Relevant bibliographies by topics / Isoquinoline. Alkaloids

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Isoquinoline. Alkaloids'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Isoquinoline. Alkaloids"

1

Solongo, A., R. Istatkova, S. Philipov, S. Javzan, and D. Selenge. "Phytochemical study on Berberis sibirica Pall." Mongolian Journal of Chemistry 12 (September 24, 2014): 117–22. http://dx.doi.org/10.5564/mjc.v12i0.185.

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From the aerial parts (700g) of berberis sibirica pall. 6 isoquinoline alkaloids of protoberberine, protopine, benzophenantridine and proaporphine type were isolated. The known alkaloids (-)-tetrahydropseudocoptisine, pseudoprotopine, (+)-chelidonine and (+)-glaziovine are new for the family berberidaceae. from the aerial part ii (3.9 kg) 14 isoquinoline alkaloids of aporphine, proaporphine, protoberberine, protopine, benzylisoquinoline, bisbenzylisoquinoline,proaporphine-benzylisoquinoline and simple isoquinolin type were isolated and identified. The aporphine alkaloid 1-o-methylisotebaidine
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Min, Xinyi, Ting Zhu, Xinyi Hu, Cong Hou, Jianing He, and Xia Liu. "Transcriptome and Metabolome Analysis of Isoquinoline Alkaloid Biosynthesis of Coptis chinensis in Different Years." Genes 14, no. 12 (2023): 2232. http://dx.doi.org/10.3390/genes14122232.

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Coptis chinensis is a perennial herb of the Ranunculaceae family. The isoquinoline alkaloid is the main active component of C. chinensis, mainly exists in its rhizomes and has high clinical application potential. The in vitro synthesis of isoquinoline alkaloids is difficult because their structures are complex; hence, plants are still the main source of them. In this study, two-year and four-year rhizomes of C. chinensis were selected to investigate the effect of growth years on the accumulation of isoquinoline alkaloids. Two-year and four-year C. chinensis were selected for metabolomics detec
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Mandrekar, Ketan S., and Santosh G. Tilve. "P4O10/TfOH mediated domino condensation–cyclization of amines with diacids: a route to indolizidine alkaloids under catalyst- and solvent-free conditions." RSC Advances 12, no. 28 (2022): 17701–5. http://dx.doi.org/10.1039/d2ra02534e.

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A highly efficient and direct methodology for the construction of pyrrolo[2,1-a]isoquinoline, pyrido[2,1-a]isoquinoline, and 12b-H and 12b-OH isoindolo[2,1-a]isoquinolinone alkaloids from commercially available synthons is devised.
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Doncheva, Tsvetelina, Gabriela Yordanova, Vassil Vutov, Nadezhda Kostova, and Stefan Philipov. "Comparative Study of Alkaloid Pattern of Four Bulgarian Fumaria Species." Natural Product Communications 11, no. 2 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100220.

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The alkaloid pattern of four Fumaria species ( Fumaria kralikii, Fumaria rostellata, Fumaria schleicherii, Fumaria thuretii) growing in Bulgaria was investigated by GC-MS and twenty isoquinoline alkaloids were determined. Phytochemical investigation of the alkaloid composition on Fumaria thuretii Boiss was made for the first time. The alkaloid profile of the species was compared at two levels, between different species and within two species from different habitats. Two chemotypical groups, based on the types of isoquinoline alkaloids were suggested. To group A belong species F. kralikii, F. r
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Zhang, Yangyang, Yun Kang, Hui Xie, Yaqin Wang, Yaoting Li, and Jianming Huang. "Comparative Transcriptome Analysis Reveals Candidate Genes Involved in Isoquinoline Alkaloid Biosynthesis in Stephania tetrandra." Planta Medica 86, no. 17 (2020): 1258–68. http://dx.doi.org/10.1055/a-1209-3407.

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AbstractThe roots of Stephania tetrandra are used as a traditional Chinese medicine. Isoquinoline alkaloids are considered to be the most important and effective components in this herb, but little is known about the molecular mechanism underlying their biosynthesis. In this context, this study aimed to reveal candidate genes related to isoquinoline alkaloid biosynthesis in S. tetrandra. Determination of tetrandrine and fangchinoline in the roots and leaves of S. tetrandra by HPLC showed that the roots had much higher contents of the two isoquinoline alkaloids than the leaves. Thus, a comparat
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Kmieciak, Anna, Marta Ćwiklińska, Karolina Jeżak, Afef Shili, and Marek P. Krzemiński. "Searching for New Biologically Active Compounds Derived from Isoquinoline Alkaloids." Chemistry Proceedings 3, no. 1 (2020): 97. http://dx.doi.org/10.3390/ecsoc-24-08417.

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Many isoquinoline alkaloids are biologically active compounds and successfully used as pharmaceuticals. Compounds belonging to the isoquinolines and tetrahydroisoquinolines (TIQs) can be used as anesthetics, antihypertensive drugs, antiviral agents, and vasodilators. In the presented studies, the search for new compounds and synthesis of tetrahydroisoquinoline alkaloid derivatives was undertaken. Several dihydroisoquinolines were synthesized by Bishler–Napieralski reaction from the corresponding amides. Dihydroisoquinolines were reduced with sodium borohydride to obtain racemic tetrahydroisoqu
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Parvin, Mst, Marcel Hrubša, Jaka Fadraersada, et al. "Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?" Toxins 14, no. 7 (2022): 491. http://dx.doi.org/10.3390/toxins14070491.

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Isoquinoline alkaloids have multiple biological activities, which might be associated with positive pharmacological effects as well as negative adverse reactions. As bleeding was suggested to be a side effect of the isoquinoline alkaloid berberine, we decided to ascertain if different isoquinoline alkaloids could influence hemocoagulation through the inhibition of either platelet aggregation or blood coagulation. Initially, a total of 14 compounds were screened for antiplatelet activity in whole human blood by impedance aggregometry. Eight of them demonstrated an antiplatelet effect against ar
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Shklyaev, Yu V. "Isoquinoline alkaloids Amarillidaceae. Crinal alkaloids." All the Materials. Encyclopedic Reference Book., no. 13 (2022): 3–18. http://dx.doi.org/10.31044/1994-6260-2022-0-13-3-18.

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Qing, Zhi-Xing, Jia-Lu Huang, Xue-Yi Yang, et al. "Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and their Structure-activity Relationship." Current Medicinal Chemistry 25, no. 38 (2019): 5088–114. http://dx.doi.org/10.2174/0929867324666170920125135.

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The severe anticancer situation as well as the emergence of multidrug-resistant (MDR) cancer cells has created an urgent need for the development of novel anticancer drugs with different mechanisms of action. A large number of natural alkaloids, such as paclitaxel, vinblastine and camptothecin have already been successfully developed into chemotherapy agents. Following the success of these natural products, in this review, twenty-six types of isoquinoline alkaloids (a total of 379 alkaloids), including benzyltetrahydroisoquinoline, aporphine, oxoaporphine, isooxoaporphine, dimeric aporphine, b
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Bringmann, Gerhard, Markus Rückert, Jan Schlauer, and Markus Herderich. "Acetogenic isoquinoline alkaloids." Journal of Chromatography A 810, no. 1-2 (1998): 231–36. http://dx.doi.org/10.1016/s0021-9673(98)00257-x.

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Dissertations / Theses on the topic "Isoquinoline. Alkaloids"

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Streetley, Guy Bradwell. "New approaches for the asymmetric synthesis of pyrroloisoquinoline and isoquinoline alkaloids." Thesis, Loughborough University, 2006. https://dspace.lboro.ac.uk/2134/34917.

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Pyrroloisoquinoline (n = 1) and the pyridoisoquinoline (n = 2) ring systems (2) are found to be the major structural motif of the Erythrina and the protoberberine group of alkaloids, respectively. We have recognised that suitable bicyclic lactams (1) could act as precursors, in an intramolecular N-acyliminium ion-mediated cyclisation, resulting in a stereoselective approach to the core of the Erythrina and protoberberine ring systems. [Illustration omitted.] Access to the tetracyclic core of the Erythrina alkaloids (3) through the application of N-acyliminium ion chemistry is well established
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Si, Chong. "Synthesis of Cortistatin Alkaloids and a Versatile Synthesis of Isoquinolines." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10444.

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The cortistatins are a recently identified class of marine natural products that were found to exhibit potent and selective inhibition of human umbilical vein endothelial cells (HUVECs), making them promising leads for the development of anti-angiogenic drugs. In our synthesis, we envisioned that natural cortistatins and unnatural analogs could be prepared by late-stage introduction of isoquinolines to 17-keto precursors, and that these differentially substituted precursors could all be derived from a common key intermediate 112. We developed a robust synthetic route to prepare gram quantities
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Carvalho, Kaline Rodrigues. "Bioactive alkaloids and phenolic Hippeastrum solandriflorum (Lindl.) - Amaryllidaceae." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13544.

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This work describes the phytochemical study of Hippeastrum solandriflorum(Amaryllidaceae)aiming the isolation and structural elucidation of new bioactive compounds, as well as its pharmacological investigation. The chemical investigation realized with the EtOH extract from bulbs, through chromatographic methods, including HPLC (reverse phase), resulting inthe isolation of ten compounds: a furan derivative: 5-(hydroxymethyl)furan-2-carbaldehyde(HS-1), two phenolic derivatives: piscidic acid (HS-2), eucomic acid (HS-3), and seven isoquinoline alkaloids: narciclasin ( HS-4), 2α-hydroxypseudo
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Tims, Michael C. "The chemical ecology of Hydrastis canadensis L. (Ranunculaceae) effects of root isoquinoline alkaloids on the Hydrastis endophyte, Fusarium oxysporum /." College Park, Md. : University of Maryland, 2006. http://hdl.handle.net/1903/4052.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2006.<br>Thesis research directed by: Cell Biology & Molecular Genetics. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Brine, Natalie Dawn. "Investigation of the phytochemistry and biological activity of isoquinoline alkaloids isolated from the South African medicinal plants, cyrtanthus sanguineus (Lindl.) walp. and cyrtanthus obliquus (L.f.)ait." Doctoral thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/3274.

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Bibliography: p. 128-140.<br>The term "traditional medicine" refers to the ways of protecting and restoring health that existed before the arrival of modern medicine. These approaches to health belong to the traditions of each country and have been handed down from generatio to generation.
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Bender, Christoph. "Stereoselektive Synthese neuartiger 1,2-Dihydroisochinoline als Vorstufen für die Alkaloidsynthese." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2008. http://dx.doi.org/10.18452/15728.

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Ausgangspunkte der vorliegenden Arbeit waren stereoselektive Synthesen von Reissert-Verbindungen über chirale N-Acylisochinoliniumsalze. Es galt die Konfiguration der erhaltenen Produkte zu beweisen und deren Synthesepotential zu erforschen. Ein Ziel dieser Arbeit war es, weiterführende Reaktionen für die Synthese von alkaloidanalogen Substanzen zu entwickeln. Es gelang, die Reissert-Reaktion mit Chlorameisensäurementhylester erfolgreich auf andere Heterocyclen als Isochinolin auszudehnen. Die Annahme eine stereoselektiven Verlaufes mußte korrigiert werden. Das Reissert-Produkt konnte mit eine
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Rinaldi, Maria Valeria Nani. "Avaliação da atividade antibacteriana e citotóxica dos alcalóides isoquinolínicos de Annona hypoglauca Mart." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-28032008-134727/.

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Annona hypoglauca Mart. foi coletada em área inundada da Floresta Amazônica, próximo à Manaus (Brasil). Os alcalóides foram obtidos do extrato bruto do caule por partição ácido-base, e a partir do resíduo dessa extração foi realizada a partição com solventes de diferentes polaridades, originando as frações livres de alcalóides. A partir da análise de CG-EM dos alcalóides totais foi possível caracterizar sete alcalóides aporfínicos (actinodafinina, anonaina, glaucina, isoboldina, isodomesticina, nornuciferina e roemerina) e possivelmente duas protoberberinas (esculerina e caseadina). Os alcalói
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Siqueira, Carlos Alberto Theodoro. "Aspectos químicos e atividade antiprotozoária in vitro de Annona coriacea Mart. (Annonaceae)." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-31012011-140840/.

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Estudos anteriores dos alcalóides totais (AT) de Annona coriacea Mart. (Annonaceae) revelaram atividade antiprotozoária promissora. No presente trabalho, realizou-se o fracionamento biomonitorado dos AT de folha e selecionaram-se duas frações ativas (100% morte), frente às formas promastigotas de Leishmania (L.) chagasi in vitro, para a caracterização dos alcalóides, por CG-EM. Os AT bioativos de caule (100% morte) foram analisados sem fracionamento prévio. Em paralelo, efetuou-se amostragem de três exemplares de A. coriacea, analisados em conjunto, para o acompanhamento da variação do rendime
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Santos, Maria de Fátima Costa. "Estudo fitoquímico e investigação da atividade citotóxica das folhas e cascas do caule de Guatteria pogonopus (Annonaceae)." Universidade Federal de Sergipe, 2015. https://ri.ufs.br/handle/riufs/6090.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This paper presents the results obtained of the phytochemical bioguide of methanol extracts of the leaves and stem bark of Guatteria pogonopus Mart., a species belonging to the family Annonaceae. The botanical material (leaves and stem bark) were collected in the National Park Serra de Itabaiana (PARNA), Sergipe, Brazil. The extracts were obtained by maceration method at room temperature initially with hexane and then methanol, resulting in the hexane (EHF e EHC) and methanol (EMF e EMC) extracts, respectively. The methanol extr
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Chow, Yit Lai. "Caenorhabditis elegans as a whole organism screening system for isoquinoline alkaloid bioactivities." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188834.

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Books on the topic "Isoquinoline. Alkaloids"

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Bentley, K. W. The Isoquinoline alkaloids. Harwood Academic Pub., 1998.

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D, Phillipson J., Roberts M. F, Zenk M. H. 1933-, and Phytochemical Society of Europe, eds. The Chemistry and biology of isoquinoline alkaloids. Springer-Verlag, 1985.

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Phillipson, J. David, Margaret F. Roberts, and M. H. Zenk, eds. The Chemistry and Biology of Isoquinoline Alkaloids. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70128-3.

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Rahman, A. U. Isoquinoline Alkaloids. Elsevier Science, 1994.

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Chemistry and Biology of Isoquinoline Alkaloids. Island Press, 1985.

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Shamma, Maurice. Isoquinoline Alkaloids Research 1972-1977. Springer London, Limited, 2012.

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Shamma, Maurice. Isoquinoline Alkaloids Chemistry and Pharmacology. Elsevier Science & Technology Books, 2012.

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Shamma, Maurice. Isoquinoline Alkaloids Research 1972-1977. Springer, 2012.

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Zenk, M. H., M. F. Roberts, and J. D. Phillipson. Chemistry and Biology of Isoquinoline Alkaloids. Springer, 2012.

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Robinson, Robert, and K. W. Bentley. Isoquinoline Alkaloids: A Course in Organic Chemistry. Elsevier Science & Technology Books, 2014.

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Book chapters on the topic "Isoquinoline. Alkaloids"

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dos Santos, Anderson R., and Nelissa P. Vaz. "Isoquinoline Alkaloids and Chemotaxonomy." In Sustainable Development and Biodiversity. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-30746-2_8.

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Seigler, David S. "Isoquinoline and Benzylisoquinoline Alkaloids." In Plant Secondary Metabolism. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_32.

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Herbert, R. B. "The Biosynthesis of Isoquinoline Alkaloids." In Proceedings in Life Sciences. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70128-3_14.

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Kametani, Tetsuji. "The Total Syntheses of Isoquinoline Alkaloids." In Total Synthesis of Natural Products. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470129661.ch1.

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Bisset, N. G. "Plants as a Source of Isoquinoline Alkaloids." In Proceedings in Life Sciences. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70128-3_1.

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Brown, R. T. "Biomimetic and Total Synthesis of Monoterpenoid Isoquinoline Alkaloids." In Proceedings in Life Sciences. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70128-3_13.

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Zenk, M. H., M. Rüffer, T. M. Kutchan, and E. Galneder. "Biotechnological Approaches to the Production of Isoquinoline Alkaloids." In Novartis Foundation Symposia. John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470513651.ch15.

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Whiteley, Chris G. "Nicotinic Acetylcholine Receptor Agonist Activity of Isoquinoline Alkaloids." In Neurotoxic Factors in Parkinson’s Disease and Related Disorders. Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-1269-1_48.

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Rueffer, M. "The Production of Isoquinoline Alkaloids by Plant Cell Cultures." In Proceedings in Life Sciences. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70128-3_18.

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Chow, Yit-Lai, and Fumihiko Sato. "Metabolic Engineering and Synthetic Biology for the Production of Isoquinoline Alkaloids." In Biotechnology for Medicinal Plants. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29974-2_14.

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Conference papers on the topic "Isoquinoline. Alkaloids"

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Hung, J., J. Castillo, I. Laboren, M. Rodríguez, and M. Hassegawa. "Measurement of antiphotooxidative properties of isoquinoline alkaloids using transient thermal lens spectroscopy." In Optics East 2005, edited by Mostafa Analoui and David A. Dunn. SPIE, 2005. http://dx.doi.org/10.1117/12.630074.

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Cahlíková, L., A. Al Mamun, O. Janďourek, et al. "Short Lecture “Isoquinoline alkaloids and their derivatives as a new class of antimycobacterial drugs”." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1758970.

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Vasilopoulos, S., I. Giannenas, K. Bitchava, et al. "Effect of isoquinoline alkaloids on trout performance antioxidant status and filet fatty acid profile." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759319.

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Zielińska, S., K. Suśniak, M. Krysa, et al. "Bio-elicitation stimulated isoquinoline alkaloids production in Chelidonium majus cells cultured on bio-nano-cellulose." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759137.

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Matkowski, A., K. Szyrner, A. Sobiecka, et al. "In vitro cultures of antimicrobial and antibiofilm isoquinoline alkaloids containing ornamental plant Corydalis cheilanthifolia Hemsl." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759078.

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Nagalingam, Arumugam, Dimiter B. Avtanski, Joesph Tomaszewski, et al. "Abstract 1228: Indolo-pyrido-isoquinolin based alkaloid inhibits epithelial-mesenchymal transition and stemness via activation of p53-miR34a axis." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1228.

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