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Relevant bibliographies by topics / Isolation of alkaloids

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Academic literature on the topic 'Isolation of alkaloids'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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Journal articles on the topic "Isolation of alkaloids"

1

Han, Sunkyu, Sangbin Jeon, and Joonoh Park. "Syntheses of Dimeric Securinega Alkaloids." Synlett 28, no. 18 (2017): 2353–59. http://dx.doi.org/10.1055/s-0036-1590864.

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The isolation of flueggenines A and B by Yue and co-workers in 2006 has triggered a burst of isolation reports of dimeric and oligomeric securinega alkaloid natural products. The compelling molecular structures of these compounds with various modes of connection between monomeric securinega units have posed intriguing challenges to the synthetic organic community. Herein, we have categorized high-order securinega alkaloids based on their biosynthetic mode of dimerization or oligomerization. We then have compiled all reported syntheses of dimeric securinega alkaloids based on our classification

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2

Nikolic, Milan, and Sinisa Djordjevic. "Alkaloids in the pharmaceutical industry: Structure, isolation and application." Chemical Industry 57, no. 10 (2003): 471–78. http://dx.doi.org/10.2298/hemind0310471n.

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By the end of the 18th and the beginning of the 19th century a new era began in medicine, pharmaceutics and chemistry that was strongly connected with alkaloids and alkaloid drugs. Even before that it was known that certain drugs administered in limited doses were medicines, and toxic if taken in larger doses (opium, coke leaves, belladonna roots, monkshood tubers crocus or hemlock seeds). However, the identification, isolation and structural characterization of the active ingredients of the alkaloid drugs was only possible in the mid 20th century by the use of modern extraction equipment and

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Kumari, Babita, and Hitesh Solanki. "Isolation of Alkaloids, Saponins and Tannins from Plants." INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT 5, no. 03 (2019): 223–25. http://dx.doi.org/10.18811/ijpen.v5i03.13.

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Current study involves the detection and estimation of alkaloids, saponins and tannins in the 3 plant species vis., Oxalis debilis, Chenopodium vulvaria and Malva neglecta were taken as sample study. All the selected plant samples were brought to the labortary of university and were oven dried at 70°C. Following standard method of Eluyode and Alabithe, detection and estimation of alkaloid, saponin and tannin was carried out. The results showed variation in all the plant species of 3 families containing different concentration of alkaloids, saponins and tannins. The study symbolise the variatio

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Hadjiakhondí, Abbas, Esmail Sodat Ebrahimi, Maryam Aboosaber, and Leila Safarian. "Isolation and characterization of alkaloids from thalictrum minus." LAPLAGE EM REVISTA 7, Extra-D (2021): 600–604. http://dx.doi.org/10.24115/s2446-622020217extra-d1143p.600-604.

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The aim of the present work was to continue studies on the alkaloid content of the minus and identifying major alkaloids of the above ground parts of Th. minus of Iranian origin. Thalictrum minus population of Iran, contained two major phenanthrene alkaloids that their structure were established by spectral methods. Thaliglucine has been detected for the first time in the minus. Thaliglucine N-oxide is assumed to be a new phenanthrene N-oxide.

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Ayer, William A., and Gertrude C. Kasitu. "Some new Lycopodium alkaloids." Canadian Journal of Chemistry 67, no. 6 (1989): 1077–86. http://dx.doi.org/10.1139/v89-163.

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The alkaloids of the club moss Lycopodiumobscurum L., collected in Northern Alberta, have been investigated. The known alkaloids lycopodine, lycodine, clavolonine, dihydrolycopodine, O-acetyldehydrolycopodine, flabelliformine, β-lofoline, lycofoline, and des-N-methyl-α-obscurine were isolated and identified, as were the known compounds des-N-methyl-β-obscurine and acrifolinol. α-Obscurine and β-obscurine were not detected. The structures of the previously unreported alkaloids hydroxypropyllycodine (9a), lyconnotinol (11a), lobscurinol (19a), epilobscurinol (19b), and acetyllobscurinol (19c) ar

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6

Wu, Jing, Bing-Jie Zhang, Wen-Na Xiao, Mei-Fen Bao, and Xiang-Hai Cai. "Alkaloids from the flower of Erythrina arborescens." RSC Advances 7, no. 81 (2017): 51245–51. http://dx.doi.org/10.1039/c7ra10827c.

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7

Jitsuno, Maki, Akihito Yokosuka, Ken Hashimoto, Osamu Amano, Hiroshi Sakagami, and Yoshihiro Mimaki. "Chemical Constituents of Lycoris albiflora and their Cytotoxic Activities." Natural Product Communications 6, no. 2 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600208.

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An alcoholic extract of Lycoris albiflora (Amaryllidaceae) showed potent cytotoxic activity against HL-60 cells with an IC50 value of 1.7 μg/mL. Phytochemical examination of the extract resulted in the isolation of 15 alkaloids, including two phenanthridine-type alkaloids (1, 2), one benzylphenethylamine-type alkaloid (3), two crinane-type alkaloids (4, 5), one pyrrolophenanthridine-type alkaloid (6), six lycorenan-type alkaloids (7–12), and three galanthamine-type alkaloids (13–15), together with three neolignans (16–18), two flavans (19, 20), and two acetophenone derivatives (21, 22). Compou

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Sastraruji, Thanapat, Araya Jatisatienr, Kritchaya Issakul, et al. "Phytochemical Studies on Stemona Plants: Isolation of New Tuberostemonine and Stemofoline Alkaloids." Natural Product Communications 1, no. 10 (2006): 1934578X0600101. http://dx.doi.org/10.1177/1934578x0600101001.

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Two new tuberostemonine alkaloids, tuberostemonine L (3) and tuberostemonine M (4) and a new stemofoline alkaloid, (3′S)-hydroxystemofoline (5), along with two known alkaloids, (2′S)-hydroxystemofoline (1) and neotuberostemonine (2) have been isolated from a root extract of an unidentified Stemona species (Stemona sp.). The structure and relative configuration of these new alkaloids has been determined by spectral data interpretation, while the 3′S configuration of 5 was determined from NMR analysis of its (R)- and (S)-Mosher esters.

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van Rensburg, Elmarie, Pieter C. Zietsman, Susan L. Bonnet, and Anke Wilhelm. "Alkaloids from the Bulbs of Boophone disticha." Natural Product Communications 12, no. 9 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200911.

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Boophone disticha is widely used in South African traditional medicine. Several of its biological properties can be corroborated via its alkaloid constituents. Previous research on this plant led to the isolation of several alkaloids, mainly of the crinane alkaloid group of the Amaryllidaceae. In the present study, one new compound 1- O-acetylbuphanamine (1) and four known crinane alkaloids were isolated chromatographically from the ethanol extract of the bulbs of B. disticha. Their structures were determined via spectroscopic methods, including 1D and 2D NMR, ESI-MS, HRMS and IR data.

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Janeš, Damjan, Boštjan Kalamar, and Samo Kreft. "Improved Method for Isolation of Lycopsamine from Roots of Comfrey (Symphytum officinale)." Natural Product Communications 7, no. 7 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700713.

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An improved method for the isolation and purification of pyrrolizidine alkaloids from comfrey ( Symphytum officinale L.) roots was developed, introducing very fast, selective and ion residue-free reduction of N-oxides followed by ion-exchange chromatography giving a non-aqueous solution of alkaloids, from which solvents can be easily removed. With this procedure the use of large volumes of organic solvents, very slow reduction of N-oxides and input of additional impurities was avoided. Lycopsamine, which proved to be the major alkaloid, was additionally purified by preparative layer chromatogr

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Dissertations / Theses on the topic "Isolation of alkaloids"

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Burke, Edmund William Dwerryhouse. "Isolation, identification and chemical modification of Narcissus alkaloids." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/isolation-identification-and-chemical-modification-of-narcissus-alkaloids(7fcf6ef2-c9da-4760-89ac-d275433e66dc).html.

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Galanthamine is one of only a few drugs that is licenced for the treatment of Alzheimer's disease. It is manufactured through an inefficient synthetic process or extracted from members of the Amaryllidaceae plant family. In this work a range of structurally related alkaloids was semisynthesised from galanthamine and used as standards to assist with the search for alkaloids that may make a good starting point in the semisynthesis of galanthamine. The search was targeted on the effluent from the production line of Alzeim Ltd., a company that extracted galanthamine from members of the Narcissus g

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Asibal, Clarita Florendo. "Isolation and structural elucidation of pyrrolizidine alkaloids from four plant sources." Diss., Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/30246.

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3

Mianda, Mutombo Sephora. "Isolation of antiplasmodial naphthylisoquinoline alkaloids from Ancistrocladus sp. through bioassay-guided fractionation." Diss., University of Pretoria, 2019. http://hdl.handle.net/2263/77853.

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Ancistrocladus is the only genus in the Ancistrocladaceae family and together with the closely related Dioncophyllaceae, they produce naphthylisoquinoline (NIQ) alkaloids. This class of compounds exhibits a very interesting large spectrum of bioactivities. Some of these compounds have shown very promising antiplasmodial activity. Leaves of an as yet unidentified Ancistrocladus sp collected in the region of Bonsolerive (Northwestern part of DRC), were investigated for their antiplasmodial activity. They were air dried at room temperature and ground. The ground plant material was extracted seque

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Bonetti, Sandra J. "Studies on the isolation and biotransformation of pyrrolizidine alkaloids and related bioactive compounds." Diss., Georgia Institute of Technology, 1988. http://hdl.handle.net/1853/30244.

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Elsheikh, Mahammed Osman Abdalla. "Isolation, identification and structural elucidation of tertiary alkaloids from the root of Thalictrum minus L. race C /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487262825077916.

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Purwanto. "Isolation and characterization of novel O-methyltransferase involved in benzylisoquinoline alkaloids biosynthesis in Eschscholzia californica." Kyoto University, 2017. http://hdl.handle.net/2433/228255.

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Bapela, Mahwahwatse Johanna. "Nmr-based metabolomic study of medicinal plants used against malaria and the isolation of bioactive alkaloids." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/53513.

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Despite the significant advances achieved in lessening the burden of malaria and other tropical diseases in recent years, protozoal infections remain a major cause of mortality in many developing countries, with malaria accounting for a large proportion of the recorded mortality. The main aim of this study was to bioprospect indigenous plant species for novel antiplasmodial plant products by means of NMRbased metabolomics. In this study, an ethnobotanical criterion was followed in collecting twenty indigenous plant species used to treat malaria or its symptoms by Vha-Venda people livin

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8

Seaf, Shaimaa Fayez Ali Mohammed [Verfasser], and Gerhard [Gutachter] Bringmann. "Isolation, structural elucidation, and biological evaluation of Naphthylisoquinoline alkaloids from two African Ancistrocladus species / Shaimaa Fayez Ali Mohammed Seaf ; Gutachter: Gerhard Bringmann." Würzburg : Universität Würzburg, 2019. http://d-nb.info/1200355431/34.

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9

Eriksson, Carina. "Isolation, Synthesis and Structure-Activity Relationships of Antifeedants against the Pine Weevil, Hylobius Abietis." Doctoral thesis, Stockholm Chemical Science and Engineering, KTH, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3919.

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Adou, Eba. "I. Isolation and Characterization of Bioactive Compounds From Suriname and Madagascar flora. II. A Synthetic Approach to Lucilactaene." Diss., Virginia Tech, 2005. http://hdl.handle.net/10919/29973.

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As part of an International Cooperative Biodiversity Group (ICBG), extracts of plants from Suriname and Madagascar were bioassayed for cytotoxicity and antimalarial activity. Six cytotoxic extracts and one potential antimalarial were selected for fractionation, and yielded a number of bioactive compounds which were characterized by spectroscopy methods. Craspidospermum verticillatum (Apocynaceae) yielded four known indole alkoids. Casimirella sp (Icacinaceae) gave three new and five known diterpenoids. Pentopetia androsaemifolia (Apocynaceae) afforded one new and three known cardenolide glycos

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Books on the topic "Isolation of alkaloids"

1

Fattorusso, Ernesto, and Orazio Taglialatela-Scafati. Modern Alkaloids: Structure, Isolation, Synthesis, and Biology. Wiley & Sons, Limited, John, 2007.

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Fattorusso, Ernesto, and Orazio Taglialatela-Scafati. Modern Alkaloids: Structure, Isolation, Synthesis, and Biology. Wiley & Sons, Incorporated, John, 2008.

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Modern alkaloids: Structure, isolation, synthesis and biology. Wiley-VCH, 2008.

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(Editor), Ernesto Fattorusso, and Orazio Taglialatela-Scafati (Editor), eds. Modern Alkaloids: Structure, Isolation, Synthesis and Biology. Wiley-VCH, 2007.

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Book chapters on the topic "Isolation of alkaloids"

1

Kitajima, Mariko, and Hiromitsu Takayama. "Lycopodium Alkaloids: Isolation and Asymmetric Synthesis." In Topics in Current Chemistry. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/128_2011_126.

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Wangchuk, Phurpa. "Plant Alkaloids: Classification, Isolation, and Drug Development." In Medicinal Plants. CRC Press, 2019. http://dx.doi.org/10.1201/9780429259968-10.

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Schaeffer, Steven T., Leon H. Zalkow, and Amyn S. Teja. "Extraction and Isolation of Chemotherapeutic Pyrrolizidine Alkaloids from Plant Substrates." In ACS Symposium Series. American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0406.ch026.

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4

Verpoorte, R., and J. Schripsema. "Isolation, Identification, and Structure Elucidation of Alkaloids A General Overview." In Modern Methods of Plant Analysis. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-84226-9_1.

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5

Zhen, Jing, Cara Welch, Yue Guo, et al. "Novel Skeleton Flavan-Alkaloids from African Herb Tea Kinkéliba: Isolation, Characterization, Semisynthesis, and Bioactivities." In ACS Symposium Series. American Chemical Society, 2020. http://dx.doi.org/10.1021/bk-2020-1361.ch016.

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6

Endt, Débora Vom, and Giancarlo Pasquali. "Isolation of Proteins Binding to Promoter Elements of Alkaloid Metabolism-Related Genes Using Yeast One-Hybrid." In Plant Secondary Metabolism Engineering. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-723-5_5.

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Morrow, Gary W. "Biosynthesis of Alkaloids and Related Compounds." In Bioorganic Synthesis. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780199860531.003.0010.

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Though definitions may vary from source to source, the term alkaloid generally refers to members of a large set of naturally occurring, slightly basic (i.e., alkaline) nitrogen-containing organic compounds. Generally excluded from this group are amino acids, peptides, proteins, N-containing carbohydrates, and nitrogenous bases used in the construction of nucleotides. Though a small number are produced by animals or microorganisms, the vast majority of alkaloids are plant-produced compounds possessing a remarkably diverse range of structural features, from simple cycloaliphatic amines to highly complex polycyclic N-heterocycles. Some representative alkaloids are shown in Fig. 7.1. Alkaloid-containing plants and their extracts have been used by humans for thousands of years, mainly on the basis of their stimulant, therapeutic, or poisonous properties. References to plants containing compounds such as morphine (from opium poppies), strychnine (from seeds of the Strychnos nux-vomica tree), ephedrine (from the plant Ephedra chinensis), and coniine (from the poison hemlock plant) may be found in some of our earliest known writings. Today, it has been estimated that the health care of over 5 billion people worldwide benefits from the use of plant-based medicinal agents, many of which are alkaloids. With that in mind, it is worth noting concerns that deforestation, environmental damage, large-scale development, and unregulated harvesting programs may ultimately lead to the extinction of hundreds of known medicinal plants and perhaps even more whose medicinal properties have yet to be discovered, thereby endangering the prospects for future discoveries of new curative agents for the benefit of all humankind. As a scientific field, alkaloid chemistry itself dates back to the early 1800s with the first isolation of pure crystalline morphine from opium. This milestone achievement allowed the delivery of accurate, therapeutic doses of a drug that was immensely valuable for the relief of pain but which could also lead to fatal overdoses when administered from simple extracts of variable composition and strength. The subsequent rapid development of increasingly sophisticated techniques for the isolation and purification of the active components (often alkaloids) from many other medicinal plants essentially spawned the field of organic chemistry.

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Knölker, Hans-Joachim, and Kethiri R. Reddy. "Occurrence, Isolation, and Structure Elucidation." In The Alkaloids: Chemistry and Biology. Elsevier, 2008. http://dx.doi.org/10.1016/s1099-4831(07)00002-8.

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9

Leicach, Silvia, Hugo Chludil, and Margarita Grass. "Chromatography and Spectroscopy of Alkaloids." In Isolation, Identification and Characterization of Allelochemicals/ Natural Products. Science Publishers, 2009. http://dx.doi.org/10.1201/b10195-10.

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Ilkei, Viktor, László Hazai, Sándor Antus, and Hedvig Bölcskei. "Flavonoid Alkaloids: Isolation, Bioactivity, and Synthesis." In Studies in Natural Products Chemistry. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-444-64058-1.00008-x.

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Conference papers on the topic "Isolation of alkaloids"

1

Kaya, Gİ, K. Uzun, S. Demir, B. Bozkurt, MA Onur, and N. Unver Somer. "Isolation of further alkaloids from Galanthus cilicicus." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608244.

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Elusiyan, C., S. Akinyele, N. Omisore, and C. Adewunmi. "Molluscicidal and Antimalarial Properties and Isolation of Alkaloids from Crinum jagus (Thomps) Dandy." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608452.

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