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1
Jachan, Tomáš. "Analýza požadavků oceňovacích standardů RICS a jejich aplikace v posudku o ocenění majetku." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-232531.
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This diploma thesis is about the valuation of property, it is focused to requirements of international valuation standards RICS. The motivation of this thesis is popularization of using RICS standards in Czech Republic. These standards have not been translated to Czech language yet. Requirements of these standards are dispersed to many chapters in these standards. The aim of this thesis is analysis of RICS standards and their implication to valuation report according to Czech law. Analysis is made with structured approach with using systematic concept. Analysis refers to valuer, valuation process and valuation report. These objects are structured again. The results are implicated to valuation report according to Czech law and compliance to RICS standards too.
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Zhang, Jian. "The LEP Learning System, an IVSA approach." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0008/NQ39168.pdf.
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au, chrisn@npmicro com, and Christopher Jack Newell. "In vitro soil-less (IVS) rooting medium." Murdoch University, 2006. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070514.132029.
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The principle hypothesis of this thesis is that hypoxia, in agar-based media, compromises rooting in vitro. From a practical point of view this is important because most plant tissue culture activities require the material to be successfully acclimatised in a nursery environment. Compromised rooting often results in excessive losses at this stage which are costly and inconvenient. In addition, many plants with commercial and/or scientific interest remain unavailable as they are not able to be rooted and acclimatised reliably. The use of agar as a rooting medium has limited the capacity of plant tissue culture to clonally propagate many plants.
The thesis begins by demonstrating how poorly some plants respond to agar rooting media. Juvenile Chamelaucium hybrid microcuttings were pulsed with IBA 40 ìM and then placed for 3 weeks on either M1 (½ MS) or aerated in vitro soil-less substrate (IVS) (Chapter 2). IVS had 4282% rooting at the end of Stage 3 compared with 01% in agar. Shoot survival for IVS-rooted microcuttings was significantly greater than M1-rooted shoots. Pulsed shoots placed in IVS showed root primordia after 7 days. In contrast, shoots placed in agar showed no root primordia after 21 days and formed callus but did not root when subsequently placed in IVS for a further 4 weeks. The agar medium almost totally and permanently inhibited the capacity of competent shoots to form root primordia and roots.
The effectiveness of different types of aerated and non-aerated media, including IVS, were tested to validate the hypothesis (Chapter 3). Microcuttings from shoot cultures of two Australian plants Grevillea thelemanniana and Verticordia plumosa x Chamelaucium uncinatum were pulsed for 7 days on a high auxin (40 ìM IBA), agar-solidified medium in the dark. Rooting of the microcuttings was then compared on five experimental substrates: a) standard agar M1 medium (½ MS, no hormones, 8 g agar L-1), b) porous-agar medium (½ MS, no hormones, 30 g agar L-1, solidified then blended to provide aeration), c) white sand wet with liquid M1, d) white sand with M1 medium containing agar, and e) IVS. A separate experiment involved flushing the IVS soil profile with low or normal oxygen. Low and variable rooting percentages were recorded on the controls on M1 medium. Root induction and average total root length per microcutting at final harvest were significantly higher using the porous media including IVS, blended agar or white sand. The M1 medium and the addition of M1 medium to sand suppressed the percentage rooting and elongation. Flushing the IVS rooting medium with low oxygen also suppressed rooting. The experiments showed that increasing the air-filled porosity of the rooting medium has a positive effect on rooting and this is most likely due to the increased oxygen at the base of the microcutting. The role of ethylene, and the sugar and nutrients in M1 were not investigated.
The efficacy of the IVS protocol on a range of Australian herbaceous and woody species was investigated to determine whether the observed benefits were generic or plant specific (Chapter 4). Improved rooting in IVS compared to agar was shown for 28 Australian species and genotypes from the families Liliaceae, Haemodoraceae, Myrtaceae, Thymelaeaceae, Proteaceae, Goodeniaceae and Rutaceae. Twenty-seven of the 28 species rooted in IVS medium at equal or better rates than in M1. In three cases Actinodium cunninghamii, one of the Pimelea physodes genotypes and one of the Eriostemon australasius genotypes shoots did not root in M1 but showed good root development in IVS medium. With few exceptions average root length and number in microcuttings rooted in IVS was superior to those in agar medium.
To further test the resilience of the hypothesis, it was tested on nodal microcuttings of lentil which are recalcitrant to root in vitro (Chapter 5). The veracity of a published conclusion that inverted lentil microcuttings (with their base in the air) root better because of their altered polarity was also examined. It was found that, as is the case for many species, roots initiated and grew only at the proximal end of the microcutting regardless of its orientation. When the proximal end was in agar (a hypoxic environment) the rooting percentage was low (925%) even when the orientation of the microcutting was altered by inverting the culture tube. In contrast, when the proximal end of the microcutting was in an aerobic environment (from the shoot being placed upside down in agar medium or placed normally or upside down in an aerated medium) rooting percentages were higher (62100%).
Given that Stage 2 microcuttings are prepared with the objective to root and acclimatise them to nursery conditions, the duration of this activity becomes important as it can impact on plant quality and costs. The pulsing protocol and the length of time that Stage 3 cultures remain in the culture room during the rooting phase is a component of the unit cost of production of each rooted microcutting. Initially a 7-day IBA pulse was used after which the pulsed microcuttings were transferred to IVS to root. Chapter 6 shows that the pulsing period can be shortened to one day or replaced with a single auxin dip while still achieving high rooting percentages and maintaining plant quality. These materials handling improvements go some way to realising the logistical benefits of ex vitro rooting but without compromising the positive influences of hygiene and a stable environment of the in vitro environment.
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Newell, Christopher Jack. "In vitro soil-less (IVS) rooting medium." Newell, Christopher Jack (2006) In vitro soil-less (IVS) rooting medium. PhD thesis, Murdoch University, 2006. http://researchrepository.murdoch.edu.au/227/.
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The principle hypothesis of this thesis is that hypoxia, in agar-based media, compromises rooting in vitro. From a practical point of view this is important because most plant tissue culture activities require the material to be successfully acclimatised in a nursery environment. Compromised rooting often results in excessive losses at this stage which are costly and inconvenient. In addition, many plants with commercial and/or scientific interest remain unavailable as they are not able to be rooted and acclimatised reliably. The use of agar as a rooting medium has limited the capacity of plant tissue culture to clonally propagate many plants.
The thesis begins by demonstrating how poorly some plants respond to agar rooting media. Juvenile Chamelaucium hybrid microcuttings were pulsed with IBA 40 mcg M and then placed for 3 weeks on either M1 (1/2 MS) or aerated in vitro soil-less substrate (IVS) (Chapter 2). IVS had 42-82% rooting at the end of Stage 3 compared with 0-1% in agar. Shoot survival for IVS-rooted microcuttings was significantly greater than M1-rooted shoots. Pulsed shoots placed in IVS showed root primordia after 7 days. In contrast, shoots placed in agar showed no root primordia after 21 days and formed callus but did not root when subsequently placed in IVS for a further 4 weeks. The agar medium almost totally and permanently inhibited the capacity of competent shoots to form root primordia and roots.
The effectiveness of different types of aerated and non-aerated media, including IVS, were tested to validate the hypothesis (Chapter 3). Microcuttings from shoot cultures of two Australian plants Grevillea thelemanniana and Verticordia plumosa x Chamelaucium uncinatum were pulsed for 7 days on a high auxin (40 mcg M IBA), agar-solidified medium in the dark. Rooting of the microcuttings was then compared on five experimental substrates: a) standard agar M1 medium (1/2 MS, no hormones, 8 g agar L-1), b) porous-agar medium (1/2 MS, no hormones, 30 g agar L-1, solidified then blended to provide aeration), c) white sand wet with liquid M1, d) white sand with M1 medium containing agar, and e) IVS. A separate experiment involved flushing the IVS soil profile with low or normal oxygen. Low and variable rooting percentages were recorded on the controls on M1 medium. Root induction and average total root length per microcutting at final harvest were significantly higher using the porous media including IVS, blended agar or white sand. The M1 medium and the addition of M1 medium to sand suppressed the percentage rooting and elongation. Flushing the IVS rooting medium with low oxygen also suppressed rooting. The experiments showed that increasing the air-filled porosity of the rooting medium has a positive effect on rooting and this is most likely due to the increased oxygen at the base of the microcutting. The role of ethylene, and the sugar and nutrients in M1 were not investigated.
The efficacy of the IVS protocol on a range of Australian herbaceous and woody species was investigated to determine whether the observed benefits were generic or plant specific (Chapter 4). Improved rooting in IVS compared to agar was shown for 28 Australian species and genotypes from the families Liliaceae, Haemodoraceae, Myrtaceae, Thymelaeaceae, Proteaceae, Goodeniaceae and Rutaceae. Twenty-seven of the 28 species rooted in IVS medium at equal or better rates than in M1. In three cases - Actinodium cunninghamii, one of the Pimelea physodes genotypes and one of the Eriostemon australasius genotypes - shoots did not root in M1 but showed good root development in IVS medium. With few exceptions average root length and number in microcuttings rooted in IVS was superior to those in agar medium.
To further test the resilience of the hypothesis, it was tested on nodal microcuttings of lentil which are recalcitrant to root in vitro (Chapter 5). The veracity of a published conclusion that inverted lentil microcuttings (with their base in the air) root better because of their altered polarity was also examined. It was found that, as is the case for many species, roots initiated and grew only at the proximal end of the microcutting regardless of its orientation. When the proximal end was in agar (a hypoxic environment) the rooting percentage was low (9-25%) even when the orientation of the microcutting was altered by inverting the culture tube. In contrast, when the proximal end of the microcutting was in an aerobic environment (from the shoot being placed upside down in agar medium or placed normally or upside down in an aerated medium) rooting percentages were higher (62-100%).
Given that Stage 2 microcuttings are prepared with the objective to root and acclimatise them to nursery conditions, the duration of this activity becomes important as it can impact on plant quality and costs. The pulsing protocol and the length of time that Stage 3 cultures remain in the culture room during the rooting phase is a component of the unit cost of production of each rooted microcutting. Initially a 7-day IBA pulse was used after which the pulsed microcuttings were transferred to IVS to root. Chapter 6 shows that the pulsing period can be shortened to one day or replaced with a single auxin dip while still achieving high rooting percentages and maintaining plant quality. These materials handling improvements go some way to realising the logistical benefits of ex vitro rooting but without compromising the positive influences of hygiene and a stable environment of the in vitro environment.
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Lösler, Michael, Torsten Lossin, Alexander Neidhardt, and Rüdiger Lehmann. "Untersuchung zur automatisierten Bestimmung des IVS-Referenzpunktes am TWIN Radioteleskop Wettzell." Hochschule für Technik und Wirtschaft Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:520-qucosa-159760.
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Die Verknüpfung von geodätischen Raumtechniken wie GNSS, DORIS, SLR oder VLBI zur Ableitung eines geodätischen Referenzrahmens wie dem ITRF gelingt erst durch sogenannte Kolokationsstationen. Die geometrischen Beziehungen zwischen den betriebenen Raumtechniken sind dabei aus präzisen lokalen Vermessungen abzuleiten. Es wird ein Konzept zur automatisierten Bestimmung des IVS-Referenzpunktes am TWIN Radioteleskop Wettzell vorgestellt. Erste Untersuchungsergebnisse werden präsentiert.
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Lösler, Michael, Torsten Lossin, Alexander Neidhardt, and Rüdiger Lehmann. "Untersuchung zur automatisierten Bestimmung des IVS-Referenzpunktes am TWIN Radioteleskop Wettzell." Hochschule für Technik und Wirtschaft Dresden, 2014. https://htw-dresden.qucosa.de/id/qucosa%3A23284.
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Die Verknüpfung von geodätischen Raumtechniken wie GNSS, DORIS, SLR oder VLBI zur Ableitung eines geodätischen Referenzrahmens wie dem ITRF gelingt erst durch sogenannte Kolokationsstationen. Die geometrischen Beziehungen zwischen den betriebenen Raumtechniken sind dabei aus präzisen lokalen Vermessungen abzuleiten. Es wird ein Konzept zur automatisierten Bestimmung des IVS-Referenzpunktes am TWIN Radioteleskop Wettzell vorgestellt. Erste Untersuchungsergebnisse werden präsentiert.
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Moissenet, Didier. "Bacille CDC GROUP IVc-2 : caractérisation, phylogénie, épidémiologie, sensibilité aux antibiotiques." Paris 5, 2006. http://www.theses.fr/2006PA05N05S.
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CDC Group IVc-2 est un bacille à Gram négatif, aérobie strict, mobile grâce à une ciliature péritriche, oxydase et catalase positives et non fermentant. Connu depuis les années 80, il a d'abord été rapproché de Bordetella bronchiseptica puis parfaitement différencié biochimiquement de cette espèce en 1986 par Pickett (87). Sa position taxonomique longtemps indéterminée a été précisée en 1999 (74, 83, 116) et nous y avons contribué (74). Bactérie de l'environnement hydrique (7, 63, 82). .Our study of CDC Group IVc-2 began in 1995 with the report of five bacteriema at Trousseau hospital (APHP). Genotyping with RAPD, used for the first time for this species, showed a single pattern. Pulsed field gel electrophoresis, applied to Trousseau isolates and other French isolates, was unsuccessful since DNA was degraded. These isolates remained undistinguished after genotyping with PCR-ribotyping, PCR-RFLP, IRS-PCR. Surprisingly, all the strains obtained from American (ATCC) and Belgian (LMG) collections were easily distinguished by RAPD. We contributed to the taxonomic study of CDC Group IVc-2 named Ralstonia paucula in. .
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Raman, Rachna. "Inferior vena cava filters in the management of cancer-associated venous thromboembolism: A systematic review." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307442047.
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Yang, Kimberly. "Correlating IVC Measurements with Intravascular Volume Changes at Three Distinct Measurement Sites." Thesis, The University of Arizona, 2014. http://hdl.handle.net/10150/315932.
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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.Bedside ultrasound of the inferior vena cava (IVC) has grown to be an important tool in the assessment and management of critically ill patients. This study endeavors to examine which location along the IVC is most highly correlated with changes in intravascular volume status: (1) the diaphragmatic juncture (DJ) (2) two centimeters caudal to the hepatic vein juncture (2HVJ) or (3) left renal vein juncture (LRVJ). Data was collected in this prospective observational study on patients in the emergency department who were at least 16 years of age, being treated with intravenous fluids (IVF). Measurements of the IVC were recorded at each site during standard inspiratory and expiratory cycles, and again with the patient actively sniffing to decrease intrapleural pressures. IVF was then administered per the patient’s predetermined treatment, and the same six measurements were repeated after completion of fluid bolus. The difference in caval index (dCI) was calculated for all six data sets and correlated with the mL/kg of IVF administered. There was a statistically significant correlation between mL/kg of IVFs administered and dCI at all three sites (DJ: r = 0.354, p value = 0.0002; 2HVJ: r = 0.334, p value = 0.0003; LRVJ: r = 0.192, p value = 0.03). The greatest correlation between amount of fluids administered and dCI was observed along the IVC at the site 2 cm caudal to the juncture of the hepatic veins (2HVJ). This site is also where the largest change in diameter can be appreciated on ultrasound during intravascular volume resuscitation. Our data also suggests that every mL/kg of IVFs administered should change the dCI by 0.86-1.00%. This anticipated change in IVC diameter can be used to gauge a patient’s response to intravascular volume repletion.
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NERY, M. M. R. "Design Gráfico: Análise da Relação Com a Performance da Micro e Pequena Empresa." Universidade Federal do Espírito Santo, 2015. http://repositorio.ufes.br/handle/10/8968.
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Previous issue date: 2015-04-17O design possui um papel central nos negócios, participando de forma crucial no intercambio cultural e econômico da sociedade. Uma das competências do profissional de design gráfico é o desenvolvimento da Identidade Visual Corporativa (IVC). Ela tem como função definir visualmente o perfil de uma empresa, configurando-se, assim, como um composto mercadológico de fundamental importância para diferenciação das organizações, possuindo um importante papel para o crescimento das micro e pequenas empresas (MPEs). O objetivo desta pesquisa é verificar de que forma os gestores de MPEs percebem a atuação do design gráfico sobre a performance do seu negócio, avaliada a partir da sua experiência com a IVC desenvolvida por um profissional de design e aplicada pela empresa em suas atividades. A pesquisa é aplicada, em relação a sua finalidade, e exploratória, quanto ao seu objetivo. Sua condução se deu a partir de pesquisa bibliográfica, entrevista semiestruturada com os gestores das MPEs investigadas e pesquisa documental em materiais fornecidos pelos sujeitos da pesquisa, realizando-se, desta forma, uma triangulação metodológica a fim de contribuir para o exame do fenômeno. Como estratégia de investigação foi utilizado o estudo de casos múltiplos, realizado com 7 (sete) MPEs que haviam incorporado sua IVC há pelo menos 2 (dois) anos, dos setores de comércio e serviço, localizadas nos municípios de Vitória, Vila Velha, Serra ou Cariacica. Os dados coletados foram analisados por meio da Análise de Conteúdo, com base nas etapas descritas por Bardin (1977) e Laville (1999), distribuindo as unidades de análise (frases e parágrafos) nas categorias desenvolvidas: Motivação, Integração da IVC, Gestão da IVC, Relevância da IVC, IVC e Performance e Expressão Visual. A análise utilizou a abordagem quantitativa, realizada por meio da técnica de percentagem, e qualitativa, com maior ênfase na última, onde foram analisadas as categorias e seus elementos, assim como as relações entre elas, buscando extrair os significados construídos. Desta forma, foi possível verificar que a maior parte dos gestores das MPEs investigadas identificam que o design gráfico, por meio da IVC, contribui de forma positiva para a performance do seu negócio, proporcionando diferentes tipos de benefícios, dentre os mais citados foram: Identificação/Reconhecimento, Fortalecimento (solidez, estabilidade, profissionalismo), Novos Clientes, Imagem, Receptividade, Agregação de Valor para a Marca e Diferenciação.
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Schorsch, Isabel. "Die posteriore Intravaginale Schlingeneinlage (IVS) zur Behandlung des Level-1-Defekts der Frau." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-65356.
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Hlásková, Michaela. "Analýza požadavků oceňovacích standardů IVS a jejich aplikace v posudku o ocenění majetku." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-232532.
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The motivation to this master`s thesis is an increasing demand on evaluation of expertise report in conformity with requirements of internationally accepted standards as well as with national legal regulations. This master`s thesis is focused on defining of requirements of International Valuation Standards – IVS. The objective of the introductory study of this thesis is an effort to provide overview of the structure, the history and development of International Valuation Standards – IVS. The introductory study points out that the IVS standard is not stationary one, but shows the importance to keep the continuous track and analyze other possible information sources in connection to it. The main objective is to analyze the principal requirements of International Valuation Standards for expert as a person, expertise activity and required features of expertise report. The gained information is processed on the base of an expertise system approach, where the expertise is interpreted as a structured object with principal features: expertise object, expertise problem, expertise activity, expertise report and expert. Established findings are then analyzed regarding to such interpreted system approach of expertise and applied in the determination of type of approach which an expert should follow in the procedure of making out an expertise report of property valuation. Finally, an example expertise report for valuation of real estate is compiled. Such expertise report could be considered in conformity with national legal regulation as well as with requirements of International Valuation Standards – IVS. The expertise report is a practical example of findings of this master`s thesis.
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Bantelmann, Jürgen. "Die integrativen Verlaufsskalen (IVS-39) : ein Instrument zur Veränderungsmessung und Diagnostik tiefenpsychologisch und integrativ orientierter Psychotherapie /." Münster : Lit, 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=013212300&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Araújo, Paulo Granato de. "Gerenciamento e percepção da identidade visual corporativa (IVC) nas universidades: um estudo de caso na PUC-GO." Universidade do Vale do Rio dos Sinos, 2010. http://www.repositorio.jesuita.org.br/handle/UNISINOS/3724.
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O objetivo desta pesquisa foi o de descrever e entender o fenômeno da identidade visual corporativa (IVC) dentro da PUC-GO na perspectiva de seus gestores e estudantes. Para isso foi utilizado como método de pesquisa o estudo de caso único descritivo, a fim de entender a IVC com mais profundidade. Percebe-se no meio acadêmico e gerencial uma necessidade de se entender esta questão de uma forma mais ampla. Há um interesse crescente das organizações em cuidar da sua imagem e reputação e a identidade visual tem um papel importante neste processo. Este estudo então procurou responder a seguinte pergunta de pesquisa: Como se dá o gerenciamento da IVC da PUC-GO na perspectiva de seus gestores e como a mesma é avaliada pelos estudantes da instituição? Foram coletados dados secundários através de documentos e dados primários que foram entrevistas com cinco gestores e o grupo de foco com sete estudantes. Estes dados foram analisados através da análise de conteúdo contrastando-os com proposições teóricas. A conclusão é de que o órgão gestor principal na gestão da IVC é a DICOM. Apesar do grande esforço e dedicação dos gestores, o processo de gerenciamento é complicado e apresenta dificuldades, o que gerou aplicações problemáticas da IVC na instituição. Há dificuldade no controle do uso da IVC e o reconhecimento da necessidade de otimização do processo. Entre os alunos, houve um sentimento de respeito pela PUC-GO, porém foram detectados problemas no entendimento da idéia central da marca, dentre eles a incompreensão dos elementos do símbolo. Foi detectado na pesquisa que não houve uma associação imediata da identidade visual com os valores da instituição. Surgiram também críticas a respeito da implementação da IVC em diversas aplicações, onde não foi percebida uma padronização desta.
The aim of this research was to describe and understand the phenomenon of corporate visual identity at PUC-GO under the perspective of its managers and students and to achieve this purpose, a descriptive case study approach was used as a methodological tool in order to understand the phenomenon of (CVI) with more depth. It is noted among academics and managers a need to understand this theme with a more holistic approach. There is a growing interest among organizations in taking care of their image and reputation and the visual identity plays an important role in this process. This study tried to answer the following research question: How is the management of PUC-GO held under the perspective of its managers and how is its perception viewed by its students? Secondary data were collected through university internal documents and primary data were collected through interviews with five managers and a focus group with seven students. These data were analysed using content analysis approach facing the studied theory. The findings concluded that the department responsible for the management of the visual identity is DICOM. Despite the great effort and dedication of its managers, it was discovered that the visual identity management process is complicated and presents some difficulties which resulted in some problematic identity applications. There is difficulty in the control and use of the visual identity and the assumption that the process should improve. A great feeling of respect for PUC-GO was recognized among the students, therefore, some problems regarding the understanding of the core idea of the brand were observed. One of these problems was the misunderstanding of the meaning of the symbol. Also, the research found that there was no immediate association with the values of the university and its visual identity. There were also some complaints about the visual identity implementation in various brand touchpoints, where padronization was not perceived.
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Krüger, Philip [Verfasser], Manfred [Akademischer Betreuer] Boltze, and Fritz [Akademischer Betreuer] Busch. "Methodische und konzeptionelle Hinweise zur Entwicklung einer IVS-Rahmenarchitektur für Deutschland / Philip Krüger. Betreuer: Manfred Boltze ; Fritz Busch." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2013. http://d-nb.info/1107772494/34.
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Krüger, Philip Verfasser], Manfred [Akademischer Betreuer] [Boltze, and Fritz [Akademischer Betreuer] Busch. "Methodische und konzeptionelle Hinweise zur Entwicklung einer IVS-Rahmenarchitektur für Deutschland / Philip Krüger. Betreuer: Manfred Boltze ; Fritz Busch." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2013. http://d-nb.info/1107772494/34.
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Hallberg, Henrik. "I.T.R.I.P. Intelligent TrafikRegels och InformationsProgram : Ett säkerhetskoncept." Thesis, Linköping University, Department of Management and Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8707.
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Varje år dör det cirka 500 personer i den svenska trafiken. En strävan att sänka detta olyckstal är uttalat av den svenska regeringen och som effekt av detta har nollvisionen vuxit fram. De allvarliga olyckorna på de svenska vägarna har minskat tack vara kontinuerliga förbättringar av säkerhet i och kring fordon, men på grund av ökad trafikintensitet börjar antalet dödade i trafiken stagnera vid 500 personer per år. För hög fart på dåligt utformade vägsträckor är en bidragande faktor till varför en olycka inträffar och vilka konsekvenser denna olycka resulterar i. I dagens trafiksamhälle tenderar förare att negligera små hastighetsöverträdelser. Tanken med detta examensarbete är att undersöka om ett, för detta arbete framtaget informationssystem, kan få förare mer uppmärksamma på sin hastighet i förhållande till laglig hastighet och därmed eventuellt sänka sin hastighet till laglig nivå
De praktiska testerna genomfördes i hos Avdelningen för Industriell Arbetsvetenskap vid Linköpings Universitet. De simulatortester som genomfördes utfördes av totalt 16 personer som vardera körde tre likadana scenarier med varierande informationsmängd angående gällande laglig hastighet. Försöken jämfördes med varandra och slutsatsen blev att det existerar en skillnad mellan att nyttja den variabla informationen, vilken beskrivs i detta arbete och att inte få någon tilläggsinformation. De mätdata som gavs korrelerade väl med vad testpersonerna ansåg. Det testade systemet var till hjälp, speciellt vid körning på sträckor med en begränsning av 70 km/h.
Resultatet av detta arbete innebär att körning med stödsystem ger en bättre anpassning av hastigheten i förhållande till den gällande lagliga hastigheten i flertalet fall. Försökspersonerna trivdes med systemet och ansåg sig gärna vilja nyttja ett liknande system i sina privata fordon. De hastighetsvariationer som framkommit i simulatorexperimentet bör verifieras mot fältstudier, eftersom resultaten kan vara något missvisande. Dock visar resultaten på att ett hjälpsystem likt det testade systemet mycket troligt skulle kunna sänka de vanliga ofrivilliga fortkörningarna och därmed öka trafiksäkerheten på vägarna. En fortsatt utveckling och forskning kring ett informationssystem likt det undersökta rekommenderas av författaren till detta examensarbete.
Each year approximately 500 persons die in the traffic on the Swedish roads. The Swedish government has an explicit ambition to radically decrease the number of accidents on public roads. This ambition has been labeled the zero vision. The most serious accidents have been reduced in numbers due to continuous improvements of safety in and around vehicles, but due to increased intensity in the traffic, the number of deaths in the Swedish traffic starts to stagnate at nearly 500 persons per year. Too high speed is a strong contributing factor to fatal or lethal consequences of accidents. In today’s traffic drivers also tend to neglect small speed violations. The idea behind this master thesis is to investigate if in-vehicle information system can contribute to drivers’ attention to their speed in relation to speed restrictions.
An experimental investigation was conducted in the driving simulator at Department of Industrial Ergonomics, University of Linköping, Sweden. Sixteen persons participated in the study. Each person drove a scenario three times with different presentation of speed limitation. The results from the test drives corresponded well with the drivers own reflection about the information system. The system had the best effect in areas with speed limits of 70 km/h, when the drivers were unconfident about the legal speed limit.
The performance during the tested speed variations in the simulator should be verified in field studies, since data collected in the current simulator setting might be compromised due to a bias in estimations of own speed. However, test results indicate that the tested system should decrease the amount of involuntary speeding and accordingly increase the road safety. Further development and research concerning a system similar to the information system developed during this degree project is recommended by the author.
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Skoruppa, Stefan [Verfasser], and Alfons [Akademischer Betreuer] Hofstetter. "Die vordere und hintere intravaginale Schlingenplastik (anteriore und posteriore IVS) in der Behandlung der Harninkontinenz / Stefan Skoruppa. Betreuer: Alfons Hofstetter." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1105373878/34.
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Nery, Maria Martins Rebolças. "Design gráfico : análise da relação com a performance da micro e pequena empresa." Universidade Federal do Espírito Santo, 2015. http://repositorio.ufes.br/handle/10/8968.
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Previous issue date: 2015-04-17O design possui um papel central nos negócios, participando de forma crucial no intercambio cultural e econômico da sociedade. Uma das competências do profissional de design gráfico é o desenvolvimento da Identidade Visual Corporativa (IVC). Ela tem como função definir visualmente o perfil de uma empresa, configurando-se, assim, como um composto mercadológico de fundamental importância para diferenciação das organizações, possuindo um importante papel para o crescimento das micro e pequenas empresas (MPEs). O objetivo desta pesquisa é verificar de que forma os gestores de MPEs percebem a atuação do design gráfico sobre a performance do seu negócio, avaliada a partir da sua experiência com a IVC desenvolvida por um profissional de design e aplicada pela empresa em suas atividades. A pesquisa é aplicada, em relação a sua finalidade, e exploratória, quanto ao seu objetivo. Sua condução se deu a partir de pesquisa bibliográfica, entrevista semiestruturada com os gestores das MPEs investigadas e pesquisa documental em materiais fornecidos pelos sujeitos da pesquisa, realizando-se, desta forma, uma triangulação metodológica a fim de contribuir para o exame do fenômeno. Como estratégia de investigação foi utilizado o estudo de casos múltiplos, realizado com 7 (sete) MPEs que haviam incorporado sua IVC há pelo menos 2 (dois) anos, dos setores de comércio e serviço, localizadas nos municípios de Vitória, Vila Velha, Serra ou Cariacica. Os dados coletados foram analisados por meio da Análise de Conteúdo, com base nas etapas descritas por Bardin (1977) e Laville (1999), distribuindo as unidades de análise (frases e parágrafos) nas categorias desenvolvidas: Motivação, Integração da IVC, Gestão da IVC, Relevância da IVC, IVC e Performance e Expressão Visual. A análise utilizou a abordagem quantitativa, realizada por meio da técnica de percentagem, e qualitativa, com maior ênfase na última, onde foram analisadas as categorias e seus elementos, assim como as relações entre elas, buscando extrair os significados construídos. Desta forma, foi possível verificar que a maior parte dos gestores das MPEs investigadas identificam que o design gráfico, por meio da IVC, contribui de forma positiva para a performance do seu negócio, proporcionando diferentes tipos de benefícios, dentre os mais citados foram: Identificação/Reconhecimento, Fortalecimento (solidez, estabilidade, profissionalismo), Novos Clientes, Imagem, Receptividade, Agregação de Valor para a Marca e Diferenciação.
Design has a central role in business, participating in a crucial way in the cultural and economic interchange of society. One of the competences of the graphic design professional is the development of Corporate Visual Identity (CVI). It has the function to visually define a company profile, setting up, thus, as a marketing compound of fundamental importance for the differentiation of organizations, having an important role in the growth of micro and small enterprises (MSEs). The aim of this research is to verify how MSEs managers perceive the graphic design action on the performance of your company, evaluated from their experience with the IVC developed by a professional designer and applied by the company in its activities. The research is applied in relation to its purpose, and exploratory, as your goal. Its conduction was made from bibliographic research, semi-structured interviews with the research subjects and documentary research on materials provided by the managers of the investigated SMEs, performing, thereby, a methodological triangulation in order to contribute to the examination of the phenomenon. As a research strategy was used the multiple case study, conducted with 7 (seven) MSEs that had incorporated their CVI for at least 2 (two) years, from commerce and service sectors, located in the cities of Vitoria, Vila Velha, Serra or Cariacica. The collected data were analyzed using Content Analysis, based on the steps described by Bardin (1977) and Laville (1999), distributing the units of analysis (sentences and paragraphs) in the developed categories: Motivation, Integration of CVI, Management CVI, Relevance of CVI, CVI and Performance and Visual Expression. The analysis used a quantitative approach, carried out through the percentage technique, and qualitative, with greater emphasis on the latter, where were analyzed the categories and its elements, and the relationships between them, trying to extract the constructed meanings. This way, it was possible to verify that most of the managers of the investigated MSEs identify that graphic design, through the CVI, contributes positively to the performance of your business, providing different kinds of benefits, among the most cited were: Identification / Recognition, Strengthening (solidity stability, professionalism), New Customers, Image, Receptiveness, Adding Value for the Brand and Differentiation.
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Moll, Christine. "PCR Untersuchung von Abluftstäuben auf murine Noroviren und murine Hepatitis Viren zur Verbesserung des Hygienemonotorings von SPF Mäusen in IVC Haltung." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-149055.
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Hussain, Raza, Alay Mansurov, Kanishka Chakraborty, and Alisa Vasileva. "Absence of Infrarenal inferior vena cava Leading to Deep Venous Thrombosis and Incidental Finding of Nutcracker Syndrome." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/asrf/2020/presentations/17.
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Introduction: Inferior vena cava (IVC) malformations are extremely rare. Their impact with additional risk factors has not been well studied. Here, we present a case of a young female with absent IVC. She presented with an extensive left lower extremity (LLE) deep venous thrombosis (DVT) after starting oral contraceptives.
Case: A 21-year-old female with no past medical history presented with progressively worsening back pain and LLE edema. Her only medication was combined oral contraceptive (OCP) which was started 4 months ago. Physical exam was significant for blue discoloration of her LLE extending from foot to thigh. The ultrasound showed multiple thrombi within the left common and deep femoral veins, left popliteal vein and left peroneal vein. The abdominal computerized tomography revealed the absence of an infrarenal IVC with collateral azygous, hemiazygous and prominent left gonadal veins. Occlusion by the thrombi extended from the left femoral vein to the left iliac vein. Some extension was noted into the right common iliac vein. She was treated with a catheter directed tissue plasminogen activator (tPA) infusion into the left iliac vein followed by continuous heparin infusion. Hypercoagulable testing was negative. While on heparin, she developed asymptomatic gross hematuria. CT urogram showed a significant dilation of the left gonadal vein, a large vein along the left psoas muscle draining into the left renal vein, and a mild enlargement of right gonadal vein. The urine analysis was negative for bacterial infection; but it contained a numerous amount of red blood cells and protein. Once the hematuria had resolved, she was discharged on apixaban. Her OCP was discontinued.
Discussion: There have been several case reports describing IVC abnormalities associated with DVT. In our case, DVT was likely provoked by usage of OCP. Current guidelines would require provoked DVTs to be treat for at least 3-12 months with anticoagulation therapy. Case reports of IVC malformations illustrated that these patients are at high risk for DVT at baseline. Hence the underlying abnormality still poses a lifetime risk. Also, with abnormal venous vasculature, gross hematuria, proteinuria and the lack of other causes, we suspect underlying Nutcracker syndrome (NS). Her pelvic abdominal pain can also be attributed to pelvic congestion syndrome, which is commonly associated with NS.
Conclusion: There are several questions that arise from this case including: selecting a type of contraceptive method; safety of direct thrombin inhibitors in patients with NS; indefinite direct thrombin inhibitors in young patients. Unfortunately, due to the rarity of this condition, no set guidelines are available on how to manage these individuals.
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Moll, Christine [Verfasser], and Bernhard [Akademischer Betreuer] Aigner. "PCR Untersuchung von Abluftstäuben auf murine Noroviren und murine Hepatitis Viren zur Verbesserung des Hygienemonotorings von SPF Mäusen in IVC Haltung / Christine Moll. Betreuer: Bernhard Aigner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/1026846773/34.
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Del, Carpio Torres Miguel Ángel. "Resultados post operatorios por tratamiento quirúrgico de prolapso genital del compartimiento medio con implante de Malla-IVS posterior, en el Hospital Dos de Mayo 2011 – 2012." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/8999.
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El documento digital no refiere asesorPublicación a texto completo no autorizada por el autor
Determina los resultados post operatorios por tratamiento quirúrgico de prolapso genital del compartimiento medio con implante de Malla-IVS posterior, en el Hospital Dos de Mayo 2011 - 2012. Es un estudio observacional, descriptivo, retrospectivo. Se estudió a 43 pacientes con tratamiento quirúrgico de prolapso genital del compartimiento medio con implante de Malla-IVS posterior. Para describir las variables numéricas se utilizó medida de tendencia central y de dispersión, para las variables cualitativas se usó frecuencias absolutas y relativas. En el análisis bivariado se utilizó la prueba Chi-cuadrado con un nivel de confianza del 95%. La edad de las pacientes estuvo comprendida entre 35 a 85 años con una media de 56.7 años, el estado civil más frecuente fue “casada” (53.5%), el nivel de educación en su mayoría fue secundaria (51.2%). En las características obstétricas se observó mayor porcentaje de pacientes con gesta > a 3 y > a 3 partos. Respecto a la seguridad del implante de malla IVS posterior solo se observó hematoma vulvar en el 4.7% de las pacientes mas no se observó otras complicaciones. En la evaluación de la actividad sexual; ninguna paciente presentó disfunción sexual, en el 81.4% se resolvió la dispareunia y el 18.6% tuvo dispareunia persistente. Los resultados que evaluaron mejora de la alteración de la micción y evacuación se observó en el 79.1% incontinencia urinaria de esfuerzo “resuelta”, la urgencia urinaria se resolvió en el 93% y solo se encontró un caso de incontinencia fecal. La duración del tiempo quirúrgico fue < a 2 horas en el 65.1% y > a 2 horas en 34,9%, donde la estancia hospitalaria fue de 2 a 4 días en mayor proporción (51,2%). Además de realizar la técnica IVS posterior algunas pacientes requirieron técnicas de corrección adicionales como Nazta TC (23%), Sleep TOT (7%), Sleep TOT y Peregre (7%); y al relacionar dichas técnicas con la frecuencia de complicaciones o tasa de cura del paciente no se observó relación significativa entre dichas variables. Al evaluar la eficacia de la Malla polipropileno macroporo monofilamento “malla casera” en la técnica IVS posterior se logró la cura del prolapso genital en el 90.7% de las pacientes. Se concluye el implante de la malla “casera” mediante la técnica IVS posterior es eficaz en la corrección del prolapso genital, debido a la mayor frecuencia de cura y escasas complicaciones.
Trabajo académico
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Iqbal, Zeeshan. "Self-Organizing Wireless Sensor Networks For Inter-Vehicle Communication." Thesis, Halmstad University, School of Information Science, Computer and Electrical Engineering (IDE), 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-230.
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Now a day, one of the most attractive research topics in the area of Intelligent Traffic Control is
Inter-vehicle communication (V2V communication). In V2V communication, a vehicle can
communicate to its neighbouring vehicles even in the absence of a central Base Station. The
concept of this direct communication is to send vehicle safety messages one-to-one or one-to-
many vehicles via wireless connection. Such messages are usually short in length and have very
short lifetime in which they must reach the destination. The Inter-vehicle communication system
is an ad-hoc network with high mobility and changing number of nodes, where mobile nodes
dynamically create temporary sensor networks and transferring messages from one network to
others by using multiple hops due to limitation of short range.
The goal of the project is to investigate some basic research questions in order to organize such
sensor networks and at the same time highlight the appropriate routing protocol that support
mobile ad hoc networks in an efficient and reliable manner.
In our investigation, we have answered the technical issues in order to construct a V2V
communication system. We have also studied some mobile ad hoc network routing protocols in
detail and then selected the DSR (Dynamic Source Routing) for our V2V communication and
then simulated it according to our system requirements. We are quite satisfied by the result of
DSR, but at the same time much more work is required to come up with an absolute application
for the end user.
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Nery, Maria Martins Rebouças. "Design gráfico : análise da relação com a performance da micro e pequena empresa." reponame:Repositório Institucional da UFES, 2015. http://repositorio.ufes.br/handle/10/1438.
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O design possui um papel central nos negócios, participando de forma crucial no intercambio cultural e econômico da sociedade. Uma das competências do profissional de design gráfico é o desenvolvimento da Identidade Visual Corporativa (IVC). Ela tem como função definir visualmente o perfil de uma empresa, configurando-se, assim, como um composto mercadológico de fundamental importância para diferenciação das organizações, possuindo um importante papel para o crescimento das micro e pequenas empresas (MPEs). O objetivo desta pesquisa é verificar de que forma os gestores de MPEs percebem a atuação do design gráfico sobre a performance do seu negócio, avaliada a partir da sua experiência com a IVC desenvolvida por um profissional de design e aplicada pela empresa em suas atividades. A pesquisa é aplicada, em relação a sua finalidade, e exploratória, quanto ao seu objetivo. Sua condução se deu a partir de pesquisa bibliográfica, entrevista semiestruturada com os gestores das MPEs investigadas e pesquisa documental em materiais fornecidos pelos sujeitos da pesquisa, realizando-se, desta forma, uma triangulação metodológica a fim de contribuir para o exame do fenômeno. Como estratégia de investigação foi utilizado o estudo de casos múltiplos, realizado com 7 (sete) MPEs que haviam incorporado sua IVC há pelo menos 2 (dois) anos, dos setores de comércio e serviço, localizadas nos municípios de Vitória, Vila Velha, Serra ou Cariacica. Os dados coletados foram analisados por meio da Análise de Conteúdo, com base nas etapas descritas por Bardin (1977) e Laville (1999), distribuindo as unidades de análise (frases e parágrafos) nas categorias desenvolvidas: Motivação, Integração da IVC, Gestão da IVC, Relevância da IVC, IVC e Performance e Expressão Visual. A análise utilizou a abordagem quantitativa, realizada por meio da técnica de percentagem, e qualitativa, com maior ênfase na última, onde foram analisadas as categorias e seus elementos, assim como as relações entre elas, buscando extrair os significados construídos. Desta forma, foi possível verificar que a maior parte dos gestores das MPEs investigadas identificam que o design gráfico, por meio da IVC, contribui de forma positiva para a performance do seu negócio, proporcionando diferentes tipos de benefícios, dentre os mais citados foram: Identificação/Reconhecimento, Fortalecimento (solidez, estabilidade, profissionalismo), Novos Clientes, Imagem, Receptividade, Agregação de Valor para a Marca e Diferenciação.
Design has a central role in business, participating in a crucial way in the cultural and economic interchange of society. One of the competences of the graphic design professional is the development of Corporate Visual Identity (CVI). It has the function to visually define a company profile, setting up, thus, as a marketing compound of fundamental importance for the differentiation of organizations, having an important role in the growth of micro and small enterprises (MSEs). The aim of this research is to verify how MSEs managers perceive the graphic design action on the performance of your company, evaluated from their experience with the IVC developed by a professional designer and applied by the company in its activities. The research is applied in relation to its purpose, and exploratory, as your goal. Its conduction was made from bibliographic research, semi-structured interviews with the research subjects and documentary research on materials provided by the managers of the investigated SMEs, performing, thereby, a methodological triangulation in order to contribute to the examination of the phenomenon. As a research strategy was used the multiple case study, conducted with 7 (seven) MSEs that had incorporated their CVI for at least 2 (two) years, from commerce and service sectors, located in the cities of Vitoria, Vila Velha, Serra or Cariacica. The collected data were analyzed using Content Analysis, based on the steps described by Bardin (1977) and Laville (1999), distributing the units of analysis (sentences and paragraphs) in the developed categories: Motivation, Integration of CVI, Management CVI, Relevance of CVI, CVI and Performance and Visual Expression. The analysis used a quantitative approach, carried out through the percentage technique, and qualitative, with greater emphasis on the latter, where were analyzed the categories and its elements, and the relationships between them, trying to extract the constructed meanings. This way, it was possible to verify that most of the managers of the investigated MSEs identify that graphic design, through the CVI, contributes positively to the performance of your business, providing different kinds of benefits, among the most cited were: Identification / Recognition, Strengthening (solidity stability, professionalism), New Customers, Image, Receptiveness, Adding Value for the Brand and Differentiation.
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Sagokon, Evgeniya. "Oceňování a vykazování nehmotných aktiv při akvizici v rozsahu IFRS." Master's thesis, Vysoká škola ekonomická v Praze, 2015. http://www.nusl.cz/ntk/nusl-264648.
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This master thesis deals with specifics of valuation, recognition and reporting of intangible assets that were acquired as a business combination under IFRS. This thesis is also devoted to specifics of intangible assets which indicate importance and difficulty of its standardization in accounting. The aim of the master thesis is to combine valuation and accounting standards for intangible assets with emphasis on acquisition process. Practical part is here to show how definitely companies valuate, measure and recognize intangible assets acquired in a business combination.
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Song, Xiaohu. "Descripteurs couleur locaux invariants aux conditions d'acquisition." Phd thesis, Université Jean Monnet - Saint-Etienne, 2011. http://tel.archives-ouvertes.fr/tel-00719349.
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La mise au point de descripteurs locaux discriminants est aujourd'hui une priorité dans de nombreuses applications comme la reconnaissance d'objets, le suivi d'objets, la reconstruction 3D ou l'estimation de mouvement. La problématique réside dans le fait que ces descripteurs doivent être invariants aux conditions d'acquisition tout en conservant un pouvoir discriminant important. Dans ce contexte, nous nous sommes intéressés à l'invariance des descripteurs locaux de la littérature. Nous les avons notamment catégorisés en fonction des hypothèses sur lesquelles repose leur invariance. Ensuite, nous avons proposé des descripteurs locaux qui exploitent l'information de couleur dans les images. Nous avons montré que cette information peut être très pertinente lorsqu'elle est combinée à une information spatiale, à condition que son degré d'invariance soit contrôlé et adapté aux applications considérées. Ainsi, nous avons proposé un ensemble de descripteurs locaux couleur avec des degrés d'invariance différents. Ainsi, nous introduisons tout d'abord deux nouveaux descripteurs qui caractérisent les distributions spatiales des couleurs dans les régions analysées. L'idée originale consiste à appliquer des transformations affines entre les coordonnées spatiales des pixels et leurs coordonnées couleur. En effet, chaque pixel étant caractérisé par 5 valeurs, 2 coordonnées spatiales xy dans l'image et 3 composantes couleur RVB, nous proposons de rechercher une transformation affine qui permet de transformer les coordonnées xy de tous les pixels de la région concernée en coordonnées RVB de ces pixels. Nous montrons que l'application de cette transformation aux coordonnées xy fournit des coordonnées dans l'espace RVB qui a un double avantage. D'une part, les coordonnées d'un seul pixel dépendent à la fois de toutes les couleurs présentes dans la région mais aussi de leur répartition spatiale. Quelques coordonnées permettent donc de résumer efficacement le contenu de la région. D'autre part, ces coordonnées présente une invariance totale à toute transformation affine appliquée dans l'espace image 2D(invariance géométrique) et comme elles sont homogènes à des coordonnées couleur, nous pouvons leur procurer une invariance photométrique en leur appliquant des transformations affines particulières. Nous montrons que le degré d'invariance peut être contrôlé en fonction des besoins de l'application. Ces coordonnées nous permettent de définir le descripteur IVC (Image Vers Couleur). De manière similaire, nous évaluons une transformation affine de l'espace couleur à l'espace image et appliquons cette transformation aux coordonnées couleur. Les coordonnées obtenues par cette transformation sont invariantes à toute transformation affine appliquée dans l'espace couleur, elles présentent donc un degré d'invariance élevé aux variations photométriques. Ces coordonnées nous permettent de constituer le descripteur CVI (Couleur Vers Image). Nous montrons que ces deux descripteurs fournissent de très bons résultats dans le cadre de la reconnaissance d'objet et présentent une telle complémentarité que le descripteur obtenu par concaténation de IVC et CVI fournit de meilleurs résultats que la plupart des descripteurs couleur parus dans la littérature. Ensuite, nous proposons un descripteur qui présente un degré d'invariance plus élevé que les deux précédents puisqu'il n'est pas sensible aux transformations non-linéaires des couleurs modélisées par des fonctions croissantes appliquées indépendamment sur chaque composante couleur. Pour cela, nous exploitons les mesures de rang des pixels dans les images. De plus, nous utilisons les corrélations entre mesures de rang obtenues pour différentes composantes couleur. Ceci nous a permis de proposer un descripteur lui aussi très compact qui présente un degré d'invariance photométrique assez élevé. Enfin, nous abordons le problème de la caractérisation locale d'images par auto-similarités
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Myhrberg, Jakob, and Gustav Raab-Obermayr. "Koldioxidreducering av en bergtäkts fordonsflotta." Thesis, Linnéuniversitetet, Institutionen för byggteknik (BY), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-85632.
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Ballast som byggnadsmaterial är viktigt för att utveckla vårt samhälle då det bland annat används som beståndsdel i asfalt och betong. Det är därför viktigt att bergkross som bryts i bergtäkter har en fungerande produktion för att möta efterfrågan men också för att Sverige ska kunna nå målet att vara klimatneutralt 2045. Syftet med arbetet är att minska miljöpåverkan i en bergtäkt från de interna transporterna och målet är att ta fram åtgärder för att uppnå detta. De metoder som har använts är litteraturstudier, beräkningar, simuleringar och intervjuer. Genom beräkningarna kunde ett resultat i detta arbete visa att en reducering med 88 % av koldioxidutsläpp kan göras genom att använda biodrivmedlet HVO Diesel 100. Det har med hjälp av intervjuer och litteraturstudier dessutom dragits en slutsats att framtidens bergtäkter antas producera bergkross med elektriska autonoma maskiner.Ballast as a building material is important for developing our society as it’s used as a component in asphalt and concrete. Hence it is important that crushed rock extracted from a quarry have a functioning production to meet the demand that exists, but also because Sweden should be able to reach the goal of being climate neutral 2045. The purpose of this study is to reduce the environmental impact in a quarry from the internal transports and the aim is to bring out suggestions to achieve this. The methods that have been used are literature studies, calculations, simulations and interviews. Through the calculations, a result in this work showed that a reduction of 88 % of carbon dioxide emissions can be made by using the biofuel HVO Diesel 100. In addition, with the help of interviews and literature studies, conclusions have been drawn that the future quarries are believed to produce crushed rock with electric autonomous machines.
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Doležalová, Lucie. "Nedostatky ve znaleckých posudcích s doporučením na jejich odstranění." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-77861.
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The content of this work is the analysis of expert opinions on the valuation of the business or its parts in several respects. In the introduction it is mentioned adjustment of valuation by Czech methodology ZNAL, International Valuation Standards IVS and European Valuation Standards EVS. Furthermore, it is carried out the comparison of these methodologies, including the German Standard IDW S1, according to some criteria. The analytical section is dedicated to the analysis of expert opinions, to assess their level of processing, and to point out some weaknesses or strengths. The conclusion is a quantitative summary of the results of analysis of expertise, as well as pointing out the most common shortcomings and proposals for their elimination.
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Myrén, Nathalie. "DET REDUCERADE AKTIEKAPITALKRAVET UR ETT BORGENÄRSSKYDDSPERSPEKTIV : En svensk, dansk och finsk studie." Thesis, Karlstads universitet, Handelshögskolan (from 2013), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-77929.
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Det aktiebolagsrättsliga kapitalkravet har från det att kravet blev lagstadgat syftat till att säkerställa att det alltid föreligger ett ekonomiskt utrymme mellan aktiebolagets tillgångar och skulder. Därtill ska kravet fungera som en seriositetsspärr och borgenärsskydd. Kravet på en lägsta aktiekapitalgräns har historiskt sett utgjort ett betydande skydd för borgenärerna. Aktiekapitalkravet har betraktats som nödvändigt för borgenärerna bl.a. av den anledning att säkerställa att det finns en tillräcklig ekonomisk marginal som ska svara för bolagets förpliktelser. I denna uppsats utreds aktiekapitalet och det bakomliggande syftet att tillförsäkra borgenärerna säkerhet såväl det nationella kravet som två andra nordiska rättsordningars krav.Kapitalkraven i Europa har genomgått många reformeringar, majoriteten av länderna har reducerat deras kapitalkrav för privata aktiebolag och vissa länder har t.o.m. valt att slopa kapitalkravet helt. Danmark var ett av de länder där möjligheten fanns att bilda en viss bolagsform med begränsat personligt ansvar utan kapitalkrav, något som senare visade sig ge oönskade effekter och således avskaffades bolagsformen år 2019. Finland däremot gick åt motsatt håll och valde istället att slopa sitt kapitalkrav för privata bolag år 2019. Året därpå, år 2020, reformerades det svenska kravet och sänktes ytterligare. Kapitalkravet har och är fokus för förändring och dess framtida utveckling ser ut att gå mot allt fler reducerade kapitalkrav internationellt.Med tanke på de tre nordiska ländernas senaste förändringar av kapitalkravet angrips kravet och dess syfte att skydda borgenärerna genom en komparativ metod. Utöver den komparativa metoden analyseras det svenska aktiekapitalkravet genom en rättsdogmatisk metod. Härigenom ligger danska, finska och svenska rättskällor som grund för uppsatsens slutsatser.Uppsatsens slutsats är bl.a. att aktiekapitalkravet inte längre ses som ett borgenärsskydd utan incitamentet att göra associationsformen mer tillgänglig torde ersätta syftet att skydda borgenärerna. Kravets borgenärsskyddssyfte har blivit kraftlöst i takt med de successiva sänkningarna som gjorts under åren. Härigenom påverkas inte borgenärerna längre av reducerade kapitalkrav likt den sänkning som gjordes år 2020. Ytterligare slutsatser som görs i uppsatsen är att de nordiska länderna delar liknande teorigrunder vad gäller kapitalkravet som borgenärsskydd. Utredningen påvisar även hur de nordiska länderna haft liknande motiv för deras inbördes förändringar kring kapitalkravet under det senaste året.
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Feltrin, Cristiano. "Avaliação de sistemas de cultivo in vitro em micropoços para embriões bovinos produzidos por handmade cloning (HMC)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/24994.
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Sistemas de produção in vitro de embriões mamíferos muitas vezes requerem que o cultivo embrionário seja realizado de forma individualizada. Entretanto, os resultados obtidos com o cultivo in vitro (CIV) individual são inconstantes e, por vezes, inferiores ao CIV em grupo. Entre os sistemas que requerem o CIV individual, a técnica de handmade cloning (HMC) se destaca por produzir embriões sem zona pelúcida que não podem ser cultivados agrupados em protocolos convencionais de CIV. O objetivo deste experimento foi determinar as taxas de desenvolvimento in vitro e in vivo de embriões bovinos clonados pela técnica de HMC e submetidos a três diferentes sistemas de CIV em micropoços (Well of the well – WOW), sendo um industrial, confeccionado em polidimetilsiloxano (PDMS), que visou à padronização da configuração do sistema de CIV. Após 11 replicações, de 3.876 complexos cumuli-oócito bovinos maturados in vitro, 3.437 (88,6%) oócitos apresentaram a extrusão do 1º corpúsculo polar. Após a digestão da zona pelúcida, 2.992 estruturas foram bisseccionadas manualmente, com a produção de 2.288 hemi-citoplastos. Reconstruiram-se 1.011 embriões pela adesão de dois hemi-citoplastos a uma célula somática (célula-tronco mesenquimal bovina de uma fêmea adulta da raça Nelore), dos quais 751 (74,2%) embriões fusionaram após eletrofusão, sendo 715 ativados quimicamente. Os embriões clonados (n=705) foram então alocados aleatoriamente em três grupos experimentais para o CIV: Grupo 1 (G1) – micropoço modificado (WOW-modificado, FELTRIN et al., 2006a); Grupo 2 (G2) – micropoço convencional (WOW-convencional , VATJA et al., 2000); e Grupo 3 (G3) – micropoço – PDMS (WOW-PDMS) . Como grupo controle (FIV, Grupo 4, G4), 594 oócitos foram colocados em maturação, fecundação e cultivo in vitro, em paralelo aos grupos clonados. Os resultados das taxas de clivagem no Dia 2, de blastocisto no Dia 7 e de prenhez no Dia 30 de desenvolvimento foram analisados pelo teste do χ2 com nível de significância de 5%. Não houve diferença significativa quanto à taxa de clivagem nos diferentes grupos. Entretanto, a taxa de blastocisto (BL) no G1 (99/239; 41,4%) foi significativamente superior à observada no G2 (72/232; 31,0%) e no G3 (68/234; 29,1%), sendo estas últimas semelhantes entre si. A taxa de BL do grupo controle (315/594; 53,0%) foi superior aos três grupos experimentais. Finalmente, o desenvolvimento in vivo até o Dia 30 de prenhez não diferiu entre os grupos G1 (7/15; 46,7%), G2 (7/13; 53,9%) e G3 (6/16; 50,0%). O sistema em micropoço modificado promoveu melhores condições de CIV a embriões clonados por HMC, traduzido por maiores taxas de BL, não se refletindo, entretanto, em diferenças no desenvolvimento in vivo subseqüente à transferência para fêmeas receptoras.In vitro production systems for mammalian embryos quite often require embryos to be cultured individually. However, results obtained after individual embryo in vitro culture (IVC) are frequently inconsistent and inferior to IVC in groups. The Handmade Cloning (HMC) procedure is among the systems that require individual IVC, since zona-free embryos cannot be grouped for culture by standard IVC protocols. The aim of this study was to evaluate the in vitro and in vivo development of bovine embryos cloned by HMC, after the IVC in three distinct microwell arrangements, including an industrial chip, manufactured in polydimethylsiloxane (PDMS), which aimed to standardize the pattern of the IVC system. After 11 replications, 3,437 (88.6%) oocytes were selected based on the extrusion of the first polar body, out of 3,876 in vitro-matured bovine cumuli-oocyte complexes. Following zona pellucida digestion, 2,992 structures were manually bisected, generating 2,288 hemi-cytoplasts. A total of 1,011 embryos were reconstructed by the adhesion of two hemi-cytoplasts to a somatic cell (bovine mesenchymal stem cells from an adult Nelore female), with 751 fusing (74.2%) following electrofusion, and 715 being chemically activated. Cloned embryos (n=705) were then randomly allocated to one of three IVC experimental groups: Group 1 (G1) – modified microwells (FELTRIN et al., 2006a); Group 2 (G2) – conventional microwells (VATJA et al., 2000); and Group 3 (G3) – microwells in PDMS. As control group (IVF, Group 4, G4), 594 oocytes were in vitro-matured, fertilized and cultured in parallel to the cloned groups. Cleavage, blastocyst and pregnancy rates evaluated on Days 2, 7 and 30 of development were analyzed by the χ2 test, for a significance level of 5%. No differences in cleavage rates were observed between groups. However, blastocyst rates in G1 (99/239; 41.4%) were significantly higher than in G2 (72/232; 31.0%) and in G3 (68/234; 29.1%), which did not differ between one another. Blastocyst rates in the IVF control group (315/594; 53.0%) were in turn higher than in all cloned experimental groups. Finally, in vivo development to Day 30 of pregnancy was not different between G1 (7/15; 46.7%), G2 (7/13; 53.9%) and G3 (6/16; 50.0%). In summary, the modified microwell system promoted superior development to the blastocyst stage than both the conventional and the DMPS-based microwell systems, with no impact on the subsequent in vivo development after transfer to female recipients.
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Meulemans, Laetitia. "Caractérisation fonctionnelle de variations splicéogéniques à l'origine d'anomalies d'épissage en phase dans des gènes de prédisposition aux cancers : implications en génétique médicale Skipping nonsense to maintain function : the paradigm of BRCA2 Exon 12 Functional characterization of MSH2 variants resulting into in-frame splicing alterations." Thesis, Normandie, 2021. http://www.theses.fr/2021NORMR008.
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Aujourd’hui, le défi majeur en génétique médicale est l’interprétation clinique des variations détectées dans le génome des patients. Dans un contexte de maladie monogénique, l’identification de la variation pathogène permet d’optimiser la prise en charge des patients et de leurs apparentés. Les variations non-sens ainsi que celles localisées au niveau des sites canoniques d’épissage (IVS±1/2) sont généralement considérées causales. Toutefois, il est possible que certaines d’entre elles induisent des anomalies d’épissage en phase permettant potentiellement la production d’une protéine fonctionnelle. Afin de tester cette hypothèse, nous avons choisi comme modèles d’étude deux gènes majeurs de prédisposition aux cancers : BRCA2, pour le syndrome sein-ovaire et MSH2, pour le syndrome de Lynch. Des approches expérimentales complémentaires ont été mises à profit afin de caractériser l’impact de ce type de variations non seulement au niveau de l’épissage mais également au niveau de la protéine. Notre étude portant sur des variations de BRCA2 a démontré que certaines variations IVS±1/2 et non-sens (i) induisent un saut en phase de l’exon 12 du fait de l’altération de sites d’épissage ou d’éléments de régulation et (ii) sont de ce fait responsables du maintien de l’activité BRCA2, tout en étant hypomorphes. Ces travaux montrent, pour la première fois dans un gène de prédisposition au cancer, que certaines variations présumées nulles peuvent contourner la perte totale de fonction du fait de leur impact sur l’épissage. Nos données remettent ainsi en question le caractère pathogène de ces variations. Dans le cadre de notre étude portant sur des variations IVS±1/2 de MSH2, nous avons caractérisé trois biotypes d’anomalies d’épissage en phase : (i) des sauts d’exon, (ii) des délétions de portions exoniques et (iii) des rétentions introniques, avec pour conséquence au niveau protéique des délétions ou insertions de plus ou moins grande taille dans différents domaines fonctionnels. Toutes les isoformes protéiques MSH2 résultant de ces variations splicéogéniques se sont avérées inactives, confirmant ainsi leur caractère pathogène. L’ensemble de ces travaux souligne l’importance d’exercer une certaine prudence dans l’interprétation des variations considérées a priori pathogènes mais susceptibles de générer des anomalies d’épissage en phase. Dans ce contexte, la combinaison d’approches expérimentales complémentaires pour appréhender l’impact biologique au niveau de l’ARN et de la protéine est essentielle pour une interprétation fiable de ce type de variations. Ces données mettent également en exergue la problématique de l’interprétation clinique des variations hypomorphes dans les gènes de prédisposition aux cancersToday, the major challenge in medical genetics is the clinical interpretation of nucleotide variants detected in a patient’s genome. In the context of a monogenic disease, the identification of the pathogenic variant allows the optimization of the medical care of patients and their relatives. Nonsense variations as well as those located at the canonical splice sites (IVS±1/2) are generally considered pathogenic. However, it is possible that a fraction of them induce in-frame splicing anomalies that can potentially result in the production of a functional protein. To test this hypothesis, we used as model systems two major cancer-predisposition genes: BRCA2, implicated in hereditary breast and ovarian cancer syndrome and MSH2, involved in Lynch syndrome. We took advantage of complementary experimental approaches to characterize the impact of this type of variants not only in RNA splicing but also at the protein level. Our study on BRCA2 demonstrated that a subset of IVS±1/2 and nonsense variants (i) induce in-frame skipping of exon 12 via the modification of splice sites or of splicing regulatory elements and (ii) are able to maintain BRCA2 activity though being hypomorphic. These data provide the first evidence, in a cancer-predisposition gene, that certain presumed null variants can bypass total loss of function due to their impact on splicing. Thus our findings call into question the pathogenic nature of these variants. In our study on MSH2 IVS±1/2 variants, we characterized three biotypes of in-frame splicing defects responsible for deletions or insertions at the protein level in different MSH2 functional domains: (i) exon skipping, (ii) deletions of exonic portions and (iii) intron retentions. All the MSH2 protein isoforms resulting from these spliceogenic variants were found to be inactive, thus confirming their pathogenic classification. Altogether, our findings highlight the need to exercise caution in the interpretation of putative pathogenic variants susceptible to induce in-frame splicing modifications. In this context, the combination of complementary experimental approaches assessing the biological impact at the RNA and protein level is essential for a reliable interpretation of this type of variants. Furthermore, our results stress the problem of the clinical interpretation of hypomorphic variants in cancer-predisposition genes
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Banzetová, Diana. "Způsoby ocenění nemovitostí ve Velké Británii se zaměřením na rodinné domy." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-233088.
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This thesis deals with residential real estate market in the Great Britain and its development. The thesis describes all evalution methods used in the Great Britain, it also describes the current state of the property market, expert work and in the end are described in detail the methods used for the valuation of the house. In thesis attachment is an exemplar of the evalution report for a house in the Great Britain according to the standards and the methodologies used by the evaluation experts in the United Kingdom.
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Tian, Bin. "Data dissemination protocols and mobility model for VANETs." Thesis, Clermont-Ferrand 2, 2016. http://www.theses.fr/2016CLF22739/document.
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Pendant les deux dernières décennies, les technologies de réseaux ad-hoc de véhicules (VANETs : Vehicular Ad-Hoc Networks) ont été développées sous l’impulsion du monde de la recherche comme de l’industrie, étant donnés les liens des VANETs avec la sécurité routière, l’internet des objets (IoT/WoT : Internet of Things/Web of Things) pour les systèmes de transport intelligents (ITS : Intelligent Transportation Systems), les villes intelligentes et les villes vertes. Composant essentiel des VANETs, les protocoles de communication inter-véhicules (IVC : Inter-Vehicle Communication) font face à des défis techniques, en particulier à cause de la diversité des applications dans lesquelles ils sont impliqués. Dans cette thèse, après une présentation des VANETs et de l’état de l’art des IVC, nous proposons un protocole de dissémination de données, TrAD, conçu pour diffuser de manière efficiente des messages d’une source vers les véhicules présents dans la zone d’intérêt (ROI : Range of Interest). TrAD se base sur les états du trafic routier et du trafic réseau pour adapter localement la stratégie et les paramètres de transmission des données afin d’optimiser les performances des applications qui l’utilisent. De plus, un algorithme de classification des clusters locaux de véhicules est conçu pour permettre l’usage de TrAD sur autoroute aussi bien qu’en ville. Pour éviter l’encombrement des canaux de communication, un mécanisme illustratif de contrôle de la congestion reposant sur une approche distribuée est utilisé. Trois protocoles IVC de l’état de l’art ont été comparés à TrAD dans des scénarios réalistes de simulation, basés sur différentes villes réelles, différents trajets et densités véhiculaires. Les performances de TrAD surpassent celles des protocoles de référence en termes de taux de délivrance des paquets (PDR : Packet Delivery Ratio), nombre de transmissions et latence. De plus, nous montrons que TrAD est tolérant, dans une certaine mesure, aux erreurs sur les données GPS. Pour s’assurer de la qualité des simulations, nous avons étudié le modèle de déplacement employé dans le simulateur de trafic, puis couplé ce dernier au simulateur de réseau, afin que les deux s’échangent des informations en temps-réel. Grâce à la compréhension acquise lors de l’analyse du modèle de déplacement, nous avons pu développer un simulateur de conduite de tramway pour la T2C (Transports en Commun de l’agglomération Clermontoise). Des tests menés sur le matériel roulant nous ont permis d’élaborer des modèles de déplacement fidèles correspondants aux diverses situations rencontrées par le tramway. L’affichage de la simulation est assuré par un flux vidéo ajusté plutôt que des images de synthèse, ce qui permet de limiter le coût de développement tout en garantissant un certain réalisme dans l’affichage. Ce projet est soutenu par la T2C pour une durée de deux ansIn the last two decades, Vehicular Ad hoc Network (VANETs) were developed significantly by both academic institute and industries association, since VANETs originate from traffic safety and are also an important application of Internet of Things / Web of Things (IoT/WoT) for Intelligent Transportation System (ITS), Intelligent Vehicles and Smart Cities. As an essential component of VANETs, Inter-Vehicle Communication (IVC) protocols face many critical challenges, in particular, because they relate to various specific applications. In this thesis, after elaborating on related knowledge of VANETs and state-of-the-art of IVC protocols, we propose a data dissemination protocol for vehicular networking, named TrAD, to disseminate efficiently warning messages from a source to vehicles in a range of interest (ROI). TrAD considers the status of road traffic and network traffic to adapt locally the strategy and the parameters of transmissions in order to optimize the global performance of IVC application. Moreover, a local vehicular cluster classification algorithm is designed to support TrAD to be performed in both highway and urban scenarios. In addition, an illustrative congestion control mechanism is used to avoid channel congestion using a distributed approach. Three state-of-the-art IVC protocols have been compared with TrAD by means of realistic simulations. The performance of all those protocols is evaluated quantitatively in various scenarios by taking into account different real road maps, trafic routes and vehicular densities. Compared with the reference protocols, TrAD gains an outstanding overall performance in terms of packet delivery ratio, number of transmissions and delay. Furthermore, TrAD also can tolerate a reasonable degree of GPS drift while achieving efficient data dissemination. In order to ensure the quality of simulations, we deeply investigated the mobility model of road traffic simulator, and then performed the bidirectionally coupled simulation in which the network simulator and the road trafic simulator can exchange information in real-time. Upon understanding of the mobility model, we obtained a chance to develop a low-cost tram simulator for the local public transportation provider, the T2C (Transports en Commun de l’agglomération Clermontoise). We attempt to design accurate mobility models from different scenarios for the specific type of tram used by T2C. Real world trials are carried out to explore the key parameters required by theoretical deduction for our mobility model. Moreover, the display GUI relies on a video stream, rather than 3D graphics, which can reduce the cost while guaranteeing the quality of service. This project was supported for two years by T2C
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Urzedo, Junior Sérgio. "Identificação de famílias em situação de vulnerabilidade social no Brasil para planejamento de políticas públicas : estudo dos segmentos urbanos das capitais e regiões metropolitanas." Niterói, 2016. https://app.uff.br/riuff/handle/1/2174.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Fundação Centro Estadual de Estatísticas, Pesquisas e Formação de Servidores Públicos do Rio de Janeiro. Coordenadoria de Gestão da Informação. Rio de Janeiro, RJ
Este trabalho teve como objetivo desenvolver uma metodologia de diagnóstico social de modo a ajudar na identificação e ordenação de regiões em termos do grau de vulnerabilidade social. Para tal foi discutido o conceito de vulnerabilidade social (KAZTMAN e FILGUEIRA, 2006) e a relação de sua formulação teórica com as mudanças ideológicas no pensamento econômico. Para tal foi realizada uma análise histórica sobre o pensamento desenvolvimentista, teorias Cepalinas, em especial, nas teorias de Celso Furtado, e sobre a evolução da pobreza e miséria no Brasil. Para construção do Indicador de Vulnerabilidade Social (IVS) utilizou-se o conceito de multidimensionalidade para cálculo da vulnerabilidade das famílias/domicílios. A fonte dos dados foi o censo demográfico de 2010, de onde foram retirados os microdados do universo e através de análise fatorial foi possível ordenar os setores censitários de acordo com sua classificação. Estas informações georreferenciadas possibilitaram a construção de mapas que apontam geograficamente a Vulnerabilidade das famílias/domicílios possibilitando uma análise do microssocial para fins de planejamento público e privado em programas e projetos voltados à assistência social.
This study aimed to develop a methodology for social diagnosis in order to assist in the identification and ordering of regions in terms of the degree of social vulnerability. For this was discussed the concept of social vulnerability (Kaztman and FILGUEIRA, 2006) and the relationship of its theoretical formulation with ideological shifts in economic thinking. For such a historical analysis of development thinking, Cepal theories, especially theories of Celso Furtado, and on the evolution of poverty and misery in Brazil was performed. Construction of Social Vulnerability Indicator (IVS) we used the concept of multidimensionality for calculating the vulnerability of families / households. The data source was the census of 2010, which were removed from the microdata of the universe and through factor analysis it was possible to sort the census tracts according to their classification. This information allowed the construction of georeferenced maps that link geographically Vulnerability of families / households enabling an analysis of the micro for purposes of public and private planning programs and projects aimed at social assistance.
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張介能. "= IVSC-based electrical application, state estimation, and parameter identification." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/62380027148308889030.
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Dubois, Maurice Junior. "Cinétique de la réponse cytokinaire lors d'infections aux Escherichia coli entéropathogènes dans un modèle de culture d'iléon (IVOC) d'origine porcine." Thèse, 2008. http://hdl.handle.net/1866/7195.
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Jiang, Yanan master of cellular and molecular biology. "Manual alignment of IVS sequences and its implication in multiple sequence alignment." Thesis, 2011. http://hdl.handle.net/2152/ETD-UT-2011-12-4706.
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It is recognized that an iterative comparative analysis of large-scale homologous RNAs significantly promote the understanding of an RNA family. The Gutell lab is renowned for maintaining high quality RNA sequence alignments and accurately predicted RNA secondary structures using this approach. While the current available alignment and structure data are mainly obtained by trained domain experts with extensive manual effort, it is highly desired that this process is automated and replicable given the exponentially growing number of RNA sequence data and the amount of time required for expert training. In this thesis, we learn the processes involved in comparative analysis by manually aligning a non-coding RNA family, IVS sequences, with the supervision of Dr. Gutell. Each process is then simulated by mathematical objective functions and algorithms. We also evaluate the current available RNA analysis packages that aim each of the processes. Finally, a new RNA sequence alignment algorithm incorporating structure information that can be extended for different alignment tasks is proposed.text
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Mohr, Alexander T., and J. F. Puck. "Managing functional diversity to improve the performance of international joint ventures." 2005. http://hdl.handle.net/10454/3644.
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NoInternational Joint Ventures (IJVs) have become one of the most important ways for companies to expand their activities and exploit business opportunities abroad. In China, for example, which has become the world's largest recipient of Foreign Direct Investment, IJVs with local companies are the most important way of doing business. However, many companies have learnt that the performance of their joint ventures in China does not meet their expectations. This study focuses on functional diversity - differences in business practices between foreign and local companies - and its influence on IJV performance. We investigate the influence of this functional diversity on the performance of IJVs and discuss how companies can moderate this influence through adaptation, trust, commitment and communication. Hypotheses are formulated and empirically tested using data gathered through a questionnaire survey of managers of German-Chinese IJVs. The results show that although functional diversity has a negative impact on IJV performance, managers can influence the magnitude of this impact. We use insights from interviews with managers of German-Chinese IJVs in China to supplement our discussion and provide some indication of best practice.
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Baspinar, Ebru-Eylem. "Le rôle du motif hydrophobe VAVIM situé au niveau de IVS6 dans les mécanismes d'activation et d'inactivation du canal calcique Caᵥ2.3." Thèse, 2006. http://hdl.handle.net/1866/15774.
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Schorsch, Isabel [Verfasser]. "Die posteriore intravaginale Schlingeneinlage (IVS) zur Behandlung des Level-1-Defekts der Frau / vorgelegt von Isabel Schorsch." 2007. http://d-nb.info/983787719/34.
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Ui-Jing, Kao, and 高玉菁. "Modifiked Conductometric Studies of Acidic Properties of Derivat ivs Benzoic Acid in Mixed Amphiprotic and Aprotic Solvents." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/90122001470834086315.
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碩士淡江大學
化學學系
82
The major works of this research is to study the effects of dielectric constant, autoprotolysis constant, and other physical or chemical constants of mixed amphiprotic and aprotic solvents on the dissociation of derivatives of benzoic acid. The pKa values was estimated by Modified conductometric meth od. Personal computer which was connected with conductometer was used not only for recording the data in measurements but also for calculating the results of experiment. The mixtures of acetone and water in different ratio was use as mixed solvents, and the derivatives of benzoic acid was used as solutes. The pKa values of solutes in different mixed solvent and the effects of physical constants of solvents and the struc- tures of solutes was widely discussed in this paper.
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Deryal, Mustafa [Verfasser]. "Vergleichende Untersuchung zwischen high und low Respondern bezüglich verschiedener Stimulationsprotokolle und deren Einfluß auf das IVF-, IVSI-Ergebnis / vorgelegt von Mustafa Deryal." 2010. http://d-nb.info/1008153788/34.
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Chong, Kah-Wai, and 張家維. "High Incidence of the Fabry Disease Mutation IVS4 +919 G>A in Taiwan and Its Role in Idiopathic Hypertrophic Cardiomyopathy Patients." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/71581869331776565655.
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碩士國立陽明大學
臨床醫學研究所
98
Fabry disease is an X-linked recessive lysosomal storage disease resulting from deficient α-galactosidase A (α-Gal A) activity. The estimated incidence of Fabry disease is about 1 in 50,000 males. Cardiac variant of Fabry disease is an atypical type of Fabry disease with residual α-Gal A activity. Patients with the cardiac variant mutation present hypertrophic cardiomyopathy (HCM) in their middle age. Previous studies have shown that the incidence of Fabry disease in male subjects with myocardial hypertrophy is around 3% to 4%. In Taiwan, Fabry disease newborn screening was initiated from January, 2008. Within 24 months, 205,491 neonates were screened by assaying the α-Gal A activity. Out of these neonates, 74 male and 6 female neonates had low α-Gal A activity and carried GLA gene mutation. Eleven different mutations were detected, including 5 novel missense mutations (p.G104V, p.M296L, p.R301L, p.G360C, p.K391T), 4 known missense mutations (p.R112H, p.A143T, p.R356W, p.R363C), one known nonsense mutation (p.S345X) and one known intronic mutation (IVS4 +919 G>A). The IVS4 +919 G>A mutation was noted to be the most common mutation among these neonates (~81%). In pedigree studies, 21 maternal grandmothers and 20 maternal grandfathers had the intronic mutation. Echocardiography results showed that 10 grandfathers (50%) and 2 grandmothers had HCM. Additionally, the plasma α-Gal A activity and GLA mutation in 43 males with idiopathic HCM were screened, and we found 5 (~11%) males had deficiency of α-Gal A in combination with the intronic mutation. We identified an unexpected high incidence of Fabry disease in Taiwan (~1/1,450 in males). The high percentage of cardiac variant Fabry disease in patients with idiopathic HCM (~11%) suggested that the diagnosis of Fabry disease should be considered in all patients with idiopathic HCM. The early identification of undiagnosed patients allows timely therapeutic intervention, which would provide a better clinical outcome.
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Fernandes, Pedro Manuel de Azevedo Silva. "Platooning of IVC-enabled Autonomous Vehicles: Information and Positioning Management Algorithms, for High Traffic Capacity and Urban Mobility Improvement." Doctoral thesis, 2013. http://hdl.handle.net/10316/23352.
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Tese de doutoramento em Engenharia Eletrotécnica, na especialidade de Instrumentação e Controlo, apresentada à Faculdade de Ciências e Tecnologia da Universidade de CoimbraUrban traffic congestion is one of the major problems our cities face nowadays. The main challenge is to improve road capacity and avoid traffic congestion, under high vehicle density. This thesis aims to contribute for urban mobility improvement, using platooning of IVC-enabled autonomous vehicles. This way, new intraplatoon information management strategies to deal with safe and stable operation are proposed, as well as inter- and intraplatoon positioning management strategies with cooperative behavior to improve the efficiency of an advanced traffic management system. New algorithms to mitigate communication delays are presented, and Matlab/Simulinkbased simulation results are reported. We argue that using anticipatory information from both the platoon’s leader and the followers significantly impacts on platoon string stability. The obtained simulation results suggest that the effects of communication delays may be almost completely canceled out. The platoon presents a very stable behavior, even when subjected to strong acceleration patterns. When the communication channel is subjected to a strong load, proper algorithms may be selected, lowering network load and maintaining string stability. Upon emergency occurrences, the platoon timely response may be ensured by dynamically increasing the weight of the platoons’ leaders data over the behavior of their followers. The simulation results suggest that the algorithms are robust under several demanding scenarios. To assess if current intervehicle communication technology can cope with the proposed information-updating schemes, a research of its operation was conducted through a network simulator. Inter- and intraplatoon positioning management strategies with cooperative behavior are also addressed, to improve the efficiency of an advanced traffic management system. Novel algorithms to ensure high traffic capacity are presented, and Matlab/Simulink-based simulation results are reported. Using underneath the new proposed algorithms to mitigate communication delays with anticipatory information, we consider a constant spacing between platoons’ leaders as a fundamental condition to attain high traffic capacity. As such, new algorithms to maintain interplatoons’ leaders constant spacing are proposed, as well as novel algorithms allowing vehicles to enter the main track cooperatively. Furthermore, a new set of algorithms to improve safety is also presented. A novel architecture was developed, where each vehicle consists of two distinct modules: a leader and a follower. Based on Matlab/Simulink simulations of several scenarios, the new algorithms were assessed and the simulation results presented, confirming that the proposed algorithms ensure high traffic capacity and vehicle density, and avoid traffic congestion. These features were validated through simulations performed on a novel SUMO-based simulation platform. The simulation results proved that the proposed algorithms lead to a clear benefit of a platooning system when compared to bus and light rail-based transit systems.
O congestionamento de tráfego urbano é um dos problemas mais prementes que as nossas cidades enfrentam atualmente. O maior desafio que se coloca consiste em melhorar a capacidade das vias e evitar os congestionamentos, na presença de alta densidade de veículos. Esta tese procura contribuir para a melhoria da mobilidade urbana, com a utilização de platoons de veículos autónomos com comunicações entre veículos. Assim, são propostas novas estratégias de gestão de informação dentro dos platoons para manter uma operação segura e estável, bem como estratégias de gestão de posicionamento de veículos com comportamento cooperativo entre e dentro de platoons com o intuito de melhorar a eficiência de um sistema avançado de gestão de tráfego. São apresentados novos algoritmos para mitigar os atrasos das comunicações, bem como resultados de simulações efetuadas em Matlab/Simulink. Afirmamos que a utilização de informação antecipada, tanto por parte do líder do platoon como dos seus seguidores, produz uma melhoria muito significativa na estabilidade da cadeia de veículos de um platoon. Os resultados obtidos através de simulações indicam que os efeitos dos atrasos das comunicações podem ser quase completamente anulados. O platoon apresenta um comportamento muito estável, mesmo quando sujeito a fortes acelerações. Quando o canal de comunicação está muito ocupado, podem ainda ser selecionados algoritmos adequados, para atenuar a carga do canal de comunicação e manter a estabilidade da cadeia de veículos. Na hipótese de ocorrerem situações de emergência, a resposta pronta do platoon pode ser assegurada pelo aumento do peso da informação dos líderes dos platoons sobre os respetivos seguidores, efetuada de forma dinâmica. Os resultados de simulação sugerem que os algoritmos são robustos em diversos cenários exigentes. Para proceder à avaliação da capacidade das atuais tecnologias de comunicação entre veículos de lidarem com os esquemas de atualização de informação propostos, foram também efectuadas simulações num simulador de redes. Nesta tese são também apresentadas estratégias de gestão de posicionamento de veículos com comportamento cooperativo, entre e dentro de platoons, para melhorar a eficiência de um sistema avançado de gestão de tráfego. São apresentados novos algoritmos para garantir elevada capacidade de tráfego, e são relatados resultados de simulações efetuadas em Matlab/Simulink. Com a utilização nas camadas inferiores do sistema dos novos algoritmos propostos para mitigar os atrasos das comunicações através de informação antecipada, consideramos como condição fundamental para a obtenção de elevada capacidade de tráfego o espaçamento constante entre os líderes dos platoons. Para tal, são propostos novos algoritmos para manter um espaçamento constante entre os líderes dos platoons, bem como novos algoritmos para permitir aos veículos a sua entrada na via de forma cooperativa. Além disso, também é apresentado um novo conjunto de algoritmos para aumentar a segurança. Foi desenvolvida uma nova arquitetura, onde cada veículo é composto por dois módulos: um líder e um seguidor. Os novos algoritmos foram avaliados através de simulações de vários cenários efetuadas em Matlab/Simulink e os resultados apresentados confirmam que os algoritmos propostos garantem elevada capacidade de tráfego e alta densidade de veículos, e evitam congestionamentos. Estas caraterísticas foram validadas através de simulações efetuadas numa nova plataforma de simulação baseada no simulador de tráfego SUMO. Os resultados das simulações demonstraram que os algoritmos propostos conferem ao sistema de platoons uma evidente vantagem, quando comparado com sistemas de transporte baseados em autocarros e metros de superfície.
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McNeilly, Meghan Scott. "Polycyclic aromatic hydrocarbons from the Chattanooga Creek flood plain and their effects on endothelial cells via group IVC phospholipase A₂." 2005. http://etd.utk.edu/2005/McNeillyMeghan.pdf.
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Thesis (M.S.) -- University of Tennessee, Knoxville, 2005.Title from title page screen (viewed on July 7, 2005). Thesis advisor: Patricia K. Tithof. Document formatted into pages (ix, 48 p. : ill. (some col.), map). Vita. Includes bibliographical references (p. 38-47).
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Huang, Wei-Lin, and 黃薇霖. "Generation of induced pluripotent stem cells from peripheral blood mononuclear cells by using a non-viral method to decipher the gene expression of Fabry disease IVS4+919 G>A mutation." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/98177749571047682274.
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碩士國立陽明大學
解剖學及細胞生物學研究所
102
Fabry disease (FD) is an X-linked lysosomal storage disorder, due to mutations in the α-galactosiase A gene (GLA) leads to deficient or absent lysosomal enzyme, α-galactosidase A activity, progressive accumulation of globotriaosylceramide (Gb3) in lysosome of a variety of cell types. As the disease progresses, left ventricular hypertrophy, renal failure and strokes may occur. According to the newborn screening study in Taiwan, an unexpected high prevalence of the cardiac variant mutation IVS4+919G>A. Enzyme replacement therapy (ERT) is currently the only effective therapy to reduce Gb3 accumulations in Fabry disease. Although it improves cardiac function and left ventricular mass, Gb3 clearance upon ERT has been demonstrated in cardiac capillary endothelium but not in cardiomyocytes of patients. It is also limited to trace and analyze the efficacy of ERT from patient’s biopsy, especially from heart. In current study, we would like to investigate how the cardiac function is improved via ERT in differentiated cardiomyocytes of Fabry patients. In brief, the induced pluripotent stem cells (iPSC) generated from Fabry patients’ PBMCs and differentiated into patient-specific cardiomyocytes. Immunofluorescence results showed Gb3 accumulates in the cardiomyocytes and results in phenotype changes (cell enlargement), which is correspond to those found in cardiac tissue from Fabry patients. Using the patient-specific differentiated cardiomyocyte model, we demonstrated that ERT was able to prevent accumulation of lysosomal Gb3 in cardiomyocyte. The gene expression profile of Fabry-derived cardiomyocyte may provide some candidates for further investigation on pathogenic mechanisms of cardiac manifestations in Fabry disease.
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Barroso, Ana Catarina Marques. "Estudo preliminar sobre a frequência das redes sociais e a caracterização de dimensões da personalidade de vítimas de violência em relações intimas." Master's thesis, 2019. http://hdl.handle.net/10437/9896.
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Orientação: Laura AlhoO presente estudo teve como objetivo verificar se o contacto com as redes sociais favorece o fenómeno de violência em relações íntimas e sugere características de personalidade distintas entre vítimas e não vítimas. Uma amostra de 172 indivíduos do sexo masculino e feminino, com idade superior a 18 anos participaram neste estudo. Foi aplicado um questionário sociodemográfico, que incluiu questões acerca das relações amorosas e hábitos online dos participantes, o Inventário NEO FFI-20 (Bertoquini & Pais Ribeiro, 2006 na adaptação portuguesa com 20 itens de Costa & McCrae, 1992) e o Inventário de Violência Conjugal (IVC. de Machado, Gonçalves e Matos, 2015). Após os dados recolhidos, a amostra foi dividida em vítimas de atos abusivos e “não-vítimas” (indivíduos que nunca sofreram qualquer comportamentos abusivo por parte dos seus parceiros amorosos). Os resultados apresentaram um maior número de vítimas do sexo feminino, e dois domínios de personalidade (Amabilidade e a Extroversão) demonstraram ser significativos quanto à utilização das redes sociais, o primeiro domínio sugerindo que sujeitos mais amáveis apresentaram um uso médio de uma a cinco horas e indivíduos com valor mais alto de extroversão, uma frequência média de 10 a 15 horas diárias.
The present study aimed to verify if contact with social networks supported the phenomenon of violence in intimate relationships and suggested distinct personality traits between victims and non-victims. A sample of 172 males and females aged over 18 years participated in this study. The NEO FFI-20 Inventory (Bertoquini & Pais Ribeiro, 2006 in the Portuguese adaptation with 20 items by Costa & McCrae, 1992) and the Inventory of Conjugal Violence (IVC de Machado, Gonçalves and Matos, 2015) were applied and also a sociodemographic questionnaire, which included questions about the participants’ relationships and online habits. After the data collected, the sample was divided into victims of abusive and "non-victim" (individuals who never suffered any abusive behavior from their loving partners). The results showed a greater number of female victims, and two personality domains (Amiability and Extroversion), were shown to be significant regarding the use of social networks, the first domain suggesting that subjects with higher values in Agreeableness presented an average use of one to five hours and individuals with a higher value of extraversion, an average frequency of 10 to 15 hours per day.
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Čapková, Šárka. "Mezinárodní dobrovolnictví a jeho role v profesním a osobnostně sociálním rozvoji." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-323005.
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This diploma thesis investigates international volunteering in the context of professional, personal and social development of young volunteers. In the theoretical part, definition, history, forms and subjects involved are presented, together with the impacts and ethical questions related to the field. Next, the professional, personal and social development is defined and international volunteering is put in light as a source of important skills. The empirical part is concerned with one specific form of international volunteering - workcamps. Firstly, organisation INEX-SDA, which sends hundreds of youngsters to workcamps each year, is introduced. Next, methodology and results of an original qualitative research focused on the role of workcamps in workcamp-participants' lifes are discussed. The results suggest that workcamps have various impacts on and connectedness with the participants' development, the professional as well as the personal and social. By some, the workcamp's impact on their life and development is perceived as subtle, while others see significant effects, workcamps had on their life and skills. Whole spectrum of skills and values that can be acquired on workcamps is revealed and described in relation to career and personal life. Key words international volunteering, international...
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Barreto, Leopoldo Melo. "Educação Ambiental para a Sustentabilidade: um estudo sobre a formação de futuros Licenciados em Biologia centrada no uso de aquários em projetos orientados para a ação ambiental sustentável no ensino médio." Doctoral thesis, 2017. http://hdl.handle.net/1822/48705.
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A Educação Ambiental para a Sustentabilidade (EA) tem sido um assunto prioritário ao
redor do mundo. Na EA no contexto escolar, o/a docente ocupa um papel crucial, sendo
essencial melhorar a sua formação nessa área. Assim, esta investigação foi desenhada para
responder ao seguinte problema: “Quais são os efeitos da formação de futuros/as docentes de
Biologia, centrada no uso do aquário em EA orientada para a ação, no desenvolvimento dos seus
conhecimentos e competências profissionais para desenvolver a competência para a ação
ambiental em alunos/as do ensino médio?”
Foram organizados dois estudos complementares, com um desenho de investigação
misto. Recolheram-se os dados através de uma entrevista inicial e final a formandos/as, um
questionário inicial e final a alunos/as do ensino médio, diários de bordo de formandos/as e
investigador e material produzido pelos/as formandos/as e alunos/as do ensino médio. No
primeiro estudo foi realizada uma oficina de formação (48h) com futuros/as docentes de
Biologia (n=12). O segundo estudo, focado nos alunos/as (n=33), consistiu na sua participação
extra-aula num projeto de EA orientado para a ação. Como principais resultados destacamos que
a oficina teve um impacto positivo no aumento dos conhecimentos e competências profissionais
dos/as futuros/as docentes para fazerem EA orientada para a ação, nomeadamente no
conhecimento do conteúdo (100%), pedagógico geral (58%), pedagógico do conteúdo (42%) e
contexto educativo (25%). Mais de metade sentiu-se mais capacitada para utilizar a metodologia
IVAM na EA (58%). O projeto de EA aumentou a competência dos alunos/as para realizarem
ações ambientais. O aquário ocupou um papel importante na melhoria dos seus conhecimentos
sobre o ecossistema aquático e na compreensão sobre a importância da água. Logo concluiu-se
que a metodologia IVAM com utilização do aquarismo, foi eficaz na promoção da competência
para a ação, tanto a nível universitário, como na educação básica. Esta é a principal implicação
deste estudo, pois pode ser uma alternativa metodológica útil na EA para a sustentabilidade nos
dois níveis de ensino, conduzindo o cidadão e professores/as a agirem e/ou educarem no
sentido de mitigar os problemas identificados.Environmental Education for Sustainability (EE) has been a priority issue in governmental and non-governmental institutions around the world. In EE in the school context, teachers play a crucial role, and it is considered essential the enhancement of their formation in this area. In this sense, this research was designed to answer the following problem: "What are the effects of the formation of future biology teachers, centred in the use of the aquarium in action-oriented EE, in the development of their professional knowledge and competences to develop high school students’ environmental action competence?" Therefore, two complementary studies were organized with a mixed research design. Data were collected through an initial and final interview to trainees, an initial and final questionnaire to high school students, logbooks of trainees and researcher and material produced by the trainees and the high school students. In the first study, a training workshop (48h) with future biology teachers was conducted (n = 12). The second study was focused on students (n = 33), and consisted in their extra-class participation in an action-oriented EE project. From the main results, we can point out that the workshop had a positive impact on increasing the knowledge and skills of future teachers to carry out action-oriented EE, namely in content knowledge (100%), general pedagogic knowledge (58%), pedagogic content knowledge (42%), and educational context (25%). More than half felt better able to use the IVAC methodology in EE (58%). This action-oriented EE project increased the competence of high school students to carry out environmental actions. The aquarium occupied an important role in improving knowledge about the aquatic ecosystem and increased understanding of the importance that water has for life. Therefore, it is possible to conclude that the IVAC methodology with the use of the aquarium was effective in promoting environmental action competence, both at university and higher education levels. This is the main implication of this study as it can be a useful methodological alternative in the EE for sustainability in both educational levels, leading citizens and teachers to take action and/or educate others in order to mitigate the identified problems.