Relevant bibliographies by topics / Isolated perfused working rat heart

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Isolated perfused working rat heart'

Author: Grafiati
Published: 4 June 2021
Last updated: 4 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Isolated perfused working rat heart.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Isolated perfused working rat heart"

1

Igić, Rajko. "The isolated perfused “working” rat heart: A new method." Journal of Pharmacological and Toxicological Methods 35, no. 2 (1996): 63–67. http://dx.doi.org/10.1016/1056-8719(96)00001-9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Zimmer, Heinz-Gerd. "The Isolated Perfused Heart and Its Pioneers." Physiology 13, no. 4 (1998): 203–10. http://dx.doi.org/10.1152/physiologyonline.1998.13.4.203.

Full text
Abstract:
In 1866, Carl Ludwig together with Elias Cyon created the first isolated perfused frog heart preparation. Perfusion systems for the isolated mammalian heart were developed by H. Newell Martin in 1883 and by Oscar Langendorff in 1895. In its working mode, the isolated perfused rat heart was established in the 1960s.
APA, Harvard, Vancouver, ISO, and other styles
3

Belke, Darrell D., Terje S. Larsen, Gary D. Lopaschuk, and David L. Severson. "Glucose and fatty acid metabolism in the isolated working mouse heart." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 277, no. 4 (1999): R1210—R1217. http://dx.doi.org/10.1152/ajpregu.1999.277.4.r1210.

Full text
Abstract:
Although isolated perfused mouse heart models have been developed to study mechanical function, energy substrate metabolism has not been examined despite the expectation that the metabolic rate for a heart from a small mammal should be increased. Consequently, glucose utilization (glycolysis, oxidation) and fatty acid oxidation were measured in isolated working mouse hearts perfused with radiolabeled substrates, 11 mM glucose, and either 0.4 or 1.2 mM palmitate. Heart rate, coronary flow, cardiac output, and cardiac power did not differ significantly between hearts perfused at 0.4 or 1.2 mM pa
APA, Harvard, Vancouver, ISO, and other styles
4

Dakin, Todd A., and R. William Currie. "Prior treatment with heat shock attenuates the stress response in isolated working rat hearts." Biochemistry and Cell Biology 73, no. 1-2 (1995): 31–39. http://dx.doi.org/10.1139/o95-004.

Full text
Abstract:
We examined the expression of the mRNAs encoding for the inducible heat shock protein (HSP) 71 and the constitutively synthesized HSP73 in control and 24-h post-heat-shocked (post-HS) hearts during isolated working heart perfusion. Paired control and 24-h post-HS rat hearts were perfused in the working heart mode for 1, 2, 3, or 4 h. Aortic and coronary flow rates and heart rates were not different between the control and 24-h post-HS hearts during the perfusion periods. After perfusion, total RN A was extracted and separated by gel electrophoresis. RNA was blotted to membranes, subsequently p
APA, Harvard, Vancouver, ISO, and other styles
5

Cohen, David M., Patrick H. Guthrie, Xiaolian Gao, Ryosei Sakai, and Heinrich Taegtmeyer. "Glutamine cycling in isolated working rat heart." American Journal of Physiology-Endocrinology and Metabolism 285, no. 6 (2003): E1312—E1316. http://dx.doi.org/10.1152/ajpendo.00539.2002.

Full text
Abstract:
To what extent does glutamine turnover keep pace with oxidative metabolism in the rat heart? To address this question, the following groups of substrates were presented to the isolated, working rat heart: 1) glucose (5 mM), insulin (40 μU/ml), and [2-13C]acetate (5 mM; high workload, n = 5); 2) pyruvate (2.5 mM) and [2-13C]acetate (5 mM; normal workload, n = 5); or 3) propionate (1 mM) and [2-13C]acetate (2.5 mM; normal workload, n = 3). In a subset of these experiments, the exchange of glutamate and glutamine was quantified by separation with ion exchange chromatography and analysis by GC-MS.
APA, Harvard, Vancouver, ISO, and other styles
6

Nicholl, T. A., G. D. Lopaschuk, and J. H. McNeill. "Effects of free fatty acids and dichloroacetate on isolated working diabetic rat heart." American Journal of Physiology-Heart and Circulatory Physiology 261, no. 4 (1991): H1053—H1059. http://dx.doi.org/10.1152/ajpheart.1991.261.4.h1053.

Full text
Abstract:
It is well established that cardiac dysfunction independent of atherosclerosis develops in both humans and animals with diabetes mellitus. The etiology is complex, involving many different processes, one of which may be increased fatty acid utilization and/or a concomitant decrease in glucose utilization by the diabetic heart. We compared control and 6-wk streptozotocin (STZ)-induced diabetic isolated working rat hearts and were able to demonstrate cardiac dysfunction in the diabetic as assessed by depressed heart rate (HR), heart rate peak systolic pressure product (HR.PSP), left ventricular
APA, Harvard, Vancouver, ISO, and other styles
7

Saddik, Maruf, and Gary D. Lopaschuk. "Triacylglycerol turnover in isolated working hearts of acutely diabetic rats." Canadian Journal of Physiology and Pharmacology 72, no. 10 (1994): 1110–19. http://dx.doi.org/10.1139/y94-157.

Full text
Abstract:
Although myocardial triacylglycerol may be a potentially important source of fatty acids for β-oxidation in diabetes, few studies have measured triacylglycerol turnover directly in hearts from diabetic animals. In this study, myocardial triacylglycerol turnover was directly measured in isolated working hearts from streptozotocin-induced acutely diabetic rats. Hearts were initially perfused in the presence of 1.2 mM [14C]palmitate and 11 mM glucose for 1 h (pulse) to label the endogenous lipid pools, followed by a 10-min washout perfusion. Hearts were then perfused for another hour (chase) with
APA, Harvard, Vancouver, ISO, and other styles
8

Walls, Joseph T., Todd L. Demmy, Jack J. Curtis, Race Kao, and Richard A. Schmaltz. "Load-Insensitive Measurements from an Isolated Perfused Biventricular Working Rat Heart." Journal of Biomedical Science 4, no. 2-3 (1997): 111–19. http://dx.doi.org/10.1159/000456973.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Demmy, Todd L., Jack J. Curtis, Race Kao, Richard A. Schmaltz, and Joseph T. Walls. "Load-insensitive measurements from an isolated perfused biventricular working rat heart." Journal of Biomedical Science 4, no. 2-3 (1997): 111–19. http://dx.doi.org/10.1007/bf02255601.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Russell, R. R., V. T. Nguyen, J. M. Mrus, and H. Taegtmeyer. "Fasting and lactate unmask insulin responsiveness in the isolated working rat heart." American Journal of Physiology-Endocrinology and Metabolism 263, no. 3 (1992): E556—E561. http://dx.doi.org/10.1152/ajpendo.1992.263.3.e556.

Full text
Abstract:
We have previously reported that the nutritional state in vivo results in differential insulin responses by the perfused heart in vitro. To further assess the effects of insulin on glucose uptake at physiological work loads, hearts from fed and fasted (16-20 h) rats were perfused with buffer containing 2-[18F]fluoro-2-deoxy-D-glucose (2-FDG) and glucose (10 mM) alone or plus lactate (10 mM) as a competing substrate, with insulin (10 mU/ml) added after a control period. When glucose was the only substrate, the addition of insulin decreased the fractional rate of 2-FDG uptake in hearts from eith
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Isolated perfused working rat heart"

1

Khan, Fatima. "Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8367_1256897201.

Full text
Abstract:
<p>&quot<br>An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic pressure, developed pressure, heart rate, cardiac work and coronary perfusion pressure in isolated rat hearts...&quot<br></p>
APA, Harvard, Vancouver, ISO, and other styles
2

Van, Vuuren Derick. "Postconditioning the isolated perfused rat heart : the role of kinases and phosphatases." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/20864.

Full text
Abstract:
Thesis (MScMed)--Stellenbosch University, 2008.<br>ENGLISH ABSTRACT: It has recently been observed that the application of multiple short cycles of reperfusion and ischaemia, at the onset of reperfusion, elicits cardioprotection against injury due to prior sustained ischaemia. This phenomenon has been termed “postconditioning” (postC) and is of special interest due to its clinical applicability. Although much work has been done to delineate the mechanism of protection, there is still controversy regarding the precise algorithm of postC, the importance of the reperfusion injury salvage kinases
APA, Harvard, Vancouver, ISO, and other styles
3

Edmunds, Nicholas J. "Actions of tumour necrosis factor-α in the rat isolated perfused heart". Thesis, University of Bath, 1998. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284400.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Keon, Claudia Anne. "Myocardial energy transduction in the isolated working rat heart." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244563.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Dean, David C. "Apoptosis in the isolated perfused rat heart, involvement of reperfusion, oxidants and protein synthesis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq26315.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Huang, Wei [Verfasser]. "Direct functional effects of opioid agonists on the isolated perfused rat heart / Wei Huang." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2013. http://d-nb.info/1037725727/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Obikeze, Kenechukwu. "Cardiovascular effects of Leonotis leonurus extracts in normotensive rats and in isolated perfused rat heart." Thesis, University of the Western Cape, 2004. http://etd.uwc.ac.za/index.php?module=etd&amp.

Full text
Abstract:
This thesis discussed the cardiovascular effects of the aqueous leaf extract and a fraction of the methanol extract of Leonotis leonurus, a plant commonly used in traditional medicine in South Africa for the treatment of hypertension and other cardiac problems. The cardiovascular effects was tested on anaesthetized normotensive male Wistar rats and isolated perfused rat hearts.
APA, Harvard, Vancouver, ISO, and other styles
8

Manga-Manguiya, Edith Sylvie. "Signalling pathways involved in insulin cardioprotection : are they comparable in normoxic perfused isolated rat heart vs. ischaemia/reperfusion model?" Thesis, Stellenbosch : University of Stellenbosch, 2006. http://hdl.handle.net/10019.1/17380.

Full text
Abstract:
Thesis (MSc)--University of Stellenbosch, 2006.<br>ENGLISH ABSTRACT: Introduction: It is well documented that insulin offers cardioprotection against the consequences of ischaemia/reperfusion injury. Insulin-induced improvements in cardiac functions are widely investigated in models of ischaemia and reperfusion. It has been shown that many signalling pathways may be involved in the cardioprotection properties of insulin under those conditions. These pathways include PI3-K, PKB/Akt, p70S6k, ERK and many others. However, little data exists on the effects of insulin on the heart under norm
APA, Harvard, Vancouver, ISO, and other styles
9

Nyepetsi, Naledi Gape. "Effects of dietary Garcinia kola supplementation and oxidative stress in isolated perfused rat hearts." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/1458.

Full text
Abstract:
Thesis submitted in fulfilment of the requirements for the degree of Master of Technology: Biomedical Technology In the Faculty of Health and Wellness Sciences At the Cape Peninsula University of Technology Supervisors: Prof. Adriaan J Esterhuyse Dr Dirk J Bester Bellville January 2014<br>Background: Oxidative stress and chronic inflammation contributes significantly to the pathogenesis of several ischaemic heart diseases, including atherosclerotic plaque rupture and myocardial infarction. It is widely demonstrated that ischaemia, followed by reperfusion, results in alterations of the mitochon
APA, Harvard, Vancouver, ISO, and other styles
10

Nicholl, Tessa Anne. "Effect of free fatty acids and dichloroacetic acid on the diabetic isolated working rat heart." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29641.

Full text
Abstract:
It is well established that a cardiomyopathy independent of atherosclerosis develops in both humans and animals with diabetes mellitus. The etiology of diabetic cardiomyopathy is very complex involving many different processes, one of which may be the increased fatty acid utilization, and/or the concomitant decrease in glucose utilization, by the diabetic heart. We compared control and 6-week streptozotocin(STZ)-induced diabetic isolated working rat hearts and were able to demonstrate cardiac dysfunction in the diabetic as assessed by depressed heart rate (HR), heart rate peak systolic pressur
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Isolated perfused working rat heart"

1

Legtenberg, Roger J., Ralph J. F. Houston, Paul Smits, and Berend Oeseburg. "Hemodynamic Changes Caused by Glibenclamide in Isolated, Working, Erythrocyte Perfused Rat Heart." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4717-4_31.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Olders, J., T. Boumans, J. Evers, and Z. Turek. "An Experimental Set-Up for the Blood Perfused Working Isolated Rat Heart." In Advances in Experimental Medicine and Biology. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-8181-5_20.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Olders, J., Z. Turek, J. Evers, L. Hoofd, B. Oeseburg, and F. Kreuzer. "Comparison of Tyrode and Blood Perfused Working Isolated Rat Hearts." In Advances in Experimental Medicine and Biology. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-8181-5_46.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Brandejs-Barry, Y., and B. Korecky. "Hemodynamic Performance of Creatine-Depleted Rat Heart in Isolated Blood-Perfused Working Preparation." In Developments in Cardiovascular Medicine. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-2053-1_27.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Legtenberg, Roger J., Ralph J. F. Houston, Paul Smits, and Berend Oeseburg. "Pinacidil-Induced Opening, Like Glibenclamide-Induced Closure of Cardiac KATP Channels, Protects Cardiac Function Against Ischemia in Isolated, Working, Erythrocyte Perfused Rat Hearts." In Oxygen Transport to Tissue XXIV. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0075-9_49.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Grover, Gary J., and Rajni Singh. "The Isolated, Perfused Pseudo-Working Heart Model." In Methods in Molecular Medicine™. Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-571-8_8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Cicutti, Nicholas, and Karel Rakusan. "Capillary Flow Direction In the Isolated Perfused Rat Heart." In Advances in Experimental Medicine and Biology. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2468-7_32.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Zbilut, Joseph P., Gottfried Mayer-Kress, Paul A. Sobotka, Michael O’Toole, and John X. Thomas. "Chaotic Heart Rate Dynamics in Isolated Perfused Rat Hearts." In Advanced Methods of Physiological System Modeling. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-9789-2_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Kehrer, James P., and Youngja Park. "Oxidative Stress during Hypoxia in Isolated-Perfused Rat Heart." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_36.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Hoch, Brigitte, Gudrun Lutsch, Wolfgang-Peter Schlegel, et al. "HSP25 in isolated perfused rat hearts: Localization and response to hyperthermia." In Biochemical Mechanisms in Heart Function. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-1279-6_30.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Isolated perfused working rat heart"

1

Dunn, M. E., A. E. Stanhewicz, T. G. Manfredi, A. C. Cosmas, R. L. Rodgers, and F. J. Vetter. "The isolated perfused working mouse heart system." In 2009 IEEE 35th Annual Northeast Bioengineering Conference. IEEE, 2009. http://dx.doi.org/10.1109/nebc.2009.4967760.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Hong-jiao Mao, Bao-ping Chen, Guang-yuan Ren, et al. "The Effects of Heptanol on Electrical Coupling during Ischemia in the Perfused Isolated Rat Heart." In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. IEEE, 2005. http://dx.doi.org/10.1109/iembs.2005.1616357.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Bao-ping Chen, Fang-yan Fan, Guang-yuan Ren, et al. "The Effects of &#954;-Opioid Receptor Stimulation on Electrical Coupling during Ischemia in the Perfused Isolated Rat Heart." In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. IEEE, 2005. http://dx.doi.org/10.1109/iembs.2005.1616358.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Giannessi, D., R. De Caterina, G. Lazzerini, R. Sicari, and P. Gazzetti. "RELATIVE SENSITIVITY OF CARDIAC PROSTACYCLIN AND THROMBOXANE TO INHIBITION BY NON-STEROIDAL ANTIINFLAMMATORY DRUGS IN THE RAT HEART." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643390.

Full text
Abstract:
We have previously shown that the isolated perfused rat Langendorff heart is able to synthesize detectable amounts of thromboxane (TX) A2, as well as prostacyclin (PGI2). Eicosanoid production in this system is increased during post-ischemic reperfusion, reflecting greater availability of substrate and net increase of synthesis. We assessed relative sensitivity of cyclooxygenases synthesizing TX and prostacyclin (probably located in different cell types) to aspirin (0.1, 0.5, 1 g/1), ibuprofen (1, 10, 80, 160, 320 mg/1) and diclofenac (0.01, 0.1, 0.5, 2.5, 5, 10, 25 mg/1), by radioimmunoassays
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Isolated perfused working rat heart' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography