Log in

Relevant bibliographies by topics / ITGA7 / Journal articles

To see the other types of publications on this topic, follow the link: ITGA7.

Journal articles on the topic 'ITGA7'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'ITGA7.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Park, Hye Jin, Ji Eun Park, Hyun Lee, et al. "Integrins functioning in uterine endometrial stromal and epithelial cells in estrus." Reproduction 153, no. 3 (2017): 351–60. http://dx.doi.org/10.1530/rep-16-0516.

Full text

Abstract:

Here, as a basic study in the construction of a non-cellular niche that supports artificial organization of three-dimensional endometrial tissue, we defined the types of integrin heterodimers that are expressed transcriptionally, translationally and functionally in endometrial stromal (ES) and endometrial epithelial (EE) cells isolated from the mouse uterus in estrus. Gene and protein expression of integrin subunits were analyzed at the transcriptional and translational level by real-time PCR and fluorescent immunoassay, respectively. Moreover, the functionality of integrin heterodimers was co

APA, Harvard, Vancouver, ISO, and other styles

2

Xu, D., T. Li, and R. Mu. "AB0095 EXPRESSION AND PATHOGENIC ROLES OF INTEGRIN FAMILY GENE IN SYSTEMIC SCLEROSIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1076.2–1076. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3646.

Full text

Abstract:

Background:Emerging evidence have shown that some integrin members are associated with inflammation and fibrosis in systemic sclerosis (SSc) patients[1-2]. However, the expression patterns and pathogenic significance of the whole integrin family in SSc are still unclear.Objectives:This study aimed at evaluating the integrin family gene expression in skin lesion from SSc patients and exploring its potential pathogenic mechanism.Methods:We utilized the public datasets of SSc skin tissue from Gene Expression Omnibus (GEO) database to analyze the expression and clinical significance of integrin fa

APA, Harvard, Vancouver, ISO, and other styles

3

Ратушный, А. Ю., та Л. Б. Буравкова. "ЭКСПРЕССИЯ ГЕНОВ ФОКАЛЬНОЙ АДГЕЗИИ В МУЛЬТИПОТЕНТНЫХ МЕЗЕНХИМАЛЬНЫХ СТРОМАЛЬНЫХ КЛЕТКАХ ПРИ МОДЕЛИРОВАНИИ ЭФФЕКТОВ МИКРОГРАВИТАЦИИ, "Доклады Академии наук"". Доклады Академии Наук, № 1 (2017): 106–8. http://dx.doi.org/10.7868/s086956521731022x.

Full text

Abstract:

Исследовали экспрессию 84 генов фокальной адгезии мультипотентных мезенхимальных стромальных клеток (ММСК) после 96-часового моделирования эффектов микрогравитации при 3D-клиностатировании. Обнаружили повышение экспрессии ITGA6, ITGA7, BCAR1, GRB2, CAV1, DIAPH1 и снижение ITGA11, ITGAV, ITGB1, PTEN, PTK2 (FAK), ARHGAP5, DOCK1, ROCK2, AKT3. Эти изменения на транскрипционном уровне могут быть одной из причин снижения остеогенного потенциала ММСК и их способности к миграции и адгезии в условиях микрогравитации.

APA, Harvard, Vancouver, ISO, and other styles

4

Takahashi, Toshiaki, Florian Friedmacher, Julia Zimmer та Prem Puri. "Decreased Expression of Integrin Subunits α3, α6, and α8 in the Branching Airway Mesenchyme of Nitrofen-Induced Hypoplastic Lungs". European Journal of Pediatric Surgery 28, № 01 (2017): 109–14. http://dx.doi.org/10.1055/s-0037-1604022.

Full text

Abstract:

Introduction Pulmonary hypoplasia (PH), characterized by smaller lung size and reduced airway branching, remains a major cause of neonatal mortality in newborns with congenital diaphragmatic hernia (CDH). Integrin-mediated cell–matrix interactions play an essential role in the fetal lung mesenchyme by stimulating branching morphogenesis. Mice lacking integrin subunits α3 (Itga3) and α6 (Itga6) exhibit severe PH. Furthermore, Itga8-knockout mice show defective airway branching, suggesting that Itga3, Itga6, and Itga8 are crucial for fetal lung development. We hypothesized that expression of Itg

APA, Harvard, Vancouver, ISO, and other styles

5

Guan, Yaoyao, Adheesh Bhandari, Erjie Xia, Lingguo Kong, Xiaohua Zhang, and Ouchen Wang. "Downregulating integrin subunit alpha 7 (ITGA7) promotes proliferation, invasion, and migration of papillary thyroid carcinoma cells through regulating epithelial-to-mesenchymal transition." Acta Biochimica et Biophysica Sinica 52, no. 2 (2020): 116–24. http://dx.doi.org/10.1093/abbs/gmz144.

Full text

Abstract:

Abstract Thyroid cancer is one of the common malignancies of the endocrine system and the number of thyroid cancer cases is increasing constantly. Significant work has focused on the molecular mechanisms of thyroid cancer, but many mechanisms remain undiscovered. In this study, we employed a comprehensive analysis of whole-transcriptome resequencing derived from paired papillary thyroid cancer (PTC) and normal thyroid tissues. We performed a massive parallel whole-transcriptome resequencing of matched PTC and normal thyroid tissues in 19 patients and found that integrin subunit alpha 7 (ITGA7)

APA, Harvard, Vancouver, ISO, and other styles

6

Takashima, Yasuo, Atsushi Kawaguchi, Junya Fukai, et al. "Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma." PLOS ONE 16, no. 6 (2021): e0251272. http://dx.doi.org/10.1371/journal.pone.0251272.

Full text

Abstract:

Dysregulation of cell morphology and cell-cell interaction results in cancer cell growth, migration, invasion, and metastasis. Besides, a balance between the extracellular matrix (ECM) and matrix metalloprotease (MMP) is required for cancer cell morphology and angiogenesis. Here, we determined gene signatures associated with the morphology and microenvironment of primary central nervous system lymphoma (PCNSL) to enable prognosis prediction. Next-generation sequencing (NGS) on 31 PCNSL samples revealed gene signatures as follows: ACTA2, ACTR10, CAPG, CORO1C, KRT17, and PALLD in cytoskeleton, C

APA, Harvard, Vancouver, ISO, and other styles

7

Kobayashi, Nobuhiko, Tsukasa Oda, Makiko Takizawa та ін. "Integrin α7 and Extracellular Matrix Laminin 211 Interaction Promotes Proliferation of Acute Myeloid Leukemia Cells and Is Associated with Granulocytic Sarcoma". Cancers 12, № 2 (2020): 363. http://dx.doi.org/10.3390/cancers12020363.

Full text

Abstract:

Acute myeloid leukemia (AML) with granulocytic sarcoma (GS) is characterized by poor prognosis; however, its underlying mechanism is unclear. Bone marrow samples from 64 AML patients (9 with GS and 55 without GS) together with AML cell lines PL21, THP1, HL60, Kasumi-1, and KG-1 were used to elucidate the pathology of AML with GS. RNA-Seq analyses were performed on samples from seven AML patients with or without GS. Gene set enrichment analyses revealed significantly upregulated candidates on the cell surface of the GS group. Expression of the adhesion integrin α7 (ITGA7) was significantly high

APA, Harvard, Vancouver, ISO, and other styles

8

Chidlow, John H., John D. Glawe, J. Steven Alexander, and Christopher G. Kevil. "VEGF164 differentially regulates neutrophil and T cell adhesion through ItgaL- and ItgaM-dependent mechanisms." American Journal of Physiology-Gastrointestinal and Liver Physiology 299, no. 6 (2010): G1361—G1367. http://dx.doi.org/10.1152/ajpgi.00202.2010.

Full text

Abstract:

Leukocyte recruitment to inflamed tissues is the cornerstone of inflammatory responses and the driving force behind the establishment of inflammatory bowel disease, consisting of Crohn's disease and ulcerative colitis. It has been reported that angiogenic cytokines contribute to this inflammatory response that facilitates the chronic nature of disease. We have previously reported (Goebel S, Huang M, Davis WC, Jennings M, Siahaan TJ, Alexander JS, Kevil CG. Am J Physiol Gastrointest Liver Physiol 290: G648–G654, 2006) that vascular endothelial growth factor (VEGF)-A can stimulate neutrophil adh

APA, Harvard, Vancouver, ISO, and other styles

9

Tang, Jia, and Takashi Saito. "The Role of Nephronectin on Proliferation and Differentiation in Human Dental Pulp Stem Cells." Stem Cells International 2017 (November 19, 2017): 1–14. http://dx.doi.org/10.1155/2017/2546261.

Full text

Abstract:

Aim. The purpose of the current study was to investigate the effects of nephronectin (Npnt) in human dental pulp stem cells (hDPSCs). Methodology. Npnt was coated to nontissue culture-treated polystyrene (non-PS) plates. The presence of immobilized protein on the surface was detected by polyclonal rabbit primary anti-Npnt antibody. Then the cell number was counted and compared with PBS-, bovine serum albumin- (BSA-), fish scale type I collagen- (FCOL1-), and human fibronectin- (Fn-) coated wells. Cell proliferation was assessed using CCK-8 assay. Cell morphology was observed under light micros

APA, Harvard, Vancouver, ISO, and other styles

10

Skov, Vibe, Mads Thomassen, Lasse Kjær, et al. "Extracellular Matrix-Related Genes Are Deregulated in Peripheral Blood from Patients with Myelofibrosis and Related Neoplasms." Blood 132, Supplement 1 (2018): 5491. http://dx.doi.org/10.1182/blood-2018-99-117122.

Full text

Abstract:

Abstract Introduction: The Philadelphia-negative chronic myeloproliferative neoplasms (MPNs) which include essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF) are characterized by varying degrees of bone marrow fibrosis and endothelial proliferation. We and others have previously reported that these stromal alterations are reflected by increased serum levels of matrix derived metabolites, striated collagens type I/III and basement membrane components. The existence of a prefibrotic seromarker profile in MPNs is further evidenced by reports on increased serum

APA, Harvard, Vancouver, ISO, and other styles

11

Lauritano, Dorina, Alberta Lucchese, Dario Di Stasio, et al. "Molecular Aspects of Drug-Induced Gingival Overgrowth: An In Vitro Study on Amlodipine and Gingival Fibroblasts." International Journal of Molecular Sciences 20, no. 8 (2019): 2047. http://dx.doi.org/10.3390/ijms20082047.

Full text

Abstract:

Gingival overgrowth is a serious side effect that accompanies the use of amlodipine. Several conflicting theories have been proposed to explain the fibroblast’s function in gingival overgrowth. To determine whether amlodipine alters the fibrotic response, we investigated its effects on treated gingival fibroblast gene expression as compared with untreated cells. Materials and Methods: Fibroblasts from ATCC® Cell Lines were incubated with amlodipine. The gene expression levels of 12 genes belonging to the “Extracellular Matrix and Adhesion Molecules” pathway was investigated in treated fibrobla

APA, Harvard, Vancouver, ISO, and other styles

12

Burghardt, Robert C., James R. Burghardt, James D. Taylor, et al. "Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal–conceptus interface and uterine wall during ovine pregnancy." REPRODUCTION 137, no. 3 (2009): 567–82. http://dx.doi.org/10.1530/rep-08-0304.

Full text

Abstract:

The integrity of the fetal–maternal interface is critical for proper fetal nourishment during pregnancy. Integrins are important adhesion molecules present at the interface during implantation; however,in vivoevidence for integrin activation and focal adhesion formation at the maternal–conceptus interface is limited. We hypothesized that focal adhesion assembly in uterine luminal epithelium (LE) and conceptus trophectoderm (Tr) results from integrin binding of extracellular matrix (ECM) at this interface to provide increased tensile forces and signaling to coordinate utero-placental developmen

APA, Harvard, Vancouver, ISO, and other styles

13

Behrends, Jochen, Christian M. Karsten, Sonja Wilke, Astrid Röbke, and Andrea Kruse. "Identification of ITGA4/ITGB7 and ITGAE/ITGB7 Expressing Subsets of Decidual Dendritic-Like Cells Within Distinct Microdomains of the Pregnant Mouse Uterus1." Biology of Reproduction 79, no. 4 (2008): 624–32. http://dx.doi.org/10.1095/biolreprod.107.067041.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Yang, Guangpu, Tianhao Zhang, Jinning Ye, et al. "Circ-ITGA7 sponges miR-3187-3p to upregulate ASXL1, suppressing colorectal cancer proliferation." Cancer Management and Research Volume 11 (July 2019): 6499–509. http://dx.doi.org/10.2147/cmar.s203137.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Liu, Jian, Zhe Zhang, Xiaowei Li, et al. "Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression." Oncogene 37, no. 41 (2018): 5477–91. http://dx.doi.org/10.1038/s41388-018-0355-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Pirulli, Doroti, Silvia Zezlina, Laura Vatta, et al. "A new polymorphism, g119A>G, in the integrin alpha 7 (ITGA7) gene." Human Mutation 16, no. 2 (2000): 180. http://dx.doi.org/10.1002/1098-1004(200008)16:2<180::aid-humu18>3.0.co;2-d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Cochrane, Lynne E., Katherine E. Tansey, Michael Gill, Louise Gallagher, and Richard J. L. Anney. "Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sample." Autism Research 3, no. 6 (2010): 342–44. http://dx.doi.org/10.1002/aur.157.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Lauritano, Dorina, Giulia Moreo, Luisa Limongelli, Annalisa Palmieri, and Francesco Carinci. "Drug-Induced Gingival Overgrowth: The Effect of Cyclosporin A and Mycophenolate Mophetil on Human Gingival Fibroblasts." Biomedicines 8, no. 7 (2020): 221. http://dx.doi.org/10.3390/biomedicines8070221.

Full text

Abstract:

Drug-induced gingival overgrowth may occur after a chronic administration of three classes of systemic drugs: Anticonvulsants, immunosuppressants, and calcium channel blockers. This study aimed to investigate how cyclosporin A and mycophenolate mophetil (immunosuppressive drugs) could interfere with human gingival fibroblasts functions, leading to gingival enlargement. Human gingival fibroblasts derived from the tissue of a 60-year-old female were cultured in a DMEME medium. A stock solution with 1 mg/mL of mycophenolate and 1 mg/mL of cyclosporine were prepared and dissolved in a DMEM medium

APA, Harvard, Vancouver, ISO, and other styles

19

Mautone, Lorenza, Carlo Ferravante, Anna Tortora, et al. "Higher Integrin Alpha 3 Beta1 Expression in Papillary Thyroid Cancer Is Associated with Worst Outcome." Cancers 13, no. 12 (2021): 2937. http://dx.doi.org/10.3390/cancers13122937.

Full text

Abstract:

Integrins are cell-extracellular matrix adhesion molecules whose expression level undergoes quantitative changes upon neoplastic transformation and are considered functionally related to the development of cancer metastasis. We analyzed the largest mRNA-seq dataset available to determine the expression pattern of integrin family subunits in papillary thyroid carcinomas (PTC). ITGA2, 3, 6, V, and ITGB1 integrin subunits were overexpressed in PTC compared to normal thyroid tissue. The PTC histology variants “classical” and “tall cell” displayed a similar integrin expression profile with a higher

APA, Harvard, Vancouver, ISO, and other styles

20

Shochet, Gali Epstein, Elizabetha Brook, Becky Bardenstein-Wald, et al. "Integrin alpha-5 silencing leads to myofibroblastic differentiation in IPF-derived human lung fibroblasts." Therapeutic Advances in Chronic Disease 11 (January 2020): 204062232093602. http://dx.doi.org/10.1177/2040622320936023.

Full text

Abstract:

Background and objective: The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerated amounts of extracellular matrix proteins and modifying cell microenvironment. As IPF-derived human lung fibroblasts (IPF-HLFs) were shown to express higher levels of integrin alpha-5 (ITGA5) than normal derived HLFs (N-HLFs), we explored the importance of ITGA5 to IPF progression. Methods: IPF-HLF and N-HLF primary cultures were established. ITGA5 wa

APA, Harvard, Vancouver, ISO, and other styles

21

Khan, Raiyan R., Valerio Napolioni, Andre Altmann, et al. "IDENTIFICATION OF AN ITGA7 VARIANT ASSOCIATED WITH ALZHEIMER’S DISEASE AND MULTIPLE OTHER NEURODEGENERATIVE DISEASES." Alzheimer's & Dementia 13, no. 7 (2017): P193—P194. http://dx.doi.org/10.1016/j.jalz.2017.07.050.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Hagedorn, Elliott J., Julie R. Perlin, Clara Mao, et al. "Genome-Wide RNA Tomography of the Hematopoietic Stem Cell Niche in Zebrafish Reveals Unexpected Functional Macrophage-Stem Cell Interactions." Blood 128, no. 22 (2016): 3882. http://dx.doi.org/10.1182/blood.v128.22.3882.3882.

Full text

Abstract:

Abstract The challenges of visualizing the mammalian bone marrow have precluded a rigorous analysis of the dynamic cell-cell interactions that control hematopoietic stem and progenitor cell (HSPC) engraftment. The transparent zebrafish embryo provides an unparalleled opportunity to directly visualize HSPC-niche cell interactions in live animals. To identify genes expressed in the zebrafish caudal hematopoietic tissue (CHT) - an embryonic niche akin to the mammalian fetal liver - we employed a new technique called tomo-seq (RNA tomography). By pairing cryosectioning with RNA-seq, this technolog

APA, Harvard, Vancouver, ISO, and other styles

23

COUSTET, BAPTISTE, SANDEEP K. AGARWAL, PRAVITT GOURH, et al. "Association Study of ITGAM, ITGAX, and CD58 Autoimmune Risk Loci in Systemic Sclerosis: Results from 2 Large European Caucasian Cohorts." Journal of Rheumatology 38, no. 6 (2011): 1033–38. http://dx.doi.org/10.3899/jrheum.101053.

Full text

Abstract:

Objective.Accumulating evidence shows that shared autoimmunity is critical for the pathogenesis of many autoimmune diseases. Systemic sclerosis (SSc) belongs to the connective tissue disorders, and recent data have highlighted strong associations with autoimmunity genes shared with other autoimmune diseases. To determine whether novel risk loci associated with systemic lupus erythematosus or multiple sclerosis may confer susceptibility to SSc, we tested single-nucleotide polymorphisms (SNP) from ITGAM, ITGAX, and CD58 for associations.Methods.SNP harboring associations with autoimmune diseases

APA, Harvard, Vancouver, ISO, and other styles

24

Bhandari, Adheesh, Erjie Xia, Yuying Zhou, et al. "ITGA7 functions as a tumor suppressor and regulates migration and invasion in breast cancer." Cancer Management and Research Volume 10 (May 2018): 969–76. http://dx.doi.org/10.2147/cmar.s160379.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Linhares, Marcelo Moura, Renato José Affonso, Luciano de Souza Viana, et al. "Genetic and Immunohistochemical Expression of Integrins ITGAV, ITGA6, and ITGA3 As Prognostic Factor for Colorectal Cancer: Models for Global and Disease-Free Survival." PLOS ONE 10, no. 12 (2015): e0144333. http://dx.doi.org/10.1371/journal.pone.0144333.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

McKnight, C. G., J. Meng, and L. J. Rosenwasser. "Polymorphisms of ITGAX and ITGAE Associated with Allergy Related Phenotypes." Journal of Allergy and Clinical Immunology 123, no. 2 (2009): S166. http://dx.doi.org/10.1016/j.jaci.2008.12.625.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Tang, Jia, and Takashi Saito. "A Novel Fragment Derived from Laminin-411 Facilitates Proliferation and Differentiation of Odontoblast-Like Cells." BioMed Research International 2018 (May 9, 2018): 1–10. http://dx.doi.org/10.1155/2018/9465383.

Full text

Abstract:

The aim for the present study was to evaluate the in vitro effects of iMatrix-411 in odontoblast-like cells. To that end, iMatrix-411 was coated to both nontissue culture treated- (Non-PS) and tissue culture treated-polystyrene (TCPS) multiwells. MDPC-23 cells were seeded into noncoated (control) or coated wells. Optimal coating density and cell proliferation were assessed by cell counting kit-8 (CCK-8) at day two, day three, and day five. Osteo/odontogenic differentiation was evaluated by real-time RT-PCR and alkaline phosphatase (ALP) activity at days seven and eight, respectively. Calcific

APA, Harvard, Vancouver, ISO, and other styles

28

Lauritano, Dorina, Giulia Moreo, Luisa Limongelli, Elena Tregambi, Annalisa Palmieri, and Francesco Carinci. "Drug-Induced Gingival Overgrowth: A Pilot Study on the Effect of Diphenylhydantoin and Gabapentin on Human Gingival Fibroblasts." International Journal of Environmental Research and Public Health 17, no. 21 (2020): 8229. http://dx.doi.org/10.3390/ijerph17218229.

Full text

Abstract:

Introduction. The administration of several classes of drugs can lead to the onset of gingival overgrowth: anticonvulsants, immunosuppressants, and calcium channel blockers. Among the anticonvulsants, the main drug associated with gingival overgrowth is diphenylhydantoin. Materials and Methods. In this study, we compared the effects of diphenylhydantoin and gabapentin on 57 genes belonging to the “Extracellular Matrix and Adhesion Molecule” pathway, present in human fibroblasts of healthy volunteers. Results. Both molecules induce the same gene expression profile in fibroblasts as well as a si

APA, Harvard, Vancouver, ISO, and other styles

29

Kotepui, Manas, Charin Thawornkuno, Porntip Chavalitshewinkoon-Petmitr, Phaibul Punyarit, and Songsak Petmitr. "Quantitative Real-Time RT-PCR of ITGA7, SVEP1, TNS1, LPHN3, SEMA3G, KLB and MMP13 mRNA Expression in Breast Cancer." Asian Pacific Journal of Cancer Prevention 13, no. 11 (2012): 5879–82. http://dx.doi.org/10.7314/apjcp.2012.13.11.5879.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Vignier, Nicolas, Behzad Moghadaszadeh, Françoise Gary, Jacques Beckmann, Ulrike Mayer та Pascale Guicheney. "Structure, Genetic Localization, and Identification of the Cardiac and Skeletal Muscle Transcripts of the Human Integrin α7 Gene (ITGA7)". Biochemical and Biophysical Research Communications 260, № 2 (1999): 357–64. http://dx.doi.org/10.1006/bbrc.1999.0916.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Qiu, H. F., X. W. Xu, S. H. Zhao, B. Fan, M. Yerle, and B. Liu. "Somatic cell hybrid and RH mapping of the porcine LGALS1, ITGA7, ITGB1, LGALS3, NOL12, GGA1, SH3BP1 and PDXP genes." Animal Genetics 38, no. 3 (2007): 315–16. http://dx.doi.org/10.1111/j.1365-2052.2007.01599.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Heller, Kristin N., Chrystal L. Montgomery, Kimberly M. Shontz, K. Reed Clark, Jerry R. Mendell та Louise R. Rodino-Klapac. "Human α7 Integrin Gene (ITGA7) Delivered by Adeno-Associated Virus Extends Survival of Severely Affected Dystrophin/Utrophin-Deficient Mice". Human Gene Therapy 26, № 10 (2015): 647–56. http://dx.doi.org/10.1089/hum.2015.062.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Chu, Tian Jiao, and David G. Peters. "Serial analysis of the vascular endothelial transcriptome under static and shear stress conditions." Physiological Genomics 34, no. 2 (2008): 185–92. http://dx.doi.org/10.1152/physiolgenomics.90201.2008.

Full text

Abstract:

We have utilized serial analysis of gene expression (SAGE) to analyze the response of human coronary artery endothelial cells (HCAECs) to laminar shear stress (LSS). Primary cultures of HCAECs were exposed to 15 dyn/cm2LSS for 24 h in a parallel plate flow chamber and compared with identical same passage cells cultured under static conditions. The expression levels of a number of functional categories of genes were reduced by shear stress including those encoding proteins involved in cell proliferation (CDC10, CDC20, CDC23, CCND1, CCNB1), angiogenesis (ANGPTL4, CTGF, CYR61, ENG, EPAS1, EGFR, L

APA, Harvard, Vancouver, ISO, and other styles

34

Shi, Dianchun, Zhong Zhong, Ricong Xu, et al. "Association of ITGAX and ITGAM gene polymorphisms with susceptibility to IgA nephropathy." Journal of Human Genetics 64, no. 9 (2019): 927–35. http://dx.doi.org/10.1038/s10038-019-0632-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Dardiotis, Efthimios, Elena Panayiotou, Vasileios Siokas, et al. "Gene variants of adhesion molecules predispose to MS: A case-control study." Neurology Genetics 5, no. 1 (2019): e304. http://dx.doi.org/10.1212/nxg.0000000000000304.

Full text

Abstract:

ObjectiveTo examine the effect of variants in genes encoding molecules that are implicated in leukocyte trafficking into the CNS on the development of MS.MethodsA total of 389 Greek MS cases and 336 controls were recruited by 3 MS centers in Cyprus and Greece. In total, 147 tagging single nucleotide polymorphisms across 9 genes encoding for P-selectin (SELP), integrins (ITGA4, ITGB1, and ITGB7), adhesion molecules (ICAM1, VCAM1, and MADCAM1), fibronectin 1 (FN1), and osteopontin (SPP1) were genotyped. The clinical end point of the study was diagnosis of MS according to the 2005 revised McDonal

APA, Harvard, Vancouver, ISO, and other styles

36

Cheli, Yann, Sachiko Kanaji, Beatrice Jacquelin, Mei Chang, Diane J. Nugent, and Thomas J. Kunicki. "Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2." Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1769, no. 9-10 (2007): 546–58. http://dx.doi.org/10.1016/j.bbaexp.2007.06.004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Konstantinovsky, Sophya, Yoav Smith, Sofia Zilber, et al. "Breast Carcinoma Cells in Primary Tumors and Effusions Have Different Gene Array Profiles." Journal of Oncology 2010 (2010): 1–14. http://dx.doi.org/10.1155/2010/969084.

Full text

Abstract:

The detection of breast carcinoma cells in effusions is associated with rapidly fatal outcome, but these cells are poorly characterized at the molecular level. This study compared the gene array signatures of breast carcinoma cells in primary carcinomas and effusions. The genetic signature of 10 primary tumors and 10 effusions was analyzed using the Array-Ready Oligo set for the Human Genome platform. Results for selected genes were validated using PCR, Western blotting, and immunohistochemistry. Array analysis identified 255 significantly downregulated and 96 upregulated genes in the effusion

APA, Harvard, Vancouver, ISO, and other styles

38

Geng, Xin, Marguerite R. Irvin, Bertha Hidalgo, et al. "An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort." Journal of Lipid Research 59, no. 4 (2018): 722–29. http://dx.doi.org/10.1194/jlr.p080333.

Full text

Abstract:

Our understanding of genetic influences on the response of lipids to specific interventions is limited. In this study, we sought to elucidate effects of rare genetic variants on lipid response to a high-fat meal challenge and fenofibrate (FFB) therapy in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) cohort using an exome-wide sequencing-based association study. Our results showed that the rare coding variants in ITGA7, SIPA1L2, and CEP72 are significantly associated with fasting LDL cholesterol response to FFB (P = 1.24E-07), triglyceride postprandial area under the increase (A

APA, Harvard, Vancouver, ISO, and other styles

39

Wang, Jun-Fu, Ye Wang, Si-Wen Zhang, et al. "Expression and Prognostic Analysis of Integrins in Gastric Cancer." Journal of Oncology 2020 (November 30, 2020): 1–19. http://dx.doi.org/10.1155/2020/8862228.

Full text

Abstract:

Background. Integrins are involved in the biological process of a variety of cancers, but their importance in the diagnosis and prognosis of gastric cancer (GC) is still unclear. Therefore, this study aimed at exploring the significance of ITG gene expression in GC to evaluate its diagnosis and prognosis. Methods. GEPIA data were used to evaluate the mRNA expression of ITG genes in GC patients. The prognostic value of these genes was assessed by analyzing their mRNA expression using the Kaplan–Meier curve. The biological function of ITG genes was evaluated by GC tissue sequencing combined with

APA, Harvard, Vancouver, ISO, and other styles

40

Wang, Weigwang, Wei Wu, Trushna Desai, David C. Ward та Stephen J. Kaufman. "Localization of the α7 integrin gene (ITGA7) on human chromosome 12q13: clustering of integrin and hox genes implies parallel evolution of these gene families". Genomics 26, № 3 (1995): 563–70. http://dx.doi.org/10.1016/0888-7543(95)80176-m.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Leyretana, Maia Isabella R., Marie Angeline M. Francisco, Kevin Benedict O. Cristobal, Andre Rhey C. Haro, Kim Ivan A. Abesamis, and Neil Andrew D. Bascos. "In Silico and In Vitro Analysis of ITGB1 Binding to its Partners ITGA5 and ITGA6." Biophysical Journal 114, no. 3 (2018): 425a—426a. http://dx.doi.org/10.1016/j.bpj.2017.11.2358.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Mohamed, Aminetou Mint, Morgan Thenoz, Catherine Koering, et al. "DEK and WT1 Affect Alternative Splicing of Genes Involved in Hematopoietic Cell Lineage and Resistance to Chemotherapy in Acute Myeloid Leukemia Cells." Blood 120, no. 21 (2012): 2392. http://dx.doi.org/10.1182/blood.v120.21.2392.2392.

Full text

Abstract:

Abstract Abstract 2392 In humans, the majority of all protein-coding transcripts contain introns that are removed by mRNA splicing carried out by spliceosomes. Mutations in the spliceosome machinery have recently been identified using whole-exome/genome technologies in myelodysplastic syndromes (MDS) and in acute myeloid leukemia (AML). In MDS the frequency of somatic spliceosomal mutations (SSM) range from 1–3% for U2AF1 in RARS/RCMD-RS to more than 70% for SF3B1 in ARSI. These values are significantly lower in AML whereas AML cells cumulate numerous splicing defects. Beside SSMs, one can pro

APA, Harvard, Vancouver, ISO, and other styles

43

Kareddula, Aparna, Daniel J. Medina, Whitney Petrosky, et al. "The role of chromodomain helicase DNA binding protein 1 (CHD1) in promoting an invasive prostate cancer phenotype." Therapeutic Advances in Urology 13 (January 2021): 175628722110224. http://dx.doi.org/10.1177/17562872211022462.

Full text

Abstract:

Background: Prostate cancer (PCa) phenotypes vary from indolent to aggressive. Molecular subtyping may be useful in predicting aggressive cancers and directing therapy. One such subtype involving deletions of chromodomain helicase DNA binding protein 1 ( CHD1), a tumor suppressor gene, are found in 10–26% of PCa tumors. In this study, we evaluate the functional cellular effects that follow CHD1 deletion. Methods: CHD1 was knocked out (KO) in the non-tumorigenic, human papillomavirus 16 (HPV16)-immortalized prostate epithelial cell line, RWPE-1, using CRISPR/Cas9. In vitro assays such as T7 end

APA, Harvard, Vancouver, ISO, and other styles

44

Dardiotis, Efthimios, Elena Panayiotou, Antonios Provatas, et al. "Gene variants of adhesion molecules act as modifiers of disease severity in MS." Neurology - Neuroimmunology Neuroinflammation 4, no. 4 (2017): e350. http://dx.doi.org/10.1212/nxi.0000000000000350.

Full text

Abstract:

Objective:To assess the potential effect of variants in genes encoding molecules that are implicated in leukocyte trafficking into the CNS on the clinical phenotype of multiple sclerosis (MS).Methods:A total of 389 Greek MS cases and 336 controls were recruited in 3 MS centers from Cyprus and Greece. We genotyped 147 tagging single nucleotide polymorphisms (SNPs) in 9 genes encoding for P-selectin (SELP), integrins (ITGA4, ITGB1, and ITGB7), adhesion molecules (ICAM1, VCAM1, and MADCAM1), fibronectin 1 (FN1), and osteopontin (SPP1) involved in lymphocyte adhesion and trafficking into the CNS.

APA, Harvard, Vancouver, ISO, and other styles

45

Zainullina, O. N., D. V. Pechkurov, Z. R. Khismatullina, K. Yu Dushina, and L. V. Gankovskaya. "Study of the level of integrins ITGA4 and ITGB7 in blood serum in children with atopic dermatitis." Klinicheskaya dermatologiya i venerologiya 19, no. 6 (2020): 817. http://dx.doi.org/10.17116/klinderma202019061817.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

EM, Morandi, Verstappen R, Zwierzina ME, Geley S, Pierer G, and Ploner C. "Abstract 13.45 ITGAV AND ITGA5 DIVERSELY REGULATE PROLIFERATION AND ADIPOGENIC DIFFERENTIATION OF HUMAN ADIPOSE DERIVED STEM CELLS." Plastic and Reconstructive Surgery - Global Open 6 (June 2018): 8. http://dx.doi.org/10.1097/01.gox.0000544052.36687.a2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Szpirer, Claude, Mich�le Rivi�re, Josiane Szpirer, et al. "Assignment of three rat integrin genes to Chromosome 19 (ITGB1), Chromosome 3 (ITGA4), and Chromosome 7 (ITGA5)." Mammalian Genome 3, no. 12 (1992): 685–88. http://dx.doi.org/10.1007/bf00444363.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Zainullina, O. N., D. V. Pechkurov, Z. R. Khismatullina, K. Yu Dushina, and L. V. Gankovskaya. "Study of the level of integrins ITGA4 and ITGB7 in blood serum in children with atopic dermatitis." Klinicheskaya dermatologiya i venerologiya 19, no. 6 (2020): 817. http://dx.doi.org/10.17116/klinderma202019061817.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Al Amri, Waleed S., Diana E. Baxter, Andrew M. Hanby, et al. "Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants." Breast Cancer Research and Treatment 183, no. 3 (2020): 607–16. http://dx.doi.org/10.1007/s10549-020-05836-7.

Full text

Abstract:

Abstract Purpose More than a third of primary breast cancer patients are treated with cytotoxic chemotherapy, typically without guidance from predictive markers. Increased use of neoadjuvant chemotherapy provides opportunities for identification of molecules associated with treatment response, by comparing matched tumour samples before and after therapy. Our hypothesis was that somatic variants of increased prevalence after therapy promote resistance, while variants with reduced prevalence cause sensitivity. Methods We performed systematic analyses of matched pairs of cancer exomes from primar

APA, Harvard, Vancouver, ISO, and other styles

50

Mostafavi-Pour, Zohreh, Mohammad Reza Ashrafi, and Tahereh Talaei-Khozani. "Down regulation of ITGA4 and ITGA5 genes after formation of 3D spherules by human Wharton’s jelly stem cells (hWJSCs)." Molecular Biology Reports 45, no. 3 (2018): 245–52. http://dx.doi.org/10.1007/s11033-018-4157-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!