Academic literature on the topic 'ITGA7'

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Journal articles on the topic "ITGA7"

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Park, Hye Jin, Ji Eun Park, Hyun Lee, et al. "Integrins functioning in uterine endometrial stromal and epithelial cells in estrus." Reproduction 153, no. 3 (2017): 351–60. http://dx.doi.org/10.1530/rep-16-0516.

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Here, as a basic study in the construction of a non-cellular niche that supports artificial organization of three-dimensional endometrial tissue, we defined the types of integrin heterodimers that are expressed transcriptionally, translationally and functionally in endometrial stromal (ES) and endometrial epithelial (EE) cells isolated from the mouse uterus in estrus. Gene and protein expression of integrin subunits were analyzed at the transcriptional and translational level by real-time PCR and fluorescent immunoassay, respectively. Moreover, the functionality of integrin heterodimers was co
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Xu, D., T. Li, and R. Mu. "AB0095 EXPRESSION AND PATHOGENIC ROLES OF INTEGRIN FAMILY GENE IN SYSTEMIC SCLEROSIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1076.2–1076. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3646.

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Background:Emerging evidence have shown that some integrin members are associated with inflammation and fibrosis in systemic sclerosis (SSc) patients[1-2]. However, the expression patterns and pathogenic significance of the whole integrin family in SSc are still unclear.Objectives:This study aimed at evaluating the integrin family gene expression in skin lesion from SSc patients and exploring its potential pathogenic mechanism.Methods:We utilized the public datasets of SSc skin tissue from Gene Expression Omnibus (GEO) database to analyze the expression and clinical significance of integrin fa
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Ратушный, А. Ю., та Л. Б. Буравкова. "ЭКСПРЕССИЯ ГЕНОВ ФОКАЛЬНОЙ АДГЕЗИИ В МУЛЬТИПОТЕНТНЫХ МЕЗЕНХИМАЛЬНЫХ СТРОМАЛЬНЫХ КЛЕТКАХ ПРИ МОДЕЛИРОВАНИИ ЭФФЕКТОВ МИКРОГРАВИТАЦИИ, "Доклады Академии наук"". Доклады Академии Наук, № 1 (2017): 106–8. http://dx.doi.org/10.7868/s086956521731022x.

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Исследовали экспрессию 84 генов фокальной адгезии мультипотентных мезенхимальных стромальных клеток (ММСК) после 96-часового моделирования эффектов микрогравитации при 3D-клиностатировании. Обнаружили повышение экспрессии ITGA6, ITGA7, BCAR1, GRB2, CAV1, DIAPH1 и снижение ITGA11, ITGAV, ITGB1, PTEN, PTK2 (FAK), ARHGAP5, DOCK1, ROCK2, AKT3. Эти изменения на транскрипционном уровне могут быть одной из причин снижения остеогенного потенциала ММСК и их способности к миграции и адгезии в условиях микрогравитации.
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Takahashi, Toshiaki, Florian Friedmacher, Julia Zimmer та Prem Puri. "Decreased Expression of Integrin Subunits α3, α6, and α8 in the Branching Airway Mesenchyme of Nitrofen-Induced Hypoplastic Lungs". European Journal of Pediatric Surgery 28, № 01 (2017): 109–14. http://dx.doi.org/10.1055/s-0037-1604022.

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Introduction Pulmonary hypoplasia (PH), characterized by smaller lung size and reduced airway branching, remains a major cause of neonatal mortality in newborns with congenital diaphragmatic hernia (CDH). Integrin-mediated cell–matrix interactions play an essential role in the fetal lung mesenchyme by stimulating branching morphogenesis. Mice lacking integrin subunits α3 (Itga3) and α6 (Itga6) exhibit severe PH. Furthermore, Itga8-knockout mice show defective airway branching, suggesting that Itga3, Itga6, and Itga8 are crucial for fetal lung development. We hypothesized that expression of Itg
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Guan, Yaoyao, Adheesh Bhandari, Erjie Xia, Lingguo Kong, Xiaohua Zhang, and Ouchen Wang. "Downregulating integrin subunit alpha 7 (ITGA7) promotes proliferation, invasion, and migration of papillary thyroid carcinoma cells through regulating epithelial-to-mesenchymal transition." Acta Biochimica et Biophysica Sinica 52, no. 2 (2020): 116–24. http://dx.doi.org/10.1093/abbs/gmz144.

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Abstract Thyroid cancer is one of the common malignancies of the endocrine system and the number of thyroid cancer cases is increasing constantly. Significant work has focused on the molecular mechanisms of thyroid cancer, but many mechanisms remain undiscovered. In this study, we employed a comprehensive analysis of whole-transcriptome resequencing derived from paired papillary thyroid cancer (PTC) and normal thyroid tissues. We performed a massive parallel whole-transcriptome resequencing of matched PTC and normal thyroid tissues in 19 patients and found that integrin subunit alpha 7 (ITGA7)
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Takashima, Yasuo, Atsushi Kawaguchi, Junya Fukai, et al. "Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma." PLOS ONE 16, no. 6 (2021): e0251272. http://dx.doi.org/10.1371/journal.pone.0251272.

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Dysregulation of cell morphology and cell-cell interaction results in cancer cell growth, migration, invasion, and metastasis. Besides, a balance between the extracellular matrix (ECM) and matrix metalloprotease (MMP) is required for cancer cell morphology and angiogenesis. Here, we determined gene signatures associated with the morphology and microenvironment of primary central nervous system lymphoma (PCNSL) to enable prognosis prediction. Next-generation sequencing (NGS) on 31 PCNSL samples revealed gene signatures as follows: ACTA2, ACTR10, CAPG, CORO1C, KRT17, and PALLD in cytoskeleton, C
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Kobayashi, Nobuhiko, Tsukasa Oda, Makiko Takizawa та ін. "Integrin α7 and Extracellular Matrix Laminin 211 Interaction Promotes Proliferation of Acute Myeloid Leukemia Cells and Is Associated with Granulocytic Sarcoma". Cancers 12, № 2 (2020): 363. http://dx.doi.org/10.3390/cancers12020363.

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Acute myeloid leukemia (AML) with granulocytic sarcoma (GS) is characterized by poor prognosis; however, its underlying mechanism is unclear. Bone marrow samples from 64 AML patients (9 with GS and 55 without GS) together with AML cell lines PL21, THP1, HL60, Kasumi-1, and KG-1 were used to elucidate the pathology of AML with GS. RNA-Seq analyses were performed on samples from seven AML patients with or without GS. Gene set enrichment analyses revealed significantly upregulated candidates on the cell surface of the GS group. Expression of the adhesion integrin α7 (ITGA7) was significantly high
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Chidlow, John H., John D. Glawe, J. Steven Alexander, and Christopher G. Kevil. "VEGF164 differentially regulates neutrophil and T cell adhesion through ItgaL- and ItgaM-dependent mechanisms." American Journal of Physiology-Gastrointestinal and Liver Physiology 299, no. 6 (2010): G1361—G1367. http://dx.doi.org/10.1152/ajpgi.00202.2010.

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Leukocyte recruitment to inflamed tissues is the cornerstone of inflammatory responses and the driving force behind the establishment of inflammatory bowel disease, consisting of Crohn's disease and ulcerative colitis. It has been reported that angiogenic cytokines contribute to this inflammatory response that facilitates the chronic nature of disease. We have previously reported (Goebel S, Huang M, Davis WC, Jennings M, Siahaan TJ, Alexander JS, Kevil CG. Am J Physiol Gastrointest Liver Physiol 290: G648–G654, 2006) that vascular endothelial growth factor (VEGF)-A can stimulate neutrophil adh
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Tang, Jia, and Takashi Saito. "The Role of Nephronectin on Proliferation and Differentiation in Human Dental Pulp Stem Cells." Stem Cells International 2017 (November 19, 2017): 1–14. http://dx.doi.org/10.1155/2017/2546261.

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Aim. The purpose of the current study was to investigate the effects of nephronectin (Npnt) in human dental pulp stem cells (hDPSCs). Methodology. Npnt was coated to nontissue culture-treated polystyrene (non-PS) plates. The presence of immobilized protein on the surface was detected by polyclonal rabbit primary anti-Npnt antibody. Then the cell number was counted and compared with PBS-, bovine serum albumin- (BSA-), fish scale type I collagen- (FCOL1-), and human fibronectin- (Fn-) coated wells. Cell proliferation was assessed using CCK-8 assay. Cell morphology was observed under light micros
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Skov, Vibe, Mads Thomassen, Lasse Kjær, et al. "Extracellular Matrix-Related Genes Are Deregulated in Peripheral Blood from Patients with Myelofibrosis and Related Neoplasms." Blood 132, Supplement 1 (2018): 5491. http://dx.doi.org/10.1182/blood-2018-99-117122.

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Abstract Introduction: The Philadelphia-negative chronic myeloproliferative neoplasms (MPNs) which include essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF) are characterized by varying degrees of bone marrow fibrosis and endothelial proliferation. We and others have previously reported that these stromal alterations are reflected by increased serum levels of matrix derived metabolites, striated collagens type I/III and basement membrane components. The existence of a prefibrotic seromarker profile in MPNs is further evidenced by reports on increased serum
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Dissertations / Theses on the topic "ITGA7"

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Heller, Kristin Noreen. "Alternative to Gene Replacement for Duchenne Muscular Dystrophy using Human Alpha7 Integrin (ITGA7)." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1388401639.

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Hsieh, Jenny [Verfasser], Rolf [Akademischer Betreuer] Marschalek, and Theodor [Akademischer Betreuer] Dingermann. "Funktionelle Analyse des MLH1·ITGA9-Fusionsproteins einer Lynch-Syndrom-Familie / Jenny Hsieh. Gutachter: Rolf Marschalek ; Theodor Dingermann. Betreuer: Rolf Marschalek." Frankfurt am Main : Univ.-Bibliothek Frankfurt am Main, 2012. http://d-nb.info/1044093447/34.

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Mokrani, M'barka. "CD103 : du gène à la protéine : Etude de la régulation et de la signalisation de l’intégrine αE(CD103)β7 exprimée par les lymphocytes T CD8+ intratumoraux". Thesis, Paris 11, 2013. http://www.theses.fr/2013PA11T071.

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L’élucidation des mécanismes permettant l’optimisation de la réponse immunitaire antitumorale correspond à un enjeu majeur pour le développement de stratégies d’immunothérapie efficace. En effet, les réponses immunitaires antitumorales se traduisent rarement par l’éradication de la tumeur. Dans ce contexte, les travaux antérieurs de mon équipe ont démontré que l’interaction de l’intégrine αE(CD103)β7, souvent exprimée par les lymphocytes infiltrant la tumeur (TIL), avec son ligand E-cadhérine, à la surface des cellules tumorales épithéliales, joue un rôle majeur dans la potentialisation de l’a
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Holtkötter, Olaf. "Inaktivierung des ITGA2-Gens in der Maus neue Erkenntnisse über die Funktion des [alpha]2[beta]1-Integrinrezeptors [alpha2beta1-Integrinrezeptors] in vivo /." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=966631803.

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Leibnitz, Alexander [Verfasser], Oliver [Akademischer Betreuer] Gross, and Wolfgang [Akademischer Betreuer] Krick. "Einfluss der Kollagenrezeptoren ITGA2 und DDR1 in der Pathogenese von glomerulären Nierenerkrankungen am Doppelknockout-Tiermodell / Alexander Leibnitz. Gutachter: Oliver Gross ; Wolfgang Krick. Betreuer: Oliver Gross." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2014. http://d-nb.info/1051977223/34.

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Talbot, Jared Coffin 1982. "Patterning and Stabilizing the Zebrafish Pharyngeal Arch Intermediate Domain." Thesis, University of Oregon, 2011. http://hdl.handle.net/1794/11982.

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xv, 76 p. : ill. (some col.) Includes 4 video files.<br>Improved understanding of pharyngeal arch (PA) patterning and morphogenesis can reveal critical insights into the origins of craniofacial diseases, such as Fraser syndrome. PAs contain mesenchymal condensations, which give rise to most of the facial skeleton in vertebrates. Studies of Endothelin1 signaling reveal that the skeleton derived from the first two PAs are patterned into dorsal, intermediate, and ventral domains. Previous work has indicated that endothelin targets, including the Dlx genes, homeotically pattern dorsal versus ventr
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Masià, Fontana Anna. "El papel de la vía Notch en Rabdomiosarcoma." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/121513.

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El Rabdomiosarcoma (RMS) es el tumor de partes blandas más común en la infancia. Los pacientes con enfermedad diseminada continúan teniendo un mal pronóstico a pesar del uso de terapias intensivas. En este trabajo se evidencia la expresión y activación notable de la vía Notch en RMS y se demuestra la implicación de la vía como elemento clave en la regulación de mecanismos de adhesividad, movilidad e invasividad en células de RMS. Además se propone un mecanismo de regulación de estos procesos, mediado por Notch, a través de la regulación positiva de varias moléculas de adhesión, tales como la
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Li, Yen Liang, and 黎彥良. "Transcriptomic analyses identify ITGA6 and GDF15 contributing to radioresistance in head-neck cancer." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/67486930570333855678.

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Leibnitz, Alexander. "Einfluss der Kollagenrezeptoren ITGA2 und DDR1 in der Pathogenese von glomerulären Nierenerkrankungen am Doppelknockout-Tiermodell." Doctoral thesis, 2014. http://hdl.handle.net/11858/00-1735-0000-0022-5EA7-8.

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Die Mehrheit chronischer Nierenerkrankungen wird durch glomeruläre Defekte hervorgerufen. In dieser Arbeit wurde deshalb im Mausmodell die Bedeutung der Kollagenrezeptoren DDR1 (Discoidin Domain Rezeptor 1) und ITGA2 (Integrin Alpha 2) in der Pathogenese von glomerulären Nierenerkrankungen untersucht. Von zentralem Interesse waren neben der Betrachtung des renalen Phänotyps, die Analyse der glomerulären Basalmembran sowie die Prüfung auf Vorhandensein nierenschädigender Faktoren. Zur Orientierung angefertigte H.E.-Färbungen waren lichtmikroskopisch unauffällig, jedoch ließ sich mittels Gelelek
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Yu, Chun-Wei, and 游淳惟. "Using Bioinformatics Tools to Design an Anti-ITGA2 Antibody for Inhibiting Gastric Cancer Cell Growth." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/86994073822041533142.

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Books on the topic "ITGA7"

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Lewis, Myles, and Tim Vyse. Genetics of connective tissue diseases. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0042.

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The advent of genome-wide association studies (GWAS) has been an exciting breakthrough in our understanding of the genetic aetiology of autoimmune diseases. Substantial overlap has been found in susceptibility genes across multiple diseases, from connective tissue diseases and rheumatoid arthritis (RA) to inflammatory bowel disease, coeliac disease, and psoriasis. Major technological advances now permit genotyping of millions of single nucleotide polymorphisms (SNPs). Group analysis of SNPs by haplotypes, aided by completion of the Hapmap project, has improved our ability to pinpoint causal ge
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Book chapters on the topic "ITGA7"

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Appleton, Kathryn M., Ian Cushman, Yuri K. Peterson, et al. "Itga4." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100673.

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Appleton, Kathryn M., Ian Cushman, Yuri K. Peterson, et al. "Integrin α2 (ITGA2)." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_238.

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Appleton, Kathryn M., Ian Cushman, Yuri K. Peterson, et al. "Integrin α1 (ITGA1)." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_556.

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Heino, Jyrki. "Integrin α2 (ITGA2)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_238.

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Heino, Jyrki. "Integrin α1 (ITGA1)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_556.

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Heino, Jyrki. "Integrin α2 (ITGA2)." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_238-1.

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Heino, Jyrki. "Integrin α1 (ITGA1)." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_556-1.

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Appleton, Kathryn M., Ian Cushman, Yuri K. Peterson, et al. "Integrin Alpha V (ITGAV)." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_619.

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Kerr, Bethany A., and Tatiana V. Byzova. "Integrin Alpha V (ITGAV)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_619.

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Appleton, Kathryn M., Ian Cushman, Yuri K. Peterson, et al. "Integrin Alpha 4 (Itga 4)." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_143.

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Conference papers on the topic "ITGA7"

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Ming, Xiaoyan, Li Fu, Liyi Zhang, and Xinyuan Guan. "Abstract 3872: Identification and characterization of ITGA7 as cancer stem cell marker in esophageal squamous cell carcinoma (ESCC)." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3872.

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Peacock, Danielle L., Luciana P. Schwab, and Tiffany N. Seagroves. "Abstract 3885: ITGA6 (CD49F) is directly regulated by hypoxia-inducible factors." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3885.

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Niemeyer, L., C. Thon, J. Bornschein, J. Weigt, P. Malfertheiner, and A. Link. "Translationale Relevanz von ITGA5 Expression in präneoplastischen Magenveränderungen und H. pylori Infektion." In Viszeralmedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1695421.

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Epstein Shochet, G., E. Brook, E. Edelstein, O. Wand, D. A. King, and D. Shitrit. "Integrin A5 (ITGA5) Promotes Cellular Responses Facilitating Idiopathic Pulmonary Fibrosis (IPF) Progression." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5320.

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Yang, Heng-Yi, and Tian-Ni Mao. "ITGAX: A Potential Biomarker of Acute Myeloid Leukemia (AML) through Bioinformatic Analysis." In 2021 IEEE 9th International Conference on Bioinformatics and Computational Biology (ICBCB). IEEE, 2021. http://dx.doi.org/10.1109/icbcb52223.2021.9459204.

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Nunez, Nomeli P. "Abstract A100: Alcohol promotes breast cancer cell invasion by regulating the Nm23-ITGA5 pathway." In Abstracts: AACR International Conference on the Science of Cancer Health Disparities‐‐ Sep 30-Oct 3, 2010; Miami, FL. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1055-9965.disp-10-a100.

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Horton, Richard F. "A Family of 2 Mirror Unobscured Wide Field Telescope & Collimator Designs." In International Optical Design Conference. OSA, 2010. http://dx.doi.org/10.1364/iodc.2010.itua7.

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Sullivan, Amy C., and Robert R. McLeod. "3D Tapered Waveguides in Volume Photopolymers." In Integrated Photonics and Nanophotonics Research and Applications. OSA, 2007. http://dx.doi.org/10.1364/ipnra.2007.itua7.

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Balykin, Victor I., Fam Le Kien, J. Q. Liang, Makoto Morinaga, and K. Hakuta. "Atom spinning around an optical fiber: Bound states and guiding." In International Quantum Electronics Conference. OSA, 2004. http://dx.doi.org/10.1364/iqec.2004.itua7.

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Rutter, Natalia B., Sergey V. Polyakov, Paul Lett, and Alan Migdall. "Single-Photon Traversal of Dielectric Stacks." In International Quantum Electronics Conference. OSA, 2009. http://dx.doi.org/10.1364/iqec.2009.itha7.

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