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Journal articles on the topic 'It4i'

Author: Grafiati

Published: 28 June 2021

Last updated: 29 July 2025

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1

Svatoš, Michal, Jiří Chudoba, and Petr Vokáč. "Updates on usage of the Czech national HPC center." EPJ Web of Conferences 251 (2021): 02008. http://dx.doi.org/10.1051/epjconf/202125102008.

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The distributed computing of the ATLAS experiment at LHC has used computing resources of the Czech national HPC center IT4Innovations for several years. The submission system is based on ARC-CEs installed at the Czech Tier2 site (praguelcg2). Recent improvements of this system will be discussed here. First, there was a migration of the ARC-CE from version 5 to 6 which improves the reliability and scalability. A shared filesystem built on top of sshfs 3.7 no longer represents performance bottleneck. It provided an order of magnitude better transfer performance. New Singularity containers with f

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Idowu Asegame Aimola, Godson Ofobuike Eze, and Yakubu Kokori Eneneve Ibrahim. "The Impact of BMH-21 on Parasite Load, Biochemical Indices, ESAG6 and ITS-I Genes of Trypanosoma brucei brucei Infected Albino Rats." Sumerianz Journal of Biotechnology, no. 74 (September 21, 2024): 105–15. http://dx.doi.org/10.47752/sjb.74.105.115.

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This study investigated the in vivo anti-trypanosomal activity of BMH-21. Wistar albino rats were randomly divided into eight groups, each consisting of five rats: IT20, IT40, and IT60. These groups received treatments with 20, 40, and 60 mg/kg body weight (bw) of BMH-21, respectively, after being infected. Additional groups included IUT (Infected-untreated), UUT (Uninfected-untreated), UT60 (Uninfected but given 60 mg/kg bw of BMH-21), P60 (administered 60 mg/kg bw of BMH-21 once, infected after 72 hours, with treatment continuing daily until Day 4), and ITDA (Infected and treated with 3.5 mg

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Umemura, Takashi, and Yumi Wako. "Pathogenesis of Osteomalacia in Itai-itai Disease." Journal of Toxicologic Pathology 19, no. 2 (2006): 69–74. http://dx.doi.org/10.1293/tox.19.69.

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Gourtsoyiannis, Nickolas. "Yuji Itai." European Radiology 13, no. 5 (2003): 1195–96. http://dx.doi.org/10.1007/s00330-003-1872-1.

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5

Morikawa, Yuko, Hideaki Nakagawa, Masaji Tabata, et al. "Study of an Outbreak of Itai-itai Disease." Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 46, no. 6 (1992): 1057–62. http://dx.doi.org/10.1265/jjh.46.1057.

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6

AOSHIMA, Keiko. "Itai-Itai Disease: Cadmium-Induced Renal Tubular Osteomalacia." Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 67, no. 4 (2012): 455–63. http://dx.doi.org/10.1265/jjh.67.455.

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AOSHIMA, Keiko. "Recent Advances in Studies of Itai-itai Disease." Eisei kagaku 43, no. 6 (1997): 317–30. http://dx.doi.org/10.1248/jhs1956.43.317.

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Chung, Juyong, Doh Young Lee, Jong Seung Kim, and Young Ho Kim. "Effectiveness of Intratympanic Dexamethasone Injection for Tinnitus Treatment: A Systematic Review and Meta-Analysis." Clinical and Experimental Otorhinolaryngology 15, no. 1 (2022): 91–99. http://dx.doi.org/10.21053/ceo.2021.01459.

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Objectives. Intratympanic dexamethasone injection (ITDI) has been introduced as a treatment option for subjective tinnitus. However, the effects of ITDI on patients with tinnitus remain unclear. In the present systematic review and metaanalysis, we evaluated the effectiveness of ITDI for tinnitus treatment.Methods. We searched Medline, the Cochrane Central Register of Controlled Trials, and Embase. Four double-blind randomized controlled trials that tested the efficacy of ITDI compared with a placebo were deemed eligible for a quantitative meta-analysis, while four prospective studies and seve

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Kawano, Shunichi, Hideaki Nakagawa, Yoshiharu Okumura, and Kenichiro Tsujikawa. "A mortality study of patients with Itai-itai disease." Environmental Research 40, no. 1 (1986): 98–102. http://dx.doi.org/10.1016/s0013-9351(86)80085-8.

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10

Inaba, Takeya, Etsuko Kobayashi, Yasushi Suwazono, et al. "Estimation of cumulative cadmium intake causing Itai–itai disease." Toxicology Letters 159, no. 2 (2005): 192–201. http://dx.doi.org/10.1016/j.toxlet.2005.05.011.

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11

Kern, Boris. "Word formation chains of denominal multistage derivatives with initial formant -iti in Slovenian." Juznoslovenski filolog 80, no. 2 (2024): 127–39. https://doi.org/10.2298/jfi2402127k.

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The article presents and analyzes the suffix combinatorics exhibited by denominal multistage derivatives whose initial suffix is -iti. An examination of whether the semantic restriction of the corpus material (sensory perception) yields different word formation chains than the non-restricted one (material resulting from the KOBOS project, including BSSJ, SSKJ 2 and the Gigafida 2.0 corpus) revealed that the combinatorial picture is quite different. The KOBOS material shows that the combinatorics of the initial suffix -iti is among the most diversified, encompassing 36 different suffix chains.

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Bryan, R. Nick. "Yuji Itai, MD." Radiology 228, no. 3 (2003): 905. http://dx.doi.org/10.1148/radiol.2283032522.

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Chen, Xiao, Guoying Zhu, Taiyi Jin, et al. "Cadmium exposure induced itai-itai-like syndrome in male rats." Open Medicine 6, no. 4 (2011): 425–34. http://dx.doi.org/10.2478/s11536-011-0046-9.

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AbstractFourteen Sprague-Dawley male rats were randomly divided into 2 groups which were given CdCl2 at the doses of 0 and 1.5 mg /kg for 12 weeks. Before sacrifice, microCT scanning were performed on the proximal tibia and urine were collected for cadmium and N-acetyl-beta-D-glucosaminidase assay, then all of rats were sacrificed and blood was collected for biomarkers measurement; bone tissues were collected for bone mass, histology and biomechanical analysis. The cadmium in blood, urine, bone and kidney of rats treated with cadmium was significantly higher than those in the control group. Th

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Baba, Hayato, Koichi Tsuneyama, Tokimasa Kumada, Keiko Aoshima, and Johji Imura. "Histopathological analysis for osteomalacia and tubulopathy in itai-itai disease." Journal of Toxicological Sciences 39, no. 1 (2014): 91–96. http://dx.doi.org/10.2131/jts.39.91.

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15

Nogawa, Koji, and Teruhiko Kido. "Biological monitoring of cadmium exposure in itai-itai disease epidemiology." International Archives of Occupational and Environmental Health 65, S1 (1993): S43—S46. http://dx.doi.org/10.1007/bf00381306.

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16

Nakada, T., H. Furuta, H. Koike, T. Katayama, and H. Teranishi. "Impaired urine concentrating ability in Itai-itai (ouch-ouch) disease." International Urology and Nephrology 21, no. 2 (1989): 201–9. http://dx.doi.org/10.1007/bf02550809.

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Kasuya, M., H. Teranishi, K. Aoshima, et al. "Water Pollution by Cadmium and the Onset of Itai-itai Disease." Water Science and Technology 25, no. 11 (1992): 149–56. http://dx.doi.org/10.2166/wst.1992.0286.

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Cadmium (Cd) from a zinc mine polluted Jinzu River basin, Toyama prefecture and produced a disease with severe bone pain (Itai-itai disease), from the early part of the 20th century. Cd caused renal tubular dysfunction and osteomalacia accompanied by osteoporosis. The main symptoms of the disease were bone pain, pseud fracture (Looser's zone), fracture, and renal tubular dysfunction. The pollution of paddy-field soil by Cd still remains and our epidemio1ogica1 studies of the inhabitants living in the Cd-polluted areas show the presence of renal tubular dysfunction and decrease of bone mass; ch

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Kasuya, M. "Recent epidemiological studies on itai-itai disease as a chronic cadmium poisoning in Japan." Water Science and Technology 42, no. 7-8 (2000): 147–54. http://dx.doi.org/10.2166/wst.2000.0563.

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Itai-itai disease is a chronic cadmium poisoning with renal tubular dysfunction followed by osteomalacia. Renal tubular dysfunction among inhabitants of the cadmium-polluted Jinzu River basin was irreversible and progressive, despite the fact that cadmium exposure had decreased. The bone mass was decreased in the inhabitants living in cadmium-polluted areas with renal tubular dysfunction, correlating with the urinary β2-microglobulin level. The decreased bone mass was diagnosed as latent renal tubular osteomalacia. Low serum erythropoietin levels were detected among the patients with itai-itai

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Tomiyoshi, Marcelo Hannemann, Rodrigo Kopp Rezende, Luiz Patrial Netto, Patricia Maria Sens, Lisandra Megumi Arima dos Santos, and Adriana Kosma Pires de Oliveira. "AUDIOLOGICAL RESPONSE IN THE USE OF INTRATYMPANIC DEXAMETHASONE IN SUDDEN DEAFNESS AT HOSPITAL IPO." Journal of Contemporary Diseases and Advanced Medicine 2, no. 2 (2023): 16–23. http://dx.doi.org/10.14436/jcdam.2.2.016-023.oar.

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Sudden sensorineural hearing loss (SSNHL) is an otolaryngological urgency yet to be fully understood, which can be treated with intratympanic steroid injections (ITSI), a treatment that, yet does not have a strict protocol. The objective of this study was to assess de efficacy of ITSI in patients afflicted with SSNHL treated in Hospital IPO. For that, thirty-four patients who underwent ITSI had their charts and audiometric exams reviewed to assess treatment efficacy both in audiological and symptomatic improvement and certain factors that could influence a positive outcome. In a mostly female

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Nakano, Masatoshi, Keiko Aoshima, Terutaka Katoh, Hidetoyo Teranishi, and Minoru Kasuya. "Elevation of urinary trehalase activity in patients of itai-itai disease." Archives of Toxicology 60, no. 4 (1987): 300–303. http://dx.doi.org/10.1007/bf01234669.

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21

Yamashita, H., and M. Kitagawa. "Histomorphometric study of ribs with Looser zones in Itai-itai disease." Calcified Tissue International 58, no. 3 (1996): 170–76. http://dx.doi.org/10.1007/bf02526883.

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Yamashita, H., and M. Kitagawa. "Histomorphometric Study of Ribs with Looser Zones in Itai-Itai Disease." Calcified Tissue International 58, no. 3 (1996): 170–76. http://dx.doi.org/10.1007/s002239900029.

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23

Рушина, Наталия Алексеевна, and Галина Владимировна Мирская. "USING ALLELE-SPECIFIC MARKERS OF GENE FOR THE EARLY FORMS SELECTION OF BREAD WHEAT IN THE INITIAL SELECTION STAGES." Вестник Бурятской государственной сельскохозяйственной академии имени В. Р. Филиппова, no. 3(60) (September 20, 2020): 45–54. http://dx.doi.org/10.34655/bgsha.2020.60.3.007.

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Выявление образцов, несущих нечувствительный к фотопериоду аллель Ppd-D1а, необходимо для использования в селекции скороспелых сортов яровой пшеницы. Целью нашего исследования был подбор селекционного материала методом молекулярно-генетического скрининга по наличию аллелей гена фотопериодизма Ppd-D1 и на основе оценки величины и степени проявления гетерозиса в F Использование этих двух методов позволяют отобрать генетический материал для ускоренной селекции новых форм пшеницы, сочетающих высокую скорость развития и повышенную продуктивность. Приведены результаты оценки яровой мягкой пшеницы по

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Kaczmarek, Łukasz, and Łukasz Michalczyk. "Thulinius itoi comb. nov. a new systematic position for Isohypsibius itoi (Tsurusaki, 1980) (Tardigrada: Eutardigrada: Hypsibiidae)." Zootaxa 1373 (December 31, 2006): 65–68. https://doi.org/10.5281/zenodo.174953.

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Kaczmarek, Łukasz, Michalczyk, Łukasz (2006): Thulinius itoi comb. nov. a new systematic position for Isohypsibius itoi (Tsurusaki, 1980) (Tardigrada: Eutardigrada: Hypsibiidae). Zootaxa 1373: 65-68, DOI: 10.5281/zenodo.174953

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Сарсенбаева, У. "Implementing ICT in improving receptive skills of ESP learners." Ренессанс в парадигме новаций образования и технологий в XXI веке 1, no. 1 (2023): 422–27. http://dx.doi.org/10.47689/xxia-ttipr-vol1-iss1-pp422-427.

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Using technology in language teaching process is not new. Actually, technology has been in language teaching process for decades – anyone can argue for centuries, if we can consider the blackboard as a technology. Type recorders, language laboratories and video have been in use since the 1960s and 1970s, and are still used in classrooms around the world

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Dargemont, C., D. Dunon, J. Salamero, M. A. Deugnier, J. Davoust, and J. P. Thiery. "Overproduction and secretion of beta 2-microglobulin by a rat thymic epithelial cell line that expresses MHC class I heavy chain." Journal of Cell Science 98, no. 4 (1991): 559–65. http://dx.doi.org/10.1242/jcs.98.4.559.

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Major histocompatibility complex (MHC) class I antigens are constituted of dimers consisting of a peripheral light chain, beta 2-microglobulin (beta 2m) and a transmembrane heavy chain whose cell surface expression depends on its assembly with beta 2m. In contrast, soluble beta 2m can be secreted in the absence of heavy chain expression. The presence of beta 2m in medium conditioned by a rat thymic epithelial cell line, IT45-R1 (IT45) prompted us to investigate whether beta 2m could be secreted by cells that express MHC class I antigens. IT45 cells produce three to five times more beta 2m in t

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Prunzel, Jaqueline, Marcos Toebe, Alexandre Bernardino Lopes, and Virnei Silva Moreira. "MODELOS DE REGRESSÃO LINEAR MÚLTIPLA APLICADOS À AVALIAÇÃO DE TERRENOS URBANOS - CASO DO MUNICÍPIO DE ITAQUI-RS." Boletim de Ciências Geodésicas 22, no. 4 (2016): 651–64. http://dx.doi.org/10.1590/s1982-21702016000400037.

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Este trabalho teve como objetivo identificar variáveis explicativas para a modelagem e predição do valor real (ITBI) e venal de lotes urbanos no município de Itaqui-RS utilizando o Método Comparativo Direto de Dados do Mercado, desenvolvido por regressão linear múltipla. Em uma amostra de 67 lotes foram avaliadas variáveis quantitativas: área, testada, valor do m2, valor venal e valor do ITBI e variáveis qualitativas: topografia, situação e pavimentação, sendo que para cada variável foram determinados parâmetros estatísticos incluindo a distribuição de dados por assimetria, curtose, teste de n

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Tambo, Torben, and Jacob Filtenborg. "Digital services governance: IT4IT™ for management of technology." Journal of Manufacturing Technology Management 30, no. 8 (2019): 1230–49. http://dx.doi.org/10.1108/jmtm-01-2018-0028.

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Purpose The purpose of this paper is to present, analyse and demonstrate the impact and potentials of a pragmatically derived information technology (IT) governance framework, IT4IT™, for the discipline of management of technology (MoT) especially within the IT industry. Design/methodology/approach This paper is based on an extensive literature study working with the limitations of the relatively recent publication of IT4IT™ and the normative character of IT4IT™. A mixed-method case study is presented based on an IT service provider organisation. Both a qualitative method and a systems and des

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Fokkink, Wan, and Jun Pang. "Variations on Itai-Rodeh Leader Election for Anonymous Rings and their Analysis in PRISM." JUCS - Journal of Universal Computer Science 12, no. (8) (2006): 981–1006. https://doi.org/10.3217/jucs-012-08-0981.

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We present two probabilistic leader election algorithms for anonymous unidirectional rings with FIFO channels, based on an algorithm from Itai and Rodeh [Itai and Rodeh 1981]. In contrast to the Itai-Rodeh algorithm, our algorithms are finite-state. So they can be analyzed using explicit state space exploration; we used the probabilistic model checker PRISM to verify, for rings up to size four, that eventually a unique leader is elected with probability one. Furthermore, we give a manual correctness proof for each algorithm.

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Ødum, Lars, Torben E. Jessen та Claus Yding Andersen. "Glycosaminoglycan-bound and free inter-α-trypsin inhibitor components of follicular fluid". Zygote 9, № 4 (2001): 283–88. http://dx.doi.org/10.1017/s0967199401001319.

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The proteinase inhibitor inter-α trypsin inhibitor (ITI) is a blood-derived protein necessary for normal female fertility. Absence of ITI leads to ovulation of naked oocytes that cannot fertilise. ITI consists of two heavy chains (ITI-HC) and bikunin linked by a chrondroitin sulphate. By binding to hyaluronate, ITI-HC stabilises the extracellular matrix, but ITI-HC also binds to proteoglycans in follicular fluid. In vivo concentrations of ITI components in preovulatory follicular fluid, free as well as bound to hyaluronate or proteoglycan, are unknown. In order to quantify these components, 58

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Yasuda, Masanori, Atsuo Miwa, and Masanobu Kitagawa. "Morphometric Studies of Renal Lesions in Itai-itai Disease: Chronic Cadmium Nephropathy." Nephron 69, no. 1 (1995): 14–19. http://dx.doi.org/10.1159/000188354.

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Li, Zhengping, Man-Chiu Poon, and Runhui Wu. "Low-Dose Immune Tolerance Induction Therapy for Severe Hemophilia a Inhibitor Patients: Immunosuppressants Improve Outcomes but Are Generally Not Necessary for Inhibitor-Titer below 200 BU/Ml." Blood 142, Supplement 1 (2023): 3988. http://dx.doi.org/10.1182/blood-2023-184514.

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Background We previously showed that low-dose immune tolerance induction (ITI) incorporating immunosuppressants (IS) for severe hemophilia A patients with inhibitor titer ≥40 Bethesda Units (BU)/mL (LD-ITI-IS 40 regimen) had relatively high success rate with lower cost compared to those on high-dose ITI. Recent evidence suggested that patients with inhibitor titer &lt;200 BU/mL do not need high-dose ITI raising the question that IS may also not be necessary. Objectives To compare the efficacy of LD-ITI incorporating IS only for inhibitor titer ≥200 BU/mL (LD-ITI-IS 200 regimen) with that o

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Guo, Jin, Meng Chen, Xialing Sun, Zhanzhao Wang, and Jinli Xue. "Leveraging industrial-technological innovation to achieve sustainable development: A systems thinking perspective." PLOS ONE 15, no. 12 (2020): e0242981. http://dx.doi.org/10.1371/journal.pone.0242981.

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Industrial-technological innovation (ITI) has become an important requirement for the sustainable development of China. ITI development requires a comprehensive understanding of the dynamic complexity associated with ITI systems. Previous research into ITI systems is based primarily on static methods that isolate system components, and ignore feedback on adjustments made. Based on systems thinking, this paper develop six archetypes (“Limit to Growth,” “Success to the Successful,” “Tragedy of the Commons,” “Fixes that Fail,” “Accidental Adversaries,” and “Shifting the Burden”) and an ITI system

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Callaghan, Michael U., Indira Warrier, Madhvi Rajpurkar, and Jeanne Lusher. "Immune Tolerance Induction in 28 Children with Hemophilia Awith Inhibitors." Blood 108, no. 11 (2006): 1046. http://dx.doi.org/10.1182/blood.v108.11.1046.1046.

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Abstract Aim: To study the characteristics, treatment, and outcome of patients with hemophilia with inhibitors who have undergone immune tolerance induction (ITI) at the Children’s Hospital of Michigan over the past 14 years. Methods: In compliance with local IRB regulations, patient charts and laboratory databases were reviewed and salient data extracted. 28 boys underwent 29 attempts at immune tolerance induction. Results: Hemophilia A 26 boys with severe hemophilia A with inhibitors underwent 27 trials of ITI. In this cohort of 26 patients the average age at which patients developed an inhi

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Hsu, Chin Lin, Shyankay Jou, Ying Ji Chuang, and Ching Yuan Lin. "Hydrophobic Coating on Silicon Wafer by Use of Industrial Coating-Bar Process in Atmosphere Parameter." Advanced Materials Research 941-944 (June 2014): 1577–80. http://dx.doi.org/10.4028/www.scientific.net/amr.941-944.1577.

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Silicon wafer is chosen in this work for the study of hydrophobic coating with industrial coating bar, due to the wafer has the superior flatness. Various amounts of TS-720 hydrophobic nano-particles were mixed into ITRI hydrophobic agent (H.A.), and this liquid mixture was applied onto material surface by use of a coating bar. In this study, we added the TS-720 nanoparticle from 0 – 2.5 wt% with ITRI H.A. The contact angle is higher than 135o, when we have 2.5 wt% TS-720 nanoparticle adding in ITRI H.A.

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Predieri, Stefano, Fiorella Sinesio, Erminio Monteleone, et al. "Gender, Age, Geographical Area, Food Neophobia and Their Relationships with the Adherence to the Mediterranean Diet: New Insights from a Large Population Cross-Sectional Study." Nutrients 12, no. 6 (2020): 1778. http://dx.doi.org/10.3390/nu12061778.

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The Mediterranean diet (MD) is associated with many health benefits. The association between the MD and food neophobia (FN) is still unexplored in adults. The present cross-sectional study was aimed to explore the relationships between adherence to the MD, FN, and sociodemographic variables in a large Italian cohort. Familiarity and frequency use (FFI) of prototypical and non-prototypical Mediterranean foods were used to calculate a new adherence index: the Italian Taste Mediterranean Index (ITMI). The FFI of all Mediterranean foods increased with age, while butter, soft drinks, red/cured meat

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Nduru, Evi Kartini, and Lanta Siringo ringo. "PENGARUH PELAYANAN AKADEMIK TERHADAP TINGKAT KEPUASAN MAHASISWA PADA STMIK ITMI MEDAN." JURNAL GLOBAL MANAJEMEN 10, no. 1 (2021): 152. http://dx.doi.org/10.46930/global.v10i1.1785.

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Pelayanan akademik merupakan semua tindakan atau kegiatan yang dapat ditawarkan oleh satu pihak kepada pihak lain yang pada dasarnya tidak terwujud dan tidak menghasilkan kepemilikan apapun. Sedangkan Kepuasan Pelanggan adalah tingkat perasaan konsumen setelah membandingkan antara apa yang dia terima dan harapannya. Adapun rumusan masalah dalam penelitian ini adalah “Apakah Pelayanan Akademik Berpengaruh Terhadap Kepuasan Mahasiswa Pada STMIK ITMI Medan?” Kerangka berpikir dalam penelitian ini terdiri dari dua variabel yaitu : Variabel X (Pelayanaan Akademik) dan Variabel Y (Kepuasan Mahasiswa

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Struecker, Klaus Almeida. "AS DIVERGÊNCIAS ENTRE MUNICÍPIOS E CONTRIBUINTES NA ESTIPULAÇÃO DA BASE DE CÁLCULO DO ITBI EM IMÓVEIS ADQUIRIDOS POR MEIO DE LEILÕES JUDICIAIS E EXTRAJUDICIAIS." Revista de Direito Tributário e Financeiro 7, no. 1 (2021): 44. http://dx.doi.org/10.26668/indexlawjournals/2526-0138/2021.v7i1.7723.

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O foco do presente trabalho é a conjuntura tributária, especificamente quanto à demonstração de que a base de cálculo do ITBI é o valor alcançado em leilão na compra e venda de um imóvel adquirido por meio de hasta pública. O ITBI é o Imposto de Transmissão de Bens Imóveis, um tributo municipal aplicado sobre transferências imobiliárias. A responsabilidade do pagamento do tributo costuma obedecer às leis municipais. No caso de bem adquirido em hasta pública, verifica-se que o ITBI deve ser calculado sobre o preço pago pelo arrematante e não sobre o valor de mercado.

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Carneiro, Filipe Lima Rios. "O IMPOSTO SOBRE A TRANSMISSÃO DE BENS IMÓVEIS E A SUA INCIDÊNCIA QUANDO DA AQUISIÇÃO DE TERRENOS PARA CONSTRUÇÃO FUTURA E IMÓVEIS NA PLANTA NO MUNICÍPIO DE BELO HORIZONTE." Revista de Direito Tributário e Financeiro 4, no. 1 (2018): 18. http://dx.doi.org/10.26668/indexlawjournals/2526-0138/2018.v4i1.4400.

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Este artigo abordará a estrutura do Imposto sobre a Transmissão de Bens Imóveis – ITBI, passando pela Teoria Geral do Direito Tributário, notadamente pelos aspectos da Hipótese de Incidência, utilizando-se como marco teórico o livro Hipótese de Incidência Tributária de Geraldo Ataliba. Com base nessa abordagem será analisada a compatibilidade das cobranças de ITBI e ITBI complementar com multa e juros realizadas pelo Município de Belo Horizonte em casos de aquisição de terreno para realização de futura edificação e aquisição de unidades imobiliárias autônomas para entrega futura, com aqueles e

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Nagao, Azusa, Keiji Nogami, Nobuaki Suzuki, et al. "Emicizumab and Immune Tolerance Induction in People with Hemophilia A and Factor VIII Inhibitors: 96-Week Interim Analysis of the AKATSUKI Study." Blood 144, Supplement 1 (2024): 2588. https://doi.org/10.1182/blood-2024-193535.

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Introduction: Immune tolerance induction (ITI) therapy is indicated for people with hemophilia A (PwHA) to eradicate factor (F)VIII inhibitors. The safety of emicizumab treatment in combination with ITI requires further exploration. This study aims to evaluate the safety of emicizumab during and immediately after ITI. Methods: AKATSUKI (jRCTs041200037) is a Phase IV, open-label, non-randomized, interventional, multicenter study in Japan. PwHA were included if they had a positive FVIII inhibitor titer (≥0.6 BU/mL) and were starting ITI following enrollment, or had undergone ITI, but had not ach

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Vanover, Kimberly, Gretchen Snyder, Joseph Hendrick, et al. "ITI-007." International Clinical Psychopharmacology 26 (September 2011): e56. http://dx.doi.org/10.1097/01.yic.0000405728.69382.1e.

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Ahsan, N. "Intravenous infusion of total dose iron is superior to oral iron in treatment of anemia in peritoneal dialysis patients: a single center comparative study." Journal of the American Society of Nephrology 9, no. 4 (1998): 664–68. http://dx.doi.org/10.1681/asn.v94664.

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In the treatment of anemia of chronic renal failure, the most common cause of recombinant human erythropoietin (rhEPO) resistance is iron deficiency. In peritoneal dialysis (PD) patients, oral iron therapy is an accepted and convenient method of iron supplementation. The effectiveness of oral iron, however, is limited by many factors, including gastrointestinal side effects and poor gastric absorption. This study prospectively compared the efficacy of single intravenous infusion of total dose iron (ITDI group) given in an outpatient setting with oral iron (oral group) for the treatment of anem

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Xu, Zhen Hui, Jun Yang, Wan Jun Zhang, and Zhen Jun Yang. "Regions of Interest Detection Algorithm Based on Improved Visual Attention Model." Applied Mechanics and Materials 513-517 (February 2014): 3368–71. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.3368.

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Regions of Interest (ROI) detection algorithm based on Visual Attention Model can rapidly focus the attention in the conspicuous target region, and extract the interested region. As to some complicated scenes, it is very difficult to detect the target accurately by using general target detecting method, but using Regions of Interest detection algorithm based on Itti Visual Attention Model can detect the target position very well. But pay attention to Itti Visual Attention Model, it utilizes the luminance, color and texture character of the target to detect the position of it. As little moving

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Li, Nanxin, Koo Wilson, Marc Botteman, Daniel Nicoloso, Sangeeta Krishnan, and Jun Su. "Economic Impact of Immune Tolerance Induction (ITI) with Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) Compared to Conventional Recombinant Factor VIII (rFVIII)." Blood 132, Supplement 1 (2018): 3520. http://dx.doi.org/10.1182/blood-2018-99-114993.

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Abstract Introduction: Hemophilia A results from a clotting protein factor VIII (FVIII) deficiency, which leads to the need for the use of exogenous FVIII. Such therapy is effective unless alloantibodies (inhibitors) develop and render FVIII replacement ineffective. Patients with high-titer inhibitors may try to eradicate the presence of these inhibitors by undergoing ITI, an often costly process that requires the prolonged use of frequent doses of FVIII to induce FVIII antigen-specific tolerance. There is no consensus on the best approach to achieve tolerance and no product has been approved

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KACZMAREK, ŁUKASZ, and ŁUKASZ MICHALCZYK. "Thulinius itoi comb. nov. a new systematic position for Isohypsibius itoi (Tsurusaki, 1980) (Tardigrada: Eutardigrada: Hypsibiidae)." Zootaxa 1373, no. 1 (2006): 65. http://dx.doi.org/10.11646/zootaxa.1373.1.4.

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Thulinius itoi comb. nov. described by Nobuo Tsurusaki in 1980 as Hypsibius (Isohypsibius) itoi from interstitial habitat in Japan and transferred to the genus Isohypsibius by Ramazzotti and Maucci (1983) is re-examined and transferred to the genus Thulinius based on the morphology of bucco-pharyngeal apparatus.

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Jimi, S., A. Takaki, S. Takebayashi, and M. Segawa. "Mitochondrial DNA deletion of proximal tubules is the result of itai-itai disease." Clinical and Experimental Nephrology 7, no. 1 (2003): 18–26. http://dx.doi.org/10.1007/s101570300002.

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Yoshida, Fumikazu, Akio Hata, and Haruo Tonegawa. "Itai-Itai disease and the countermeasures against cadmium pollution by the Kamioka mine." Environmental Economics and Policy Studies 2, no. 3 (1999): 215–29. http://dx.doi.org/10.1007/bf03353912.

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Prezotti, Alessandra Nunes Loureiro, Silmara Aparecida De Lima Montalvão, Cláudia Lorenzato, et al. "Immune Tolerance Induction Treatment Is Cost-Effective in Adult Patients with Long-Standing High-Responding Inhibitors." Blood 126, no. 23 (2015): 3530. http://dx.doi.org/10.1182/blood.v126.23.3530.3530.

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Abstract Introduction: Despite treatment of hemophilia having achieved considerable improvement over the last decades, inhibitor development remains a major complication for these patients. Inhibitors are alloantibodies that neutralize factor (F) VIII coagulation activity, and occur in approximately 25% of hemophilia A patients. Immune tolerance induction (ITI) is the choice therapy to eradicate these antibodies. There are several ITI protocols with similar success rates, approximately 70%. The presence of long-standing inhibitors in the adult population has usually been associated with poor I

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Nakar, Charles T., Marilyn J. Manco-Johnson, Alice Lail, et al. "Prompt Immune Tolerance Induction at Inhibitor Diagnosis Regardless of Titer May Increase Overall Success in Hemophilia A With Inhibitors: Experience of Two US Centers." Blood 122, no. 21 (2013): 575. http://dx.doi.org/10.1182/blood.v122.21.575.575.

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Abstract Introduction Immune tolerance induction (ITI) for patients (pts) with hemophilia A with inhibitors is the only modality known to effectively eradicate inhibitors with an overall reported success of ∼60-80%. One debate concerns the optimal time to start ITI; recent guidelines recommend delaying ITI until inhibitor titer is <10 Bethesda units (BU). Aim We report results of an analytic project to determine the success of ITI relative to time from inhibitor detection to ITI initiation. Methods Data was collected retrospectively at 2 US hemophilia centers on pts with severe/moderate (≤5

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Li, Zhengping, and Runhui Wu. "Chinese Severe Hemophilia a Children with High-Titer Inhibitors Obtain More Benefit from Intermediate-Dose Immune Tolerance Induction: The Interim Result of Lome Part a." Blood 142, Supplement 1 (2023): 5478. http://dx.doi.org/10.1182/blood-2023-185290.

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Background We previously showed that low-dose immune tolerance induction (LD-ITI) strategy [incorporating immunosuppressants (IS) partially] for severe hemophilia A (SHA) patients with high-titer inhibitors (HTI) had relatively equivalent success rate with lower cost compared to those on high-dose ITI from international (I)-ITI randomized clinical trial (RCT). However, it is lack of RCT to compare the efficacy, safety, and cost of LD-ITI strategy to higher-dose ITI [intermediate-dose (MD)-ITI] strategy in China. Currently, the domestic recombinant FVIII (rFVIII) sponsored by the SinoCelltech L

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