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Dissertations / Theses on the topic 'Jembrana'

Author: Grafiati

Published: 11 December 2022

Last updated: 31 July 2025

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1

Kertayadnya, Gde. "A study of Jembrana disease virus and its role in Jembrana disease in Bali cattle." Thesis, Kertayadnya, Gde (1994) A study of Jembrana disease virus and its role in Jembrana disease in Bali cattle. PhD thesis, Murdoch University, 1994. https://researchrepository.murdoch.edu.au/id/eprint/53281/.

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The literature on Jembrana disease, a disease apparently unique to Bali (Bos javanicus) cattle, was reviewed. Emphasis was placed on the comparative features of Jembrana disease and other diseases in cattle and some other animal species. A detailed study was made of the clinical and haematological changes in experimentally induced Jembrana disease in Bali cattle. The major clinical signs were an elevated rectal body temperature persisting for 7 days (range 5 to 12 days), lethargy, anorexia, and enlargement of the superficial lymph nodes. A mild ocular and nasal discharge, diarrhoea with bl

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2

Peterson, Shane. "Genome evolution of Jembrana disease virus." Thesis, Peterson, Shane (2011) Genome evolution of Jembrana disease virus. PhD thesis, Murdoch University, 2011. https://researchrepository.murdoch.edu.au/id/eprint/21253/.

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3

Chadwick, Brad. "Genetic studies of Jembrana disease virus." Thesis, Chadwick, Brad (1995) Genetic studies of Jembrana disease virus. PhD thesis, Murdoch University, 1995. https://researchrepository.murdoch.edu.au/id/eprint/53230/.

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The complete nucleotide sequence of the RNA genome of Jembrana disease virus (JDV) was obtained. The genome was that of a typical lentivirus. In addition to the gag, pol and env genes and flanking long terminal repeats that characterize all retroviruses, a number of accessory genes were identified. These were small, often multiply spliced open reading frames in the central and 3’ terminal regions of the genome and included tat and rev. The sequence data indicated that JDV was closely related to American isolates of bovine immunodeficiency virus (BIV), the only previously identified bovine lent

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4

Soeharsono, Son. "Studies of Jembrana disease in Bali cattle." Thesis, Soeharsono, Son (1993) Studies of Jembrana disease in Bali cattle. PhD thesis, Murdoch University, 1993. https://researchrepository.murdoch.edu.au/id/eprint/53229/.

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The clinical and haematological changes in experimentally induced Jembrana disease in Bali cattle (Bos javanicus) were described. The major clinical signs were an elevated rectal body temperature persisting for 7 days (range 5 to 12 days), lethargy, anorexia, enlargement of the superficial lymph nodes, a mild ocular and nasal discharge, diarrhoea with blood in the faeces, and pallor of the mucous membranes. Not all of these changes occurred in all affected cattle. The major haematological changes included a leukopenia, lymphopenia, eosinopenia and a slight neutropenia, a mild thrombocytopenia,

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5

com, ssetiyan@gmail, and Surachmi Setiyaningsih. "Molecular andImmunogenic Analysis of Jembrana Disease Virus Tat." Murdoch University, 2006. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20061019.150917.

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Jembrana disease is an acute and severe disease of Bali cattle (Bos javanicus) endemic in Indonesia that is caused by a bovine lentivirus designated Jembrana disease virus (JDV). Previous studies have demonstrated that it is possible to induce a protective immunity against the disease by immunisation with a crude whole virus vaccine prepared from the tissues of infected cattle. This vaccine has been demonstrated to ameliorate the clinical signs of disease resulting from exposure to virus infection but a safer vaccine amenable to commercial production techniques is required. JDV, like all lenti

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6

au, w. ditcham@murdoch edu, and William Ditcham. "The development of recombinant vaccines against Jembrana disease." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20071119.94111.

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Jembrana disease virus (JDV) is a lentivirus causing an acute infection with a 17% case fatality rate in Bali cattle in Indonesia. Control of the disease is currently achieved by identification of infected areas and restriction of cattle movement. A detergent-inactivated whole virus tissue-derived vaccine is sometimes employed in affected areas. This thesis reports initial attempts to produce genetically engineered vaccines to replace the inactivated tissue-derived vaccine, which as it is made from homogenised spleen of infected animals, is expensive to produce and could contain adventitious

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7

Ditcham, William. "The development of recombinant vaccines against Jembrana disease." Thesis, Ditcham, William (2007) The development of recombinant vaccines against Jembrana disease. PhD thesis, Murdoch University, 2007. https://researchrepository.murdoch.edu.au/id/eprint/438/.

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Jembrana disease virus (JDV) is a lentivirus causing an acute infection with a 17% case fatality rate in Bali cattle in Indonesia. Control of the disease is currently achieved by identification of infected areas and restriction of cattle movement. A detergent-inactivated whole virus tissue-derived vaccine is sometimes employed in affected areas. This thesis reports initial attempts to produce genetically engineered vaccines to replace the inactivated tissue-derived vaccine, which as it is made from homogenised spleen of infected animals, is expensive to produce and could contain adventitio

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8

Ditcham, William. "The development of recombinant vaccines against Jembrana disease." Ditcham, William (2007) The development of recombinant vaccines against Jembrana disease. PhD thesis, Murdoch University, 2007. http://researchrepository.murdoch.edu.au/438/.

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Jembrana disease virus (JDV) is a lentivirus causing an acute infection with a 17% case fatality rate in Bali cattle in Indonesia. Control of the disease is currently achieved by identification of infected areas and restriction of cattle movement. A detergent-inactivated whole virus tissue-derived vaccine is sometimes employed in affected areas. This thesis reports initial attempts to produce genetically engineered vaccines to replace the inactivated tissue-derived vaccine, which as it is made from homogenised spleen of infected animals, is expensive to produce and could contain adventitiou

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9

au, M. Stewart@murdoch edu, and Meredith Stewart. "An investigation into aspects of the replication of Jembrana disease virus." Murdoch University, 2005. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20051222.104106.

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Jembrana disease virus (JDV) is an acutely pathogenic lentivirus affecting Bali cattle in Indonesia. The inability to propagate the virus in vitro has made it difficult to quantitate JDV and determine the kinetics of virus replication during the acute disease process. Reported for the first time are 2 techniques that enable quantification of the virus, and the use of these techniques to quantify the virus load in plasma of cattle during the acute disease process. The 2 techniques were a qualitative one-step JDV real-time reverse-transcription polymerase chain reaction (qRT-PCR) assay for the d

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10

Setiyaningsih, Surachmi. "Molecular and immunogenic analysis of Jembrana disease virus Tat." Thesis, Setiyaningsih, Surachmi (2006) Molecular and immunogenic analysis of Jembrana disease virus Tat. PhD thesis, Murdoch University, 2006. https://researchrepository.murdoch.edu.au/id/eprint/299/.

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Jembrana disease is an acute and severe disease of Bali cattle (Bos javanicus) endemic in Indonesia that is caused by a bovine lentivirus designated Jembrana disease virus (JDV). Previous studies have demonstrated that it is possible to induce a protective immunity against the disease by immunisation with a crude whole virus vaccine prepared from the tissues of infected cattle. This vaccine has been demonstrated to ameliorate the clinical signs of disease resulting from exposure to virus infection but a safer vaccine amenable to commercial production techniques is required. JDV, like all l

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11

Setiyaningsih, Surachmi. "Molecular and immunogenic analysis of Jembrana disease virus Tat." Setiyaningsih, Surachmi (2006) Molecular and immunogenic analysis of Jembrana disease virus Tat. PhD thesis, Murdoch University, 2006. http://researchrepository.murdoch.edu.au/299/.

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Jembrana disease is an acute and severe disease of Bali cattle (Bos javanicus) endemic in Indonesia that is caused by a bovine lentivirus designated Jembrana disease virus (JDV). Previous studies have demonstrated that it is possible to induce a protective immunity against the disease by immunisation with a crude whole virus vaccine prepared from the tissues of infected cattle. This vaccine has been demonstrated to ameliorate the clinical signs of disease resulting from exposure to virus infection but a safer vaccine amenable to commercial production techniques is required. JDV, like all l

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12

Singh, Meenu. "Introduction of recombinant antigens against Jembrana Disease Virus into plants." Thesis, Singh, Meenu (2010) Introduction of recombinant antigens against Jembrana Disease Virus into plants. Masters by Research thesis, Murdoch University, 2010. https://researchrepository.murdoch.edu.au/id/eprint/2347/.

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Jembrana disease virus (JDV) is a bovine lentivirus that causes an acute severe disease syndrome in banteng cattle (Bos javanicus) in Indonesia. In order to develop a vaccine, JDV capsid (CA) protein together with transactivator of transcription (Tat) have been produced and expressed in a microbial system with limited success, but surface unit glycoprotein (SU) is difficult to produce in E.coli as it requires glycosylation and post-translational modification. In an approach to overcome the limitations of a microbial antigen expression system, in this study, JDV fused CA-Tat and SU regions were

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13

Hartaningsih, Nining. "Aetiological and immunological aspects of Jembrana disease in Bali cattle." Thesis, Hartaningsih, Nining (1993) Aetiological and immunological aspects of Jembrana disease in Bali cattle. PhD thesis, Murdoch University, 1993. https://researchrepository.murdoch.edu.au/id/eprint/53267/.

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The clinico-pathological changes in experimentally induced Jembrana disease in Bali cattle (Bos javanicus) were determined as a basis for the differential diagnosis of the disease and increased understanding of the pathogenesis of the disease process. The incubation period varied from 4 to 12 days. The major clinical signs in the experimentally infected cattle were an elevated rectal body temperature persisting for 5 to 12 days, lethargy, anorexia, and enlargement of the superficial lymph nodes. The case fatality rate was 17%. The major haematological changes included a leukopenia characterize

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14

Stewart, Meredith Ellen. "An investigation into aspects of the replication of Jembrana disease virus /." Access via Murdoch University Digital Theses Project, 2005. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20051222.104106.

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15

Stewart, Meredith. "An investigation into aspects of the replication of Jembrana disease virus." Thesis, Stewart, Meredith (2005) An investigation into aspects of the replication of Jembrana disease virus. PhD thesis, Murdoch University, 2005. https://researchrepository.murdoch.edu.au/id/eprint/348/.

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Jembrana disease virus (JDV) is an acutely pathogenic lentivirus affecting Bali cattle in Indonesia. The inability to propagate the virus in vitro has made it difficult to quantitate JDV and determine the kinetics of virus replication during the acute disease process. Reported for the first time are 2 techniques that enable quantification of the virus, and the use of these techniques to quantify the virus load in plasma of cattle during the acute disease process. The 2 techniques were a qualitative one-step JDV real-time reverse-transcription polymerase chain reaction (qRT-PCR) assay for the d

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16

Stewart, Meredith. "An investigation into aspects of the replication of Jembrana disease virus." Stewart, Meredith (2005) An investigation into aspects of the replication of Jembrana disease virus. PhD thesis, Murdoch University, 2005. http://researchrepository.murdoch.edu.au/348/.

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Abstract:

Jembrana disease virus (JDV) is an acutely pathogenic lentivirus affecting Bali cattle in Indonesia. The inability to propagate the virus in vitro has made it difficult to quantitate JDV and determine the kinetics of virus replication during the acute disease process. Reported for the first time are 2 techniques that enable quantification of the virus, and the use of these techniques to quantify the virus load in plasma of cattle during the acute disease process. The 2 techniques were a qualitative one-step JDV real-time reverse-transcription polymerase chain reaction (qRT-PCR) assay for the d

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17

Rachmat, Judhi. "Improved methods for production and characterisation of Jembrana disease virus proteins." Thesis, Rachmat, Judhi (2010) Improved methods for production and characterisation of Jembrana disease virus proteins. PhD thesis, Murdoch University, 2010. https://researchrepository.murdoch.edu.au/id/eprint/3490/.

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Jembrana disease is an acute disease of Bali cattle (Bos javanicus) in Indonesia caused by Jembrana disease virus (JDV), a lentivirus most closely related to Bovine immunodeficiency virus. Control of the disease in Bali cattle, which are important to the economy of Indonesia, is dependent on the continued availability of protein antigens for immunosurveillance procedures that have been developed. Further investigation is also required to characterise of the proteins of JDV and to provide methods of producing commercial quantities of recombinant proteins for vaccine manufacture. A problem w

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18

Tenaya, I. Wayan Masa. "Studies of the pathogenesis of Jembrana disease virus infection in Bos javanicus." Thesis, Tenaya, I.Wayan Masa (2010) Studies of the pathogenesis of Jembrana disease virus infection in Bos javanicus. PhD thesis, Murdoch University, 2010. https://researchrepository.murdoch.edu.au/id/eprint/3375/.

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Jembrana disease was reported initially in Bali cattle (Bos javanicus) on Bali island in 1964 and the causative agent was subsequently identified as a bovine lentivirus and designated Jembrana disease virus (JDV). This atypical lentivirus causes an acutely pathogenic disease that is associated with clinical signs and pathological lesions attributable to a disease primarily affecting the lymphoid system. Based on the intense proliferation of cells in the parafollicular (T-cell) areas of lymphoid tissue it has been assumed that the cellular tropism of the virus was for T-cells. An initial in

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19

McNab, Tegan Josephine. "An analysis of Bovine immunodeficiency virus and Jembrana disease virus infections in Bos javanicus." Thesis, McNab, Tegan Josephine (2010) An analysis of Bovine immunodeficiency virus and Jembrana disease virus infections in Bos javanicus. PhD thesis, Murdoch University, 2010. https://researchrepository.murdoch.edu.au/id/eprint/4153/.

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Two closely related bovine lentiviruses have been described, Jembrana disease virus (JDV) and Bovine immunodeficiency virus (BIV), that produce very different clinical manifestations in infected cattle. JDV causes an acute disease with a case fatality rate of about 21% in Bos javanicus (Bali cattle) and is endemic in the cattle population of parts of Indonesia. BIV produces a subclinical infection in Bos taurus and buffalo and serological evidence has shown that this virus has a worldwide distribution, possibly including Indonesia. Attempts were made to confirm a previous report that BIV w

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20

au, josh lewis@meddent uwa edu, and Joshua Richard Lewis. "Recombinant proteins as vaccines and diagnostic antigens for the control of Jembrana disease virus infection in Indonesia." Murdoch University, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20100203.135558.

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Jembrana disease virus (JDV) is a lentivirus associated with an acute disease syndrome of Bali cattle (Bos javanicus) in Indonesia. Control of Jembrana disease currently involves serological monitoring of infection in endemic areas, restriction of movement of cattle from these areas and ring-vaccination around outbreaks of the disease with a tissue-derived inactivated-virus vaccine. Earlier investigations at Murdoch University resulted in a vaccine combining a mix of recombinant capsid (CA) and Tat proteins that ameliorated the clinical signs of JDV infection in vaccinated cattle. This thesis

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21

Lewis, Joshua Richard. "Recombinant proteins as vaccines and diagnostic antigens for the control of Jembrana disease virus infection in Indonesia." Lewis, Joshua Richard (2008) Recombinant proteins as vaccines and diagnostic antigens for the control of Jembrana disease virus infection in Indonesia. PhD thesis, Murdoch University, 2008. http://researchrepository.murdoch.edu.au/1806/.

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embrana disease virus (JDV) is a lentivirus associated with an acute disease syndrome of Bali cattle (Bos javanicus) in Indonesia. Control of Jembrana disease currently involves serological monitoring of infection in endemic areas, restriction of movement of cattle from these areas and ring-vaccination around outbreaks of the disease with a tissue-derived inactivated-virus vaccine. Earlier investigations at Murdoch University resulted in a vaccine combining a mix of recombinant capsid (CA) and Tat proteins that ameliorated the clinical signs of JDV infection in vaccinated cattle. This thesis

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22

Lewis, Joshua. "Recombinant proteins as vaccines and diagnostic antigens for the control of Jembrana disease virus infection in Indonesia." Thesis, Lewis, Joshua (2008) Recombinant proteins as vaccines and diagnostic antigens for the control of Jembrana disease virus infection in Indonesia. PhD thesis, Murdoch University, 2008. https://researchrepository.murdoch.edu.au/id/eprint/1806/.

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embrana disease virus (JDV) is a lentivirus associated with an acute disease syndrome of Bali cattle (Bos javanicus) in Indonesia. Control of Jembrana disease currently involves serological monitoring of infection in endemic areas, restriction of movement of cattle from these areas and ring-vaccination around outbreaks of the disease with a tissue-derived inactivated-virus vaccine. Earlier investigations at Murdoch University resulted in a vaccine combining a mix of recombinant capsid (CA) and Tat proteins that ameliorated the clinical signs of JDV infection in vaccinated cattle. This thesis

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23

Ida, Bagus Mary Jane. "From the margins of history: a long Babad of Jembrana, Bali." Thesis, 2006. http://hdl.handle.net/1959.13/1312412.

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Research Doctorate - Doctor of Philosophy (PhD)<br>The island of Bali, as the 'Hindu' region of Indonesia, has been well studied by anthropologists, historians, and archaeologists from all corners of the globe. The results of this intense focus have served the purposes of various regimes of power that have swept over an often silenced population. From the colonial Dutch, to post colonial nationalism, to the neo-colonial New Order, powerful hegemonic forces contributed to shaping a Bali that was displayed to the world as a unitary Hindu domain in a sea of contrived Indonesian diversity. The cur

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24

Marchand, Claude. "Caractérisation des domaines fonctionnels de la protéine Rev de lentivirus." Thesis, 2020. http://hdl.handle.net/1866/24851.

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Dans la cellule, les ARN pré messagers contenant des introns sont normalement retenus au noyau par leur interaction avec des facteurs d’épissage. Cependant, les ARN partiellement et non épissés des rétrovirus doivent entrer dans le cytoplasme pour servir de matrice pour la synthèse de certaines protéines telles que Env, Gag et Gag-Pol ainsi que d’ARN génomique qui sera empaqueté dans les nouveaux virions. Un mécanisme post-transcriptionnel utilisé par les lentivirus pour éviter la séquestration nucléaire de ces ARNm dépend d’une protéine virale appelée Rev. Pour assurer sa fonction d’exportati

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