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Journal articles on the topic 'J82'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Young, Lawrence D. "Influence of Soybean Cropping Sequences on Seed Yield and Female Index of the Soybean Cyst Nematode." Plant Disease 82, no. 6 (1998): 615–19. http://dx.doi.org/10.1094/pdis.1998.82.6.615.

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Several soybean (Glycine max) cropping sequences were planted for 12 years in a field that, at the beginning of the test, was infested with race 14 of the soybean cyst nematode, Heterodera glycines. Continuous soybean cropping sequences included H. glycines-susceptible cultivars Forrest, J82-21, Peking × Centennial breeding line, and moderately resistant cultivars Bedford and J81-116. Forrest treated with aldicarb or pentachloronitrobenzene (PCNB) plus metalaxyl and resistant breeding line JS83-236 followed by resistant cultivars Cordell and Hartwig were additional continuous soybean sequences

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2

Chien, Tsu-Ming, Kuang-Han Wu, Ya-Ting Chuang, et al. "Withaferin a Triggers Apoptosis and DNA Damage in Bladder Cancer J82 Cells through Oxidative Stress." Antioxidants 10, no. 7 (2021): 1063. http://dx.doi.org/10.3390/antiox10071063.

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Withaferin A (WFA), the Indian ginseng bioactive compound, exhibits an antiproliferation effect on several kinds of cancer, but it was rarely reported in bladder cancer cells. This study aims to assess the anticancer effect and mechanism of WFA in bladder cancer cells. WFA shows antiproliferation to bladder cancer J82 cells based on the finding of the MTS assay. WFA disturbs cell cycle progression associated with subG1 accumulation in J82 cells. Furthermore, WFA triggers apoptosis as determined by flow cytometry assays using annexin V/7-aminoactinomycin D and pancaspase detection. Western blot

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3

Edmonds, Eric V., and Norbert Schady. "Poverty Alleviation and Child Labor." American Economic Journal: Economic Policy 4, no. 4 (2012): 100–124. http://dx.doi.org/10.1257/pol.4.4.100.

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Poor women with children in Ecuador were selected at random for a cash transfer that is less than 20 percent of median child labor earnings. Poor families with children in school at the time of the award use the transfer to postpone the child's entry into the labor force. Students in families induced to take up the transfer by the experiment reduce paid employment by 78 percent and unpaid economic activity inside their home by 32 percent. Time in unpaid household services increases, but overall time spent working declines. (JEL I32, I38, J13, J22, J82, O12)

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Mookherjee, Dilip, Silvia Prina, and Debraj Ray. "A Theory of Occupational Choice with Endogenous Fertility." American Economic Journal: Microeconomics 4, no. 4 (2012): 1–34. http://dx.doi.org/10.1257/mic.4.4.1.

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Theories based on partial equilibrium reasoning alone cannot explain the widespread negative cross-sectional correlation between parental wages and fertility, without restrictive assumptions on preferences and childcare costs. We argue that incorporating a dynamic general equilibrium analysis of returns to human capital can help explain observed empirical patterns. Other by-products of this theory include explanations for intergenerational mobility without stochastic shocks, connections between mobility and fertility patterns, and locally determinate steady states. Comparative statics exercise

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Kim, Hyera, Su Jin Lee, In Kyoung Lee, et al. "Synergistic Effects of Combination Therapy with AKT and mTOR Inhibitors on Bladder Cancer Cells." International Journal of Molecular Sciences 21, no. 8 (2020): 2825. http://dx.doi.org/10.3390/ijms21082825.

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Despite comprehensive genomic analyses, no targeted therapies are approved for bladder cancer. Here, we investigate whether a single and combination therapy with targeted agents exert antitumor effects on bladder cancer cells through genomic alterations using a three-dimensional (3D) high-throughput screening (HTS) platform. Seven human bladder cancer cell lines were used to screen 24 targeted agents. The effects of 24 targeted agents were dramatically different according to the genomic alterations of bladder cancer cells. BEZ235 (dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of r

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Drake, T. A., W. Ruf, J. H. Morrissey, and T. S. Edgington. "Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line." Journal of Cell Biology 109, no. 1 (1989): 389–95. http://dx.doi.org/10.1083/jcb.109.1.389.

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Tissue factor (TF) is an integral membrane glycoprotein which, as the receptor and essential cofactor for coagulation factors VII and VIIa (FVII and FVIIa, respectively), is the primary cellular activator of the coagulation protease cascade. Previous studies on the procoagulant activity of a variety of cell types (either lysed or in the intact state) have variously been interpreted as showing that TF is either stored intracellularly or is present in a cryptic form in the surface membrane. Using mAbs to TF, we have directly investigated the subcellular localization and functional activity of TF

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7

Gauffin, Karl. "Precariousness on the Swedish labour market: A theoretical and empirical account." Economic and Labour Relations Review 31, no. 2 (2020): 279–98. http://dx.doi.org/10.1177/1035304620919206.

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The purpose of this article is to investigate emerging areas of precarious employment in Sweden. Based on the literature on dimensions of precariousness and neoliberalism, this article will begin with an analysis of the transitioning Swedish welfare state and the contextual environment of precarious employment in Sweden. This will serve as a point of departure for the development of an occupational classification scheme including measures of income and employment security. In an empirical analysis, the occupational classification will be applied to a population-based register material includin

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8

Shang, Anquan, Man Yang, Fujun Shen, et al. "MiR-1-3p Suppresses the Proliferation, Invasion and Migration of Bladder Cancer Cells by Up-Regulating SFRP1 Expression." Cellular Physiology and Biochemistry 41, no. 3 (2017): 1179–88. http://dx.doi.org/10.1159/000464379.

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Background: Bladder cancer is of compelling morbidity and mortality due to its high recurrence rate. Little development has been made in the last decades in the therapy methods. Thus, the mechanism of its growth and invasiveness involving novel molecular targets are needed. Objective: Our research objective is to confirm the hypothesis that miR-1-3p suppresses the proliferation, invasion and migration of bladder cancer cells. Methods: The expression levels of miR-1-3p and SFRP1 were evaluated using RT-qPCR in bladder cancer tissues and cells as well as in normal tissues and cells. J82 cell lin

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9

Wildgoose, P., and W. Kisiel. "Activation of human factor VII by factors IXa and Xa on human bladder carcinoma cells." Blood 73, no. 7 (1989): 1888–95. http://dx.doi.org/10.1182/blood.v73.7.1888.1888.

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Abstract Single chain factor VII is converted by limited proteolysis to its activated form, factor VIIa, by a number of blood coagulation proteases including factor IXa and factor Xa. We have determined the relative rate of human factor VII activation by human factors IXa and Xa in two different systems: one containing Ca++ and human bladder carcinoma (J82) cells, and the other containing Ca++ and mixed brain phospholipids. The rate of factor VII activation was determined by a one stage coagulation assay, and proteolytic cleavage of factor VII was assessed by sodium dodecyl sulfate polyacrylam

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10

Wildgoose, P., and W. Kisiel. "Activation of human factor VII by factors IXa and Xa on human bladder carcinoma cells." Blood 73, no. 7 (1989): 1888–95. http://dx.doi.org/10.1182/blood.v73.7.1888.bloodjournal7371888.

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Single chain factor VII is converted by limited proteolysis to its activated form, factor VIIa, by a number of blood coagulation proteases including factor IXa and factor Xa. We have determined the relative rate of human factor VII activation by human factors IXa and Xa in two different systems: one containing Ca++ and human bladder carcinoma (J82) cells, and the other containing Ca++ and mixed brain phospholipids. The rate of factor VII activation was determined by a one stage coagulation assay, and proteolytic cleavage of factor VII was assessed by sodium dodecyl sulfate polyacrylamide gel e

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11

Hau, Andrew M., Andrew Gilder, Jing-jing Hu, Steven L. Gonias, and Donna E. Hansel. "uPAR and mTORC2 as coupled targets for therapeutics development in bladder cancer." Journal of Clinical Oncology 34, no. 2_suppl (2016): 447. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.447.

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447 Background: Bladder cancer currently ranks as the fifth most common and the single most expensive cancer to manage in the United States. Although it is established that invasive behavior is a major predictor of diminished outcomes for patients with bladder cancer, the molecular mechanisms governing bladder cancer cell invasion are not well understood. The urokinase receptor (uPAR) and mammalian target of rapamycin complex 2 (mTORC2) represent two powerful pro-invasion candidates that have increased expression in high-grade, invasive bladder cancer, though the former has not been characteri

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12

Wang, Chenyin, Alexandra Hamacher, Patrick Petzsch, et al. "Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1." Cancers 12, no. 2 (2020): 337. http://dx.doi.org/10.3390/cancers12020337.

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Occurrence of cisplatin-resistance in bladder cancer is frequent and results in disease progression. Thus, novel therapeutic approaches are a high medical need for patients suffering from chemotherapy failure. The purpose of this study was to test the combination of the DNA methyltransferase inhibitor decitabine (DAC) with the histone deacetylase inhibitor entinostat (ENT) in bladder cancer cells with different platinum sensitivities: J82, cisplatin-resistant J82CisR, and RT-112. Intermittent treatment of J82 cells with cisplatin resulted in the six-fold more cisplatin-resistant cell line J82C

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13

Guo, Yanxia, Zhiyong Liu, Kailin Li, et al. "Paris Polyphylla-Derived Saponins Inhibit Growth of Bladder Cancer Cells by Inducing Mutant P53 Degradation While Up-Regulating CDKN1A Expression." Current Urology 11, no. 3 (2017): 131–38. http://dx.doi.org/10.1159/000447207.

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Objectives: Paris polyphylla var. yunnanensis (PPVY), a Chinese herb, has long been used for cancer treatment, and its steroidal saponins are suggested to exert an anti-tumor activity, however, the underlying mechanism is incompletely understood and their effect on bladder cancer (BC) remains unknown. The present study is thus designed to address these issues. Material and Methods: Total steroidal saponins were extracted with ethanol from PPVY and used to treat BC cells (HT1197 and J82 carrying mutant p53). Gene expression was determined using qPCR and immunoblotting and cell cycle analyzed us

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14

Edmonds, Eric V., Nina Pavcnik, and Petia Topalova. "Trade Adjustment and Human Capital Investments: Evidence from Indian Tariff Reform." American Economic Journal: Applied Economics 2, no. 4 (2010): 42–75. http://dx.doi.org/10.1257/app.2.4.42.

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Does trade policy influence schooling and child labor in low-income countries? We examine this question in the context of India's 1991 tariff reforms. While schooling increased and child labor declined in rural India in the 1990s, these trends are attenuated in districts with employment concentrated in industries losing tariff protection. As the loss of protection causes a relative rise in poverty in affected districts, families reduce schooling to save schooling costs. Girls disproportionately bear the burden of helping their families cope with poverty. (JEL F13, F16, I21, J13, J82, O15, O19)

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15

von Lilienfeld-Toal, Ulf, and Dilip Mookherjee. "The Political Economy of Debt Bondage." American Economic Journal: Microeconomics 2, no. 3 (2010): 44–84. http://dx.doi.org/10.1257/mic.2.3.44.

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What are the effects of restricting bonded labor clauses in tenancy or debt contracts? While such restrictions reduce agents' ability to credibly commit ex ante to repay principals in states where they default on their financial obligations, they also generate a pecuniary externality on other principal-agent pairs by reducing the equilibrium profit earned by principals. This turns out to imply that on both political and normative grounds, restrictions on bonded labor become more attractive when borrowers become wealthier or the range of collateral instruments widens. (JEL D82, D86, J82, K12)

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16

Skeni Monkwe, Elsie, and Solly Matshonisa Seeletse. "Prominent challenges of fixed-term contracts for administrative and professional employees in higher learning institutions of Gauteng Province, South Africa." Problems and Perspectives in Management 14, no. 3 (2016): 650–56. http://dx.doi.org/10.21511/ppm.14(3-3).2016.08.

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The use of temporary workers by organizations is growing, and has extensively extended to higher learning institutions (HLIs). This paper discusses the challenges of fixed term contract administrative and professional employees (FTC A/Ps) in Gauteng Provinces’ HLIs in South Africa. The research methodology used was exploratory. Surveys were used to collect data. The study sample consisted of 107 FTC A/Ps. Primary data were collected using a questionnaire. Text data were analyzed using the thematic content analysis of qualitative design. The study revealed that the HLIs did not provide training

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17

Saban, Ricardo, Marcia R. Saban, Julie Maier, et al. "Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients." American Journal of Physiology-Renal Physiology 295, no. 6 (2008): F1613—F1623. http://dx.doi.org/10.1152/ajprenal.90344.2008.

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Interstitial cystitis (IC) is a chronic and painful bladder syndrome of unknown cause with no reliable biological marker or effective therapy. Vascular endothelial growth factor (VEGF), which plays a key role in bladder inflammation, is closely associated with the vascular alterations observed in patients with IC. However, our recent findings of VEGF receptors (VEGF-Rs) and VEGF coreceptors on nonendothelial cells in human and mouse urothelium suggest that additional VEGF targets and functions are possible in IC bladders. We report here that VEGF-Rs and coreceptors (neuropilins; NRP) are stron

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18

Segerman, Anna, Niklas Arnberg, Anders Erikson, Kristina Lindman, and Göran Wadell. "There Are Two Different Species B Adenovirus Receptors: sBAR, Common to Species B1 and B2 Adenoviruses, and sB2AR, Exclusively Used by Species B2 Adenoviruses." Journal of Virology 77, no. 2 (2003): 1157–62. http://dx.doi.org/10.1128/jvi.77.2.1157-1162.2003.

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ABSTRACT Unlike most adenovirus (Ad) serotypes, the species B Ads do not use the coxsackie-adenovirus receptor as an attachment receptor. The species B attachment receptor(s) has not yet been identified and is also poorly characterized. Species B Ads can be further divided into species B1 and B2 Ads, and these display different organ tropisms, suggesting a difference in receptor usage. We have studied the receptor interactions of the species B1 serotypes 3p and 7p and the species B2 serotypes 11p and 35 and characterized the properties of the species B receptor(s). Reciprocal blocking experime

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19

Kreutz, Marina, Eva Gottfried, Leoni Kunz-Schughart, et al. "Tumor-Derived Lactic Acid Modulates Dendritic Cell Activation and Differentiation." Blood 104, no. 11 (2004): 4246. http://dx.doi.org/10.1182/blood.v104.11.4246.4246.

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Abstract The tumor milieu can influence DC differentiation in vivo and in vitro. We analyzed DC differentiation in a 3-dimensional tumor model and propose a new mechanism of DC modulation by the tumor environment. Monocytes were cultured in the presence of IL-4 and GM-CSF within multicellular tumor spheroids (MCTS) generated from urothelial carcinoma (J82, UMUC3) and melanoma cell lines (MelIm, Mel108). Monocytes invaded the tumor spheroids and differentiated into tumor-associated dendritic cells (TADC) that displayed an altered phenotype compared to DC generated without tumor contact. The exp

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20

Jia, Li, Srinivasa M. Srinivasula, Feng-Ting Liu, et al. "Apaf-1 protein deficiency confers resistance to cytochromec–dependent apoptosis in human leukemic cells." Blood 98, no. 2 (2001): 414–21. http://dx.doi.org/10.1182/blood.v98.2.414.

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The human leukemia cell lines K562, CEM, CEM/VLB100, human leukemic blasts, and the bladder cancer J82 cell line have different sensitivities to UV light–induced apoptosis. It is reported that resistance to UV light–induced apoptosis occurs at a point in the apoptotic pathway upstream of caspase-3 but downstream of mitochondrial cytochrome c release. It is demonstrated that the block is due to deficiency of Apaf-1, a critical member of the apoptosome. Sensitivity to apoptosis was independent of caspase-9b or XIAP (inhibitors of apoptosis proteins) expression or levels of procaspase-9. Transfec

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Otaka, Toshinori, Tomohiro Yamazaki, and Takayuki Hamamoto. "A Macro-Pixel Based CMOS Image Sensor for Scene Understanding." Journal of The Institute of Image Information and Television Engineers 67, no. 3 (2013): J82—J88. http://dx.doi.org/10.3169/itej.67.j82.

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22

Santoni, Matteo, Consuelo Amantini, Maria Beatrice Morelli, et al. "Different effects of sunitinib, sorafenib, and pazopanib on inducing cancer cell death: The role of autophagy." Journal of Clinical Oncology 31, no. 6_suppl (2013): 270. http://dx.doi.org/10.1200/jco.2013.31.6_suppl.270.

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270 Background: Tyrosine kinase inhibitors (TKI), such as sunitinib, sorafenib and pazopanib, have replaced immunotherapy as the standard of care for metastatic renal cell carcinoma (mRCC). However, their use in sequential or combined strategies is limited by the lack of evidences on the ability of TKIs to induce cell death in cancer cells. Aim of our study was to evaluate the different mechanisms responsible of the cytotoxic effects induced in vitro by µM doses of sunitinib, sorafenib and pazopanib in 5637 and J82 bladder cancer (BC) cell lines. Methods: The viability of BC cell lines were te

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Atiq-ur-Rehman, Mr, Hafsa Anis, and Saud Ahmed Khan. "Skill Shortage versus Subject Choice: Case of Pakistan." Pakistan Development Review 48, no. 4II (2009): 487–96. http://dx.doi.org/10.30541/v48i4iipp.487-496.

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Higher Education is believed to be a very important determinant of economic growth. The growth can be optimised with a suitable combination of skills in various subjects. A mismatch between required combination of skills and available combination of skills carries heavy costs for developing economies since import of skill from foreign is much more in expensive for such economies. We compare skill shortage in Pakistan with the subjects choice of students recently enrolled in institutes of higher learning. We found that there is a mismatch between skill shortage and the enrolment trend. We propo

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Jakse, G., C. Marth, J. Zechner, and G. Daxenbichler. "Antiproliferative effect of hu-interferon-gamma in 674V and J82 bladder carcinoma cell lines." Urological Research 16, no. 6 (1988): 403–5. http://dx.doi.org/10.1007/bf00280019.

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Nucciarelli, Fabio, Ettore Mearini, and Alba Minelli. "Effects of adenosine on prostate adenocarcinoma PC-3 and bladder carcinoma J82 cell lines." Drug Development Research 58, no. 4 (2003): 390–95. http://dx.doi.org/10.1002/ddr.10183.

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Rick, Ferenc G., Petra Popovics, Norman L. Block, et al. "Treatment of urinary bladder cancers by growth hormone-releasing hormone antagonists: A preclinical report." Journal of Clinical Oncology 34, no. 2_suppl (2016): 433. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.433.

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433 Background: Urinary bladder cancer is the fifth most frequent cancer diagnosed and among the most expensive cancers to treat in the United States. The management of muscle-invasive tumors presents a clinical challenge because of the toxicity and limitations in efficacy and durability of current therapeutic modalities. Novel therapeutic strategies for this disease are of paramount importance. Growth hormone-releasing hormone (GHRH) receptors and its splice variant were detected in a series of urothelial malignancies and GHRH has been shown to influence the growth of these tumors. Herein we

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Sakai, T., T. Lund-Hansen, L. Paborsky, A. H. Pedersen, and W. Kisiel. "Binding of human factors VII and VIIa to a human bladder carcinoma cell line (J82)." Journal of Biological Chemistry 264, no. 17 (1989): 9980–88. http://dx.doi.org/10.1016/s0021-9258(18)81756-2.

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Lu, Yi-Chien, Chiung-Nien Chen, Chia-Ying Chu та ін. "Calreticulin activates β1 integrin via fucosylation by fucosyltransferase 1 in J82 human bladder cancer cells". Biochemical Journal 460, № 1 (2014): 69–80. http://dx.doi.org/10.1042/bj20131424.

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We demonstrated that calreticulin regulated bladder cancer cell adhesion through modifying α1,2-linked glycan on β1-integrin, which was catalysed by fucosyltransferase 1. Most importantly, higher levels of fucosylation directly activated β1-integrin. We provide a potential clinical treatment strategy for bladder cancer patients.

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Fredericks, William J., Huiyi Wang, Yomgmu Zheng, et al. "ELEVATED TERE 1 PROTEIN INDUCES CYTOKINE EXPRESSION IN J82 BLADDER CANCER AND HUMAN IMMUNE CELLS." Journal of Urology 179, no. 4S (2008): 263–64. http://dx.doi.org/10.1016/s0022-5347(08)60764-8.

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Lakic, Dragana, Ivana Tadic, Marina Odalovic, Ljiljana Tasic, Ana Sabo, and Aleksandra Mecava. "Analysis of antibiotic consumption for treating respiratory tract infections in children and compliance with the national clinical guidelines." Medical review 67, no. 9-10 (2014): 282–89. http://dx.doi.org/10.2298/mpns1410282l.

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Introduction. Respiratory infections are the most common infections in children. The aims of the study were to analyze the use of antibiotics for respiratory infections in the period 2008 - 2010 in children?s population in region of Nis and to estimate the rational use of antibiotics in relation to the recommendations of the National Guidelines for physicians in primary care. Material and methods. Data source was a Pharmacy Nis database. Antibiotics prescriptions were selected for the following diagnoses: H65-H75 (acute otitis media, mastoiditis), J01 (acute sinusitis), J02-J03 (tonsillopharyn

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Chien, Tsu-Ming, Ti-Chun Chan, Steven Kuan-Hua Huang, et al. "Role of Microtubule-Associated Protein 1b in Urothelial Carcinoma: Overexpression Predicts Poor Prognosis." Cancers 12, no. 3 (2020): 630. http://dx.doi.org/10.3390/cancers12030630.

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We sought to examine the relationship between microtubule-associated proteins (MAPs) and the prognosis of urothelial carcinoma by assessing the microtubule bundle formation genes using a reappraisal transcriptome dataset of urothelial carcinoma (GSE31684). The result revealed that microtubule-associated protein 1b (MAP1B) is the most significant upregulated gene related to cancer progression. Real-time reverse-transcription polymerase chain reaction was used to measure MAP1B transcription levels in urothelial carcinoma of the upper tract (UTUC) and the bladder (UBUC). Immunohistochemistry was

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Anderson, Gordon, and Lucy Kenner. "Enhancing the effectiveness of minimum employment standards in New Zealand." Economic and Labour Relations Review 30, no. 3 (2019): 345–65. http://dx.doi.org/10.1177/1035304619862699.

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Employer breaches of New Zealand’s minimum employer standards and other forms of worker exploitation have been increasingly recognised as a significant problem. This affects migrant workers in particular, and among them those working without documentation or on various types of non-resident visas. Exploitation has become particularly embedded in a number of industries: fishing, hospitality and tourism, and in some sectors of agriculture, particularly those dependent on seasonal labour. Initially, government action to mitigate these problems was slow and reluctant but over the last decade, culm

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Pedersen, Anders H., Torben Lund-Hansen, Yutaka Komiyama, Lars C. Petersen, Per B. Oestergård, and Walter Kisiel. "Inhibition of Recombinant Human Blood Coagulation Factor VIIa Amidolytic and Proteolytic Activity by Zinc Ions." Thrombosis and Haemostasis 65, no. 05 (1991): 528–34. http://dx.doi.org/10.1055/s-0038-1648184.

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SummaryAlthough it is well established that calcium is an essential cofactor in blood coagulation, recent experimental evidence suggests that zinc may also play an important role in hemostasis. In the present study, we have examined the effects of zinc ions on the amidolytic and proteolytic activity of recombinant factor VIIa in the presence of physiological levels of calcium ions. The amidolytic activity of factor VIIa was inhibited half-maximally by 20 ΜM zinc. The amidolytic activity of a derivative of factor VIIa lacking the Γ-carboxyglutamic acid domain was also inhibited half-maximally b

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Koike, Kento, Takahito Tomoto, Tomoya Horiguchi, and Tsukasa Hirashima. "Intelligent Learning Support for Reusability Oriented Knowledge Organization in Programming Learning." Transactions of the Japanese Society for Artificial Intelligence 35, no. 5 (2020): C—J82_1–17. http://dx.doi.org/10.1527/tjsai.35-5_c-j82.

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HUANG, PENG, MASAMI WATANABE, HARUKI KAKU, et al. "Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line." Molecular and Clinical Oncology 1, no. 1 (2012): 180–84. http://dx.doi.org/10.3892/mco.2012.29.

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BLOMQUIST, Andrea, Guntram SCHWÖRER, Helge SCHABLOWSKI, et al. "Identification and characterization of a novel Rho-specific guanine nucleotide exchange factor." Biochemical Journal 352, no. 2 (2000): 319–25. http://dx.doi.org/10.1042/bj3520319.

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Rho GTPases are implicated in a multitude of cellular processes regulated by membrane receptors, such as cytoskeletal rearrangements, gene transcription and cell growth and motility. Activation of these GTPases is under the direct control of guanine nucleotide exchange factors (GEFs), the Dbl family proteins. By searching protein databases we have identified a novel Rho-GEF, termed p114-Rho-GEF, which similarly to other Rho-GEFs contains a Dbl homology domain followed by a pleckstrin homology domain. p114-Rho-GEF interacted specifically with RhoA, in its nucleotide-free and guanosine 5′-[γ-thi

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Dong, Chunhui, Yihui Liu, Guiping Yu, Xu Li, and Ling Chen. "Study of LBHD1 Expression with Invasion and Migration of Bladder Cancer." Open Life Sciences 14, no. 1 (2019): 440–47. http://dx.doi.org/10.1515/biol-2019-0049.

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AbstractLBHD1 (C11ORF48) is one of the ten potential tumor antigens identified by immunoscreening the urinary bladder cancer cDNA library in our previous study. We suspect that its expression is associated with human bladder cancer. However, the exact correlation remains unclear. To address the potential functional relationship between LBHD1 and bladder cancer, we examined the LBHD1 expression at the mRNA and protein level in 5 different bladder cancer cell lines: J82, T24, 253J, 5637, and BLZ-211. LBHD1 high and low expressing cells were used to investigate the migration, invasion, and prolif

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Zhang, Hao, Jishen Zhang, Bo Guo, Hailan Chen, Dehui Xu, and Michael G. Kong. "The Antitumor Effects of Plasma-Activated Saline on Muscle-Invasive Bladder Cancer Cells In Vitro and In Vivo Demonstrate Its Feasibility as a Potential Therapeutic Approach." Cancers 13, no. 5 (2021): 1042. http://dx.doi.org/10.3390/cancers13051042.

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Muscle-invasive bladder cancer (MIBC) is a fast-growing and aggressive malignant tumor in urinary system. Since chemotherapy and immunotherapy are only useable with a few MIBC patients, the clinical treatment of MIBC still faces challenges. Here, we examined the feasibility of plasma-activated saline (PAS) as a fledgling therapeutic strategy for MIBC treatment. Our data showed that plasma irradiation could generate a variety of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in saline. In vivo tests revealed that pericarcinomatous tissue injection with PAS was effective at pr

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Knüchel, Ruth, J. Feichtinger, A. Recktenwald, et al. "Interactions Between Bladder Tumor Cells as Tumor Spheroids from the Cell Line J82 and Human Endothelial Cells in Vitro." Journal of Urology 139, no. 3 (1988): 640–45. http://dx.doi.org/10.1016/s0022-5347(17)42550-x.

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40

Nunes, Heliane Prudente. "Oferta e procura de emprego para os jovens na região metropolitana de Goiânia (2010-2013)." Revista Brasileira de Desenvolvimento Regional 2, no. 2 (2015): 133. http://dx.doi.org/10.7867/2317-5443.2014v2n2p133-152.

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<p>Esse estudo aborda os aspetos conceituais de emprego e desemprego no Brasil e em Goiás, como suporte teórico para a compreensão do fenômeno da oferta e procura de emprego por parte de jovens, na região metropolitana de Goiânia. A importância dessa pesquisa se justifica pelo fato de que o desemprego constitui um dos maiores problemas no mundo atual e, em especial, no Brasil, que vem enfrentando um descompasso entre o crescimento populacional e a oferta e a procura de emprego. O artigo aborda o universo sócio-cultural do jovem desempregado, buscando examinar como as diferentes dimensões

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Coggiola, Osvaldo. "O trabalho na segunda metade do século XX." Revista Brasileira de Desenvolvimento Regional 4, no. 1 (2016): 031. http://dx.doi.org/10.7867/2317-5443.2016v4n1p031-076.

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Neste artigo se examina o trabalho na segunda metade do século XX. Nos anos que se seguem à Segunda Guerra Mundial houve uma expansão econômica na qual a estabilidade capitalista existiu apenas no centro do sistema, já que uma onda de guerras e revoluções continuou a varrer as nações periféricas. Na Europa oriental, incorporada ao “bloco socialista”, rebeliões operárias contra a burocracia dirigente alcançaram Berlim oriental (1953), Hungria (1956), Tchecoslováquia (1968), Polônia (1956, 1971). Ainda tiveram lugar desenvolvimentos revolucionários da classe operária na Ásia e na América Latina

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42

Monteiro-Reis, Sara, Ana Lameirinhas, Vera Miranda-Gonçalves, et al. "Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion." Cancers 12, no. 5 (2020): 1066. http://dx.doi.org/10.3390/cancers12051066.

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Sirtuins are emerging players in cancer biology and other age-related disorders, and their putative role in bladder cancer (BlCa) remains elusive. Further understanding of disease biology may allow for generation of more effective pathway-based biomarkers and targeted therapies. Herein, we aimed to illuminate the role of sirtuins’ family in BlCa and evaluate their potential as disease biomarkers and therapeutic targets. SIRT1-7 transcripts and protein levels were evaluated in a series of primary BlCa and normal bladder mucosa tissues. SIRT7 knockdown was performed through lentiviral transducti

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Kujdowicz, Monika, Wojciech Placha, Brygida Mech, Karolina Chrabaszcz, Krzysztof Okoń, and Kamilla Malek. "In Vitro Spectroscopy-Based Profiling of Urothelial Carcinoma: A Fourier Transform Infrared and Raman Imaging Study." Cancers 13, no. 1 (2021): 123. http://dx.doi.org/10.3390/cancers13010123.

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Markers of bladder cancer cells remain elusive, which is a major cause of the low recognition of this malignant neoplasm and its recurrence. This implies an urgent need for additional diagnostic tools which are based on the identification of the chemism of bladder cancer. In this study, we employed label-free techniques of molecular imaging—Fourier Transform Infrared and Raman spectroscopic imaging—to investigate bladder cancer cell lines of various invasiveness (T24a, T24p, HT-1376, and J82). The urothelial HCV-29 cell line was the healthy control. Specific biomolecules discriminated spatial

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Soddell, Jacques A., Fiona M. Stainsby, Kathryn L. Eales, Reiner M. Kroppenstedt, Robert J. Seviour, and Michael Goodfellow. "Millisia brevis gen. nov., sp. nov., an actinomycete isolated from activated sludge foam." International Journal of Systematic and Evolutionary Microbiology 56, no. 4 (2006): 739–44. http://dx.doi.org/10.1099/ijs.0.63855-0.

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The taxonomic position of two mycolic-acid-producing actinomycetes, isolates J81T and J82, which were recovered from activated sludge foam, was clarified. Comparative 16S rRNA gene sequence studies indicated that the organisms formed a distinct lineage within the Corynebacterineae 16S rRNA gene tree. The taxonomic integrity of this group was underpinned by a wealth of phenotypic data, notably characteristic rudimentary right-angled branching. In addition, isolate J81T contained the following: meso-diaminopimelic acid, arabinose and galactose; N-glycolated muramic acid residues; a dihydrogenate

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45

Piao, Songzhe, Chaoqian Chen, Xin Wang, Licai Mo, Tao Hong, and Mang Ke. "Lycium barbarum Polysaccharides Enhance T-Cell Function by Inhibiting Programmed Death-Ligand 1 via Phosphoinositide-3-Kinase/Protein Kinase B Suppression in Bladder Cancer Cells." Current Topics in Nutraceutical Research 19, no. 3 (2020): 295–302. http://dx.doi.org/10.37290/ctnr2641-452x.19:295-302.

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Lycium barbarum is a boxthorn that produces the goji berries. L. barbarum polysaccharide is a water soluble bioactive component extracted from L. barbarum L. that has been shown to exert multiple pharmacological effects including antitumor effects. Herein, we have explored the mechanism underlying inhibition of tumor growth in J82 bearing bladder carcinoma by L. barbarum polysaccharides. The results of in vitro studies show that L. barbarum polysaccharide inhibited the expression of programmed death-ligand 1 protein, but not the gene transcription in bladder carcinoma cells. Also, L. barbarum

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Lu, Yi-Chien, Chiung-Nien Chen, Bojeng Wang, et al. "Changes in Tumor Growth and Metastatic Capacities of J82 Human Bladder Cancer Cells Suppressed by Down-Regulation of Calreticulin Expression." American Journal of Pathology 179, no. 3 (2011): 1425–33. http://dx.doi.org/10.1016/j.ajpath.2011.05.015.

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Liu, Zhi-Wu, and Richard R. C. Wang. "Genome constitutions of Thinopyrum curvifolium, T. scirpeum, T. distichum, and T. junceum (Triticeae: Gramineae)." Genome 36, no. 4 (1993): 641–51. http://dx.doi.org/10.1139/g93-085.

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The objective of this study is to elucidate genome constitutions of Thinopyrum curvifolium (Lange) D.R. Dewey, T. scirpeum (K. Presl) D.R. Dewey, T. distichum (Thunb.) A. Löve, and T. junceum (L.) A. Löve. Hybrids of T. sartorii (Boiss. &Heidr.) A. Löve with T. scirpeum and T. junceum, as well as the hybrid between T. curvifolium and Pseudoroegneria geniculata ssp. scythica (Nevski) A. Löve, were made and chromosome pairing at metaphase I was studied. The karyotype analyses of mitotic cells stained by aceto-orcein were conducted for both hybrids and the four target species. The Giemsa C-ba

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Huang, Cheng-Shuo, Jar-Yi Ho, Jung-Hwa Chiang, Cheng-Ping Yu, and Dah-Shyong Yu. "Exosome-Derived LINC00960 and LINC02470 Promote the Epithelial-Mesenchymal Transition and Aggressiveness of Bladder Cancer Cells." Cells 9, no. 6 (2020): 1419. http://dx.doi.org/10.3390/cells9061419.

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Exosomes are essential for several tumor progression-related processes, including the epithelial–mesenchymal transition (EMT). Long non-coding RNAs (lncRNAs) comprise a major group of exosomal components and regulate the neoplastic development of several cancer types; however, the progressive role of exosomal lncRNAs in bladder cancer have rarely been addressed. In this study, we identified two potential aggressiveness-promoting exosomal lncRNAs, LINC00960 and LINC02470. Exosomes derived from high-grade bladder cancer cells enhanced the viability, migration, invasion and clonogenicity of recip

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Köhler, Christina U., Michael Walter, Kerstin Lang, et al. "In-Vitro Identification and In-Vivo Confirmation of DNA Methylation Biomarkers for Urothelial Cancer." Biomedicines 8, no. 8 (2020): 233. http://dx.doi.org/10.3390/biomedicines8080233.

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We identified DNA methylation targets specific for urothelial cancer (UC) by genome-wide methylation difference analysis of human urothelial (RT4, J82, 5637), prostate (LNCAP, DU-145, PC3) and renal (RCC-KP, CAKI-2, CAL-54) cancer cell lines with their respective primary epithelial cells. A large overlap of differentially methylated targets between all organs was observed and 40 Cytosine-phosphate-Guanine motifs (CpGs) were only specific for UC cells. Of those sites, two also showed high methylation differences (≥47%) in vivo when we further compared our data to those previously obtained in ou

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Benchagra, Lamiae, Hicham Berrougui, Mohamed Obaidul Islam, et al. "Antioxidant Effect of Moroccan Pomegranate (Punica granatum L. Sefri Variety) Extracts Rich in Punicalagin against the Oxidative Stress Process." Foods 10, no. 9 (2021): 2219. http://dx.doi.org/10.3390/foods10092219.

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Natural antioxidants products are widely distributed in food and medicinal plants. These natural antioxidants, especially polyphenols, exhibit a wide range of biological activities including anti-cancer, anti-inflammatory, and anti-atherosclerosis activities. Pomegranate (Punica granatum L.) is a rich source of polyphenolic components. The purpose of this study was to characterize the phenolic composition and flavonoids and anthocyanin content of different parts (peel and aril) of the Sefri variety of pomegranate. Our results showed that Peel extract was richer in these compounds than that of

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