Dissertations / Theses on the topic 'Išemija'
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Gerulytė, Giedrė. "Inkstų išemijos/reperfuzijos poveikio mitochondrijų funkcijoms tyrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_215738-96119.
Full textThe aim of this work is to explore the effect of ischemia/reperfusion on rat kidney mitochondrial function. The main objectives of this work are to: 1) evaluate the effect of ischemia (20, 40, 60 minutes) in vitro on kidney mitochondrial function; 2) evaluate the effect of ischemia (60 minutes) and reperfusion (30 minutes) in vivo on kidney mitochondrial function; 2) explore the effect of ischemia/reperfusion on kidney mitochondrial respiratory chain complex I activity. We chose two experimental models of ischemia for investigation of its effects on rat kidney mitochondrial functions, i.e. in vitro and in vivo models. The mitochondria were isolated by a differential centrifugation method, while the protein was determined using biuret method. Mitochondrial respiration rate was measured polarographically. Complex I activity was evaluated spectrophotometrically. The results showed that mitochondrial damage become apparent very early - after 20 minutes, i.e. the maximal (ADP- stimulated) mitochondrial respiration rate decreased with both, glutamate/malate and succinate. It is obvious that by increasing the duration of ischemia, the mitochondrial damage increased. The damage of mitochondrial outer membrane increased by increasing the duration of ischemia. We found that both, ischemia (60 minutes) and reperfusion (30 minutes) decreased the mitochondrial State 3 respiration rate. 60 minutes ischemia/30 minutes reperfusion had no effect on mitochondrial inner membrane permeability... [to full text]
Škėmienė, Kristina. "Antocianinų poveikis širdies mitochondrijų funkcijoms ir išemijos sukeltai ląstelių žūčiai." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_233400-73337.
Full textA lot of research is carried out with anthocyanins, which are widely prevalent among colored berries, fruits, and vegetables and give them blue, red, violet, and purple colors. It is known that consumption of dietary plants and products rich in anthocyanins can reduce the risk of cardiovascular diseases. This protective effect is related to the antioxidant properties of anthocyanins. We have raised the hypothesis that anthocyanins could protect cardiomyocytes from ischemia/reperfusion-induced cell death reducing cytosolic cytochrome c. The aim of this work was to investigate the effect of anthocyanins on heart mitochondrial oxidative phosphorylation and determine what intracellular signaling pathways responsible for cell death are regulated by these compounds. The tasks of the study were: 1. To investigate the direct effect of anthocyanins on rat heart mitochondrial respiration rates; 2. To determine the ability of anthocyanins to reduce cytochrome c in vitro; 3. To determine whether anthocyanins – cytochrome c-reducing compounds – protect heart mitochondria from ischemia-induced mitochondrial dysfunction and ischemia/reperfusion-induced cardiomyocyte apoptosis and necrosis; 4. To examine whether anthocyanins with high cytochrome-c reducing activity can restore the efficiency of mitochondrial oxidative phosphorylation after ischemia; 5. To verify whether the effect of the investigated anthocyanins on cardiac mitochondrial function and their protective effect on... [to full text]
Velička, Linas. "Priešoperacinės magnetinio rezonanso angiografijos taikymas gydant cukriniu diabetu sergančiųjų kritinę kojų išemiją." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2005. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20051007_101030-95641.
Full textAbromaitis, Darius. "Storosios žarnos išemijos rizika ir prevencija pilvo aortos rekonstrukcijos operacijų metu." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2005. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20051111_105403-80052.
Full textBaranauskaitė, Agnė. "Kavos rūgšties fenetilo esterio poveikio inkstų mitochondrijoms tyrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_215632-14448.
Full textThe aim of investigation: to analyse the effect of caffeic acid phenethyl ester (CAPE) on kidney mitochodrial functions. Objectives: to evaluate direct in vitro effect of CAPE on kidney mitochondrial functions; the impact of CAPE on ischemia (20 min) in vitro affected kidney mitochondrial functions; on the mitochondrial respiratory chain complex I activity and on the mitochondria capability to accumulate Ca2+. Methods. Wistar rats were pretreated intraperitoneal with 22 mg/kg and 34 mg/kg of CAPE. Animals were divided into 4 groups: control group, 20 min of ischemia, CAPE 22 mg/kg group and CAPE 34 mg/kg group. Mitochondria were isolated by means of differential centrifugation. The mitochondrial respiration rate while oxidizing complex I and II dependent substrates was registered polarographically with Clark-type electrode. Ca2+ accumulation was measured fluorometrically. Activity of complex I was measured spectrophotometrically. Results: the results shown that CAPE 0,7 - 4,5 µM increases mitochondrial State 2 respiration rate by 15 - 34 % and has no effect on the State 3 respiration rate. Higher concentrations (5,2 - 6,5 µM) decreased mitochondrial State 3 respiration rate by 16% and 43%, respectively. Pretreatment with CAPE (22 mg/kg and 34 mg/kg) increased (by 20%) the ischemia suppressed mitochondrial State 3 respiration rate and respiratory control index. CAPE had no effect on succinate oxydation. Pretreatment with CAPE (22 mg/kg and 34 mg/kg) increased Ca2+... [to full text]
Pyragytė, Simona. "Sergančiųjų diabetu periferinės arterijų ligos rizikos veiksniai ir padariniai." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2012~D_20140704_172236-62581.
Full textObject of the research. 27–90 years old patients having the type 1 and type 2 diabetes mellitus and peripheral artery disease, who were treated at the Vilnius University Vascular Surgery Center in the Vilnius town University Hospital in the year 1997–2011. The aim of our research was. To analyse aspects of peripheral artery disease in patients with diabetes mellitus, who were cured at Vilnius University Vascular Surgery Center in the Vilnius town University Hospital as well as to determine the consequenses of PAD and the risk factors PAD. Material and methods of the research. 925 cases of the type 1 and type 2 diabetes mellitus were explored at the Vilnius University Vascular Surgery center in the Vilnius town University hospital in the year 1997–2011, who received treatment for the peripheral artery disease. The statistic survey has been done using the program pack SPSS 19.0 for Windows. Statistic importance level α=0.05. Results. Data about 378 women and 538 men have been explored. An average age of all the patients was 67.99±9.47 years. 95.6% of patients had the type 2 diabetes mellitus. An average duration of having disease was 12.95±9.91 years, 47.8% of cases had diabetic angiopathy, 34.9% of patients had nephropaty, 14.6% of cases had retinopathy, 33.7% of all the cases had polyneuropathy. According to the statistic importance rates retinopathy, nephropathy, polyneuropathy are more often among patients with the type 1 diabetes mellitus. Cardiovascular diseases were... [to full text]
Sabienė, Ingrida. "Išemine širdies liga sergančiųjų nerimastingumo ir pablogėjusios nuotaikos kitimai gydantis stacionare." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20090115_092704-03336.
Full textHeart and blood vessels diseases including ischemic heart diseases are considered a major issue of health care in the modern age as these are the diseases which are growing in numbers in the times of progress and increasing level of subsistence. The thesis explores some major psychological ischemic heart disease risk factors: anxiety, worsening mood and type A behaviour as well as health-favouring behaviour of ischemic heart disease patients, essentially concentrating upon ischemic heart disease patients’ anxiety and worsening mood and its alterations in the process of hospital treatment. The aim of this analysis is to explore alterations of ischemic heart disease patients’ anxiety and worsening mood at the time of hospital treatment. The analysis covered 178 individuals aged 28 to 74 (53.52±9.03) including 107 ischemic heart disease patients aged 29 to 74 (53.91±9.14) and 71 members of the control group aged 28 to 73 (52.94±8.89) who are not ischemic heart disease patients. In order to assess worsening mood and anxiety, A.S. Zigmond and R.P. Snaith’s Hospital Anxiety and Depression Scale was employed. The assessment of the activeness of behaviour was performed by the brief variant of Jenkins Activity Survey containing thirteen questions and 10 questions scale by Framingham for the identification of type A behaviour. Anxiety and worsening mood of ischemic heart disease patients treated in hospital improve in the final stages of hospital treatment. However, anxiety decreased... [to full text]
Vaičiūnaitė, Lina. "Ligonių, sergančių išemine širdies liga, pasitenkinimas ir paklusnumas naudojantis telemedicinos paslaugomis." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2007. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20070803.095926-15745.
Full textThe aim of this study was to evaluate patients and medics satisfaction and obedience using and rendering facilities of cardiology. The tasks: 1. To evaluate patients obedience using facilities of telemedicine. 2. To compare patients and medics satisfaction rendering cardiological system during clinical practice. 3. To evaluate patients satisfaction of treatment, rendering facilities of telemedicine. Methods of research: In the research were participated patients from Kaunas medicine university clinics Cardiology department, who had symptoms of coronary disease of heart and who was prescribed AKJO surgery. Patients were dispended to exploratory and share majority groups. Patients of exploratory group were using facilities of telemedicine, patients of share majority group weren’t. Cardiologists, who consulted patients, who were using facilities of telemedicine, participated too. Licert’s scale was used to compose questionnaire. Information was processed and analyzed using statistical pack SPSS 12.0 which analyses information. Hypothesis about independence of two features was verified using criterion mean p (p<=0,05) of Mann-Whitney U test. Results: Pilot study uncovered blind sides of newest technologies, which should be improved to render qualified facilities. Conclusion: Rendering facilities of telecardiology for patients with ischemic disease of heart were easy to fulfill all medics’ prescriptions accurate, 83 percent of respondents did not have any problems using gadget... [to full text]
Gintauskienė, Viltė Marija. "Sergančiųjų išemine širdies liga endokrininių veiksnių ryšys su subjektyviu sveikatos vertinimu." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2013~D_20131106_091127-78213.
Full textPsychosocial factors affect the occurrence of coronary artery disease (CAD) disease and development of complications. People with depression or anxiety symptoms have the activate hypothalamic-pituitary-adrenal axis. Thyroid hormone changes are also found in patients with CAD. Fatigue and health-related quality of life (HRQoL) depends not only on good physical health, but also on psychoemotional state, especially on the presence of depression and anxiety disorders. Therefore, it is important to evaluate complex of hormonal markers and behavioral factors (depression, anxiety and fatigue) interaction on patients with CAD for quality of life, disease course and outcome. The aim of this study was examine relationship of cortisol and thyroid axis hormones concentrations with NT-pro B type natriuretic peptide (NT-proBNP) concentrations and with patient oriented outcomes such as depressive symptoms, fatigue and HRQoL in CAD patients. Study demonstrates relationship between thyroid axis hormones and cortisol concentrations with depression, anxiety symptoms, fatigue and HRQoL in CAD patients. Low T3, free T4 and higher RT3 concentrations are associated with higher NT-proBNP levels, depression symptoms, higher fatigue and worse HRQoL. Higher morning cortisol concentrations are associated with depression symptoms in women. The data obtained can be used in patients with coronary artery disease and depressive anxiety disorder, disease progression, and prognosis and quality of life... [to full text]
Daukantaitė, Lina. "Sergančiųjų išemine širdies liga pacientų psichologinės – elgesio rizikos ypatumai stacionarinės reabilitacijos laikotarpiu." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2008. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20080828_133647-31984.
Full textThere are some factors, which are significant for ischemic heart disease development; their discrete influence is evidence – based, but it is important to ascertain if there are relationships among these factors. The purpose of the study is to evaluate ischemic heart disease patients‘ psychological – behavioral risk characteristics, during in - patients’ rehabilitation period. The subjects of this study were 204 ischemic heart disease patients from Abromiskes Rehabilitational Hospital, cardiological department (110 men, 94 women; mean age – 64,29m.). The demographical patients‘ indicators – age, gender, education, were gathered using a questionnaire. The data about ischemic heart disease form or other diagnosis, arterial blood pressure, overweight were taken from medical history. The attitude towards smoking, alcohol use also physical activity level, subjective health status was measured by using special questions. Stressogenic behavior was valuated by using Rosenman‘s behavior type‘s interview. The results of the study showed that men are more likely to use tobacco and alcohol, their physical activity level is higher, comparing with women. Younger women were more likely to use alcohol, comparing with older women. Younger men were more physically active, comparing with older men. Patients with higher education were more physically active, comparing with patients with lower education. Ischemic heart disease form and arterial blood pressure were not related with tobacco or... [to full text]
Zavadskaja, Violeta. "Smulkiosios motorikos atsigavimas pirminės reabilitacijos etape pacientams, patyrusiems išeminį galvos smegenų insultą." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120621_112815-19266.
Full textStudy subject: the dynamis of interchange of fine motor and functional independence in the process of the initial rehabilitation. The problem of the study: the rehabilitation of each patient suffering from stroke has different requirements, however, to this date literature does not indicate defined individualisation types of stratification and rehabilitation programmes, assigned to recover the control of stroke affected hand/arm movement (Meldrum, 2004). In order to effectively use rehabilitation resources, it is important to foresee the possible consequences of the disease (Milinavičienė ir kt., 2007). Therefore we analysed the fine motor recovery at the initial rehabilitation stage in the patients who had suffered ischemic head brain stroke. Study aim: to analyse and evaluate patients‘, who had suffered ischemic head brain stroke, the small motor post stroke recovery as well as the change in functional independence in the initial rehabilitation stage. Study goals: 1. To examine and name the dominant fine motor recovery in the initial rehabilitation stage; 2. to examine and evaluate change in patients‘ functional independence in the initial rehabilitation stage; Hypothesis: at the initial rehabilitation stage the short-term and long-term physio-therapeutic goals have to match a patient‘s regenerative potential, which can also be evaluated with reference to the initial functional stage at a patient‘s arrival to hospital. Study methods: Barthel test measuring a patient‘s... [to full text]
Intaitė, Gintarė. "Relaksacijos taikymas arterinio kraujo spaudimo reguliavimui sergančiųjų išemine širdies liga stacionarinės reabilitacijos etape." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2008. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20080828_135113-12189.
Full textIt is still unclear if effectiveness of PMR is related with age, gender, education, IHD form, subjective health status, subjective tension and muscle tension for ischemic heart disease patients. So the aim of this survey is to analize how effectiveness of progressive muscle relaxation in blood pressure regulation is related with these factors for ischemic heart disease in-patients at their rehabilitation period. 204 patients from Abromiškės rehabilitation hospital, cardiac department were invited to participate in relaxation groups, but in the first group participated only 53 (48,18%) men and 40 (42,55%) women, in the second - 20 (18,18%) men and 14 (14,89%) women, in the third - 15 (13,63%) men and 12 (12,76%) women and in fourth - 12 (10,9%) men and 8 (8,51%) women. Participants attended in four hourly relaxation groups which were four times per week. With the purpose to evaluate PMR effectiveness for blood pressure regulation and its’ relation with factors, participants were given questionnaires also relaxation groups were provided. At the beginning and at the end of each session blood pressure was measured also muscle tension was evaluated with the given model and 10 score scale was given for subjective feeling evaluation. The results of this study showed that the statistically significant reductions of blood pressure were only for men also for younger patients and patients with higher education, for patients with easier IHD form and for patients with worse... [to full text]
Staniūtė, Margarita. "Sergančiųjų išemine širdies liga su sveikata susijusi gyvenimo kokybė ir jos pokyčiai ilgalaikio stebėjimo metu." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2007. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20070803.100716-87171.
Full textCardiovascular diseases including coronary artery disease (CAD) are very prevalent in Lithuania. The primary outcome interest has traditionally been mortality, but patients and researchers are increasingly interest in identifying interventions that not only improve mortality, but also reduce symptoms, increase functional ability; in other words, improve patients health-related quality of life. Health-related quality of life represents the effect of an illness and its treatment as perceived by the patient, that it is modified by impairments, functional stress, perceptions and social opportunities, and is influenced by disease, injury, treatment or policy. The aim of the study was to analyze health-related quality of life in CAD patients and to assess its changes during long-term period. The objectives of the study: 1. To evaluate health-related quality of life in CAD patients according to sociodemographic factors (gander, age, education level and employment status). 2. To evaluate health-related quality of life in CAD patients according to functional status ���� angina pectoris, heart failure, NYHA functional class, anxiety, depression and sleep quality. 3. To assess the impact of demographic factors, cardiovascular status, psycho-emotional status and sleep quality on health-related quality of life in CAD patients. 4. To assess the health-related quality of life changes during long-term period in CAD patients (after acute myocardial infarction (MI), percutaneous transluminal... [to full text]
Raugelienė, Rūta. "Sergančiųjų išemine širdies liga kairiojo skilvelio funkcijos ir morfometrijos pokyčiai po kairiojo skilvelio tūrio mažinimo operacijų." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20061017_095309-15658.
Full textLukšienė, Dalia. "Metabolinio sindromo korekcijos poreikio įvertinimas priklausomai nuo jo ryšio su išemine širdies liga ir prevencijos modelio pasiūlymas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060606_101209-74408.
Full textLiutkus, Danius. "Sergančiųjų išemine galvos smegenų liga atrankos kriterijų smegenų revaskuliarizacijai patikslinimas ir veiksnių, įtakojančių ligonių pooperacinį išgyvenamumą, nustatymas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20061204_145800-64779.
Full textAndruškienė, Jurgita. "Nusiskundimai miegu, jų sąsajos su išemine širdies liga, arterine hipertenzija, depresine nuotaika ir su sveikata susijusia gyvenimo kokybe." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20060125_115004-68068.
Full textČerniauskaitė, Rūta. "Sergančių išemine širdies liga asmenų emocijų ir arterinio kraujo spaudimo kitimai taikant ekspresyvaus rašymo metodą psichosocialinės reabilitacijos metu." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130603_143647-86343.
Full textThe aim of research – to determine the changes of emotions and arterial blood pressure of the patients with ischemic heart disease by applying the method of expressive writing during psychosocial rehabilitation. 164 patients of cardiology department participated in the survey. 126 patients ( 58 men and 68 women) completed the course of four session. The patients attended four 30 min meetings four days in a row. The goal was to evaluate the efficiency of expressive writing for the changes of emotions and arterial blood pressure. The patients were divided into three groups: a) a group of expressive writing, the participants of which wrote their experiences related to the disease b) neutral writing group, where the participants wrote about everyday activities; c) control group. At the beginning and at the end of each meeting their blood pressure was measured. The participants had to evaluate their emotional state during the first and the last meetings. The survey results showed that the change of negative emotions was higher in the participants of expressive writing than in the groups of neutral or control. The changes of „happiness“ were higher in expressive writing group than in control group. Other positive emotions did not differentiate among the groups. The changes of systolic blood pressure in expressive writing group were not higher than in the neutral group, but higher in comparison with control group. The changes of diastolic blood pressure did not differ among the... [to full text]
Titova, Anželika. "Pacientų, sergančių ūminiu koronariniu sindromu, širdies nepakankamumo įtaka gyvenimo kokybei." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20140626_184817-21262.
Full textKeywords: coronary heart disease, acute coronary syndrome, heart failure, quality of life. Purpose of the research: to appraise the influence of heart failure on the quality of life of patients with acute coronary syndrome. Objectives of the research: to determine how separate symptoms of heart failure (weakness or dyspnea, anxiety or depression), the frequency of repetition and the severity of symptoms affect the quality of life of patients differing from the point of view of the functional class of heart failure. To compare the ability to cope with everyday living tasks by patients differing in terms of the functional class of heart failure. To determine how the severity of heart failure influences the quality of life in patients with acute coronary syndrome. To check patients' knowledge about the relevant illness. To offer practical recommendations for the efficient application of life quality survey questionnaires in everyday practice of each patient with of heart failure for the purpose of improving the quality of life of patients. Population under the research: 109 patiens with acute coronary sindrome and heart failure receiving medical treatment at Vilnius University Hospital Santariškių Clinics. Methods of the research. Research consisted of a questionnaire-based survey carried out on the grounds of Minnesota Living With Heart failure and Kansas City Cardiomyopathy questionnaires as well as of the analysis of medical records and test results. Statistical anglysis was... [to full text]
Stanislovaitienė, Daiva. "Klinikinių veiksnių, oksidacinio streso žymens N-karboksi(metil)lizino ir SCARB1 geno polimorfizmo sąsajos su amžine geltonosios dėmės degeneracija ir išemine širdies liga." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2013~D_20140106_083847-47174.
Full textAge-related macular degeneration (ARMD) is the commonest cause of blindness among persons over the age of 50 and its prevalence is likely to increase as a consequence of population ageing. ARMD is a disorder of unknown cause and pathogenesis, therefore current options for ARMD prevention and treatment are limited. In the recent study the associations between ARMD and CAD, according the angiographic findings of atherosclerosis in the coronary arteries, were analyzed. The oxidative stress impact and clinical factors determining susceptibility to ARMD and CADath+, separately and common susceptibility factors for both diseases prediction were ascertained. Analysis of novel genetic biomarker, the rs5888 variant of SCARB1 gene, identified the „protective“ SCARB1 rs5888 TT genotype, associated with the lower risk of ARMD and CADath+, and a „risk-determining“ CT genotype, determining higher ARMD+CADath+ risk. The evaluation of macular lesion area by using the methods of mathematical morphology revealed that in late stage ARMD subjects carriers of SCARB1 rs5888 CT genotype the area of macular lesion was larger than in TT genotype carriers. New information about ARMD and CAD discovered additional knowledge about ARMD etiopathogenesis and might be helpfull in search of new treatments or strategies for ARMD prevention. Evaluation of macular lesion area by mathematical morphology methods used in this study may be useful in ophthalmological practice to monitor the dynamics of ARMD.
Stroputė, Dalia. "Association between weather and well-being of patients with coronary artery disease." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140711_091353-69865.
Full textMoksliniai tyrimai rodo, kad egzistuoja sąveika tarp orų pokyčių ir žmonių sveikatos ir ši sąveika sudaro labai platų spektrą – nuo subjektyvios savijautos pablogėjimo iki mirties. Dėl reakcijų į orų pokyčius, žmonės gali būti suskirstyti į dvi grupes – jautrius orų pokyčiams ir atsparius. Tačiau standartizuotų instrumentų, kurie leistų įvertinti jautrumą orams ir atskirti jautrius orų pokyčiams asmenis, ypač skirtingų susirgimų grupėse, trūksta. Sergantieji širdies ligomis ir asmenys išgyvenantys psichologinį distresą priskiriami prie vienų iš jautriausių orų pokyčiams. Įrodyta, kad tiek psichologinis distresas, tiek asmenybės D tipas yra susiję su išeminės širdies ligos išsivystymu ir progresavimu. Be to, pastaraisiais metais keliamos hipotezės, kad individualūs skirtumai, tokie kaip asmenybės bruožai, taip pat gali įtakoti jautrumą orams. Darbo tikslas buvo išnagrinėti ir įvertinti sergančiųjų išemine širdies liga subjektyvios savijautos sąsajas su orais ir jos ryšį su asmenybės bruožais, nerimo ir depresijos simptomais. Darbo uždaviniai: 1) validizuoti tyrime naudojamą instrumentą asmenybės D tipui vertinti; 2) sukurti savikontrolės dienyną jautrumui orams įvertinti ir atlikti jo psichometrinę analizę; 3) nustatyti sąsajas tarp sergančiųjų išemine širdies liga subjektyvios savijautos ir orų, 4) įvertinti sergančiųjų išemine širdies liga subjektyvios orų sąlygotos savijautos sąsajas su nerimu, depresija ir asmenybės bruožais.
Zuozienė, Gitana. "Miokardo revaskuliarizacijos, taikant smūginės bangos Evaluation of myocardium revascularisation by cardiac shock-wave therapy applying multimodal image analysis." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20131004_095205-44921.
Full textMSBT– tai naujas atkuriamojo/ regeneracinio gydymo būdas, galintis tapti revaskuliarizacijos alternatyva, nes kamieninių ląstelių pritaikymas tokiais tikslais tebėra tiriamas. MSBT metu naudojamos žemo dažnio mechaninės bangos, kurioms veikiant, pagerinama širdies perfuzija ir sukuriamas kraujagyslių tinklas. Tokios bangos pirmą kartą medicinoje buvo pritaikytos inkstų akmenims skaldyti maždaug prieš 20 metų . MSBT tyrimai pradėti atlikti su pacientais, kuriems diagnozuota labai pažengusi išeminė širdies liga, lydima III−IV klasės krūtinės anginos(KA) pagal Kanados klasifikaciją (CCS), yra trijų vainikinių arterijų liga, kartais su kairės vainikinės arterijos kamieno stenoze. Šiems pacientams anksčiau atliktos angioplastikos ir stentavimo procedūros arba viena ar kelios aortokoronarinių jungčių suformavimo operacijos, tačiau KA atsinaujino, todėl nuolatos skiriamos maksimalios toleruojamos nitratų dozės. Tačiau krūtinės anginos epizodai kartojasi kelis kartus per dieną minimalaus fizinio krūvio metu ar net ramybėje. Pasaulyje šis gydymo metodas tik pradedamas taikyti ir pirminės patirties sukaupta tik nedaugelyje klinikų. Iki 2008m. VUL Santariškių klinikose išemine širdies liga (IŠL) sergantys pacientai buvo gydomi standartiniais metodais: medikamentais, PKI ir vainikinių arterijų apeinamųjų jungčių suformavimo operacija. 2008 m. Vilniaus universiteto ligoninės Santariškių klinikose labai pažengusia išemine širdies liga sergančių pacientų gydymui, be medikamentinio ir... [toliau žr. visą tekstą]
Zuozienė, Gitana. "Miokardo revaskuliarizacijos, taikant smūginės bangos terapiją, efektyvumo vertinimas daugialypės (multimodalios) vaizdinės diagnostikos metodais." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20131004_095219-57588.
Full textIschemic heart disease (IHD) is one of leading morbidity and mortality caused worldwide. Along with medical treatment currently there are two main methods of coronary revascularisation – percutaneous coronary intervention (PCI) and aortocoronary bypass surgery (ACBS). New heart revascularisation methods are under development, which are to be applied for routine practice in the future. One of methods stimulating angiogenesis is cardiac shock wave therapy (CSWT). CSWT is new reconstructive / regeneration treatment method offering alternative for revascularisation, as use of steam cells for such purposes is still in the stage of trials. Low frequency mechanical waves are used for CSWT. Their effect results in improved heart perfusion and development of blood vessels' network. Such waves for the first time in medicine were applied about 20 years ago for renal stones fragmentation. This treatment method has been recently applied in clinics worldwide and only few of them obtained some experience in this area. CSWT, along with medical and invasive treatment methods for patients with severely advanced ischemic heart disease, in Santariškių Clinics of Vilnius University Hospital was introduced in 2008.
Mačys, Antanas. "Miokardo perfuzijos ir kontrakcinės funkcijos įvertinimas radionuklidinės kompiuterinės tomografijos metodu bei prognozė po chirurginės revaskulizacijos." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2005. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20050905_152622-83820.
Full textLiutkevičienė, Rasa. "Amžinės geltonosios dėmės degeneracijos ir išeminės širdies ligos sąsajos su matrikso metaloproteinazių genų polimorfizmu." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111220_141337-60930.
Full textThe goals were as follows: 1. To determine the prevalence of AMD in patients with IHD and compare with the prevalence in a random sample of Kaunas population (at 40-64 yrs old). 2. To compare the main clinical characteristics of the patients exhibiting early AMD and IHD together with the patients with IHD alone. 3. To determine the frequency of the genotypes of the matrix metalloproteinases (MMP-2 (-735 C/T), MMP-2 (-1306 C/T), MMP-3 (-1171 5A/6A), MMP-9 (-1562 C/T)), and genotype combinations that have an influence on the development of early AMD. 4. To determine the frequency of the genotypes of the matrix metallo¬proteinases (MMP-2 (-735 C/T), MMP-2 (-1306 C/T), MMP-3 (-1171 5A/6A), MMP-9 (-1562 C/T)), in early AMD patients with soft or hard drusen. 5. To determine the frequency of the genotypes of the matrix metallo¬proteinases (MMP-2 (-735 C/T), MMP-2 (-1306 C/T), MMP-3 (-1171 5A/6A), MMP-9 (-1562 C/T)), and the influence of genotype combi¬na¬tions on the development of AMD and IHD together, and only on IHD development. 6. To determine the results of functional acuity contrast sensitivity test in patients with early mild and early intermediate AMD, and color contrast sensitivity in patients with AMD, and in ophthalmologically healthy patients.
Vaišnoraitė, Lina. "Miofascijinių trigerinių taškų terapijos ir tempimo pratimų poveikis skausmui ir kaklo judesių amplitudei." Bachelor's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130910_100535-13590.
Full textProblem of study: Myofascial pain syndrome, caused by active myofascial trigger points, causes chronic muscle pain, restricts range of motion, decreases sleep and quality of life. Latent myofascial trigger points at any time can transforme into active myofascial trigger points, when a mechanical stimulus appears. Treating and eliminating latent myofascial trigger points prevent latent myofascial trigger points from transforming into active myofascial trigger points, and hence, prevent the development of myofascial pain syndrome. Object of study: changes of cervical range of motion and myofascial trigger points pain after application of myofascial trigger point therapy and streching exercises. Aim of study: to determine the impact of myofascial trigger point therapy and streching exercises for MTrPs pain and cervical range of motion. Goals of study: 1. To determine the change of sternocleidomastoid and upper trapezius muscles myofascial trigger points pain and cervical range of motion, when ischemic compression is applied. 2. To determine the change of sternocleidomastoid and upper trapezius muscles myofascial trigger points pain and cervical range of motion, when ischemic compression and streching exercises are applied. 3. To compare the effectiveness of ischemic compression and streching exercises on sternocleidomastoid and upper trapezius muscles myofascial trigger points pain and cervical range of motion. 4. To determine the relation beatween myofascial trigger points pain... [to full text]
Gintauskienė, Viltė Marija. "Endocrine factors and patient centered outcomes in coronary artery disease." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130919_143951-09330.
Full textPsichosocialiniai veiksniai turi įtakos išeminės širdies ligos (IŠL) vystymuisi ir komplikacijų atsiradimui. Depresijos ir nerimo patogenezėje dalyvauja pagumburio-hipofizės-antinksčių ašis. Skydliaukės hormonų pokyčiai taip pat dažnai randami sergantiesiems IŠL bei depresija. Nuovargis ir su sveikata susijusi gyvenimo kokybė priklauso ne tik nuo geros fizinės sveikatos, bet ir nuo psichoemocinės būklės, todėl svarbu kompleksiškai įvertinti hormoninių žymenų ir elgesio veiksnių (depresijos, nerimo ir nuovargio) sąveikos įtaką sergančiųjų IŠL gyvenimo kokybei, ligos eigai bei baigtims. Šio tyrimo tikslas buvo išnagrinėti kortizolio ir skydliaukės ašies hormonų koncentracijų ryšį sergantiesiems IŠL su N-galinio smegenų tipo natriuretinio propeptido (NT-proBNP) koncentracija bei subjektyviomis sveikatos būklėmis: depresijos, nerimo simptomais, nuovargiu ir su sveikata susijusia gyvenimo kokybe. Tyrimas parodė skydliaukės hormonų ir kortizolio koncentracijų reikšmingą ryšį su subjektyviu sveikatos vertinimu sergantiesiems IŠL. Mažesnė bendrojo T3, laisvojo T4 ir didesnė reversinio T3 koncentracija susijusi su didesne NT-proBNP koncentracija, depresijos simptomų pasireiškimu, didesniu nuovargiu ir blogesniu su sveikata susijusios gyvenimo kokybės vertinimu. Didesnė rytinio kortizolio koncentracija susijusi su depresijos simptomų pasireiškimu moterims. Gauti duomenys gali būti panaudoti sergančiųjų IŠL depresijos bei nerimo simptomams, ligos eigai, prognozei ir gyvenimo kokybei... [toliau žr. visą tekstą]
Volodkaitė, Aušra. "Koronarine širdies liga sergančių pacientų sveikatos priežiūros ir slaugos poreikiai." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20140623_180432-43359.
Full textFollowing the information by the World Health Organization (WHO) CHD is the leading cause of disability and early death all over the world. Modification of risk factors may reduce the number of clinical records and early deaths. Prevention measures need to be taken for individuals with already diagnosed CHD as well as those with risk factors for CHD. Thesis objective: Investigation of healthcare and nursing needs of patients after CHD. Thesis tasks: Assessment of risk factors affecting patients suffering from CHD and knowledge possessed by patients suffering from CHD about the need for modification of the risk factors; Examination of biopsychoemotional condition of patients suffering from CHD; Analysis of physical activity of patients suffering from CHD; Examination of health condition–related quality of life of patients suffering from CHD; Suggesting possible methods of nursing staff working with the patients aiming at CHD prevention. Material and methodology: Investigation target: Knowledge possessed by patients suffering from CHD; healthcare and nursing needs. Investigation method: interviewed patients suffering from CHD through applying standardized questionnaires; analysis of case records, measurements of physical data of patients. Questionnaires used: Questionnaire developed by the European Society of Cardiology, aimed to assess the level of knowledge on prophylaxis of CHD EU-wide; HADS Questionnaire – Hospital Anxiety and Depression scale; EUROQOL 5D Questionnaire... [to full text]