Journal articles: 'Jacksonville University'

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Bevis, Mary D., and William J. Hubbard. "Jacksonville State University." Serials Librarian 19, no. 1-2 (December 21, 1990): 131–39. http://dx.doi.org/10.1300/j123v19n01_11.

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Rubin, Daniel Ian. "From the Beginning: Creating a Diversity and Multicultural Education Course at Jacksonville State University." Education and Urban Society 50, no. 8 (June 9, 2017): 727–46. http://dx.doi.org/10.1177/0013124517713612.

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In the fall of 2015, a new secondary education class, Diversity and Multicultural Education, was introduced at Jacksonville State University in Jacksonville, Alabama, USA. Although many multicultural theorists emphasize the importance of students taking diversity/multicultural education courses in college, there is no real model for creating such a class. This article creates a framework for how to conceptualize and teach a diversity and multicultural education course at the university level. It discusses the creation of the class through a critical pedagogy framework, the units which comprise the course, and the connection to current events. The article also includes student reflections about personal growth due to taking the new course, as well as personal reflections from the author.

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Garrett, Aaron, and David Thornton. "Librate: The Jacksonville State University Library Book Rating System." International Journal of Technology, Knowledge, and Society 5, no. 2 (2009): 39–54. http://dx.doi.org/10.18848/1832-3669/cgp/v05i02/55986.

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Thornton, Barry, and Gordon Arbogast. "Analyzing Educational Testing Service Graduate Major Field Test Results." American Journal of Business Education (AJBE) 5, no. 5 (August 20, 2012): 531–38. http://dx.doi.org/10.19030/ajbe.v5i5.7209.

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The Educational Testing Service (ETS) created the Graduate Major Field Test in Business (GMFT-B) for MBA students. This test is administered to all MBA classes at Jacksonville University for the purpose of measuring student academic achievement and growth, as well as to assess educational outcomes. The test is given in the capstone course, Business Strategy and Policy, typically taken by students at the end of their MBA program. It provides valuable feedback to each student as to their standing with regard to students across the nation. A total of six years of data (2006 to 2011) was collected for analysis of these test scores. For the first half of this time period, Jacksonville University was in candidacy for accreditation by the Association for the Advancement of Colleges and Schools of Business (AACSB), and for the time period 2009-2011 it was an AACSB accredited institution. Executive MBA, evening MBA (also known as flex MBA) and day-time (accelerated) MBA classes took the exam over that time period. It was determined that the executive MBA student grades were significantly better than their counterparts in the evening (flex) and day-time (accelerated) MBA students at Jacksonville University. It was also found that there was no significant difference in student performance during the first half (AACSB candidacy) and second half (AACSB accreditation) of the time period under investigation.

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Poe, Jodi, and Paula Barnett-Ellis. "Electronic Reserves for the Nursing Programs at Jacksonville State University." Journal of Interlibrary Loan,Document Delivery & Electronic Reserve 17, no. 1-2 (June 26, 2007): 67–81. http://dx.doi.org/10.1300/j474v17n01_09.

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McCULLOUGH, ALAN, FELTON MORRELL, BERNARD THOMAS, VINCENTE WAUGH, NICHOLAS SHUBERT, and AMY DONOFRIO. "The EVAC Movement Story: Why Youth Storytelling Is Powerful . . . and Why It’s Dangerous." Harvard Educational Review 90, no. 2 (June 1, 2020): 195–228. http://dx.doi.org/10.17763/1943-5045-90.2.195.

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In this reflective essay, Alan McCullough Jr., Felton Morrell Jr., Bernard Thomas III, Vincente Waugh, and Nicholas Shubert with their teacher, Amy Donofrio, share the youth self-authorship methods that empowered them to transform their labels from “at-risk youth” to “at-hope youth leaders” in Jacksonville, Florida. After realizing that they had similar experiences with Jacksonville’s extreme violence and crime, they partnered to form the EVAC movement. The power of their shared stories led them from inviting officials to their classroom to hear their stories and collaborate for change to eventually speaking at the White House, meeting President Obama, making the front page of the New York Times, and presenting at Harvard University. In this reflection, the authors share how utilizing the power of youth storytelling in the context of a public school classroom can support youth to heal and lead community change, as well as the ways in which youth stories are dangerous—particularly to the systems of racism and oppression that their stories challenge.

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Johnson, J. W. "Complete Proceedings - Single PDF Download." Coastal Engineering Proceedings 1, no. 6 (January 29, 2011): 0. http://dx.doi.org/10.9753/icce.v6.0.

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This conference was sponsored jointly by the Council on Wave Research and the University of Florida The National Science Foundation assisted by making a grant to pay the travel expenses of some of the foreign authors. Appreciation is expressed to the University of Florida Coastal Engineering Laboratory and to the Jacksonville District of the Corps of Engineers for photographs supplied to illustrate the cover and the section title pages of this publication.

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Murray, Jennifer. "Community engagement: Leveraging library online tools to support local historical organizations." College & Research Libraries News 81, no. 6 (June 11, 2020): 298. http://dx.doi.org/10.5860/crln.81.6.298.

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Among Floridians, Jacksonville is known as the “First Coast.” It is a reference to the fact that Northeast Florida has some of the oldest European settlements in North America. The numerous local historical organizations are forever challenged to preserve and share the rich history of “all that is Jacksonville–including early settlers, 19th- and 20th-century urban planning and architecture, civil rights and Black history, city governance, and our national parks heritage.” They often do not have the resources needed, but local academic libraries are rich in resources and tools that can benefit organizations outside the library and help bring more awareness to the organizations and the collections they have. As the role of academic libraries continues to evolve with technological changes, libraries are continuously looking for ways to reinvent themselves and expand their role within their university and throughout the greater community.

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Lee, Jason W. "Interview With Dan Edwards, Senior Vice President, Communications, Jacksonville Jaguars." International Journal of Sport Communication 6, no. 4 (December 2013): 391–93. http://dx.doi.org/10.1123/ijsc.6.4.391.

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In 2013, Dan Edwards marks his 30th season in the NFL and his 20th year with the Jacksonville Jaguars. He is responsible for overseeing the Jaguars’ communications division, which includes media relations, digital media, and broadcasting. Edwards was promoted to vice president in 2003, when the Jaguars’ community relations and Internet content departments were added to his responsibilities. He is one of eight current Jaguars staff members who have been with the franchise since its first year in 1994. Edwards received a scholarship from NFL Charities in 1984, the year he began his NFL career as a public relations intern in the NFL office in New York. He spent the 1984 football season working in publicity for the Miami Dolphins before joining the Pittsburgh Steelers in 1985. Edwards served as the Steelers’ public relations director from 1987 to 1993. Pittsburgh’s public relations staff received the 1991 Pete Rozelle Award from the Pro Football Writers of America. Edwards, who has worked with the NFL staff at 23 Super Bowls, has an undergraduate degree in business administration with a major in management from the University of Oregon and a master’s degree in sports administration and facility management from Ohio University.

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Fattahi, Tirbod, Rui Fernandes, Luis Vega, Barry Steinberg, and Howard Schare. "Oral and Maxillofacial Surgery at the University of Florida Health Science Center, Jacksonville." Journal of Oral and Maxillofacial Surgery 65, no. 8 (August 2007): 1447–48. http://dx.doi.org/10.1016/j.joms.2007.03.028.

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Riley, Gena, Lawrence A. Beard, and Jennifer Strain. "Assistive technology at use in the teacher education programs at Jacksonville State University." TechTrends 48, no. 6 (November 2004): 47–49. http://dx.doi.org/10.1007/bf02763583.

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Patel, Bijal, Monique Oye, Daniel Norez, and Carmen Isache. "Peripheral blood lymphocyte-to-monocyte ratio as a screening marker for influenza infection." Journal of Investigative Medicine 69, no. 1 (October 1, 2020): 47–51. http://dx.doi.org/10.1136/jim-2020-001335.

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Influenza outbreaks occur annually and account for significant morbidity and mortality. The overall burden of influenza infections, in the USA, for the 2017–2018 season, was an estimated 45 million cases, 810 000 hospitalizations and 61 000 deaths. Literature suggests that leukocyte count and differential, particularly lymphopenia and/or monocytosis, can provide diagnostic value for influenza infection. However, studies regarding these findings are limited in the adult population, particularly in the USA. The objective of this study was to determine if lymphocyte-to-monocyte ratio (L:M)<2 can be used as a screening marker for influenza infection. We performed a retrospective analysis of all patients who presented to University of Florida Health, Jacksonville, a university-affiliated tertiary care center in Jacksonville, Florida, between January 2017 and December 2018, with ‘influenza-like’ symptoms and who were subsequently admitted to the hospital. Patients were divided into two cohorts, based on whether they had laboratory-confirmed influenza versus another confirmed upper respiratory tract viral infection (influenza-like illness (ILI)). L:M was compared between the two groups and was found to be lower in the influenza group compared with the ILI group (p<0.0001). Results of this study demonstrate that a L:M<2 has significant diagnostic value in the acute phase of influenza and can be used for earlier detection and management of this disease, in order to improve clinical outcomes.

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Hayward, Kelsey, Sabrina H. Han, Alexander Simko, Hector E. James, and Philipp R. Aldana. "Socioeconomic patient benefits of a pediatric neurosurgery telemedicine clinic." Journal of Neurosurgery: Pediatrics 25, no. 2 (February 2020): 204–8. http://dx.doi.org/10.3171/2019.8.peds1925.

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OBJECTIVEThe objective of this study was to examine the socioeconomic benefits to the patients and families attending a regional pediatric neurosurgery telemedicine clinic (PNTMC).METHODSA PNTMC was organized by the Division of Pediatric Neurosurgery of the University of Florida College of Medicine–Jacksonville based at Wolfson Children’s Hospital and by the Children’s Medical Services (CMS) to service the Southeast Georgia Health District. Monthly clinics are held with the CMS nursing personnel at the remote location. A retrospective review of the clinic population was performed, socioeconomic data were extracted, and cost savings were calculated.RESULTSClinic visits from August 2011 through January 2017 were reviewed. Fifty-five patients were seen in a total of 268 initial and follow-up PNTMC appointments. The average round-trip distance for a family from home to the University of Florida Pediatric Neurosurgery (Jacksonville) clinic location versus the PNTMC remote location was 190 versus 56 miles, respectively. The families saved an average of 2.5 hours of travel time and 134 miles of travel distance per visit. The average transportation cost savings for all visits per family and for all families was $180 and $9711, respectively. The average lost work cost savings for all visits per family and for all families was $43 and $2337, respectively. The combined transportation and work cost savings for all visits totaled $223 per family and $12,048 for all families. Average savings of $0.68/mile and $48.50/visit in utilizing the PNTMC were calculated.CONCLUSIONSManaging pediatric neurosurgery patients and their families via telemedicine is feasible and saves families substantial travel time, travel cost, and time away from work.

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Tang, Yingqi. "Placing Theory into Practice: An Exploration of Library Services to Distance Learners at Jacksonville State University." Journal of Library & Information Services in Distance Learning 3, no. 3-4 (December 9, 2009): 173–81. http://dx.doi.org/10.1080/15332900903375432.

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Powers, Ann R. "The Preparation of Educational Interpreters for Rural Education Settings." Rural Special Education Quarterly 16, no. 2 (June 1997): 24–32. http://dx.doi.org/10.1177/875687059701600205.

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A need exists to prepare interpreters with specific skills to serve students who are deaf and hard of hearing in various educational settings. Specifically there is a need to prepare educational interpreters to serve students who are deaf or hard of hearing in rural areas. Educational interpreters need a comprehensive educational background as a foundation for serving students with hearing losses in rural educational settings, and as members of the educational team. A consortium was formed consisting of The University of Alabama, the University of Alabama at Birmingham, the University of Montevallo, and Jacksonville State University, for addressing this need. The goal for program participants was the demonstration of skills necessary for interpreting in inclusive rural educational settings and in working in multicultural environments with culturally diverse learners and teachers. The classes offered in this project were to have been conducted on each of the four campuses with several of the courses being offered via the interactive intercampus television system to all students on all four campuses simultaneously.

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Hallaj, Muhammad. "Recollections of the Nakba through a Teenager's Eyes." Journal of Palestine Studies 38, no. 1 (2008): 66–73. http://dx.doi.org/10.1525/jps.2008.38.1.66.

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Muhammad Hallaj, a political scientist specializing in Palestinian affairs and the Israeli-Palestinian conflict, was born in Qalqilya, Palestine, in 1932. After earning his doctorate from the University of Florida in 1966, he taught at Florida's Jacksonville University and then at the University of Jordan in Amman. Hallaj returned to the West Bank in 1975, where he served as dean of social sciences and later as academic vice president of Birzeit University before becoming the first director of the Council for Higher Education in the West Bank and Gaza. While taking a leave to go to Harvard University as a visiting scholar in 1983, Hallaj was denied a visa to return to the West Bank. Among the positions he has held since then have been editor of Palestine Perspectives (1983––1991), member (and subsequent head) of the Palestinian delegation on Refugees to themultilateral peace talks following the Madrid conference (1991––1993), and executive director of the Palestine Center and the Jerusalem Fund. At the request of JPS, Dr. Hallaj shared his memories of the 1948 war and its aftermath, which he experienced as a high school student in Jaffa, and then in Qalqilya and Tulkarm.

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Johnson, Karlie Loren, and Kimberly Westbrooks. "Quelling the Boredom with Alternative Instruction: Augmented Reality, Escape Kits, and Scavenger Hunts." International Journal on Social and Education Sciences 3, no. 1 (January 4, 2021): 180–96. http://dx.doi.org/10.46328/ijonses.65.

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From 2016-2019, Jacksonville State University (JSU) librarians embraced the call to incorporate increased active learning into traditional library information instruction. Librarians began this process by integrating the use of a scavenger hunt into the Houston Cole Library’s new orientation tailgate event. Breakout EDU Escape Room kits with a custom-built storyline were added to teach basic research skills and help lessen library anxiety in First Year Freshman Experience courses. Augmented reality (AR) was incorporated into Business Orientation classes to increase student understanding of specialized business information resources. These activities helped librarians fulfill Houston Cole Library’s mission of creating a student-driven learning environment focusing on the Association of College Research Libraries (ACRL) information literacy framework. The research, planning, and implementation processes involved in the initiation of scavenger hunts, escape activities, and AR interactive stories at JSU have numerous applications across all educational levels and disciplinary focuses.

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Seegobin, Karan, Estela Staggs, Robina Khawaja, Satish Maharaj, Shiva Gautam, Carmen Smotherman, and Fauzia Rana. "Pilot study on the occurrence of multiple cancers following cancer-related therapy at the University of Florida, Jacksonville (2011–2016)." Journal of Investigative Medicine 66, no. 7 (June 6, 2018): 1050–54. http://dx.doi.org/10.1136/jim-2018-000772.

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New primary cancers can occur in patients with a previous cancer. Among the risk factors, therapies such as chemotherapy, radiotherapy, and hormonal therapy have been associated with the development of neoplasms. Second cancers most commonly develop 5–10 years after the initial tumor. We observe the implications of cancer-related therapy in the development of a new tumor. We looked at 602 patients who had their first cancer diagnosed in 2011 and calculated the number of different primary cancers between 2011 and 2016 for each patient. Twenty-four patients had a second cancer within 5 years from the first diagnosis and there were no patients with a third cancer. There was no statically significant difference in the rates of second cancers after exposure to chemotherapy, radiotherapy, hormonal therapy, or any combination of these (p=0.738). Of the second cancers reported after 2011, renal, uterine, cervical, and lung cancers were the most frequently reported. Additionally, there was no statically significant difference among the rates of second cancers in men versus women (p=0.467), as well as among whites versus blacks (p=0.318). We conclude that while new primaries can occur after one cancer, there was no increased risk after exposure to different cancer-related therapies. With increased focus on the primary disease, there is a higher likelihood of missing another primary lesion. This is important as the practical implications of managing multiple primaries are rarely discussed.

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Maksoud, Mohamed A., and Clifford B. Starr. "Implant Treatment in an Urban General Dentistry Residency Program: A 4-Year Retrospective Study." Journal of Oral Implantology 30, no. 6 (December 1, 2004): 364–68. http://dx.doi.org/10.1563/0.725.1.

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Abstract Little data have been published on the survival rates of implants placed in dental residency programs. This study reports on the outcome of dental implants placed by first-year general dentistry residents in the University of Florida College of Dentistry–Jacksonville Clinic. The patients for this study received both surgical and restorative implant therapy from 1998 to 2002. A total of 108 patients (62 women, 46 men) were treated with dental implants. On average, a patient was 52.9 years old and received 2.6 implants. A variety of simple and complex restorative procedures were performed. Advanced general dentistry residents in conjunction with supervisory faculty treated all cases. The cumulative implant survival was 98.2%. Follow-up varied from 6 months to 4 years after placement. Cases included implants not yet loaded as well as implants loaded for 3 years or more. The findings of this study compare favorably with published studies and were unexpected in light of the residents' limited clinical experience.

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Starr, Clifford B., and Mohamed A. Maksoud. "Implant Treatment in an Urban General Dentistry Residency Program: A 7-year Retrospective Study." Journal of Oral Implantology 32, no. 3 (June 1, 2006): 142–47. http://dx.doi.org/10.1563/807.1.

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Abstract Survival rates of multiple implant designs placed in various clinical situations average more than 90%. However, little data have been published on the survival rates of implants placed in dental residency programs. This study reports on the outcome of dental implants placed by first-year general dentistry residents in the University of Florida College of Dentistry–Jacksonville Clinic. The patients for this study received both surgical and restorative implant therapy from 1998 to 2005. A total of 263 patients (147 women, 116 men) were treated with dental implants. On average, a patient was 55.5 years old and received 3 implants. A variety of simple and complex restorative procedures were performed. Advanced general dentistry residents in conjunction with supervisory faculty treated all cases. The cumulative implant survival was 96.6%. Follow-up varied from 6 months to 7 years after placement. Cases included implants not yet loaded as well as implants loaded for 6 years or more. The findings of this study compare favorably with published studies and were unexpected in light of the residents' limited clinical experience.

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Kesler, Charles, and David Balch. "Development of a Telemedicine and Distance Learning Network in Rural Eastern North Carolina." Journal of Telemedicine and Telecare 1, no. 3 (September 1995): 178–82. http://dx.doi.org/10.1177/1357633x9500100308.

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A telemedicine service was established between the East Carolina University (ECU) School of Medicine in Greenville and the Central Prison in Raleigh, about 160 km away. Based on the first two years' experience of providing a prison telemedicine service, a medical education network was set up, linking the School of Medicine to health institutions in Ahoskie, approximately 160 km away, and Jacksonville, approximately 145 km away. At about the same time, a telemedicine network was installed linking the ECU to two rural hospitals, the Roanoke-Chowan Hospital in Ahoskie, and the Martin General Hospital in Williamston, both approximately 75 km away. Although it was a demonstration project, the prison telemedicine service was thought to be cost-effective. The cost of transporting a patient from prison for medical care was estimated to be $700. In comparison, a telemedicine consultation cost about $70, excluding the equipment and network costs. During the first 33 months of operation there were over 400 telemedicine consultations carried out in eastern North Carolina. The majority were dermatology consultations, with neurology and gastroenterology being next most frequent.

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Masood, Shahla. "Crossing the Borders: An International Breast Health Educational Initiative - A Collaboration Between the American Cancer Society and the University of Florida, Jacksonville." Breast Journal 14, no. 1 (January 2008): 1–2. http://dx.doi.org/10.1111/j.1524-4741.2007.00541.x.

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Seegobin, Karan, Estela G. Staggs, Robina Khawaja, Satish Maharaj, Shiva Gautam, Carmen Smotherman, and Fauzia N. Rana. "Does chemotherapy, radiotherapy, or hormonal therapy increase the risk of multiple cancers? A pilot study at University of Florida, Jacksonville—2011-2016." Journal of Clinical Oncology 36, no. 15_suppl (May 20, 2018): e13559-e13559. http://dx.doi.org/10.1200/jco.2018.36.15_suppl.e13559.

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Meyer, Ulrike, and Elke Schuch. "Diary-Writing as a Tool for Monitoring and Assessing - Intercultural Learning and Cultural Intelligence." European Journal of Language and Literature 7, no. 1 (January 21, 2017): 85. http://dx.doi.org/10.26417/ejls.v7i1.p85-95.

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This paper outlines a research project which is being conducted in the edu¬cational context of an international Master program: In 2001, an interdisci¬plinary and cohort-based Master program entitled “International Manage¬ment and Intercultural Communication/GlobalMBA” was founded, which is currently offered by a four-university consortium that includes the follow¬ing: Technische Hochschule Köln (TH Köln), Cologne, Germany, the Fac¬ulty of Management at the University of Warsaw (UW), Poland, Dongbei University of Finance and Economics (DUFE) in Dalian, China, and the Coggin College of Business at the University of North Florida (UNF) in Jacksonville, USA. During the program´s 15-month duration, a multina¬tional cohort of 25-30 students recruited from each of the four universi¬ties studies together for one semester at each university. Much of the coursework and assignments as well as the final Master thesis are written in multinational groups of three to four students, thus requiring the students to permanently prove their teamwork skills. Besides, given the in-built mobility and multinational cohort-based structure of the program, the students are continuously exposed to a variety of different cultural experi¬ences and encounters. The program´s curriculum includes management-oriented courses as well as courses on the theory and practice of intercul¬tural communication. In one of these latter modules called Applied Inter¬cultural Communication, which is taught in every location and has a strong country-specific perspective, students are required to produce reflective dia¬ries describing their cultural experiences. The research project presented here started in 2013 and is based on a qualitative analysis of students´ diary entries written during a time span of 15 months as part of the course requirements for this particular module. The project is intended to serve two main purposes:

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Trotter, Michael C. "Frank G. Slaughter, M.D., FACS: Medical Novelist and Surgeon Writer." American Surgeon 84, no. 12 (December 2018): 1841–46. http://dx.doi.org/10.1177/000313481808401225.

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“The curiosity of the public about things medical is probably greater than on any other single subject—except perhaps sex.” This quote by Frank Gill Slaughter, M.D., is indicative of the foresight, intuitiveness, and intelligence of one of the medical profession's most prolific and successful surgeon writers. His primary genre was historical fiction, and he incorporated medical and surgical history into nearly all of his writings with a “surgeon-hero” consistently the lead character. Slaughter published 65 books between 1941 and 1987 and sold 75 million copies in 23 languages. Slaughter received his medical degree from Johns Hopkins University in 1930 and completed general surgery training at Jefferson Hospital in Roanoke, Virginia, in 1934. He moved to Jacksonville, Florida, in 1934, where he would remain for the rest of his life, excepting military service in World War II. He became a Fellow of the American College of Surgeons in 1938 and was certified by the American Board of Surgery in 1940. Slaughter died in 2001 at the age of 93. This contribution examines the keen intellect and prolific authorship of this important and significant surgeon writer and medical novelist.

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Booth, Jonathon. "Robert Cassanello, To Render Invisible: Jim Crow and Public Life in New South Jacksonville. Gainesville: University Press of Florida, 2013. Pp. 188. Cloth $74.95." Journal of African American History 99, no. 3 (July 2014): 308–10. http://dx.doi.org/10.5323/jafriamerhist.99.3.0308.

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Taylor, Robert A. "To Render Invisible: Jim Crow and Public Space in New South Jacksonville. By Robert Cassanello. (Gainesville, FL: University Press of Florida, 2013. Pp. xv, 188. $74.95.)." Historian 77, no. 1 (March 1, 2015): 108–9. http://dx.doi.org/10.1111/hisn.12056_6.

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Schwartz, Denise B. "Hypoalbuminemia as an Indicator of Diarrheal Incidence in Critically Ill Patients R. BRINSON AND B. KOLTS Division of Gastroenterology and Nutrition, Department of Internal Medicine, University of Florida College of Medicine, University Hospital, Jacksonville, Florida." Nutrition in Clinical Practice 2, no. 5 (October 1987): 216–17. http://dx.doi.org/10.1177/088453368700200511.

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PRINCE, K. STEPHEN. "Robert Cassanello, To Render Invisible: Jim Crow and Public Life in New South Jacksonville (Gainesville: University Press of Florida, 2013, $74.95). Pp. 192. isbn978 0 8130 4419 4." Journal of American Studies 48, no. 3 (July 11, 2014): 887–88. http://dx.doi.org/10.1017/s0021875814001091.

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Best, Kelly A., Brent E. Seibel, and Deborah S. Lyon. "Grommets and Glue Guns: Standardization of a Pfannenstiel Model for Low-Fidelity Obstetrics-Gynecology Education." Journal of Graduate Medical Education 1, no. 2 (December 1, 2009): 264–68. http://dx.doi.org/10.4300/jgme-d-09-00038.1.

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Abstract Objective To validate standardized instructions for the creation, implementation, and performance assessment of a low-fidelity model for Pfannenstiel incision. Study Design The Pfannenstiel model used at the University of Florida-Jacksonville was broken down into composite steps and constructed by obstetrics-gynecology faculty from across the country. The model was then utilized at participants' home institutions and evaluated with respect to realism of the model, ability to replicate the simulation, appropriateness of the skills checklists, and perceived utility of a publication of similarly catalogued simulation modules for use in obstetrics-gynecology training programs. Results The model was correctly constructed by 94.7% (18 of 19) participants and 72.2% (13 of 18) completed a post construction/post simulation survey indicating a high degree of perceived educational utility, feasibility of construction, and desire for additional catalogued modules. Conclusions A low-fidelity simulation model was developed, successfully reproduced using inexpensive materials, and implemented across multiple training programs. This model can serve as a template for developing, standardizing and cataloging other low-fidelity simulations for use in resident education. As discussions among medical educators continue regarding further restrictions on duty hours, it is highly likely that more programs will be looking for guidance in establishing quick, inexpensive, and reliable means of developing and assessing surgical skills in their learners. Furthermore, the Accreditation Council for Graduate Medical Education (ACGME) has well-defined goals of programs developing better and more reproducible tools for all of their assessments. For programs with limited resources, preparing and disseminating reproducible, validated tools could be invaluable in complying with future ACGME mandates.

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James, Hector E. "Pediatric neurosurgery telemedicine clinics: a model to provide care to geographically underserved areas of the United States and its territories." Journal of Neurosurgery: Pediatrics 18, no. 6 (December 2016): 753–57. http://dx.doi.org/10.3171/2016.6.peds16202.

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OBJECTIVE The author describes the creation, structuring, and development of a pediatric neurosurgery telemedicine clinic (TMC) to provide telehealth across geographical, time, social, and cultural barriers. METHODS In July 2009 the University of Florida (UF) Division of Pediatric Neurosurgery received a request from the Southeast Georgia Health District (Area 9–2) to provide a TMC to meet regional needs. The Children's Medical Services (CMS) of the State of Georgia installed telemedicine equipment and site-to-site connectivity. Audiovisual connectivity was performed in the UF Pediatric Neurosurgery office, maintaining privacy and HIPAA (Health Insurance Portability and Accountability Act) requirements. Administrative steps were taken with documentation of onsite training of the secretarial and nursing personnel of the CMS clinic. Patient preregistration and documentation were performed as required by the UF College of Medicine–Jacksonville. Monthly clinics are held with the CMS nursing personnel presenting the pertinent clinical history and findings to the pediatric neurosurgeon in the presence of the patient/parents. Physical findings and diagnostic studies are discussed, and management decisions are made. RESULTS The first TMC was held in August 2011. A total of 40 TMC sessions have been held through January 2016, with a total of 43 patients seen: 13 patients once; 13 patients twice; 8 patients for 3 visits; 2 for 4 visits; 2 for 6 visits; 2 for 5 visits; 2 for 7 visits; and 1 patient has been seen 8 times. CONCLUSIONS Pediatric patients in areas of the continental US and its territories with limited access to pediatric neurosurgery services could benefit from this model, if other pediatric neurosurgery centers provide telehealth services.

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WILLIS, K. "$16.95 pbkC Gutmann Mathew, The Meanings of Macho: Being a Man in Mexico City, University of California Press, Gainesville Tallahassee Tampa Boca Raton Pensacola Orlando Miami Jacksonville (1996), p. xvi + 330." Bulletin of Latin American Research 17, no. 2 (May 1998): 243–45. http://dx.doi.org/10.1016/s0261-3050(97)00096-x.

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Hook, Andrew. "Brantley, R. E., Coordinates of Anglo-American Romanticism, Wesley, Edwards, Carlyle and Emerson. Pp. xi + 207. Gainesville, Tallahassee, Tampa, Boca Raton, Pensacola, Orlando, Miami, Jacksonville: University Press of Florida, 1993. £26.95." Notes and Queries 42, no. 2 (June 1, 1995): 252–53. http://dx.doi.org/10.1093/notesj/42.2.252.

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Schwartz, Denise B. "Diarrhea Associated with Severe Hypoalbuminemia : A Comparison of a Peptide-Based Chemically Defined Diet and Standard Enteral Alimentation R. BRINSON AND B. KOLTS Division of Gastroenterology and Nutrition, Department of Internal Medicine, University of Florida College ofmedicine, University Hospital, Jacksonville, Florida." Nutrition in Clinical Practice 3, no. 4 (August 1988): 157–58. http://dx.doi.org/10.1177/088453368800300410.

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Minocha, Vinay Nikhil, Carmen Smotherman, Jason Desmond Hew, and Dat C. Pham. "The impact of race and insurance status on survival of patients with non-small cell lung cancer." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): e18064-e18064. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e18064.

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e18064 Background: Previous studies have demonstrated disparities in survival outcomes between black and white patients with lung cancer. Black patients are more likely than white patients to have no health insurance or insufficient coverage which may limit their access to treatment. The purpose of this study was to determine the impact of race and insurance status of patients with non-small cell lung cancer on survival outcomes at our institution. Methods: Our study included patients diagnosed and treated for non-small cell lung cancer from 2005 through 2015 at University of Florida hospital in Jacksonville. Cox proportional hazard models were used to study the effect of race (black vs white), insurance, age, tobacco use, family history of cancer and stage on hazard rates for mortality. Time to treatment was compared between blacks and whites using the non-parametric Wilcoxon rank sum test. Results: Of the 1301 patients in our study, 445 (34%) were black. More black patients had Medicaid (24% vs 18%, p = 0.01), and were diagnosed at stage III or IV (81% vs 75%, p = 0.01) compared to white patients. Black patients had higher death rates compared to white patients (80% vs. 71%, p < .0004). Adjusting for stage and insurance, black patients had higher hazard rates for mortality than white patients (HR = 1.18, 95%CI 1.03, 1.35, p = 0.02). Patients with Medicaid and Medicare without supplement had higher hazard rates for mortality compared to other insurance categories (Table). There was no significant difference in time to treatment amongst patients of different races (p = 0.38) and insurance types (p = 0.54). Conclusions: Our study reveals worse survival outcomes in black patients compared to white patients with non-small cell lung cancer, controlling for insurance status and stage at presentation. Future research is needed to determine whether other factors may explain these racial disparities. [Table: see text]

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Shah, MD, Nipa R., Judella Haddad-Lacle, MD, and Thanh Hogan, Pharm-D. "Successful interventions in decreasing oxycodone CR prescriptions within an underserved population." Journal of Opioid Management 11, no. 6 (November 1, 2015): 481. http://dx.doi.org/10.5055/jom.2015.0301.

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Objective: To use fundamental population health and Patient Centered Medical Home guidelines to create an effective intervention that would decrease the quantity of inappropriate oxycodone controlled release (CR) prescriptions within an uninsured population.Design: This was a prospective interventional study.Patients, participants: Patients seen in the newly formed University of Florida Community Health and Family Medicine Department Total Care Clinic, for chronic nonmalignant pain. This clinic was designed to serve the uninsured patients of Jacksonville, FL.Interventions: A structured, step-wise pain management protocol was introduced and implemented, and an improved Controlled Substance User Agreement was created and implemented. Pharmacists and primary care providers collaborated on care.Main outcome measure(s): The primary study outcome measures were the number of oxycodone CR prescriptions over an 8-month period.Results: At the initiation of the program, the authors averaged over 40 oxycodone CR prescriptions per month. After 3 months, the number of prescriptions dropped to an average of 10 per month, a 75 percent decrease. More importantly, the number of oxycodone CR tablets saw a corresponding 75 percent drop from over 2,500 tablets per month to approximately 600 per month. Of course, the authors were concerned that the reduction of oxycodone CR may lead to increases in the use of other opioids. However, trends for hydrocodone/acetaminophen also showed a reduction in total usage as well as all other long-acting opioids. In addition, patient satisfaction did not change significantly, and no significant complaints from patients regarding this specific change were received.Conclusions: By implementing criteria for oxycodone CR prescribing in an innovative, comprehensive, and unified patient-centered practice model, the authors saw a significant decrease in the number of oxycodone CR tablets prescribed per month and also a decrease in total prescriptions per month.

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Wright, James D. "Keynote Address, Annual Meeting of the Association for Applied and Clinical Sociology October 17, 2008, Jacksonville, Florida: Ten Reasons Why University-Community Partnerships Turn Sour and Some Thoughts on How to Avoid Them." Journal of Applied Social Science 3, no. 1 (March 2009): 7–17. http://dx.doi.org/10.1177/193672440900300102.

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LUFT, PAUL. "MOHAMMAD GHOLI MAJD: Great Britain and Reza Shah: the plunder of Iran, 1921–1941. xiii, 429 pp. Gainsville/Tallahassee/Tampa/Boca Raton/Pensacola/Orlanda/Miami/Jacksonville/Ft. Myers: University Press of Florida, 2001. £49.50." Bulletin of the School of Oriental and African Studies 67, no. 1 (February 2004): 93–95. http://dx.doi.org/10.1017/s0041977x0424006x.

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Thompson, Wesley, Naeem Latif, and Robert Rahberg. "Why African Americans are more predisposed to pancreatic cancer: Nature versus nurture." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): e15018-e15018. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15018.

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e15018 Background: There are known risk factors for pancreatic cancer like diabetes mellitus; cigarette smoking; poverty, and alcoholism; all of which are more common in African American patients than the general population. The purpose was to determine if these established risk factors were more associated within African American pancreatic cancer patients to explain their 50 – 90% increased incidence in the U.S. population. Methods: This retrospective study reviewed 172 biopsy-proven pancreatic cancer patients diagnosed over ten years at University of Florida Jacksonville. We employed linear regression models to determine statistical significance of established risk factors with prevalence of pancreatic cancer among cohorts. Results: Our data showed no increased association of diabetes, tobacco use, alcohol use between African Americans and Caucasians. However, Africans Americans as a group were twice as likely to be found at stage III or IV upon diagnosis, conferring an increased mortality risk (OR = 2.2, (95% CI 1.1 – 4.39)). Among these African Americans at advanced stage of diagnosis, females were at triple risk by odds ratio to be underinsured compared to Caucasian males (OR = 3.1, (95% CI 1.29 – 7.49, p = 0.015)). African American females were almost twice as likely to be underinsured compared to Caucasian females (OR = 1.72, (95% CI 0.646, 4.558)). The lack of healthcare access maybe related to advanced stage at diagnosis and its increased mortality risk. Conclusions: Our data suggests that the risk factors of smoking, alcoholism, and diabetes mellitus alone do not explain African Americans’ propensity for pancreatic cancer. However, lack of health insurance does confer an advanced stage at diagnosis and increased mortality risk among African American females. Our data also suggests that other etiological factors such as genetics maybe be associated with the increased risk amongst African Americans. A further investigation is warranted into genetic etiologies since African American patients have higher incidence of K-ras mutations than Caucasians; and mutated K-ras has been associated with pancreatic cancer, which is a target for therapy.

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NK, Sunčana. "Occurrence of Pancreatic Cancer Associated Insulin Dependent Diabetes." Cancer Research and Cellular Therapeutics 1, no. 3 (September 8, 2017): 01–03. http://dx.doi.org/10.31579/2640-1053/016.

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Patients with pancreatic cancer often present with non-specific symptoms and are often diagnosed at an advanced stage. The relationship between diabetes and the development of pancreatic cancer has been an area of intense research. In the present study we specifically aim to look at the hypothesis that the incidence of insulin dependent diabetes increases after the onset of pancreatic cancer. Materials and Methods: We retrospectively reviewed the chart of all pancreatic cancer patients in tumor registry admitted to University of Florida Tumor Registry in Jacksonville, Florida. Data was collective from January 2000 and December 2006. Each patient’s record was reviewed for histologic biopsy, demographic information, presence of risk factors, co-morbidities, presence and duration of diabetes. Assessment of diabetes was based on the guidelines provided by American Diabetes Association. Results: 82 patients were identified from the University of Florida Cancer Registry from the year 2000-2006. Complete data was available on 76 patients. Mean age at diagnosis was 66.4 years. 53 (69.7%) were African American, 23 (30.26%) were white. There was an equal male/female distribution of 1:1.07 (43 males; 40 females). 35 (46.0%) patients were smokers. Most common presentation was with obstructive jaundice (33/76 or 43.4%) followed by typical symptoms of weight loss, fatigue, abdominal and back pain (31/76 or 40.78%). In 11 (14.47%) patients, pancreatic cancer was noted as an incidental finding. Staging at the time of diagnosis was available in 76 patients. 48 (63.1%) patients were in Stage 4, 13 (17.1%) patients were in Stage 3, 10 (13.15%) patients were at stage 2 and 5 (6.5%) patients were in Stage 1. 15(19.7%) patients had diabetes at the time of diagnosis of pancreatic cancer. 5 (6.5%) developed one or more deep vein thrombosis (DVTs) after the diagnosis of PC. Diabetes was present in 15 (19.7%) for an average duration of 19 months. Only 4(26.6%) out of 15 patients were on insulin therapy before the diagnosis of pancreatic cancer. Six additional patients (an increase of 7.93%) developed diabetes after the diagnosis of pancreatic cancer. 13 (61.9%) of the 21 patients required insulin therapy after the diagnosis of pancreatic cancer. As many as 27 (35%) patients opted for hospice care after the diagnosis of pancreatic cancer. Whipple’s procedure or exploratory debulking surgery of the tumor was performed in 33 (43%) patients. 29 (38.1%) patients received Gemcitabine/carboplatin/5 FU based chemotherapy. Conclusion: We found that the Incidence of Insulin-dependent diabetes increased in patients diagnosed with pancreatic cancer.

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Nichols, Romaine Charles, Christopher G. Morris, Robert Anthony Zaiden, Ziad Awad, Rovel Colaco, Bradford S. Hoppe, William M. Mendenhall, and Nancy Price Mendenhall. "Presenting characteristics of insured and uninsured patients with anorectal malignancy referred for radiotherapy at an urban safety net hospital." Journal of Clinical Oncology 31, no. 4_suppl (February 1, 2013): 363. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.363.

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363 Background: This retrospective study compares: presenting characteristics; time intervals between symptom emergence, tissue diagnosis and initiation of therapy; and survival, for insured (IP) and uninsured patients (UP) with anal (22) or rectal (39) malignancy referred for radiotherapy at University of Florida Shands Hospital in Jacksonville. Methods: From 5/2002 to 8/2012, 63 newly diagnosed patients were evaluated. 2 patients were excluded due to mental illness. Records were reviewed to capture: 1.) Patient demographics; 2.) Stage at diagnosis; 3.) Weight loss at diagnosis; 4.) Patient reported date of symptom onset; 5.) Date of tissue confirmation of malignancy; 6.) Date of first therapeutic intervention (i.e. surgery, chemotherapy or radiotherapy); 7.) Insurance status at each of the above time points; and 8.) Survival data. Results: At the time of symptom emergence, 32 patients were uninsured and 29 were insured. Median age of UP was 52 years vs. 64 years for IP (P=0.0005). UP experienced median intervals of 258.5 days between symptom emergence and tissue confirmation of malignancy vs. 58 days for IP (P=0.0013). UP experienced median intervals of 314.5 days between symptom emergence and treatment initiation vs. 120 days for IP (P=0.0024). UP presented with T4 primary tumors in 41% of cases vs. 7% for IP (P=0.0027). UP presented with a median weight loss of 10 lbs vs. 0 lbs for IP (P=0.0158). UP presented with lymph node metastasis in 66% of cases vs. 45% for IP (P=0.1264). With a median follow up of 22 months for UP and 32 months for IP, 2 year actuarial overall survival was 87% for UP and 74% for IP (P=0.5503). Conclusions: UP presented at a younger age than IP (P=0.0005) and demonstrated:1.) Longer intervals between symptom emergence and tissue confirmation of malignancy (P=0.0013); 2.) Longer intervals between symptom emergence and treatment initiation (P=0.0024); 3.) Greater likelihood of presenting with a T4 tumor (P=0.0027); 4.) Greater weight loss at presentation (P=0.0158); 5.) A trend toward a greater likelihood of presenting with lymph node metastasis (P=0.1264); 6.) No difference in actuarial 2 year survival from date of diagnosis compared to IP. (P=0.54).

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Lamers, Susanna, David Nolan, Yvette Simone McCarter, Chad Neilsen, Rebecca Rose, Christopher Rodriguez, and Stephanie Cross. "Using Whole-Genome Sequencing to Improve Surveillance Measures: Case Study of Methicillin-Resistant Staphylococcus aureus (MRSA) in a Florida Hospital." Infection Control & Hospital Epidemiology 41, S1 (October 2020): s505—s506. http://dx.doi.org/10.1017/ice.2020.1186.

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Background: The CDC considers methicillin-resistant Staphylococcus aureus (MRSA) one of the most important hospital-acquired infections (HAIs) in the United States. However, infection control departments (ICDs) often rely on subjective data to determine whether multiple MRSA cases are a true outbreak and whether the hospital is responsible (community- vs hospital-acquired). Objective: Our objective was to determine whether whole-genome sequencing (WGS) of MRSA provided new insights into on transmission dynamics at large, inner-city hospital in Jacksonville, Florida. Methods: Over a 4-month period, MRSA samples were obtained from 44 infected patients at 3 campuses within a single hospital system. Limited nonpatient identifying information was obtained, including date of collection, campus, unit, reason for admission, and days post admission (DPA) of MRSA diagnosis. Whole-genome sequences were generated using the Illumina platform. Raw reads were processed, and genetic distances were calculated and used to identify genetically linked bacterial infections using FoxSeq version 1.0 software. Results: Based on their length of stay, 10 patients were reported by the ICD as obtaining an HAI. Three distinct “episodes” were evident in which >5 MRSA cases were observed within a 3–5-day period. Genomic analysis identified 5 clusters of linked infections: 4 clusters contained 2 patients and another contained 3. Of these clusters, only 1 contained multiple cases that were reported as HAIs; however, because these case were separated by 2 weeks, it is unlikely that they came from a source in the hospital. The results suggest that HAIs were overreported and that most MRSA present in the hospital likely came from community sources. Conclusions: WGS provided clear evidence that temporally clustered MRSA cases do not imply an outbreak is occurring. Furthermore, ongoing detection of the same community-acquired infections over several months is indicative of a shared source outside of the hospital, which could be uncovered through examination of clinical records. Considering the implications of HAIs, best approaches to combat them should include identifying their sources. As molecular surveillance approaches to infection control are rapidly becoming easier and less expensive, the methods can be used to bring objective clarity to the ICD.Funding: NoneDisclosures: Susanna L. Lamers reports salary from BioInfoExperts and contract research for the NIH, the University of California - San Francisco, and UMASS Medical School.

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Mizrahi, Jonathan, Valerie Gunchick, Kabir Mody, Lianchun Xiao, Phani Keerthi Surapaneni, Rachna T. Shroff, and Vaibhav Sahai. "FOLFIRI in advanced biliary tract cancers." Journal of Clinical Oncology 37, no. 4_suppl (February 1, 2019): 451. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.451.

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451 Background: Gemcitabine plus platinum (GP) is the standard of care first-line treatment for advanced biliary tract cancers (BTC). There is no established second-line therapy, and retrospective reviews report progression-free survival (PFS) for second-line treatment to be < 3 months. 5-Fluorouracil plus irinotecan (FOLFIRI) is a commonly used regimen in patients (pts) with BTC who have progressed on GP, though there is a paucity of data regarding its efficacy in this population. Methods: We retrospectively evaluated pts with advanced BTC who were treated with FOLFIRI at MD Anderson, University of Michigan and Mayo Clinic in Jacksonville. Data were obtained on pt demographics, type of BTC, PFS, and overall survival (OS). Results: Ninety-eight pts were included of which 74 (76%) had metastatic disease at the time of treatment with FOLFIRI. The median age was 59 (range, 22 to 86) years. The number of pts with extrahepatic cholangiocarcinoma (CCA)/gall bladder (GB)/intrahepatic CCA were 10, 17, and 71. FOLFIRI was used as 1st, 2nd, 3rd or 4th – Nth lines in 8, 50, 36, and 4 pts, respectively. Of the 65 pts whose best responses were documented, 23 (35%) had stable disease and 7 (11%) had a partial response per RECIST v1.1. Median duration on FOLFIRI was 2.2 months. The median PFS and OS were 2.4 (95% CI 1.7 to 3.1) and 6.6 (95% CI 4.7 to 8.4) months, respectively. Median PFS for pts treated with FOLFIRI in 1st, 2nd, 3rd or 4th – Nth lines were 3.1, 2.5, 2.3 and 1.5 months, respectively. Eighteen pts received concurrent bevacizumab (13) or EGFR-targeted therapy (5) with FOLFIRI, and both of groups exhibited a median PFS of 2.7 months. Eastern Cooperative Oncology Group performance status (PS) of 0-1 was associated with improved OS (P = 0.006) compared to PS of 2-3. Conclusions: In this multi-institution retrospective review of 98 pts with BTC treated with FOLFIRI, efficacy of this regimen appears to be modest. While PFS and OS outcomes were similar to what has been previously reported, the 46% disease control rate in this group of predominantly pretreated pts is encouraging. Given the lack of other standard therapies, FOLFIRI may still have a role in this pt population, but these results emphasize the need for more effective treatment options for pts with advanced, pretreated BTC.

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Reza, Mohammed, Eran Magen, Naheed Vora, Katherine Rogers, Debbie Moll, Elaine Warren, Anil Suryaprasad, Laura Armas-Kolostroubis, and Alice Cheung. "LB-14. CovidIQ- a Text Message-Based Symptom Surveillance Tracker that Predicts New Areas of Increased Incidence of Covid-19 Disease." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S850—S851. http://dx.doi.org/10.1093/ofid/ofaa515.1911.

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Abstract Background Testing for SARS-CoV-2 is limited, making it difficult to estimate the true prevalence of disease and control the spread of new cases. Therefore, finding other ways to diagnose new cases of Covid-19 early is essential for preventing further spread of SARS-CoV-2 to other people in the community and prevent further outbreaks from occurring. Methods CovidIQ is a confidential and secure text messaging platform that works by collecting participants’ self-reported symptoms. Upon agreeing to participate, users are asked some basic demographic questions including gender, age range, ethnic background, and zip code. Participants are then queried via text message on a weekly or biweekly basis as to what symptoms they are experiencing: none, temperature >99.6F, cough, shortness of breath, headache, fatigue, loss of appetite, loss of sense of smell or taste, diarrhea, body ache, sore throat, and/or chills. The symptoms are further broken down into major and minor criteria, allowing presumptive cases to be identified with more accuracy. The major criteria include elevated body temperature, cough, and shortness of breath. If a participant has any 2 major criteria, 1 major or 2 minor, or 3 minor criteria, they are considered a presumptive positive case. While CovidIQ cannot be used to diagnose individuals, the combined results from many individuals show real-time changes in rates of infection for entire counties. Not all people who develop Covid-19 will need hospitalization. They may remain out in the community unaware of the risk they pose to others. And, because the official count of confirmed cases is delayed by 2–4 weeks from the time of actual infection, CovidIQ can sound the alarm much earlier when rates of infection begin to spike. Advanced warning can help communities and individuals make informed decisions about how they should conduct themselves. Results CovidIQ identified the spike in COVID-19 cases in Jacksonville/Duval County, Florida a full two weeks before it was reported by the Florida Department of Health and Johns Hopkins University. Prevalence of Suspected COVID-19 Cases Through the Use of the CovidIQ Platform in Relation to Dates of OfficiallyReported Cases, Duval County, FL Conclusion CovidIQ is a novel tool developed to augment the public health response to this ongoing crisis by informing the public sector of potential new hot spots before areas experience a surge as compared to the current reporting structure. Disclosures All Authors: No reported disclosures

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Dispenzieri, Angela, Matthew J. Loe, Susan M. Geyer, Jacob B. Allred, James Olen Armitage, John K. Camoriano, Ahmet Dogan, David M. Menke, and Thomas M. Habermann. "A Prognostic Model of 114 Patients with Castleman’s Disease." Blood 108, no. 11 (November 16, 2006): 102. http://dx.doi.org/10.1182/blood.v108.11.102.102.

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Abstract Background: Castleman Disease (angiofollicular hyperplasia) is a rare, lymphoproliferative disease. There has been no large study describing the natural history of this disease. Hypothesis: A retrospective analysis of clinical, pathologic, and laboratory factors predictive of outcome should be identifiable. Methods: During the period from 3/30/48 to 6/18/2002, 114 patients with Castleman Disease were seen at the Mayo Clinic (Rochester, 56; Jacksonville, 19; Arizona, 13) and at the University of Nebraska (26). Pathology, laboratory and clinical characteristics analyzed included: the presence of unicentric or multicentric disease, the pathologic variant (hyaline vascular versus plasma cell variant), co-existing POEMS syndrome, age, serum albumin, alkaline phosphatase, AST, sedimentation rate, the presence of cytopenias, organomegaly (hepatomegaly or splenomegaly), papilledema, peripheral neuropathy, sclerotic bone lesions, renal disease, B-symptoms or respiratory symptoms. The impact of these variables on overall survival from time of diagnosis was evaluated using univariate analyses, where their significance was determined based on the logrank statistic. To derive the multivariable model, the score-based model-building method was used. Based on this approach, a 3-variable model was designed, adjusting for age at diagnosis. Patients were then assigned a risk score corresponding to how many of these risk factors they possessed. A final proportional hazards model was constructed based on this risk score. Results: The median age at diagnosis was 43 (range: 5 – 78), and 48% of patients were male. Fifty-five patients had multicentric disease. Median follow-up of living patients was 5.8 years (range: 0.02 – 27). On univariate analysis, factors that predicted for overall survival included: age at diagnosis, presence of multicentric disease, presence of a monoclonal protein in the urine, co-existing POEMS syndrome, serum albumin, presence of cytopenias, organomegaly, neuropathy, thrombocytosis, and respiratory symptoms. The final multivariable model included 98 patients. Adjusting for age, the model included organomegaly, respiratory symptoms, and thrombocytosis. Patients were assigned 1 point for each risk factor they possessed based on clinical relevance and similarity of the hazard ratios for each of these 3 variables (ranging from 3.1 to 4). A final prognostic survival model was constructed using this assigned risk score. These scores were collapsed further based on observed similarities (0 factors vs. 1 or more factors). This final model yielded a hazards ratio of 5.5 (95% CI 2.3–13.4). The 10 year survival rates were 80% (95% CI: 65–98%) and 41% (95% CI: 28–59%) for the 0 factor and 1+ factor groups, respectively. The 20 year survival rates were 71% (95% CI: 52–87%) and 31% (95% CI: 19–51%), respectively. Conclusion: The most distinguishing prognostic clinical, laboratory, and pathological characteristics of Castleman’s Disease are orgnaomegaly, respiratory symptoms, and thrombocytosis. This prognostic scoring system should aid in individual cases and in assessing results of therapeutic interventions.

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Maharaj, Satish, Simone Chang, Karan Seegobin, Marwan Shaikh, and Vivek R. Sharma. "Hematologic Effects Following Crotalinae and Unknown Snake Bites in Northeast Florida." Blood 136, Supplement 1 (November 5, 2020): 1. http://dx.doi.org/10.1182/blood-2020-143449.

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Background: Approximately 5000 snake bites are reported in the United States (US) annually with half of these patients being admitted. Crotalinae species are the most numerous; coral and imported exotic snakes cause a smaller number. Snake venoms are highly stable chemically complex mixtures of proteins. Quantity and composition vary with species and geographic location. Although enzymes contribute to the deleterious effects of the venom, the lethal components may be the smaller low molecular-weight polypeptides. Crotalinae envenomation is known to contain thrombin-like glycoproteins that can induce coagulopathy ranging from asymptomatic lab abnormality to disseminated intravascular coagulopathy (DIC) and life-threatening hemorrhage. In certain geographical areas of the United States thrombocytopenia, hypofibrinogenemia and coagulopathy are common hematological abnormalities, and ones that dictate both a reason for treatment with antivenom as well as an important monitor of therapeutic efficacy. Data on hematological abnormalities following envenomation by crotaline species in Northeast Florida/Southwest Georgia has not been reported before. Methods: We conducted a retrospective review of envenomations that presented to the University of Florida at Jacksonville from April 2013 to October 2018. Patients had to be 16 years or older without any pre-existing hematologic disorder or use of anticoagulant medications. Data including Complete Blood Count, Prothrombin Time (PT), activated Partial Thromboplastin Time (aPTT) and Fibrinogen were measured on presentation, and 4 hours after. Crotaline Fab antivenom (CroFab®) administration was noted if done. Adverse events associated with antivenom therapy, recurrence phenomena, delayed onset of symptoms, and performance of fasciotomy were also recorded. Results: Overall, 119 snakebites were evaluated. The majority were identified as Crotalinae - 25 water moccasin, copperhead or cottonmouth (Agkistrodon piscivorus, Agkistrodon contortrix) bites and 34 rattlesnake (Sistrurus miliarius, Crotalus adamanteus) bites. Male sex dominated the sample with most patients middle-aged (Table 1). More than 80% of patients arrived within 6 hours following the bite. Over 60% of patients received crotaline Fab antivenom. Results are presented in Table 2. Around 12% of patients with water moccasin, copperhead or cottonmouth (Agkistrodon piscivorus, Agkistrodon contortrix) bites had coagulopathy on admission. This compares similarly to data from South Carolina previously showing a 10.89% rate following copperhead bites (Qureshi et al. Blood 2010;116(21):4753). The rate of coagulopathy with rattlesnake bites was however much higher in North Florida at 20.6% - compared to 5.26% in the South Carolina series. Rates of DIC or severe hemorrhage were 8% for water moccasin, copperhead or cottonmouth (Agkistrodon piscivorus, Agkistrodon contortrix) bites and 5.9% for rattlesnake (Sistrurus miliarius, Crotalus adamanteus) bites. When hemostatic defects were looked at separately, the most common abnormality induced was PT/aPTT derangement, followed by hypofibrinogenemia and then thrombocytopenia. This pattern was the same as reported in South Carolina. Recurrence phenomena was observed after 4 hours in a number of patients, however the significance of this remains uncertain as most of these patients remained clinically stable without worsening symptoms. Anaphylactic reaction to the antivenom developed in one patient. Conclusions: In this sample from North Florida, deranged PT/aPTT was the most common hematologic abnormality following envenomation, followed by hypofibrinogenemia and a low rate of thrombocytopenia. Similarities with data from South Carolina were noted, although rattlesnake bites had 4 times higher incidence of coagulopathy in North Florida. DIC or severe hemorrhage was a notable toxicity, affecting 6-8% of Crotalinae cases. Hematologic effects of envenomation do seem to vary by geographic areas in the United States and physicians would benefit from local data to better manage these patients. Disclosures No relevant conflicts of interest to declare.

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Grubb, Gary S., Julia D. Welch, Lynda Cole, Alfredo Goldsmith, and Roberto Rivera. "A comparative evaluation of the safety and contraceptive effectiveness of 65 mg and 100 mg of 90-day norethindrone (NET) injectable microspheres: a multicenter study**Partial support for this study was provided by the Program for Applied Research in Fertility Regulation (PARFR) and by Family Health International (FHI) with funds from the U.S. Agency for International Development (USAID), although the views expressed in this article do not necessarily reflect those of USAID.††The investigators and centers participating in this study were David Archer, M.D., University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (currently Director of Clinical Research, Contraceptive Research and Development Program, Norfolk, Virginia); Guiseppe Benagiano, M.D., Associazione per Studio della Riproduzione Umana Rome, Italy; Horacio Croxatto, M.D., Instituto Chileno de Medicini Reproductiva, Santiago, Chile; Jerome Hoffman, M.D., Mount Sinai Medical Center, Miami Beach, Florida; Andrew Kaunitz, M.D., University Hospital of Jacksonville, Jacksonville, Florida; Roberto Rivera, M.D., Instituto de Investigacion Cientifica, Durango, Mexico (currently Director of Clinical Trials, Family Health International, Research Triangle Park, North Carolina); Mukul Singh, M.D., The New York Hospital-Cornell University Medical Center, New York, New York; and Howard Tatum, M.D., Emory University School of Medicine, Atlanta, Georgia." Fertility and Sterility 51, no. 5 (May 1989): 803–10. http://dx.doi.org/10.1016/s0015-0282(16)60670-2.

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Chiong, Charlotte M. "Combined Electric and Acoustic Stimulation: Successful Treatment Option for Partial Deafness." Philippine Journal of Otolaryngology-Head and Neck Surgery 25, no. 2 (December 3, 2010): 52–56. http://dx.doi.org/10.32412/pjohns.v25i2.641.

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Cochlear implants are now the treatment of choice for patients with severe to profound hearing loss. Inclusion criteria for cochlear implantation have expanded, and a whole array of implantable hearing devices have been introduced over the years. To date, more than 250 cochlear implantations have now been performed in the Philippines (Figure 1). In 2006, the first auditory brainstem implantation, and first vibroplasty or middle ear implantation in the country were done at the Philippine General Hospital (PGH). In 2008, the first electroacoustic stimulation or partial deafness cochlear implantation surgery in the country was performed at the Capitol Medical Center by Professor Joachim Müeller of the University of Würzburg and the author. This concept, that cochlear implantation can be performed for patients with residual hearing or only partial deafness, is quite novel. There are patients whose low frequency hearing below 1.5 kHz is still be quite good while high frequency hearing loss above 1.5 kHz is in the severe to profound range (Figure 2). For such patients speech discrimination scores will typically fall below 60% at 65 dB sound pressure level (SPL) in the best aided condition. This technological advancement, often called electroacoustic stimulation (EAS), was developed in 1999 after Christoph Von Ilberg demonstrated preserved residual low frequency hearing in a patient who underwent cochlear implantation such that the patient wore a hearing aid in the implanted ear.1 Currently, EAS devices are available from two manufacturers. Contraindications to the use of EAS are shown in Table 1. Candidates for EAS devices should have stable low frequency hearing. There should be no progressive or autoimmune sensorineural hearing loss. Also there should be no history of meningitis, otosclerosis, or any other malformation that might cause an obstruction. The patient’s air-bone gap should be < 15 dB. Finally, there should not be any external auditory canal problems that can impede placement of the ear mould for the acoustic component. There are two main components of the EAS system (Figure 3). The external component is made up of a microphone that picks up sounds and a processor that separately encodes low and high frequency energy. After processing, low frequency energy is converted into an acoustic signal via the loudspeaker located in the ear hook and delivered into the external auditory canal. This acoustic signal will vibrate the tympanic membrane and ossicles so that cochlear fluids as well as the relatively intact structures of the cochlea in the apical region are stimulated. In contrast, high frequency energy is coded into radio-wave-like signals which are transmitted transcutaneously to the internal receiver. There, electric signals are delivered to the electrode array that has been surgically implanted into the cochlea. Thus the auditory nerve receives information using two different pathways from low and high frequency sounds, and the auditory nerve signals are then transmitted to the brain. Our Experience: Of the more than 100 implantations done under the Philippine National Ear Institute “CHIP” or Cochlear and Hearing Implants Programme only one was a case of EAS implantation. This particular case demonstrates key principles and concepts that every otolaryngologist should consider. Among these are audiological evaluation, temporal bone imaging, surgical technique for hearing preservation and some quality of life issues. Audiological Evaluation A 33 year old man had been seen at the clinic for over 7 years, with serial audiograms (Figure 4-6) illustrating the presence of good and stable low frequency hearing while high frequency hearing loss increased somewhat. The patient had been continually advised to get the best hearing aids available. However, a series of high-end hearing aids did not solve his problem of poor hearing in noisy places nor his difficulty understanding words when watching television and movies. Figure 7A shows the speech perception scores of this patient obtained with a Word Intelligibility by Picture Identification (WIPI) test, a “closed-set test” using isolated words while Figure 7B represents speech scores when “open-set” Bamford-Kowal-Bench (BKB) Sentence Lists were presented to the listener in both quiet and noise prior to the implantation. Temporal bone imaging A combination of high resolution computerized tomography (HRCT) of the temporal bone with both coronal and axial cochlear views, and T2-weighted normal anatomic Fast Spin Echo (T2 FSE) or 3D Constructive Interference in Steady State (3D CISS) MRI sequences of the inner ear should be done. Results from both studies should ascertain whether the cochlear duct is patent, ruling out any cochlear fibrosis or obstructive pathology. This patient’s HRCT and 3-D CISS MRI studies showed no such cochlear obliteration that would have posed intraoperative difficulties and constituted contraindications to EAS surgery (Figure 8). Surgical Technique for Hearing Preservation A variety of techniques have evolved over the years into what is now commonly called minimally invasive cochlear implantation. Using minimally invasive techniques, residual hearing can indeed be preserved in over 80%-90% of patients 3,4 Initially, a “Soft Cochleostomy” technique was introduced. This entailed careful low-speed drilling of the promontory with a Skeeter® drill (Medtronic Xomed, Jacksonville FL, USA) followed by the use of a mini-lancet to make an opening in the membranous labyrinth. This method avoids direct suctioning and prevents ingress of blood and bone dust into the intracochlear compartment. Also, for this method, the endosteum is left intact after drilling a cochleostomy antero-inferior to the round window. This allows proper placement of the electrode into the scala tympani with less chance of injury to the basilar membrane. Later, a round window approach was introduced, and it also proved to be a reliable way to preserve residual hearing during cochlear implantation. For this method, a more direct round window approach is performed after careful drilling of the round window niche. A limited incision is made just large enough to allow the electrode to be inserted. For both methods, after the endosteal or round window membrane incision is made with a micro lancet, a very flexible electrode of 20 mm length is slowly inserted. During the insertion process, the cochleostomy or round window is kept under direct vision so that insertion forces are minimized. Topical antibiotics and steroids are applied at this time to reduce any inflammatory or apoptotic reactions related to the trauma of opening the cochlea and introducing an electrode. Finally, a soft tissue plug is placed tightly around the electrode entry point into the membranous labyrinth to prevent perilymph leakage. New electrode designs that are thinner and more flexible are important contributors to the preservation of hearing. Postoperative Outcomes and Quality of Life After about 4-6 weeks from the time of surgery the EAS implant is switched on. Based on our experience and that of others,3 speech perception performance improves with prolonged experience with the implant. Roughly 1 ½ years post-surgery this patient has achieved dramatic improvement in hearing both in quiet and in noise using the EAS compared to using only the hearing aid component or the CI component alone. Figure 9 shows this dramatic improvement in free-field pure tone thresholds. Figure 10 demonstrates the speech perception following EAS implantation compared to pre-EAS implantation. Audiologic evaluation done at the PGH Ear Unit using 20 phonetically balanced Filipino words familiar to the patient in quiet and with 55 dB masking noise in the side of the implanted ear clearly showed an advantage with the EAS configuration compared to either hearing aid or CI component alone. Even with noise, this patient actually performed better presumably because he may have concentrated more with the introduction of masking noise. Another factor of course is that the words have now become familiar to the patient with the previous testing done in quiet. Notably, he reported great subjective improvement after only 10 months post-surgery.5 Interestingly the patient’s only complaint during his last follow-up was that he had not been offered bilateral EAS implantation. It is always important for the otolaryngologist to consider the quality of hearing and quality of life of patients with hearing loss. Intervention should not end with a referral note to a hearing aid center or dispenser. It is important to request proof of improvement not only of hearing thresholds but of speech perception outcomes in quiet and in noise. That is, one should document actual performance with the device in place, regardless of the type of device (hearing aid, an EAS device, or a Cochlear implant). Minimal disturbance of the remaining intact structures of the cochlea of patients with low frequency residual hearing can be achieved by employing a meticulous surgical technique, by using the advanced and flexible electrodes developed by some manufacturers, and instilling intraoperative antibiotics and steroids. Thus when one is faced with a ski-slope type audiogram it is likely the patient with this audiogram will not benefit from hearing aids. Such patients should be offered the option of EAS implantation which combines good acoustic stimulation with electric stimulation using a shorter (than conventional cochlear implantation) but very flexible electrode system. Counseling must also be done with a special emphasis on the risk of losing residual hearing, and noting that post-operative rehabilitation may take a long period of time. This patient now has a better quality of life than was obtainable from the most expensive and advanced hearing aids in the market, and has demonstrated a new implantable solution to partial deafness. Truly, EAS technology has opened a new era in prosthetic rehabilitation for hearing impaired adults and children.5 Acknowledgement Dr. Maria Rina Reyes-Quintos is gratefully acknowledged for performing all the excellent audiological testing following the surgery while Susan Javier and Angie Tongko of Manila Hearing Aid Center performed all the audiological testing prior to the surgery. Ms. Celina Ann Tobias, Professional Education Manager of Med-El is also credited with thanks for preparing the figures, reviewing the manuscript and interviewing the patient regarding his hearing performance following the surgery.

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Nace, Trevor. "My Science Life: Stephen Tsikalas - Professor Of Geography At Jacksonville State University." Science Trends, September 5, 2017. http://dx.doi.org/10.31988/scitrends.2625.

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"Roundtable: Pulmonary Hypertension Due to Left Heart Disease." Advances in Pulmonary Hypertension 14, no. 2 (January 1, 2015): 105–10. http://dx.doi.org/10.21693/1933-088x-14.2.105.

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Guest editor Teresa De Marco, MD, along with Brian Shapiro, MD, Mayo Clinic, Jacksonville, FL, convened a panel of experts to discuss the challenges in diagnosis and treatment and the emerging science regarding pulmonary hypertension due to left heart disease. Contributing to the engaging discussion were James Fang, MD, University of Utah School of Medicine; Barry Borlaug, MD, Mayo Clinic, Rochester, MN; and Srinivas Murali, MD, Allegheny Health Network, Pittsburgh, PA.

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Journal articles on the topic 'Jacksonville University'

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