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1

Cachola, Gonçalo da Silva Brissos Chimelas. "Dependence of IVIM-DWI estimations on acquisition parameters." Master's thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/10914.

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Dissertação para obtenção do Grau de Mestre em Engenharia Biomédica<br>Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver conditions in the Western world. It is normally associated with health disorders such as obesity, diabetes and hypertriglyceridemia. The gold standard for the diagnosis and staging of NAFLD is liver biopsy, which is highly invasive and is associated with high morbidity and inherent sampling error. Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) is able to distinguish between true molecular diffusion and the pseudo-random mo
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Fournet, Gabrielle. "IVIM : modeling, experimental validation and application to animal models." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS367/document.

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Cette thèse porte sur l’étude de la séquence d’imagerie IRM IVIM (« Intravoxel incoherent motion »). Cette séquence permet l’étude des microvaisseaux sanguins tels que les capillaires, artérioles et veinules. Pour être sensible seulement aux groupes de spins non statiques dans les tissus, des gradients de diffusion sont ajoutés avant et après l’impulsion 180° d’une séquence d’écho de spin. La composante du signal correspondant aux spins qui diffusent dans le tissu peut être séparée de celle des spins en mouvement dans les vaisseaux sanguins qui est appelée signal IVIM. Ces deux composantes son
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Liao, Yen-Peng. "Optimal Model Mapping for Intravoxel Incoherent Motion MRI." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263578.

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4

Lewis, Benjamin C. "Radiotherapy Response Using Intravoxel Incoherent Motion Magnetic Resonance Imaging in Liver Patients Treated with Stereotactic Body Radiotherapy." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5821.

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Magnetic resonance imaging is utilized as an important tool in radiation oncology for delineation of healthy and cancerous tissues, and evaluating the functionality of those tissues, structures, and organs. Currently, the clinical imaging protocol at Virginia Commonwealth University includes anatomical imaging for tissue and structure delineation, and to observe treatment induced changes. Diffusion weighted imaging (DWI) is also acquired for calculation of apparent diffusion coefficient (ADC) values to provide quantitative information on tissue diffusivity and microstructure. However, anatomic
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Flammini, Lucia. "Studio e valutazione delle potenzialità della tecnica IVIM per la caratterizzazione dei carcinomi al seno." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/12202/.

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Il carcinoma mammario rappresenta la forma di neoplasia più diffusa al mondo. Nel 2015 sono stati diagnosticati solo in Italia circa 48.000 nuovi casi di carcinomi della mammella femminile. La diagnosi del carcinoma mammario riveste un’importanza fondamentale in quanto minori sono le sue dimensioni al momento della diagnosi maggiori sono le probabilità di guarigione. Il complesso processo di sviluppo e crescita tumorale vede infatti una latenza di molti anni, durante la quale la malattia non manifesta sintomi che possono indurre il medico a sospettarne l’esistenza. Grazie al contributo delle i
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Pavilla, Aude. "Quantification simultanée de la diffusion et de la perfusion cérébrale en imagerie par résonance magnétique : application au diagnostic de l’accident vasculaire cérébral ischémique." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1B025/document.

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L’accident vasculaire cérébral ischémique (AVCi) représente un véritable enjeu de santé publique avec des taux de mortalité et des coûts de prise en charge élevés. L’établissement d’un diagnostic rapide et précis basé sur les signes cliniques et les résultats de l’imagerie médicale est nécessaire pour la prise de décision thérapeutique (thrombolyse ou plus récemment la thrombectomie mécanique). Conformément aux recommandations actuelles, l’IRM est la modalité d’imagerie de première intention à réaliser pour confirmer la suspicion d’AVCi. La réalisation d’une thrombolyse est notamment guidée pa
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Kamakura, Orson Nobumitsu. "Avaliação comparativa dos efeitos do anlodipino e da pimobendana na insuficiência valvar crônica de mitral em cães." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-09052016-140803/.

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A insuficiência valvar crônica de mitral (IVCM) é a principal cardiopatia de cães, correspondendo a 75-85% dos casos de cardiopatias. É causada pela degeneração mixomatosa da valva mitral (endocardiose de mitral) sendo, então, uma doença degenerativa adquirida e que pode ocasionar a insuficiência cardíaca congestiva (ICC). Pode acometer qualquer raça de cão, mas é mais frequentemente observada nas raças de pequeno porte, dentre as quais, Poodle miniatura, Spitz Alemão, Dachshund, Yorkshire Terrier, Chihuahua e Cavalier King Charles Spaniel. Na endocardiose de mitral, o volume sanguíneo regurgi
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Lambertini, Matilde. "La risonanza magnetica pesata in diffusione per la valutazione delle lesioni mammarie." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/12215/.

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Nella pratica clinica la valutazione del tessuto mammario viene effettuata utilizzando tecniche come la mammografia convenzionale o la risonanza magnetica con mezzo di contrasto. Tuttavia queste tecniche presentano sensibilità e accuratezza limitata e non sempre permettono la differenziazione delle lesioni mammarie. Tra le diverse tecniche diagnostiche di imaging biomedico, la risonanza magnetica, con l’utilizzo delle più recenti metodiche di acquisizione come il diffusion weighted imaging, offre la possibilità di effettuare uno studio sia morfologico sia funzionale dell’organo in esame, senz
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Riceputi, Giulia. "Valutazione funzionale delle lesioni al seno tramite nuovi parametri di perfusione e diffusione dall'imaging in risonanza magnetica." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13207/.

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La tecnica di screening attualmente più diffusa è la mammografia a raggi X, che rappresenta il principale metodo diagnostico in fase precoce di neoplasia maligna alla mammella. Essa ha, però, una sensibilità solamente del 69-90% che può ridursi fino al 48% in caso di parenchima denso. Il principale rischio associato alla mammografia è l’esposizione alle radiazioni: i raggi X, infatti, ionizzano le molecole modificando la composizione dei tessuti incrementando la possibilità di incorrere nel cancro. I pericoli di questa tecnica diagnostica sono stati dimostrati da diverse ricerche indipendenti[
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Psotti, Marco. "Studio e valutazione del contributo della risonanza magnetica pesata in diffusione nei pazienti affetti da malattia policistica renale autosomica dominante." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13943/.

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Nell'elaborato di tesi viene esposto il metodo di imaging tramite risonanza magnetica pesata in diffusione e i modelli matematici ad esso associati, il modello monoesponenziale ADC (Apparent Diffusion Coefficient) e il modello biesponenziale IVIM (IntraVoxel Incoherent Motion). Successivamente viene esposta la fisiopatologia della malattia renale policistica autosomica dominante o ADPKD e infine vengono applicati i metodi di imaging esposti in precendenza a una serie di pazienti affetti da tale patologia, studiandone i parametri e come questi variano in base alle zone analizzate del rene.
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11

Schmitt, Christiane [Verfasser], and Marc [Akademischer Betreuer] Regier. "Intravoxel Incoherent Motion (IVIM) MRT pelviner Lymphknoten : Stellenwert der biexponentiellen ADC-Berechnungin der Unterscheidung benigner und maligner Beckenlymphknoten beim Prostatakarzinom / Christiane Schmitt. Betreuer: Marc Regier." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1106404602/34.

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Schmitt, Christiane Verfasser], and Marc-Ulrich [Akademischer Betreuer] [Regier. "Intravoxel Incoherent Motion (IVIM) MRT pelviner Lymphknoten : Stellenwert der biexponentiellen ADC-Berechnungin der Unterscheidung benigner und maligner Beckenlymphknoten beim Prostatakarzinom / Christiane Schmitt. Betreuer: Marc Regier." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://nbn-resolving.de/urn:nbn:de:gbv:18-79077.

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13

Alison, Marianne. "Imagerie fonctionnelle du placenta en IRM." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA112329.

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L’insuffisance placentaire par défaut de vascularisation est une pathologie fréquente de la grossesse, de diagnostic difficile, avec des complications potentiellement graves (retard de croissance intra utérin, prééclampsie). L’objectif de ce travail de Thèse a été de développer l’IRM fonctionnelle multiparamétrique pour l’exploration du placenta à 4.7 T chez la rate gestante. Matériel et méthode : L’IRM de diffusion (SE- EPI DWI) avec analyse IVIM et l’IRM dynamique avec injection de gadolinium (DCE) et haute résolution temporelle (&lt; 1s) ont été développées puis étudiées sur un modèle murin
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14

Franco, Martina. "La risonanza magnetica in diffusione per applicazioni oncologiche al cervello." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018.

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Una degenerazione cancerosa può colpire qualsiasi parte del sistema nervoso centrale in diverse forme. Il registro tumori stima ogni anno in Italia 5.700 casi di tumore del sistema nervoso centrale (dati 2012). Tuttavia, questi tumori sono abbastanza rari e rappresentano l'1.3% di tutti i tumori. Più frequenti sono tumori che si formano all'interno del cervello ma che originano da cellule metastatiche provenienti da altri distretti, come la mammella, il fegato o il polmone. Negli ultimi anni le nuove tecniche chirurgiche consentono di asportare tumori, un tempo considerati inoperabili. L'inter
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15

Faye, Nathalie. "Thérapie cellulaire de l’angiogenèse tumorale : évaluation par imagerie morphologique et fonctionnelle en IRM et vidéomicroscopie de fluorescence." Thesis, Paris 11, 2011. http://www.theses.fr/2011PA112248/document.

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Introduction : L’angiogenèse tumorale conduit au développement de nouveaux vaisseaux destinés à permettre la croissance de la tumeur. Les vaisseaux tumoraux sont caractérisés notamment par des anomalies des cellules murales (cellules musculaires périvasculaires), responsables d’anomalies de la fonctionnalité et de la maturation. Dans ce travail de thèse, nous avons étudié un modèle tumoral de thérapie cellulaire par injection de cellules murales en IRM et vidéomicroscopie de fluorescence. Matériels et méthodes : Notre étude a porté sur un modèle sous cutané de carcinome épidermoïde chez la sou
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16

Rapacchi, Stanislas. "Low b-values diffusion weighted imaging of the in vivo human heart." Thesis, Lyon 1, 2011. http://www.theses.fr/2011LYO10012/document.

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L'Imagerie par Résonance Magnétique pondérée en Diffusion (IRM-D) permet l'accès à l'information structurelle des tissus au travers de la lecture du mouvement brownien des molécules d'eau. Ses applications sont nombreuses en imagerie cérébrale, tant en milieu clinique qu'en recherche. Néanmoins le mouvement physiologique créé une perte de signal supplémentaire au cours de l'encodage de la diffusion. Cette perte de signal liée au mouvement limite les applications de l'IRM-D quant à l'imagerie cardiaque. L'utilisation de faibles valeurs de pondération (b) réduit cette sensibilité mais permet seu
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17

Sohlberg, Sara. "Placental Function : An Epidemiological and Magnetic Resonance Study." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-239294.

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Placental function is central for normal pregnancy and in many of the major pregnancy disorders. We used magnetic resonance imaging techniques to investigate placental function in normal pregnancy, in early and late preeclampsia and in intrauterine growth restriction. We also investigated maternal body mass index and height, as risk factors for preeclampsia. A high body mass index and a short maternal stature increase the risk of preeclampsia, of all severities. The association seems especially strong between short stature and early preeclampsia, and a high body mass index and late preeclampsi
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18

Faye, Nathalie. "Thérapie cellulaire de l'angiogenèse tumorale : évaluation par imagerie morphologique et fonctionnelle en IRM et vidéomicroscopie de fluorescence." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00736731.

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Introduction : L'angiogenèse tumorale conduit au développement de nouveaux vaisseaux destinés à permettre la croissance de la tumeur. Les vaisseaux tumoraux sont caractérisés notamment par des anomalies des cellules murales (cellules musculaires périvasculaires), responsables d'anomalies de la fonctionnalité et de la maturation. Dans ce travail de thèse, nous avons étudié un modèle tumoral de thérapie cellulaire par injection de cellules murales en IRM et vidéomicroscopie de fluorescence. Matériels et méthodes : Notre étude a porté sur un modèle sous cutané de carcinome épidermoïde chez la sou
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De, Luca Alberto. "Moving beyond DTI: non-gaussian diffusion in the brain and skeletal muscle." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3424776.

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Diffusion Magnetic Resonance Imaging (dMRI) is a diagnostic technique able to provide in- vivo measures that are related to the microstructure of tissues. Thanks to the sensitivity to microstructural tissue changes, Diffusion Weighted Imaging (DWI) and derived metrics, as the Apparent Diffusion Coefficient (ADC) , became the gold standard for the detection of strokes and ischemia since the early 90‟s. In 1994 Basser and colleagues introduced Diffusion Tensor Imaging (DTI), the first quantification approach able to capture the anisotropy of the diffusion process in in-vivo biological tissues. C
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Tsai, Yu-Chen, and 蔡雨辰. "Free-Breathing IVIM Imaging in the Abdomen." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/06668384191877271383.

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碩士<br>國立臺灣科技大學<br>電機工程系<br>103<br>Intravoxel incoherent motion (IVIM) method based on diffusion-weighted imaging (DWI) is a method to acquire both diffusion and perfusion related information of tissue. Although IVIM has been shown useful in brain related applications. However, using it in abdominal imaging is relatively challenging. The major problem is the displacement of abdominal organs due to respiratory motion during the scan procedure. We propose a free-breathing self-calibrating algorithm to reduce artifacts in IVIM maps. The algorithm identified images hampering IVIM curve fitting and
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Wang, Sin-Jhe, and 王信哲. "Mass Detection and Quantitation in Breast IVIM-MRI using Constrained Energy Minimization." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/11054338628171561522.

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碩士<br>國立中興大學<br>電機工程學系所<br>103<br>In this thesis we have developed an automatic tumor detection method by using multispectral magnetic resonance imaging (MRI) technology. The MRI provides high contrast images that can be used for image analysis. The recent development of intravoxel incoherent motion (IVIM) diffusion-weighted imaging and other special imaging techniques are used for tumor detection. We use Magnetic resonance (MR) image and DWI-MR images for the experiment to detect breast cancer. Images obtained in the breast area from healthy subjects and patients were analyzed in terms of an
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Yang, Bo-Hao, and 楊博皓. "Quantitative Analysis of IVIM-MRI in breast suspicious lesions using nonlinear SVM." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/21636354831606156646.

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Chao, You-Kuan, and 趙又寬. "Quantitative Measurement of Breast Tissue on Intravoxel Incoherent Motion(IVIM) MR Image." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/rxru28.

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碩士<br>國立中興大學<br>通訊工程研究所<br>106<br>Breast cancer is one of the top ten cause of death among women in the world. Breast density is positively correlated with breast cancer. In recent years, Magnetic Resonance Imaging has gradually taken the place of traditional X-ray and ultrasound detection as a tool for breast cancer screening. Using the MR image not only has no radiation problems, but also has excellent image resolution. Therefore, we developed a method for classifying breast tissue using IVIM MR images. MR images such as T1, T2, and PD were used as inputs for glandular detection. In order to
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Hu, Wei-Hsuan, and 胡維軒. "Exploring the Effectiveness of Breast Tumor Detection Method on IVIM-MR Image." Thesis, 2019. http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22107NCHU5650002%22.&searchmode=basic.

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碩士<br>國立中興大學<br>通訊工程研究所<br>107<br>Breast magnetic resonance imaging (MRI) is a widely used examination tool in recent years. It provides high image contrast, no radiation problem and has a good effect on breast cancer detection. Recently, special screening techniques such as Intravoxel incoherent motion (IVIM) Diffusion weight imaging (DWI) have been developed and can be used without contrast agent. In this thesis, IVIM technology was applied to the detection of breast tumors. This technique can assist doctors diagnose to the location of the disease accurately without contrast agent. In this s
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Huang, Po-Wen, and 黃柏文. "Breast Tissue Classification based on Intra-voxel Incoherent Motion (IVIM-MRI) Histogram Analysis." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/03410761024619505572.

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碩士<br>國立中興大學<br>電機工程學系所<br>104<br>Breast cancer is an important cause of death and disease for women in the world. It is required for the diagnosis and treatment of breast cancer research. In recent years, MRI is gradually replacing the traditional X-ray photography and ultrasound to detect breast cancer as an inspection tool. MRI is not only no radiation problem but also more excellent on the image resolution and contrast. However, when MRI use on breast examination, it must be injected the contrast agent. The contrast agent is toxicity, so some patients may have an allergy to contrast agents
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Chang, Yu-Tzu, and 張育慈. "Breast lesions detection using Intra-voxel Incoherent Motion (IVIM-MRI) with AIHT contrast enhancement method." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/82814115417301272826.

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碩士<br>國立中興大學<br>電機工程學系所<br>104<br>In this thesis we have used a contrast enhancement method by using adaptive inverse hyperbolic tangent (AIHT) algorithm in the intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI).The AIHT technology for accomplishing contrast enhancement have been developed an automatic tumor detection method. The AIHT algorithm is capable of enhancing the global contrast of the original image adaptively while making the image features stand out simultaneously. Hence, the AIHT algorithm is used in IVIM-MRI which not only no need to use contrast agents that
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Chien, Ning, and 簡寧. "Characterization of Breast Tumors: Comparison among Diffusion Kurtosis Imaging (DKI) and Intravoxel Incoherent Motion (IVIM)." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/zx8mgj.

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碩士<br>國立臺灣大學<br>臨床醫學研究所<br>107<br>Abstract Background Breast cancer is the most commonly diagnosed cancer among women in Taiwan. Breast magnetic resonance imaging (MRI) is a sensitive imaging technique to assess breast cancer but its effectiveness still remains to be improved. Objectives Our study aim was to assess MRI diagnostic accuracy for breast lesions by comparing quantitative parameters derived from 1) diffusion-weighted imaging (DWI), 2) diffusion kurtosis imaging (DKI), 3) intravoxel incoherent motion (IVIM) and 4) dynamic contrast-enhanced MRI (DCE-MRI) and to explore an optimal mode
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Chang, Yung-Chieh, and 張詠傑. "IVIM-DWI MRI of Allograft Kidneys in 48 hours after Transplantation: A Semi-automatic Quantitative Analysis." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/45913440866778452720.

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碩士<br>國立中興大學<br>電機工程學系所<br>103<br>A successful kidney transplant for the patients with renal failure of end stage is the best treatment, but most of kidney transplant patients have delayed graft function phenomenon. The possible causes of postoperative complications, such as arterial stenosis, venous thrombosis or renal ischemia-reperfusion injury, and the results are tend to increase the immunogenicity and the risk of acute rejection by the foreign graft hence reduce survival rate. Patients with severe kidney disease execute the magnetic resonance imaging (MRI) examination with gadolinium-con
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Liao, Meng-Chieh, and 廖孟潔. "Estimation of pseudo-diffusion coefficient D* using different settings of low b-values in liver IVIM imaging." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/52272318333538145672.

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碩士<br>國立臺灣大學<br>生醫電子與資訊學研究所<br>104<br>The purpose of this study was to investigate the effects of low b-value settings on the estimation of pseudo-diffusion coefficient D* in human liver IVIM MR imaging. In this IRB approved study, 14 subjects (M/F 6/8, mean age 26.81±4.62 y) underwent IVIM diffusion-weighted magnetic resonance imaging on a Philip 3T scanner using sixteen b values (0, 5, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, 100, 200, 400, 800 s/mm2) with navigator to reduce influences from respiratory motion. Signals as a function of b-value were used to derive three parameters in IVIM equa
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