing the study recommends the need to engage those communities affected by development projects so that sustainable options are arrived at.

APA, Harvard, Vancouver, ISO, and other styles

29

Paglialunga, Alberto, and Maurizio Siviero. "ISCP (ISDN Signalling Control Part): the Best Candidate for the Target Broadband-ISDN Signalling Protocol." European Transactions on Telecommunications 4, no. 2 (1993): 193–200. http://dx.doi.org/10.1002/ett.4460040215.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Tiedemann, Michael T., Tyler B. J. Pinter, and Martin J. Stillman. "Insight into blocking heme transfer by exploiting molecular interactions in the core Isd heme transporters IsdA-NEAT, IsdC-NEAT, and IsdE of Staphylococcus aureus." Metallomics 4, no. 8 (2012): 751. http://dx.doi.org/10.1039/c2mt20067h.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Pishchany, Gleb, Susan E. Dickey, and Eric P. Skaar. "Subcellular Localization of the Staphylococcus aureus Heme Iron Transport Components IsdA and IsdB." Infection and Immunity 77, no. 7 (2009): 2624–34. http://dx.doi.org/10.1128/iai.01531-08.

Full text

Abstract:

ABSTRACT Staphylococcus aureus is a human pathogen that represents a tremendous threat to global public health. An important aspect of S. aureus pathogenicity is the ability to acquire iron from its host during infection. In vertebrates, iron is sequestered predominantly within heme, the majority of which is bound by hemoglobin. To acquire iron, S. aureus binds hemoglobin, removes heme, and transports it into the cytoplasm, where heme is degraded. This process is carried out by the iron-regulated surface determinant system (Isd); however, the mechanism by which hemoglobin recognition occurs is not completely understood. Here we report that the surface receptor components of the Isd system, IsdA and IsdB, physically interact with each other and are anchored to a discrete location within the cell wall. This organized localization pattern is dependent upon the iron status of the bacterium. Furthermore, we have found that hemoglobin colocalizes with IsdB at discrete sites within the cell wall. Virulence studies revealed that IsdB is required for the efficient colonization of the heart and that IsdB is differentially expressed within infected organs, suggesting that S. aureus experiences various degrees of iron starvation depending on the site of infection. These findings significantly expand our understanding of hemoglobin iron acquisition and demonstrate an orchestrated pattern of regulation and localization for the S. aureus heme iron acquisition system.

APA, Harvard, Vancouver, ISO, and other styles

32

Skaar, Eric P., Andrew H. Gaspar, and Olaf Schneewind. "IsdG and IsdI, Heme-degrading Enzymes in the Cytoplasm ofStaphylococcus aureus." Journal of Biological Chemistry 279, no. 1 (2003): 436–43. http://dx.doi.org/10.1074/jbc.m307952200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Mack, John, Christie Vermeiren, David E. Heinrichs, and Martin J. Stillman. "In vivo heme scavenging by Staphylococcus aureus IsdC and IsdE proteins." Biochemical and Biophysical Research Communications 320, no. 3 (2004): 781–88. http://dx.doi.org/10.1016/j.bbrc.2004.06.025.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Lee, W. C., G. Ukpabi, M. L. Reniere, E. P. Skaar, and M. E. P. Murphy. "Ruffling of metalloporphyrins bound to IsdG and IsdI, two heme-degrading enzymes." Acta Crystallographica Section A Foundations of Crystallography 64, a1 (2008): C293. http://dx.doi.org/10.1107/s0108767308090648.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Pluym, Mark, Naomi Muryoi, David E. Heinrichs, and Martin J. Stillman. "Heme binding in the NEAT domains of IsdA and IsdC of Staphylococcus aureus." Journal of Inorganic Biochemistry 102, no. 3 (2008): 480–88. http://dx.doi.org/10.1016/j.jinorgbio.2007.11.011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Matsui, Toshitaka, Shusuke Nambu, Yukari Ono, Celia W. Goulding, Kouhei Tsumoto, and Masao Ikeda-Saito. "Heme Degradation by Staphylococcus aureus IsdG and IsdI Liberates Formaldehyde Rather Than Carbon Monoxide." Biochemistry 52, no. 18 (2013): 3025–27. http://dx.doi.org/10.1021/bi400382p.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Kim, Hwan Keun, Andrea DeDent, Alice G. Cheng, et al. "IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge." Vaccine 28, no. 38 (2010): 6382–92. http://dx.doi.org/10.1016/j.vaccine.2010.02.097.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Lee, Woo Cheol, Michelle L. Reniere, Eric P. Skaar, and Michael E. P. Murphy. "Ruffling of Metalloporphyrins Bound to IsdG and IsdI, Two Heme-degrading Enzymes inStaphylococcus aureus." Journal of Biological Chemistry 283, no. 45 (2008): 30957–63. http://dx.doi.org/10.1074/jbc.m709486200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Loutet, Slade A., Marek J. Kobylarz, Crystal H. T. Chau, and Michael E. P. Murphy. "IruO Is a Reductase for Heme Degradation by IsdI and IsdG Proteins inStaphylococcus aureus." Journal of Biological Chemistry 288, no. 36 (2013): 25749–59. http://dx.doi.org/10.1074/jbc.m113.470518.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Moriwaki, Yoshitaka, Tohru Terada, Jose Manuel Martinez Caaveiro, et al. "2I1412 Analysis of iron and other metalloporphyrins recognition and transport mechanism among IsdH, IsdA, IsdC from Staphylococcus aureus(Heme proteins 2,The 48th Annual Meeting of the Biophysical Society of Japan)." Seibutsu Butsuri 51, supplement (2011): S89. http://dx.doi.org/10.2142/biophys.51.s89_1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Conger, Matthew A., Deepika Pokhrel, and Matthew D. Liptak. "Tight binding of heme to Staphylococcus aureus IsdG and IsdI precludes design of a competitive inhibitor." Metallomics 9, no. 5 (2017): 556–63. http://dx.doi.org/10.1039/c7mt00035a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Handayani, Indri, Qurotul Aini, and Reza Alfiansah. "Fitur Form Emailer Dalam Memaksimalkan Penggunaan Rinfo Form Pada Perguruan Tinggi." Technomedia Journal 1, no. 1 (2016): 1–10. http://dx.doi.org/10.33050/tmj.v1i1.6.

Full text

Abstract:

Guna mempercepat pengisian ISAP dan Pemeriksaan ISAP, Perguruan Tinggi Raharja membutuhkan fitur yang dapat memonitoring perkuliahan, kehadiran dosen, dan kelengkapan silabus mata kuliah. Berdasarkan hasil penelitian pada ISAP iLearning Plus di Perguruan Tinggi Raharja belum ada sistem khusus yang berbasis online untuk memonitoring kehadiran dosen, maupun kesesuaian materi perkuliahan yang diberikan dengan Isian Satuan Acara Perkuliahan (ISAP) yang sudah di rencanakan. Dalam pengisian ISAP dosen masih datang ke koordinator iLearning Plus dan masih harus mengisi ISAP secara manual. Hal ini mengakibatkan proses pengisian ISAP dan memonitoring kehadiran menjadi tidak berjalan optimal. Oleh karena itu, rinfo form membantu memaksimalkan pengisian ISAP khususnya dosen iLearning Plus. Kata Kunci: isian satuan acara perkuliahan (ISAP), Rinfo form, monitoring In order to speed up charging and Inspection ISAP, Higher Education Prog requires features that can monitor the course , the presence of lecturers , and the completeness of the course syllabus. Based on the results of research on ISAP iLearning Plus in Higher Education Prog no special system for monitoring the presence of an online-based lecturer , as well as the suitability of the lecture material given by the Field Unit Class Events (ISAP), which has been planned. In charging ISAP lecturers still coming to Plus coordinator iLearning and still had to manually fill ISAP. This resulted in the charging process ISAP and monitoring presence into not running optimally. Therefore , rinfo form helps maximize charging ISAP especially lecturers iLearning Plus . Keywords: stuffing unit lecture event ( ISAP ) , Rinfo forms , monitoring

APA, Harvard, Vancouver, ISO, and other styles

43

Rauch, Sabine, Portia Gough, Hwan Keun Kim, Olaf Schneewind, and Dominique Missiakas. "Vaccine Protection of Leukopenic Mice against Staphylococcus aureus Bloodstream Infection." Infection and Immunity 82, no. 11 (2014): 4889–98. http://dx.doi.org/10.1128/iai.02328-14.

Full text

Abstract:

ABSTRACTThe risk forStaphylococcus aureusbloodstream infection (BSI) is increased in immunocompromised individuals, including patients with hematologic malignancy and/or chemotherapy. Due to the emergence of antibiotic-resistant strains, designated methicillin-resistantS. aureus(MRSA), staphylococcal BSI in cancer patients is associated with high mortality; however, neither a protective vaccine nor pathogen-specific immunotherapy is currently available. Here, we modeled staphylococcal BSI in leukopenic CD-1 mice that had been treated with cyclophosphamide, a drug for leukemia and lymphoma patients. Cyclophosphamide-treated mice were highly sensitive toS. aureusBSI and developed infectious lesions lacking immune cell infiltrates. Virulence factors ofS. aureusthat are key for disease establishment in immunocompetent hosts—α-hemolysin (Hla), iron-regulated surface determinants (IsdA and IsdB), coagulase (Coa), and von Willebrand factor binding protein (vWbp)—are dispensable for the pathogenesis of BSI in leukopenic mice. In contrast, sortase A mutants, which cannot assemble surface proteins, display delayed time to death and increased survival in this model. A vaccine with four surface antigens (ClfA, FnBPB, SdrD, and SpAKKAA), which was identified by genetic vaccinology using sortase A mutants, raised antigen-specific immune responses that protected leukopenic mice against staphylococcal BSI.

APA, Harvard, Vancouver, ISO, and other styles

44

Liu, Mengyao, Wesley N. Tanaka, Hui Zhu, Gang Xie, David M. Dooley, and Benfang Lei. "Direct Hemin Transfer from IsdA to IsdC in the Iron-regulated Surface Determinant (Isd) Heme Acquisition System ofStaphylococcus aureus." Journal of Biological Chemistry 283, no. 11 (2008): 6668–76. http://dx.doi.org/10.1074/jbc.m708372200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Pitcher, Joe. "ISDN." Telecommunications Policy 13, no. 4 (1989): 387–88. http://dx.doi.org/10.1016/0308-5961(89)90031-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Handel, R. "Evolution of ISDN towards broadband ISDN." IEEE Network 3, no. 1 (1989): 7–13. http://dx.doi.org/10.1109/65.20534.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

De Luca, Anna, Mark Feldman, Martins Paparinskis, and Catharine Titi. "Responding to Incorrect Decision-Making in Investor-State Dispute Settlement: Policy Options." Journal of World Investment & Trade 21, no. 2-3 (2020): 374–409. http://dx.doi.org/10.1163/22119000-12340176.

Full text

Abstract:

Abstract Criticism of the quality of investor-State dispute settlement (ISDS) decision-making often focuses on inconsistency (comparing ISDS decisions), and less frequently, incorrectness (evaluating individual ISDS decisions on a standalone basis). This article situates incorrect ISDS decision-making within the broader context of public international law and develops potential policy responses, guided by three considerations. First, criticism of ISDS decision-making has been significant. Second, criticism of particular ISDS decisions, even when widespread and intense, does not necessarily establish their incorrectness. Finally, development of policy options should be informed by a broad understanding of ‘incorrectness’, to include instances of questionable legal analysis that cast doubt on the reliability of ISDS legal conclusions and outcomes; that approach can support not only the avoidance of incorrect ISDS decision-making in a strict sense, but also, more expansively, the achievement of correct ISDS decision-making, consisting of two core elements: correct identification and precise application of applicable law.

APA, Harvard, Vancouver, ISO, and other styles

48

Ranjan, Prabhash. "Emerging Trends in Investor-State Dispute Settlement in New Free Trade Agreements." Global Trade and Customs Journal 17, Issue 7/8 (2022): 332–37. http://dx.doi.org/10.54648/gtcj2022046.

Full text

Abstract:

The Investor-State dispute settlement (ISDS) mechanism is going through a churning. Several countries, developed and developing, have started contesting the ISDS regime. This is reflected in the treaty practice of these countries. This article studies some of the recently signed free trade agreements (FTAs’) that contain an investment chapter to find out if there are broad discernible trends in the treaty practice of countries on ISDS reflected in these FTAs’. The article argues that there are three broad trends that one can decipher. First, some FTAs’ do not contain an ISDS provision. Second, some contain a limited ISDS provision. Third, the FTAs’ signed by the European Union shows a departure from the traditional ISDS mechanism toward an investor court system to settle international investment law disputes. These trends in FTAs’ on ISDS are part of the global practice that is not reposing the similar faith in ISDS as was the case in the last few decades. ISDS, FTAs’, investment treaties, RCEP, CPTPP, investor-State dispute settlement

APA, Harvard, Vancouver, ISO, and other styles

49

Jaloliddin, Rahmonov. "INVESTOR-STATE DISPUTE SETTLEMENT IN INTERNATIONAL PUBLIC LAW: AN EVALUATION OF RECENT DEVELOPMENTS." International Journal Of Law And Criminology 03, no. 04 (2023): 1–4. http://dx.doi.org/10.37547/ijlc/volume03issue04-01.

Full text

Abstract:

Investor-State Dispute Settlement (ISDS) is a mechanism for resolving disputes between investors and states under international investment agreements. While ISDS has become increasingly popular over the past few decades, it has also been subject to significant criticism for giving too much power to foreign investors and undermining the sovereignty of host states. In this article, we evaluate recent developments in ISDS from the perspective of international public law. We discuss the origins and growth of ISDS, as well as the increasing use of ISDS by investors from developed countries against developing countries. We then examine recent developments in ISDS, including the adoption of transparency rules by UNCITRAL, the Mauritius Convention on Transparency in ISDS, and changes to the way ISDS cases are decided. While these developments represent positive steps towards improving the legitimacy and effectiveness of ISDS, we also acknowledge remaining concerns regarding the imbalance of power between investors and host states, as well as the high costs of defending claims.

APA, Harvard, Vancouver, ISO, and other styles

50

Preez, Madely du. "ISAP: How does it make periodical information accessible?" Indexer: The International Journal of Indexing: Volume 23, Issue 2 23, no. 2 (2002): 74–77. http://dx.doi.org/10.3828/indexer.2002.23.2.7.

Full text

Abstract:

Examines the relevance of ISAP as an indexing database for the South African people by looking at who the ISAP indexers are, the ISAP indexing policy and the various formats in which ISAP is made available.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!