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Relevant bibliographies by topics / Isoxazolino

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Academic literature on the topic 'Isoxazolino'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Isoxazolino"

1

Balalaie, Saeed, Mohammad Shamakli, Ali Nikbakht, et al. "Direct access to isoxazolino and isoxazolo benzazepines from 2-((hydroxyimino)methyl)benzoic acid via a post-Ugi heteroannulation." Organic & Biomolecular Chemistry 15, no. 27 (2017): 5737–42. http://dx.doi.org/10.1039/c7ob01142c.

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A diversity-oriented access to isoxazolino and isoxazolo benzazepines is elaborated via a post-Ugi heteroannulation involving intramolecular 1,3-dipolar cycloaddition reaction of nitrile oxides with alkenes and alkynes.

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Bartolotta, Roberta, Concetta La Rosa, and Donatella Nava. "New Strategy of Synthesis of Peramivir Analogues as Potential Neuraminidase Inhibitors." Synthesis 52, no. 06 (2019): 933–41. http://dx.doi.org/10.1055/s-0039-1690039.

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Highly functionalised potential neuraminidase (NA) inhibitors, analogues of peramivir, were synthesised via a new and versatile method starting from a stereoselective 1,3-dipolar cycloaddition reaction between the nitrile oxide derived from 2-ethylbutanal and the commercially available and inexpensive cyclopentadiene and 1,3-cyclohexadiene, which afforded the isoxazolino-cyclopentene or cyclohexene intermediates, respectively. The subsequent reaction of the C=C bond in different conditions allowed the functionalisation of the five (or six) membered carbon nucleus. Further functionalised deriva

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3

Lukevics, E., P. Arsenyan, and M. Veveris. "Synthesis, Vasodilating, Antithrombotic and Cardioprotective Activity of Pyridyl Substituted 5-Silyl(Germyl)Isoxazolines-2." Metal-Based Drugs 5, no. 4 (1998): 251–57. http://dx.doi.org/10.1155/mbd.1998.251.

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The reactions of [2+3] cycloaddition of pyridylnitrile oxides to vinyl- and allylgermanes proceed regioselectively and afford 5-Ge-substituted isoxazolines-2. We have synthesized 9 new pyridyl substituted 5-Si(Ge)-isoxazolines-2 and investigated their biological activity. The vasodilating, anticoagulant and cardioprotective activities of 5-Si(Ge) substituted isoxazolines-2 have been studied in vitro and in vivo. Substitution of the silicon atom for the germanium one leads to the significant increase in vasodilating, antithrombotic and cardioprotective activity. The insertion of the methylene g

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4

Murphy, James J., James G. Hamilton, and R. Michael Paton. "Synthesis and ring opening metathesis polymerisation of isoxazolino- and isoxazolidino-norbornenes." Polymer 47, no. 10 (2006): 3292–97. http://dx.doi.org/10.1016/j.polymer.2006.03.027.

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BAR, N. C., A. ROY, R. PATRA, B. ACHARI, and S. B. MANDAL. "ChemInform Abstract: Solvent and Salt Dependent 1,3-Dipolar Cycloaddition: Synthesis of Isoxazolidino- and Isoxazolino-Carbocycles." ChemInform 28, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.199734147.

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6

Koroleva, E. V., and F. A. Lakhvich. "Synthesis of 13,15-isoxazolino-15-heteroaryl-prostanoids." Chemistry of Heterocyclic Compounds 30, no. 4 (1994): 458–59. http://dx.doi.org/10.1007/bf01169942.

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A., K. KHALAFALLAH, I. M. KORAIEM A., A. EL MAGHRABY M., and A. SHINDY H. "Synthesis and Studies on some Heterocyclic Nitrogen Compounds." Journal of Indian Chemical Society Vol. 66, June 1989 (1989): 398–400. https://doi.org/10.5281/zenodo.5995285.

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<em>Chemistry Department, Aswan Faculty of Science, Aswan, Egypt</em> <em>Manuscript received 21 July 1968, revised 10 March 1989, accepted 12 April 1989</em> <strong>C</strong>ondensation of 4,9 -dioxopiperldine[2,3-<em>g</em>]-1,2,3,4 6,7,8,9-octahydroquinolinoquinone (1) with aromatic aldehydes yielded the corresponding 3,3-bis-benzylidene derivatives (2a-f). Interaction of 2a—f with hydrazines, bydroxylamine, urea and thiourea afforded a new bis(pyrazolino-, 4a — <em>f, 5</em>a—f <em>; </em>isoxazolino- 6a — f ; pyrimidine and/or pyrimidine-thione, 7a— f,

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KOROLEVA, E. V., and F. A. LAKHVICH. "ChemInform Abstract: Synthesis of 13,15-Isoxazolino-15-heteroarylprostanoids (III)." ChemInform 26, no. 10 (2010): no. http://dx.doi.org/10.1002/chin.199510290.

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9

Moggio, Yuri, Laura Legnani, Bruna Bovio, Misal Giuseppe Memeo, and Paolo Quadrelli. "Synthesis of novel anthracene derivatives of isoxazolino-carbocyclic nucleoside analogues." Tetrahedron 68, no. 5 (2012): 1384–92. http://dx.doi.org/10.1016/j.tet.2011.12.047.

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D. Tupare, Shrikrishna, and Sanjay B. Sonawale. "Synthesis of Some Novel Isoxazoline from Sec 3-Amino Pyridazine Chalcones and Their Antimicrobial Studies." Mediterranean Journal of Basic and Applied Sciences 07, no. 01 (2023): 133–40. http://dx.doi.org/10.46382/mjbas.2023.7110.

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Different novel isoxazolines were synthesized by the cyclization of secondary amino derivatives with pyridazine as a substituted intermediate in the presence of hydroxylamine hydrochloride. Isoxazoline is an important class of nitrogen and oxygen-containing five-membered heterocyclic compounds having great medicinal importance. Many heterocyclic, pharmaceutically active compounds have been synthesized using it as an intermediate. Due to this activity, it is found useful in the treatment of anti-fungal, anti-bacterial, anti-cancer, anti-amoebic, and anti-inflammatory agents. The structures of t

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Dissertations / Theses on the topic "Isoxazolino"

1

Knight, Julian Gary. "Diphenylphosphinoylalkyk isoxazoles and isoxazolines." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306451.

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2

Lager, Markku. "Isoxazoline Synthese, Eigenschaften und N-O-Bindungsspaltungen /." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=974370304.

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3

Young, Anne A. "Nitrile oxide/isoxazoline approach to higher sugars." Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/11655.

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The application of nitrile oxide/isoxazoline chemistry towards the synthesis of higher sugars (monosaccharides containing seven or more contiguous carbon atoms) has been investigated. This convergent approach, involving the cycloaddition of sugar derived alkene and nitrile oxide fragments and subsequent manipulation of the resulting isoxazoline, has much of the product stereochemistry preselected. Three ω-unsaturated monosaccharides were chosen for study: the D-glucose-derived six carbon unit (<i>94</i>), its C-3 epimer (<i>102</i>) and a seven carbon alkene, (<i>97</i>), prepared from D-galac

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Boyd, Ewan Campbell. "Synthetic applications of nitrile oxide/isoxazoline chemistry." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/12525.

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Three alkenes, (<i>R/S</i>)-2-phenyl-4-vinyl-4,5-dihydro-oxazole (<i>11</i>), (4<i>R</i>)-3-<i>N-t</i>-butoxycarbonyl-2,2-dimethyl-4-vinyloxazolidine (<i>12</i>) and (2<i>R</i>)-2-(<i>N-t</i>-butoxycarbonyl)aminobut-3-en-1-ol (<i>13</i>), have been prepared from (<i>S</i>)-serine and used in cycloaddition reactions with some common nitrile oxides, to investigate the effect of an allylic nitrogen at an α-chiral centre on π-facial selectivity. Alkene (<i>11</i>) was prepared in racemic form after an unexpected racemisation during its synthesis. Cycloaddition reactions with three nitrile oxides (

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Penman, Kenneth J. "The nitrile oxide/isoxazoline route to carbon-linked disaccharides." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/11249.

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A route to carbon-linked disaccharides (two monosaccharide units linked by a carbon bridge rather than a glycosidic oxygen) employing nitrile oxide/isoxazoline chemistry has been investigated. This convergent approach is based on cycloaddition of sugar-derived alkene and nitrile oxide fragments, followed by ring cleavage and functional group manipulation of the resulting 2-isoxazoline. Careful selection of the nitrile oxide and alkene fragments defines much of the stereochemistry of the products. Two ω-unsaturated hexofuranoses were chosen for study: 3-<i>O</i>-benzyl-5,6-dideoxy-1,2-<i>O</i>-

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Tavares, Aline. "Isoxazolinas: uma classe de materiais avançados revisitada." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/32776.

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Este trabalho descreve a síntese e caracterização de séries inéditas de materiais líquidocristalinos contendo o N-heterociclo isoxazolina. Este anel foi obtido a partir da reação de cicloadição [3+2] 1,3-dipolar de óxidos de nitrila a diferentes dipolarófilos. As propriedades térmicas foram analisadas por MOLP, DSC e TGA, e as propriedades ópticas através de espectros de absorção. O presente trabalho apresenta três publicações, um artigo submetido e dois em fase final de redação, todos relacionados à Tese. Na primeira publicação (Eur. J. Org. Chem. 2009, 889-897) foi obtida uma coleção de isox

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March, Andrew Ronald. "Application of nitrile oxide/isoxazoline chemistry in C-glycoside synthesis." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/12565.

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A route to <i>C</i>-glycosides and <i>C</i>-disaccharides with functionalised linkages has been investigated. This convergent strategy involves cycloaddition of selected alkenes and sugar derived nitrile oxide moieties. The resultant 2-isoxazolines can be modified and subsequently ring opened to afford compounds with carbonyl or amino containing linkages. The alkenes selected for study were two w-unsaturated monosaccharide derivatives: 5,6-dideoxy-1,2-<i>O</i>-isopropylidene-a-D-<i>xylo</i>-hex-5-enofuranose and methyl 5,6-dideoxy-2,3-<i>O</i>-isopropylidene-a-D-<i>lyxo</i>-hex-5-enofuranoside

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Leandro, Gonçalves Bonfim Reis Silvio. "Síntese e avaliação preliminar da atividade antinoceptiva e toxicidade de novas isoxazolil-aril-hidrazonas." Universidade Federal de Pernambuco, 2008. https://repositorio.ufpe.br/handle/123456789/3215.

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Made available in DSpace on 2014-06-12T16:28:59Z (GMT). No. of bitstreams: 2 arquivo2102_1.pdf: 2203105 bytes, checksum: 355011545cb1b9f8b811ca232623d364 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2008<br>Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco<br>A Química Medicinal, através de estratégias específicas, vem para estudar as razões moleculares da ação dos fármacos, descrevendo a relação entre a estrutura química e a atividade farmacológica, com objetivo de planejar, sintetizar e produzir moléculas com potenc

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Correia, de Almeida Gleybson. "Síntese e avaliação preliminar da atividade antimicrobiana e antichagásica de novas isoxazolil-aril-semicarbazonas, e tiossemicarbazonas e isoxazolil-nitrofurfuril-hidrazonas." Universidade Federal de Pernambuco, 2010. https://repositorio.ufpe.br/handle/123456789/2969.

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Made available in DSpace on 2014-06-12T16:25:37Z (GMT). No. of bitstreams: 2 arquivo1125_1.pdf: 3490678 bytes, checksum: 347a62790e8d9bfb7abcdf2e63109656 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2010<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Na literatura, há um grande número de trabalhos que buscam obter derivados de semicarbazonas e tiossemicarbazonas, contendo heterociclos, com aplicações farmacológicas, como antimicrobiana, antichagásica, antifúngica, antineoplásica e anticonvulsivante. Pesquisas vêm obte

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Wierschem, Frank Georg. "Darstellung und Modifizierung von 2-Oxo-piperazin-basierenden Isoxazolinen und Isoxazolidinen in Lösung und an fester Phase." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971626812.

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Books on the topic "Isoxazolino"

1

Friebolin, Wolfgang. Thermische und photochemische Umwandlungen von [delta]⁴-Isoxazolinen: Cyclisierungsreaktionen konjugierter Azomethinylide. 2000.

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2

Assmann, Lutz. Inter- und intramolekulare Diels-Alder-Reaktionen mit Furo[3,4-d]isoxazolen. 1991.

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3

Hillgardt, Jan. Synthese von 4a-Methyl-3,4,4a,5,6,7,8,8a-octahydrochinolin und Syntheseversuche von 2-Methyl-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridin. 1990.

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4

Lopez-Calle, Eloisa. Cyclisierungsreaktionen [alpha],[beta];[gamma],[delta]-ungesättigter Nitrone: Synthese von 13 Azasteroiden ; zur Photochemie von 4-Isoxazolinen : ein Weg zu Azomethin-Yliden: mechanistische und präparative Aspekte. 1995.

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Book chapters on the topic "Isoxazolino"

1

Quilico, Adolfo. "Isoxazolines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186787.ch2.

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Quilico, Adolfo. "Isoxazolone." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186787.ch3.

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3

Weber, Tina, and Paul M. Selzer. "Isoxazolines: A Novel Chemotype Highly Effective on Ectoparasites." In Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527694082.ch4.

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Weber, Tina, and Paul M. Selzer. "Isoxazolines: A Novel Chemotype Highly Effective on Ectoparasites." In Ectoparasites. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527802883.ch12.

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Long, Alan. "Isoxazolines: Preeminent Ectoparasiticides of the Early Twenty-first Century." In Ectoparasites. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527802883.ch16.

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Sohár, Pál, István Kövesdi, Géza Stájer, and Gábor Bernáth. "Structure Determination of a Norbornane-Norbornene-Fused Pentacyclic Isoxazoline by NMR Spectroscopy." In 25th Congress Ampere on Magnetic Resonance and Related Phenomena. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-76072-3_312.

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Woods, Debra J., and Tom L. McTier. "Discovery, Development, and Commercialization of Sarolaner (Simparica® ), A Novel Oral Isoxazoline Ectoparasiticide for Dogs." In Ectoparasites. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527802883.ch15.

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Simoni, Daniele, Stefano Manfredini, Mojgan Aghazade Tabrizi, et al. "Synthesys of Isoxazole and Isoxazoline Derivatives of Retinoids: Effects on Growth and Differentiation of Tumor Cells." In Topics in Molecular Organization and Engineering. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3620-4_10.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex of 3-(2-hydroxy-1-naphthyl)-5-(4-phenyl)-2-isoxazoline." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_122.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex of 3-(2-hydroxy-1-naphthyl)-5-(4-chlorophenyl)-2-isoxazoline." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_123.

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Conference papers on the topic "Isoxazolino"

1

Marjanović, Đorđe, Dragana Medić, Tihomir Marić, and Saša Trailović. "Exploring potential antinematodal effects of some insecticides from isoxazoline group." In 36. Savetovanje dezinfekcija, dezinsekcija i deratizacija jedan svet - jedno zdravlje, Vrnjačka Banja, hotel "Vrnjačke Terme", 28-31.maj 2025.godine. Srpsko veterinarsko društvo, 2024. https://doi.org/10.5937/ddd25095m.

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Isoxazoline insecticides, such as fluralaner, afoxolaner, and sarolaner, are widely used for pest control in agriculture and veterinary medicine due to their effectiveness against arthropods like fleas, ticks, and mites. These compounds work by targeting GABA receptors and chloride ion channels in insects and arachnids. Recent studies, however, suggest that isoxazolines may also have potential in combating nematodes, which pose significant challenges in agriculture and human health. Nematodes, including parasitic and free-living species, can cause severe damage to crops and livestock. Isoxazol

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Jiang, Shiyao. "Mosquitocidal activity and mode of action of the isoxazoline fluralaner." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.112752.

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Thiemann, Thies, Shuntaro Mataka, Christian Burmester, Masataka Watanabe, and Masao Imai. "Oxidative degradation of a steroidal isoxazoline: 1-formyl-7-methoxy-2-methylphenanthrene from 3\'-methoxyestra-1\',3\',5\'(10\')-trieno(16\',17\':4,5)isoxazoline." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00172.

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Bharathi, R., and N. Santhi. "Synthesis, docking studies and antioxidant activity of some chalcone and isoxazoline derivatives." In EIGHTH INTERNATIONAL CONFERENCE NEW TRENDS IN THE APPLICATIONS OF DIFFERENTIAL EQUATIONS IN SCIENCES (NTADES2021). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0076819.

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Passo, Joel A., and A. A. Merlo. "Synthesis and Characterization of New Comb-shape Copolymers Based on 3,5-Isoxazolines." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0269-1.

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Soares, Ozildéia, Gabriela R. Hurtado, Luiz H. Viana, Sérgio de Albuquerque, and Adriano C. M. Baroni. "Synthesis of Isoxazolic analogues derivatives of Grandisin and Veraguensin neolignans with anti-leishmania and antitrypanosomal activities." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_20139410384.

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