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Herlihy, Shaun Lawrence. "Factors influencing the efficiency of photoinitiation in radiation curable ink formations." Thesis, University of Kent, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360974.
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In an effort to be able to use photoinitiators to their maximum potential, the sequence of events that occurs in an ink formulation during the UV curing process has have been studied and information presented to allow more effective formulation. Emphasis has been placed on highlighting the variables that have the greatest impact both on photoinitiator efficiency and on the suitability of individual photoinitiators and synergists for use in particular applications. These variables were found to be photoinitiator thermal stability, UV light utilisation, reaction mechanisms and cure reactivity. A wide range of photoinitiators and synergists were investigated using thermogravimetric analysis (TGA) and thermogravimetric analysis-mass spectroscopy (TGA-MS) to define both their thermal stability and whether under heating they thermally decompose or merely evaporate. Differential photocalorimetry (DPC) was used to determine which wavelengths from a typical medium pressure mercury curing lamp are the most important for providing cure, with both theoretical and practical methods being used to define the extent to which these wavelengths penetrate into pigmented and non-pigmented coatings. A procedure was devised and validated for this purpose. The reaction mechanism and photodecomposition products of a range of photoinitiators were investigated using gas chromatography-mass spectroscopy (GC-MS) and radical trapping experiments. The reaction mechanisms are discussed in terms of available literature knowledge. Evidence is also presented suggesting that, with only particular exceptions, cleavage photoinitiators can also react by a hydrogen abstraction mechanism in the presence of an amine synergist. A real time infrared spectrometer (RTIR) was set up and a method validated for following the UV curing reaction through changes in the acrylate double bond concentration. The advantages and disadvantages of this instrument are discussed in terms of other similar instruments reported in the literature, and the technique subsequently used to measure the reaction rates of a wide range of photoinitiators. Other factors such as photoinitiator concentration, amine synergist type I level and formulation viscosity were also investigated to determine their influence on the cure process.
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Ea, Chee-Kwee. "Ubiquitination-dependent activation of IKK." Access to abstract only; dissertation is embargoed until after 12/20/2006, 2005. http://www4.utsouthwestern.edu/library/ETD/etdDetails.cfm?etdID=125.
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Ang, Choon Jek, and choonjej@yahoo com au. "Treatment of printing ink wastewater using high liquid carryover mode function." Swinburne University of Technology. Environment and Biotechnology Centre, 2005. http://adt.lib.swin.edu.au./public/adt-VSWT20051017.115207.
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The aim of this project is to investigate the feasibility of the use of a novel process of high liquid carryover (HLC) mode flotation to treat wastewater from a cardboard printing and coating plant. This is conducted by characterising the process conditions with the purpose of achieving a set condition that have a low susceptibility to variability in the wastewater composition. Information pertaining to the surface and physical characteristics of the solid contained in the wastewater sample were used to explain the flotation outcomes. Fe(II) was found to be more suited for industrial use as coagulant over the more commonly known coagulants, Al(III) and Fe(III), as it has the advantages of having a constant optimum flotation pH (6.5) regardless of wastewater characteristics, as well as having a much lower detrimental effect on the flotation outcome when present in excess of the minimum requirement for flocculation of wastewater solids. This allows the setting of a coagulant dose (5 mM) that will treat both high and low solids content wastewater samples. The use of cationic surfactant (CTAB) was found to require lower coagulant dosages compared to those required for anionic (SDS) or non-ionic (TericG12A8) surfactants in order to achieve good flotation outcomes. A CTAB concentration of 300 ppm was required to achieve a stable foam that can sustain for a prolonged period to allow solid (in foam)/liquid separation. The optimum batch mode conditions for HLC flotation were found to be pH 6.5, 5 mM Fe(II) and 300 ppm CTAB. This was found to correspond to a small and negative electrophoretic mobility at the wastewater solid surface and large floc size. Batch mode flotation of individual ink components under the optimum conditions for industrial wastewater treatment revealed that the presence of large quantities of either blue or yellow inks in the wastewater can lead to poor removal. Their combined presence, however, did not have detrimental effects. Continuous mode flotation at 5 mM Fe(II), 300 ppm CTAB and pH 6.5 was found to remove above 96% of contaminants at cell residence times of 6 minutes and 88% of contaminants at cell residence times of 1.5 minute. Greater than 87% of the initial wastewater volumes were recovered as treated effluent (i.e. < 13% disposed as waste foam sludge), yielding a waste foam sludge containing between 12 and 17% solids. The best flotation outcomes were achieved when all the wastewater volume entering the flotation cell leaves the cell with the foam.
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Metz, Anneke Maria. "Function of the wheat eukaryotic initiation factors eIF(ISO)4G and eIF4B in translation /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.
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Lucho, Romero Cesar Stuardo. "Analysis of environmental factors in the adoption of iso/iec 29110. Multiple case study." Master's thesis, Pontificia Universidad Católica del Perú, 2017. http://tesis.pucp.edu.pe/repositorio/handle/123456789/9570.
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The software industry comprising small companies represents an interesting
opportunity for economic development. But these still have problems
in productivity and the quality of their delivered products. In this context, the
ISO/IEC 29110 standard has been developed, which represents an opportunity
for small companies whose adoption depends on several factors, in particular,
those related to the environment. In this paper, we study the influence of environmental
factors on the adoption of ISO/IEC 29110 standard. For this research,
a multiple case study was carried out, which includes four organizations as units
of analysis. In a controlled environment, each organization implemented the
processes belonging to the basic profile of the ISO/IEC 29110 standard. After
the implementation, an analysis has been made of the environmental factors that
influenced the adoption of the standard. Of the 16 environmental factors analyzed,
it was found that 6 factors influenced all the organizations and those related
to the support and trust of the partners had the greatest positive influence
on the standard adoption, while the defense factor of the partners had the most
negative influence. All other factors had minimal or no influence.<br>Trabajo de investigación
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Al-Asiri, Mohammad Mesaad. "FACTORS AFFECTING THE PRACTICES OF ISO 9001:2000 QUALITY MANAGEMENT SYSTEM IN SAUDI BUSINESS ORGANIZATIONS." Doctoral diss., University of Central Florida, 2004. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4360.
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Since it’s release in Dec 2000, there has been a slow movement towards the new version of ISO 9001:2000 by ISO 9000:1994 certified organizations. Of the 561,747 ISO 9000 certified businesses, 167,210 are certified under the new ISO 9001:2000, which is less than 30 % of the total ISO 9000 certified companies. Although many studies have been conducted to understand and assess the practices of ISO 9000:1994 standards, no research has been done to investigate the practices of ISO 9001:2000 in Saudi Arabia. This study is designed to investigate the implementation practices of the new ISO 9001:2000 standard in Saudi business organizations. The main objectives of this study are to identify the critical factors that lead to successful implementation of the new standard, to determine what barriers have been encountered during implementation, and to identify the most difficult parts of the standard to comply with.
It investigates the perceived benefits that Saudi firms have gained from implementing the system and examines the level of knowledge about ISO 9001:2000 and the perceptions of the new standard among the management teams and staff of ISO registered firms. It determines the level of integration between ISO 9001:2000 and other implemented systems. Furthermore, this study aims to investigate the factors that may explain the Saudi organizations’ decisions to implement ISO 9001:2000 in their businesses. To accomplish these research objectives, a questionnaire was developed based on an extensive review of related literature and tested for validity and reliability. The target sample for the study was made up of all ISO 9001:2000 registered sites in Saudi Arabia up to 31 Dec. 2002, which comprised 131 organizations. A total of 89 completed surveys were received, for a response rate of 72%.
Descriptive statistics, measurement of variation, and association, and factor analysis were used in the interpretation of collected data. The major findings are as follows: 86.5% of the total respondents had implemented ISO 9001:2000 as a transition process from previous ISO 9000 standards. 68.5% of the certified sites took less than one year to implement the standard. Most of them were previously certified in one of the ISO 9000:1994 standards. This high percentage indicates that ISO 9001:2000 can be easily implemented in a short time frame. Most of the companies in the study reported the use of external consultants (70.8%), but overall there was a low level of reliance on them, with 64.0% of registered organizations having documented less than 10% participation of external consultants in implementing the ISO 9001:2000 system.
The top five critical success factors in implementing the ISO 9001:2000 quality management system, in descending order, are as follows: commitment of management, effective internal auditing, commitment of middle management, employee motivation and involvement, resource allocation, and existence of appropriate communication routes. The major hindrances during the implementation of ISO 9001:2000, in descending order, were as follows: lack of employee involvement, difficulties in co-operation among middle managers over quality problems, lack of training programs related to quality, insufficient project time, and lack of customer co-operation. The most significant reasons for Saudi organizations to implement the system, in descending order, are as follows: top management initiative, quality improvement of internal operations and processes, customers requirements, part of the overall quality policy of the organization. The highest perceived benefits, in descending order, were as follows: development of quality culture, improved customer satisfaction, better communication with customers, increased management commitment, and use of data as a business management tool. Most respondents are highly satisfied with the standard, believe that it is cost effective and would strongly recommend the standard to other firms. Top managers were the most knowledgeable about the ISO 9001:2000 standard, followed by middle managers, then employees. Findings reveal that level of knowledge about ISO 9001:2000 among organization's people is positively correlated with most of the attainable benefits from implementing the standard. Based on the findings of this study, many conclusions and recommendations were drawn. In summary, for a successful implementation of ISO 9001:2000 standard, organizations must give great consideration to the people involvement factor, particularly top and middle management s involvement and commitment to quality, employees motivation and involvement, quality awareness, and ISO 9001:2000 training.<br>Ph.D.<br>Department of Industrial Engineering and Management Systems<br>Engineering and Computer Science<br>Industrial Engineering and Management Systems
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Holmström, Fredrik, and Jakob Hoffsten. "Förstudie till implementering av ISO 14001:2015 : Examensarbete 2020." Thesis, Tekniska Högskolan, Jönköping University, JTH, Logistik och verksamhetsledning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-49924.
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Syfte – Syftet med studien är att skapa ett underlag för små företag som ska implementera ISO 14001, genom att undersöka och identifiera kritiska faktorer samt lösningar för att överkomma dessa. Resultatet av studien kommer sedan användas för att skapa ett ramverk till små företag när de implementerar miljöledningssystemet ISO 14001:2015. Metod – För att nå studiens syfte, har en litteratursökning utförts för att etablera ett teoretiskt ramverk. Syftet med detta var att identifiera kritiska faktorer när en implementering av ISO 14001:2015 utförs. En fallstudie har även utförts på ett tillverkande företag för att kunna samla in empiriska data. Metoderna som har använts i studien är intervjuer, enkäter och observationer. Den empiriska data och det teoretiska ramverket jämfördes och analyserades för att svara på studiens syfte och frågeställningar. Resultat – I det teoretiska ramverket och fallstudien, identifierades fem kritiska faktorer; kunskap och kompetens, involvering av anställda, resurser, identifiering av miljömål och företagets miljöpåverkan och företagskultur. Engagemanget från ledningen på företaget identifierades även som en kritisk faktor, men var starkt kopplat till kunskap och kompetens. Faktorn valdes därför att inkluderas i kunskap och kompetens. För att överkomma dessa, identifierades lösningar till dem kritiska faktorerna. Resultatet av lösningarna var att alla kritiska faktorer har en stark korrelation med varandra och att lösningarna var liknande. Träning och utbildning av dem anställda var en nyckel-lösning för att lösa dem kritiska faktorerna. Implikationer – Studien kan användas som ett ramverk och bidra som underlag till små företag som vill implementera ISO 14001:2015. Studien har identifierat kritiska faktorer vid implementeringen och hur man överkommer dessa, oavsett vilken bransch som företagen arbetar i, vilket gör att studien kan användas av olika typer av företag. Begränsningar – Eftersom restriktionerna som samhället har satt på grund av COVID19 pandemin, har antalet observationer och intervjuer blivit begränsade. Detta har vidare påverkat trovärdigheten på studien negativt. Fler observationer och intervjuer hade gett ett mer trovärdigt resultat.<br>Purpose – The purpose of this study is to examine and identify critical factors as well as solutions to overcome these. The results will then be used to create a framework for small businessesto use when implementing the environmental management system ISO 14001:2015. Method – To reach the purpose of this study, a literature review has been conducted in order to establish a theoretical framework. The purpose of the theoretical frameworks was to identify critical factors when implementing ISO 14001:2015. A case study has also been conducted on a manufacturing company in order to collect empirical data. The methods used in the case study were interviews, surveys and observations. The empirical data and the theoretical framework were later compared and analysed to answer the study’s purpose and research questions. Findings – In the theoretical framework and the case study, five critical factors were identified: knowledge and competence, involvement of employees, resources, identifying environmental goals and the company’s environmental impact and corporate culture. The commitment of the senior management was also identified as a critical factor, but was strongly related to knowledge and competence, and therefore it was included in that critical factor. To overcome the critical factors, solutions to each critical factor was identified. With all the solutions identified, it was concluded that all the critical factors are strongly related. Furthermore, the solutions to overcome the critical factors were similar, where training and education of employees was a key solution to overcome the critical factors. Implications – The study can be used as a framework and provide help for small business that want to implement ISO 14001:2015. The study has identified critical factors in the implementation and how to overcome these, regardless of the area that companies work within and can therefore be used by different types of companies. Limitations – Because of the restrictions in the society following the COVID-19 pandemic, the amount of observations and interviews that should have been conducted was limited and therefore the credibility of the study was affected in a negative way. More observations and interviews would have given a more credibly result.
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Harris, Jennifer. "Regulation of nuclear factor kappa B subunit c-Rel through phosphorylation by two IKK-related kinases, IKK epsilon and TBK-1." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82250.
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The nuclear factor kappaB (NF-kappaB) transcription factors are key regulators of immunomodulatory genes regulation. NF-kappaB activity is regulated through the phosphorylation of inhibitory proteins (IkappaBs) by the IkappaB kinase (IKK) complex (IKK alpha/beta/gamma), leading to IkappaB degradation and NF-kappaB translocation to the nucleus where they promote transcription of immunoregulatory genes. Moreover, cRel and p65 activities are also regulated by direct phosphorylation of their transactivation domain. Recently, two IKK non-canonical homologues, IKKepsilon and TBK-1 (TANK binding kinase-1) have been identified with functions distinct from the classical IKKalpha/IKKbeta. TBK-1/IKKepsilon trigger antiviral immunity through direct phosphorylation of the IRF3/IRF7 transcription factors, which are key regulators of the interferon response. Since IKKepsilon modulates the activity of IRF3/IRF7, it is of interest to assess whether IKKepsilon/TBK-1 also regulates the transactivation activity of NF-kappaB. Our hypothesis was that IKKepsilon/TBK-1 modulates the activity of cRel by direct phosphorylation of its transactivation domain (TD). In this study, we demonstrate that IKKepsilon and TBK-1 directly phosphorylate cRel in vitro and in vivo. Two of the three consensus sequences recognized by IKKepsilon/TBK-1 in the cRel TD are directly phosphorylated by IKKepsilon. cRel was translocated to the nucleus in cells expressing wild type versus kinase dead variant. The expression of IKKepsilon increases c-Rel transactivation in reporter gene assays. Serine to alanine mutation was further used to characterize the function of this phosphorylation at the level of nuclear translocation and transactivation potential using immunofluorescence and reporter gene assay. Furthermore, co-expression studies revealed that IKKepsilon and not the kinase dead variant is responsible for cRel degradation in a dose-dependent manner and this effect is partially revert
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Marjanen, Yka. "Validation and improvement of the ISO 2631-1 (1997) standard method for evaluating discomfort from whole-body vibration in a multi-axis environment." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/6250.
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Vibration exposure can occur at work, commuting between home and work, and in leisure activities. Any form of transportation will expose humans to some degree of vibration. Exposure to vibration can cause health problems, but more likely comfort problems. Health problems are normally related to back pain. Comfort on the other hand is related to both physiological and psychological factors, which can have a wide range of effects from a general annoyance to a reduced work capability. The standard ISO 2631-1 (1997) provides a guidance, which can be used to measure, evaluate and assess effects of whole-body vibration to discomfort. The standard allows several interpretations, which can lead to different results, as the standard does not provide an explicit guidance for selecting which axes and locations to measure and which averaging method to use for evaluating the axes. The suggested averaging method is the root mean square (r.m.s.) method, but additionally vibration dose value (VDV) can be used. This can lead to different results, as VDV emphasises shocks more than the r.m.s. method. The standard guides to measure and evaluate at least the seat translational axes, but the additional nine axes from the seat, backrest and floor are not mandatory. However, this can result in a different comfort value, as the values from the measured axes are combined. So taking into account all possible interpretations the assessment can vary significantly for the same environment. The selection of the averaging method is not a technical issue, as both methods are supported by all commercial equipment. However, it is rare that more than three axes are possible to be measured with typical whole-body vibration measurement equipment, thus the majority of studies have published results based on only the seat translational axes. Especially the rotational axes have been missing in most studies. The full method (i.e. using all possible axes to calculate the comfort value) of ISO 2631-1 (1997) has been rarely used and there is very little information on how accurate the method is for assessing discomfort in a multi-axis environment. There are only a few studies that have used the full method, but there are no known studies which have actually validated the full ISO 2631-1 method. The objective of the thesis was to validate and, if necessary, to improve the full method of the ISO 2631-1 standard for evaluating discomfort from whole-body vibration in a multi-axis environment. It was assumed that the ISO 2631-1 method can be used to predict discomfort in practice, but there are a relatively low number of studies to confirm this. Frequency weightings have been the focus of many published studies and it was assumed that these are broadly correct. Other aspects of the ISO 2631-1 method are the focus of this thesis. The goal was to keep a backward compatibility to previous studies and the current commercial equipment, thus several limitations were defined for the improvement of the standard. Several laboratory experiments, field measurements, and field and laboratory trials were conducted to validate the standard method. At first it was concluded that practical equipment for measuring 12-axis data was needed as there was no commercial system available. The equipment and software was validated in two experiments, which showed that simple and affordable components could be used to develop equipment for the full method. Even though the standard does not include information about a six-axis sensor for measuring both translational and rotational axes, there was a method to validate the sensor. The first field study included measuring several machines using all twelve axes. The analysis showed that the seat and backrest translational axes will contribute about 90 % of the overall vibration total value of the standard method, thus very little justification was found for including the seat rotational and floor translational axes. Similar results were found based on the data from the previous 12-axis studies. It was also found that the neglected axes could be compensated with a factor for estimating the overall vibration total value including all twelve axes. As the overall vibration total value is directly related to the number of used axes, the compensating factors can be used to compare results which used different axes. The laboratory trial confirmed the results from the field study, and it was concluded that sufficient accuracy to predict discomfort can be achieved using just the seat translational axes, even though the correlation improved when more axes were included. It was found that the evaluation of discomfort was improved by the use of the frequency weighting curves and the r.m.s. averaging method. However, as the multiplying factors degraded correlation, it was concluded that a new set of factors should be calculated. The new factors showed that a higher emphasis on the seat horizontal axes should be given (x=2.7, y=1.8 and z=1.0). The new factors improved the correlation systematically for all subjects. The field trial showed a similar trend, where optimised multiplying factors improved the correlation, but it was also noted that different multiplying factors are required for different environments, thus a procedure to optimise the standard method to different environments was developed. The trial showed systematic behaviour and the optimised multiplying factors were best for all subjects and groups. Keywords: Discomfort, whole-body vibration, standard, ISO 2631-1, multi-axis, multiplying factors
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Murphy, Eileen. "Key success factors for achieving green supply chain performance : a study of UK ISO 14001 certified manufacturers." Thesis, University of Hull, 2012. http://hydra.hull.ac.uk/resources/hull:8412.
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Recently, there has been increasing emphasis on the use of voluntary environmental protection instruments such as environmental management systems (EMS). One such system is ISO 14001 which is designed to assist organisations to create a structured mechanism for continuous improvement in environmental performance. However, more knowledge is required to identify the impact these systems have on the actual environmental supply chain practices performance (GSCPP) of manufacturing organisations. Furthermore many investigations of the supply chain are based on ―hard‖ factors such as the application of systems and tools to achieve performance goals. What are less appreciated are the effects of human dimensions of managing relationships with employees and suppliers. Accordingly this research will investigate the relations and dynamics of the Key Success Factors (KSF), (training, communication, management support, employee responsibility, rewards and recognition, employee involvement, and supplier management) which are believed to assist in the improvement of GSCPP of manufacturing companies. This research sets its objectives on advancing the knowledge and understanding of the roles of key success factors in supply chain operations, how these KSF function as separate factors or work together and how they are being put into practice in manufacturing organisations. A mixed method explanatory approach adopting a questionnaire survey and semi-structured interviews are used to describe these phenomena and explore the reasons for and reveals inhibitors of the implementation of KSF. Key findings from this study are the development of a new mega-construct to measure internal soft management practices in organisations. Organisations successfully achieving green supply chain performance are applying a combination of key success factors such as employee responsibility and collaboration with suppliers. In-depth case studies also illustrate how these KSF manifest themselves and work together in real life. Evidence from the analysis demonstrates that despite the ISO 14001 certification some organisations are behaving in a more reactive fashion providing only the bare minimum in terms of training, where there is little emphasis on involvement of their employees, and where the management is largely unsupportive of a more comprehensive and integrated EMS. This research has three areas of contribution; to researchers who wish to further examine the combination of both hard and soft interpretations for environmental supply chain performance; to management practitioners who will benefit from the resulting tool will be able to assess the steps required to improve performance; and to those responsible for reviewing ISO 14001 who may include KSF and thus pass on the benefits to participating organisations.
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Pickens, David Bruce III. "EXPERIMENTAL ASSESSMENT OF THE DYNAMIC FACTORS OF FZG GEAR TESTS AS WELL AS AN EVALUATION OF A MICROPITTING LOAD CAPACITY FORMULA." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1345160456.
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Gomes, Eendrik Lima. "Índice de sustentabilidade empresarial (ISE) da BM&FBOVESPA: Motivação para Buscar a Adesão." Universidade do Vale do Rio dos Sinos, 2017. http://www.repositorio.jesuita.org.br/handle/UNISINOS/6347.
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Previous issue date: 2017-04-19<br>CFC/CRCs - Conselho Federal de Contabilidade<br>O presente trabalho objetivou investigar quais fatores são relevantes na decisão da empresa de buscar adesão ao ISE da BM&FBOVESPA. Foram verificados os seguintes fatores para adesão ao ISE: ser reconhecida pelo mercado como empresa que atua com práticas sustentáveis, promovendo a reputação da empresa, a transparência na evidenciação das ações da empresa, o engajamento entre os envolvidos, a vantagem competitiva, e buscando novos conhecimentos, redução de custo de capital a longo prazo, antecipação das regulamentações que podem ser estabelecidas no futuro, aumento no valor da empresa, fortalecimento dos canais de diálogo e comunicação com mídia e indicador para mensurar as ações e práticas sustentáveis. Foram identificados como fatores para não adesão ao ISE: critérios do ISE, estratégia da empresa, falta de estrutura, custos, desconhecimento da carteira do ISE, falta de benefícios e em avaliação para adesão. Metodologicamente, o estudo caracteriza-se como descritivo, realizado por meio de entrevistas e com uma abordagem qualitativa, utilizando o método de análise de conteúdo de Bardin (2011), para tratamento de dados. A coleta de dados teve como base o conjunto de 243 empresas que foram consideradas elegíveis para compor o ISE pelo menos um ano, entre 2009 e 2016. Após, foram selecionadas 74 empresas para composição da amostra. Este conjunto de empresas da amostra, por sua vez, foi subdividido em dois grupos: 1) 22 empresas que tentaram ingressar na carteira do índice, e 2) 52 empresas que não tentaram ingressar no ISE. Concluiu-se que as empresas buscam o ISE, principalmente, para serem reconhecidas pelo mercado e a fim de terem um indicador para mensurar as ações e as práticas sustentáveis. Sendo assim, trata-se de uma ferramenta brasileira importante e reconhecida, que certifica as empresas que possuem um maior comprometimento com a responsabilidade socioambiental.<br>The present work aimed to investigate which factors are relevant in the decision of the company to seek adhesion to the BM & FBOVESPA ISE. The following factors were verified for adherence to the ISE: to be recognized by the market as a company that acts with sustainable practices promoting the company's reputation, transparency in the disclosure of company actions, engagement among stakeholders, competitive advantage, new knowledge seeking, cost reduction Long-term capital, anticipation of regulations that can be established in the future, increase in the value of the company, strengthening channels of dialogue and communication with the media and an indicator to measure sustainable actions and practices. And the factors for non-adherence to ISE were: ISE criteria, company strategy, lack of structure, costs, lack of knowledge of ISE's portfolio, no benefits and evaluation for membership. The study is characterized as descriptive, conducted through an interview and with a qualitative approach, using the content analysis method of Bardin (2011) for data treatment. The data collection was based on the set of 243 companies that were considered eligible to compose the ISE for at least one year between 2009 and 2016. We selected 74 companies for sample composition. This group of companies in the sample, in turn, was subdivided into two groups: 1) 22 companies that tried to enter the index portfolio, and another; 2) 52 companies that did not try to join the ISE. It was concluded that companies seek ISE mainly to be recognized by the market and as an indicator to measure sustainable actions and practices, being an important and recognized Brazilian tool that certifies companies that have a greater commitment to social and environmental responsibility.
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Rehnvall, Malin, and Johanna Strand. "Professionellas uppfattning om användbarheten av en checklista (Check: IRK) för initial riskbedömning av riskfaktorer för kriminalitet." Thesis, Örebro universitet, Institutionen för juridik, psykologi och socialt arbete, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-42718.
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Check: IRK (Initial Riskbedömning för Kriminalitet) är en nyutvecklad evidensbaserad checklista tänkt att användas av professionella i initiala bedömningar för att identifiera riskfaktorer för kriminalitet hos ungdomar och vuxna med risk för långvarigt kriminellt beteende. Syftet med vår studie var att i en första pilottestning ta reda på hur professionella inom polis och socialtjänst uppfattar användbarheten av Check: IRK. Via en webbenkätundersökning besvarade 21 respondenter, varav 6 män och 15 kvinnor mellan 26-47 år (M=36 år, SD=6,70) på frågor gällande innehåll, tillämpning och utbildning i Check: IRK. Studiens data analyserades med Z-test och resultaten indikerar att utifrån innehåll, tillämpning och utbildning i checklistan så uppfattar professionella inom polis och socialtjänst Check: IRK som användbar i sitt arbete.<br>Check: IRK is a newly developed evidence-based checklist designed to be used by professionals in the initial assessment to identify risk factors for criminality in adolescents and adults at risk of long-term criminal behavior. The current pilot study investigated how professionals within the police and social services perceived the usefulness of Check: IRK. Through a web survey 21 respondents including 6 men and 15 women between the age of 26-47 years (M=36 years, SD=6,70) answered questions regarding the content, implementation and training of the Check: IRK. Data were analyzed using Z-test and the results indicated that professionals within the police and social services find the Check: IRK to be useful in their daily work.
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Montagni, Elisa 1984. "Transcription factor GATA6 and ISC gene SMOC2 in the regulation of BMP pathway in intestinal adenoma." Doctoral thesis, Universitat Pompeu Fabra, 2015. http://hdl.handle.net/10803/523489.
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The first chapter identifies the transcription factor GATA6 as negative regulator of a transcriptional circuit dedicated to prevent the expansion of Adenoma Stem Cells (AdSCs) during the onset of colorectal cancer (CRC). In particular, we show that GATA6 directly activates the expression of the WNT pathway component LGR5 and represses BMP levels in adenoma by competing with the β-catenin/TCF4 complex for the binding to BMP4 enhancer regions. As a result of this mechanism, two compartments are established within an adenoma: a BMP positive differentiated cell zone and a BMP negative undifferentiated cell zone, where AdSCs reside. Genetic deletion of Gata6 increases BMP levels in the AdSC compartment, inhibiting self-renewal and intestinal tumorigenesis. These findings represent a key contribution to understand the mechanisms that regulate tumor hierarchy and reveal for the first time the existence of a niche that protects AdSCs from BMP signals.
The second chapter focuses on the functional characterization of Smoc2, a novel Intestinal Stem Cell (ISC) gene. We generated genetic mouse models in order to overexpress or ablate Smoc2 in the intestine. We found that SMOC2 acts as a BMP inhibitor in the intestine and that it is not only restricted to epithelial Stem Cells (SCs) but it is also expressed by the stroma. Although it is dispensable for normal ISC maintenance and intestinal homeostasis, high levels of SMOC2 are required for tumorigenesis. Indeed, Smoc2 overexpression leads to spontaneous development of hamartomas and enhances adenoma formation in mice with an Apc mutant background; inversely, Smoc2 deficiency decreases tumorigenesis and prolongs survival of Apc mutant mice. In particular, we observed that SMOC2-mediated BMP inhibition positively affects Insulin-like Growth Factor (Igf1) expression in adenoma endothelial cells (ECs). Our data suggest that SMOC2 could enhance tumor-associated inflammation through BMP-mediated Igf1 regulation in the stroma.<br>El primer capítulo describe la identificación del factor de transcripción GATA6 como regulador negativo de un circuito transcripcional fisiológico dedicado a reprimir la expansión de las células madre de los adenomas (Adenoma Stem Cells o AdSCs) en el inicio de la tumorogénesis colorrectal. De manera específica, mostramos como el factor GATA6 activa directamente la expresión del componente de la ruta de WNT, LGR5, y también directamente reprime niveles de hormona BMP (Bone Morphogenetic Protein) a través de la competición directa con el complejo beta-catenina-TCF4 por la unión a regiones enhancer del gen BMP4. Como resultado de este circuito transcripcional que hemos descubierto, en los adenomas se generan dos compartimentos, una zona positiva para la señalización mediada por BMP que contiene las células diferenciadas de los adenomas, y un área negativa para BMP, donde residen y se expanden las AdSCs. La ablación genética de Gata6 incrementa los niveles de BMPs en el compartimento de las AdSCs, inhibiendo la autorenovación de las mismas y por ende la tumorogénesis. Este descubrimiento representa una aportación clave para entender los mecanismos que regulan la jerarquía tumoral y revelan por primera vez la existencia de un nicho que protege las AdSCs de las señales de BMP.
El segundo capítulo describe la caracterización funcional de Smoc2, uno de los genes identificados en el laboratorio dentro del programa genético específico de las células madre del intestino (Intestinal Stem Cells o ISCs). Durante el transcurso de la tesis
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Eiberger, Edgar Ludwig Eugen. "Insulin-like Growth Factor I (IGF-I), IGF Binding Protein-3 (IGFBP-3) und Alkalische Phosphatase (AP) bei organischem Wachstumshormonmangel (GHD), intrauteriner Wachstumsretardierung und idiopathischem Kleinwuchs (ISS)." [S.l. : s.n.], 2003. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB10732978.
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Almakadmeh, Khaled. "Development of a scaling factors framework to improve the approximation of software functional size with COSMIC - ISO 19761." Mémoire, École de technologie supérieure, 2013. http://espace.etsmtl.ca/1190/1/ALMAKADMEH_Khaled.pdf.
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De nombreuses organisations de développement de logiciels s’efforcent de fournir des produits de haute qualité tout en gardant un équilibre entre la satisfaction du client, le calendrier et le budget. L'estimation de l'effort de développement des projets logiciel est l'un des défis majeurs de ces organisations de développement et ce défi est généralement rencontré dès les premières phases du cycle de vie du développement.
Pour relever ce défi, les organisations de développement de logiciels utilisent des techniques d'estimation précoce pour obtenir des estimations de l'effort au début (c.-à-d. estimations a priori) afin d'aider les gestionnaires de projet et les responsables techniques dans la planification et la gestion des projets.
L'une des approches pour l’estimation de l'effort a priori est basée sur l'approximation des fonctions attendues du logiciel. Ceci nécessite l'utilisation d'une méthode de mesure pour quantifier ces fonctions: la littérature réfère à la mesure de la taille fonctionnelle des produits logiciels - incluant les applications d'entreprise. Différentes normes internationales ont été adoptées pour mesurer la taille fonctionnelle des logiciels, telle que ISO 19761: COSMIC.
Cependant, durant les premières phases du cycle de vie du développement logiciel, et plus spécifiquement dans le processus d’estimation de la taille fonctionnelle du logiciel, l'absence de spécifications complètes et détaillées des exigences logicielles est commune, ce qui entraîne de nombreux défis. Par exemple: le niveau de granularité (c.-à-d. le niveau de détail) de la spécification des exigences fonctionnelles du logiciel est identifié subjectivement en utilisant l'intuition, l'expérience et/ou les opinions des experts du domaine; les facteurs d'échelle ne sont pas attribués; il n’y a pas une notation standardisée pour définir un ensemble standard de facteurs d'échelle que les ingénieurs des exigences peuvent affecter aux spécifications des exigences fonctionnelles des nouveaux projets de développement de logiciels afin d'identifier leur niveau de granularité.
Ces défis affectent l’estimation de la taille fonctionnelle de nouveaux projets de développement de logiciels puisque le résultat de l’estimation de la taille fonctionnelle est l'une des entrées principales du processus d'estimation d'effort. Ces défis empêchent les gestionnaires des projets logiciels de construire des modèles réalistes d'estimation de l'effort pour les nouveaux projets de développement de logiciels.
La motivation de ce projet de recherche est d'aider les organisations du développement logiciels et, en particulier, les gestionnaires des projets et les responsables techniques pour construire des modèles d'estimation de l’effort plus précis et ce en améliorant l'une des entrées du processus d'estimation de l'effort, afin d'améliorer la planification, la gestion et le développement des logiciels à des phases précoces du cycle de vie du développement des logiciels.
Le but de ce projet de recherche est d'améliorer l'une des entrées du processus d'estimation de l'effort et en particulier la qualité de l’approximation de la taille fonctionnelle des nouveaux projets du développement des logiciels.
L'objectif principal de la recherche est de concevoir un cadre de référence à être utilisé par les ingénieurs des exigences pour attribuer des facteurs d'échelle pour les premières versions de la spécification des exigences fonctionnelles du logiciel afin d’identifier leur niveau de granularité, ce qui se déroule généralement après l'étape de l'étude de faisabilité pour les nouveaux projets du développement logiciels.
Pour atteindre cet objectif de recherche, les principales phases de la méthodologie de recherche sont:
• la phase de recherche exploratoire: pour d'étudier l'impact du problème de recherche sur l'approximation de la taille fonctionnelle;
• la phase de conception du cadre de référence: pour concevoir la cadre de référence qui attribue les facteurs d'échelle à des spécifications fonctionnelles des exigences fonctionnelles pour identifier leurs niveaux de granularité; et
• la phase de vérification du cadre de référence: c’est la phase qui vérifie la convivialité du cadre de référence grâce aux différents groupes de participants ayant des profils d'expérience différents, et qui vérifie l'applicabilité de cadre de référence avec une variété d'études de cas représentant des systèmes logiciels différents.
Le principal résultat de ce projet de recherche est un cadre de référence qui se compose:
• d'un méta-modèle qui identifie les concepts et leurs relations qui doivent être recueillies par les ingénieurs des exigences pour atteindre la pleine spécification fonctionnelle des spécifications des exigences logicielles; et
• les critères qui permettent d'identifier le niveau de granularité de la spécification des exigences logicielles, et de leur attribuer des facteurs d'échelle pour classer leurs niveaux de granularité.
Le cadre de référence a été vérifié pour utilisation avec la même étude de cas par trois groupes de participants de l'industrie du génie logiciel, tandis que son applicabilité a été vérifiée avec quatre études de cas.
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Sharif, Ahmed Bashir. "Critical success factors affecting the implementation of the ISO 9001:2000 quality management system in Libyan manufacturing companies." Thesis, University of Salford, 2009. http://usir.salford.ac.uk/26908/.
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Since ISO 9000 was introduced in 1987 the number of organisations in developed and developing countries with ISO 9000 certification is increasing dramatically. Up to the end of 2006, the number of ISO 9001:2000 certified organisations reached 40,909 in the UK and 44,883 in the USA. Within Arab countries the number reached 1,928 in Egypt, 710 in Saudi Arabia and 1,040 in the United Arab Emirates. In Libya, however, this number up to the end of 2006 was only 46 and, according to the results of the conducted preliminary interviews of this study, the number of certified Libyan Manufacturing Companies (LMCs) up to the end of September 2007 was only 7 companies which is, relatively, a very low number. Accordingly, this thesis aims to "investigate the critical success factors (CSFs) affecting the implementation of ISO 9001:2000 in Libyan manufacturing companies'". A comprehensive review of literature was carried out to identify the critical success factors affecting the implementation of ISO 9001:2000 that were experienced by different organisations around the world, including its key aspects. The summarized factors were subsequently used in the empirical investigation of the relevant factors in LMCs. The employed research methodology involved the adoption of a quantitative approach, a survey strategy, utilising a self-administrated questionnaire method. All 7 certified companies were included in the survey. The Statistical Package for the Social Sciences (SPSS) was used to analysis the data using appropriate statistical techniques. The survey findings revealed that LMCs experienced many factors, these mostly being the same as those experienced by other companies in different countries. There was a relative degree of difference in the importance. These factors as identified in this study are presented in five groups. These groups in descending order are: management and people involvement, culture, training, communication, and support mechanism. The most critical success factor for ISO 9001:2000 implementation in LMCs is represented in the management and people involvement group which is the "top management commitment" factor. The study, therefore, contributes to the existing body of knowledge in the quality management discipline and fills the gap in knowledge in Libyan studies. Recommendations for further research also have been derived from this research.
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Pino, Malpica Isabel Corina. "Análisis de los factores de éxito y limitantes para la implementación de la norma técnica peruana Iso NTP/IEC 27001;2014 2A. Edición en la Municipalidad provincial de Huancayo–I trimestre 2018." Bachelor's thesis, Universidad Continental, 2019. http://repositorio.continental.edu.pe/handle/continental/5527.
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La Presidencia de Consejo de Ministros (PCM) emitió un conjunto de normas entre ellas algunas relacionadas a la seguridad de la información, con la cual se dispuso la obligatoriedad de uso de la NTP ISO/IEC 27001:2008 (aprobada con RM Nº 129-2012- PCM del 4 de junio de 2012), posteriormente la Norma Técnica Peruana NTP-ISO /IEC 27001:2014 2da Edición (aprobada con RM N° 004-2016-PCM del 8 de enero de 2016). Sin embargo, han pasado 6 años desde entonces, y pocas entidades han logrado la implementación total de la norma, es por ello que este trabajo de investigación tiene como objetivo identificar estos factores de éxito o limitantes para la implementación de la norma.
La investigación se desarrolló en la Municipalidad Provincial de Huancayo, para lo cual elabore un check list en base a lo que solicita la norma y verifique la existencia en la Municipalidad durante I trimestre del año 2018, cualquiera fuese el resultado se solicitó información de los factores que permitieron el nivel alcanzado. Al finalizar la investigación se identificó que la entidad implemento 32% de lo solicitado por la norma, que algunos de los factores de éxito fue el conocimiento, experiencia e interés por parte del funcionario público responsable, y entre los limitantes la falta de procesos, cultura organizacional, presupuesto y capacitaciones.
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Mendes, Joyce Martins. "Avaliação de serviços convergentes em ambientes heterogêneos." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/3/3141/tde-10092007-113414/.
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Este trabalho propõe um modelo de avaliação da aceitabilidade de produtos, incluindo serviços, softwares, equipamentos e modelos de negócio além de um método de aplicação na avaliação de serviços convergentes em ambientes de redes heterogêneas aplicado diretamente aos usuários potenciais.Este modelo permite ainda atingir uma amostragem significativa de usuários com expressiva diversidade cultural de maneira concisa e eficaz, com baixo custo através da utilização da Web.<br>This work proposes a products acceptability evaluation model, including services, software, equipments and business models, besides an application method for convergent services evaluation in heterogeneous networks environments, applied directly to the potential users. This model allows, yet, reach an users\' significant sampling with an expressive cultural diversity in a concise and effective way, with low cost through the Web utilization.
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Liveris, Panagiotis D. "New public management reforms : an empirical study of human resources critical factors, in the context of the Greek public sector." Thesis, University of Derby, 2015. http://hdl.handle.net/10545/576013.
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This work is an endeavour on the subject of the Critical Success Factors imposed by Human Resources, in the process of reforms, under the context of New Public Management, particularly, as this applies in the Greek Public Sector and more specifically in the cases of ISO implementation. The fundamental issues it attempts to elucidate are the Human Resources policies that must be applied, so that employees become an integral element for the successful implementation of any introduced reforms. Many scholars have pointed out the gap in literature regarding the effect of New Public Management (NPM) reforms on the human factor. Moreover, in the current Greek reality, in the context of the economic recession and the debt crisis, where public administration reforms are mandatory, the thorough examination of the vital issues, pertaining to Human Resources, consists a major priority. The qualitative research method applied with the employees of the reformed organisations has further aspired to ponder and determine what really matters during the transformational process from the employees’ point of view. The conclusions we have reached underpin the importance of Human Resources motivational factors in the reform process, taking into consideration that the employee is the catalyst for any change effort. Some of those factors were found to be also part of the ISO concept per se, thus, their implementation would boost the employees’ morale, while others must be carefully analysed, planned and implemented by all the stakeholders to further facilitate the change process. We have to bear in mind that, especially under the current dire economic environment, quality reforms could be a challenge, as they combine fiscal discipline and at the same time aspire to increase the employees’ and citizens’ satisfaction. This study goes further to suggest that, the implementation of ISO reforms could help all the participants, provided that the decision makers take into serious consideration the Critical Success Factors outlined herewith, that have been extracted from a survey conducted pertinent to our research. This study focused on the reforms/ISO process as implemented by the Intermediate Managing Authority of the Ionian Islands. Further research on the implications from the implementation of NMP doctrines on Human Resources should be conducted in other Greek governmental organisations, in order to reaffirm the results and possibly enhance the suggested model. Conclusively, our ultimate target is to assist decision makers and encourage them to utilise the arguments depicted, towards the successful implementation of NPM doctrines.
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Sundaram, Preethi. "New Results For Characterization Of Indoor Channels In Two Ism Bands (900-928 Mhz And 2.4-2.5 Ghz)." Ohio University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1140462634.
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Santos, Roberta de Oliveira. "Caracterização da população adulta e idosa do município de São Paulo segundo padrões alimentares de refeições - Estudo de base populacional ISA Capital 2008." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-03112014-125106/.
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Introdução: A Organização Mundial da Saúde sugere que as recomendações alimentares para populações devem basear-se em alimentos ao invés de nutrientes. No entanto, devem levar em consideração, que os indivíduos não consomem nutrientes ou alimentos isoladamente e sim refeições compostas por uma variedade de alimentos. Objetivo: Identificar os padrões alimentares do café da manhã, almoço e jantar da população adulta e idosa do município de São Paulo e caracterizá-los de acordo com variáveis socioeconômicas, demográficas e antropométricas. Métodos: Foram utilizados dados secundários do estudo transversal de base populacional ISA-Capital 2008 de adultos e idosos (n=1102). O consumo alimentar foi estimado pelo Multiple Source Method considerando dois recordatórios de 24 horas. A partir dos grupos de alimentos de cada refeição aplicou-se análise fatorial por componentes principais (rotação varimax) para derivar os padrões alimentares. Calcularam-se os escores fatoriais, que foram então utilizados para agrupar os indivíduos através da análise de agrupamento. Adicionou-se um grupo com os indivíduos que não realizaram a refeição para cada uma das análises. Os grupos foram caracterizados segundo sexo, faixa etária, renda familiar per capita e estado nutricional. Admitiu-se nível de significância de 0,05 e para caracterização dos grupos considerou-se uma diferença de escore padronizado em pelo menos |0,5| com relação à amostra geral. Resultados: Identificou-se prevalência de 5,6 por cento de omissão do café da manhã, 3,6 por cento do almoço e 12,8 por cento do jantar. Quanto aos que realizaram as refeições, identificaram-se três padrões do Café da Manhã: Saudável, Tradicional e Lanche; quatro padrões do Almoço: Tradicional, Salada, Suco Adoçado e Ocidental; e quatro padrões do Jantar: Café com Leite e Pão, Transição, Tradicional e Sopa e Frutas. Os grupos de indivíduos associados a idosos apresentaram aderência ao café da manhã Saudável, almoço Salada e jantar Sopas e Frutas. Aqueles associados a homens e adultos em geral omitiram o café da manhã e aderiram ao almoço Ocidental e jantar Transição. Os grupos associados a apenas homens aderiram a café da manhã e almoço Tradicional. Aqueles associados a somente adultos apresentaram aderência ao almoço Suco Adoçado. E associados a mulheres aderiram a um jantar Café com Leite e Pão. Grupos associados à baixa escolaridade aderiram a um jantar Sopa e Frutas, e os de escolaridade elevada aderiram a café da manhã Lanche e Omissão do mesmo; e padrão de almoço ocidental. Grupos associados com indivíduos de baixa renda aderiram ao almoço tradicional. Conclusão: Os resultados encontrados no presente estudo indicam que padrões alimentares identificados de acordo com a refeição discriminam bem o consumo alimentar, salientando peculiaridades que não são encontradas em análises globais. E a associação entre a aderência a esses padrões e fatores demográficos e socioeconômicos sugere a existência de públicos-alvo para o planejamento e execução de políticas públicas em alimentação e nutrição.<br>Introduction: The World Health Organization suggests that dietary recommendations for populations should be based on foods rather than nutrients. However, individuals do not consume foods or nutrients in isolation but meals with variety of foods. Objective: To identify dietary patterns from breakfast, lunch and dinner of the adult and elderly population in São Paulo and characterize them according to socioeconomic, demographic and anthropometric variables. Methods: Data from cross-sectional population-based ISA Capital 2008 of adults and elderly (n = 1102) was used. Dietary intake was estimated by Multiple Source Method considering two 24-hour recalls. Principal component factor analysis (varimax rotation) was used to derive dietary patterns for each meal. Factor scores were calculated and then used in the cluster analysis. Individuals that skipped the meal were added as an extra cluster. The groups were characterized by gender, age, family income and nutritional status. Significance level of 0.05 was assumed for the groups characterization it was considered a difference of standardized score of at least | 0.5 | with respect to the overall sample. Results: We found omission prevalence of 5.6 per cent for breakfast, 3.6 per cent for lunch and 12.8 per cent for dinner. Three patterns of breakfast were identified: Healthy, Traditional and Snack; four patterns to lunch: Traditional, Salad, Sweetened Juice and Western; and four patterns to dinner: Coffee with Milk and Bread, Transitional, Traditional and Soup and Fruits. The groups of individuals associated with the elderly showed adherence to Healthy breakfast, Salad lunch and Soups and Fruit dinner. The groups that were associated with adult and men skipped breakfast and adhered to the Western lunch and Transition dinner. The groups associated with only men showed adherence to Traditional breakfast and lunch. The groups associated with only adults showed adherence to Sweetened Juice lunch. The groups associated with women showed adherence with Coffee with Milk and Bread dinner. The groups associated with low education adhered to Soup and Fruits dinner, and the groups associated with high school skipped breakfast and they adhered to Snack breakfast and Western breakfast. Groups associated with low-income individuals adhered to Traditional lunch. Conclusion: The results of this study indicate that dietary patterns identified by meal discriminated food consumption very well, highlighting peculiarities that a global analysis cannot show. And the adherence to meal patterns associated with socioeconomic and demographic factors suggest there is evidence of risk groups and possible public policies related to health diet.
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Subramanian, Gayatri. "TDRD7, a Novel Viral Restriction Factor, Inhibits Cellular AMP-dependent Kinase to Inhibit Virus Replication." University of Toledo Health Science Campus / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=mco1596574176173965.
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Lecampion, Cecile. "Rôle respectifs des facteurs d'initiation de la traduction eIF4E ET eIF (ISO) 4E chez Arabidopsis thaliana." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4096/document.
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L’initiation de la traduction est un processus complexe qui fait intervenir une douzaine de facteurs d’initiation. L’élément clef de ce mécanisme est le facteur eIF4E qui grâce à sa liaison avec la coiffe, recrute l’ensemble du complexe d’initiation au niveau de l’ARNm et permet l’assemblage du ribosome au voisinage du codon d’initiation. Chez Arabidopsis thaliana, il existe à coté de la protéine eIF4E, une isoforme : eIF(iso)4E. Ces deux protéines participent à l’initiation de la traduction. L’existence de ces deux protéines évoque un phénomène de redondance fonctionnelle qui est attestée par la létalité du double mutant alors que les simples mutants sont viables. Cependant, l’étude phénotypique de mutants pour les gènes eIF4E et eIF(iso)4E a permis de montrer que cette redondance est partielle et inégale. En effet, les mutants pour le gène eIF4E présentent un retard de croissance, un retard de floraison, une baisse de la fertilité, une sénescence précoce et une activité traductionnelle réduite. Inversement, le phénotype des plantes mutantes pour le gène eIF(iso)4E est comparable à celui du sauvage. Les mutations dans les gènes eIF4E et eIF(iso)4E induisent une hypersensibilité à la lumière Enfin, en présence d’un inhibiteur de TOR la croissance de la racine des plantes de la lignée mutante pour le gène eIF(iso)4E est moins inhibée que celle des plantes de la lignée sauvage<br>More than 12 initiation factors are involved in eukaryotic translation initiation. The key step of this mechanism is the binding of eIF4E with the cap of the mRNA. This step allows the recruitment of the initiation complex and the assembly of the ribosome close to the start codon. Arabidopsis thaliana encodes a second eIF4E protein: eIF(iso)4E. Those two proteins perform translation initiation. The existence of those two proteins suggests that they may be functionally redundant. Double mutant lethality testifies for functional redundancy. However, phenotypic studies of mutant lines for gene eIF4E and eIF(iso)4E showed that redundancy is partial and unequal. Indeed, the eIF4E mutant lines exhibit growth delay in rosette and roots, bolting delay, impaired fertility and early senescence in leaves. Translational activity is also largely impaired. On the contrary, a mutant line for the eIF(iso)4E gene has the same phenotype as wild type line. Mutant lines for eIF4E and eIF(iso)4E are more sensitive to light and accumulate anthocyanins even in normal light. On the molecular level, the amounts of mRNA of genes that are involved in high light response and their association to polysomes increase. When plants are grown on media containing a TOR inhibitor, AZD-8055, plants of the eIF(iso)4E mutant line show less root growth inhibition compared to wild type and eIF4E mutant lines. This result suggests that eIF(iso)4E could be targeted by the TOR pathway
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Soleimanpour, Hamidreza, and Reza Zehtabchian. "Stakeholders analysis of Mashad House Manufacturing Factory." Thesis, Högskolan i Borås, Institutionen Ingenjörshögskolan, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-19890.
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Brown), (E Ashley Rogers. "Building a Better Mousetrap: Capturing New Data in ISI Journal Citation Reports and Local Journal Utilization Reports to Support Academic Collection Managers." Thesis, School of Information and Library Science, 2006. http://hdl.handle.net/1901/312.
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The ISI provides librarians with tools such as the Journal Citation Reports (JCR) and the institution specific Local Journal Utilization Report (LJUR) to aid in the management of serials collections. These tools enable librarians to respond quickly to changes in publishing practices and purchasing options. While available literature often criticizes ISI data, few studies provide concrete recommendations for improvement. This study explores two extensions to LJUR: (1) adding citation date and (2) creating institution specific impact factors. In addition, I explore the degree to which self-citations influence the ISI impact factor. Publication and citation calculations are made for three prominent southern universities’ research chemists using a corpus of full text articles drawn from 27 American Chemical Society (ACS) journals and stored in an Oracle database. The ACS research corpus impact factor simulation and ACS research corpus self-citation omission impact factor are also created and compared with current JCR data.
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Zyryanova, Alisa. "A molecule-inhibitor of the integrated stress response regulates activity of mammalian eukaryotic translation initiation factor 2B." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/284208.
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The Integrated Stress Response (ISR) is a conserved eukaryotic translational and transcriptional program implicated in mammalian metabolism, memory and immunity. Although mainly considered to be a protective mechanism, prolonged and severe ISR can result in cell death. The ISR is activated by diverse stress pathways converged on phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2) that inhibits the guanine nucleotide exchange activity of its partner eIF2B and attenuates overall rates of protein synthesis. Numerous mutations in eIF2B are linked to a fatal neurodegenerative disease of vanishing white matter. A new chemical inhibitor of the ISR (ISRIB), a bis-O-arylglycolamide, can reverse the attenuation of mRNA translation by phosphorylated eIF2 protecting mice from prion-induced neurodegeneration and traumatic brain injury. The work presented in this dissertation describes identification of mammalian eIF2B as a cellular target of ISRIB by implementing biochemical, biophysical, structural and chemogenetic methods. The herein reported cryo-electron microscopy-based structure of eIF2B uncovers a novel allosteric site on the translation factor capturing the ISRIB-binding pocket at the interface between its β and δ regulatory subunits. The extensive CRISPR/ Cas9-based screen for ISRIB-resistant and analogue-sensitive phenotypes revealed residues on the eIF2B dimer interface important for ISRIB binding. Based on the results reported in this dissertation along with the similar findings of others the potential molecular basis of ISRIB action, and its implication for the regulation of eIF2B's activity is broadly discussed. The identification of the ISRIB binding pocket away from the known interaction sites between eIF2B and eIF2 is also put into the context of a possible molecular mechanism of eIF2B's guanine exchange inhibition by phosphorylated eIF2. The work described in this dissertation provides new insight into the translational regulation and points to the importance of fine-tuning the activity of translation factors by small chemical molecules.
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Dai, Bin. "SIMULATIONS-GUIDED DESIGN OF PROCESS ANALYTICAL SENSOR USING MOLECULAR FACTOR COMPUTING." UKnowledge, 2007. http://uknowledge.uky.edu/gradschool_diss/483.
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Many areas of science now generate huge volumes of data that present visualization, modeling, and interpretation challenges. Methods for effectively representing the original data in a reduced coordinate space are therefore receiving much attention. The purpose of this research is to test the hypothesis that molecular computing of vectors for transformation matrices enables spectra to be represented in any arbitrary coordinate system. New coordinate systems are selected to reduce the dimensionality of the spectral hyperspace and simplify the mechanical/electrical/computational construction of a spectrometer. A novel integrated sensing and processing system, termed Molecular Factor Computing (MFC) based near infrared (NIR) spectrometer, is proposed in this dissertation. In an MFC -based NIR spectrometer, spectral features are encoded by the transmission spectrum of MFC filters which effectively compute the calibration function or the discriminant functions by weighing the signals received from a broad wavelength band. Compared with the conventional spectrometers, the novel NIR analyzer proposed in this work is orders of magnitude faster and more rugged than traditional spectroscopy instruments without sacrificing the accuracy that makes it an ideal analytical tool for process analysis. Two different MFC filter-generating algorithms are developed and tested for searching a near-infrared spectral library to select molecular filters for MFC-based spectroscopy. One using genetic algorithms coupled with predictive modeling methods to select MFC filters from a spectral library for quantitative prediction is firstly described. The second filter-generating algorithm designed to select MFC filters for qualitative classification purpose is then presented. The concept of molecular factor computing (MFC)-based predictive spectroscopy is demonstrated with quantitative analysis of ethanol-in-water mixtures in a MFC-based prototype instrument.
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Church, Donald Glen. "Reducing Error Rates in Intelligence, Surveillance, and Reconnaissance (ISR) Anomaly Detection via Information Presentation Optimization." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1452858183.
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Huang, Tian You, and 黃天佑. "Factors affecting ISO 9000 registration." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/70332293926425655665.
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Wang, Shu-Ching, and 王淑靜. "Customer Churning Factors in Broadband ISP Industry." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/42354065901116516315.
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碩士<br>國立臺北科技大學<br>商業自動化與管理研究所<br>92<br>In Taiwan, the broadband Internet access market has reached the saturation stage, with a penetration rate of 46.6% in April 2004. In addition, the lack of product differentiation was unable to create customer loyalty. As a result, high acquisition costs often cannot be recovered, as customers are frequently lured away by competitors’ attractive promotional packages or gifts. Of all the issues facing Broadband Internet Service Providers (BISP), they need to focus on sales and marketing, customer churn, content, and servicing policies. Therefore, how to offere differentiated and multiple services that meet customer needs and foster long-term customer relationship to reduce churn rate and enhance long-term profitability, has become a critical issue facing BISP’s.
This thesis will focus the discussion on the causes of customer churn. Utilizing Discriminant Analysis, Factor Analysis, and 1-Way ANOVA, and description statistical analysis to provide hypotheses and answers to the following two questions: the cause of customer churn, and customer behavior before and after churn, in order to provide guidance for developing retention and loyalty programs for the BISP.
The analyses revealed that there isn’t significant co-relation between churn pattern and population changes. The main causes of customer churn are service oriented or price oriented. For customers contemplating switching service providers, the main considerations are service oriented, price/package oriented, and product quality oriented. Varying emphasis of these three factors will affect the final selection of service provider.
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Lin, Lung-hua, and 林隆華. "Factors Affecting Performance After Obtaining ISO 14000 Certification." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/46949610737464727850.
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碩士<br>大同大學<br>事業經營研究所在職專班<br>90<br>ABSTRACT
While environmental protection and sustainable development have become the significant demand in global markets. Manufacturers are expected to become more environmentally responsible and environmentally conscious. The worldwide trend of environmental concern has been driving manufacturers to strive to implement competitive strategies in environmental management.
Upon the implementation of ISO 14000 quite a few countries not only utilize it as a measure of evaluation but also treat it as their own national standard. Nowadays ISO 14000 has already become a public standard for environmental management; meanwhile, certification promotion appears to be the common goal to which enterprises and governments have endeavored themselves to attain.
By means of combining all the comments from the literature review and consulting other specialists whom had experiences in assisting and guiding manufacturers to get ISO 14000 certification, this study has summed up 13 indicators of performance after obtaining ISO 14000 certification together with its 9 affecting factors. And regarded all the manufacturers who have got ISO 14000 certification in Taiwan as the sampling populations of this study to conduct empirical study. Canonical correlation analysis was adopted to analyze and identify the affecting factors that are significant to the performance after obtaining ISO 14000 certification.
Based on the canonical correlation analysis, this study found that the significant related affecting factors of performance after obtaining ISO 14000 certification involved: (1) The management’s continuous commitment (2) Continuous efforts made to improve environment after obtaining certification (3) Education and training given to the employees (4) Putting TQM into practice (5) Whether the implementation practices correspond to those listed in documents and (6) The company’s internal environmental management auditing activities.
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Reckhardt, Carsten, and carsten reckhardt@gmx de. "Factors influencing equal-loudness level contours." 2000. http://docserver.bis.uni-oldenburg.de/publikationen/dissertation/2001/recfac00/recfac00.html.
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Fang-Jen, LEE, and 李方仁. "AFFECTING FACTORS OF BUSINESS PERFORMANCE AFTER OBTAINING ISO 9000 CERTIFICATION." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/13516086053560253769.
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碩士<br>大同工學院<br>事業經營研究所<br>86<br>While competition in the business world is getting keener, product of a good quality gradually becomes the most sophisticated weapon used by competitors. The appeal for a good quality can no longer be made available through the channel of a single slogan; instead, it must be carried out by some concrete actions. Having the quality of their products approved by an international standard seems to be the most effective and public trustworthy action which can be taken by companies.Upon the implementation of ISO 9000 quite a few countries not only utilize it as a measure of evaluation but also treat it as their own national standard. Nowadays ISO 9000 has already become a public standard for quality control and quality assurance; meanwhile, certification promotion appears to be the common goal to which enterprises and governments have endeavored themselves to attain. By means of combining all the comments from the literature review and consulting other specialists whom had experiences in assisting and guiding manufacturers to get ISO 9000 certification, this study has summed up 14 indicators of performance after obtaining ISO 9000 certification together with its 9 affecting factors. And regarded all the manufacturers who have got ISO 9000 certification in Taiwan as the sampling populations of this study to conduct empirical study. Canonical correlation analysis was adopted to analyze and identify the affecting factors which are significant to the performance after obtaining ISO 9000 certification. Based on the canonical correlation analysis, this study found that the significant related affecting factors of performance after obtaining ISO 9000 certification involved: (1) Whether there are continuous efforts made to improve quality after obtaining certification (2) Putting TQM into practice or other quality control activities (3) Education and training given to the employees (4) Whether the operational practices correspond to those which listed in documents and (5) The company''s internal quality auditing activities.
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Chen, Yu-Kai, and 陳育凱. "The Study of Key Success Factors for ISP － Use AHP." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/89496857252597428313.
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碩士<br>中國文化大學<br>國際企業管理研究所<br>89<br>Internet is a prospective industry in decade. People who held “.com” dreams had already woke up. To welcome broad-bandwidth coming，we have to strive for thor-oughness to face the internet. Internet Service Provider (ISP) is a gatekeeper in this in-dustry. This study uses the Analytic Hierarchy Process (AHP) to discuss the key success factors for ISP.
The data is collected by 41 questionnaires through personal, telephone, email and mail interview. The subjects of this study are experts who are familiar with ISP. The to-tal questionnaires returned were 21 and one of them was unusable. Completed ques-tionnaires returned were 20 (48.8% response rate).
From this study we find all ISP firms consider the key success factors are as follows:
“Market Demand Factor”, “Customize Service”, “Competitive Behaviors between Rivals”, “Strategic Alliances between and beyond the Industry”, “Technical Factor ”, “Convenience of the Channel”, “Organization efficiency and the Abilities to adapt to the Changes”, “the Quality of Service Personnel”, “Policy and Regulations” and “Conduct Customer Relationship Management System”.
Finally, we summarize ten major findings which are: 1.“Market Shares” is more important than “Profit Margin”. 2.“Service Factor” and “Environment Factor” are im-portant to “Market Shares”. 3. “Environment Factor” and “Produce Process” are impor-tant to “Profit Margin”. 4.“Products combined with Specialty” and “Innovative Abili-ties” are important to “Produce Process”. 5. “Convenience of the Channel” and “Adver-tisements and Promotion” are important to “Marketing and Sale”. 6. “Customize Ser-vice” and “the Quality of Service Personnel” are important to “Service Factor”. 7.“Strategic Alliances between and beyond the Industry” and “Organization efficiency and the Abilities to adapt to the Changes” are important to “Enterprise Overall Policies”. 8. “Market Demand Factor” and “Competitive Behaviors between Rivals” are important to “Environment Factor”. 9.“Network Infrastructure ” is no more focus point to ISP firms. 10.Firms should pay more attentions to “Customers Privacy” and “Security”.
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Hsu, Chi-Ching, and 許其清. "Social Responsibility Key Factors Analysis For Enterprise Practicing ISO 26000." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/87955403101301723766.
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博士<br>國立臺北大學<br>企業管理學系<br>101<br>Social responsibility is a global concern, relevant to global social and economic development, also is an enterprise core strategy of sustainable development. This study is concerning about the characteristics of "ISO 26000:2010 - Guidance on Social Responsibility" analysis, and derive key issues and weights of social responsibility, providing reference to enterprises and organizations.
This study combined both qualitative and quantitative methods, first get expert group consensus by several Delphi interviews and surveys, then systematize complex social responsibility issues by analytic hierarchy process method. The conclusions are "Fair operating practices" as the most important core subject, others are environment, human rights, consumer, labor practices and so on, order by weight respectively.
In general, "Prevention of pollution" is the first important key issue when practice social responsibility, the second important key issue is "Protection of the environment, biodiversity and restoration of natural habitats", both of which are "environment" core subject issues. So, enterprises and natural resources are closely related, we must take care for the entire Earth's environment and pay attention to environment protection.
Many related researches and studies about social responsibilities till now, and with the legal and ethical relation directly or indirectly. ISO 26000 as the main scope in this study, suggest to subsequent research can be incorporated into other credible norms. Delphi method is an expert group decision-making, the number of experts, areas of expertise, as well as involvement may influence the results. Subsequent research can be increase experts interview and investigation within specific field. Research areas can be set up by research, interviews with experts invited investigation.
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DeBusk, Laura M. "Akt/IKK[alpha]/Vav1 signaling in endothelial cell survival and angiogenesis." Diss., 2008. http://etd.library.vanderbilt.edu/ETD-db/available/etd-03312008-163540/.
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Jau-Yih, Shiue, and 薛昭義. "The factors which influence "ISO-9000 standards"--The research on how to develop the organizational factors successfully." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/09667633778337044898.
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Hsueh, Pei-Fen, and 薛珮芬. "Critical Success Factors on Introducing ERP System－An Illustration with ISM." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/97442967218746060891.
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碩士<br>逢甲大學<br>會計所<br>98<br>ERP implementation have two-sided effects, a successful ERP implementation will help enterprises bring competitiveness, and otherwise it will cause a lot of waste. Most studies focus on exploring and collecting critical success factors when enterprise import ERP system, but they ignore the structural of critical success factors and the mental model of guider. The purpose of this research is try to find the structural model in critical success factors and the mental model of guider. The data collect were divided into two parts: the first part was collected 13 critical success factors from 47 success factors; the second part was collected Interpretive Structural Model questionnaire from 13experts. The results show that different interpretive structure model exist in different mental of guider, it means that guider play an important role when enterprise import ERP system.
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Chang, Ming-Lien, and 張明廉. "The Study on ISO 9000 or ISO 14000 Planning for the Military Factory of Integrated Maintenance." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/63780368806507591827.
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碩士<br>元智大學<br>機械工程研究所<br>88<br>Since the Army integrated maintenance factories were reorganized after the Military Force structure was rebuilt, the military logistic of supply and maintenance have been changed from maneuverable to localized in the operation area. For this reason, not only decrease the floating personnel, but also increase the maintenance capability by a wide margin. The operation should be merged with enterprise styles and perform within the policy of the Government and the global trend of development. Then it can carry out the standard approvals of ISO series.
This study discussed the practicality of ISO9000 or 14000 for the Military Factory of Integrated Maintenance. It was investigated according to the maintenance area layout and standard operating procedures of Lung-tan Military Factory, the influences of maintenance pollutions on the environment and noise damages from the equipment testing, also including the analyses on the manpower quality for maintenance. The results will improve the phenomenon, which are neglect of maintenance levels, lack of environmental protection on the field operations in the past, moreover, will popularize to give consideration to quality assurance, quality control and environmental protection policy. Not only we can strengthen the existing logistic and environmental protection policy to bring it into the national standard system, but also provide the personnel to work under a non-polluted environment to promote the image of the Military Force. In the meantime, this study can also be a reference of other units of the military and related enterprises in the Government.
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Teng, Chao-Jung, and 鄧朝榮. "The Phased Key Success Factors on the Military Body Obtains ISO 27001." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/95033605376238916009.
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碩士<br>中原大學<br>資訊管理研究所<br>97<br>ABSTRACT
In recent years, the blabbing secret of national defense occurred frequently, the accident of information security found constantly. The principal cause why department, which made the fault, unable to prevent from those threat is that the protection was executed singly. Where locks a whole plan to protect.
Someone who use the fast changing technology, Internet, to penetrate department, to damage information, and to steal secret. Those actions has been all-pervasive doing. Security of internet has become a battle of high-tech of internet generation. Military is the front of national security. So that security of information and communication was more important. In military, it cannot be ignored or evaded that how to set up an effective system, which was use to manage information and communication. ISO 27001 is the most complete information security management standards that was recognized by internationally. In this research, department of military, which is adopted certification of ISO 27001, was object of study. This thesis takes depth interview as major; documents of information security and literatures of ISO 27001 certification as subordinate for studying the key factors which influence the military department to adopt certification from ISO 27001.
In this study, we found the key factors for adopting certification in five stages:
Planning, educating, and training
The key factors are <high-order executive support and not promise>, <enterprise safe policies, goals, activities make clear>, <special project leader>, and <last advisor suitable information safety >.
Pondering of system and producing of documents
The key factors are <high-order executive support and not promise>, <suitable information safety last advisor>, and <degree not information-based >.
Trying, inner checking, and faults amending
The key factors are <high-order executive support and not promise>, <the staff are safe to information, and can't understand it assess risk, risk management acceptance and it accept it degree>, <audit and correct constantly>, and <complement by staff proper information safety education and training >.
Verifying and certification awarding
The key factors are <high-order executive support and not promise>, <is it can cooperate with suggestion of consultant firm to need>, coach a advisor by suitable information safety, and <are audit and correct constantly >.
Verifying constantly
The key factors are <high-order executive support and not promise>, it is safe in <enterprise policy, goal, activity make clear>, and <last advisor suitable information safety >.
It is for the reasons of limited time and inadequate resource that the object of study was chosen only one. The results of this research are able to be referred for the military agencies who want to obtain the certification of ISO 27001. The results also help to setup a safe information of environment which satisfied international standard. The final aim of this research is to guard against the accident of security information, to assure the safety of national defense information, and to destroy the opportunity of enemy attack.
Keyword：ISO 27001, Key Succeed
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Lai, Ming Kai, and 賴明楷. "Exploring Critical Success Factors of Organizations Implementing ISO 20000: a Case Study." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/76128569894401703077.
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碩士<br>長庚大學<br>資訊管理學研究所<br>97<br>Nowadays, IT service is still considered to fail in meeting the organizational needs, indicating that IT service can still be improved. IT Service Management (ITSM) has been proposed to improve the quality of IT service. More specifically, ITSM aims at a better management regards IT infrastructure to achieve the goals of organizations.
International Organization for Standardization (ISO) has published the ISO 20000 to evaluate ITSM Systems (ITSMS). To investigate critical success factors (CSFs) of organizations implementating ISO 20000, this study slects the cases which has abundant diccussions in related fields, codes the case descriptions and builds up an initial critical factors model based on three perspectives, that is, motivation, difficulties, and success respectively.
In this study, we interviewed the personnel of the organization which has been successful in qualifying ISO 20000 certification. The results were employed to create another critical factors model describing the experiences of the interviewed organization. The findings show that selecting cases containing abundant research data can benefit the research steps conducted in later steps. The results of our research are two factors that do not exist in the initial factor model: “using metrics to evaluate service quality (motivation)” and “the confidence to qualify certification (success)”. For the organizations which wish to obtain the certification in the future, this thesis provides some suggestions to help them smoothly implement ISO 20000.
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Gao, Da-Wei, and 高大惟. "Key Success Factors of Implementing ISO/IEC 27001: 2013 Information Security Management." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/xgx43e.
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碩士<br>國立臺北科技大學<br>管理學院EMBA華南專班<br>106<br>With very fast moving development of information technology and its wide applications, information system has become a very common facility for business information processing in organizations, and generating great service values and profits for organizations. Since organizations often use information system to process, transmit and store all the data and information; therefore, the information security management is an important management task for organization to avoid any possible damage or loss of money, credit or sudden interruption of operation caused by information security issue such as data or information to be falsified, leaked, erased, etc. ISO 27001 has been widely recognized and accepted as information security management standard. It is a standard of information security management mechanisms for providing organizations to identify the value and risk of their information assets. The aim of this study is starting from selection of ISO 27001 certified organizations as object of study, following with the expert interview questionnaire method to obtain the best hierarchical structure by using the 35 control categories of the 14 clauses of ISO 27001:2013, and use the analytical hierarchy process to summarize the key success factors for sharing such experience and giving a suggested direction to those organizations which are intending to implement ISO 27001 certification.
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Hu, Sheng-Min, and 胡聖珉. "THE IMPACT OF CRITICAL SUCCESS FACTORS FOR ISO 27001 CERTIFICATION ON PERFORMANCE." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/19892939747505587003.
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碩士<br>大同大學<br>事業經營學系(所)<br>97<br>In recent years, the internet has led to an increase in computer-dependent; enterprises are facing the competition from the globalization of electronic and information technology; in other words, the development of e-strategy and security policy needed to be conducted for reducing the security threats. So, the adoption of ISO 27001 is a hot topic in recent days. Therefore, this study focuses on identifying the critical success factors for implementing ISMS for enterprises and examining the impact of the critical success factors on performance.
In this study, we collect a total of 70 enterprises with adoption of ISO 27001 certification as valid samples to do statistical research. The results show that the adoption of ISO 27001 has a significant positive impact on performance, and the management dimension has the most influence of these four dimensions. But, external environment is relatively the smaller one. Also, enterprises with the implementation of ISO 27001 all have a positive impact on the BSC four perspectives of performance; it implies that the implementation of ISO 27001 has benefits on performance of the enterprise. Specifically, dimensions of critical factors all have positive impact on customers perspective. Secondly, management, technology dimensions have positive impact on financial perspective. Thirdly, management, technology and staff dimensions have positive impact on internal process perspective. Eventually, dimensions of critical factors all have positive impact on innovation and learning perspective.
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Wang, Jun-Min, and 王俊敏. "The Organized Factors Which Affect the Enterprisings Getting the Certification of ISO 14001." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/69633759447878848025.
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Lin, Yu-Chen, and 林宇溱. "The key success factors of implementing ISO 27001 in the information security policy." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/8a2wjy.
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碩士<br>中原大學<br>資訊管理研究所<br>103<br>In recent years, with the development of information technology and the popularity of internet, modern weapons systems have been gradually transformed into digitizing and networking. Nowadays the enemy we confront is no longer the tangible one, but the invisible hiding behind the internet. For Taiwan military, information safety is not only the protection of confidential information and data, but also related to the country security, so we cannot ignore the potential risk and danger.
The expert questionnaires of this study’s main objective is Taiwan military units who are successfully certificated by ISO 27001, and the study offers the critical success factors which influence the installation of ISO 27001 and the structure of the important assessment factors. Furthermore, the study releases questionnaires to every department of Taiwan military information security including some military units are not certificated, utilizing AHP (Analytic Hierarchy Process) to analyze these returned questionnaires, and then finding out the differences of all participants regarding the cognition of critical success factors.
According to the result of this research: (a) participants who have been certificated or not certificated all agreed that “the substance and environmental safety”, one of the 2nd level items, is the main critical success field which is successfully installed into ISO27001, and another 2 factors of the 3rd level items: “prevention from outside and environmental threats”, “cognition of information security, education and training” are the critical success factors successfully installed into the ISO27001; (b) the installation of ISO 270001 of the information security policy has been proven that it efficiently reduced the violation of information security events; (c) There are three hindrance that participants had when installing ISO 270001: superiors did not take it seriously, colleagues did not cooperate with each other and the expense was not enough.
To sum up, we expect that participants could put more emphasis on the importance of information security through this study, deeply understand the critical success factors and obstacles that participants might meet while implementing information security policy into ISO 27001, which could provide them with useful reference point; at the same time, it could be the future goal that every military unit get the ISO 270001 international standard certificate.
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Chou, Li-Wen, and 周俐彣. "Exploring the online shopping factors of cross-strait consumers : using ISM and ANP." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/54898509988684429405.
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碩士<br>國立勤益科技大學<br>流通管理系<br>103<br>With e-commerce booming, various industries get into this field to grasp the huge business opportunities; meanwhile, it draws a lot of attentions in academy, research topics cover broad range of issues and constantly updated, such as system technology, operating trends, marketing and advertising, customer relationship and so on. With the technology upgrading and competition even more intense, the online sales grew substantially on both area of Taiwan and China in recent years. There are numerous factors that affecting consumer intentions to go shop online, however, how different views cross-strait consumers hold? This study applies multiple-criteria decision-making (MCDM) methods, Interpretive Structural Model (ISM) and Analytical Network Process (ANP), to explore the difference and the dependent relationship between factors. It clarifies priorities and the importance weight to online shopping factors between cross-strait consumers. Last, this study will make recommendations for online operators to understand the relevant factors more and develop more effective business strategies.
This study collected data through questionnaires, gathering the views of the cross-strait consumers regarding online shopping factors. Analysis showed that the most important factor to cross-strait consumers is "transaction security"; even though technological advances increasingly, most consumers are still concerned for financial and privacy information involved in any online transaction. This highlights that online shopping platform and operators should keep in mind to devote more efforts on information protection and transaction security to get consumer trust. Overall, Taiwan's consumers consider factors more comprehensive in online transaction; the online operators must design shopping process with utmost care to enhance consumers’ shopping experience and satisfaction. On the other side, consumers in China pay more attentions to the trading professionalism. Last, this study presents two different relation structures of online shopping factors of Taiwan and China based on the analysis result; this helps business operators understand consumer demand, and further enhance the consumers’ willingness towards online shopping.
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Chen, Yu-Jung, and 陳玉容. "The Influencing Factors of ISD Team Creativity from the Perspective of Knowledge Management." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/20371530800693130782.
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碩士<br>南台科技大學<br>資訊管理系<br>98<br>This study focuses on the relationships between knowledge management and team creativity. Using hierarchical regression analysis, this study analyzes 43 teams. The results indicate that knowledge sharing and knowledge learning channel have significantly positive effects on knowledge transfer. Furthermore, it appears that knowledge transfer has significantly effect on teams’ creativity. The main overall practical implication that can be drawn from these findings is that to achieve high team creativity, team should to develop knowledge sharing, knowledge learning channel and knowledge transfer.
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Liu, Wei-Jyh, and 劉威志. "The Discount Division Of The Case Company To ImportThe ISO 27001 Key Success Factors." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/88075702467753964683.
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碩士<br>崑山科技大學<br>資訊管理研究所<br>100<br>This study hope that the case company integrated pilot units (hypermarkets, department) into the experience of ISO 27001, through expert interviews and the use of level analysis to determine the establishment of information security risk management systems (Information Security Management System, ISMS) all risk property factor to identifyimportant factor to the expectations of other departments of the case enterprises import operations, experience and suggestions direction. First of all, for import the ISO 27001 of the pilot unit to conduct the questionnaire survey, summed up the import ISO 27001 of the key factors and assessment framework, and then through the hierarchy analysis method (Analytic Hierarchy Process, AHP) analysis of each risk factor relative the right weight, By the risk factors of sort of exploring the great importance to the degree of ISO 27001. Expectations through the analysis of results of this study, as other departments of the case company to import the information security risk management system of decision-making reference to enhance the import of the effectiveness of information security management. The final study summed up the top five important risk attributes, as "evidence collection", "user password management, report information security incidents, organizational decision-makers practical support and network control operations, as other departments, the implementation of information security risk management reference.
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Chen, I.-Shao, and 陳奕劭. "The Study of Influence Factors and Benefits of Implement ISO 14000 Environmental Management System." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/35791920105961157871.
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碩士<br>大葉大學<br>工業工程與科技管理學系碩士在職專班<br>94<br>The objective of this study was to investigate the significance of environmental management and the key factors for ISO 14000 success and benefits. The questionnaire of this research was designed through referring documentation, collecting the ISO 14000 series certifications. Furthermore, the relevant factors had been extracted from the analysis results. With regards to the study range, questionnaires were mainly sent to the 178 firms in Taiwan, which login the website of Bureau of Commodity Inspection and Quarantine, and had acquired the certification of ISO 14001 by the end of Dec., 2005.
After finishing the questionnaire investigation, the data was analyzed by using factor analysis of SPSS software for extracting, reading, and naming the relevant factors. The following results have been obtained.
The motivation of companies for applying to the certification of ISO 14000 series could be divided into two major factors: “internal inducement” and “external inducement”.concerning the “perception importance” and “satisfaction” for the companies executing ISO 14000 environmental management systems; six key factors had been extracted out : (1)“rational monitoring and examination system”; (2)“the demand-orient of markets and customers”, (3)“educational training and continuous improvement”,(4) “participation and support from supervisor”, (5)“participation and identification of all staffs” and (6)“ the choice for counseling unit and certification institution”.As for the operation benefit of the companies after passing ISO 14000 certification, five factors had been extracted respectively as following: (1)“strengthen staffs’ conscious and skill toward environment”, (2)“resource thrift and recycling”, (3) “ improvement of production and administration performance”, (4) “risk reduction of products and operation ”, (5)“ relationship improvement with related party”.