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Relevant bibliographies by topics / Isolated perfused working rat heart / Dissertations / Theses

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Dissertations / Theses on the topic 'Isolated perfused working rat heart'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Khan, Fatima. "Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8367_1256897201.

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<p>&quot<br>An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic pressure, developed pressure, heart rate, cardiac work and coronary perfusion pressure in isolated rat hearts...&quot<br></p>

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2

Van, Vuuren Derick. "Postconditioning the isolated perfused rat heart : the role of kinases and phosphatases." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/20864.

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Thesis (MScMed)--Stellenbosch University, 2008.<br>ENGLISH ABSTRACT: It has recently been observed that the application of multiple short cycles of reperfusion and ischaemia, at the onset of reperfusion, elicits cardioprotection against injury due to prior sustained ischaemia. This phenomenon has been termed “postconditioning” (postC) and is of special interest due to its clinical applicability. Although much work has been done to delineate the mechanism of protection, there is still controversy regarding the precise algorithm of postC, the importance of the reperfusion injury salvage kinases

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3

Edmunds, Nicholas J. "Actions of tumour necrosis factor-α in the rat isolated perfused heart". Thesis, University of Bath, 1998. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284400.

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4

Keon, Claudia Anne. "Myocardial energy transduction in the isolated working rat heart." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244563.

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5

Dean, David C. "Apoptosis in the isolated perfused rat heart, involvement of reperfusion, oxidants and protein synthesis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq26315.pdf.

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6

Huang, Wei [Verfasser]. "Direct functional effects of opioid agonists on the isolated perfused rat heart / Wei Huang." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2013. http://d-nb.info/1037725727/34.

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7

Obikeze, Kenechukwu. "Cardiovascular effects of Leonotis leonurus extracts in normotensive rats and in isolated perfused rat heart." Thesis, University of the Western Cape, 2004. http://etd.uwc.ac.za/index.php?module=etd&amp.

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This thesis discussed the cardiovascular effects of the aqueous leaf extract and a fraction of the methanol extract of Leonotis leonurus, a plant commonly used in traditional medicine in South Africa for the treatment of hypertension and other cardiac problems. The cardiovascular effects was tested on anaesthetized normotensive male Wistar rats and isolated perfused rat hearts.

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8

Manga-Manguiya, Edith Sylvie. "Signalling pathways involved in insulin cardioprotection : are they comparable in normoxic perfused isolated rat heart vs. ischaemia/reperfusion model?" Thesis, Stellenbosch : University of Stellenbosch, 2006. http://hdl.handle.net/10019.1/17380.

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Thesis (MSc)--University of Stellenbosch, 2006.<br>ENGLISH ABSTRACT: Introduction: It is well documented that insulin offers cardioprotection against the consequences of ischaemia/reperfusion injury. Insulin-induced improvements in cardiac functions are widely investigated in models of ischaemia and reperfusion. It has been shown that many signalling pathways may be involved in the cardioprotection properties of insulin under those conditions. These pathways include PI3-K, PKB/Akt, p70S6k, ERK and many others. However, little data exists on the effects of insulin on the heart under norm

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9

Nyepetsi, Naledi Gape. "Effects of dietary Garcinia kola supplementation and oxidative stress in isolated perfused rat hearts." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/1458.

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Thesis submitted in fulfilment of the requirements for the degree of Master of Technology: Biomedical Technology In the Faculty of Health and Wellness Sciences At the Cape Peninsula University of Technology Supervisors: Prof. Adriaan J Esterhuyse Dr Dirk J Bester Bellville January 2014<br>Background: Oxidative stress and chronic inflammation contributes significantly to the pathogenesis of several ischaemic heart diseases, including atherosclerotic plaque rupture and myocardial infarction. It is widely demonstrated that ischaemia, followed by reperfusion, results in alterations of the mitochon

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10

Nicholl, Tessa Anne. "Effect of free fatty acids and dichloroacetic acid on the diabetic isolated working rat heart." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29641.

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It is well established that a cardiomyopathy independent of atherosclerosis develops in both humans and animals with diabetes mellitus. The etiology of diabetic cardiomyopathy is very complex involving many different processes, one of which may be the increased fatty acid utilization, and/or the concomitant decrease in glucose utilization, by the diabetic heart. We compared control and 6-week streptozotocin(STZ)-induced diabetic isolated working rat hearts and were able to demonstrate cardiac dysfunction in the diabetic as assessed by depressed heart rate (HR), heart rate peak systolic pressur

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11

Wilson, Craig Alan. "The effects of physiological estrogen replacement on the recovery of contractile function and energy metabolism following ischemia in the isolated working rat heart." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0016/MQ47114.pdf.

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12

Bester, Dirk Jacobus. "The effect of red palm oil supplementation of an oxidative risk induced diet and a high saturated fat diet on ischaemia/perfusion injury in the isolated perfused rat heart." Thesis, Cape Peninsula University of Technology, 2006. http://hdl.handle.net/20.500.11838/1470.

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Thesis (MTech (Biomedical Technology))--Cape Peninsula University of Technology, 2006<br>Research has shown that the activation of the NO-cGMP pathway leads to myocardial protection from oxidative stress conditions, such as ischaemia and reperfusion. Few of these studies have however combined diet induced oxidative stress with ischaemia/reperfusion injury. Although little is known about the effects of supplements such as red palm oil (RPO) on the NO-cGMP pathway, research has shown that dietary RPO-supplementation improved reperfusion aortic output recovery through mechanisms that

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13

Sanjak, Mohammed Salih. "The effect of physical exercise training on carnitine content and cardiac function of the isolated perfused working rat heart." 1985. http://catalog.hathitrust.org/api/volumes/oclc/13182319.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1985.<br>Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 89-105).

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14

"Rapid recovery of myocardial adenine nucleotides and performance in postischemic isolated perfused working rat heart by substrates supplement and concanavalin administration (atp, ischemia, ribose)." Tulane University, 1986.

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The research project dealt with the factors which limit the recovery of cardiac function following a moderate normothermic ischemia. The major findings were that, ischemia caused drastic degradation of myocardial high energy phosphate compounds, and the accumulated adenine nucleosides were washed out by the reperfusion of coronary system, resulting in postischemic myocardial low ATP levels and mechanical dysfunction. The lack of precursors of adenine nucleotides and the presence of a futile cycle, which converted AMP synthesized from salvage pathway and IMP synthesized from De novo pathway to

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15

Leadley, Robert Joseph. "A blood-perfused, supported, isolated rat heart system for coronary hyperperfusion studies." 1985. http://catalog.hathitrust.org/api/volumes/oclc/12532193.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 1985.<br>Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 22-24).

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16

Raffel, David Michael. "In vivo receptor pharmacology studies with [beta]-adrenergic receptors in isolated perfused rat heart." 1991. http://catalog.hathitrust.org/api/volumes/oclc/25683261.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1991.<br>Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 214-219).

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17

Smith, Tracy. "Comparison of the effects of docosahexaenoic acid and palmitic acid on ischemia reperfusion injury using an isolated perfused rat heart." Thesis, 2012. http://hdl.handle.net/10012/6499.

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Dietary docosahexaenoic acid (22:6n-3, DHA) has been shown to exert beneficial effects on coronary heart disease including the prevention of ischemia reperfusion injury. The ability to acutely infuse DHA to the heart to prevent ischemia reperfusion injury is a potentialy valuable tool in planned surgery where reperfusion and/or ischemia will take place including coronary artery bypass surgery and angioplasty. In the present study, hearts from chow-fed (AIN-93M) Sprague Dawley rats (male) 9-12 weeks of age were isolated and artificially perfused. The protocol included: 30 min stabilization pe

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18

Sermsappasuk, Pakawadee [Verfasser]. "Modeling of cardiac uptake, binding kinetics and inotropic response of amidarone, verapamil and α_tn1-adrenergic [alpha 1-adrenergic] agents in isolated perfused rat heart / von Pakawadee Sermsappasuk". 2007. http://d-nb.info/990741494/34.

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