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Journal articles on the topic 'Isopropyl myristate'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Rusli, Nirwati, Yulianti Fauziah, Selfyana austin Tee, Esti Badia, and Putri Nabila. "PENGARUH KONSENTRASI ISOPROPIL MIRISTAT SEBAGAI PENGIKAT SEDIAAN BLUSH ON STICK EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus)." Jurnal Analis Kesehatan Kendari 6, no. 2 (2024): 54–62. http://dx.doi.org/10.46356/jakk.v6i2.307.

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ABSTRACT Isopropyl myristate is a binder that is commonly used for blush forms because of its adhesive properties, Isopropyl myristate can distribute the particle size of the final preparation evenly and produce a smooth skin appearance. The use of isopropyl myristate as a binder for blush stick preparations is also very good at distributing the color of the blush. Blush On is cosmetic to blush or make the shape of the cheeks perfect, solid in shape. The purpose of this research was to see the effect of isopropyl myristate as a binder and to determine the optimal concentration of isopropyl myr

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Devendiran, Sundar Vankayala, Vijayalakshmi Rajendran, and Dhanaraju Magharla Dasaratha. "Novel Clarithromycin Loaded Self Emulsifying Drug Delivery System for Amplification of Solubility and Oral Bioavailability." Der Pharma Chemica 15, no. 4 (2023): 9. https://doi.org/10.5281/zenodo.13320267.

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SEDDS (self-emulsifying drug delivery system) are of particularly relevant for the production of isotropic mixtures of oil, surfactant, co-surfactant, and drug in order to solve their physicochemical problems. Clarithromycin (CLA), a macrolide, has a 50 percent absolute bioavailability. The goal of this work was to create a liquid SEDDS system for CLA in order to increase solubility by increasing interfacial surface area and thereby boosting absorption. Clarithromycin SEDDS were produced with isopropyl myristate as the oily phase, Cremophor EL, Tween 80, Brij 58 as surfactants, and isopropyl a

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3

Sundar, Vankayala Devendiran, Rajendran Vijayalakshmi, and Magharla Dasaratha Dhanaraju. "Novel Clarithromycin Loaded Self Emulsifying Drug Delivery System for Amplification of Solubility and Oral Bioavailability." DER PHARMA CHEMICA 15, no. 4 (2023): 9. https://doi.org/10.4172/0975-413X.15.4.5-13.

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SEDDS (self-emulsifying drug delivery system) are of particularly relevant for the production of isotropic mixtures of oil, surfactant, co-surfactant, and drug in order to solve their physicochemical problems. Clarithromycin (CLA), a macrolide, has a 50 percent absolute bioavailability. The goal of this work was to create a liquid SEDDS system for CLA in order to increase solubility by increasing interfacial surface area and thereby boosting absorption. Clarithromycin SEDDS were produced with isopropyl myristate as the oily phase, Cremophor EL, Tween 80, Brij 58 as surfactants, and isopropyl a

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4

Abdul, Rajab, Latif Melda, Imran Hamid Muhammad, and Uldira Septiyeni Tesya. "Monoesters for transformer insulating liquid." TELKOMNIKA (Telecommunication, Computing, Electronics and Control) 20, no. 6 (2022): 1384–92. https://doi.org/10.12928/telkomnika.v20i6.21870.

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The development of low viscosity insulating liquids derived from natural esters is conducted in our laboratory. Nine monoesters, i.e., methyl myristate, ethyl myristate, isopropyl myristate, methyl palmitate, ethyl palmitate, isopropyl palmitate, methyl stearate, ethyl stearate, and isopropyl stearate were synthesized from alcohols and saturated fatty acids. Treatments were performed to reduce water and acid contents and improve the oxidation stability of the monoesters. Some fundamental properties, such as breakdown voltage, kinematic viscosity, density, water content, acidity, and oxidation

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5

Abraham, Michael H., and William E. Acree. "Characterisation of the water–isopropyl myristate system." International Journal of Pharmaceutics 294, no. 1-2 (2005): 121–28. http://dx.doi.org/10.1016/j.ijpharm.2005.01.028.

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6

Aryani, Ni Luh Dewi, Siswandono Siswandono, Wdji Soeratri, Dian Yulyandani Putri, and Pingky Dwi Puspitasarini. "Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers." Journal of Pharmacy & Pharmacognosy Research 9, no. 5 (2021): 573–83. http://dx.doi.org/10.56499/jppres21.1038_9.5.573.

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Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers. Aims: To developed coenzyme Q10 nanostructured lipid carriers using myristic acid with various liquid lipids as lipid matrix by in vitro studies and in silico approach for explaining the interaction of coenzyme Q10-lipid at the molecular level. Methods: The coenzyme Q10 nanostructured lipid carriers were prepared using myristic acid as solid lipid with oleic acid, isoprop

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7

Malakar, Jadupati, Amit Kumar Nayak, and Aalok Basu. "Ondansetron HCl Microemulsions for Transdermal Delivery: Formulation and In Vitro Skin Permeation." ISRN Pharmaceutics 2012 (June 19, 2012): 1–6. http://dx.doi.org/10.5402/2012/428396.

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Ondansetron HCl delivery through oral route suffers due to its low bioavailability due to first-pass metabolism. Therefore, the microemulsion-based transdermal delivery may be a better substitute for it. The pseudoternary phase diagrams were constructed to determine compositions of microemulsions, and ondansetron HCl microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant evaluated for in vitro skin permeation through excised porcine skin. The in vitro skin permeation

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8

Hendriati, Lucia, Iwan Sahrial Hamid, Teguh Widodo, Regiskha Hermandanie Surya, Alif Ekacahya Wahyudi, and Dwi Damayanti Rasdianto. "ANALGESIC ACTIVITY OF TRANSDERMAL PATCH ETHANOL EXTRACT PIPER NIGRUM L FRUCTUS WITH SOME ENHANCERS ON MICE." Jurnal Farmasi Sains dan Praktis 7, no. 1 (2021): 67–73. http://dx.doi.org/10.31603/pharmacy.v7i1.4033.

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Piper nigrum L fructus with active compound piperin had been known have an analgesic effect. Ethanol extract of Piper nigrum formulated to transdermal patch to reduce side effect of analgesic oral. The aim of this research was to know the effect of sodium lauryl sulphate, Tween 80, isopropyl myristate as enhancer of transdermal patch ethanolic extract of Piper nigrum L. Analgesic effect of Piper nigrum L. carried out by writhing method after acetic acid induction in mice. Parameters used were the number of writhing and macrophage from peritoneal fluid of mice at the end of this study. Based on

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9

Nadia, Nadia. "FORMULASI SEDIAAN BLUSH ON DARI EKSTRAK KUBIS UNGU (Brassica Oleracea L. var. capitates f. rubra) SEBAGAI PEWARNA DALAM BENTUK COMPACT POWDER." Jurnal Penelitian Farmasi & Herbal 4, no. 2 (2022): 52–56. http://dx.doi.org/10.36656/jpfh.v4i2.861.

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Cosmetics have been known to humans since centuries ago. Since the last 40 years, cosmetics has grown rapidly. Quantias and the quality of biological materials for use on the skin are increasing. Blush on is created from attractive colors and of course using coloring agents. Purple cabbage extract is used as a dye in blush on with a concentration of 30% and Isopropyl myristate as a binder with various concentrations of 0.5%, 1.0% and 2.0%. Purple cabbage extract was obtained by 96% ethanol maceration, then filtered and rotary using a rotary evaporator, then evaporated in a water bath with a te

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10

Bharati, A., and C. M. King. "Allergic contact dermatitis from isohexadecane and isopropyl myristate." Contact Dermatitis 50, no. 4 (2004): 256–57. http://dx.doi.org/10.1111/j.0105-1873.2004.0301f.x.

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11

Fu, Yan, Yan Liu, Yu Fang, Xiaodan Qi, and Deying Cao. "Physicochemical Characterization of Lecithin/Isopropyl Myristate Reverse Micelles." ChemistrySelect 2, no. 24 (2017): 7439–44. http://dx.doi.org/10.1002/slct.201701174.

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12

Malakar, Jadupati, Suma Oomen Sen, Amit Kumar Nayak, and Kalyan Kumar Sen. "Development and Evaluation of Microemulsions for Transdermal Delivery of Insulin." ISRN Pharmaceutics 2011 (July 7, 2011): 1–7. http://dx.doi.org/10.5402/2011/780150.

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Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. The pseudoternary phase diagrams were constructed to determine the composition of microemulsions. The insulin permeation flux of microemulsions containing oleic acid as oil phase through excised mouse skin and goat skin was comparatively greater than that of microemulsions containing isopropyl myristate as oil phase. The insulin-loaded microemulsion containing 10% oleic acid, 38% aqueous phase, and

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13

Dhilasari, Estu Mahanani. "Pengaruh Penambahan Enhancer Isopropil Miristat dan dan Propilen Glikol terhadap Penetrasi Krim Asiklovir." Pharmaceutical and Biomedical Sciences Journal (PBSJ) 4, no. 1 (2022): 21–28. http://dx.doi.org/10.15408/pbsj.v4i1.25859.

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Acyclovir, a BCS class III drug, has a high ability to fight the herpes virus but has low permeability and is poorly soluble in water. In order to obtain the expected effect of viral infection on the skin, the penetration of the active ingredients becomes a critical factor for a topical treatment to achieve the desired concentration. This study was to see the effect of adding isopropyl myristate and propylene glycol as enhancers that help diffuse the drug through the stratum corneum. The formulation is made by adding enhancer propylene glycol 8% (F1), isopropyl myristate 8% (F2), and without e

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14

Tarigan, J. B., D. A. Barus, G. Brahmana, et al. "MICROWAVE FACILITATED THE SYNTHESIS OF ISOPROPYL MYRISTATE AND PALMITATE USING HETEROGENEOUS CATALYST." RASAYAN Journal of Chemistry 16, no. 01 (2023): 176–81. http://dx.doi.org/10.31788/rjc.2023.1618078.

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In the present research, a microwave-intensified esterification reaction of myristic acid and palmitic acid with isopropyl alcohol (IPA) to produce an emollient ester using Amberlyst46 as a catalyst was studied. The effect of the ratio of molar fatty acid to alcohol, catalyst weight, reaction time, and microwave power on isopropyl myristate (IPM) and isopropyl palmitate (IPP) conversion and yield were investigated systematically. The results showed that catalyst weight and microwave power significantly affect the conversion and yield of IPM and IPP, respectively. The maximum conversion and yie

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15

Thi Huong Hoa, Le, Vo Tran Ngoc Hung, Do Thu Trang, Thai Nguyen Hung Thu, and Dinh Chi Le. "Development and Validation of an HPLC Method for Simultaneous Assay of MCI and MI in Shampoos Containing Plant Extracts." International Journal of Analytical Chemistry 2019 (November 20, 2019): 1–10. http://dx.doi.org/10.1155/2019/1851796.

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A simple, easy-to-implement HPLC method was developed and validated for simultaneous determination of two isothiazolinone preservatives, methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI), in hair care shampoo containing plant extracts. In this method, shampoo samples were first dissolved in isopropyl myristate and then MCI and MI were extracted from isopropyl myristate layer by a mixture of methanol and 0.02 M phosphate buffer solution pH 3.0 (30: 70, v/v) and analyzed on an analytical biphenyl column maintained at 25°C with a mixture of methanol and water (10: 90, v/v) in isocr

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16

Song, Ming, Yuhan Xin, Sulan Cai, Weizhuo Xu, and Wei Xu. "Immobilized KDN Lipase on Macroporous Resin for Isopropyl Myristate Synthesis." Catalysts 13, no. 4 (2023): 772. http://dx.doi.org/10.3390/catal13040772.

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Free enzymes often face economic problems because of their non-repeatability and variability, which limit their application in industrial production. In this study, KDN lipase was immobilized with the macroporous resin LXTE-1000 and glutaraldehyde. The optimal conditions of enzyme immobilization were defined by a single factor experiment and response surface methodology (RSM). The concentration of the cross-linking agent glutaraldehyde was 0.46% (v/v), the cross-linking temperature was 25.0 °C, and the cross-linking time was 157 min. The enzyme activity of the immobilized KDN lipase after adso

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17

Mateus, V. C. Silva, A. P. de Souza Caio, C. de Oliveira Pedro, F. de Castro Heizir, and Freitas Larissa. "Isopropyl myristate continuous synthesis in a packed-bed reactor using lipase immobilized on magnetic polymer matrix." International Journal of Engineering Research & Science 4, no. 10 (2018): 12–20. https://doi.org/10.5281/zenodo.1474108.

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<strong><em>Abstract</em></strong><strong>—</strong> <em>The aim of this study was to synthesize isopropyl myristate, an emollient ester, in a continuous-flow packed-bed reactor using Candida antarctica lipase immobilized on poly(styrene-co-divinylbenzene) matrix prepared by suspension polymerization and magnetized by co-precipitation of Fe<sup>2+</sup> and Fe<sup>3+</sup> in alkaline medium. To determine the best esterification conditions, we investigated the effects of acid/alcohol molar ratio (1:5, 1:10, and 1:15) on reaction yield in shake flasks. The three tested conditions provided

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18

Uter, Wolfgang, Axel Schnuch, Johannes Geier, and Holger Lessmann. "Isopropyl myristate recommended for aimed rather than routine patch testing." Contact Dermatitis 50, no. 4 (2004): 242–44. http://dx.doi.org/10.1111/j.0105-1873.2004.00352.x.

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19

Tong, Philip L., and Elizabeth T. Chow. "Isopropyl myristate contact allergy: could your moisturizer be the culprit?" Contact Dermatitis 77, no. 3 (2017): 184–85. http://dx.doi.org/10.1111/cod.12799.

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20

Klaffenbach, P., and D. Kronenfeld. "Analysis of impurities of isopropyl myristate by gas-liquid chromatography." Journal of Chromatography A 767, no. 1-2 (1997): 330–34. http://dx.doi.org/10.1016/s0021-9673(96)01069-2.

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21

Wolf, B. "Hydrophilic-Lipophilic Drug Carrier Systems of Bead Cellulose and Isopropyl Myristate." Drug Development and Industrial Pharmacy 24, no. 11 (1998): 1007–15. http://dx.doi.org/10.3109/03639049809089944.

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22

Tuntiyasawasdikul, Sarunya, Ekapol Limpongsa, Napaphak Jaipakdee, and Bungorn Sripanidkulchai. "Transdermal Permeation of Kaempferia parviflora Methoxyflavones from Isopropyl Myristate-Based Vehicles." AAPS PharmSciTech 15, no. 4 (2014): 947–55. http://dx.doi.org/10.1208/s12249-014-0122-y.

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23

Zhou, Lihua, Yu Niu, Jinbei Yang, et al. "Reaction kinetics for synthesis of isopropyl myristate catalyzed by sulfated titania." Korean Journal of Chemical Engineering 33, no. 8 (2016): 2478–85. http://dx.doi.org/10.1007/s11814-016-0094-6.

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24

Hadgraft, Jonathan, and Geoffrey Ridout. "Development of model membranes for percutaneous absorption measurements. I. Isopropyl myristate." International Journal of Pharmaceutics 39, no. 1-2 (1987): 149–56. http://dx.doi.org/10.1016/0378-5173(87)90210-9.

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25

Harms, Meike, Stefan Mackeben, and Christel C. Müller-Goymann. "Thermotropic transition structures in the ternary system lecithin/isopropyl myristate/water." Colloids and Surfaces A: Physicochemical and Engineering Aspects 259, no. 1-3 (2005): 81–87. http://dx.doi.org/10.1016/j.colsurfa.2005.02.013.

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26

Verma, M., G. Chauhan, and S. Kanwar. "Enzymatic synthesis of isopropyl myristate using immobilized lipase fromBacillus cereusMTCC 8372." Acta Microbiologica et Immunologica Hungarica 55, no. 3 (2008): 327–42. http://dx.doi.org/10.1556/amicr.55.2008.3.4.

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27

Bardhan, Soumik, Kaushik Kundu, Swapan K. Saha, and Bidyut K. Paul. "Physicochemical studies of mixed surfactant microemulsions with isopropyl myristate as oil." Journal of Colloid and Interface Science 402 (July 2013): 180–89. http://dx.doi.org/10.1016/j.jcis.2013.04.008.

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28

SAUTINA, N. V., A. T. GUBAIDULLIN, and YU G. GALYAMETDINOV. "PECULIARITIES OF STRUCTURAL PHASE TRANSITIONS IN A SELF-ORGANIZING AOT/WATER/ISOPROPYL MYRISTATE SYSTEM UPON INTRODUCTION OF L-LYSINE." Коллоидный журнал 85, no. 2 (2023): 233–43. http://dx.doi.org/10.31857/s0023291223600013.

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New biocompatible microemulsion and liquid-crystalline sodium bis(2-ethylhexyl) sulfosuccinate (AOT)/water/isopropyl myristate systems have been obtained for the delivery of drugs and physiologically active substances. A combination of dynamic light scattering and X-ray diffraction methods has been used to determine their structural and size characteristics. The Primus and SasView software packages have been employed to simulate the shape and arrangement of particles as depending on AOT content. It has been shown that, as the concentration of the surfactant increases, the shape of micelles var

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29

Dalibera, Natália Cristina, Maria Helena Ambrosio Zanin, Kleber Lanigra Guimaraes, Leonardo Alencar de Oliveira, and Adriano Marim de Oliveira. "Optimized formulation of thermoresponsive nanoemulsion-based gel for enhanced oil recovery (EOR) application." Applied Petrochemical Research 11, no. 2 (2021): 155–63. http://dx.doi.org/10.1007/s13203-021-00269-9.

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AbstractA thermoresponsive system of a nanoemulsion-based gel with favorable characteristics to enhanced oil recovery (EOR) application is presented. A full factorial design study with different formulations of thermosensitive nanoemulsion-based gels was performed to assess the influence of the oil chain length, concentration of polyethylene glycol (PEG 400) and concentration of oil on the rheological behavior of the system. A formulation with low viscosity at room temperature and high viscosity at the temperature of the oil extraction well was presented. Hexane (6-carbon chain), capric acid (

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30

Bagci, Nuray, Zerrin Sezgin Bayindir, Ozge Inal, Nurten Altanlar, and Nilufer Yuksel. "Development and In vitro Evaluation of Nifedipine Gel Formulations for Anorectal Applications." Current Drug Delivery 17, no. 2 (2020): 126–39. http://dx.doi.org/10.2174/1567201817666200102125242.

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Objective: Current study focuses on the formulation and characterization of lipophilic and hydrophilic gel formulations of nifedipine to treat anal fissure via anodermal application. Methods: Lipophilic gels were prepared with Aerosil grades as gelling agents in bulk oils. Polyethylene glycols, hydroxypropyl methylcellulose, and Carbopol® 974P were used as gelling agents in water and propylene glycol for forming hydrophilic gels. The effect of repeated Freeze-Thaw Cycles (FT-C) on microstructures of the gels was investigated by examining viscosity, rheology and textural properties. Aerosil 200

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31

Gieszinger, Péter, Tamás Kiss, Piroska Szabó-Révész, and Rita Ambrus. "The Development of an In Vitro Horizontal Diffusion Cell to Monitor Nasal Powder Penetration Inline." Pharmaceutics 13, no. 6 (2021): 809. http://dx.doi.org/10.3390/pharmaceutics13060809.

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The development of in vitro investigation models could be important using sensitive and fast methods during formulation. Intranasal applied drugs (meloxicam, lamotrigine, and levodopa) avoid the gastrointestinal tract and can achieve higher bioavailability, therefore a penetration extent is a key property. In this study, the in vitro adaptability of a modified horizontal diffusion cell was tested by using these model active pharmaceutical ingredients (APIs). The special factors consisted of the volume of the chambers, the arrangement of the stirrers, the design of probe input for real-time ana

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32

Mohamed, M., F. Ghazy, M. Mahdy, and M. Gad. "RELEASE CHARACTERISTICS OF CAFFEINE AND MEBEVERINE HYDROCHLORIDE FROM ISOPROPYL MYRISTATE MULTIPLE EMULSIONS." Bulletin of Pharmaceutical Sciences. Assiut 13, no. 2 (1990): 247–54. http://dx.doi.org/10.21608/bfsa.1990.70582.

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33

Zidan, Ahmed S., Nahid Kamal, Alaadin Alayoubi, et al. "Effect of Isopropyl Myristate on Transdermal Permeation of Testosterone From Carbopol Gel." Journal of Pharmaceutical Sciences 106, no. 7 (2017): 1805–13. http://dx.doi.org/10.1016/j.xphs.2017.03.016.

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34

Armstrong, N. Anthony, Hazel-Anne Griffiths, and Kenneth C. James. "Migration of ephedrine and salicylic acid from lipid mixtures containing isopropyl myristate." International Journal of Pharmaceutics 41, no. 3 (1988): 205–11. http://dx.doi.org/10.1016/0378-5173(88)90193-7.

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35

Henderson, Gregg, David C. Blouin, and Robert L. Jeanne. "Yellowjacket (Hymenoptera: Vespidae) Repellency by Natural Products of Paper Wasps and Avon's Skin-so-Soft©." Journal of Entomological Science 28, no. 4 (1993): 387–92. http://dx.doi.org/10.18474/0749-8004-28.4.387.

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Methyl palmitate and butyl palmitate, ant repellents first isolated from the sternal glands of paper wasps, were tested with a methyl ester homolog, methyl myristate, and Avon's Skin-So-Soft Bath Oil© against foraging German yellowjackets. Repellency remained high for six days for all compounds except methyl palmitate. Avon's Skin-So-Soft© was the most repellent. We suggest that this is due to two active ingredients, isopropyl palmitate and mineral oil.

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36

Brinkmann, I., and C. C. Müller-Goymann. "Role of Isopropyl Myristate, Isopropyl Alcohol and a Combination of Both in Hydrocortisone Permeation across the Human Stratum corneum." Skin Pharmacology and Physiology 16, no. 6 (2003): 393–404. http://dx.doi.org/10.1159/000072935.

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37

Ashara, Kalpesh C., and Ketan V. Shah. "Nuts and Bolts of Oil and Temperature in Topical Preparations of Salicylic Acid." Folia Medica 59, no. 3 (2017): 279–88. http://dx.doi.org/10.1515/folmed-2017-0034.

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AbstractBackground:Traditional formulations of salicylic acid in ointment bases have disadvantages of being greasy and irritant due to free crystals.Aim:To explore the method for selection of oils and their ratio for topical preparation on the basis of equilibrium solubility study of salicylic acid and to evaluate temperature effect.Materials and methods:Scanning and calibration curve of salicylic acid in methanol were developed. Among available oils, those that had no interference of absorbance of salicylic acid were short-listed for screening purpose. Selections of oils were carried out on t

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Atipairin, Apichart, Charisopon Chunhachaichana, Titpawan Nakpheng, Narumon Changsan, Teerapol Srichana, and Somchai Sawatdee. "Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism." Pharmaceutics 12, no. 11 (2020): 1055. http://dx.doi.org/10.3390/pharmaceutics12111055.

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Sildenafil citrate is used to treat mild to moderate erectile dysfunction and premature ejaculation. However, it has low oral bioavailability, numerous adverse effects, and delayed onset of action. These problems may be resolved by transdermal delivery to the penis. Hence, sildenafil citrate was formulated as a microemulsion system using isopropyl myristate, Tween 80, PEG400, and water (30:20:40:10). The hydrogel used in the microemulsion was 2% w/w poloxamer 188. The sildenafil microemulsion-loaded hydrogels were characterised for their appearance, particle size, pH, spreadability, swelling i

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39

Yeoh, Soo Chin, Poh Lee Loh, Vikneswaran Murugaiyah, and Choon Fu Goh. "Development and Characterisation of a Topical Methyl Salicylate Patch: Effect of Solvents on Adhesion and Skin Permeation." Pharmaceutics 14, no. 11 (2022): 2491. http://dx.doi.org/10.3390/pharmaceutics14112491.

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The advent of skin patch formulation design and technology has enabled the commercialisation of methyl salicylate (MS) as a topical patch. However, the most fundamental aspect of skin permeation is unknown at present. The study aims to investigate the effect of solvent choice on the skin permeation of MS in a neat solvent system and patch formulation with an emphasis on patch adhesion. MS in six selected solvents (propylene glycol (PG), Transcutol®, isopropyl myristate, Labrasol®, Plurol® oleique CC 497 and Maisine® CC) was characterised and in vitro permeation studies were also performed. An

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40

Imran Ullah, Dr. Rahman Gul, Syed Umer Jan, et al. "Design, Formulation Development and Characterization of Transdermal Patches Loaded with Pseudoephedrine and Loratadine." Physical Education, Health and Social Sciences 3, no. 2 (2025): 822–30. https://doi.org/10.63163/jpehss.v3i2.422.

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ABSTARCT Objective The purpose of this study was to develop the transdermal patch with a combination of pseudoephedrine HCL and Loratadine . Methodology Various formulations of these anti-anthetic drugs were prepared using Eudragit RL100 as primary polymer. Ethyl cellulose (EC), twin 80, isopropyl myristate (IPM), Propylene Glycol (PG), and Span 20 were included as those who enhance transit. The finished patch was evaluated to their visual properties, including clarity, smoothness and brittleness. Additionally, thickness, pharmaceutical content, Fourier transform infrared spectroscopy (FTIR),

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41

Zhao, Xue Yan, Yu Rong Cao, Rui Jie Xiao, and Gui Rong Cao. "Rheological Properties and Microstructures of Thermo-Sensitive Microemulsion-Based Gels." Advanced Materials Research 557-559 (July 2012): 1009–12. http://dx.doi.org/10.4028/www.scientific.net/amr.557-559.1009.

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Thermo-sensitive microemulsion-based gels (MBGs) were prepared by the addition of Pluronic P123 (PEO20PPO70PEO20) into O/W microemulsion composed of isopropyl myristate (IPM)/Span20/Tween20/H2O. The results of rheological measurements indicate that the viscoelastic properties of the systems increase and the gelation temperatures decrease with increasing P123 concentration. Fluorescence spectroscopy was used to study the micropolarity of the hydrogel (P123/H2O), microemulsion and MBGs systems. The results show that the microstructures of microemulsion droplets are maintained in MBGs.

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Roohpour, Nima, Jaroslaw Wasikiewicz, Alireza Moshaverinia, Deepen Paul, Ihtesham Rehman, and Pankaj Vadgama. "Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices." Materials 2, no. 3 (2009): 719–33. http://dx.doi.org/10.3390/ma2030719.

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von Corswant, Christian, and Olle Söderman. "Effect of Adding Isopropyl Myristate to Microemulsions Based on Soybean Phosphatidylcholine and Triglycerides." Langmuir 14, no. 13 (1998): 3506–11. http://dx.doi.org/10.1021/la971248d.

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You, Yi, Baoxiang Zhong, and Jianxi Zhao. "Adsorption and micellization of alkanediyl-bis(dimethyldodecylammonium bromide) in isopropyl myristate/aqueous system." Colloid and Polymer Science 288, no. 14-15 (2010): 1359–67. http://dx.doi.org/10.1007/s00396-010-2265-z.

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Wasikiewicz, Jaroslaw M., Deepen Paul, Nima Roohpour, Jaina Vaghela, Michael F. Grahn, and Pankaj Vadgama. "Isopropyl myristate modified silicone as a potential new encapsulating material for implantable devices." Journal of Applied Polymer Science 119, no. 5 (2010): 2917–24. http://dx.doi.org/10.1002/app.32972.

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Panda, Dibya Sundar, Hussein M. Eid, Mohammed H. Elkomy, et al. "Berberine Encapsulated Lecithin–Chitosan Nanoparticles as Innovative Wound Healing Agent in Type II Diabetes." Pharmaceutics 13, no. 8 (2021): 1197. http://dx.doi.org/10.3390/pharmaceutics13081197.

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The aim of this research is to formulate a lecithin–chitosan based nanoparticulate system loaded with berberine (BER-LC-CTS-NPs) that could be integrated into a topically applied formulation and assessed for healing wounds in a diabetic animal model. In order to formulate BER-LC-CTS-NPs, soybean lecithin, isopropyl myristate, and berberine dispersed in ethanolic solution were added into an aqueous solution of chitosan dropwise with sonication. We assessed the influence of lecithin amount, chitosan amount, and isopropyl myristate concentration on particle diameter, zeta potential, and entrapmen

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Birbilis, Dimitris, Kostantinos V. Kakavas, and M. Chavenetidou. "Pinus brutia extractives analysis for sustainability." E3S Web of Conferences 436 (2023): 08005. http://dx.doi.org/10.1051/e3sconf/202343608005.

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The aim of this study was to determine all the extractives from different samples were collected from heartwood, sapwood, bark and needles and branches of Pinus brutia. A Soxlet device with two solvents (water and ethanol) were used to collect the extracts. Analytical chemical analyses were conducted with Gas C1hromatography-Mass Spectrometry (Agilent 5975C). The greater percentage of the extracts in water and ethanol showed that the greater percentage of them is found in the branches and needles of the trees. Especially the results showed significant amounts of the chemical compounds, such as

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Mitriaikina, S., and C. C. Muller-Goymann. "Synergetic effects of isopropyl alcohol (IPA) and isopropyl myristate (IPM) on the permeation of betamethasone-17-valerate from semisolid Pharmacopoeia bases." Journal of Drug Delivery Science and Technology 17, no. 5 (2007): 1–8. http://dx.doi.org/10.1016/s1773-2247(07)50052-3.

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Varshosaz, J., S. Andalib, M. Tabbakhian, and N. Ebrahimzadeh. "Development of Lecithin Nanoemulsion Based Organogels for Permeation Enhancement of Metoprolol through Rat Skin." Journal of Nanomaterials 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/139437.

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Background. Drugs with low oral bioavailability due to the first pass metabolism are good candidates for transdermal delivery.Objectives.The aim of this work was preparation of transdermal nanoemulsion of metoprolol which has high first pass metabolism.Methods. Three commercially available types of lecithin (200, 100p, and 170), three short chain alcohol (n-butanol, isopropyl alcohol, and n-propanol), and isopropyl myristate (IPM) were used as surfactant, cosurfactant, and oil phase, respectively. The aqueous phase was composed of metoprolol tartrate. Nanoemulsions with different surfactant/co

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Furuishi, Takayuki, Toshiro Fukami, Toyofumi Suzuki, Kozo Takayama, and Kazuo Tomono. "Synergistic Effect of Isopropyl Myristate and Glyceryl Monocaprylate on the Skin Permeation of Pentazocine." Biological & Pharmaceutical Bulletin 33, no. 2 (2010): 294–300. http://dx.doi.org/10.1248/bpb.33.294.

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