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Journal articles on the topic 'IVCIM'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Hindustan, college of Engineering. "Using the Indirect Vector Control Method for Induction Motor Speed on Network Based Controller." Journal of Engineering Technology and Sciences 02, no. 03 (2025): 01–03. https://doi.org/10.5281/zenodo.14970919.

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<em>The research outlines a thorough explanation along with implementation details of intelligent controllers for speed control systems of induction motors which use the indirect vector control method. A complete mathematical description and MATLAB simulation of the field orientation control (FOC) induction motor is provided for studying a 70 HP (42KW) cage type induction motor. This document evaluates the performance output of three control systems through PI fuzzy and neural networks evaluation.</em> <em>The current method eliminates the requirement of speed and flux sensors because their in

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Jain, Jitendra Kr, Sandip Ghosh, and Somnath Maity. "Dynamic controller design for an IVCIM." IET Electric Power Applications 13, no. 8 (2019): 1167–76. http://dx.doi.org/10.1049/iet-epa.2018.5695.

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Randon, Matthieu, and Rachid Abbas. "The In Vivo Effect of a Prostaglandin on the Conjunctival Goblet Cells." Ophthalmology – Open Journal 5, no. 1 (2022): 4–9. http://dx.doi.org/10.17140/ooj-5-123.

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Introduction To evaluate the density of conjunctival goblet cells (GCs) from in vivo confocal microscopy (IVCM) and impression cytology (IC) and mucin expression in ten glaucomatous patients treated with preservative-free latanoprost (Monoprost®) Methods Ten glaucomatous patients (10 eyes) were enrolled. Conjunctiva was examined clinically and morphologically by IVCM and IC. Both IVCM and IC were performed at baseline, and after the 1st and 4th month of Monoprost® therapy. GC density (GCD) in cells⁄mm2 was the main outcome measurement. Results At baseline, mean GCD was 147+/-78 cells/mm2 for I

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Federau, Christian, Max Wintermark, Soren Christensen, et al. "Collateral blood flow measurement with intravoxel incoherent motion perfusion imaging in hyperacute brain stroke." Neurology 92, no. 21 (2019): e2462-e2471. http://dx.doi.org/10.1212/wnl.0000000000007538.

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ObjectiveTo determine if intravoxel incoherent motion (IVIM) magnetic resonance perfusion can measure the quality of the collateral blood flow in the penumbra in hyperacute stroke.MethodsA 6 b values IVIM MRI sequence was acquired in stroke patients with large vessel occlusion imaged <16 hours of last seen well. IVIM perfusion measures were evaluated in regions of interest drawn in the infarct core (D < 600 mm2/s), in the corresponding region in the contralateral hemisphere, and in the dynamic susceptibility contrast penumbra. In patients with a penumbra >15 mL, images were reviewed f

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Wang, Ellen F., Stuti L. Misra, and Dipika V. Patel. "In Vivo Confocal Microscopy of the Human Cornea in the Assessment of Peripheral Neuropathy and Systemic Diseases." BioMed Research International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/951081.

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In vivo confocal microscopy (IVCM) of the living human cornea offers the ability to perform repeated imaging without tissue damage. Studies using corneal IVCM have led to significant contributions to scientific and clinical knowledge of the living cornea in health and pathological states. Recently the application of corneal IVCM beyond ophthalmology to wider clinical and research fields has been demonstrated. Abnormalities of the corneal subbasal nerve plexus have been associated with many forms of peripheral neuropathy and Langerhans cells correlate with systemic inflammatory states. There is

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Alshehri, Fahad. "Understanding of Saudi Population on the Usage of Intravenous Contrast Media Injections in Radiology." Journal of Umm Al-Qura University for Medical Sciences 9, no. 2 (2023): 63–68. http://dx.doi.org/10.54940/ms40276882.

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Background: Intravenous contrast media (IVCM) in radiology are extremely important for accurate diagnosis and are used daily all over the globe. These contract media are very safe if administered correctly. However, adverse events have also been reported. This study was undertaken to determine the understanding of the patients towards the usage of IVCM in radiology. Methods: This is a cross-sectional study conducted on patients recommended for IVCM-mediated radiological examinations. The data were collected by face-to-face interactions using the self-administered questionnaire before IVCM admi

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Leckelt, Janine, Pedro Guimarães, Annett Kott, Alfredo Ruggeri, Oliver Stachs, and Simone Baltrusch. "Early detection of diabetic neuropathy by investigating CNFL and IENFD in thy1-YFP mice." Journal of Endocrinology 231, no. 2 (2016): 147–57. http://dx.doi.org/10.1530/joe-16-0284.

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Small fiber neuropathy is one of the most common and painful long-term complications of diabetes mellitus. Examination of the sub-basal corneal nerve plexus is a promising surrogate marker of diabetic neuropathy. To investigate the efficacy, reliability and reproducibility of in vivo corneal confocal microscopy (IVCCM), we used thy1-YFP mice, which express yellow fluorescence protein (YFP) in nerve fibers. 4 weeks after multiple low-dose injections of streptozotocin, thy1-YFP mice showed manifest diabetes. Subsequent application of insulin-releasing pellets for 8 weeks resulted in a significan

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Shust, Pavel M., and Victor Dostov. "Implementing innovative customer due diligence: proposal for universal model." Journal of Money Laundering Control 23, no. 4 (2020): 871–84. http://dx.doi.org/10.1108/jmlc-01-2020-0007.

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Purpose The purpose of this paper is to present the identification-verification-confirmation of identity (IVCid) model that can be used to retroactively analyze the existing customer identification programs and devise new ones that can be used in face-to-face or non-face-to-face environment. Design/methodology/approach This paper outlines the main elements of the customer due diligence (CDD) process and identifies those which may present a barrier to the customers. It then outlines the IVCid model. The model is used to analyze existing CDD approaches in physical presence, using reliable databa

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Lee, Cheng-Chun, Kuang-Hsi Chang, Feng-Mao Chiu, et al. "Using IVIM Parameters to Differentiate Prostate Cancer and Contralateral Normal Tissue through Fusion of MRI Images with Whole-Mount Pathology Specimen Images by Control Point Registration Method." Diagnostics 11, no. 12 (2021): 2340. http://dx.doi.org/10.3390/diagnostics11122340.

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The intravoxel incoherent motion (IVIM) model may enhance the clinical value of multiparametric magnetic resonance imaging (mpMRI) in the detection of prostate cancer (PCa). However, while past IVIM modeling studies have shown promise, they have also reported inconsistent results and limitations, underscoring the need to further enhance the accuracy of IVIM modeling for PCa detection. Therefore, this study utilized the control point registration toolbox function in MATLAB to fuse T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) MRI images with whole-mount pathology specimen imag

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Wang, Hongyan, Lixia Zhu, Guohua Li, Menzhe Zuo, Xi Ma, and Jianliang Wang. "Perfusion parameters of intravoxel incoherent motion based on tumor edge region of interest in cervical cancer: evaluation of differentiation and correlation with dynamic contrast-enhanced MRI." Acta Radiologica 61, no. 8 (2019): 1087–95. http://dx.doi.org/10.1177/0284185119890086.

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Background Intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) is a functional magnetic resonance imaging (MRI) sequence. Purpose To evaluate the value of perfusion parameters derived from IVIM-DWI based on tumor edge region of interest (ROI) in differentiation in cervical cancer and investigate the relationship between IVIM and dynamic contrast-enhanced MRI (DCE-MRI). Material and Methods Thirty-three patients with pathologically diagnosed squamous cell carcinoma who underwent IVIM-DWI (nine b-values: 1–1000 s/mm2) and DCE-MRI were retrospectively assessed in this study. Para

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Spinner, Georg R., Deuster Constantin von, Kerem C. Tezcan, Christian T. Stoeck, and Sebastian Kozerke. "Bayesian intravoxel incoherent motion parameter mapping in the human heart." Journal of Cardiovascular Magnetic Resonance 19, no. 1 (2017): 85. https://doi.org/10.1186/s12968-017-0391-1.

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<strong>Background: </strong>Intravoxel incoherent motion (IVIM) imaging of diffusion and perfusion in the heart suffers from high parameter estimation error. The purpose of this work is to improve cardiac IVIM parameter mapping using Bayesian inference.<strong>Methods: </strong>A second-order motion-compensated diffusion weighted spin-echo sequence with navigator-based slice tracking was implemented to collect cardiac IVIM data in early systole in eight healthy subjects on a clinical 1.5 T CMR system. IVIM data were encoded along six gradient optimized directions with b-values of 0–300 s/mm<s

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Yang, Xinyue, Xiaojuan Xiao, Baolan Lu, Yan Chen, Ziqiang Wen, and Shenping Yu. "Perfusion-sensitive parameters of intravoxel incoherent motion MRI in rectal cancer: evaluation of reproducibility and correlation with dynamic contrast-enhanced MRI." Acta Radiologica 60, no. 5 (2018): 569–77. http://dx.doi.org/10.1177/0284185118791201.

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Background Intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI) acquires tumor perfusion information without injection of contrast medium, which is promising in tumor assessment. However, its consistency with dynamic contrast-enhanced MRI (DCE-MRI), a more widely used method for tumor perfusion evaluation, is not revealed in rectal cancer. Purpose In this study, we aimed to investigate the correlation of perfusion-sensitive parameters derived from IVIM-MRI with DCE-MRI and measurement reproducibility of IVIM-MRI parameters in rectal cancer. Material and Methods Forty-seven rectal

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Monte, Jithsa R., Melissa T. Hooijmans, Martijn Froeling, et al. "The repeatability of bilateral diffusion tensor imaging (DTI) in the upper leg muscles of healthy adults." European Radiology 30, no. 3 (2019): 1709–18. http://dx.doi.org/10.1007/s00330-019-06403-5.

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Abstract Objectives Assessment of the repeatability of diffusion parameter estimations in the upper leg muscles of healthy adults over the time course of 2 weeks, from a simultaneous bilateral upper leg DTI measurement. Methods SE-EPI DTI datasets were acquired at 3 T in the upper legs of 15 active adults at a time interval of 2 weeks. ROIs were manually drawn for four quadriceps and three hamstring muscles of both legs. The following DTI parameters were analyzed: 1st, 2nd, and 3rd eigenvalue (λ1, λ2, and λ3), mean diffusivity (MD), and fractional anisotropy (FA). DTI parameters per muscle wer

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Malagi, Archana Vadiraj, Sivachander Shivaji, Devasenathipathy Kandasamy, et al. "Pancreatic Mass Characterization Using IVIM-DKI MRI and Machine Learning-Based Multi-Parametric Texture Analysis." Bioengineering 10, no. 1 (2023): 83. http://dx.doi.org/10.3390/bioengineering10010083.

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Non-invasive characterization of pancreatic masses aids in the management of pancreatic lesions. Intravoxel incoherent motion-diffusion kurtosis imaging (IVIM-DKI) and machine learning-based texture analysis was used to differentiate pancreatic masses such as pancreatic ductal adenocarcinoma (PDAC), pancreatic neuroendocrine tumor (pNET), solid pseudopapillary epithelial neoplasm (SPEN), and mass-forming chronic pancreatitis (MFCP). A total of forty-eight biopsy-proven patients with pancreatic masses were recruited and classified into pNET (n = 13), MFCP (n = 6), SPEN (n = 4), and PDAC (n = 25

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Li, Ming, Xiaodan Xu, Kaijian Xia, et al. "Comparison of Diagnostic Performance between Perfusion-Related Intravoxel Incoherent Motion DWI and Dynamic Contrast-Enhanced MRI in Rectal Cancer." Computational and Mathematical Methods in Medicine 2021 (July 29, 2021): 1–7. http://dx.doi.org/10.1155/2021/5095940.

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This study was aimed to determine the diagnostic performance of perfusion-related parameters derived from intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) by comparing them with quantitative parameters from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on differentiation grades of rectal cancer. We retrospectively analyzed 98 patients with rectal cancer. Perfusion-related IVIM parameters ( D ∗ , f , and f · D ∗ ) and quantitative DCE parameters ( K trans , K ep , V e , and V p ) were obtained by plotting the volume-of-interest on in-house software. Furt

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Zhao, Yinghua, Qun Zhang, Wei Li, et al. "Assessment of Correlation between Intravoxel Incoherent Motion Diffusion Weighted MR Imaging and Dynamic Contrast-Enhanced MR Imaging of Sacroiliitis with Ankylosing Spondylitis." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/8135863.

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The relationships between IVIM and DCE-MRI parameters in AS are not clear. We explore the correlation between intravoxel incoherent motion (IVIM) diffusion weighted imaging (DWI) and dynamic contrast-enhanced (DCE) parameters obtained on MR images in patients with ankylosing spondylitis (AS). Forty-four patients with AS were prospectively examined using a 1.5-T MR system. IVIM DWI was performed with 11 b values (range, 0–800 s/mm2) for all patients. The correlation coefficients between IVIM and DCE-MRI parameters were analyzed using Spearman’s method. Our results showed that intra- and interob

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Zhu, Guangming, Christian Federau, Max Wintermark, et al. "Comparison of MRI IVIM and MR perfusion imaging in acute ischemic stroke due to large vessel occlusion." International Journal of Stroke 15, no. 3 (2019): 332–42. http://dx.doi.org/10.1177/1747493019873515.

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Purpose Intravoxel incoherent motion is a diffusion-weighted imaging magnetic resonance imaging technique that measures microvascular perfusion from a multi-b value sequence. Intravoxel incoherent motion microvascular perfusion has not been directly compared to conventional dynamic susceptibility contrast perfusion-weighted imaging in the context of acute ischemic stroke. We determined the degree of correlation between perfusion-weighted imaging and intravoxel incoherent motion parameter maps in patients with acute ischemic stroke. Methods We performed a retrospective cohort study of acute isc

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Wang, Jia-Song, Ya-Li Du, Nan Deng, et al. "Characteristics of In Vitro Culture and In Vivo Confocal Microscopy in Patients with Fungal Keratitis in a Tertiary Referral Hospital in Central China." Microorganisms 11, no. 2 (2023): 406. http://dx.doi.org/10.3390/microorganisms11020406.

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Purpose: To investigate the characteristics of in vitro culture and in vivo confocal microscopy (IVCM) in patients with fungal keratitis (FK) presented in a tertiary referral hospital in central China. Methods: In this noncomparative retrospective study, patients with the diagnosis of FK between October 2021 and November 2022 were reviewed. An IVCM and fungal culture (corneal scraping specimens) were performed, and the characteristics were analyzed. Results: During October 2021 and November 2022, 85 patients were diagnosed with FK. From 63 culture-positive cases, 8 species of fungus were ident

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Fournet, Gabrielle, Jing-Rebecca Li, Alex M. Cerjanic, Bradley P. Sutton, Luisa Ciobanu, and Denis Le Bihan. "A two-pool model to describe the IVIM cerebral perfusion." Journal of Cerebral Blood Flow & Metabolism 37, no. 8 (2016): 2987–3000. http://dx.doi.org/10.1177/0271678x16681310.

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IntraVoxel Incoherent Motion (IVIM) is a magnetic resonance imaging (MRI) technique capable of measuring perfusion-related parameters. In this manuscript, we show that the mono-exponential model commonly used to process IVIM data might be challenged, especially at short diffusion times. Eleven rat datasets were acquired at 7T using a diffusion-weighted pulsed gradient spin echo sequence with b-values ranging from 7 to 2500 s/mm2 at three diffusion times. The IVIM signals, obtained by removing the diffusion component from the raw MR signal, were fitted to the standard mono-exponential model, a

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Hara, Shoko, Masaaki Hori, Ryo Ueda, et al. "Intravoxel incoherent motion perfusion in patients with Moyamoya disease: comparison with 15O-gas positron emission tomography." Acta Radiologica Open 8, no. 5 (2019): 205846011984658. http://dx.doi.org/10.1177/2058460119846587.

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Background Intravoxel incoherent motion magnetic resonance imaging (IVIM) enables non-invasive measurement of brain perfusion. Purpose To investigate whether IVIM could be used to evaluate the hemodynamic disturbance of Moyamoya disease (MMD) by comparison with the gold-standard 15O-gas positron emission tomography (PET) method. Material and Methods Ten consecutive patients with MMD (six women; mean age = 42.8 years) and 10 age-matched healthy controls were evaluated by diffusion-weighted images with 12 different b values in the range of 0–900 s/mm2 and 15O-gas PET. Tomographic maps of IVIM pa

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Arakane, Takayuki, Masahiro Okada, Yujiro Nakazawa, et al. "Comparison between Intravoxel Incoherent Motion and Splenic Volumetry to Predict Hepatic Fibrosis Staging in Preoperative Patients." Diagnostics 13, no. 20 (2023): 3200. http://dx.doi.org/10.3390/diagnostics13203200.

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Intravoxel incoherent motion (IVIM) and splenic volumetry (SV) for hepatic fibrosis (HF) prediction have been reported to be effective. Our purpose is to compare the HF prediction of IVIM and SV in 67 patients with pathologically staged HF. SV was divided by body surface area (BSA). IVIM indices, such as slow diffusion-coefficient related to molecular diffusion (D), fast diffusion-coefficient related to perfusion in microvessels (D*), apparent diffusion-coefficient (ADC), and perfusion related diffusion-fraction (f), were calculated by two observers (R1/R2). D (p = 0.718 for R1, p = 0.087 for

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Lipiński, Kamil, and Piotr Bogorodzki. "Evaluation of Whole Brain Intravoxel Incoherent Motion (IVIM) Imaging." Diagnostics 14, no. 6 (2024): 653. http://dx.doi.org/10.3390/diagnostics14060653.

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Intravoxel Incoherent Motion (IVIM) imaging provides non-invasive perfusion measurements, eliminating the need for contrast agents. This work explores the feasibility of IVIM imaging in whole brain perfusion studies, where an isotropic 1 mm voxel is widely accepted as a standard. This study follows the validity of a time-limited, precise, segmentation-ready whole-brain IVIM protocol suitable for clinical reality. To assess the influence of SNR on the estimation of S0, f, D*, and D IVIM parameters, a series of measurements and simulations were performed in MATLAB for the following three estimat

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Minh Duc, Nguyen. "The diagnostic function of intravoxel incoherent motion for distinguishing between pilocytic astrocytoma and ependymoma." PLOS ONE 16, no. 3 (2021): e0247899. http://dx.doi.org/10.1371/journal.pone.0247899.

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Introduction Intravoxel incoherent motion (IVIM) imaging concurrently measures diffusion and perfusion parameters and has potential applications for brain tumor classification. However, the effectiveness of IVIM for the differentiation between pilocytic astrocytoma and ependymoma has not been verified. The aim of this study was to determine the potential diagnostic role of IVIM for the distinction between ependymoma and pilocytic astrocytoma. Methods Between February 2019 and October 2020, 22 children (15 males and 7 females; median age 4 years) with either ependymoma or pilocytic astrocytoma

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Alzerwi, Nasser A. N. "Effect of the Profit and Teaching Status of Hospitals on the Patterns and Outcomes of Abdominal Aorta and Inferior Vena Cava Injuries after Severe Abdominal Trauma." Emergency Medicine International 2023 (August 11, 2023): 1–8. http://dx.doi.org/10.1155/2023/5616007.

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Background. The inferior vena cava (IVC) and the abdominal aorta (AA) are two important blood vessels located in the abdomen. The outcomes of such injuries rely heavily on the experience, expertise, and resources available at the hospital where the patient is treated. However, our current understanding of the potential impact of the hospital profit and teaching status on surgical outcomes in the context of traumatic injuries to the IVC and AA remains limited, making it important to investigate the potential association between these hospital characteristics and patient outcomes to enhance the

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Galanakis, Nikolaos, Thomas G. Maris, Georgios Kalaitzakis, et al. "Evaluation of foot hypoperfusion and estimation of percutaneous transluminal angioplasty outcome in patients with critical limb ischemia using intravoxel incoherent motion microperfusion MRI." British Journal of Radiology 94, no. 1125 (2021): 20210215. http://dx.doi.org/10.1259/bjr.20210215.

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Objectives: To emerge hypoperfusion of lower limbs in patients with critical limb ischemia (CLI) using Intravoxel Incoherent Motion microperfusion magnetic resonance imaging (IVIM-MRI). Moreover to examine the ability of IVIM-MRI to differentiate patients with severe peripheral arterial disease (PAD) from normal subjects and evaluate the percutaneous transluminal angioplasty (PTA) results in patients with CLI. Methods: Eight patients who presented with CLI and six healthy volunteers were examined. The patients underwent IVIM-MRI of lower extremity before and following PTA. The imaging protocol

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Merisaari, Harri, and Christian Federau. "Signal to noise and b-value analysis for optimal intra-voxel incoherent motion imaging in the brain." PLOS ONE 16, no. 9 (2021): e0257545. http://dx.doi.org/10.1371/journal.pone.0257545.

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Intravoxel incoherent motion (IVIM) is a method that can provide quantitative information about perfusion in the human body, in vivo, and without contrast agent. Unfortunately, the IVIM perfusion parameter maps are known to be relatively noisy in the brain, in particular for the pseudo-diffusion coefficient, which might hinder its potential broader use in clinical applications. Therefore, we studied the conditions to produce optimal IVIM perfusion images in the brain. IVIM imaging was performed on a 3-Tesla clinical system in four healthy volunteers, with 16 b values 0, 10, 20, 40, 80, 110, 14

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Chevallier, Olivier, Yì Xiáng J. Wáng, Kévin Guillen, Julie Pellegrinelli, Jean-Pierre Cercueil, and Romaric Loffroy. "Evidence of Tri-Exponential Decay for Liver Intravoxel Incoherent Motion MRI: A Review of Published Results and Limitations." Diagnostics 11, no. 2 (2021): 379. http://dx.doi.org/10.3390/diagnostics11020379.

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Diffusion weighted imaging (DWI) and intravoxel incoherent motion (IVIM) have been explored to assess liver tumors and diffused liver diseases. IVIM reflects the microscopic translational motions that occur in voxels in magnetic resonance (MR) DWI. In biologic tissues, molecular diffusion of water and microcirculation of blood in the capillary network can be assessed using IVIM DWI. The most commonly applied model to describe the DWI signal is a bi-exponential model, with a slow compartment of diffusion linked to pure molecular diffusion (represented by the coefficient Dslow), and a fast compa

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Gloria, Cruz, Qin Li, Liping Xu, and Wanshi Zhang. "Differentiation of diffusion coefficients to distinguish malignant and benign tumor." Journal of X-Ray Science and Technology: Clinical Applications of Diagnosis and Therapeutics 18, no. 3 (2010): 235–49. http://dx.doi.org/10.3233/xst-2010-025700257.

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Taking advantage of Diffusion Weighted Imaging (DWI) to characterize the random movement of water molecules in biological tissue, this article intends to review the Intravoxel Incoherent Motion (IVIM) theory as a valuable method to find the differentiation between malignant and benign tumor based on the microcirculation of blood in the capillaries. IVIM is measured by means of a parameter called apparent diffusion coefficient (ADC). Through the application of IVIM to the imaging processing software, it will be possible to set up an expert system with screening, discrimination, staging and ther

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Cañadas, Pilar, Marta Alberquilla García-Velasco, José Luis Hernández Verdejo, and Miguel A. Teus. "Update on Corneal Confocal Microscopy Imaging." Diagnostics 13, no. 1 (2022): 46. http://dx.doi.org/10.3390/diagnostics13010046.

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In vivo corneal confocal microscopy (IVCM) is a non-invasive ophthalmic imaging technique that provides images of the cornea at the cellular level. Despite the uses in ocular surface pathologies, in the last decades IVCM has been used to provide more knowledge in refractive surgery wound healing, in neuropathies diagnosis, etc. The observation of the corneal cells, both normal and inflammatory, and the possibility of quantification of the corneal nerve density with manual or automated tools, makes IVCM have a significant potential to improve the diagnosis and prognosis in several systemic and

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Leonardi, Andrea, Gianni Carraro, Rocco Luigi Modugno, et al. "Cornea verticillata in Fabry disease: a comparative study between slit-lamp examination and in vivo corneal confocal microscopy." British Journal of Ophthalmology 104, no. 5 (2019): 718–22. http://dx.doi.org/10.1136/bjophthalmol-2019-314249.

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PurposeTo compare the diagnostic power of slit-lamp examination with the in vivo corneal confocal microscopy (IVCM) as the gold standard in assessing the presence of corneal epithelial deposits in patients with Fabry disease (FD).MethodsFourteen patients with FD (4 males, 10 females; mean age, 46.8 years) and eight healthy controls (4 males, 4 females; mean age, 36.75 years) were included. All subjects underwent slit-lamp examination and IVCM of both central and peripheral corneal quadrants with the Heidelberg Retina Tomograph-III in combination with the Rostock Cornea Module.ResultsIn patient

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Zheng, Xiaomin, Cuiping Li, Lufeng Zhang, et al. "Combining Intravoxel Incoherent Motion Diffusion Weighted Imaging and Texture Analysis for a Nomogram to Predict Early Treatment Response to Concurrent Chemoradiotherapy in Cervical Cancer Patients." Journal of Oncology 2021 (December 24, 2021): 1–10. http://dx.doi.org/10.1155/2021/9345353.

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This study aimed to predict early treatment response to concurrent chemoradiotherapy (CCRT) by combining intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) with texture analysis (TA) for cervical cancer patients and to develop a nomogram for estimating the risk of residual tumor. Ninty-three cervical cancer patients underwent conventional MRI and IVIM-DWI before CCRT. We conducted TA using T2WI. The patients were allocated to partial response (PR) and complete response (CR) groups on the basis of posttreatment MRI. Multivariate logistic regression analysis on IVIM-DWI parameter

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Altıntaş, Ayşe, Ayse Yildiz-Tas, Sezen Yilmaz, et al. "A novel investigation method for axonal damage in neuromyelitis optica spectrum disorder: In vivo corneal confocal microscopy." Multiple Sclerosis Journal - Experimental, Translational and Clinical 7, no. 1 (2021): 205521732199806. http://dx.doi.org/10.1177/2055217321998060.

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Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory autoimmune disorder that damages optic nerves, brainstem, and spinal cord. In vivo corneal confocal microscopy (IVCM) is a noninvasive technique that provides corneal images with dendritic cells (DCs) and corneal subbasal nerve plexus (SBP), which arises from the trigeminal nerve. Objective We investigated corneal SBP changes in NMOSD and proposed IVCM as a potential new disease severity biomarker for NMOSD. Methods Seventeen age-sex matched NMOSD patients and 19 healthy participants underwent complete neurologic and

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Dembski, Michał, Anna Nowińska, Klaudia Ulfik, Sławomir Teper, and Edward Wylęgała. "In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Analysis of the Microcystic Keratitis." Journal of Ophthalmology 2020 (December 17, 2020): 1–6. http://dx.doi.org/10.1155/2020/8871904.

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Purpose. To describe the findings of in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) in a case of bilateral acute microcystic epitheliopathy after daily soft contact lens wear. Methods. IVCM and AS-OCT were used in the course of the bilateral epitheliopathy of a 23-year-old patient at the acute stage of the disease and at recovery after four days of treatment. The images were analyzed and compared. Results. On AS-OCT of the right eye, general hyperreflectivity and the increased thickness of the central corneal epithelium to 150 μm with numerous hyp

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Luo, Hechuan, Ling He, Weiqin Cheng, and Sijie Gao. "The diagnostic value of intravoxel incoherent motion imaging in differentiating high-grade from low-grade gliomas: a systematic review and meta-analysis." British Journal of Radiology 94, no. 1121 (2021): 20201321. http://dx.doi.org/10.1259/bjr.20201321.

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Objective: This meta-analysis was carried out for assessing the accuracy of intravoxel incoherent motion (IVIM) parameters true diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) in differentiating low-grade gliomas (LGGs) from high-grade gliomas (HGGs). Methods: Literatures concerning IVIM in the grading of brain gliomas published prior to October 20, 2020, searched in the Embase, PubMed, and Cochrane library. Use the quality assessment of diagnostic accuracy studies 2 (QUADAS 2) to evaluate the quality of studies. We estimated the pooled sensitivity, spe

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Podgórska, Joanna, Katarzyna Pasicz, Witold Skrzyński, et al. "Perfusion-Diffusion Ratio: A New IVIM Approach in Differentiating Solid Benign and Malignant Primary Lesions of the Liver." BioMed Research International 2022 (January 15, 2022): 1–9. http://dx.doi.org/10.1155/2022/2957759.

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Introduction. In order to improve the efficacy of intravoxel incoherent motion (IVIM) parameters in characterising specific tissues, a new concept is introduced: the perfusion–diffusion ratio (PDR), which expresses the relationship between the signal S b decline rate as a result of IVIM and the rate of signal S b decline due to diffusion. The aim of this study was to investigate this novel approach in the differentiation of solid primary liver lesions. Material and Methods. Eighty-three patients referred for liver MRI between August 2017 and January 2020 with a suspected liver tumour were pros

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Liu, Xiang, Yi-Feng Wang, Xiao-Hui Qi, et al. "Reproducibility study of intravoxel incoherent motion and apparent diffusion coefficient parameters in normal pancreas." World Journal of Gastrointestinal Surgery 16, no. 7 (2024): 2031–39. http://dx.doi.org/10.4240/wjgs.v16.i7.2031.

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BACKGROUND The consistency of pancreatic apparent diffusion coefficient (ADC) values and intravoxel incoherent motion (IVIM) parameter values across different magnetic resonance imaging (MRI) devices significantly impacts the patient’s diagnosis and treatment. AIM To explore consistency in image quality, ADC values, and IVIM parameter values among different MRI devices in pancreatic examinations. METHODS This retrospective study was approved by the local ethics committee, and informed consent was obtained from all participants. In total, 22 healthy volunteers (10 males and 12 females) aged 24-

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Ratiphunpong, Phimphitcha, Nakarin Inmutto, Salita Angkurawaranon, Kittichai Wantanajittikul, Atita Suwannasak, and Uten Yarach. "A Pilot Study on Deep Learning With Simplified Intravoxel Incoherent Motion Diffusion-Weighted MRI Parameters for Differentiating Hepatocellular Carcinoma From Other Common Liver Masses." Topics in Magnetic Resonance Imaging 34, no. 1 (2025): e0316. https://doi.org/10.1097/rmr.0000000000000316.

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Abstract Objectives: To develop and evaluate a deep learning technique for the differentiation of hepatocellular carcinoma (HCC) using “simplified intravoxel incoherent motion (IVIM) parameters” derived from only 3 b-value images. Materials and Methods: Ninety-eight retrospective magnetic resonance imaging data were collected (68 men, 30 women; mean age 59 ± 14 years), including T2-weighted imaging with fat suppression, in-phase, out-of-phase, and diffusion-weighted imaging (b = 0, 100, 800 s/mm2). Ninety percent of data were used for stratified 10-fold cross-validation. After data preprocessi

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Hoffman, Jeremy J., Reena Yadav, Sandip Das Sanyam, et al. "Diagnosis of Fungal Keratitis in Low-Income Countries: Evaluation of Smear Microscopy, Culture, and In Vivo Confocal Microscopy in Nepal." Journal of Fungi 8, no. 9 (2022): 955. http://dx.doi.org/10.3390/jof8090955.

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Clinically diagnosing fungal keratitis (FK) is challenging; diagnosis can be assisted by investigations including in vivo confocal microscopy (IVCM), smear microscopy, and culture. The aim of this study was to estimate the sensitivity in detecting fungal keratitis (FK) using IVCM, smear microscopy, and culture in a setting with a high prevalence of FK. In this cross-sectional study nested within a prospective cohort study, consecutive microbial keratitis (MK) patients attending a tertiary-referral eye hospital in south-eastern Nepal between June 2019 and November 2020 were recruited. IVCM and

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Shi, Bin, Jiang-Ning Dong, Li-Xiang Zhang, et al. "A Combination Analysis of IVIM-DWI Biomarkers and T2WI-Based Texture Features for Tumor Differentiation Grade of Cervical Squamous Cell Carcinoma." Contrast Media & Molecular Imaging 2022 (March 17, 2022): 1–10. http://dx.doi.org/10.1155/2022/2837905.

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Purpose. To explore the value of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and texture analysis on T2-weighted imaging (T2WI) for evaluating pathological differentiation of cervical squamous cell carcinoma. Method. This retrospective study included a total of 138 patients with pathologically confirmed poor/moderate/well-differentiated (71/49/18) who underwent conventional MRI and IVIM-DWI scans. The values of ADC, D, D ∗ , and f and 58 T2WI-based texture features (18 histogram features, 24 gray-level co-occurrence matrix features, and 16 gray-level run length matrix fe

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Loh, Martin, Tobit Führes, Christoph Stuprich, et al. "Effect of simultaneous multislice imaging, slice properties, and repetition time on the measured magnetic resonance biexponential intravoxel incoherent motion in the liver." PLOS ONE 19, no. 8 (2024): e0306996. http://dx.doi.org/10.1371/journal.pone.0306996.

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Objectives This study aims to investigate the previously reported dependency of intravoxel incoherent motion (IVIM) parameters on simultaneous multislice (SMS) acquisition and repetition time (TR). This includes the influence of slice thickness, slice gaps, and slice order on measured IVIM parameters. Materials and methods Diffusion-weighted imaging (DWI) of the liver was performed on 10 healthy volunteers (aged 20–30 years) at 3T with a slice thickness of 5 mm, a slice gap of 5 mm, and a linear slice order. Diffusion-weighted images were acquired with 19 b-values (0–800 s/mm2) using both conv

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Wu, Gang, Ruyi Xie, Xuanlin Liu, Bowen Hou, Yitong Li, and Xiaoming Li. "Intravoxel incoherent motion diffusion MR and diffusion kurtosis imaging for discriminating atypical bone metastasis from benign bone lesion." British Journal of Radiology 92, no. 1100 (2019): 20190119. http://dx.doi.org/10.1259/bjr.20190119.

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Objectives: To investigate the feasibility of intravoxel incoherent motion (IVIM) diffusion MR and diffusion kurtosis imaging (DKI) in discriminating atypical bone metastasis from benign bone lesion in patients with tumors. Methods: Patients with bone lesions in lower extremity suspected of metastases were enrolled in this prospective study. IVIM diffusion MR and DKI were performed before biopsy. Apparent diffusion coefficient (ADC), true diffusion (D), perfusion fraction (f) and perfusion-related pseudodiffusion (D*) were generated with IVIM, while mean kurtosis (MK) and mean diffusion (MD) g

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Liu, Li, Zhimin Zhou, Sunyu Hua, et al. "Detection of the disease activity with ankylosing spondylitis through intravoxel incoherent motion diffusion-weighted MR imaging of sacroiliac joint." British Journal of Radiology, March 24, 2022. http://dx.doi.org/10.1259/bjr.20211074.

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Objective: To explore the value of the quantitative parameter of intravoxel incoherent motion diffusion (IVIM-DWI) at 3.0 T MRI of the sacroiliac joint in differentiating different disease activity statuses of ankylosing spondylitis (AS) and to compare it with traditional diffusion-weighted imaging (DWI) and Spondyloarthritis Research Consortium of Canada (SPARCC) score. Methods: 56 AS patients (active group, inactive group) and 24 healthy controls were included. Clinical data, quantitative parameters of IVIM-DWI MR images and the SPARCC scores were collected. The Kruskal–Wallis test was used

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Toba, Bogdana, and Neil Lagali. "Use of in vivo confocal microscopy in suspected Acanthamoeba keratitis: a 12-year real-world data study at a Swedish regional referral center." Journal of Ophthalmic Inflammation and Infection 14, no. 1 (2024). http://dx.doi.org/10.1186/s12348-024-00424-y.

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Abstract Purpose To report real-world data (RWD) on the use of in vivo confocal microscopy (IVCM) in handling cases of suspected Acanthamoeba keratitis (AK) cases at a regional referral center during a 12-year period. Methods Retrospective study of patients with suspected AK presenting at a regional referral center for IVCM in Sweden from 2010 to 2022. Demographics, symptoms, outcomes, and clinical management were analyzed, and IVCM images were interpreted. Results Of 74 included patients with suspected AK, 18 (24%) were IVCM-positive, 33 (44%) were IVCM-negative, 15 had inconclusive IVCM resu

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Luo, Lingfeng, Chen Ye, Tianxian Li, Ming Zhong, Lihui Wang, and Yuemin Zhu. "The self‐supervised fitting method based on similar neighborhood information of voxels for intravoxel incoherent motion diffusion‐weighted MRI." Medical Physics, April 14, 2025. https://doi.org/10.1002/mp.17825.

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AbstractBackgroundThe intravoxel incoherent motion (IVIM) parameter estimation is affected by noise, while existing CNN‐based fitting methods utilize neighborhood spatial features around voxels to obtain more robust parameters. However, due to the heterogeneity of tissue, neighborhood features with low similarity can lead to excessively smooth parameter maps and even loss of tissue details.PurposeTo propose a novel neural network fitting approach, IVIM‐CNNsimilar, which utilizes similar neighborhood information of voxels to assist in the estimation of IVIM parameters in diffusion‐weighted imag

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Wang, Lu, Jiechao Wang, Qinqin Yang, et al. "Improved deep learning‐based IVIM parameter estimation via the use of more “realistic” simulated brain data." Medical Physics, December 20, 2024. https://doi.org/10.1002/mp.17583.

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AbstractBackgroundDue to the low signal‐to‐noise ratio (SNR) and the limited number of b‐values, precise parameter estimation of intravoxel incoherent motion (IVIM) imaging remains an open issue to date, especially for brain imaging where the relatively small difference between D and D* easily leads to outliers and obvious graininess in estimated results.PurposeTo propose a synthetic data driven supervised learning method (SDD‐IVIM) for improving precision and noise robustness in IVIM parameter estimation without relying on real‐world data for neural network training.MethodsOn account of the a

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Wang, Qi, Guanghui Yu, Jianfeng Qiu, and Weizhao Lu. "Application of Intravoxel Incoherent Motion in Clinical Liver Imaging: A Literature Review." Journal of Magnetic Resonance Imaging, November 2023. http://dx.doi.org/10.1002/jmri.29086.

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Intravoxel incoherent motion (IVIM) modeling is a widely used double‐exponential model for describing diffusion‐weighted imaging (DWI) signal, with a slow component related to pure molecular diffusion and a fast component associated with microcirculatory perfusion, which compensates for the limitations of traditional DWI. IVIM is a noninvasive technique for obtaining liver pathological information and characterizing liver lesions, and has potential applications in the initial diagnosis and treatment monitoring of liver diseases. Recent studies have demonstrated that IVIM‐derived parameters are

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Kooreman, Ernst S., Vivian van Pelt, Marlies E. Nowee, Floris Pos, Uulke A. van der Heide, and Petra J. van Houdt. "Longitudinal Correlations Between Intravoxel Incoherent Motion (IVIM) and Dynamic Contrast-Enhanced (DCE) MRI During Radiotherapy in Prostate Cancer Patients." Frontiers in Oncology 12 (June 7, 2022). http://dx.doi.org/10.3389/fonc.2022.897130.

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PurposeIntravoxel incoherent motion (IVIM) is a promising technique that can acquire perfusion information without the use of contrast agent, contrary to the more established dynamic contrast-enhanced (DCE) technique. This is of interest for treatment response monitoring, where patients can be imaged on each treatment fraction. In this study, longitudinal correlations between IVIM- and DCE parameters were assessed in prostate cancer patients receiving radiation treatment.Materials and Methods20 prostate cancer patients were treated on a 1.5 T MR-linac with 20 x 3 or 3.1 Gy. Weekly IVIM and DCE

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Chen, Shihui, Mei‐Lan Chu, Liyuan Liang, et al. "Highly accelerated multi‐shot intravoxel incoherent motion diffusion‐weighted imaging in brain enabled by parametric POCS‐based multiplexed sensitivity encoding." NMR in Biomedicine, October 23, 2023. http://dx.doi.org/10.1002/nbm.5063.

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AbstractRecently, intravoxel incoherent motion (IVIM) diffusion‐weighted imaging (DWI) has also been demonstrated as an imaging tool for applications in neurological and neurovascular diseases. However, the use of single‐shot diffusion‐weighted echo‐planar imaging for IVIM DWI acquisition leads to suboptimal data quality: for instance, geometric distortion and deteriorated image quality at high spatial resolution. Although the recently commercialized multi‐shot acquisition methods, such as multiplexed sensitivity encoding (MUSE), can attain high‐resolution and high‐quality DWI with signal‐to‐n

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Li, Shilan, Anna Mou, Xin Li, et al. "Myocardium microcirculation study in a healthy Chinese population using 3.0-T cardiac magnetic resonance intravoxel incoherent motion imaging." Acta Radiologica, April 22, 2021, 028418512110063. http://dx.doi.org/10.1177/02841851211006311.

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Background Intravoxel incoherent motion imaging (IVIM) can non-invasively evaluate diffusion and microvascular perfusion. Purpose To explore the myocardium microcirculation of a healthy Chinese population by using cardiac magnetic resonance (CMR) IVIM. Material and Methods A total of 80 healthy volunteers (44 men, 36 women) who underwent 3.0-T CMR examination were enrolled. All participants had cardiac cine imaging and short-axis CMR-IVIM of the left ventricle (LV) using multiple b-values. The consistency of the IVIM parameters was assessed by intraclass correlation coefficient (ICC) and the B

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Hu, Guodong, Chen Ye, Ming Zhong, Chao Lei, Junpeng Qin, and Lihui Wang. "IVIM parameters mapping with artificial neural network based on mean deviation prior." Medical Physics, September 6, 2024. http://dx.doi.org/10.1002/mp.17383.

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AbstractBackgroundThe diffusion and perfusion parameters derived from intravoxel incoherent motion (IVIM) imaging provide promising biomarkers for noninvasively quantifying and managing various diseases. Nevertheless, due to the distribution gap between simulated and real datasets, the out‐of‐distribution (OOD) problem occurred in supervised learning‐based methods degrades their performance and hinders their real applications.PurposeTo address the OOD problem in supervised methods and to further improve the accuracy and stability of IVIM parameter estimation, this work proposes a novel learnin

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