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1

Wilks, Andrew F. Intracellular signal transduction: The JAK-STAT pathway. Springer, 1996.

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2

Decker, Thomas, and Mathias Müller, eds. Jak-Stat Signaling : From Basics to Disease. Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-0891-8.

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3

Wilks, Andrew F., and Ailsa G. Harpur. Intracellular Signal Transduction: The JAK-STAT Pathway. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-662-22050-4.

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4

Fleischmann, Roy. Signalling pathway inhibitors. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0081.

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Oral, small-molecule signalling pathway inhibitors, including ones that inhibit the JAK and SyK pathways, are currently in development for the treatment of rheumatoid arthritis (RA). Tofacitinib is an orally administered small-molecule inhibitor that targets the intracellular Janus kinase 3 and 1 (JAK1/3) molecules to a greater extent than JAK2 while baricitinib (formerly INCB028050) predominantly inhibits JAK1/2. Many of the proinflammatory cytokines implicated in the pathogenesis of RA utilize cell signalling that involves the JAK-STAT pathways and therefore inhibition of JAK-STAT signalling
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5

Wilks, Andrew F. Intracellular Signal Transduction: The Jak-Stat Pathway. Springer, 2013.

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6

Harpur, Ailsa G., and Andrew F. Wilks. The Jak-Stat Pathway (Molecular Biology Intelligence Unit). Springer, 1996.

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7

Jakstat Signalling Methods And Protocols. Humana Press, 2012.

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8

Goswami, Ritobrata. JAK-STAT Signaling in Diseases. Taylor & Francis Group, 2020.

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9

Goswami, Ritobrata. JAK-STAT Signaling in Diseases. CRC Press, 2020.

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10

Goswami, Ritobrata. JAK-STAT Signaling in Diseases. Taylor & Francis Group, 2020.

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11

Goswami, Ritobrata. JAK-STAT Signaling in Diseases. Taylor & Francis Group, 2020.

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12

Goswami, Ritobrata. JAK-STAT Signaling in Diseases. Taylor & Francis Group, 2020.

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13

Anastasis, Stephanou, ed. JAK-STAT pathway in disease. Landes Bioscience, 2009.

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14

Decker, Thomas, and Mathias Müller. Jak-Stat Signaling: From Basics to Disease. Springer, 2012.

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15

Decker, Thomas, and Mathias Müller. Jak-Stat Signaling: From Basics to Disease. Springer, 2012.

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16

The Jak-Stat pathway in hematopoiesis and disease. Landes Bioscience/Eurekah.com, 2002.

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17

Ward, Alister C. The Jak-Stat Pathway in Hematopoiesis and Disease (Molecular Biology Intelligence Unit, 20). Springer, 2002.

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18

Mahdavi, Alborz. Analysis of transient JAK/STAT signaling kinetics predicts control modules of stem cell fate control. 2006.

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