Academic literature on the topic 'Its natural product and pharmaceutics'

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Journal articles on the topic "Its natural product and pharmaceutics"

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Atiur, Ahmed. "A review on recent advances in the synthesis of indole and its analogs via C-H activation as a key step." Journal of Indian Chemical Society Vol. 97, No. 9b, Sept 2020 (2020): 1426–41. https://doi.org/10.5281/zenodo.5656702.

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Memari College, Memari, Purba Bardhaman-713 146, West Bengal, India <em>E-mail: </em>atiur.chem@gmail.com <em>Manuscript received online 09 July 2020, accepted 28 August 2020</em> Indole is widely found as the building block in various pharmaceuticals, natural products, agrochemicals, dyes and fragrances. Thus chemists were attracted in developing new methods to prepare this moiety. Over the years, various strategies including C-H activation have been employed to afford these heterocycles. Therefore the continuous updates of the new approaches developed are essential. In this review, significa
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Dias, Lucas D., Fernanda Mansano Carbinatto, Isabelle da Silveira Almeida, et al. "Eco-Friendly Extraction of Green Coffee Oil for Industrial Applications: Its Antioxidant, Cytotoxic, Clonogenic, and Wound Healing Properties." Fermentation 9, no. 4 (2023): 370. http://dx.doi.org/10.3390/fermentation9040370.

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The development of natural oil-based cosmetic and pharmaceutical products presents great scientific and commercial interest. Herein, we aimed to extract green coffee oil from Arabic coffee by a sustainable cold-pressing method. Furthermore, this work aimed to characterize the obtained green coffee oil by Fourier-Transform Infrared (FT–IR) and ultraviolet–visible spectroscopies (UV–Vis), peroxide analysis, and fatty acids profile by gas chromatography–mass spectrometry (GC–MS). Moreover, the functional and biological properties of the obtained green coffee oil and a green-coffee oil-based comme
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Ramezani, Moazzameh, Melika Hasani, Fatemeh Ramezani, and Mahmood Karimi Abdolmaleki. "Cucurbitacins: A Focus on Cucurbitacin E As A Natural Product and Their Biological Activities." Pharmaceutical Sciences 27, no. 1 (2020): 1–13. http://dx.doi.org/10.34172/ps.2020.66.

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For the last years, different types of cucurbitacins have been extracted from various species of Cucurbitaceae family. For this review, all related papers were accumulated by searching electronic databases in the English language, including PubMed, Scopus, and Google Scholar. The keywords of cucurbitacin, cucumber anticancer therapy, cytotoxic effects, chemotherapy, and inhibitor effect were searched until February 2020. According to the result of this review, cucurbitacin E as a tetracyclic triterpenes compound, has been exhibited cell cycle arrest, anti-inflammatory and anticancer activities
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Zhu, Saibin, Yanwen Duan, and Yong Huang. "The Application of Ribosome Engineering to Natural Product Discovery and Yield Improvement in Streptomyces." Antibiotics 8, no. 3 (2019): 133. http://dx.doi.org/10.3390/antibiotics8030133.

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Microbial natural product drug discovery and development has entered a new era, driven by microbial genomics and synthetic biology. Genome sequencing has revealed the vast potential to produce valuable secondary metabolites in bacteria and fungi. However, many of the biosynthetic gene clusters are silent under standard fermentation conditions. By rational screening for mutations in bacterial ribosomal proteins or RNA polymerases, ribosome engineering is a versatile approach to obtain mutants with improved titers for microbial product formation or new natural products through activating silent
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Rosales Martínez, Antonio, Ignacio Rodríguez-García, and Josefa L. López-Martínez. "Divergent Strategy in Marine Tetracyclic Meroterpenoids Synthesis." Marine Drugs 19, no. 5 (2021): 273. http://dx.doi.org/10.3390/md19050273.

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The divergent total synthesis strategy can be successfully applied to the preparation of families of natural products using a common late-stage pluripotent intermediate. This approach is a powerful tool in organic synthesis as it offers opportunities for the efficient preparation of structurally related compounds. This article reviews the synthesis of the marine natural product aureol, as well as its use as a common intermediate in the divergent synthesis of other marine natural and non-natural tetracyclic meroterpenoids.
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Pereira, Ricardo F. S., and Carla C. C. R. de Carvalho. "Improving Bioprocess Conditions for the Production of Prodigiosin Using a Marine Serratia rubidaea Strain." Marine Drugs 22, no. 4 (2024): 142. http://dx.doi.org/10.3390/md22040142.

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The enormous potential attributed to prodigiosin regarding its applicability as a natural pigment and pharmaceutical agent justifies the development of sound bioprocesses for its production. Using a Serratia rubidaea strain isolated from a shallow-water hydrothermal vent, optimization of the growth medium composition was carried out. After medium development, the bacterium temperature, light and oxygen needs were studied, as was growth inhibition by product concentration. The implemented changes led to a 13-fold increase in prodigiosin production in a shake flask, reaching 19.7 mg/L. The condi
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Sun, Xueni, Yintao Zhang, Ying Zhou, et al. "NPCDR: natural product-based drug combination and its disease-specific molecular regulation." Nucleic Acids Research 50, no. D1 (2021): D1324—D1333. http://dx.doi.org/10.1093/nar/gkab913.

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Abstract Natural product (NP) has a long history in promoting modern drug discovery, which has derived or inspired a large number of currently prescribed drugs. Recently, the NPs have emerged as the ideal candidates to combine with other therapeutic strategies to deal with the persistent challenge of conventional therapy, and the molecular regulation mechanism underlying these combinations is crucial for the related communities. Thus, it is urgently demanded to comprehensively provide the disease-specific molecular regulation data for various NP-based drug combinations. However, no database ha
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Čanji-Panić, Jelena, Nemanja Todorović, Ana Stjepanović, and Mladena Lalić-Popović. "The potential of natural products use in fused deposition modeling 3D printing of pharmaceutical dosage forms." Arhiv za farmaciju 72, no. 6 (2022): 621–36. http://dx.doi.org/10.5937/arhfarm72-40155.

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In recent years, the interest in 3D printing of medicines has increased due to many advantages of this technology, such as flexibility of the dose and dosage form of the printed product. Fused deposition modeling (FDM) is one of the most popular 3D printing technologies in the pharmaceutical field, due to its low cost and simplicity. The subject of this review is the potential use of natural products as biodegradable and biocompatible materials with good safety profiles in FDM 3D printing of pharmaceuticals. Natural products such as alginate, chitosan and starch have already been employed as e
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Debnath, Pradip. "Recent Advances in the Hofmann Rearrangement and Its Application to Natural Product Synthesis." Current Organic Chemistry 23, no. 22 (2020): 2402–35. http://dx.doi.org/10.2174/1385272823666191021115508.

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: C-N bond formation reactions are the most important transformations in (bio)organic chemistry because of the widespread occurrence of amines in pharmaceuticals, natural products, and biologically active compounds. The Hofmann rearrangement is a well-known method used for the preparation of primary amines from amides. But, the traditional version of the Hofmann rearrangement often gave relatively poor yields due to over-oxidation or due to the poor solubility of some amides in aqueous base, and created an enormous amount of waste products. Developments over the last two decades, in particular
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Krings, Ulrich, and Ralf Guenter Berger. "Terpene Bioconversion – How does its Future Look?" Natural Product Communications 5, no. 9 (2010): 1934578X1000500. http://dx.doi.org/10.1177/1934578x1000500927.

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The usage of essential oils as such or of volatile fractions thereof is widespread in the flavor and fragrance industry to aromatize perfumery and cosmetic products, foodstuffs, and many household and pharmaceutical products. The increased market share of convenience food together with consumers’ request for constant high quality and natural products have established a lasting increase in the demand for natural flavorings that cannot be satisfied by the traditional plant materials. This review summarizes selected work on terpene bioconversion / transformation and focuses on recently published
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Dissertations / Theses on the topic "Its natural product and pharmaceutics"

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Fang, Chao. "Synthetic Studies Toward Marine Natural Product Okadaic Acid and Its Analogs." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1306336570.

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Saunders-Mattingly, Meredith A. "DISCOVERY OF NATURAL PRODUCT ANALOGS AGAINST ETHANOL-INDUCED CYTOTOXICITY IN HIPPOCAMPAL SLICE CULTURES." UKnowledge, 2018. https://uknowledge.uky.edu/psychology_etds/142.

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An estimated 13.9% of Americans currently meet criteria for an alcohol (ethanol; EtOH) use disorder (AUD). While there are 4 medications approved by the Food and Drug Administration (FDA) to treat AUD, these treatments have demonstrated poor clinical efficacy. Our ongoing research program encompasses a multi-tiered screening of a natural product library and validation process to provide novel information about the mechanisms underlying EtOH-induced changes in neurobiology and to identify novel chemical scaffolds to be exploited in the development of pharmacological treatments for AUD in a rode
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Lavallée, Vincent Paul. "Antipain and its analogues, natural product inhibitors of cathepsin K isolated from streptomyces." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/33846.

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In human bone, 90% of organic bone matrix is composed of type 1 collagen. Cathepsin K is a cysteine protease involved in osteoclast mediated bone absorption and has been identified as a major drug target for the treatment of osteoporosis. Numerous potent inhibitors of cathepsin K have already been identified from natural sources including epoxide inhibitors such as E-64 isolated from the fungi Aspergillus japonicus as well as various peptide aldehydes such as Leupeptin and alpha-MAPI purified from Streptomyces. 350 soil and lichen-associated bacterial strains collected in the rain forests of B
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Ralston, Kevin John. "Studies towards the total synthesis of disorazole C1 and its analogues." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/9954.

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Structure-activity relationships (SARs) in the disorazole family have been revealed through the biological testing of natural disorazoles and their synthetic analogues, but little is known about the contribution of the oxazole to the anti-tubulin activity of disorazole C1 I. The development of a novel Evans-Tishchenko/alkyne metathesis (ET-AM) route towards the synthesis of disorazole C1 will provide straightforward access to disorazole C1 and its heterocyclic analogues, thus allowing the contribution of the oxazole to the natural product's bioactivity to be elucidated. Our ET-AM approach offe
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Yang, Fan. "Chemotaxonomy Study of Plants from the Family Proteaceae Based on Its Natural Product Profile (Alkaloid)." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/367627.

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The Proteaceae is a flowering plant family containing approximately 1700 species across more than 80 genera and is a predominant feature of Australian and South African flora. The chemistry of plants from the family has been studied by researchers for over a century but these studies have neither been systematic nor extensive. The research carried out in this thesis has firstly systematically reviewed and synthesized the current state of knowledge with regard to the natural products chemistry of the Proteaceae in relation to taxonomic groupings derived from molecular and morphometric phylogene
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Das, Anushree. "Photogeneration Mechanism of Reactive Intermediate and its Applications in Photoremovable Protecting Group and Natural Product Synthesis." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1479814832756981.

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Kumarn, Sirirat. "A highly selective organocatalytic route to chiral 1,2-oxazines and 3,6-dihydropyridazines and its application in natural product synthesis." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612392.

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Cheng, Jiye. "Development of a Metabolomics Strategy for Novel Natural Product Discovery and its Application to the Study of Soybean Defense Responses." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1307389510.

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Napan, Kandy L. "Investigation of the Tailoring Steps in Pradimicin Biosynthesis." DigitalCommons@USU, 2016. https://digitalcommons.usu.edu/etd/4730.

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The actinobacteria Actinomadura hibisca synthesizes the natural products pradimicin A-C through a type II polyketide biosynthetic pathway. Eight tailoring enzymes in pradimicin biosynthesis have been investigated in this work, including PdmJ, PdmW, PdmN, PdmT, PdmO, PdmS, PdmQ and PdmF. PdmJ and PdmW were characterized as cytochrome P450 hydroxylases that catalyze the incorporation of two hydroxyl groups at C-5 and C-6, respectively. These enzymes worked synergistically and their co-expression significantly improved the efficiency of the hydroxylation steps. PdmN is an amino acid ligase that a
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Lehner, Verena [Verfasser], and Oliver [Akademischer Betreuer] Reiser. "Rh(II)-catalyzed Cyclopropanation of Aromatic Heterocycles and its Application to the Total Synthesis of Natural Product Derivatives / Verena Lehner ; Betreuer: Oliver Reiser." Regensburg : Universitätsbibliothek Regensburg, 2017. http://d-nb.info/1168903033/34.

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Books on the topic "Its natural product and pharmaceutics"

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Ayres, Robert U. The life cycle of copper, its co-products and byproducts. Kluwer Academic, 2003.

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Ayres, Robert U. The life cycle of copper, its co-products and byproducts. Kluwer Academic, 2003.

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Vairappan, Charles S. Ecological Chemicals as Ecosystem Function Mediaters and Potential Lead Pharmaceuticals. UMS Press, 2021. http://dx.doi.org/10.51200/ecologicalchemicalsumspress2021-978-967-2962-94-6.

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Relationship between functioning ecosystem services and human wellbeing has been established as a bridge connecting nature and society. It has also become central pillar of sustainability science and dictates the paradigms of sustainable development. But, conceptual frameworks that systematically integrates the important roles played by natural ecological chemicals by establishing empirical links between the nature and ecology not only varies, but lacks clear support. The value of ecological chemicals as ecosystem derived natural products warrants explicit acknowledgement, only then trade-offs
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Ayres, Leslie W., Ingrid Råde, and Robert U. Ayres. Life Cycle of Copper, Its Co-Products and Byproducts. Springer, 2013.

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Ayres, Leslie W., Ingrid Råde, and Robert U. Ayres. Life Cycle of Copper, Its Co-Products and Byproducts. Springer Netherlands, 2010.

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Li, Jie Jack. Blockbuster Drugs. Oxford University Press, 2014. http://dx.doi.org/10.1093/oso/9780199737680.001.0001.

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For the world's largest prescription drug manufacturers, the last few years have been a harrowing time. Recently, Pfizer's Lipitor, GlaxoSmithKline's Advair, AstraZeneca's Seroquel, and Sanofi-Aventis and Bristol-Myers Squibb's Plavix all came off patent in the crucial U.S. market. This so-called "patent cliff" meant hundreds of billions of dollars in lost revenue and has pharmaceutical developers scrambling to create new drugs and litigating to extend current patent protections. Having spent most of his career in drug discovery in "big pharma," Dr. Li now delivers an insider's account of how
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Ayres, Robert U., Leslie W. Ayres, and Ingrid Råde. The Life Cycle of Copper, Its Co-Products and Byproducts (Eco-Efficiency in Industry and Science). Springer, 2007.

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Kayat, Kalsom. Homestay programme as a Malaysian tourism product. UUM press, 2011. http://dx.doi.org/10.32890/9789675311673.

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This book discusses the homestay programme in Malaysia in the context of tourism product.It begins by looking into the evolution of tourism in Malaysia, focusing on its growth and development.Tourism product is an important component of any tourism destination, thus the book later looks into the product concept as well as the development of tourism products in Malaysia.Malaysia has many natural, cultural and man-made tourist products and attractions that can potentially pull tourists to its shore.The rest of the book then turns into the discussion of the Malaysian homestay programme.The progra
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Hall, Kersten T. Insulin - The Crooked Timber. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780192855381.001.0001.

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Before the discovery of insulin, a diagnosis of type 1 diabetes was an inevitable death sentence. Little wonder then that when insulin was first used to treat patients in the early 1920s, diabetes specialist Elliott Joslin likened its power to the ‘Vision of Ezekiel’, the Old Testament prophet who is said to have seen a valley of dry bones rise up and be restored to life. Despite its life-saving power, however, little was known about the chemical nature of insulin, with one clinician describing it as being simply ‘thick brown muck’. Just over half a century later, insulin was again causing exc
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Carlos Maria, Correa. Trade Related Aspects of Intellectual Property Rights. Oxford University Press, 2020. http://dx.doi.org/10.1093/law/9780198707219.001.0001.

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The Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) is the most comprehensive and influential international treaty on intellectual property rights. It brings intellectual property rules into the framework of the World Trade Organization, obliging all WTO Member States to meet minimum standards of intellectual property protection and enforcement. This has required massive changes in some national laws, particularly in developing countries. This book provides an in-depth analysis of the principles and of the substantive and enforcement provisions of the TRIPS Agreement
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Book chapters on the topic "Its natural product and pharmaceutics"

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Nath, Rajat, Anupam Das Talukdar, Priyanka Saha, et al. "Intellectual Property Rights and Its Role in Natural Product Research." In Advances in Pharmaceutical Biotechnology. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-2195-9_29.

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Agrawal, Mohit, Yash Jasoria, Hema Chaudhary, Bhupendra Prajapati, and Md Faiyazuddin. "Marine Natural Product Database for Exploring New Drugs." In Handbook of Research in Marine Pharmaceutics. Apple Academic Press, 2024. http://dx.doi.org/10.1201/9781003537403-2.

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Knight, David W. "Oxazole and Its Derivatives." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch12.

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Yoda, Hidemi, Masaki Takahashi, and Tetsuya Sengoku. "Azetidine and Its Derivatives." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch2.

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Boto, Alicia, and Laura Alvarez. "Furan and Its Derivatives." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch4.

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Miyabe, Hideto, Okiko Miyata, and Takeaki Naito. "Pyran and Its Derivatives." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch5.

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Mal, Dipakranjan, Brateen Shome, and Bidyut Kumar Dinda. "Pyrrole and Its Derivatives." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch6.

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Kiuru, Paula, and Jari Yli-Kauhaluoma. "Pyridine and Its Derivatives." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch8.

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Naqvi, Sabira, H. Jornvall, and Z. H. Zaidi. "Primary Structure of Hemoglobin from Reptile Uromastix hardwickii and its Status in Molecular Evolution." In Natural Product Chemistry. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71425-2_27.

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Ahmad, Yusuf. "Hypcholesterolemic Effect of Allium sativum Linn. and its Potential Protective Action Against Coronary Heart Disease." In Natural Product Chemistry. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71425-2_2.

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Conference papers on the topic "Its natural product and pharmaceutics"

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Jancy, Howard. "Coloring Stains for Concrete." In Paint and Coatings Expo (PACE) 2009. SSPC, 2009. https://doi.org/10.5006/s2009-00021.

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Abstract Concrete is an inherently attractive building material. It expresses the natural appeal of stone by its mass and permanence. With the addition of natural looking color variations, concrete as stone, is even more realistic. Concrete stains are an excellent choice for producing colors often found in earth and rock. When combined with simple and creative application techniques, stains allow for truly unique concrete installations, which complement a variety of hardscape and flooring designs. Stains are also quite useful for finishes that are more contemporary. Concrete floors, countertop
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Tuthill, Arthur H. "Usage and Performance of Nickel Stainless Steels in Natural Waters and Brines." In CORROSION 1988. NACE International, 1988. https://doi.org/10.5006/c1988-88408.

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Abstract Actual performance of various grades of stainless steels in saline waters in 80 coastal industrial plants as reported in interviews with cognizant materials personnel and as documented in the author's files is summarized by alloy or alloy group and by product form.(l) User supplied information of this type is by its nature incomplete and not as precise as data developed under controlled conditions in the laboratory. Nevertheless, it does provide good insight into overall alloy performance and overall patterns of alloy usage.
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Srinivasan, Sridhar, and Gerrit Buchheim. "High Temperature Corrosion Quantification in Renewable Diesel and Sustainable Aviation Fuel Applications." In MECC 2023. AMPP, 2023. https://doi.org/10.5006/mecc2023-20056.

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Abstract Production of Renewable Diesel (RD) and Sustainable Aviation Fuels (SAF) from biological sources (natural oils) has seen exponential growth in recent years, stemming from worldwide government mandated climate change initiatives alongside the need for carbon capture and sequestration. Significant, rapid investments have occurred in retrofitting / adapting existing refinery hydroprocessing infrastructure to process natural oils or coprocess natural oils blended with crudes to produce RD and SAF. This stems from the fact that natural oils have the hydrocarbon (HC) structures to fit withi
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Srinivasan, Sridhar, Winston Robbins, and Gerrit Buchheim. "Quantifying High Temperature Corrosion in Renewable Diesel and Sustainable Aviation Fuel Production." In CONFERENCE 2023. AMPP, 2023. https://doi.org/10.5006/c2023-19457.

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Abstract Production of Renewable Diesel (RD) and Sustainable Aviation Fuels (SAF) from bio / natural oils has seen tremendous interest and investment in recent years, stemming from worldwide government mandated need to reduce fossil fuel CO2 emissions. Significant, rapid investments have occurred in retrofitting / adapting existing refinery hydroprocessing infrastructure to process natural oils or coprocess natural oils blended with crudes to produce RD and SAF. This stems from the fact that natural oils have the hydrocarbon (HC) structures to fit within the mid-distillate fuel product such as
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Wang, W., and W. H. Hartt. "A Novel Approach to Polarization Data Analysis and Its Implications regarding Cathodic Protection System Design and Performance." In CORROSION 1994. NACE International, 1994. https://doi.org/10.5006/c1994-94496.

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Abstract Experiments were performed whereby steel cathodes were cathodically polarized in natural sea water by galvanic coupling to an aluminum anode through an external resistor. The change in potential versus current density data with time was found to be linear with a slope equal to the product of the total circuit resistance and cathode surface area and with the vertical intercept corresponding to the anode corrosion potential. Based upon the data from these experiments and comparison with survey results from an instrumented offshore structure, it is projected that the potential-current de
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Shaikhah, Dilshad, Bruce Cowe, Wassim Taleb, Anne Neville, Maalek Mohamed-Said, and Richard Barker. "In-situ Synthesis of Corrosion Product-polymer Composites on Carbon Steel for Enhanced Erosion-corrosion Protection in CO2 Corrosion Environments." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17717.

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Abstract Iron carbonate (FeCO3) is a common corrosion product found on steel surfaces in carbon dioxide (CO2)-containing aqueous environments. The formation of this corrosion product on the internal walls of carbon steel pipelines can suppress material dissolution by over an order of magnitude, providing an effective form of corrosion inhibition. One significant limitation associated with relying upon solely FeCO3 to suppress material dissolution is its propensity to be locally removed by chemical or mechanical mechanisms. Here we report a novel strategy, implemented to generate a mineral-poly
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Svetlik, Harvey. "High Performance Pipeline Polyethylene Liner in Hostile Environments." In CORROSION 1987. NACE International, 1987. https://doi.org/10.5006/c1987-87243.

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Abstract Each year, the U. S. Department of Transportation issues in July its "Annual Report on Pipeline Safety." That report incorporates information covered by the Natural Gas Pipeline Safety Act and the Hazardous Liquid Pipeline Safety Act. Included in that report are interesting summaries such as the two taken from the 1984 report. Table 1 and Table 2 list the number and cause of actual gas pipeline failures. Table 3 lists the liquid pipeline failures by cause and by product. Pipeline internal corrosion accounts for a noticeable percentage of pipeline leaks. In 1984, liquid pipeline intern
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Grinco, Marina, Alexandru Marina, Natalia Birca, et al. "Pomolic acid from apple pomace: quantitative determination by heteronuclear two-dimentional QNMR and preparative isolation." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab14.

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Pomolic acid (PA) is a pentacyclic triterpenic acid isolated from apples by Brieskorn and Wunderer in 1967 [1]. Its highly relevant biological activity profile came recently into focus and there have been many reports on the content of PA in different plant sources [2]. Quite surprisingly, the general perception of low PA content in plants persists and this information hinders its broader investigation as a compound of pharmaceutical and nutraceutical potential. The main aim of the current work was quantitative determination of pomolic acid in apple pomace by two-dimensional heteronuclear NMR
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Cojocaru-Toma, Maria, Vladimir Valica, Vladilena Gandacov, Ecaterina Mazur, and Livia Uncu. "Phenolic compounds in Agrimonia eupatoria l. Ethanolic extract evaluated by HPLC." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab17.

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Agrimonia eupatoria L. (Rosaceae fam.) is widespread in temperate regions. In folk medicine, this species has been used for its astringent, analgesic and anti-inflammatory, as well as in gastrointestinal disorders. As these biological properties have been linked to its phenolic composition, this plant species could be an interesting source of bioactive compounds with therapeutic potential [1]. For the evaluation of chemical compounds in A. eupatoria extract, the aerial parts were harvested in the flowering period from the collection of the Scientific Practical Centre in the Field of Medicinal
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Vehar, G. A. "THE PRESENT STATE OF GENE TECHNOLOGY IN THE MANUFACTURE OF HUMAN COAGULATION PROTEINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644755.

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The production of pharmaceuticals from human plasma that are useful in the treatment of bleeding disorders had its beginning with the development of the Cohn fractionation procedure in the 1940's. As a result of these advances, concentrates became available for the treatment of the hemophilias. Although of low purity and subject to contamination by hepatitis virus, the availability of these compounds resulted in dramatic improvements in the life expectancy and quality of life of afflicted individuals. The numerous problems associated with production of pharmaceuticals from pooled plasma made t
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Reports on the topic "Its natural product and pharmaceutics"

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Ruiz de Gauna, Itziar, Anil Markandya, Laura Onofri, et al. Economic Valuation of the Ecosystem Services of the Mesoamerican Reef, and the Allocation and Distribution of these Values. Inter-American Development Bank, 2021. http://dx.doi.org/10.18235/0003289.

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Coral reefs are one of the most diverse and valuable ecosystems on Earth. The Mesoamerican Reef contains the largest barrier reef in the Western Hemisphere. However, its health is threatened, so there is a need for a management and sustainable conservation. Key to this is knowing the economic value of the ecosystem. “Mainstreaming the value of natural capital into policy decision-making is vital” The value of environmental and natural resources reflects what society is willing to pay for a good or service or to conserve natural resources. Conventional economic approaches tended to view value o
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Jinawath, Supatra. Development of products from Mae Moh flue-gas gypsum. Chulalongkorn University, 1999. https://doi.org/10.58837/chula.res.1999.34.

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The flue-gas desulfurization gypsum (FGD gypsum) from Mae Moh power station is characterized for its physical and chemical properties, precleaned by acid leaching and sedimentation to light coloured powder which is later used, in later used, in comparison with natural gypsum, as raw material for the syntheses of [beta]-hemihydrate, anhydrites and multiphase plasters. Based on the commercial specification, these gypsum plasters are fabricated into product, i.e. gypsum board and projection plaster slurry. With the employment of gypsum technology, the product performance can be engineered to matc
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Phillips, Donald A., Yitzhak Spiegel, and Howard Ferris. Optimizing nematode management by defining natural chemical bases of behavior. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7587234.bard.

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This project was based on the hypothesis that nematodes interacting with plants as either parasites or beneficial saprophytes are attracted to their host by natural products. This concept was supported by numerous observations that parasitic nematodes are attracted to root exudates. Our overall goal was to identify nematode sensory compounds from root exudates and to use that information for reducing nematicide applications. We applied skills of the investigators to achieve three specific objectives: 1) Identify nematode behavioral cues (e.g., attractants or repellents) in root exudates; 2) Id
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Fridman, Eyal, and Eran Pichersky. Tomato Natural Insecticides: Elucidation of the Complex Pathway of Methylketone Biosynthesis. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7696543.bard.

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Plant species synthesize a multitude of specialized compounds 10 help ward off pests. and these in turn may well serve as an alternative to synthetic pesticides to reduce environmental damage and health risks to humans. The general goal of this research was to perform a genetic and biochemical dissection of the natural-insecticides methylketone pathway that is specific to the glandular trichomes of the wild species of tomato, Solanumhabrochaites f. glabratum (accession PI126449). Previous study conducted by us have demonstrated that these compounds are synthesized de novo as a derivate pathway
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Lebel, D. Commission géologique du Canada bilan de l'année (rapport suppplémentaire) : 2021-22. Natural Resources Canada/CMSS/Information Management, 2023. http://dx.doi.org/10.4095/331812.

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This report highlights the GSC's additional contribution to NRCan's core mandated responsibility, Natural Resource Science and Risk Mitigation through Geological Knowledge for Canada's Onshore and Offshore Lands; Geoscience for Sustainable Development; and Geoscience for Keeping Canada Safe, and is a companion product to the annual report Geological Survey of Canada Year in Review: 2021-22. The mission of the GSC is to provide authoritative and cutting-edge geoscience information. This document presents a high-level corporate overview of the GSC and its science programs and activities.
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Lebel, D. Geological Survey of Canada year in review (supplemental report): 2021-22. Natural Resources Canada/CMSS/Information Management, 2023. http://dx.doi.org/10.4095/331811.

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This report highlights the GSC's additional contribution to NRCan's core mandated responsibility, Natural Resource Science and Risk Mitigation through Geological Knowledge for Canada's Onshore and Offshore Lands; Geoscience for Sustainable Development; and Geoscience for Keeping Canada Safe, and is a companion product to the annual report Geological Survey of Canada Year in Review: 2021-22. The mission of the GSC is to provide authoritative and cutting-edge geoscience information. This document presents a high-level corporate overview of the GSC and its science programs and activities.
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Borch, Thomas, Yitzhak Hadar, and Tamara Polubesova. Environmental fate of antiepileptic drugs and their metabolites: Biodegradation, complexation, and photodegradation. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597927.bard.

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Many pharmaceutical compounds are active at very low doses, and a portion of them regularly enters municipal sewage systems and wastewater-treatment plants following use, where they often do not fully degrade. Two such compounds, CBZ and LTG, have been detected in wastewater effluents, surface waters, drinking water, and irrigation water, where they pose a risk to the environment and the food supply. These compounds are expected to interact with organic matter in the environment, but little is known about the effect of such interactions on their environmental fate and transport. The original o
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Banerjee, Onil, Martin Cicowiez, Marcia Macedo, et al. An Amazon Tipping Point: The Economic and Environmental Fallout. Inter-American Development Bank, 2021. http://dx.doi.org/10.18235/0003385.

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The Amazon biome, despite its resilience, is being pushed by unsustainable economic drivers towards an ecological tipping point where restoration to its previous state may no longer possible. This is the result of self-reinforcing interactions between deforestation, climate change and fire. In this paper, we develop scenarios that represent movement towards an Amazon tipping point and strategies to avert one. We assess the economic, natural capital and ecosystem services impacts of these scenarios using the Integrated Economic-Environmental Modeling (IEEM) Platform linked with high resolution
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Peterson, Warren. PR-663-19600-Z01 Develop Guidance for Calculation of HCDP in Pipelines. Pipeline Research Council International, Inc. (PRCI), 2020. http://dx.doi.org/10.55274/r0011659.

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To maintain the integrity and reliability of natural gas transportation systems, system operators ensure that products in transit remain in the gas phase under foreseeable operating conditions. Compliance with pipeline hydrocarbon dew point (HCDP) specifications are demonstrated though in-situ testing or predictive models based on Equations of State (EOS) calculations. Numerical prediction of HCDP is a product of contributing elements, including gas chromatography, calibration gas quality, thermophysical science and the experimental data that underpins equations of state. Some hydrocarbon mixt
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Lichter, Amnon, Gopi K. Podila, and Maria R. Davis. Identification of Genetic Determinants that Facilitate Development of B. cinerea at Low Temperature and its Postharvest Pathogenicity. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7592641.bard.

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Botrytis cinerea is the postharvest pathogen of many agricultural produce with table grapes, strawberries and tomatoes as major targets. The high efficiency with which B. cinerea causes disease on these produce during storage is attributed in part due to its exceptional ability to develop at very low temperature. Our major goal was to understand the genetic determinants which enable it to develop at low temperature. The specific research objectives were: 1. Identify expression pattern of genes in a coldenriched cDNA library. 2. Identify B. cinerea orthologs of cold-induced genes 3. Profile pro
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